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chr11:115,953,897-117,745,003
Best TWAS P=4.71e-14 · Best GWAS P=4.06e-15 conditioned to 0.854
116M
116.5M
117M
117.5M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
ZNF259
0.08
0.03
enet
6
0.03
0.00012
-5.6
7.5
4.7e-14
-0.76
0.02
0.97
TRUE
4
The Cancer Genome Atlas
Ovarian Serous Cystadenocarcinoma
BUD13
0.08
0.00
blup
76
0.01
0.09230
1.1
5.9
4.1e-09
-0.22
0.02
0.04
TRUE
2
GTEx
Cells Transformed fibroblasts
PAFAH1B2
0.11
0.00
lasso
3
0.00
0.13000
-5.0
5.5
4.7e-08
-0.42
0.06
0.21
TRUE
3
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
ZNF259
0.04
0.03
lasso
3
0.02
0.00084
-6.3
6.3
3.1e-10
-0.48
0.19
0.08
FALSE