Best TWAS P=4.71e-14 · Best GWAS P=4.06e-15 conditioned to 0.854
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ZNF259 | 0.08 | 0.03 | enet | 6 | 0.03 | 0.00012 | -5.6 | 7.5 | 4.7e-14 | -0.76 | 0.02 | 0.97 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | PAFAH1B2 | 0.11 | 0.00 | lasso | 3 | 0.00 | 0.13000 | -5.0 | 5.5 | 4.7e-08 | -0.42 | 0.06 | 0.21 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | ZNF259 | 0.04 | 0.03 | lasso | 3 | 0.02 | 0.00084 | -6.3 | 6.3 | 3.1e-10 | -0.48 | 0.19 | 0.08 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | BUD13 | 0.08 | 0.00 | blup | 76 | 0.01 | 0.09230 | 1.1 | 5.9 | 4.1e-09 | -0.22 | 0.02 | 0.04 | TRUE |