Best TWAS P=2.02e-17 · Best GWAS P=9.33e-17 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | ARHGAP42 | 0.22 | 0.15 | enet | 18 | 0.19 | 1.7e-10 | -8.3 | -7.8 | 4.4e-15 | 0.85 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Aorta | TMEM133 | 0.30 | 0.15 | enet | 34 | 0.19 | 7.1e-11 | -8.3 | -6.6 | 5.1e-11 | 0.70 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Artery Tibial | ARHGAP42 | 0.24 | 0.24 | lasso | 4 | 0.24 | 2.4e-18 | -8.3 | -8.5 | 2.0e-17 | 0.97 | 0.00 | 1.00 | TRUE |
| 4 | GTEx | Artery Tibial | TMEM133 | 0.26 | 0.25 | enet | 28 | 0.27 | 1.3e-21 | -8.3 | -8.5 | 2.3e-17 | 0.91 | 0.00 | 1.00 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ARHGAP42 | 0.04 | 0.01 | blup | 266 | 0.02 | 1.1e-04 | 4.3 | -6.1 | 8.4e-10 | 0.52 | 0.05 | 0.87 | FALSE |