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chr12:111,154,626-113,517,494

Best TWAS P=1.37e-11 · Best GWAS P=9.83e-16 conditioned to 1.57e-06

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	YFS	Blood	SH2B3	0.05	0.01	enet	22	0.02	3.3e-07	-5.4	6.8	1.4e-11	0.64	0.57	0.43	TRUE
6	GTEx	Artery Tibial	HECTD4	0.05	0.02	lasso	3	0.01	3.1e-02	5.9	6.1	9.8e-10	0.78	0.01	0.93	FALSE
9	GTEx	Skin Sun Exposed Lower leg	ALDH2	0.10	0.09	enet	13	0.13	6.7e-11	-4.0	5.7	1.5e-08	0.62	0.97	0.03	FALSE
7	GTEx	Brain Frontal Cortex BA9	ALDH2	0.33	0.04	enet	24	0.09	2.0e-03	-4.0	5.5	2.9e-08	0.33	0.09	0.08	FALSE
10	GTEx	Thyroid	BRAP	0.07	0.02	lasso	7	0.03	1.1e-03	-5.4	-5.5	3.5e-08	-0.54	0.29	0.53	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ATXN2	0.02	0.03	enet	8	0.02	4.8e-04	-4.0	5.5	4.8e-08	0.56	0.26	0.65	FALSE
13	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ERP29	0.11	0.03	blup	25	0.05	5.0e-03	-4.3	-5.4	5.3e-08	-0.60	0.01	0.75	FALSE
5	GTEx	Artery Aorta	AC003029.1	0.07	0.01	lasso	7	0.01	5.4e-02	-5.7	-5.3	1.1e-07	-0.43	0.22	0.19	FALSE
11	GTEx	Thyroid	ALDH2	0.06	0.04	lasso	4	0.05	9.7e-05	-5.7	5.3	1.2e-07	0.47	0.88	0.06	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	MAPKAPK5-AS1	0.04	0.00	enet	30	0.00	7.0e-01	-4.5	-5.2	1.5e-07	-0.53	0.22	0.13	FALSE
2	GTEx	Adipose Subcutaneous	HECTD4	0.06	0.00	enet	15	0.02	1.0e-02	-4.4	5.2	1.7e-07	0.65	0.06	0.85	FALSE
4	GTEx	Adipose Subcutaneous	AC003029.1	0.08	0.07	enet	30	0.05	1.2e-04	-4.4	-5.2	1.7e-07	-0.47	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	MAPKAPK5-AS1	0.08	0.01	enet	26	0.03	2.1e-03	-5.4	-5.2	2.5e-07	-0.44	0.97	0.02	FALSE