[Hub]/) : Traits : BMI : →

chr1:752,566-3,407,007

Best TWAS P=4.18e-23 · Best GWAS P=4.99e-15 conditioned to 0.0128

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	C1orf86	0.15	0.05	enet	10	0.04	2.0e-04	-2.40	-5.4	7.8e-08	-0.07	0.28	0.38	FALSE
2	GTEx	Adipose Subcutaneous	SLC35E2B	0.47	0.16	lasso	7	0.32	1.6e-26	-7.41	7.1	1.2e-12	0.04	0.01	0.99	FALSE
3	GTEx	Adipose Subcutaneous	RP1-283E3.4	0.65	0.14	lasso	9	0.33	5.1e-28	-7.41	-9.1	6.3e-20	0.00	0.01	0.99	FALSE
4	GTEx	Adipose Subcutaneous	RP11-345P4.10	0.60	0.17	enet	27	0.34	2.7e-28	-7.41	7.8	7.1e-15	0.02	0.01	0.99	FALSE
5	GTEx	Adipose Visceral Omentum	CALML6	0.13	0.03	lasso	5	0.03	1.6e-02	-5.78	-5.7	9.5e-09	0.00	0.21	0.05	FALSE
6	GTEx	Adipose Visceral Omentum	RP1-283E3.4	0.26	0.05	enet	25	0.16	1.5e-08	-7.41	-9.9	6.3e-23	-0.02	0.01	0.92	FALSE
7	GTEx	Adipose Visceral Omentum	RP11-345P4.10	0.28	0.12	enet	18	0.27	1.9e-14	-7.41	7.4	1.8e-13	0.02	0.01	0.98	FALSE
8	GTEx	Artery Aorta	SLC35E2B	0.51	0.12	enet	39	0.26	1.9e-14	2.12	5.5	2.9e-08	0.03	0.04	0.96	FALSE
9	GTEx	Artery Aorta	RP1-283E3.4	0.60	0.12	lasso	9	0.27	3.2e-15	-7.41	-9.1	6.1e-20	-0.01	0.01	0.98	FALSE
10	GTEx	Artery Aorta	RP11-345P4.10	0.62	0.15	enet	34	0.28	1.9e-15	-7.41	6.3	3.9e-10	0.03	0.01	0.99	FALSE
11	GTEx	Artery Coronary	AL645728.2	0.18	0.03	lasso	3	0.00	4.2e-01	-5.31	-5.8	6.3e-09	-0.01	0.04	0.16	FALSE
12	GTEx	Artery Tibial	SLC35E2B	0.44	0.14	enet	29	0.24	7.6e-19	-7.41	6.8	1.5e-11	0.03	0.01	0.99	FALSE
13	GTEx	Artery Tibial	RP1-283E3.4	0.66	0.09	lasso	6	0.38	4.9e-31	-7.41	-8.4	4.5e-17	0.01	0.01	0.99	FALSE
14	GTEx	Artery Tibial	RP11-345P4.10	0.61	0.10	lasso	10	0.36	3.1e-29	-7.41	8.3	8.0e-17	0.01	0.01	0.99	FALSE
15	GTEx	Brain Cerebellar Hemisphere	NADK	0.18	0.11	lasso	7	0.09	3.1e-03	-6.77	-6.9	5.1e-12	0.03	0.06	0.33	FALSE
16	GTEx	Brain Cerebellar Hemisphere	RP5-890O3.9	0.24	0.02	lasso	9	0.02	1.3e-01	-7.05	6.6	3.1e-11	-0.01	0.04	0.32	FALSE
17	GTEx	Brain Cerebellum	TNFRSF14	0.17	0.07	enet	6	0.10	7.6e-04	5.56	5.6	2.6e-08	-0.66	0.15	0.26	FALSE
18	GTEx	Brain Cerebellum	RP3-395M20.8	0.19	0.05	enet	8	0.06	5.9e-03	3.65	5.3	1.4e-07	-0.66	0.17	0.18	FALSE
19	GTEx	Brain Putamen basal ganglia	RP11-345P4.9	0.32	0.21	lasso	3	0.13	4.5e-04	4.14	6.3	2.6e-10	0.04	0.06	0.10	FALSE
20	GTEx	Cells Transformed fibroblasts	SLC35E2B	0.47	0.17	lasso	12	0.23	3.3e-17	-7.41	7.6	2.8e-14	0.02	0.01	0.99	FALSE
21	GTEx	Cells Transformed fibroblasts	RP1-283E3.4	0.59	0.13	lasso	8	0.29	3.0e-22	3.35	-9.0	2.1e-19	0.01	0.54	0.46	FALSE
22	GTEx	Cells Transformed fibroblasts	RP11-345P4.10	0.66	0.17	lasso	13	0.32	7.5e-25	-7.41	8.1	4.3e-16	0.00	0.01	0.99	FALSE
23	GTEx	Esophagus Mucosa	TMEM52	0.17	0.18	lasso	2	0.20	2.9e-13	-7.60	7.6	3.4e-14	0.02	0.00	1.00	TRUE
24	GTEx	Esophagus Mucosa	SLC35E2B	0.33	0.17	enet	12	0.22	5.6e-15	-7.41	6.8	8.2e-12	0.05	0.01	0.99	FALSE
25	GTEx	Esophagus Mucosa	RP1-283E3.4	0.53	0.12	enet	20	0.22	4.1e-15	-7.41	-9.7	5.1e-22	0.02	0.01	0.99	FALSE
26	GTEx	Esophagus Muscularis	SLC35E2B	0.41	0.20	enet	25	0.30	1.2e-18	-7.41	7.0	2.8e-12	0.03	0.01	0.99	FALSE
27	GTEx	Esophagus Muscularis	RP1-283E3.4	0.46	0.14	enet	23	0.24	1.6e-14	-7.41	-9.9	4.2e-23	0.01	0.01	0.99	TRUE
28	GTEx	Esophagus Muscularis	RP11-345P4.10	0.55	0.20	lasso	9	0.35	6.5e-22	-7.41	7.8	6.4e-15	0.01	0.01	0.99	FALSE
29	GTEx	Esophagus Muscularis	RP3-395M20.12	0.08	0.06	enet	6	0.06	2.3e-04	5.56	-8.1	7.5e-16	0.78	0.01	0.98	TRUE
30	GTEx	Heart Atrial Appendage	NADK	0.19	0.00	lasso	5	0.00	3.1e-01	-6.53	-6.1	9.0e-10	0.04	0.04	0.20	FALSE
31	GTEx	Heart Atrial Appendage	SLC35E2B	0.22	0.01	lasso	5	0.03	2.6e-02	-7.41	7.8	5.0e-15	0.03	0.03	0.27	FALSE
32	GTEx	Heart Atrial Appendage	RP11-345P4.10	0.36	0.11	enet	15	0.16	1.1e-07	-7.41	8.6	1.2e-17	-0.01	0.02	0.85	FALSE
33	GTEx	Lung	NADK	0.07	0.03	lasso	3	0.02	8.5e-03	6.75	-7.0	1.9e-12	0.01	0.09	0.74	FALSE
34	GTEx	Lung	SLC35E2B	0.31	0.15	lasso	9	0.16	6.6e-12	-7.41	6.5	1.0e-10	0.04	0.01	0.99	FALSE
35	GTEx	Lung	RP1-283E3.4	0.58	0.07	lasso	7	0.34	8.8e-27	-7.41	-8.6	1.0e-17	0.02	0.02	0.98	FALSE
36	GTEx	Lung	RP11-345P4.10	0.50	0.20	lasso	7	0.30	2.2e-23	-7.41	7.5	6.3e-14	0.00	0.01	0.99	FALSE
37	GTEx	Muscle Skeletal	NADK	0.06	0.00	enet	9	0.00	1.3e-01	-6.77	-7.5	7.6e-14	0.00	0.02	0.95	FALSE
38	GTEx	Muscle Skeletal	TMEM52	0.11	0.08	lasso	6	0.10	7.2e-10	-7.27	7.5	8.8e-14	-0.02	0.02	0.98	FALSE
39	GTEx	Muscle Skeletal	SLC35E2B	0.35	0.06	lasso	4	0.19	3.2e-18	-7.41	9.0	3.4e-19	0.01	0.01	0.99	FALSE
40	GTEx	Muscle Skeletal	RP1-283E3.4	0.51	0.12	lasso	6	0.29	2.4e-28	-7.41	-8.6	1.2e-17	0.01	0.01	0.99	FALSE
41	GTEx	Muscle Skeletal	RP11-345P4.10	0.54	0.06	lasso	7	0.29	4.7e-29	-7.41	8.5	1.9e-17	0.00	0.02	0.98	FALSE
42	GTEx	Nerve Tibial	CALML6	0.13	0.12	lasso	2	0.11	4.4e-08	-5.70	-5.8	8.7e-09	0.00	1.00	0.00	FALSE
43	GTEx	Nerve Tibial	SLC35E2B	0.19	0.09	lasso	7	0.08	2.5e-06	-7.41	8.3	7.3e-17	0.01	0.01	0.99	FALSE
44	GTEx	Pancreas	TNFRSF14	0.13	0.04	enet	8	0.04	1.0e-02	5.56	6.7	1.9e-11	-0.63	0.49	0.21	FALSE
45	GTEx	Pancreas	CALML6	0.21	0.08	lasso	4	0.06	2.2e-03	-5.78	-5.8	8.8e-09	0.00	0.32	0.36	FALSE
46	GTEx	Pituitary	NADK	0.21	0.09	enet	15	0.07	9.5e-03	-7.27	-5.8	6.0e-09	-0.02	0.02	0.68	FALSE
47	GTEx	Skin Not Sun Exposed Suprapubic	TMEM52	0.19	0.18	lasso	4	0.14	2.6e-08	6.75	7.1	1.4e-12	-0.01	0.11	0.89	FALSE
48	GTEx	Skin Not Sun Exposed Suprapubic	RP1-283E3.4	0.48	0.12	lasso	5	0.31	1.1e-17	-7.41	-9.2	3.5e-20	0.01	0.01	0.98	FALSE
49	GTEx	Skin Sun Exposed Lower leg	TMEM52	0.17	0.14	lasso	7	0.15	2.0e-12	7.09	7.5	5.5e-14	-0.01	0.04	0.96	FALSE
50	GTEx	Skin Sun Exposed Lower leg	SLC35E2B	0.43	0.07	enet	21	0.26	9.4e-22	-0.18	6.5	8.1e-11	0.06	0.08	0.92	FALSE
51	GTEx	Skin Sun Exposed Lower leg	RP11-345P4.10	0.58	0.08	enet	26	0.35	6.6e-30	3.35	7.2	6.2e-13	0.02	0.09	0.91	FALSE
52	GTEx	Spleen	TMEM52	0.47	0.21	lasso	5	0.22	2.3e-06	-5.31	-6.0	2.6e-09	0.01	0.31	0.20	FALSE
53	GTEx	Spleen	RP3-395M20.9	0.42	0.14	lasso	3	0.15	1.1e-04	-6.93	-6.9	4.8e-12	0.59	0.06	0.62	FALSE
54	GTEx	Thyroid	SLC35E2B	0.50	0.18	lasso	14	0.24	2.1e-18	-7.41	7.1	1.5e-12	0.05	0.01	0.99	FALSE
55	GTEx	Thyroid	RP1-283E3.4	0.59	0.04	lasso	10	0.22	3.8e-17	-7.41	-9.2	2.9e-20	0.00	0.01	0.98	FALSE
56	GTEx	Thyroid	RP11-345P4.10	0.66	0.21	lasso	17	0.39	1.5e-31	-7.41	7.8	5.7e-15	0.01	0.01	0.99	FALSE
57	GTEx	Whole Blood	FAM213B	0.06	0.00	lasso	3	0.00	6.5e-01	-5.98	-5.9	3.4e-09	0.55	0.10	0.09	FALSE
58	GTEx	Whole Blood	RP11-345P4.10	0.36	0.10	enet	29	0.19	6.9e-17	-7.41	6.9	3.9e-12	0.03	0.01	0.99	FALSE
59	METSIM	Adipose	TNFRSF14	0.07	0.05	blup	373	0.05	1.9e-07	5.67	6.0	2.4e-09	-0.63	0.81	0.18	FALSE
60	ROSMAP	Brain Pre-frontal Cortex	C1orf222	0.11	0.14	enet	18	0.14	1.8e-17	-5.11	6.2	6.0e-10	-0.02	0.99	0.01	FALSE
61	ROSMAP	Brain Pre-frontal Cortex	MMP23B	0.05	0.04	lasso	2	0.03	1.9e-04	-7.05	-7.0	1.9e-12	0.02	0.02	0.97	FALSE
62	ROSMAP	Brain Pre-frontal Cortex	TTC34	0.09	0.03	enet	21	0.07	5.7e-09	3.35	6.0	2.4e-09	-0.52	0.98	0.02	FALSE
63	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC35E2	0.03	0.03	blup	35	0.01	7.0e-02	-6.61	-5.1	3.0e-07	0.04	0.01	0.98	FALSE
64	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TMEM52	0.02	0.01	blup	37	0.02	6.6e-03	-7.53	7.1	9.9e-13	-0.02	0.01	0.84	FALSE
65	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC35E2	0.03	0.00	blup	34	0.01	5.3e-02	-6.68	6.3	2.5e-10	-0.02	0.01	0.70	FALSE
66	The Cancer Genome Atlas	Brain Lower Grade Glioma	SLC35E2	0.04	0.03	lasso	5	0.05	1.4e-06	-6.68	5.1	2.9e-07	-0.04	0.02	0.98	FALSE
67	The Cancer Genome Atlas	Testicular Germ Cell Tumors	TNFRSF14	0.18	0.02	blup	52	0.10	2.4e-04	4.16	6.7	1.6e-11	-0.68	0.02	0.22	FALSE