TWAS
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Traits
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chr17:44,788,310-45,510,971
Best TWAS P=9.36e-08 · Best GWAS P=1.18e-06 conditioned to 0.184
44.8M
44.9M
45M
45.1M
45.2M
45.3M
45.4M
45.5M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Prostate
NSF
0.20
-0.01
lasso
12
-0.01
7.0e-01
-4.4
5.3
9.4e-08
-0.74
0.01
0.31
TRUE
3
The Cancer Genome Atlas
Soft Tissue Sarcoma
LRRC37A2
0.43
0.26
enet
22
0.37
3.8e-23
-4.4
-5.2
1.8e-07
0.72
0.04
0.91
FALSE
2
The Cancer Genome Atlas
Lung Adenocarcinoma
LRRC37A2
0.27
0.36
enet
25
0.40
1.5e-50
-4.3
-5.2
2.2e-07
0.81
0.04
0.91
FALSE