Best TWAS P=6.42e-11 · Best GWAS P=9.48e-10 conditioned to 0.761
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 6 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | NFKB1 | 0.10 | 0.06 | blup | 90 | 0.07 | 2.2e-03 | -5.8 | 6.5 | 6.4e-11 | -0.92 | 0.03 | 0.91 | TRUE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | NFKB1 | 0.06 | 0.09 | enet | 7 | 0.09 | 9.1e-09 | -5.8 | -5.8 | 5.4e-09 | 0.97 | 0.03 | 0.97 | FALSE |
| 5 | YFS | Blood | NFKB1 | 0.04 | 0.03 | lasso | 6 | 0.03 | 5.4e-09 | -5.7 | -5.7 | 1.1e-08 | 0.98 | 0.03 | 0.97 | FALSE |
| 3 | METSIM | Adipose | SLC9B1 | 0.02 | 0.03 | lasso | 8 | 0.02 | 1.2e-04 | -5.5 | -5.5 | 4.3e-08 | 0.46 | 0.22 | 0.68 | FALSE |
| 4 | YFS | Blood | MANBA | 0.09 | 0.10 | lasso | 3 | 0.10 | 5.2e-30 | -5.4 | -5.4 | 5.3e-08 | 0.46 | 0.30 | 0.70 | FALSE |
| 2 | GTEx | Pancreas | MANBA | 0.14 | 0.14 | enet | 5 | 0.06 | 1.8e-03 | -5.4 | 5.4 | 5.9e-08 | -0.46 | 0.24 | 0.61 | FALSE |
| 1 | CommonMind | Brain Pre-frontal Cortex | MANBA | 0.08 | 0.04 | bslmm | 390 | 0.03 | 9.6e-05 | 4.1 | -5.4 | 6.0e-08 | 0.45 | 0.77 | 0.19 | FALSE |