Best TWAS P=2.76e-08 · Best GWAS P=5.7e-08 conditioned to 0.719
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | LSMD1 | 0.28 | 0.12 | lasso | 5 | 0.19 | 3.3e-09 | 4.6 | 5.4 | 6.1e-08 | 0.84 | 0.02 | 0.98 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | FGF11 | 0.08 | 0.04 | blup | 454 | 0.04 | 1.2e-05 | 3.1 | -5.6 | 2.8e-08 | -0.16 | 0.61 | 0.20 | TRUE |
| 3 | YFS | Blood | CYB5D1 | 0.28 | 0.19 | bslmm | 488 | 0.24 | 5.9e-79 | 4.9 | -5.4 | 5.8e-08 | -0.80 | 0.02 | 0.98 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | TNFSF12-TNFSF13 | 0.03 | 0.00 | lasso | 4 | 0.01 | 2.9e-02 | 4.7 | 5.5 | 2.8e-08 | 0.11 | 0.01 | 0.34 | FALSE |