Best TWAS P=3.84e-10 · Best GWAS P=3.25e-11 conditioned to 9.56e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | CTD-3203P2.1 | 0.21 | 0.05 | lasso | 6 | 0.09 | 8.5e-07 | -5.7 | 6.3 | 3.8e-10 | 0.03 | 0.62 | 0.23 | TRUE |
| 2 | YFS | Blood | IL4R | 0.13 | 0.04 | enet | 35 | 0.10 | 2.0e-32 | -4.6 | 5.8 | 5.6e-09 | 0.02 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | JMJD5 | 0.04 | 0.04 | blup | 67 | 0.02 | 3.5e-03 | -5.7 | 6.0 | 1.6e-09 | 0.18 | 0.20 | 0.50 | FALSE |