Best TWAS P=2.05e-08 · Best GWAS P=3.73e-07 conditioned to 0.0994
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | PPP2R3C | 0.22 | 0.11 | enet | 15 | 0.24 | 3.2e-09 | -4.6 | -5.2 | 2.5e-07 | 0.87 | 0.02 | 0.96 | FALSE |
| 2 | GTEx | Muscle Skeletal | FAM177A1 | 0.16 | 0.09 | enet | 35 | 0.15 | 6.0e-15 | -4.1 | -5.3 | 1.1e-07 | 0.66 | 0.11 | 0.79 | FALSE |
| 3 | METSIM | Adipose | KIAA0391 | 0.05 | 0.03 | lasso | 3 | 0.02 | 5.1e-04 | -5.1 | -5.1 | 2.8e-07 | 0.97 | 0.00 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | KIAA0391 | 0.07 | 0.01 | enet | 6 | 0.05 | 6.5e-06 | 3.2 | -5.6 | 2.1e-08 | 0.69 | 0.01 | 0.90 | TRUE |