TWAS hub - PLGRKT

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1660	0.0440	1.6e-05	0.180	NA	0.160	NA	0.170	1.4e-14	NA	5.0e-13	NA	7.2e-14
2	GTEx	Adipose Visceral Omentum	0.1760	0.0530	3.3e-04	0.209	NA	0.180	NA	0.194	4.2e-11	NA	1.2e-09	NA	2.2e-10
3	GTEx	Adrenal Gland	0.3014	0.0888	5.0e-04	0.259	NA	0.215	NA	0.238	8.5e-10	NA	3.0e-08	NA	4.9e-09
4	GTEx	Artery Aorta	0.1550	0.0610	7.6e-03	0.110	NA	0.110	NA	0.105	1.2e-06	NA	1.3e-06	NA	2.2e-06
5	GTEx	Artery Coronary	0.3250	0.0840	1.8e-04	0.178	NA	0.128	NA	0.175	1.3e-06	NA	4.5e-05	NA	1.6e-06
6	GTEx	Artery Tibial	0.1614	0.0460	3.0e-05	0.181	NA	0.142	NA	0.177	4.2e-14	NA	3.1e-11	NA	8.5e-14
7	GTEx	Brain Cerebellum	0.3540	0.0970	1.2e-03	0.171	NA	0.068	NA	0.085	9.3e-06	NA	4.6e-03	NA	1.7e-03
8	GTEx	Breast Mammary Tissue	0.1710	0.0590	1.5e-03	0.148	NA	0.130	NA	0.121	4.9e-08	NA	3.4e-07	NA	9.2e-07
9	GTEx	Breast Mammary Tissue (Male)	0.1064	0.0984	1.8e-01	0.019	NA	0.042	NA	-0.002	1.1e-01	NA	3.8e-02	NA	3.6e-01
10	GTEx	Breast Mammary Tissue (Female)	0.1731	0.0751	1.5e-02	0.077	NA	0.093	NA	0.112	2.6e-03	NA	9.9e-04	NA	3.2e-04
11	GTEx	Cells Transformed fibroblasts	0.2240	0.0570	2.7e-06	0.144	NA	0.144	NA	0.150	6.3e-11	NA	6.6e-11	NA	2.4e-11
12	GTEx	Colon Sigmoid	0.2540	0.0780	6.5e-04	0.210	NA	0.119	NA	0.160	5.8e-08	NA	5.7e-05	NA	2.7e-06
13	GTEx	Colon Transverse	0.3260	0.0660	1.1e-07	0.222	NA	0.205	NA	0.229	7.2e-11	NA	4.5e-10	NA	3.1e-11
14	GTEx	Esophagus Mucosa	0.2740	0.0540	1.9e-09	0.275	NA	0.228	NA	0.270	1.5e-18	NA	2.7e-15	NA	3.2e-18
15	GTEx	Esophagus Muscularis	0.2750	0.0570	4.7e-08	0.245	NA	0.194	NA	0.231	5.3e-15	NA	5.9e-12	NA	3.5e-14
16	GTEx	Lung	0.1574	0.0421	2.6e-05	0.109	NA	0.098	NA	0.101	1.1e-08	NA	6.6e-08	NA	4.0e-08
17	GTEx	Nerve Tibial	0.1679	0.0508	2.4e-04	0.175	NA	0.201	NA	0.161	1.9e-12	NA	3.2e-14	NA	1.7e-11
18	GTEx	Ovary	0.4510	0.1290	1.3e-03	0.111	NA	0.295	NA	0.265	1.2e-03	NA	5.8e-08	NA	3.2e-07
19	GTEx	Skin Not Sun Exposed Suprapubic	0.2700	0.0630	8.8e-07	0.198	NA	0.218	NA	0.211	4.2e-11	NA	3.4e-12	NA	8.5e-12
20	GTEx	Skin Sun Exposed Lower leg	0.2420	0.0540	7.1e-08	0.118	NA	0.115	NA	0.144	5.3e-10	NA	9.6e-10	NA	5.9e-12
21	GTEx	Stomach	0.4390	0.1240	5.5e-04	0.033	NA	0.018	NA	0.021	1.1e-02	NA	4.3e-02	NA	3.2e-02
22	GTEx	Thyroid	0.1620	0.0510	5.5e-05	0.121	NA	0.094	NA	0.103	1.7e-09	NA	1.2e-07	NA	2.8e-08
23	METSIM	Adipose	0.1340	0.0277	8.8e-15	0.154	0.111	0.146	0.146	0.156	2.6e-22	3.0e-16	3.5e-21	2.9e-21	1.2e-22
24	ROSMAP	Brain Pre-frontal Cortex	0.0801	0.0283	8.1e-04	0.035	0.033	0.015	0.033	0.021	2.2e-05	4.2e-05	4.6e-03	3.8e-05	9.7e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Ulcerative Colitis	5.0	7.2	18.6	2.7	2.7	2.6	2.8	3.0	2.7	2.1	2.0	4.3	1.6	2.7	2.7	3.3	2.8	2.6	2.9	1.3	2.3	2.8	2.8	2.1	2.6	2.9	2.9
Had menopause	4.8	6.0	10.1	-2.9	-2.9	-2.1	-2.6	-2.9	-2.9	-0.2	-1.8	-1.2	-0.5	-2.7	-3.0	-2.4	-2.9	-2.9	-2.3	-3.2	-2.5	-2.5	-2.3	-2.5	-2.7	-2.7	-1.6
Qualifications: O levels/GCSEs or equivalent	4.6	7.3	12.2	2.9	2.9	2.9	3.0	3.1	2.9	1.0	2.5	1.4	1.0	3.1	2.9	3.1	2.9	2.9	3.1	1.8	2.8	3.5	2.9	2.4	2.8	3.2	1.7
Illnesses of siblings: Diabetes	4.1	5.0	8.5	-2.6	-2.5	-2.3	-2.6	-1.8	-2.5	-1.5	-2.3	-0.9	-1.4	-2.9	-2.5	-2.2	-2.7	-2.5	-2.0	-2.0	-1.4	-2.6	-2.3	-2.2	-2.5	-2.7	-1.4
Bipolar Disorder (2011)	4.0	3.8	8.0	-1.8	-1.8	-1.9	-1.7	-2.8	-1.8	-2.1	-1.6	-1.4	-2.3	-1.7	-1.8	-2.0	-1.8	-1.8	-2.6	-1.6	-1.3	-1.6	-2.0	-2.3	-1.9	-1.9	-2.6
Hayfever/allergic rhinitis (self-reported)	4.0	5.4	13.2	2.2	2.2	2.2	2.2	1.6	2.2	2.7	2.7	3.6	2.6	2.4	2.2	2.0	2.2	2.2	2.4	1.7	3.4	2.1	2.4	0.7	2.2	2.3	1.3
Ever highly irritable/argumentative for 2 days	3.8	4.5	8.4	-2.2	-2.2	-2.9	-2.4	-2.3	-2.2	-0.8	-1.6	-0.7	-0.7	-2.3	-2.2	-2.6	-2.2	-2.2	-2.4	-2.1	-2.5	-2.8	-2.4	-0.9	-2.2	-2.4	-1.6
Heel bone mineral density (BMD) T-score, automated (left)	3.7	8.4	12.0	-3.1	-3.1	-3.0	-3.2	-3.2	-3.1	-0.4	-2.4	-2.2	-0.5	-3.1	-3.1	-3.3	-3.1	-3.1	-3.0	-2.7	-3.5	-3.1	-2.8	-3.2	-3.0	-3.2	-2.5
Asthma (self-reported)	3.7	7.3	18.7	2.8	2.8	3.3	3.1	2.7	2.8	1.1	2.4	3.5	1.2	3.0	2.8	3.5	2.8	2.7	2.3	2.0	4.3	2.3	2.8	1.2	2.5	2.9	1.6
Asthma	3.4	6.6	17.0	2.6	2.7	3.1	2.9	2.4	2.6	1.0	2.2	3.6	1.3	2.9	2.6	3.3	2.6	2.6	2.0	1.9	4.1	2.2	2.7	1.0	2.4	2.8	1.5
Allergy	3.1	7.1	32.1	-2.5	-2.6	-3.3	-2.8	-3.1	-2.5	-0.2	-1.8	-4.4	-0.1	-2.7	-2.5	-3.2	-2.5	-2.4	-2.4	-1.7	-5.7	-2.2	-2.4	-0.5	-2.1	-2.7	-0.1
Respiratory disease	3.0	6.6	15.4	2.5	2.6	3.5	2.9	2.4	2.5	0.2	2.4	3.9	0.6	2.8	2.5	3.5	2.5	2.5	2.4	1.6	3.9	2.2	2.7	0.8	2.3	2.7	1.8
Mouth/teeth dental problems	2.9	4.5	6.4	-2.2	-2.2	-2.3	-2.1	-1.4	-2.2	-2.4	-2.5	-1.3	-2.4	-2.3	-2.2	-2.4	-2.1	-2.2	-2.5	-1.0	0.3	-2.5	-2.2	-1.5	-2.3	-2.2	-2.2
Ulcerative Colitis (UC)	2.8	5.3	17.1	2.3	2.3	2.1	2.5	2.6	2.3	0.9	1.1	4.1	0.0	2.2	2.4	2.7	2.4	2.2	2.5	0.9	3.0	2.1	2.3	2.4	2.0	2.4	2.4
Average weekly spirits intake	2.8	3.5	5.2	-2.0	-2.0	-1.8	-2.1	-1.6	-2.0	-2.3	-1.7	-0.3	-1.9	-2.0	-2.0	-1.5	-2.0	-2.0	-2.0	-1.2	-0.3	-2.1	-2.2	-1.9	-2.1	-2.0	-2.3
Frequency of tiredness / lethargy in last 2 weeks	2.8	4.5	7.1	-2.3	-2.3	-2.5	-2.3	-1.9	-2.3	-1.2	-1.9	-0.8	-0.9	-2.3	-2.3	-2.7	-2.3	-2.3	-2.1	-2.4	-2.3	-2.1	-2.1	-1.1	-2.3	-2.2	-2.4
Knee pain experienced in last month	2.7	4.2	7.3	-2.2	-2.2	-2.7	-2.0	-1.8	-2.2	-1.5	-1.7	-0.7	-1.5	-2.2	-2.2	-2.7	-2.1	-2.2	-2.6	-2.0	-1.1	-2.1	-2.2	-1.9	-2.1	-2.2	-1.6
Medication: Lisinopril	2.7	3.5	7.5	-1.9	-1.9	-2.7	-2.1	-2.4	-1.9	0.1	-1.1	-1.4	-0.2	-2.0	-1.9	-2.6	-1.9	-1.9	-1.8	-1.7	-1.8	-1.7	-1.9	-1.7	-1.9	-2.0	-1.9
Neuroticism (2016)	2.6	3.7	5.9	2.3	2.2	1.0	2.0	1.7	2.3	1.5	2.2	1.7	1.8	2.1	2.3	1.4	2.2	2.3	2.0	2.4	1.8	1.6	1.8	0.5	2.4	2.0	1.2
Commuting to job workplace: Walk	2.6	2.8	9.4	-1.5	-1.5	-0.9	-1.6	-1.3	-1.5	-3.1	-2.1	-1.0	-2.9	-1.3	-1.6	-1.1	-1.5	-1.5	-2.0	-1.1	-0.2	-1.7	-1.9	-0.9	-1.9	-1.5	-1.8
Myopia	2.6	3.8	6.0	-2.2	-2.2	-1.9	-1.9	-1.5	-2.2	-1.2	-2.4	-0.1	-1.6	-2.1	-2.2	-2.0	-2.3	-2.3	-1.9	-2.3	-1.2	-2.4	-1.8	-1.8	-2.3	-2.0	-1.4
Irritable Bowel Disease (IBD)	2.5	5.9	17.1	2.5	2.5	2.5	2.6	2.2	2.5	0.3	1.6	4.1	-0.4	2.5	2.6	2.9	2.7	2.4	2.2	1.1	4.1	2.1	2.1	2.1	2.0	2.4	1.9
Multivitamins +/- minerals	2.5	3.2	5.7	-1.7	-1.7	-1.6	-1.9	-1.3	-1.7	-2.4	-2.1	-1.7	-2.2	-1.8	-1.7	-1.6	-1.6	-1.7	-1.9	-0.6	-1.8	-2.0	-2.1	-1.0	-1.8	-1.8	-2.4
Qualifications: College or University degree	2.5	7.9	11.6	3.0	3.0	2.7	3.0	3.3	3.0	2.3	2.8	2.0	2.0	3.1	2.9	2.8	2.9	3.0	3.3	2.7	2.7	3.4	3.0	1.4	3.0	3.0	2.2
Heel bone mineral density (BMD) T-score, automated (right)	2.4	5.5	7.9	-2.6	-2.6	-2.5	-2.6	-2.7	-2.6	0.4	-1.8	-0.8	0.1	-2.7	-2.6	-2.7	-2.6	-2.6	-2.1	-2.5	-2.5	-2.4	-2.3	-2.8	-2.4	-2.7	-1.9
Illnesses of siblings	2.4	3.4	5.5	2.2	2.2	1.8	2.2	1.4	2.2	0.7	1.8	1.6	0.3	2.3	2.2	1.8	2.3	2.2	1.7	1.7	0.9	1.9	1.8	1.9	2.0	2.0	0.6
Eye problems/disorders: None of the above	2.4	2.8	5.5	-1.7	-1.7	-1.6	-1.8	-1.3	-1.6	-1.0	-1.9	-2.3	-1.2	-1.7	-1.7	-1.6	-1.6	-1.7	-1.6	-1.6	-1.6	-2.1	-1.7	-1.5	-1.8	-1.7	-1.5
Ever taken oral contraceptive pill	2.4	2.7	4.0	1.8	1.8	1.4	1.3	1.5	1.9	1.2	1.4	0.1	1.7	1.9	1.9	1.6	1.9	1.9	1.8	2.0	1.4	1.9	1.4	2.0	2.0	1.8	0.6
Alzheimer’s Disease (in father)	2.3	2.5	4.1	-1.7	-1.8	-1.9	-1.7	-2.0	-1.7	-0.7	-1.1	-0.9	-0.6	-1.6	-1.7	-1.8	-1.6	-1.7	-1.9	-1.5	-1.1	-2.0	-1.7	-1.5	-1.6	-1.7	-1.4
Number of full brothers	2.2	2.7	4.8	-1.7	-1.6	-1.6	-2.0	-1.8	-1.6	-1.8	-1.7	-1.8	-1.3	-1.7	-1.6	-1.7	-1.6	-1.6	-1.9	-0.7	-0.6	-1.9	-1.9	-1.2	-1.7	-1.6	-2.2
Hayfever, allergic rhinitis or eczema	2.1	4.5	25.4	1.8	1.9	2.6	2.0	2.8	1.8	0.8	1.5	3.6	0.8	2.0	1.8	2.3	1.8	1.7	2.0	1.4	5.0	1.7	1.9	0.2	1.6	2.1	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.1	2.4	6.4	1.1	1.2	1.8	1.5	0.8	1.1	2.4	1.8	2.5	2.4	1.6	1.1	1.6	1.0	1.1	1.3	0.9	0.2	1.8	1.9	1.0	1.4	1.6	1.9
Fractured/broken bones in last 5 years	2.1	2.7	4.7	1.9	1.8	1.2	1.5	1.4	1.9	2.0	1.4	1.1	1.3	1.5	1.9	1.7	1.9	1.9	1.6	2.2	1.0	1.3	1.4	1.8	1.8	1.5	1.6
Migraine (self-reported)	2.0	2.4	4.1	1.9	1.8	1.1	1.7	1.6	1.9	1.2	1.4	0.3	1.1	1.7	1.9	1.4	2.0	1.9	1.5	1.3	1.5	1.6	1.5	1.4	2.0	1.6	0.9
Emphysema/chronic bronchitis	1.9	2.2	5.4	1.5	1.6	2.1	1.5	1.1	1.5	-0.1	1.1	2.3	-0.1	1.6	1.6	1.9	1.6	1.5	0.9	1.9	1.6	1.2	1.3	1.4	1.3	1.6	1.1
Worrier / anxious feelings	1.7	3.2	7.0	-1.8	-1.7	-1.2	-1.7	-0.8	-1.8	-2.6	-2.0	-1.7	-2.5	-1.8	-1.9	-1.5	-1.8	-1.8	-1.8	-2.0	-0.8	-1.8	-1.9	-1.9	-1.8	-1.7	-1.6
Mouth/teeth dental problems: Dentures	1.7	2.8	5.7	1.9	1.9	1.6	1.6	1.4	1.9	1.2	1.8	-0.0	1.1	1.8	1.9	1.8	1.8	1.9	2.0	1.2	-1.1	1.7	1.4	1.7	1.8	1.8	2.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.7	2.0	3.5	-1.6	-1.6	-1.1	-1.3	-1.7	-1.6	-0.8	-1.2	-1.8	-0.8	-1.3	-1.6	-1.2	-1.6	-1.6	-1.4	-1.6	-1.9	-1.0	-1.3	-0.9	-1.6	-1.3	-0.9
Illnesses of father: None of the above (group 1)	1.7	2.1	4.2	1.5	1.5	1.8	1.5	2.0	1.5	-0.6	0.9	1.0	-0.7	1.3	1.5	1.9	1.6	1.5	1.4	1.1	1.5	1.3	1.3	1.4	1.3	1.5	2.0
Exposure to tobacco smoke outside home	1.6	2.1	4.0	-1.9	-1.9	-0.9	-1.4	-1.2	-1.9	0.2	-0.9	0.7	-0.1	-1.8	-2.0	-1.6	-2.0	-1.9	-1.2	-2.0	-0.6	-1.3	-1.0	-1.5	-1.8	-1.6	-0.7
Pain experienced in last month	1.6	2.6	6.9	2.0	2.0	1.7	1.6	1.4	2.0	-0.3	1.4	-0.1	0.1	2.0	2.0	1.8	1.9	2.0	1.6	2.6	0.3	1.8	1.3	0.5	1.8	1.8	1.5
Depressed Affect (Nagel 2018)	1.5	3.2	5.1	-1.6	-1.7	-2.1	-1.6	-1.6	-1.6	-2.1	-1.6	-2.2	-1.3	-1.8	-1.7	-2.2	-1.7	-1.6	-1.6	-1.5	-1.7	-1.6	-1.8	-2.0	-1.7	-1.8	-2.3
Hearing difficulty/problems: Yes	1.5	2.2	5.4	-1.6	-1.6	-2.3	-1.8	-1.9	-1.6	-0.6	-0.8	-0.6	0.2	-1.5	-1.6	-2.0	-1.6	-1.5	-1.7	-1.1	-1.3	-1.6	-1.6	-1.2	-1.4	-1.5	-1.2
Leg fat percentage (right)	1.5	5.5	20.8	-2.2	-2.3	-2.7	-2.3	-2.7	-2.2	0.9	-1.1	-2.8	1.2	-2.3	-2.2	-2.6	-2.3	-2.2	-1.7	-2.8	-4.6	-2.0	-1.8	-2.5	-2.0	-2.5	-1.6
Heart attack/myocardial infarction (self-reported)	1.5	2.0	4.6	-1.2	-1.3	-1.9	-1.4	-1.3	-1.2	-1.4	-1.4	-2.1	-1.0	-1.4	-1.3	-1.6	-1.3	-1.2	-1.3	-1.5	-2.1	-0.7	-1.4	-0.9	-1.2	-1.6	-1.1
Type 2 Diabetes (T2D) (2012)	1.4	1.6	4.8	1.5	1.5	0.6	1.1	1.0	1.6	1.0	1.2	-0.0	0.6	1.2	1.6	1.1	1.5	1.6	0.9	1.3	-0.7	1.0	1.0	2.2	1.6	1.3	1.7
Ever used hormone-replacement therapy (HRT)	1.4	1.8	3.0	-1.6	-1.6	-1.3	-1.5	-1.7	-1.6	-0.3	-1.2	-0.1	-0.4	-1.6	-1.6	-1.3	-1.7	-1.6	-1.3	-1.7	-0.4	-1.3	-1.3	-0.9	-1.5	-1.6	-1.1
Fed-up feelings	1.4	2.6	3.5	-1.6	-1.6	-1.9	-1.5	-0.9	-1.6	-1.8	-1.7	-1.5	-1.3	-1.9	-1.6	-1.9	-1.6	-1.6	-1.4	-1.8	-1.6	-1.7	-1.4	-1.3	-1.6	-1.7	-1.8
Length of working week for main job	1.4	1.5	2.5	-1.5	-1.5	-0.8	-1.5	-1.5	-1.6	-0.0	-0.8	0.4	-0.3	-1.3	-1.6	-1.3	-1.5	-1.6	-1.3	-1.2	-0.5	-1.0	-1.3	-1.2	-1.4	-1.3	-1.0
Commuting to job workplace: Public transport	1.4	1.7	2.9	1.7	1.6	0.9	1.4	1.6	1.7	0.4	1.2	0.7	0.7	1.5	1.7	1.1	1.6	1.7	1.5	1.2	1.0	1.4	1.3	0.1	1.7	1.4	0.3
Leg fat percentage (left)	1.4	5.1	19.2	-2.1	-2.2	-2.6	-2.2	-2.6	-2.1	0.9	-1.1	-2.8	1.4	-2.2	-2.1	-2.5	-2.2	-2.1	-1.6	-2.6	-4.4	-1.8	-1.7	-2.5	-1.9	-2.4	-1.4
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	6.5	1.0	1.0	1.0	0.9	0.9	1.0	2.5	1.3	0.3	2.2	1.1	1.0	1.2	0.9	1.0	1.9	0.1	-0.7	1.3	1.2	-0.4	1.3	1.2	0.6
High blood pressure (siblings)	1.3	1.9	4.8	-1.5	-1.5	-1.3	-1.5	-1.1	-1.5	-0.1	-1.5	-2.2	0.1	-1.7	-1.5	-1.4	-1.6	-1.5	-1.0	-0.9	-1.6	-1.6	-1.1	-1.6	-1.3	-1.4	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.7	4.9	1.7	1.7	1.2	1.9	1.7	1.7	1.3	2.0	1.2	1.2	1.8	1.7	1.1	1.7	1.7	1.9	2.2	1.5	1.3	1.8	0.8	1.9	1.8	1.4
Crohns Disease (2012)	1.2	1.9	6.4	1.5	1.5	1.5	1.3	0.8	1.5	0.3	1.3	2.3	0.2	1.5	1.6	1.7	1.6	1.4	1.0	1.4	2.5	1.0	1.0	0.6	1.3	1.2	1.1
LDL Cholesterol	1.2	1.9	3.1	1.6	1.6	1.3	1.4	1.3	1.6	0.3	1.3	0.4	0.1	1.6	1.7	1.4	1.6	1.7	1.8	1.2	1.2	1.4	1.3	1.3	1.4	1.6	0.6
Primary Biliary Cirrhosis	1.2	1.7	3.3	-1.6	-1.6	-1.4	-1.5	-1.2	-1.6	0.8	-0.5	-1.8	0.6	-1.3	-1.6	-1.1	-1.5	-1.6	-0.8	-1.7	-0.7	-1.7	-1.0	-1.3	-1.4	-1.1	0.1
Cardiovascular Disease	1.2	4.1	8.2	-2.4	-2.3	-1.4	-1.8	-2.0	-2.4	-1.3	-1.8	-2.9	-1.1	-2.1	-2.4	-1.8	-2.3	-2.3	-2.2	-1.8	-2.3	-1.6	-1.7	-1.7	-2.3	-2.0	-1.7
Angina (self-reported)	1.2	1.6	4.1	-1.0	-1.0	-1.5	-1.3	-1.4	-1.0	-1.7	-1.1	-1.7	-1.1	-1.2	-1.0	-1.6	-0.9	-1.0	-1.1	-0.9	-2.0	-0.7	-1.5	-0.1	-1.1	-1.3	-1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	2.5	1.4	1.4	1.6	1.2	1.0	1.4	0.1	1.2	0.5	0.5	1.5	1.4	1.6	1.4	1.4	1.0	0.9	1.1	1.1	1.0	0.2	1.4	1.4	0.2
Eye problems/disorders: Cataract	1.2	1.4	2.5	1.2	1.2	0.9	1.1	1.3	1.2	1.0	0.9	1.4	0.9	1.1	1.2	1.2	1.1	1.2	1.3	1.2	1.4	1.6	1.1	0.9	1.4	1.1	0.9
Frequency of depressed mood in last 2 weeks	1.1	1.5	3.1	-1.2	-1.2	-1.8	-1.2	-0.9	-1.2	-1.5	-0.9	-1.3	-1.1	-1.3	-1.2	-1.6	-1.2	-1.1	-1.6	-0.7	-0.6	-1.2	-1.3	-1.2	-1.2	-1.3	-1.5
Angina	1.1	1.4	4.6	-0.8	-0.9	-1.5	-1.2	-1.4	-0.8	-1.5	-0.9	-1.7	-1.0	-1.0	-0.8	-1.6	-0.7	-0.8	-1.0	-0.6	-2.1	-0.6	-1.5	0.2	-1.0	-1.1	-1.6
Medication: Ventolin 100micrograms inhaler	1.1	1.4	2.8	1.3	1.3	1.4	1.4	1.2	1.3	-0.4	0.8	1.4	-0.1	1.4	1.3	1.7	1.3	1.3	0.8	0.7	1.2	1.0	1.2	0.4	1.1	1.5	0.8
Mood swings	1.1	1.9	3.5	-1.2	-1.3	-1.6	-1.2	-1.4	-1.2	-1.8	-1.2	-1.2	-1.5	-1.3	-1.3	-1.9	-1.2	-1.2	-1.7	-1.0	-1.1	-1.2	-1.5	-1.3	-1.3	-1.4	-1.8
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	3.3	1.2	1.2	1.2	1.4	1.2	1.2	1.7	1.5	1.8	1.2	1.2	1.2	1.6	1.2	1.2	1.8	0.0	0.5	1.4	1.5	0.6	1.5	1.3	1.8
Breast cancer (self-reported)	1.1	1.3	2.7	-1.3	-1.3	-0.6	-1.1	-1.4	-1.3	-1.2	-1.1	0.3	-1.2	-1.1	-1.3	-1.1	-1.3	-1.3	-1.7	-0.9	0.1	-1.2	-1.1	-0.6	-1.3	-1.1	-1.1
Crohns Disease (2017)	1.0	2.1	10.3	1.5	1.6	1.6	1.4	0.6	1.5	-0.8	1.1	2.1	-1.2	1.6	1.7	1.7	1.7	1.4	1.0	0.8	3.2	1.1	0.8	0.9	1.1	1.2	0.6
Allergy or Eczema	1.0	2.5	22.1	0.9	1.0	1.9	1.2	1.9	0.9	0.6	0.9	3.5	0.5	1.1	0.9	1.6	0.9	0.8	1.3	0.1	4.7	0.9	1.2	-0.7	0.7	1.3	-0.8
Relative age of first facial hair	1.0	2.1	3.6	-1.4	-1.4	-1.4	-1.4	-1.2	-1.4	-1.1	-1.9	-1.2	-1.4	-1.5	-1.4	-1.3	-1.4	-1.4	-1.4	-1.6	0.1	-1.8	-1.4	-1.8	-1.5	-1.4	-1.5
Hair/balding pattern: Pattern 3	1.0	1.5	3.8	1.3	1.3	0.7	1.1	0.2	1.3	1.6	1.4	1.8	1.5	1.4	1.3	0.7	1.3	1.3	1.0	1.1	1.9	0.3	1.2	0.9	1.2	1.2	1.2
Noisy workplace	1.0	1.2	2.6	-1.1	-1.1	-1.5	-1.2	-1.5	-1.0	-0.7	-0.8	0.2	-0.6	-1.2	-1.1	-1.6	-1.0	-1.0	-1.3	-0.6	-0.4	-1.6	-1.2	-0.2	-1.0	-1.3	-1.3
Exposure to tobacco smoke at home	1.0	1.2	2.6	1.2	1.2	1.1	1.2	1.6	1.2	-0.7	0.6	1.4	-0.8	1.0	1.1	1.1	1.2	1.2	1.1	0.9	-0.8	1.2	0.8	1.0	1.1	1.1	1.1
Headache pain in last month	1.0	1.7	6.1	-1.4	-1.4	-1.3	-1.3	-0.4	-1.4	-0.5	-1.9	0.6	-0.8	-1.7	-1.4	-1.2	-1.4	-1.4	-0.9	-2.5	0.4	-1.8	-1.3	-0.1	-1.3	-1.5	-1.2
Comparative body size at age 10	1.0	2.8	6.6	1.8	1.8	1.1	1.7	0.8	1.8	1.4	1.8	-0.0	1.6	1.8	1.8	1.4	1.9	1.8	1.6	1.8	-1.2	1.4	1.8	2.6	1.9	1.6	2.0
Hypertension (Self-reported)	1.0	2.7	5.6	-1.9	-1.9	-1.5	-1.6	-1.9	-1.9	-0.4	-1.0	-1.1	-0.1	-1.8	-1.9	-1.8	-2.0	-1.9	-1.5	-1.8	-2.4	-1.2	-1.3	-1.6	-1.9	-1.8	-0.5
Friendships satisfaction	1.0	1.2	4.2	-1.0	-1.0	-1.0	-1.0	-0.6	-1.0	0.4	-0.6	-1.9	0.4	-1.0	-0.9	-1.1	-1.1	-1.0	-0.1	-2.0	-2.0	-0.8	-0.8	-1.7	-0.9	-0.7	-1.3
Hypothyroidism (self reported)	0.9	2.0	4.2	-1.6	-1.6	-1.9	-1.6	-1.2	-1.6	0.6	-0.5	-1.1	2.0	-1.6	-1.6	-1.4	-1.7	-1.6	-0.7	-0.7	-1.3	-2.0	-1.0	-1.4	-1.2	-1.5	-0.6
Qualifications: CSEs or equivalent	0.9	1.2	4.0	1.3	1.3	0.7	1.0	0.6	1.3	-0.6	0.9	0.8	-0.3	1.2	1.3	0.8	1.3	1.3	0.2	2.0	1.8	0.7	0.7	1.3	1.2	1.0	0.5
High blood pressure	0.9	2.4	5.6	-1.8	-1.8	-1.5	-1.6	-1.6	-1.8	-0.4	-1.0	-1.1	-0.1	-1.8	-1.8	-1.6	-1.9	-1.8	-1.4	-1.8	-2.4	-1.2	-1.3	-1.4	-1.8	-1.7	-0.5
Chronic bronchitis/emphysema (father)	0.9	1.0	1.7	-1.1	-1.1	-1.2	-1.2	-1.2	-1.0	0.8	-0.6	-1.2	0.9	-1.0	-1.0	-1.1	-1.1	-1.1	-0.7	-0.9	-1.3	-0.9	-0.9	-0.9	-0.9	-1.1	-0.4
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.5	0.8	0.8	1.2	1.1	1.0	0.8	1.2	1.5	0.3	1.4	0.9	0.8	1.2	0.7	0.8	1.3	0.6	0.9	0.8	1.3	0.7	0.9	1.1	1.6
Heart attack	0.9	1.2	3.2	-0.9	-1.0	-1.6	-1.1	-1.0	-0.9	-1.0	-1.1	-1.7	-0.6	-1.1	-1.0	-1.2	-1.0	-0.9	-0.9	-1.2	-1.8	-0.5	-1.0	-0.7	-0.9	-1.2	-0.7
Alcohol intake versus 10 years previously	0.9	1.3	4.7	-1.2	-1.2	-0.7	-0.8	-0.6	-1.3	-1.1	-0.9	-2.2	-0.9	-1.2	-1.2	-1.2	-1.3	-1.3	-1.0	-1.5	0.1	-0.3	-0.9	-1.1	-1.2	-1.1	-1.3
Body fat percentage	0.9	3.4	12.5	-1.8	-1.8	-2.1	-1.7	-2.0	-1.8	0.9	-0.9	-2.5	1.2	-1.8	-1.8	-2.0	-1.8	-1.8	-1.2	-2.3	-3.5	-1.3	-1.3	-2.1	-1.6	-2.0	-1.1
Neck or shoulder pain in last month	0.9	1.3	5.7	-1.3	-1.3	-1.2	-1.0	-0.3	-1.3	0.1	-1.5	0.4	-0.1	-1.4	-1.4	-0.9	-1.3	-1.3	-0.9	-2.4	-0.1	-1.3	-0.8	-0.2	-1.1	-1.2	-1.1
Ever had bowel cancer screening	0.9	1.0	2.4	-1.3	-1.3	-0.6	-0.9	-0.9	-1.3	0.1	-1.1	0.2	-0.4	-1.1	-1.3	-0.8	-1.3	-1.3	-1.1	-1.6	-0.5	-1.1	-0.7	-1.1	-1.2	-0.9	-0.1
Medication: Bendroflumethiazide	0.9	1.4	4.7	-1.2	-1.2	-1.1	-1.1	-1.6	-1.2	-0.4	-0.8	-0.6	-0.3	-1.0	-1.2	-1.2	-1.2	-1.2	-0.8	-1.5	-1.8	-1.1	-0.9	-2.2	-1.2	-1.2	-0.8
Neuroticism (Nagel 2018)	0.8	1.8	4.5	-1.0	-1.1	-1.6	-1.2	-0.5	-1.0	-2.1	-1.1	-1.7	-1.6	-1.4	-1.0	-1.7	-1.0	-1.0	-1.0	-1.0	-0.2	-1.5	-1.5	-1.8	-1.0	-1.3	-1.8
Lung FEV1/FVC ratio	0.8	4.2	16.6	-1.6	-1.7	-2.8	-2.3	-2.1	-1.6	0.8	-1.1	-3.5	1.1	-2.0	-1.6	-2.6	-1.6	-1.6	-1.2	-0.9	-4.1	-2.0	-1.7	-2.0	-1.4	-2.2	-2.3
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.4	0.9	1.0	1.1	1.0	1.3	0.9	0.3	0.8	0.3	0.3	1.0	1.0	1.6	1.0	0.9	1.0	0.5	0.0	1.4	0.8	1.0	0.9	1.1	1.1
Vitamin and mineral supplements	0.8	1.1	4.9	0.6	0.6	0.7	1.0	0.4	0.6	2.2	1.4	1.5	1.9	0.7	0.6	0.6	0.5	0.6	1.2	-0.8	1.1	1.3	1.3	0.0	0.8	0.7	1.0
Trunk fat percentage	0.8	3.1	10.2	-1.7	-1.7	-2.1	-1.6	-1.9	-1.7	0.8	-0.9	-2.4	1.1	-1.7	-1.7	-2.0	-1.7	-1.7	-1.1	-2.0	-3.2	-1.2	-1.2	-2.0	-1.5	-1.9	-1.2
High blood pressure (mother)	0.8	1.2	3.6	-1.2	-1.2	-1.3	-0.8	-1.5	-1.2	0.6	-0.3	-0.5	0.5	-1.1	-1.2	-1.4	-1.1	-1.2	-1.2	-0.8	-1.9	-1.2	-0.5	-0.8	-1.1	-1.2	-0.9
Pulse rate	0.8	1.3	2.5	1.3	1.3	0.8	0.9	0.9	1.3	0.9	0.9	0.2	1.2	1.3	1.3	1.0	1.2	1.3	1.5	1.6	-1.2	1.4	1.0	0.8	1.3	1.3	0.9
Depression (self-reported)	0.8	1.0	2.9	1.0	0.9	0.3	1.1	0.9	0.9	1.7	1.5	0.5	1.4	0.9	0.9	0.4	1.0	1.0	0.8	0.7	0.7	0.6	1.2	1.0	1.1	1.0	0.8
Prospective memory result	0.8	1.0	2.8	-1.0	-1.0	-1.2	-1.0	-0.3	-0.9	-1.6	-1.7	-0.3	-1.3	-1.1	-1.0	-1.0	-1.0	-1.0	-1.1	-1.2	-0.6	-1.1	-1.1	-0.1	-1.0	-0.9	0.2
Leg fat mass (right)	0.8	3.2	13.9	-1.7	-1.7	-2.2	-1.6	-2.0	-1.7	0.9	-0.6	-2.0	1.2	-1.7	-1.7	-2.1	-1.7	-1.7	-1.2	-2.2	-3.7	-1.4	-1.2	-1.8	-1.4	-1.9	-0.8
Medication: Aspirin	0.8	1.0	2.8	1.0	1.0	0.8	1.1	1.7	1.0	0.7	0.7	-0.1	0.8	0.8	1.0	0.9	0.9	1.0	1.2	0.5	0.3	1.4	1.0	1.4	1.0	1.0	1.4
Pain type(s) experienced in last month: Hip pain	0.8	1.0	4.8	0.9	0.8	0.7	1.1	0.5	0.9	1.0	1.6	2.2	1.3	1.1	0.8	0.5	0.8	0.8	1.1	0.7	-0.3	1.3	1.2	0.6	0.8	1.1	0.2
High cholesterol (Self-reported)	0.8	1.4	2.7	-1.4	-1.4	-1.5	-1.1	-1.4	-1.4	-0.1	-0.8	-1.6	0.3	-1.3	-1.4	-1.4	-1.4	-1.4	-1.4	-0.6	-1.1	-1.1	-0.9	-0.8	-1.2	-1.1	-0.8
Vascular/heart problems diagnosed by doctor	0.8	2.1	6.0	1.6	1.6	1.4	1.5	1.4	1.6	0.7	1.3	1.2	0.5	1.6	1.6	1.4	1.7	1.6	1.2	1.7	2.4	1.1	1.3	0.9	1.6	1.6	0.3
Cholesterol lowering medication	0.8	1.1	2.8	-0.9	-0.9	-1.7	-1.0	-1.2	-0.9	1.4	-0.0	-1.0	1.0	-1.1	-0.9	-1.5	-0.9	-0.9	-0.2	-1.2	-1.6	-1.0	-0.7	-1.1	-0.7	-1.0	-0.9
Leg fat mass (left)	0.8	3.1	13.5	-1.7	-1.7	-2.2	-1.6	-2.0	-1.7	0.9	-0.7	-2.1	1.3	-1.7	-1.7	-2.1	-1.8	-1.7	-1.1	-2.1	-3.7	-1.4	-1.2	-1.8	-1.4	-1.9	-0.6
Depression (Nagel 2018)	0.7	1.1	2.7	-1.0	-1.0	-1.3	-1.0	-0.8	-1.0	-1.0	-0.7	-0.9	-0.4	-1.2	-1.1	-1.5	-1.0	-1.0	-1.3	-0.4	-0.4	-1.2	-1.0	-0.7	-1.1	-1.1	-1.6
Coronary Artery Disease (CAD)	0.7	0.9	2.0	1.0	1.0	0.9	1.4	0.7	1.0	-0.1	1.1	0.6	0.6	1.1	1.1	0.9	1.1	1.0	0.9	0.7	1.0	0.9	1.4	0.8	0.8	1.1	0.1
Diabetes (father)	0.7	0.9	2.6	-0.7	-0.8	-1.6	-0.8	-1.2	-0.7	-0.9	-0.7	0.6	-0.7	-0.9	-0.7	-1.5	-0.7	-0.7	-1.1	-0.1	-1.4	-1.4	-1.0	0.1	-0.8	-1.0	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	2.1	-1.0	-1.0	-1.2	-0.8	-0.6	-1.0	-0.3	-0.6	-1.1	0.0	-1.1	-1.0	-1.4	-1.0	-1.0	-0.8	-1.1	-1.0	-1.2	-0.8	-0.5	-1.0	-1.1	-1.4
Hearing difficulty/problems with background noise	0.7	1.1	3.3	-0.8	-0.9	-1.8	-1.1	-1.0	-0.8	-1.0	-0.6	0.7	-0.6	-1.0	-0.8	-1.6	-0.8	-0.8	-1.0	-0.8	0.1	-1.5	-1.2	-0.7	-0.8	-1.0	-1.7
Medication: Paracetamol	0.7	1.2	2.4	1.2	1.2	1.4	1.3	0.8	1.2	0.1	1.2	-0.1	0.1	1.4	1.2	1.3	1.3	1.2	1.0	0.5	0.0	1.5	1.3	0.9	1.2	1.4	0.5
Chronic bronchitis/emphysema (mother)	0.7	0.8	2.7	-0.8	-0.8	-1.3	-0.9	-1.6	-0.8	0.5	-0.3	-0.4	0.9	-0.7	-0.7	-1.4	-0.8	-0.8	-0.8	-0.3	-1.4	-1.1	-0.7	0.0	-0.7	-1.0	-0.4
Medication: Seretide 50 evohaler	0.7	0.8	4.6	1.1	1.0	0.4	1.0	0.7	1.1	-0.5	0.5	2.1	-1.1	0.9	1.1	0.6	1.1	1.0	0.9	-0.7	0.9	0.2	0.5	0.6	0.6	0.7	0.2
Loneliness, isolation	0.7	1.0	5.3	-0.7	-0.8	-0.6	-0.5	-0.3	-0.7	-2.3	-1.1	-1.0	-1.7	-0.8	-0.7	-0.9	-0.8	-0.7	-0.7	-1.3	-1.2	-0.3	-0.7	-0.8	-0.9	-0.7	-1.0
Medication: Atorvastatin	0.7	0.8	3.5	0.7	0.7	0.4	0.9	0.9	0.7	1.3	0.9	0.1	1.6	0.6	0.7	0.4	0.6	0.7	0.6	1.0	-0.1	1.0	1.1	1.3	0.9	0.7	1.9
Rheumatoid Arthritis	0.6	0.8	4.9	0.2	0.1	0.2	0.5	0.5	0.1	1.7	0.9	1.3	2.0	0.1	0.2	0.5	0.3	0.1	0.7	0.7	1.0	0.1	0.8	0.4	0.5	0.3	2.2
Blood Eosinophil Count	0.6	4.4	53.3	0.6	0.7	1.1	1.1	1.0	0.6	0.0	0.3	6.2	-0.5	0.7	0.5	1.0	0.5	0.4	0.2	-0.3	7.3	1.1	1.0	-1.3	0.8	0.6	0.7
Severe depression (siblings)	0.6	0.7	2.0	-0.7	-0.7	-1.4	-0.8	-1.4	-0.7	1.3	0.2	-0.7	1.4	-0.6	-0.7	-1.0	-0.7	-0.7	-0.6	-0.0	-0.3	-0.7	-0.5	0.0	-0.5	-0.7	-1.0
Body mass index (BMI)	0.6	2.7	14.1	-1.4	-1.5	-2.2	-1.5	-2.1	-1.4	1.1	-0.5	-1.7	1.4	-1.5	-1.4	-2.1	-1.4	-1.4	-1.3	-1.7	-3.7	-1.4	-1.1	-1.0	-1.2	-1.7	-0.3
Trunk fat mass	0.6	2.8	9.3	-1.6	-1.7	-2.1	-1.6	-1.7	-1.7	0.9	-0.8	-2.1	1.1	-1.7	-1.7	-1.9	-1.7	-1.7	-1.0	-2.0	-3.0	-1.4	-1.1	-1.8	-1.4	-1.8	-0.8
Qualifications: None of the above	0.6	1.3	2.3	-1.0	-1.0	-1.1	-1.2	-0.9	-1.0	-1.2	-1.5	-1.1	-1.0	-1.3	-1.0	-1.2	-1.0	-1.0	-1.3	-0.3	-1.4	-1.5	-1.3	-0.2	-1.1	-1.2	-1.5
Medication: Ibuprofen	0.6	0.7	2.3	0.9	0.9	0.6	1.0	0.5	0.9	0.5	1.1	0.1	0.4	0.9	0.9	0.6	1.0	0.9	0.7	0.0	-0.1	1.1	0.8	1.5	0.9	0.9	-0.0
Whole body fat mass	0.6	2.7	10.4	-1.6	-1.6	-2.0	-1.4	-1.7	-1.6	1.1	-0.6	-2.0	1.4	-1.6	-1.6	-1.9	-1.6	-1.6	-0.9	-2.1	-3.2	-1.3	-1.0	-1.6	-1.3	-1.8	-0.6
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	3.1	-0.7	-0.7	-0.6	-0.9	-0.9	-0.7	0.0	-0.7	-1.1	0.1	-0.8	-0.7	-1.0	-0.7	-0.7	-0.2	-0.8	-1.1	-0.7	-0.7	-1.4	-0.8	-0.9	-1.8
Medication: Aspirin	0.6	0.8	2.2	0.9	0.9	0.8	1.0	1.5	0.9	0.7	0.8	0.0	0.9	0.7	0.9	0.9	0.7	0.9	1.0	0.5	0.5	1.3	0.9	1.1	0.9	0.9	1.2
Worry (Nagel 2018)	0.5	1.0	4.3	-0.6	-0.6	-1.1	-0.7	0.4	-0.6	-2.1	-0.8	-1.4	-1.8	-1.0	-0.6	-1.1	-0.5	-0.5	-0.6	-0.2	0.8	-1.0	-1.0	-1.0	-0.6	-0.8	-1.3
Alzheimer’s Disease (in mother)	0.5	0.6	3.7	0.6	0.6	0.0	0.4	-0.3	0.6	1.0	1.0	-0.7	1.1	0.8	0.5	0.0	0.7	0.6	0.4	1.1	-1.9	0.8	0.5	0.6	0.7	0.4	0.0
Alzheimer’s Disease (including proxy)	0.5	0.7	3.5	-0.8	-0.8	-1.1	-0.8	-1.2	-0.7	0.0	-0.2	-0.6	0.5	-0.5	-0.8	-1.1	-0.7	-0.7	-1.0	-0.1	-1.9	-0.7	-0.7	-0.4	-0.5	-0.8	-0.9
Blood Platelet Count	0.5	6.4	82.1	-0.9	-1.0	-1.4	-1.0	-2.4	-0.9	1.2	1.8	-2.8	3.2	-0.8	-1.8	-2.0	-0.7	-0.7	0.2	-2.9	-9.1	-1.5	-0.3	-3.2	-0.6	-1.2	-2.1
BMI	0.5	2.7	11.2	-1.6	-1.6	-1.9	-1.7	-1.7	-1.6	-0.3	-1.2	-2.0	-0.2	-1.7	-1.6	-1.9	-1.6	-1.6	-1.7	-1.7	-3.3	-1.4	-1.5	-0.7	-1.5	-1.8	-0.8
Lung FVC	0.5	2.3	5.7	1.8	1.8	1.4	1.5	1.2	1.8	0.4	1.3	0.5	0.5	1.8	1.8	1.6	1.9	1.9	1.1	2.3	0.4	1.0	1.3	2.4	1.7	1.7	0.7
Townsend deprivation index at recruitment	0.5	0.7	2.3	-0.7	-0.7	-0.8	-0.7	-1.2	-0.7	-1.0	-0.3	-0.6	-0.2	-0.7	-0.7	-0.8	-0.7	-0.7	-1.5	0.6	-1.2	-0.7	-0.7	-0.7	-0.6	-0.9	-1.2
Medication: Levothyroxine sodium	0.5	0.8	2.9	-0.8	-0.9	-1.5	-1.0	-0.8	-0.8	0.7	-0.5	-1.4	1.7	-0.9	-0.9	-1.0	-0.9	-0.8	-0.5	0.3	-0.9	-1.2	-0.6	-0.2	-0.4	-0.9	-0.0
Father’s age at death	0.5	0.7	2.7	-0.9	-0.9	0.1	-0.6	0.7	-0.9	-0.0	-1.1	-1.6	0.1	-1.1	-0.9	0.1	-0.9	-0.9	-0.3	-1.3	-0.4	-1.0	-0.4	-0.6	-1.0	-0.7	0.1
Happiness	0.5	0.6	1.4	-0.7	-0.8	-1.2	-0.9	-0.7	-0.7	-0.3	-0.6	-0.7	0.2	-0.8	-0.7	-1.0	-0.9	-0.7	-0.8	-0.9	-0.4	-0.8	-0.7	-0.8	-0.6	-0.8	-1.2
Breastfed as a baby	0.5	0.6	2.2	0.5	0.5	1.4	0.5	1.3	0.5	-0.6	-0.1	0.9	-1.0	0.5	0.5	1.3	0.6	0.5	0.2	0.9	1.5	0.5	0.4	0.5	0.3	0.7	-0.0
Glaucoma (self-reported)	0.5	0.6	1.4	0.8	0.8	0.7	0.7	0.2	0.8	0.7	1.1	1.1	1.2	0.7	0.8	0.7	0.6	0.8	0.9	0.9	0.2	0.9	0.8	0.3	1.0	0.7	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	2.2	-0.8	-0.8	-0.7	-0.7	-0.5	-0.8	0.0	-0.3	-1.5	0.2	-0.9	-0.8	-0.8	-0.8	-0.8	-0.6	-0.6	-1.4	-0.6	-0.6	-0.9	-0.6	-0.8	-0.9
Shortness of breath walking on level ground	0.5	0.6	3.0	-1.0	-1.0	-0.4	-0.6	-0.7	-1.0	-0.1	0.2	-0.0	0.1	-0.7	-1.0	-0.2	-1.0	-1.0	-0.8	-0.1	-1.7	-0.9	-0.5	-0.7	-1.0	-0.5	0.8
Chest pain or discomfort	0.5	0.6	2.6	-0.7	-0.8	-1.1	-1.0	-0.5	-0.7	-0.3	-0.4	0.2	-0.1	-0.8	-0.7	-1.2	-0.8	-0.7	-0.5	-1.6	-0.9	-0.8	-0.8	-0.1	-0.7	-0.9	-1.1
Diabetes diagnosed by doctor	0.5	0.8	2.0	0.7	0.7	1.0	0.8	0.3	0.7	1.1	0.9	0.2	1.3	1.0	0.8	0.9	0.8	0.7	0.9	1.0	-1.0	1.4	0.8	0.3	0.9	0.9	1.1
Mineral and other dietary supplements	0.5	0.7	2.6	0.7	0.7	0.5	0.7	0.4	0.7	1.4	0.8	0.8	1.6	0.7	0.7	0.5	0.6	0.7	0.8	0.5	1.6	0.8	0.7	0.3	1.0	0.6	1.0
Financial situation satisfaction	0.5	0.6	1.8	-0.7	-0.7	-0.8	-0.9	-1.2	-0.7	-0.4	-0.4	-1.4	-0.1	-0.6	-0.7	-0.9	-0.7	-0.7	-1.0	-0.4	0.4	-0.9	-0.7	-1.0	-0.5	-0.8	-0.9
Tinnitus: Yes, now most or all of the time	0.5	0.5	1.4	-0.7	-0.7	-1.2	-0.9	0.3	-0.7	-1.0	-1.1	-0.8	-0.5	-1.0	-0.7	-0.7	-0.6	-0.7	-0.7	0.1	-0.1	-0.7	-0.9	0.8	-0.6	-0.7	-0.2
Basal cell carcinoma (self-reported)	0.5	0.5	2.3	0.8	0.7	0.2	0.7	1.5	0.8	0.2	0.2	0.5	0.5	0.4	0.7	0.7	0.7	0.8	1.1	0.4	-0.9	0.4	0.8	0.4	0.7	0.8	1.2
Schizophrenia (2018)	0.4	0.9	1.8	-0.9	-0.9	-1.2	-1.2	-1.3	-0.9	0.5	-0.1	-0.7	0.5	-0.9	-0.9	-1.3	-0.7	-0.9	-0.8	-1.1	-1.0	-1.3	-1.0	-1.1	-0.8	-0.9	-0.6
Major Depression (MDD)	0.4	0.5	3.1	0.7	0.6	-0.6	0.5	0.6	0.7	0.3	0.6	-0.9	0.4	0.3	0.7	-0.2	0.8	0.7	0.7	0.9	-1.8	-0.1	0.3	0.6	0.7	0.5	0.5
Fasting Glucose	0.4	0.5	2.1	-0.3	-0.4	-1.4	-0.9	-1.4	-0.3	-0.2	-0.4	-0.2	-0.3	-0.5	-0.3	-1.1	-0.3	-0.3	-0.8	0.5	-0.3	-0.5	-0.5	-0.6	-0.5	-0.6	-1.4
Average weekly fortified wine intake	0.4	0.4	2.9	0.1	0.1	0.7	0.5	1.1	0.1	-0.6	-0.1	1.2	-0.0	0.1	0.0	0.7	0.0	0.1	0.1	-0.1	1.7	0.4	0.5	1.2	0.1	0.4	0.9
Medication: Atenolol	0.4	0.5	2.5	-0.6	-0.6	-0.6	-0.6	-1.4	-0.6	-0.7	-0.5	-0.9	-0.1	-0.4	-0.5	-0.7	-0.6	-0.6	-1.3	-0.2	-1.6	-0.3	-0.6	-0.7	-0.5	-0.6	-0.3
Alcohol usually taken with meals	0.4	0.6	5.9	-0.1	-0.1	0.7	0.0	0.9	-0.1	0.2	-0.8	2.4	-0.4	-0.0	-0.1	0.5	-0.1	-0.2	0.3	-0.8	1.8	0.4	0.2	1.1	-0.2	0.2	0.0
Weight	0.4	2.0	7.8	-1.4	-1.5	-1.9	-1.2	-1.5	-1.4	1.1	-0.4	-1.3	1.2	-1.4	-1.4	-1.8	-1.4	-1.4	-0.8	-1.9	-2.8	-1.4	-0.9	-1.1	-1.1	-1.5	-0.1
Impedance of arm (right)	0.4	1.6	9.7	1.1	1.2	1.7	1.2	1.8	1.1	-0.1	0.4	0.6	-0.5	1.1	1.1	1.6	1.1	1.1	1.4	0.6	3.1	1.7	1.0	-0.2	1.0	1.3	-0.5
Falls in the last year	0.4	0.6	1.5	0.8	0.8	0.9	0.8	0.8	0.8	-1.2	-0.1	0.8	-0.9	0.8	0.7	0.8	0.8	0.8	0.2	0.7	1.1	0.6	0.5	1.1	0.5	0.9	0.6
Qualifications: A levels/AS levels or equivalent	0.4	0.9	2.7	0.9	0.9	1.1	1.2	1.2	0.9	0.2	0.5	0.1	0.2	1.1	0.9	1.1	0.9	0.9	1.0	0.9	1.6	1.4	1.1	0.2	0.9	1.2	0.6
Illnesses of mother	0.4	0.5	4.0	-0.1	-0.0	0.2	-0.3	0.7	-0.1	-1.5	-1.1	-0.3	-2.0	-0.3	-0.1	0.4	-0.0	-0.1	-0.0	-0.7	1.0	0.3	-0.6	-0.1	-0.2	-0.0	-0.6
Pulse wave reflection index	0.4	0.5	3.2	-0.7	-0.7	-0.4	-0.8	-0.4	-0.7	0.7	0.1	-0.2	0.9	-0.8	-0.7	-0.8	-0.7	-0.8	-0.4	-0.7	1.8	-0.6	-0.5	-0.7	-0.5	-0.6	-0.8
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	2.7	-0.6	-0.6	-0.7	-0.7	-0.6	-0.6	-1.0	-0.9	0.3	-1.6	-0.7	-0.6	-0.6	-0.5	-0.6	-0.5	-0.6	0.5	-1.0	-0.9	-0.7	-0.7	-0.7	-1.2
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	4.7	-1.1	-1.1	-1.1	-0.8	-0.6	-1.1	0.9	-0.3	-0.6	2.2	-1.0	-1.1	-0.7	-1.2	-1.0	-0.3	0.1	-0.2	-1.0	-0.3	-0.4	-0.6	-0.8	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	5.6	0.4	0.4	0.1	0.5	0.0	0.4	0.4	0.8	0.7	0.3	0.5	0.4	0.2	0.4	0.4	0.5	1.1	2.4	0.0	0.4	1.1	0.3	0.3	0.2
Age at first live birth	0.4	0.7	3.0	-0.2	-0.2	0.0	-0.3	0.6	-0.1	-1.7	-1.0	1.0	-1.7	-0.4	-0.1	-0.1	-0.4	-0.2	-0.3	-1.2	1.7	-0.4	-0.6	-1.1	-0.3	-0.4	-1.0
Medication for pain relief, constipation, heartburn	0.4	0.7	2.0	-0.8	-0.8	-0.6	-1.0	-0.3	-0.8	-0.6	-1.0	0.9	-0.7	-0.8	-0.8	-0.6	-0.9	-0.8	-0.7	-0.1	0.7	-1.1	-0.9	-1.4	-0.9	-0.8	-0.6
Comparative height size at age 10	0.4	2.3	4.4	1.6	1.6	1.4	1.6	1.8	1.6	0.8	1.4	2.0	0.2	1.6	1.5	1.5	1.6	1.5	2.1	1.0	0.9	1.4	1.4	1.8	1.6	1.7	1.2
Number of full sisters	0.4	0.4	2.1	0.6	0.6	0.6	0.3	-0.1	0.6	1.2	1.2	0.1	1.4	0.7	0.6	0.6	0.5	0.6	0.7	0.7	-0.5	0.4	0.4	0.3	0.7	0.5	0.4
Family relationship satisfaction	0.4	0.5	2.2	-0.7	-0.7	-0.5	-0.6	-0.1	-0.7	0.4	-0.5	-1.5	0.5	-0.7	-0.6	-0.6	-0.7	-0.6	0.1	-1.5	-0.7	-0.5	-0.4	-0.5	-0.5	-0.5	-0.8
Arm fat percentage (left)	0.4	1.6	6.9	-1.1	-1.1	-1.7	-1.2	-1.3	-1.1	0.8	-0.5	-1.9	0.9	-1.3	-1.1	-1.6	-1.1	-1.1	-0.8	-1.5	-2.6	-0.8	-0.9	-1.1	-0.9	-1.5	-0.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	0.9	-0.7	-0.8	-0.9	-0.4	-0.9	-0.8	-0.1	-0.5	-0.7	-0.4	-0.6	-0.7	-0.7	-0.7	-0.7	-0.9	-0.2	-0.6	-0.9	-0.4	-0.9	-0.7	-0.7	-1.0
Arm fat mass (left)	0.4	1.7	8.4	-1.2	-1.2	-1.9	-1.2	-1.4	-1.2	1.0	-0.4	-1.4	1.2	-1.3	-1.2	-1.7	-1.2	-1.2	-0.8	-1.5	-2.9	-1.1	-0.8	-1.0	-1.0	-1.5	-0.2
Medication: Blood pressure	0.4	0.8	6.4	-0.9	-0.8	-0.7	-0.7	-0.9	-0.9	0.1	-0.5	-0.0	-0.1	-0.8	-0.9	-0.6	-0.9	-0.9	-0.2	-1.2	-2.5	-0.7	-0.6	-0.8	-0.9	-0.8	0.1
Medication: Paracetamol	0.4	0.6	1.1	0.9	0.9	1.1	0.9	0.6	0.9	-0.6	0.8	0.2	-0.4	1.0	0.9	1.0	1.0	0.9	0.8	0.2	0.1	1.1	0.8	0.4	0.8	1.0	0.3
Illnesses of father: High blood pressure	0.4	0.5	1.0	-0.8	-0.8	-0.9	-0.7	-0.5	-0.8	0.6	-0.6	-1.0	0.4	-0.8	-0.8	-0.9	-0.9	-0.8	-0.3	-0.6	-0.9	-0.7	-0.6	-0.6	-0.6	-0.7	-0.2
Alcohol drinker status: Never	0.4	0.5	1.4	-0.7	-0.7	-1.2	-0.7	-0.5	-0.7	-0.6	0.0	0.2	-0.0	-0.8	-0.7	-1.0	-0.7	-0.7	-0.3	-0.4	-1.1	-0.8	-0.5	-1.0	-0.7	-0.7	-0.1
Ever had prostate specific antigen (PSA) test	0.4	0.4	3.9	0.4	0.4	-0.3	0.1	-0.3	0.4	1.0	-0.1	-2.0	1.0	0.3	0.4	-0.3	0.5	0.4	0.8	0.4	-1.3	0.3	0.3	-0.1	0.7	0.1	0.4
Diastolic blood pressure, automated reading	0.4	1.3	4.3	-1.3	-1.3	-0.9	-0.9	-1.3	-1.3	1.1	-0.7	-0.6	0.7	-1.1	-1.3	-1.2	-1.2	-1.3	-0.7	-2.1	-1.2	-0.6	-0.7	-0.9	-1.2	-1.2	-0.7
Supplements: Calcium	0.4	0.4	2.3	0.3	0.4	0.6	0.4	1.5	0.3	0.8	0.4	1.3	1.0	0.3	0.4	0.6	0.3	0.4	0.4	0.6	-0.3	0.3	0.5	0.6	0.5	0.6	0.9
Alcohol drinker status: Previous	0.4	0.4	1.9	-0.6	-0.6	0.1	-0.2	-0.8	-0.6	-1.0	-0.6	-0.7	-1.4	-0.3	-0.6	0.3	-0.5	-0.6	-1.3	-0.4	-0.1	-0.3	-0.4	-0.3	-0.9	-0.3	-0.8
Bipolar Disorder or Schizophrenia	0.3	0.7	2.5	-0.7	-0.8	-1.3	-0.9	-1.6	-0.7	0.2	-0.3	-0.2	-0.0	-0.8	-0.8	-1.4	-0.6	-0.7	-0.7	-1.2	-1.0	-1.0	-0.8	-0.9	-0.7	-1.0	-0.7
Heel T-Score	0.3	2.1	4.6	-1.5	-1.5	-1.1	-1.6	-2.0	-1.5	-0.3	-1.2	-0.5	0.2	-1.3	-1.6	-1.4	-1.4	-1.4	-2.1	-1.3	-2.1	-1.9	-1.5	-1.4	-1.4	-1.8	-0.9
Sensitivity / hurt feelings	0.3	0.4	1.7	-0.5	-0.5	-0.8	-0.4	-0.3	-0.5	-0.8	-0.3	-1.3	-0.8	-0.7	-0.5	-1.0	-0.5	-0.5	-0.3	-1.2	-0.2	-0.3	-0.5	-0.7	-0.5	-0.5	-1.0
Systolic blood pressure, automated reading	0.3	1.0	2.5	-1.2	-1.2	-1.0	-1.0	-1.0	-1.2	0.4	-0.5	0.5	0.4	-1.2	-1.2	-1.2	-1.2	-1.2	-0.7	-1.6	-0.3	-0.9	-0.7	-1.3	-1.2	-1.0	-0.7
Medication for hormone replacement therapy	0.3	0.3	5.1	-0.1	-0.1	0.4	0.1	0.3	-0.1	-0.1	-0.1	1.2	-0.0	0.0	-0.1	0.5	-0.1	-0.1	0.0	-0.6	2.3	-0.2	0.0	0.0	-0.0	0.2	-0.3
Current tobacco smoking	0.3	0.6	1.5	-0.8	-0.8	-0.6	-0.7	-0.9	-0.8	1.0	0.1	-1.1	1.2	-0.7	-0.8	-0.7	-0.8	-0.8	-0.6	-0.3	-1.2	-0.5	-0.4	-0.6	-0.6	-0.6	0.2
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.8	-0.4	-0.4	-0.3	-0.3	-0.2	-0.4	-0.1	0.0	-0.8	0.1	-0.3	-0.4	-0.4	-0.4	-0.4	-0.4	-0.2	1.4	-0.6	-0.2	-1.2	-0.3	-0.3	-0.9
Serious illness, injury or assault to yourself	0.3	0.4	1.4	-0.6	-0.6	-0.8	-0.6	-0.8	-0.6	-0.4	-0.6	-1.0	-0.6	-0.5	-0.6	-0.7	-0.6	-0.5	-1.2	-0.5	0.1	-0.2	-0.5	0.6	-0.5	-0.6	0.1
Supplements: Glucosamine	0.3	0.4	3.7	-0.2	-0.2	-0.9	-0.3	-0.6	-0.2	-0.5	-0.3	-1.3	-0.6	-0.2	-0.2	-0.7	-0.2	-0.2	-0.3	-0.1	-1.9	-0.4	-0.4	-0.7	-0.2	-0.2	-1.1
Waist circumference	0.3	1.0	6.0	-0.6	-0.7	-1.1	-0.5	-1.0	-0.6	1.4	0.5	-0.8	1.9	-0.6	-0.7	-1.0	-0.7	-0.6	-0.2	-1.4	-2.5	-0.3	-0.1	-1.3	-0.4	-0.8	-0.4
Nervous feelings	0.3	0.6	3.5	0.7	0.7	0.1	0.3	1.3	0.7	-1.6	0.2	0.1	-1.2	0.3	0.6	0.3	0.6	0.7	0.7	0.5	1.9	0.1	0.2	-0.6	0.7	0.3	-0.2
Hair/balding pattern: Pattern 2	0.3	0.4	1.2	0.7	0.7	-0.1	0.7	0.2	0.7	-0.3	0.2	-0.1	-0.1	0.6	0.7	0.1	0.7	0.7	0.6	1.1	-0.7	1.0	0.4	0.7	0.8	0.5	-0.2
Pain all over the body in last month	0.3	0.3	2.2	-0.1	-0.1	-1.1	-0.4	-0.6	-0.1	0.8	0.4	-1.5	0.9	-0.3	-0.1	-0.8	0.0	-0.1	0.2	0.1	0.6	-0.4	-0.1	0.4	0.2	-0.5	-0.8
Diabetes (self-reported)	0.3	0.5	3.8	0.5	0.5	0.4	0.5	0.1	0.5	0.7	0.5	-0.3	0.9	0.7	0.6	0.5	0.5	0.6	0.8	0.6	-1.9	1.0	0.5	0.0	0.6	0.6	0.7
Medication: Ramipril	0.3	0.3	2.2	-0.2	-0.2	0.4	0.1	0.6	-0.2	1.3	-0.1	1.5	1.2	-0.1	-0.2	0.3	-0.3	-0.2	0.5	-0.6	-0.5	0.2	0.5	0.2	-0.2	0.2	1.0
Hip circumference	0.3	1.1	8.5	-0.7	-0.8	-1.0	-0.3	-0.9	-0.8	1.8	0.3	-0.8	1.8	-0.6	-0.8	-1.0	-0.8	-0.8	-0.2	-1.4	-2.9	-0.4	0.0	-0.8	-0.5	-0.7	0.1
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	3.1	-0.1	-0.1	-0.5	-0.0	0.2	-0.1	-1.8	-0.2	1.3	-1.7	-0.2	-0.1	-0.3	-0.1	-0.1	-0.7	0.3	-0.2	-0.5	-0.5	0.5	-0.4	-0.3	0.1
Medication: Cholesterol lowering	0.3	0.5	2.2	0.4	0.4	0.5	0.5	0.6	0.4	0.4	0.4	-0.8	1.0	0.6	0.4	0.4	0.4	0.5	0.3	0.9	-0.4	1.0	0.6	1.3	0.5	0.6	1.5
Arm fat mass (right)	0.3	1.4	8.3	-0.9	-1.0	-1.7	-0.9	-1.3	-0.9	1.1	-0.1	-1.3	1.4	-1.0	-0.9	-1.5	-0.9	-0.9	-0.6	-1.2	-2.9	-0.8	-0.6	-0.8	-0.7	-1.2	-0.2
Tense / ‘highly strung’	0.3	0.5	5.2	0.3	0.3	0.6	0.6	1.6	0.3	-0.1	0.1	0.6	0.1	0.2	0.3	0.6	0.4	0.3	0.4	-0.3	2.3	0.6	0.6	0.8	0.4	0.5	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.9	-0.7	-0.7	-0.7	-0.6	-0.5	-0.7	-0.4	-0.3	-0.9	-0.2	-0.6	-0.7	-0.9	-0.6	-0.7	-0.8	0.1	-1.0	-0.7	-0.5	0.3	-0.7	-0.7	-0.4
Health satisfaction	0.3	0.4	4.4	-0.3	-0.3	-0.9	-0.5	-0.5	-0.3	0.1	-0.1	-1.5	0.7	-0.3	-0.2	-0.5	-0.3	-0.2	-0.1	-0.1	-2.1	-0.1	-0.4	0.6	-0.3	-0.4	-0.3
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.5	0.4	0.4	-1.2	-0.0	-0.4	0.5	1.1	0.7	0.2	1.2	0.3	0.5	-0.8	0.4	0.4	0.6	-0.2	-0.1	-0.0	-0.0	1.1	0.6	-0.0	0.4
Medication: Allopurinol	0.3	0.4	1.7	0.4	0.3	-0.7	0.1	-0.0	0.5	1.0	0.5	-1.1	1.3	0.3	0.4	-0.4	0.5	0.4	-0.0	1.0	-0.9	0.3	0.2	0.2	0.7	0.1	0.6
Pulse rate, automated reading	0.3	1.0	1.8	1.2	1.2	0.5	1.0	1.0	1.3	0.7	0.9	0.7	0.8	1.2	1.3	0.8	1.2	1.3	1.3	0.8	-0.1	1.1	1.0	0.6	1.2	1.2	0.3
Suffer from ‘nerves’	0.3	0.4	0.9	0.8	0.8	0.2	0.6	0.7	0.8	-0.3	0.9	-0.5	0.0	0.6	0.8	0.4	0.9	0.9	0.7	0.5	0.9	0.4	0.5	-0.2	0.9	0.5	0.1
Overall health rating	0.3	0.7	1.2	-1.0	-1.0	-0.9	-0.8	-0.7	-1.0	0.2	0.1	1.0	1.0	-0.9	-1.0	-0.9	-1.1	-1.0	-0.6	-1.0	-0.8	-0.8	-0.5	-0.4	-0.8	-0.8	0.0
Illnesses of father: Heart disease	0.3	0.4	2.4	-0.4	-0.4	-0.8	-0.5	-1.4	-0.4	0.1	-0.2	-0.2	-0.2	-0.2	-0.4	-0.8	-0.3	-0.4	-0.8	-0.2	-1.5	-0.2	-0.5	-0.3	-0.5	-0.6	-0.8
Smoking status: Current	0.3	0.5	1.9	-0.8	-0.8	-0.6	-0.7	-0.8	-0.8	0.8	0.1	-1.2	1.1	-0.7	-0.8	-0.7	-0.8	-0.8	-0.7	-0.1	-1.4	-0.6	-0.4	-0.5	-0.6	-0.5	0.2
Eye problems/disorders: Glaucoma	0.3	0.4	1.2	0.5	0.5	0.4	0.6	-0.4	0.5	0.7	0.9	0.1	0.9	0.5	0.6	0.4	0.4	0.6	0.6	0.2	-1.1	0.8	0.6	0.1	0.7	0.4	0.2
Supplements: Fish oil (including cod liver oil)	0.3	0.4	2.1	-0.5	-0.5	-0.2	-0.5	-0.1	-0.5	-1.0	-0.8	-1.0	-1.1	-0.6	-0.6	-0.2	-0.5	-0.5	-0.6	-0.2	-1.4	-0.9	-0.6	0.0	-0.6	-0.5	-0.3
Risk taking	0.3	0.5	3.5	0.3	0.3	0.0	0.3	-0.0	0.3	1.9	0.3	0.8	1.6	0.3	0.3	0.2	0.3	0.4	0.3	0.5	-0.7	0.2	0.7	1.2	0.7	0.2	1.1
Unable to work because of sickness or disability	0.3	0.4	5.5	-0.1	-0.1	0.5	0.3	-0.2	-0.1	-1.0	0.6	0.9	-0.3	0.3	-0.1	0.4	-0.1	-0.1	-0.5	0.3	2.3	0.3	0.2	-0.1	-0.1	0.2	-0.2
Heart disease (siblings)	0.3	0.3	0.8	-0.6	-0.6	-0.7	-0.6	-0.9	-0.6	-0.8	-0.3	-0.7	-0.2	-0.6	-0.5	-0.9	-0.6	-0.6	-0.7	-0.1	-0.1	-0.4	-0.6	0.1	-0.6	-0.7	-0.2
Schizophrenia vs Biploar Disorder	0.2	0.3	0.9	0.4	0.4	0.0	0.2	0.4	0.4	0.8	0.4	-0.9	0.9	0.4	0.5	0.3	0.5	0.4	0.9	0.3	-0.4	0.4	0.3	0.6	0.5	0.5	0.3
Breast Cancer	0.2	0.6	4.8	0.3	0.3	0.3	0.3	1.0	0.3	-1.0	-0.4	-0.2	-1.4	0.1	0.3	0.5	0.3	0.3	0.1	0.8	2.2	0.3	0.0	-1.1	0.2	0.3	-1.2
Mean Putamen Volume	0.2	0.2	0.9	0.1	0.1	0.4	0.0	0.2	0.1	-0.5	-0.2	0.8	-0.8	0.1	0.1	0.3	0.1	0.1	-0.2	-0.4	-0.9	0.2	-0.1	-0.9	-0.1	0.2	-0.4
HbA1C	0.2	0.2	1.5	0.3	0.3	0.4	0.4	0.2	0.3	-0.9	-0.1	-0.2	-0.4	0.3	0.3	0.3	0.3	0.3	-0.1	0.4	-0.4	0.4	0.3	1.2	0.1	0.3	-0.6
HDL Cholesterol	0.2	0.4	1.4	0.4	0.4	1.2	0.6	0.9	0.4	0.2	0.6	0.3	0.1	0.4	0.3	0.9	0.2	0.3	0.5	0.1	1.0	1.0	0.5	-0.2	0.6	0.6	1.2
Blood Red Count	0.2	1.4	15.4	0.3	0.3	0.5	0.7	1.2	0.3	1.5	1.0	3.9	1.2	0.4	-0.3	0.2	0.2	0.2	1.2	-1.5	1.4	0.7	0.9	-1.9	0.4	0.5	-0.8
Systolic Blood Pressure	0.2	1.0	3.1	-1.2	-1.2	-1.2	-1.0	-1.2	-1.2	0.5	-0.4	0.0	0.0	-1.1	-1.2	-1.2	-1.2	-1.2	-0.8	-1.8	-0.2	-0.9	-0.9	-1.2	-1.1	-1.1	-0.7
Smoking Status	0.2	0.4	1.8	-0.6	-0.6	-0.6	-0.5	-0.4	-0.6	1.0	-0.4	-1.3	0.8	-0.7	-0.6	-0.3	-0.5	-0.5	-0.4	-0.7	-1.3	-0.6	-0.4	0.2	-0.4	-0.6	-0.4
Type 2 Diabetes (T2D) (2018)	0.2	0.5	1.5	0.5	0.5	0.9	0.6	0.5	0.5	0.6	0.3	-0.0	0.7	0.7	0.5	1.1	0.5	0.5	0.6	0.7	-0.8	1.1	0.6	0.1	0.6	0.8	1.2
Neuroticism	0.2	0.6	3.0	-0.3	-0.4	-1.3	-0.7	0.0	-0.3	-1.3	-0.4	-1.7	-0.7	-0.7	-0.3	-1.1	-0.3	-0.3	-0.3	-0.5	-0.1	-0.7	-0.8	-0.5	-0.2	-0.7	-1.3
Chronotype (morning person)	0.2	0.5	1.6	-0.6	-0.6	-0.9	-1.0	-0.9	-0.6	0.0	-0.5	-1.3	0.2	-0.7	-0.7	-0.7	-0.7	-0.6	-0.3	0.3	-0.3	-1.0	-0.8	-0.3	-0.6	-0.8	-0.3
Hand grip strength (left)	0.2	0.4	2.6	0.5	0.5	0.2	0.3	0.7	0.5	0.4	0.2	1.6	0.2	0.3	0.5	0.3	0.6	0.5	0.4	0.5	1.3	-0.2	0.2	1.4	0.5	0.3	0.6
Number of treatments/medications taken	0.2	0.4	1.5	0.5	0.6	0.7	0.9	0.6	0.5	0.2	0.9	0.6	0.8	0.7	0.5	0.7	0.5	0.6	0.6	0.1	1.2	0.6	0.8	0.4	0.5	0.8	0.8
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.1	-0.6	-0.5	-0.3	-0.3	0.1	-0.6	0.7	-0.1	0.6	0.4	-0.5	-0.6	-0.1	-0.6	-0.6	-0.0	-1.0	0.9	-0.0	-0.0	-0.8	-0.3	-0.2	0.3
Ever had hysterectomy (womb removed)	0.2	0.2	1.3	0.1	0.1	0.3	0.3	-0.2	0.1	0.8	0.2	0.3	1.0	0.3	0.1	0.7	0.1	0.1	0.1	0.6	-1.1	0.1	0.4	-0.1	0.3	0.2	1.1
Supplements: Zinc	0.2	0.2	0.9	-0.1	-0.1	-0.3	-0.5	0.3	-0.1	-0.8	-0.3	-0.6	-0.8	-0.3	-0.1	-0.1	-0.1	-0.1	-0.3	0.5	0.6	-1.0	-0.5	-0.7	-0.1	-0.3	-0.6
Medication: Co-codamol	0.2	0.2	3.2	-0.0	-0.0	0.2	0.2	-0.4	-0.0	0.4	0.5	-0.4	1.0	0.3	-0.1	0.3	-0.1	-0.0	0.0	0.1	-1.8	0.5	0.4	0.0	0.1	0.1	0.0
Medication: Metformin	0.2	0.3	1.0	0.4	0.4	0.4	0.2	0.3	0.4	0.7	0.7	0.5	0.8	0.5	0.4	0.4	0.4	0.4	0.8	0.3	-1.0	0.6	0.1	-0.0	0.4	0.5	0.6
Leg fat-free mass (left)	0.2	0.9	2.1	-1.1	-1.1	-1.3	-0.8	-1.0	-1.1	0.1	-0.4	-0.5	-0.1	-1.0	-1.1	-1.4	-1.1	-1.1	-0.7	-1.3	-1.4	-1.1	-0.8	-0.5	-0.9	-1.0	0.4
Hand grip strength (right)	0.2	0.5	3.1	0.5	0.5	0.7	0.4	0.5	0.5	0.6	0.5	1.8	0.4	0.6	0.5	0.6	0.6	0.5	0.7	0.7	0.7	-0.0	0.4	1.4	0.5	0.6	0.9
Maternal smoking around birth	0.2	0.2	2.1	0.3	0.2	-0.3	-0.2	0.0	0.3	0.9	-0.3	0.6	0.5	-0.0	0.3	-0.3	0.3	0.3	0.5	0.2	-1.4	-0.2	0.0	1.1	0.3	-0.1	-0.2
Stomach or abdominal pain in last month	0.2	0.2	0.8	-0.4	-0.4	-0.1	-0.2	-0.7	-0.4	-0.2	-0.5	-0.9	-0.5	-0.4	-0.4	-0.2	-0.4	-0.4	-0.6	-0.7	-0.6	0.1	-0.2	-0.1	-0.5	-0.4	-0.5
Leg predicted mass (left)	0.2	0.8	2.0	-1.0	-1.1	-1.3	-0.8	-0.9	-1.0	0.1	-0.4	-0.4	-0.1	-1.0	-1.0	-1.4	-1.0	-1.0	-0.7	-1.2	-1.4	-1.1	-0.7	-0.4	-0.8	-1.0	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	2.0	-0.1	-0.2	-0.4	-0.3	0.7	-0.1	-1.4	-0.6	-0.3	-1.1	-0.4	-0.2	-0.5	-0.1	-0.1	-0.4	-0.6	0.9	-0.6	-0.5	0.4	-0.1	-0.3	-0.6
Had other major operations	0.2	0.2	1.3	-0.2	-0.3	-0.5	-0.2	-1.2	-0.2	1.0	0.4	-0.7	0.7	-0.0	-0.2	-0.1	-0.2	-0.2	-0.4	-0.3	-0.1	-0.5	-0.2	0.7	-0.2	-0.1	-0.3
Forced vital capacity (FVC)	0.2	0.6	1.3	0.6	0.6	1.1	1.0	0.7	0.6	0.5	0.6	1.0	0.0	0.9	0.5	1.0	0.7	0.6	0.8	1.0	1.0	0.9	0.9	1.0	0.6	1.0	0.3
Medication: Simvastatin	0.2	0.3	1.5	-0.4	-0.4	-0.6	-0.4	-0.3	-0.4	1.0	0.1	-1.2	1.0	-0.4	-0.4	-0.5	-0.4	-0.4	0.0	-0.7	-0.9	-0.5	-0.2	0.0	-0.3	-0.3	-0.1
Neuroticism score	0.2	0.5	2.3	-0.5	-0.5	-0.8	-0.4	0.5	-0.5	-1.3	-0.6	-1.5	-0.7	-0.7	-0.5	-0.8	-0.5	-0.4	-0.2	-0.9	-0.1	-0.5	-0.5	-0.5	-0.4	-0.6	-0.9
Arm fat percentage (right)	0.2	0.9	6.1	-0.6	-0.6	-1.2	-0.7	-0.9	-0.6	1.1	-0.0	-1.5	1.4	-0.7	-0.6	-1.1	-0.6	-0.6	-0.3	-1.0	-2.5	-0.2	-0.4	-0.8	-0.4	-0.9	-0.2
Time employed in main current job	0.2	0.3	1.0	0.5	0.5	0.7	0.5	0.4	0.5	-0.3	0.4	0.8	-0.4	0.6	0.5	0.5	0.4	0.5	0.6	0.0	1.0	0.8	0.4	0.2	0.3	0.5	-0.0
Number of live births	0.2	0.3	1.5	0.6	0.6	0.2	0.2	0.2	0.6	0.3	0.5	0.4	0.2	0.5	0.6	0.5	0.8	0.6	0.5	1.2	0.8	0.2	0.3	0.9	0.6	0.4	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.5	0.5	0.4	0.4	0.6	0.1	0.4	0.2	0.7	-0.2	0.3	0.4	0.4	0.3	0.5	0.5	0.3	0.1	-0.7	0.7	0.6	1.2	0.5	0.4	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	1.6	-0.8	-0.8	-0.9	-0.9	-1.1	-0.8	-0.0	-0.4	-0.7	-0.0	-0.7	-0.8	-1.0	-0.7	-0.7	-0.5	0.0	-0.6	-1.0	-0.7	-0.7	-0.6	-0.8	-1.3
Pulse wave Arterial Stiffness index	0.2	0.2	1.0	-0.2	-0.1	0.0	-0.1	0.2	-0.1	0.9	0.5	0.9	1.0	-0.1	-0.2	-0.1	-0.1	-0.2	0.2	-0.0	1.0	-0.1	0.1	-0.3	0.0	0.1	-0.6
Impedance of arm (left)	0.2	0.9	8.4	0.7	0.8	1.1	0.8	1.5	0.7	-0.3	0.0	-0.1	-0.8	0.6	0.7	1.2	0.7	0.7	1.1	0.5	2.9	1.1	0.6	-0.3	0.6	0.8	-0.6
Birth weight of first child	0.2	0.4	1.4	-0.5	-0.5	-0.6	-0.2	-0.2	-0.5	-1.0	-0.2	0.2	-1.2	-0.6	-0.5	-0.6	-0.6	-0.6	-0.5	-0.8	1.2	-0.6	-0.4	-0.7	-0.6	-0.6	-0.0
Loud music exposure frequency	0.2	0.2	1.3	0.4	0.3	-0.6	0.3	-0.3	0.4	-0.4	0.4	0.4	0.1	0.2	0.3	-0.4	0.4	0.4	-0.2	1.2	-0.4	-0.3	0.3	0.0	0.3	0.1	-0.5
Gout (self-reported)	0.2	0.3	1.3	-0.4	-0.5	-0.7	-0.6	-0.7	-0.4	0.1	-0.3	-1.0	0.6	-0.4	-0.5	-0.6	-0.3	-0.4	-1.1	0.4	-1.0	-0.5	-0.6	-0.0	-0.3	-0.5	0.3
Arm fat-free mass (right)	0.2	1.1	2.8	-1.1	-1.2	-1.5	-0.9	-0.9	-1.1	0.1	-0.5	-0.3	0.2	-1.2	-1.1	-1.4	-1.1	-1.1	-0.7	-1.1	-1.7	-1.7	-0.8	-0.2	-0.9	-1.1	0.7
Number of children fathered	0.2	0.3	1.7	0.1	0.0	-1.1	-0.6	0.1	0.1	1.0	0.3	-0.6	1.3	-0.2	0.1	-0.6	0.1	0.1	0.5	0.1	0.4	-0.2	-0.4	-0.4	0.2	-0.2	-0.4
Heart disease (mother)	0.2	0.2	1.4	0.1	0.1	-0.3	0.1	-0.0	0.1	0.7	0.5	-0.8	0.8	0.0	0.1	-0.4	0.2	0.1	0.3	0.6	-0.5	-0.0	0.1	1.2	0.1	0.0	0.5
Arm predicted mass (right)	0.2	1.1	2.9	-1.2	-1.2	-1.4	-1.0	-0.8	-1.2	-0.2	-0.5	-0.2	-0.0	-1.2	-1.2	-1.3	-1.2	-1.2	-0.8	-1.1	-1.3	-1.7	-0.8	-0.3	-1.0	-1.1	0.5
Age at last live birth	0.2	0.3	2.0	0.2	0.2	0.0	-0.1	0.4	0.2	-1.0	-0.3	0.9	-0.9	0.2	0.2	-0.3	0.1	0.2	0.1	-0.6	1.2	-0.1	-0.3	-1.0	0.1	-0.0	-1.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	1.0	-0.4	-0.4	-1.0	-0.5	-0.7	-0.4	-0.0	-0.1	0.5	-0.1	-0.4	-0.3	-0.9	-0.3	-0.4	-0.4	-0.3	-0.2	-0.8	-0.6	-0.1	-0.5	-0.6	-0.4
Commuting to job workplace: Car/motor vehicle	0.2	0.3	2.4	-0.4	-0.4	-0.1	-0.2	-0.6	-0.4	1.5	0.3	0.6	1.3	-0.2	-0.3	-0.1	-0.4	-0.4	-0.3	-0.2	-0.1	-0.2	0.2	0.6	-0.3	-0.2	0.5
Long-standing illness, disability or infirmity	0.2	0.3	1.1	-0.4	-0.4	-1.1	-0.6	-0.8	-0.4	-0.3	0.0	0.2	0.1	-0.5	-0.4	-1.0	-0.4	-0.5	-0.2	-0.4	0.4	-0.6	-0.4	-0.0	-0.4	-0.6	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.5	-0.3	-0.2	0.3	0.3	-0.7	-0.3	-0.5	0.5	-0.8	-0.5	0.1	-0.3	0.2	-0.3	-0.3	-0.5	0.0	-0.5	0.1	0.1	-1.2	-0.3	0.0	-0.1
Qualifications: nursing, teaching	0.2	0.3	0.6	0.5	0.5	0.7	0.4	0.5	0.5	0.2	0.3	-0.1	-0.2	0.7	0.4	0.8	0.6	0.5	0.3	-0.1	0.8	0.8	0.5	0.7	0.4	0.7	0.0
Medication for cholesterol	0.2	0.2	1.1	0.5	0.5	0.4	0.3	0.8	0.5	-0.6	-0.1	-0.1	-0.4	0.3	0.5	0.4	0.5	0.5	-0.2	1.1	0.3	0.4	0.2	0.9	0.4	0.3	-0.0
Number of self-reported non-cancer illnesses	0.2	0.3	2.2	0.2	0.2	-0.2	0.4	-0.2	0.2	0.5	0.6	1.5	1.2	0.4	0.2	0.1	0.1	0.2	-0.0	0.5	0.6	-0.1	0.5	-1.0	0.3	0.3	0.3
Guilty feelings	0.2	0.4	1.3	-0.6	-0.6	-0.6	-0.6	-0.2	-0.6	-0.1	-0.5	-0.6	0.1	-0.7	-0.6	-0.6	-0.7	-0.6	0.0	-0.9	0.4	-0.7	-0.2	-1.1	-0.6	-0.6	-0.6
Wears glasses or contact lenses	0.2	0.2	0.7	-0.2	-0.2	-0.8	-0.5	-0.2	-0.1	-0.4	-0.8	-0.8	-0.6	-0.5	-0.1	-0.5	-0.2	-0.1	-0.1	-0.6	-0.1	-0.7	-0.5	0.1	-0.4	-0.6	-0.5
Hearing aid user	0.2	0.3	1.7	-0.4	-0.4	-0.3	-0.3	-0.6	-0.4	-0.7	0.0	-0.3	-0.8	-0.1	-0.4	-0.4	-0.4	-0.4	-0.9	-0.1	-1.3	0.1	-0.6	-0.0	-0.5	-0.2	-0.2
Number of operations (self-reported)	0.2	0.3	0.9	0.6	0.5	-0.3	0.3	0.5	0.6	0.3	0.6	0.7	0.5	0.4	0.5	0.2	0.6	0.6	0.4	0.6	0.3	-0.1	0.4	0.9	0.8	0.5	0.8
Average weekly beer plus cider intake	0.2	0.2	0.7	0.4	0.4	0.4	0.7	0.2	0.4	0.7	0.8	0.3	0.7	0.5	0.3	0.4	0.4	0.4	0.1	0.2	-0.0	0.6	0.6	0.4	0.4	0.6	0.8
Commuting to job workplace: Cycle	0.2	0.2	0.6	0.5	0.5	0.0	0.4	0.6	0.5	-0.4	0.2	0.4	-0.2	0.3	0.5	0.2	0.4	0.5	0.6	0.7	0.6	0.6	0.4	0.5	0.7	0.5	0.7
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	2.4	-0.0	-0.1	-0.7	-0.5	-1.5	-0.0	-0.1	0.2	-0.4	0.4	0.1	0.0	-0.6	-0.1	-0.0	-0.3	-0.0	-0.7	-0.7	-0.3	-0.2	-0.0	-0.3	0.1
Arm predicted mass (left)	0.2	0.9	2.8	-1.0	-1.0	-1.4	-0.8	-0.9	-1.0	0.4	-0.2	0.2	0.6	-1.0	-1.0	-1.4	-1.0	-1.0	-0.6	-1.1	-1.7	-1.4	-0.6	-0.3	-0.8	-1.0	0.4
Bipolar Disorder (2018)	0.1	0.1	0.7	-0.0	-0.1	-0.5	0.0	-0.8	-0.0	-0.3	-0.3	0.7	-0.6	-0.1	-0.1	-0.5	-0.0	-0.1	-0.2	-0.5	-0.4	-0.0	-0.0	-0.2	-0.1	-0.5	-0.3
Reaction Time	0.1	0.2	1.0	0.4	0.3	-0.6	0.3	0.4	0.4	-0.4	0.3	-0.1	-0.5	0.3	0.4	-0.6	0.4	0.3	0.6	-0.2	-0.3	0.5	-0.1	-0.3	0.4	0.2	-1.0
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.2	-0.4	-0.4	-0.7	-0.5	0.4	-0.4	-1.0	-0.7	-0.5	-0.8	-0.7	-0.4	-0.6	-0.4	-0.4	-0.2	-0.0	-1.1	-0.4	-0.5	-0.0	-0.4	-0.6	-0.0
Ovarian Cancer	0.1	0.1	0.4	-0.5	-0.5	-0.1	-0.1	-0.2	-0.5	0.4	0.2	-0.0	0.6	-0.4	-0.5	-0.4	-0.4	-0.5	0.3	-0.4	0.1	-0.4	0.2	0.1	-0.4	-0.2	-0.3
Prostate Cancer	0.1	0.2	1.0	-0.3	-0.3	-0.3	-0.3	-0.5	-0.3	0.2	0.1	-0.4	0.5	-0.4	-0.4	-0.1	-0.4	-0.3	-0.8	0.3	-0.4	-0.6	-0.2	-1.0	-0.2	-0.5	0.6
Age at First Birth	0.1	0.1	0.2	0.4	0.3	-0.2	0.0	0.5	0.4	0.1	0.2	0.4	0.2	0.2	0.4	0.1	0.3	0.4	0.4	-0.3	-0.2	0.5	0.0	-0.3	0.3	0.3	-0.0
Body Mass Index (BMI) (2010)	0.1	0.2	0.9	0.5	0.5	-0.0	0.3	0.3	0.5	-0.8	-0.3	0.4	-0.7	0.3	0.5	0.2	0.3	0.5	0.3	-0.2	0.1	0.5	0.1	1.0	0.5	0.3	-0.2
Lupus	0.1	0.1	0.9	0.1	0.1	0.2	-0.1	0.6	0.1	-0.9	-0.6	0.2	-0.6	-0.0	0.0	0.2	0.0	0.1	-0.2	0.2	0.7	-0.0	-0.0	-0.1	-0.1	0.0	-0.1
Schizophrenia (2014)	0.1	0.2	1.1	0.1	0.1	-0.6	-0.3	-0.7	0.1	1.0	0.6	0.4	1.0	0.1	0.0	-0.6	0.3	0.1	0.2	-0.3	-0.2	-0.2	-0.1	0.2	0.2	-0.0	0.4
Blood White Count	0.1	0.5	4.5	-0.1	-0.1	0.4	0.2	0.4	-0.1	0.8	0.3	1.7	0.9	-0.2	-0.2	0.4	-0.2	-0.2	0.1	-1.0	2.1	0.8	0.5	-0.6	0.2	0.1	0.7
Height	0.1	1.5	2.6	-1.5	-1.5	-1.4	-1.3	-0.9	-1.5	-0.5	-1.1	0.2	-0.9	-1.4	-1.6	-1.6	-1.5	-1.5	-0.7	-1.3	-0.0	-1.6	-1.2	-1.3	-1.4	-1.3	-0.2
Waist Hip Ratio (WHR)	0.1	0.4	4.2	-0.1	-0.1	-0.4	-0.3	-0.1	-0.1	0.2	0.7	-0.1	0.9	-0.2	-0.1	-0.3	-0.2	-0.1	0.4	-0.5	0.6	0.2	-0.1	-2.0	-0.1	-0.2	-1.9
Hair Pigment	0.1	2.6	9.5	1.6	1.6	2.0	1.4	1.5	1.6	0.8	1.1	2.3	0.8	1.6	1.6	1.7	1.6	1.6	1.2	2.0	3.1	-0.1	1.4	1.5	1.5	1.3	1.4
Diabetes (mother)	0.1	0.2	0.6	0.1	0.1	0.4	0.5	0.5	0.1	0.8	0.3	0.4	0.8	0.3	0.1	0.2	-0.1	0.1	0.5	0.4	-0.1	0.5	0.6	-0.4	0.3	0.4	0.7
Pack years adult smoking proportion	0.1	0.2	2.0	-0.2	-0.2	-0.3	-0.3	-1.1	-0.1	0.1	-0.0	-0.9	0.6	0.1	-0.1	-0.1	-0.1	-0.1	-0.3	-0.1	-1.4	-0.1	-0.1	-0.4	0.1	-0.0	0.4
Impedance of leg (right)	0.1	0.3	1.7	0.0	0.1	0.8	0.3	0.4	0.0	0.4	-0.0	-0.8	0.4	0.2	-0.0	0.7	0.0	0.0	0.4	-0.0	1.3	0.4	0.4	-1.1	-0.0	0.4	-1.1
Relative age voice broke	0.1	0.2	2.6	0.1	0.1	0.2	0.1	-0.1	0.1	-1.0	-0.5	-0.3	-1.6	0.2	0.1	0.2	0.2	0.1	-0.3	0.0	0.3	-0.2	-0.2	-0.1	-0.1	0.1	-0.5
Taking other prescription medications	0.1	0.2	2.1	-0.0	-0.0	-0.3	0.3	-0.4	-0.0	0.6	0.5	1.0	1.5	0.2	0.0	-0.2	-0.0	-0.0	0.1	-0.3	0.6	-0.1	0.5	-0.1	0.1	0.2	0.1
Age when periods started (menarche)	0.1	0.2	2.6	-0.4	-0.4	0.4	0.3	-0.0	-0.4	-0.3	-0.0	0.4	-0.1	-0.2	-0.5	0.1	-0.5	-0.4	-0.3	-0.3	1.6	-0.2	0.2	-0.4	-0.4	0.1	0.1
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.9	-0.4	-0.4	-0.3	-0.3	-0.1	-0.4	-0.4	-0.6	0.1	-0.9	-0.4	-0.4	-0.3	-0.5	-0.4	-0.4	-0.2	-0.5	-0.1	-0.2	-0.5	-0.4	-0.4	0.5
Sitting height	0.1	0.4	1.2	-0.8	-0.8	-0.8	-0.6	-0.2	-0.8	0.1	-0.1	-0.0	0.1	-0.7	-0.8	-0.6	-0.8	-0.8	0.1	-0.9	0.6	-1.1	-0.5	-0.9	-0.6	-0.6	-0.5
Impedance of leg (left)	0.1	0.4	2.3	0.2	0.3	0.9	0.4	0.7	0.2	0.4	0.1	-0.8	0.7	0.4	0.2	1.0	0.2	0.2	0.7	0.4	1.5	0.7	0.6	-1.0	0.3	0.5	-0.9
Number of incorrect matches in round	0.1	0.2	1.1	-0.1	-0.0	0.2	-0.2	0.3	-0.0	0.4	0.1	1.1	0.3	-0.0	-0.0	0.2	-0.1	-0.1	0.2	-0.5	0.9	-0.3	-0.2	-0.8	0.1	-0.0	0.5
Past tobacco smoking	0.1	0.1	1.4	0.1	0.1	-0.0	0.1	0.1	0.1	-0.5	-0.0	0.1	-0.3	0.0	0.1	-0.2	-0.1	0.1	0.4	-0.3	-0.1	0.3	0.2	-1.2	0.0	0.1	0.1
Financial difficulties in last 2 years	0.1	0.1	0.8	-0.2	-0.2	0.4	0.2	0.0	-0.2	0.5	0.3	0.8	0.9	0.1	-0.3	0.3	-0.2	-0.2	-0.2	0.0	0.8	0.1	0.3	-0.1	0.1	0.1	0.1
Medication: Lansoprazole	0.1	0.1	1.2	-0.1	-0.1	0.3	-0.1	-0.4	-0.1	0.6	-0.1	-0.3	1.1	0.1	-0.1	-0.0	-0.2	-0.1	-0.2	0.1	-1.1	0.6	0.1	0.1	0.1	0.1	0.0
Lung cancer (father)	0.1	0.2	1.2	-0.2	-0.2	0.3	0.2	-0.2	-0.2	0.1	0.1	0.4	0.2	0.1	-0.2	-0.2	-0.2	-0.2	-0.2	-0.2	1.1	0.5	0.3	0.6	-0.1	0.1	1.1
Hair/balding pattern: Pattern 4	0.1	0.2	0.7	0.4	0.4	0.4	0.3	-0.1	0.4	0.4	0.8	0.3	0.5	0.5	0.4	0.2	0.4	0.5	0.3	0.9	0.2	0.0	0.3	0.7	0.5	0.3	0.1
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.8	0.0	0.0	0.6	0.4	-0.4	-0.0	-0.1	0.2	0.9	-0.3	0.4	-0.0	0.5	-0.1	-0.0	-0.4	-0.1	0.0	0.5	0.2	-0.3	-0.1	0.3	-0.1
Blood clot in the leg (DVT)	0.1	0.1	0.7	0.1	0.1	-0.7	-0.3	-0.1	0.1	-0.2	-0.4	0.1	-0.3	-0.0	0.1	-0.7	0.0	0.1	-0.1	-0.0	-0.3	-0.4	-0.3	0.8	0.2	-0.1	-0.1
Medication: Amlodipine	0.1	0.2	1.2	0.3	0.3	0.1	0.0	0.9	0.3	-1.1	-0.4	0.5	-0.6	0.2	0.3	0.2	0.2	0.3	0.2	0.6	-0.7	0.1	-0.1	-0.4	0.3	0.4	0.4
Birth weight	0.1	0.2	1.8	0.1	0.1	0.1	-0.4	0.1	0.1	-0.7	0.1	-1.4	-0.5	0.2	0.1	0.2	0.1	0.1	0.7	-0.4	-1.1	0.1	-0.4	0.1	0.2	0.0	0.4
Forced vital capacity (FVC), Best measure	0.1	0.2	0.7	0.4	0.4	0.5	0.4	0.5	0.4	-0.3	0.2	0.5	-0.7	0.5	0.3	0.5	0.4	0.4	0.5	0.7	0.8	0.1	0.2	0.6	0.4	0.5	-0.2
Worry too long after embarrassment	0.1	0.1	0.6	0.1	0.1	0.0	-0.2	0.4	0.1	-0.6	-0.3	-0.8	-0.6	-0.3	0.0	0.2	0.1	0.1	0.2	-0.7	0.6	-0.3	-0.1	0.0	0.1	-0.2	-0.0
Wheeze or whistling in the chest in last year	0.1	0.2	3.0	0.1	0.1	0.0	0.0	-0.3	0.1	0.0	-0.1	1.7	-0.0	0.1	0.1	0.2	0.1	0.1	-0.3	-0.2	0.9	-0.2	0.0	-0.6	0.1	-0.0	-0.5
Pulse wave peak to peak time	0.1	0.2	0.7	0.3	0.3	0.1	0.3	0.0	0.3	-0.7	-0.3	-0.6	-0.9	0.3	0.3	0.3	0.2	0.3	0.0	0.1	-0.7	0.3	0.1	0.3	0.1	0.1	0.8
Medication: Blood pressure	0.1	0.2	1.6	-0.1	-0.1	-0.4	-0.2	0.1	-0.1	0.7	0.2	-0.1	1.0	-0.2	-0.1	-0.3	-0.2	-0.1	-0.1	-0.3	-1.3	0.2	0.0	-0.5	-0.1	-0.1	0.3
Medication: Omeprazole	0.1	0.1	0.9	0.3	0.3	-0.2	-0.0	-1.0	0.3	0.2	0.6	0.3	0.4	0.4	0.4	-0.2	0.3	0.3	0.2	0.0	0.1	-0.4	0.1	0.0	0.3	0.1	0.3
Mean time to correctly identify matches	0.1	0.2	1.7	-0.1	-0.1	-0.8	-0.1	0.1	-0.1	-0.6	-0.1	-0.2	-0.7	-0.2	-0.1	-0.9	-0.1	-0.1	0.2	-0.8	-1.3	0.0	-0.5	-0.4	-0.2	-0.3	-0.9
Alcohol intake frequency.	0.1	0.2	0.7	-0.4	-0.4	-0.1	-0.2	-0.1	-0.4	-0.3	-0.1	-0.7	0.3	-0.3	-0.4	-0.1	-0.3	-0.4	-0.3	-0.8	-0.7	-0.4	-0.1	-0.7	-0.4	-0.2	-0.7
Had major operations	0.1	0.1	0.6	-0.1	-0.1	-0.0	-0.1	-0.2	-0.1	-0.8	-0.3	0.4	-0.8	-0.0	-0.1	-0.2	-0.0	-0.1	-0.2	-0.4	0.4	0.2	-0.1	0.0	-0.0	-0.0	-0.2
Leg pain on walking	0.1	0.2	1.6	0.1	0.0	-0.1	0.1	-0.6	0.1	0.7	0.8	-0.7	1.3	0.2	0.1	0.1	-0.0	0.0	-0.2	0.1	-0.4	0.3	0.1	0.0	0.2	0.1	0.6
Supplements: Vitamin C	0.1	0.2	1.0	0.1	0.1	-0.0	-0.1	0.3	0.1	-0.8	-0.5	-0.4	-0.8	0.0	0.1	0.3	0.1	0.1	-0.3	1.0	0.4	-0.2	-0.3	0.4	0.2	0.2	0.3
Smoking status: Previous	0.1	0.2	2.3	0.4	0.4	0.2	0.3	0.5	0.4	0.2	-0.1	0.2	-0.1	0.2	0.4	0.5	0.5	0.4	0.1	0.3	0.4	-0.0	0.1	1.5	0.4	0.1	0.2
Whole body fat-free mass	0.1	0.4	0.9	-0.7	-0.8	-0.9	-0.5	-0.4	-0.8	0.2	-0.1	0.0	0.2	-0.7	-0.8	-0.9	-0.7	-0.8	-0.4	-0.9	-1.0	-0.9	-0.3	-0.1	-0.5	-0.6	0.9
Leg fat-free mass (right)	0.1	0.5	1.3	-0.8	-0.8	-1.1	-0.6	-0.6	-0.8	0.2	-0.3	-0.2	-0.0	-0.8	-0.8	-1.1	-0.8	-0.8	-0.4	-0.9	-1.0	-0.9	-0.5	-0.2	-0.6	-0.8	0.6
Average weekly red wine intake	0.1	0.2	1.2	-0.2	-0.2	-0.7	-0.7	0.0	-0.2	-0.8	-0.6	-0.2	-1.1	-0.4	-0.2	-0.2	-0.1	-0.2	0.1	0.1	0.2	-0.2	-0.7	0.7	-0.3	-0.4	-0.3
Back pain experienced in last month	0.1	0.2	2.6	-0.2	-0.1	0.3	0.0	-0.3	-0.2	0.6	0.4	1.6	0.7	-0.0	-0.2	-0.0	-0.2	-0.2	-0.2	-0.2	-0.6	-0.3	0.1	-0.1	-0.1	-0.1	0.0
Osteoporosis (self-reported)	0.1	0.1	2.3	0.0	0.0	0.2	0.1	-0.2	0.0	-0.3	0.3	0.4	-0.0	0.0	0.1	-0.1	0.0	0.0	0.0	0.3	-1.5	-0.3	0.2	0.4	-0.2	0.1	0.2
Osteoarthritis (self-reported)	0.1	0.1	0.6	-0.4	-0.4	0.1	-0.1	-0.4	-0.4	-0.3	0.1	0.3	-0.3	-0.2	-0.4	-0.0	-0.5	-0.4	-0.8	-0.5	0.2	-0.1	-0.2	0.3	-0.4	-0.2	0.3
Medication: Gliclazide	0.1	0.1	0.5	-0.3	-0.3	-0.3	-0.4	-0.4	-0.3	0.3	0.3	-0.0	0.7	-0.2	-0.3	-0.4	-0.4	-0.3	0.0	-0.6	-0.5	0.2	-0.2	-0.3	-0.3	-0.3	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	1.7	-0.2	-0.2	-0.7	-0.3	-0.5	-0.2	0.3	-0.1	-0.6	0.2	-0.3	-0.2	-0.9	-0.1	-0.1	-0.0	-0.1	-1.3	-0.5	-0.2	0.1	-0.1	-0.3	-0.3
Whole body water mass	0.1	0.4	0.9	-0.6	-0.7	-0.8	-0.4	-0.4	-0.7	0.3	-0.0	0.1	0.3	-0.6	-0.7	-0.9	-0.6	-0.7	-0.3	-0.8	-0.9	-0.9	-0.3	-0.0	-0.4	-0.5	0.9
Leg predicted mass (right)	0.1	0.6	1.4	-0.9	-0.9	-1.1	-0.6	-0.6	-0.9	0.2	-0.3	-0.2	-0.0	-0.8	-0.9	-1.2	-0.9	-0.9	-0.5	-1.0	-0.9	-0.9	-0.5	-0.3	-0.6	-0.8	0.7
Average weekly champagne plus white wine intake	0.1	0.1	0.8	-0.1	-0.1	-0.1	-0.2	0.4	-0.1	-0.2	-0.8	0.5	-0.4	-0.2	-0.0	-0.2	-0.1	-0.1	-0.0	0.0	0.4	-0.4	-0.2	0.9	-0.0	-0.1	0.3
Miserableness	0.1	0.2	1.0	0.0	-0.0	-0.7	-0.2	-0.0	0.0	-0.6	-0.2	-1.0	-0.2	-0.1	-0.0	-0.4	0.0	0.0	-0.0	0.1	-0.9	0.0	-0.2	0.1	0.1	-0.2	-0.9
Mother’s age at death	0.1	0.2	1.1	0.1	0.1	0.3	-0.1	0.5	0.1	-0.9	-0.3	0.9	-0.5	-0.0	0.1	0.5	0.0	0.1	-0.3	0.2	1.1	-0.3	-0.2	0.6	0.1	-0.1	0.1
Ever smoked	0.1	0.1	0.5	-0.4	-0.4	-0.1	-0.3	-0.3	-0.4	0.1	-0.3	-0.3	0.1	-0.3	-0.4	-0.1	-0.2	-0.4	-0.6	0.4	0.1	-0.6	-0.5	0.7	-0.3	-0.3	-0.5
Basal metabolic rate	0.1	0.7	2.2	-0.9	-1.0	-1.2	-0.7	-0.7	-0.9	0.4	-0.2	-0.4	0.5	-0.9	-0.9	-1.2	-0.9	-0.9	-0.5	-1.1	-1.5	-1.1	-0.5	-0.4	-0.7	-0.9	0.6
Arm fat-free mass (left)	0.1	0.6	2.9	-0.7	-0.7	-1.1	-0.5	-0.7	-0.7	0.7	0.1	0.2	0.8	-0.7	-0.7	-1.1	-0.7	-0.7	-0.3	-0.8	-1.7	-1.0	-0.3	-0.0	-0.5	-0.7	0.8
Irritability	0.1	0.2	0.8	0.4	0.4	0.1	0.4	0.9	0.4	-0.1	0.3	0.6	0.3	0.3	0.4	0.2	0.3	0.4	0.8	-0.0	-0.1	0.6	0.4	-0.2	0.4	0.3	0.2
Age started oral contraceptive pill	0.1	0.1	1.2	0.2	0.2	-0.0	0.0	0.4	0.2	-0.1	0.1	0.9	-0.3	0.0	0.2	-0.1	0.1	0.1	0.6	-0.6	1.1	0.1	0.1	-0.1	-0.0	0.2	-0.2
Ever depressed for a whole week	0.1	0.2	0.7	-0.5	-0.5	-0.2	-0.5	-0.2	-0.5	0.3	-0.1	-0.8	0.5	-0.6	-0.5	-0.3	-0.5	-0.5	-0.4	0.0	0.1	-0.4	-0.4	-0.1	-0.3	-0.5	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.8	0.1	0.1	-0.6	-0.3	-0.1	0.1	-0.2	-0.5	-0.1	-0.3	-0.1	0.1	-0.6	0.1	0.1	-0.1	0.1	-0.3	-0.3	-0.3	0.9	0.3	-0.2	0.0
Pack years of smoking	0.1	0.2	1.6	-0.2	-0.2	-0.4	-0.4	-1.0	-0.2	-0.0	-0.1	-0.7	0.5	0.0	-0.1	-0.2	-0.1	-0.1	-0.3	-0.2	-1.3	-0.1	-0.2	-0.4	0.0	-0.1	0.3
Impedance of whole body	0.1	0.6	5.1	0.4	0.5	1.1	0.6	1.2	0.4	0.0	0.0	-0.4	-0.2	0.5	0.4	1.1	0.4	0.4	0.9	0.3	2.3	1.0	0.5	-0.7	0.4	0.7	-1.0
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.5	0.3	0.3	0.2	0.5	0.7	0.3	-0.4	0.2	-0.3	0.2	0.1	0.3	0.4	0.3	0.3	0.3	0.4	-0.2	0.6	0.7	0.4	0.2	0.3	0.2
Triglycerides	0.0	0.1	0.5	-0.1	-0.1	-0.4	-0.1	-0.4	-0.1	-0.0	-0.3	-0.7	-0.1	-0.0	-0.1	-0.1	0.0	-0.1	-0.3	-0.2	-0.7	-0.1	-0.1	-0.2	-0.2	-0.1	-0.4
Tanning	0.0	0.4	1.7	-0.4	-0.4	0.4	0.1	-0.3	-0.5	1.3	0.4	-0.6	1.3	-0.2	-0.5	-0.1	-0.5	-0.5	0.1	-0.7	-0.9	1.1	0.5	0.2	-0.3	-0.2	1.1
Fluid intelligence score	0.0	0.1	0.4	0.2	0.3	0.3	0.2	0.6	0.2	-0.5	0.1	0.2	-0.4	0.1	0.2	0.4	0.2	0.2	0.4	0.3	-0.1	0.4	0.1	-0.3	0.2	0.2	0.1
Trunk fat-free mass	0.0	0.2	1.3	-0.5	-0.5	-0.5	-0.2	-0.1	-0.5	0.3	0.1	0.3	0.2	-0.4	-0.5	-0.5	-0.5	-0.5	-0.1	-0.5	-0.7	-0.8	-0.1	0.1	-0.3	-0.3	1.1
Forced expiratory volume in 1-second (FEV1)	0.0	0.1	0.9	-0.3	-0.3	-0.2	-0.2	-0.5	-0.3	0.5	0.1	-0.1	0.2	-0.1	-0.3	-0.4	-0.2	-0.3	0.1	0.2	-0.3	-0.2	-0.1	-0.3	-0.1	-0.1	-0.9
Trunk predicted mass	0.0	0.2	1.5	-0.4	-0.4	-0.4	-0.1	0.0	-0.4	0.3	0.2	0.5	0.3	-0.3	-0.4	-0.5	-0.4	-0.4	0.0	-0.5	-0.6	-0.7	0.0	0.2	-0.2	-0.2	1.2
Standing height	0.0	0.3	3.2	-0.1	-0.1	0.4	0.4	1.1	-0.1	-0.0	0.0	0.8	-0.6	0.0	-0.2	0.4	-0.1	-0.1	0.9	-0.3	1.8	-0.2	0.3	-0.1	0.1	0.4	0.5
Peak expiratory flow (PEF)	0.0	0.1	0.8	-0.2	-0.2	0.1	-0.0	-0.4	-0.3	0.1	-0.1	0.4	0.1	-0.0	-0.3	-0.2	-0.3	-0.3	0.1	-0.1	-0.2	-0.1	0.1	-0.6	-0.1	-0.1	-0.9

Hub : Genes

PLGRKT

Models

Trait associations