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chr17:42,607,368-43,913,030

Best TWAS P=1.25e-08 · Best GWAS P=3.14e-07 conditioned to 0.976

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cerebellar Hemisphere	FMNL1	0.27	0.03	enet	17	0.09	2.2e-03	-5.0	5.7	1.2e-08	-0.50	0.00	0.71	TRUE
10	GTEx	Skin Not Sun Exposed Suprapubic	LRRC37A4P	0.45	0.47	enet	34	0.50	6.3e-31	-4.9	5.7	1.6e-08	-0.84	0.02	0.98	TRUE
11	GTEx	Thyroid	LRRC37A4P	0.56	0.56	enet	52	0.60	6.3e-57	-4.9	5.4	7.7e-08	-0.80	0.02	0.98	FALSE
7	GTEx	Colon Sigmoid	MAPT	0.12	0.18	enet	18	0.17	1.1e-06	-4.8	5.4	8.4e-08	-0.87	0.02	0.98	FALSE
2	GTEx	Brain Cerebellum	PLEKHM1	0.41	0.44	enet	19	0.45	6.8e-15	-4.8	5.3	9.9e-08	-0.82	0.02	0.98	FALSE
9	GTEx	Muscle Skeletal	PLEKHM1	0.08	0.09	enet	15	0.09	7.8e-09	-5.0	-5.3	1.0e-07	0.97	0.01	0.99	FALSE
3	GTEx	Brain Cortex	LRRC37A4P	0.51	0.38	lasso	12	0.36	7.0e-11	-4.8	5.2	1.5e-07	-0.93	0.01	0.98	FALSE
8	GTEx	Esophagus Mucosa	LRRC37A4P	0.36	0.26	lasso	8	0.27	4.0e-18	-4.9	5.2	1.6e-07	-0.89	0.02	0.98	FALSE
5	GTEx	Breast Mammary Tissue (Female)	CRHR1	0.25	0.28	lasso	11	0.28	3.7e-09	-4.9	-5.2	1.9e-07	0.86	0.02	0.98	FALSE
6	GTEx	Cells Transformed fibroblasts	CRHR1-IT1	0.49	0.71	enet	23	0.71	2.3e-75	-4.9	-5.2	2.5e-07	0.89	0.02	0.98	FALSE
4	GTEx	Breast Mammary Tissue	CRHR1	0.14	0.18	enet	14	0.20	2.0e-10	-4.9	-5.1	3.0e-07	0.93	0.02	0.98	FALSE