[Hub]/) : Traits : Hayfever, allergic rhinitis or eczema :

chr4:122,377,715-124,935,698

Best TWAS P=1.71e-35 · Best GWAS P=9.65e-30 conditioned to 0.153

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KIAA1109 0.09 0.08 bslmm 390 0.08 8.9e-10 11.0 -7.9 2.3e-15 -0.68 0.04 0.96 FALSE
2 GTEx Artery Aorta KIAA1109 0.11 0.00 lasso 7 0.01 5.1e-02 11.2 -9.3 1.5e-20 -0.65 0.06 0.63 FALSE
3 GTEx Artery Tibial KIAA1109 0.16 0.07 lasso 6 0.05 5.1e-05 10.7 -10.4 2.7e-25 -0.79 0.03 0.95 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia KIAA1109 0.22 0.07 lasso 7 0.03 5.9e-02 10.7 -10.5 8.7e-26 -0.71 0.04 0.44 FALSE
5 GTEx Colon Transverse KIAA1109 0.25 -0.01 enet 16 0.00 4.1e-01 10.9 -11.1 1.6e-28 -0.92 0.02 0.77 TRUE
6 ROSMAP Brain Pre-frontal Cortex KIAA1109 0.08 0.08 lasso 7 0.07 2.5e-09 10.7 -10.5 1.4e-25 -0.79 0.04 0.96 FALSE
7 ROSMAP Brain Pre-frontal Cortex SPATA5 0.05 0.01 bslmm 485 0.01 1.2e-02 3.8 -7.4 1.1e-13 -0.12 0.16 0.06 TRUE
8 The Cancer Genome Atlas Breast Invasive Carcinoma KIAA1109 0.03 0.03 lasso 1 0.02 1.2e-05 10.7 -10.7 9.1e-27 -0.77 0.16 0.75 FALSE
9 The Cancer Genome Atlas Esophageal Carcinoma KIAA1109 0.32 0.02 blup 45 0.02 7.4e-02 10.9 -12.4 1.7e-35 -0.51 0.01 0.46 TRUE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma KIAA1109 0.05 0.05 enet 8 0.04 1.3e-05 10.7 -8.1 7.7e-16 -0.80 0.02 0.94 TRUE
11 The Cancer Genome Atlas Brain Lower Grade Glioma KIAA1109 0.06 0.05 lasso 2 0.03 7.1e-05 10.7 -11.0 6.1e-28 -0.79 0.31 0.53 TRUE
12 The Cancer Genome Atlas Thyroid Carcinoma KIAA1109 0.05 0.04 enet 3 0.05 5.4e-06 10.9 -11.4 2.5e-30 -0.90 0.01 0.98 FALSE