[Hub]/) : Traits : Medication: Blood pressure : ← →

chr17:42,607,368-43,913,030

Best TWAS P=1.25e-08 · Best GWAS P=3.14e-07 conditioned to 0.976

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere FMNL1 0.27 0.03 enet 17 0.09 2.2e-03 -5.0 5.7 1.2e-08 -0.50 0.00 0.71 TRUE
2 GTEx Brain Cerebellum PLEKHM1 0.41 0.44 enet 19 0.45 6.8e-15 -4.8 5.3 9.9e-08 -0.82 0.02 0.98 FALSE
3 GTEx Brain Cortex LRRC37A4P 0.51 0.38 lasso 12 0.36 7.0e-11 -4.8 5.2 1.5e-07 -0.93 0.01 0.98 FALSE
4 GTEx Breast Mammary Tissue CRHR1 0.14 0.18 enet 14 0.20 2.0e-10 -4.9 -5.1 3.0e-07 0.93 0.02 0.98 FALSE
5 GTEx Breast Mammary Tissue (Female) CRHR1 0.25 0.28 lasso 11 0.28 3.7e-09 -4.9 -5.2 1.9e-07 0.86 0.02 0.98 FALSE
6 GTEx Cells Transformed fibroblasts CRHR1-IT1 0.49 0.71 enet 23 0.71 2.3e-75 -4.9 -5.2 2.5e-07 0.89 0.02 0.98 FALSE
7 GTEx Colon Sigmoid MAPT 0.12 0.18 enet 18 0.17 1.1e-06 -4.8 5.4 8.4e-08 -0.87 0.02 0.98 FALSE
8 GTEx Esophagus Mucosa LRRC37A4P 0.36 0.26 lasso 8 0.27 4.0e-18 -4.9 5.2 1.6e-07 -0.89 0.02 0.98 FALSE
9 GTEx Muscle Skeletal PLEKHM1 0.08 0.09 enet 15 0.09 7.8e-09 -5.0 -5.3 1.0e-07 0.97 0.01 0.99 FALSE
10 GTEx Skin Not Sun Exposed Suprapubic LRRC37A4P 0.45 0.47 enet 34 0.50 6.3e-31 -4.9 5.7 1.6e-08 -0.84 0.02 0.98 TRUE
11 GTEx Thyroid LRRC37A4P 0.56 0.56 enet 52 0.60 6.3e-57 -4.9 5.4 7.7e-08 -0.80 0.02 0.98 FALSE