TWAS hub - IL4R

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0295	0.0109	0.0018	0.013	0.006	0.008	0.008	0.007	2.4e-05	2.9e-03	8.1e-04	1.0e-03	2.0e-03
2	YFS	Blood	0.1282	0.0217	0.0000	0.042	0.088	0.105	0.096	0.098	1.2e-13	2.6e-27	2.0e-32	8.9e-30	2.2e-30

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Respiratory disease	29.7	66.0	74.5	-7.6	-8.6
Asthma	23.8	46.9	53.7	-6.3	-7.3
Asthma (self-reported)	23.3	46.5	53.0	-6.3	-7.3
Blood Eosinophil Count	17.6	135.8	144.0	-11.3	-12.0
Medication: Ventolin 100micrograms inhaler	12.3	15.8	18.2	-4.3	-3.7
Allergy	11.3	25.9	34.0	4.2	5.8
Allergy or Eczema	7.9	20.9	27.1	-3.8	-5.2
Ever had hysterectomy (womb removed)	7.4	8.4	8.8	2.8	3.0
Medication: Seretide 50 evohaler	7.4	8.5	10.6	-3.2	-2.5
Hayfever, allergic rhinitis or eczema	7.0	15.3	22.3	-2.9	-4.7
Wheeze or whistling in the chest in last year	5.9	10.5	10.9	-3.3	-3.2
Age at last live birth	4.6	6.7	11.3	-3.4	-1.4
Hayfever/allergic rhinitis (self-reported)	4.4	5.9	9.2	-1.6	-3.0
Age at first live birth	4.2	7.5	9.1	-3.0	-2.4
Mouth/teeth dental problems: Loose teeth	4.2	5.0	5.3	2.3	2.1
Migraine (self-reported)	4.2	5.2	6.2	2.0	2.5
Bipolar Disorder (2011)	4.1	4.0	4.2	-1.9	-2.1
Chronic bronchitis/emphysema (mother)	3.5	4.1	6.3	-2.5	-1.4
Alzheimer’s Disease (in mother)	3.3	3.9	5.5	-1.5	-2.4
Supplements: Zinc	3.1	3.4	6.5	2.6	0.6
Had other major operations	3.1	3.8	6.1	-1.2	-2.5
Alcohol drinker status: Never	3.1	3.7	5.7	1.4	2.4
Taking other prescription medications	3.0	4.6	6.5	-2.6	-1.6
Pain all over the body in last month	2.7	2.9	5.4	2.3	0.6
Multivitamins +/- minerals	2.6	3.3	4.1	2.0	1.6
Serious illness, injury or assault of a close relative in last 2 years	2.6	3.0	4.2	-1.3	-2.1
Number of full brothers	2.6	3.3	3.9	1.6	2.0
Number of live births	2.4	3.3	5.7	1.0	2.4
Qualifications: College or University degree	2.4	7.6	7.7	-2.8	-2.7
Alcohol intake frequency.	2.3	5.3	8.4	1.5	2.9
Hair/balding pattern: Pattern 3	2.2	3.3	6.1	-2.5	-0.7
Ever had prostate specific antigen (PSA) test	2.2	2.5	3.9	-1.1	-2.0
Comparative body size at age 10	2.1	5.7	6.6	2.6	2.2
Reason for reducing amount of alcohol drunk: Health precaution	2.1	2.4	4.5	0.5	2.1
Qualifications: A levels/AS levels or equivalent	2.0	4.5	6.4	-1.6	-2.5
Number of children fathered	2.0	2.3	3.5	1.9	1.0
Bilateral oophorectomy (both ovaries removed)	1.9	2.2	2.8	1.7	1.2
Serious illness, injury or assault to yourself	1.9	2.3	2.9	1.3	1.7
Fractured/broken bones in last 5 years	1.8	2.4	3.8	1.0	1.9
Hair/balding pattern: Pattern 2	1.7	2.2	2.7	1.7	1.3
Noisy workplace	1.7	2.1	3.9	0.5	2.0
Coronary Artery Disease (CAD)	1.6	1.9	2.4	-1.6	-1.2
Mean Putamen Volume	1.6	1.8	3.3	1.8	0.6
Medication: Lansoprazole	1.6	1.8	3.1	0.8	1.8
Gout (self-reported)	1.6	2.2	2.3	1.5	1.4
Financial situation satisfaction	1.6	2.0	3.5	-0.7	1.9
HDL Cholesterol	1.5	2.5	5.1	-0.1	2.2
Pain experienced in last month	1.5	2.5	4.0	-1.0	-2.0
Alcohol drinker status: Previous	1.5	1.7	2.2	1.1	1.5
Blood White Count	1.4	10.3	14.5	-3.8	-2.5
Ever used hormone-replacement therapy (HRT)	1.4	1.8	2.4	1.0	1.6
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	4.7	1.3	2.2
Long-standing illness, disability or infirmity	1.4	2.1	2.4	-1.6	-1.3
Eye problems/disorders: Cataract	1.4	1.6	2.0	-1.1	-1.4
Osteoarthritis (self-reported)	1.4	1.8	1.8	1.3	1.4
Number of self-reported non-cancer illnesses	1.4	2.5	2.6	-1.5	-1.6
Medication: Lisinopril	1.4	1.9	1.9	1.4	1.4
Commuting to job workplace: Cycle	1.4	1.8	3.5	-1.9	-0.1
Heart attack/myocardial infarction (self-reported)	1.4	1.8	2.9	-1.7	-0.8
Primary Biliary Cirrhosis	1.3	1.8	2.7	1.0	-1.6
Frequency of depressed mood in last 2 weeks	1.3	1.8	2.5	1.0	1.6
Myopia	1.3	1.8	2.8	-0.9	-1.7
Severe depression (siblings)	1.2	1.4	2.5	-0.5	1.6
Heart attack	1.2	1.6	2.6	-1.6	-0.7
Alcohol intake versus 10 years previously	1.2	1.8	2.3	-1.1	1.5
Length of working week for main job	1.2	1.3	2.4	1.6	0.5
Birth weight of first child	1.2	2.1	3.0	1.1	1.7
Emphysema/chronic bronchitis	1.2	1.3	2.3	-0.6	-1.5
Illnesses of siblings: Diabetes	1.2	1.5	3.0	-1.7	-0.2
Guilty feelings	1.2	1.8	3.1	0.7	1.8
Illnesses of father: High blood pressure	1.2	1.5	3.0	1.7	-0.0
Diabetes (mother)	1.1	1.4	2.8	0.1	1.7
Townsend deprivation index at recruitment	1.1	1.6	3.0	0.4	1.7
High blood pressure (mother)	1.1	1.6	1.8	1.2	1.4
Supplements: Vitamin C	1.1	1.4	2.3	-0.7	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	2.2	-1.5	-0.4
Average weekly champagne plus white wine intake	1.1	1.6	3.1	1.8	0.0
Medication: Atorvastatin	1.1	1.4	2.2	-0.8	-1.5
Neuroticism (Nagel 2018)	1.0	2.2	4.2	0.5	2.0
Schizophrenia (2018)	1.0	2.1	4.1	-2.0	-0.2
Lung FEV1/FVC ratio	1.0	4.9	7.9	1.4	2.8
High blood pressure	1.0	2.7	4.3	1.1	2.1
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	1.4	-1.2	-1.0
Time employed in main current job	1.0	1.2	2.2	1.5	-0.3
Major Depression (MDD)	0.9	1.1	1.8	-1.4	-0.7
Ovarian Cancer	0.9	1.1	2.1	1.4	0.4
Prostate Cancer	0.9	1.2	2.3	-1.5	-0.4
LDL Cholesterol	0.9	1.5	1.9	1.4	1.1
Schizophrenia (2014)	0.9	1.9	3.8	-1.9	-0.1
Age when periods started (menarche)	0.9	2.2	3.6	-1.9	-0.9
Qualifications: None of the above	0.9	1.9	3.6	-0.4	1.9
Medication: Ramipril	0.9	1.1	1.5	0.9	1.2
Fluid intelligence score	0.9	1.9	3.2	-0.8	-1.8
Hair/balding pattern: Pattern 4	0.9	2.3	4.2	0.6	2.1
Shortness of breath walking on level ground	0.9	1.1	1.3	1.1	1.0
Had major operations	0.9	1.1	1.1	1.0	1.1
Bipolar Disorder or Schizophrenia	0.8	1.8	3.4	-1.8	-0.5
Triglycerides	0.8	1.3	2.3	-0.6	-1.5
Smoking Status	0.8	1.9	3.7	0.4	1.9
Medication: Co-codamol	0.8	0.9	1.6	-1.3	0.4
Qualifications: CSEs or equivalent	0.8	1.1	1.5	-0.8	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.9	2.3	1.2	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	2.4	-1.5	0.4
Loud music exposure frequency	0.8	0.9	1.7	0.4	1.3
Leg pain on walking	0.8	1.0	1.9	-0.2	1.4
Knee pain experienced in last month	0.8	1.3	2.5	-0.1	1.6
Commuting to job workplace: Walk	0.8	0.8	1.4	-1.2	-0.5
Mineral and other dietary supplements	0.8	1.1	1.3	-1.1	-1.0
Supplements: Fish oil (including cod liver oil)	0.8	1.0	1.2	1.1	0.9
Medication: Bendroflumethiazide	0.8	1.2	1.3	-1.2	-1.1
Alzheimer’s Disease (including proxy)	0.7	1.0	1.8	-0.5	-1.4
Ulcerative Colitis	0.7	0.9	1.4	0.7	1.2
Chronotype (morning person)	0.7	1.7	2.6	1.6	-0.9
Supplements: Glucosamine	0.7	0.8	1.4	1.2	0.6
Chronic bronchitis/emphysema (father)	0.7	0.8	1.6	-0.3	-1.3
Forced expiratory volume in 1-second (FEV1)	0.7	2.2	3.1	1.7	1.2
Happiness	0.7	0.8	0.8	-0.9	-0.9
Mouth/teeth dental problems: Dentures	0.7	1.2	2.3	-0.3	1.5
Pulse wave reflection index	0.7	0.8	1.3	1.1	0.6
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	1.6	1.3	-0.3
Family relationship satisfaction	0.7	0.9	1.1	0.8	1.0
Irritability	0.7	1.1	2.2	-1.5	-0.2
Heart disease (siblings)	0.7	0.9	1.8	-0.0	1.4
Depressed Affect (Nagel 2018)	0.6	1.3	2.2	0.6	1.5
Pack years adult smoking proportion	0.6	0.9	1.1	0.8	1.1
Maternal smoking around birth	0.6	0.8	1.1	-0.8	-1.0
Forced vital capacity (FVC)	0.6	2.2	3.6	1.9	0.9
Mouth/teeth dental problems	0.6	0.9	1.2	-0.7	-1.1
Worrier / anxious feelings	0.6	1.1	2.2	0.0	1.5
Medication for pain relief, constipation, heartburn	0.6	1.1	2.2	0.1	-1.5
Chest pain or discomfort	0.6	0.8	0.9	-1.0	-0.8
Medication: Aspirin	0.6	0.8	0.9	1.0	0.8
Hearing aid user	0.6	0.7	1.3	1.1	0.4
Pain type(s) experienced in last month: Hip pain	0.6	0.7	1.4	-0.1	1.2
Number of operations (self-reported)	0.6	0.9	1.4	-0.5	-1.2
Vascular/heart problems diagnosed by doctor	0.6	1.8	2.9	-0.8	-1.7
Basal cell carcinoma (self-reported)	0.6	0.7	1.4	-0.0	-1.2
HbA1C	0.5	0.6	0.6	0.7	0.8
Neuroticism	0.5	1.2	2.1	-0.4	1.5
Medication: Metformin	0.5	0.7	1.3	0.4	1.1
Diabetes (father)	0.5	0.6	1.0	1.0	0.4
Current tobacco smoking	0.5	0.8	1.5	-0.2	1.2
Fed-up feelings	0.5	1.0	1.8	0.4	1.4
Nervous feelings	0.5	1.0	1.4	1.2	0.7
Glaucoma (self-reported)	0.5	0.6	0.7	-0.9	-0.7
Worry too long after embarrassment	0.5	0.9	1.6	0.3	1.3
Medication: Allopurinol	0.5	0.6	0.9	0.7	0.9
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.0	1.0	0.3
Hypertension (Self-reported)	0.5	1.4	2.3	0.7	1.5
Qualifications: nursing, teaching	0.5	0.8	1.2	-1.1	-0.7
Medication for cholesterol	0.5	0.7	1.3	-0.3	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.2	-1.1	-0.0
Smoking status: Current	0.5	0.8	1.6	-0.2	1.3
Supplements: Calcium	0.5	0.5	0.7	0.8	0.6
Lung FVC	0.4	2.2	3.9	2.0	0.7
Relative age of first facial hair	0.4	0.7	1.5	-0.1	-1.2
Medication for hormone replacement therapy	0.4	0.4	0.8	0.9	0.3
Impedance of leg (right)	0.4	1.9	2.6	1.6	1.1
Relative age voice broke	0.4	0.5	0.6	-0.7	-0.8
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.0	0.2	-1.0
Impedance of leg (left)	0.4	1.8	2.6	1.6	1.1
Number of incorrect matches in round	0.4	0.7	1.1	-0.5	1.1
Had menopause	0.4	0.5	0.8	0.4	0.9
Financial difficulties in last 2 years	0.4	0.5	0.7	-0.8	-0.7
Neuroticism score	0.4	0.8	1.6	-0.3	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	0.6	0.8	0.8
Pulse rate	0.4	0.8	1.5	-1.2	0.0
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.0	-0.2	1.0
Exposure to tobacco smoke at home	0.4	0.4	0.6	-0.4	0.8
Medication: Paracetamol	0.4	0.7	1.3	-1.1	-0.0
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.3	1.2	-0.2
High blood pressure (siblings)	0.4	0.6	1.0	1.0	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	0.9	-0.2	-1.0
Pulse wave peak to peak time	0.4	0.4	0.8	-0.9	-0.2
Medication: Blood pressure	0.4	0.8	1.5	0.1	1.2
Medication: Ibuprofen	0.4	0.4	0.6	-0.8	0.6
Pulse rate, automated reading	0.4	1.4	2.8	-1.7	-0.1
Comparative height size at age 10	0.4	2.2	4.2	2.0	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	1.0	1.0	-0.8
Handedness (chirality/laterality): Left-handed	0.4	0.5	0.5	-0.7	-0.7
Mood swings	0.4	0.7	1.1	-1.1	-0.4
Loneliness, isolation	0.4	0.6	1.0	-0.3	1.0
Medication: Aspirin	0.4	0.6	0.6	0.8	0.7
Wears glasses or contact lenses	0.4	0.4	0.8	-0.9	-0.3
Ever depressed for a whole week	0.4	0.5	0.5	-0.7	0.6
Worry (Nagel 2018)	0.3	0.6	1.2	0.3	1.1
Alzheimer’s Disease (in father)	0.3	0.3	0.4	0.5	0.7
Reaction Time	0.3	0.5	0.7	0.5	0.8
Crohns Disease (2012)	0.3	0.5	0.8	-0.9	-0.3
Neuroticism (2016)	0.3	0.4	0.5	-0.7	0.7
Number of treatments/medications taken	0.3	0.5	0.9	-1.0	-0.4
Systolic blood pressure, automated reading	0.3	1.0	1.9	-1.4	0.2
Angina	0.3	0.4	0.9	-0.0	0.9
Arm fat percentage (right)	0.3	1.1	2.1	-1.4	0.2
Medication: Cholesterol lowering	0.3	0.5	0.8	-0.9	0.3
Pulse wave Arterial Stiffness index	0.3	0.4	0.7	0.8	-0.0
Peak expiratory flow (PEF)	0.3	0.7	0.7	-0.9	-0.8
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	0.7	0.9	0.4
Blood clot in the leg (DVT)	0.3	0.4	0.7	-0.8	0.2
Medication: Amlodipine	0.3	0.5	0.9	1.0	0.2
Leg fat percentage (right)	0.3	1.1	1.6	-0.8	1.3
Health satisfaction	0.3	0.3	0.6	-0.3	-0.8
Neck or shoulder pain in last month	0.3	0.4	0.6	0.4	0.8
Medication: Omeprazole	0.3	0.3	0.5	-0.3	0.7
Mean time to correctly identify matches	0.3	0.5	0.9	-0.4	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	0.7	-0.4	0.8
Number of full sisters	0.3	0.3	0.6	0.8	-0.0
Suffer from ‘nerves’	0.3	0.4	0.7	0.4	0.9
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.5	0.7	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	0.7	-0.8	0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	0.5	0.7	0.7
Breast cancer (self-reported)	0.3	0.4	0.8	0.0	-0.9
Illnesses of father: None of the above (group 1)	0.3	0.3	0.5	-0.7	-0.4
Ever taken oral contraceptive pill	0.3	0.3	0.5	0.4	0.7
Medication: Paracetamol	0.3	0.5	0.9	-0.9	0.2
Leg fat percentage (left)	0.3	1.0	1.0	-1.0	1.0
Average weekly beer plus cider intake	0.3	0.4	0.5	-0.6	-0.7
Pack years of smoking	0.3	0.5	0.7	0.5	0.9
Bipolar Disorder (2018)	0.2	0.3	0.4	-0.4	-0.6
Depression (Nagel 2018)	0.2	0.2	0.4	-0.2	0.6
Age at First Birth	0.2	0.3	0.5	0.3	0.7
Rheumatoid Arthritis	0.2	0.2	0.3	-0.3	-0.6
Blood Platelet Count	0.2	2.0	4.1	0.1	2.0
BMI	0.2	1.0	1.9	-1.4	0.2
Type 2 Diabetes (T2D) (2018)	0.2	0.4	0.6	-0.4	-0.7
Average weekly spirits intake	0.2	0.2	0.3	0.5	0.5
Sensitivity / hurt feelings	0.2	0.4	0.5	-0.7	0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	0.4	0.7	-0.3
Vitamin and mineral supplements	0.2	0.2	0.2	-0.5	-0.4
Hand grip strength (right)	0.2	0.6	1.0	-1.0	0.3
Average weekly fortified wine intake	0.2	0.2	0.3	0.4	-0.5
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.3	-0.2	0.6
Medication: Atenolol	0.2	0.3	0.6	0.1	0.8
Leg predicted mass (left)	0.2	0.9	1.0	-1.0	-0.9
Alcohol usually taken with meals	0.2	0.3	0.5	-0.0	-0.7
Illnesses of mother	0.2	0.3	0.3	0.5	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	1.3	1.2	0.4
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.4	0.6	0.4
Forced vital capacity (FVC), Best measure	0.2	0.6	1.3	1.1	0.1
Body fat percentage	0.2	0.8	1.2	-1.1	0.6
Leg fat mass (right)	0.2	0.7	0.7	-0.9	0.8
Overall health rating	0.2	0.4	0.5	-0.7	-0.4
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.3	-0.6	-0.3
Whole body fat-free mass	0.2	1.0	1.4	-0.7	-1.2
Leg fat-free mass (right)	0.2	1.2	1.3	-1.1	-1.1
Arm fat percentage (left)	0.2	0.9	1.5	-1.2	0.4
Leg predicted mass (right)	0.2	1.3	1.4	-1.1	-1.2
Miserableness	0.2	0.4	0.8	-0.9	0.1
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.4	-0.7	0.2
Commuting to job workplace: Public transport	0.2	0.2	0.2	-0.4	0.5
Eye problems/disorders: Glaucoma	0.2	0.3	0.5	-0.0	0.7
High cholesterol (Self-reported)	0.2	0.3	0.6	-0.1	0.8
Age started oral contraceptive pill	0.2	0.3	0.5	0.3	0.7
Unable to work because of sickness or disability	0.2	0.2	0.3	0.6	-0.4
Cholesterol lowering medication	0.2	0.3	0.7	0.8	0.1
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.4	-0.3	0.6
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.4	-0.7	0.1
Impedance of whole body	0.2	0.9	1.5	1.2	0.5
Leg fat mass (left)	0.2	0.6	0.9	-1.0	0.6
Schizophrenia vs Biploar Disorder	0.1	0.1	0.1	-0.3	-0.3
Ulcerative Colitis (UC)	0.1	0.1	0.2	-0.4	-0.2
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.3	-0.4	-0.6
Body Mass Index (BMI) (2010)	0.1	0.1	0.2	0.2	-0.5
Fasting Glucose	0.1	0.1	0.1	0.3	-0.2
Lupus	0.1	0.1	0.3	0.1	0.5
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.1	0.4	0.4
Heel T-Score	0.1	1.0	1.0	1.0	1.0
Tanning	0.1	0.9	1.7	0.2	-1.3
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.3	-0.2	-0.5
Leg fat-free mass (left)	0.1	0.8	0.9	-0.9	-0.8
Trunk fat percentage	0.1	0.6	1.0	-1.0	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.1	0.3	0.2
Stomach or abdominal pain in last month	0.1	0.1	0.2	0.4	-0.0
Sitting height	0.1	1.0	1.7	1.3	-0.6
Body mass index (BMI)	0.1	0.6	1.2	-1.1	0.1
Trunk fat mass	0.1	0.5	1.0	-1.0	0.1
Past tobacco smoking	0.1	0.2	0.4	0.6	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.4	0.1	0.6
Medication: Simvastatin	0.1	0.1	0.1	-0.3	0.2
Trunk fat-free mass	0.1	0.7	1.3	-0.4	-1.1
Father’s age at death	0.1	0.1	0.1	0.4	-0.3
Falls in the last year	0.1	0.1	0.1	0.4	-0.1
Depression (self-reported)	0.1	0.1	0.2	0.2	0.4
Lung cancer (father)	0.1	0.1	0.2	-0.2	-0.4
Arm fat mass (right)	0.1	0.5	1.1	-1.0	0.0
Trunk predicted mass	0.1	0.8	1.4	-0.5	-1.2
Standing height	0.1	1.0	1.3	1.1	-0.8
Tense / ‘highly strung’	0.1	0.1	0.1	-0.4	0.3
Headache pain in last month	0.1	0.2	0.3	-0.1	0.6
Birth weight	0.1	0.2	0.4	0.2	0.6
Exposure to tobacco smoke outside home	0.1	0.2	0.3	-0.2	-0.6
Eye problems/disorders: None of the above	0.1	0.1	0.1	-0.1	0.4
Angina (self-reported)	0.1	0.2	0.3	-0.0	0.6
Whole body fat mass	0.1	0.4	0.6	-0.8	0.5
Illnesses of father: Heart disease	0.1	0.1	0.2	-0.0	-0.4
Smoking status: Previous	0.1	0.2	0.3	-0.2	0.6
Average weekly red wine intake	0.1	0.2	0.2	-0.4	-0.5
Ever had bowel cancer screening	0.1	0.1	0.2	-0.5	0.0
Friendships satisfaction	0.1	0.2	0.2	0.5	0.3
Back pain experienced in last month	0.1	0.1	0.1	-0.3	0.3
Osteoporosis (self-reported)	0.1	0.1	0.2	-0.5	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.1	0.1	0.4	0.3
Whole body water mass	0.1	0.8	1.0	-0.7	-1.0
Arm fat mass (left)	0.1	0.4	0.8	-0.9	0.2
Mother’s age at death	0.1	0.1	0.1	0.3	0.2
Medication: Blood pressure	0.1	0.2	0.3	0.5	0.3
Ever smoked	0.1	0.1	0.2	0.2	0.5
Basal metabolic rate	0.1	0.4	0.5	-0.6	-0.7
Diastolic blood pressure, automated reading	0.1	0.4	0.5	-0.5	0.7
Intelligence (Savage-Jansen 2018)	0.0	0.0	0.0	0.1	-0.2
Crohns Disease (2017)	0.0	0.1	0.1	-0.3	-0.3
Irritable Bowel Disease (IBD)	0.0	0.1	0.1	-0.2	-0.3
Breast Cancer	0.0	0.0	0.0	-0.0	0.0
Blood Red Count	0.0	0.4	0.5	-0.7	0.4
Height	0.0	0.7	1.3	1.1	0.2
Waist Hip Ratio (WHR)	0.0	0.2	0.4	0.6	0.2
Systolic Blood Pressure	0.0	0.1	0.1	-0.4	0.0
Cardiovascular Disease	0.0	0.1	0.1	-0.2	-0.3
Hypothyroidism (self reported)	0.0	0.0	0.0	0.2	-0.0
Hair Pigment	0.0	0.0	0.1	0.0	0.2
Hand grip strength (left)	0.0	0.1	0.1	-0.2	0.3
Hearing difficulty/problems: Yes	0.0	0.1	0.1	-0.1	0.4
Medication: Levothyroxine sodium	0.0	0.0	0.1	-0.1	-0.2
Waist circumference	0.0	0.1	0.2	-0.5	0.1
Hearing difficulty/problems with background noise	0.0	0.0	0.0	0.0	0.0
Diabetes (self-reported)	0.0	0.1	0.1	0.3	0.1
Illnesses of siblings	0.0	0.0	0.1	-0.0	0.2
Weight	0.0	0.1	0.2	-0.5	-0.2
Impedance of arm (right)	0.0	0.2	0.3	0.1	-0.6
Hip circumference	0.0	0.0	0.0	-0.2	-0.1
Prospective memory result	0.0	0.1	0.1	0.2	0.3
Impedance of arm (left)	0.0	0.1	0.1	0.4	-0.1
Breastfed as a baby	0.0	0.0	0.0	-0.1	-0.1
Hypothyroidism/myxoedema (self-reported)	0.0	0.1	0.1	-0.3	-0.2
Arm fat-free mass (right)	0.0	0.0	0.1	0.3	-0.1
Heart disease (mother)	0.0	0.1	0.1	-0.3	-0.1
Arm predicted mass (right)	0.0	0.0	0.1	-0.1	-0.3
Diabetes diagnosed by doctor	0.0	0.1	0.1	0.2	-0.4
Medication: Gliclazide	0.0	0.0	0.0	-0.1	0.1
Arm fat-free mass (left)	0.0	0.1	0.3	-0.1	-0.5
Risk taking	0.0	0.1	0.1	-0.3	0.1
Arm predicted mass (left)	0.0	0.2	0.4	-0.1	-0.6

Hub : Genes

IL4R

Models

Trait associations