Best TWAS P=9.36e-08 · Best GWAS P=1.18e-06 conditioned to 0.184
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Prostate | NSF | 0.20 | -0.01 | lasso | 12 | -0.01 | 7.0e-01 | -4.4 | 5.3 | 9.4e-08 | -0.74 | 0.01 | 0.31 | TRUE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | LRRC37A2 | 0.27 | 0.36 | enet | 25 | 0.40 | 1.5e-50 | -4.3 | -5.2 | 2.2e-07 | 0.81 | 0.04 | 0.91 | FALSE |
3 | The Cancer Genome Atlas | Soft Tissue Sarcoma | LRRC37A2 | 0.43 | 0.26 | enet | 22 | 0.37 | 3.8e-23 | -4.4 | -5.2 | 1.8e-07 | 0.72 | 0.04 | 0.91 | FALSE |