[Hub]/) : Traits : BMI : ← →

chr1:39,182,130-40,737,589

Best TWAS P=6.1e-17 · Best GWAS P=2.03e-15 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	BMP8A	0.05	0.03	lasso	3	0.02	8.8e-04	6.88	7.1	1.2e-12	0.78	0.04	0.93	FALSE
2	GTEx	Adipose Subcutaneous	PABPC4	0.15	0.04	lasso	8	0.04	3.3e-04	2.85	-5.8	7.3e-09	-0.87	0.03	0.97	FALSE
3	GTEx	Adipose Subcutaneous	RP11-69E11.4	0.14	0.08	enet	22	0.10	1.4e-08	6.79	5.5	3.6e-08	0.66	0.97	0.03	FALSE
4	GTEx	Adipose Subcutaneous	BMP8A	0.06	0.05	lasso	1	0.04	3.5e-04	6.69	6.7	2.2e-11	0.51	0.15	0.23	FALSE
5	GTEx	Adipose Visceral Omentum	RP11-69E11.4	0.10	0.07	lasso	2	0.07	1.3e-04	6.00	5.3	9.1e-08	0.53	0.24	0.69	TRUE
6	GTEx	Adrenal Gland	PABPC4	0.20	0.09	lasso	8	0.06	3.0e-03	6.79	-8.4	6.1e-17	-0.83	0.03	0.90	TRUE
7	GTEx	Adrenal Gland	RP11-69E11.4	0.11	0.05	lasso	3	0.00	2.4e-01	6.69	7.5	6.7e-14	0.58	0.05	0.60	FALSE
8	GTEx	Adrenal Gland	PPIEL	0.29	0.01	lasso	3	0.00	2.9e-01	-3.89	5.4	5.8e-08	0.21	0.04	0.11	TRUE
9	GTEx	Artery Coronary	RP11-69E11.4	0.63	-0.01	lasso	9	0.10	2.2e-04	6.75	5.3	1.1e-07	0.58	0.12	0.22	FALSE
10	GTEx	Artery Tibial	PABPC4	0.10	0.10	lasso	4	0.10	3.4e-08	6.79	-6.5	6.8e-11	-0.78	0.60	0.40	TRUE
11	GTEx	Artery Tibial	RP11-69E11.4	0.15	0.16	lasso	6	0.16	8.3e-13	6.00	5.4	5.4e-08	0.60	1.00	0.00	FALSE
12	GTEx	Brain Frontal Cortex BA9	RP11-69E11.4	0.23	0.10	lasso	6	0.11	7.2e-04	6.75	6.6	3.6e-11	0.52	0.13	0.19	FALSE
13	GTEx	Breast Mammary Tissue	PABPC4	0.13	0.02	enet	14	0.04	3.4e-03	6.88	-6.6	3.7e-11	-0.77	0.07	0.84	FALSE
14	GTEx	Breast Mammary Tissue	RP11-69E11.4	0.15	0.05	enet	32	0.05	8.8e-04	3.49	5.7	1.6e-08	0.63	0.30	0.65	FALSE
15	GTEx	Breast Mammary Tissue (Female)	PABPC4	0.10	0.00	enet	9	0.01	1.5e-01	7.80	-8.2	2.1e-16	-0.88	0.04	0.37	FALSE
16	GTEx	Cells Transformed fibroblasts	PABPC4	0.07	0.09	lasso	1	0.06	2.7e-05	6.79	-6.8	1.1e-11	-0.74	0.07	0.91	FALSE
17	GTEx	Colon Transverse	RP11-69E11.4	0.23	0.12	lasso	4	0.15	1.8e-07	6.88	5.8	7.8e-09	0.74	0.13	0.87	FALSE
18	GTEx	Esophagus Mucosa	PABPC4	0.06	0.06	lasso	3	0.08	7.3e-06	6.88	-6.8	1.4e-11	-0.79	0.17	0.80	FALSE
19	GTEx	Esophagus Mucosa	RP11-69E11.4	0.18	0.06	lasso	9	0.07	2.2e-05	6.00	6.3	3.6e-10	0.71	0.57	0.41	FALSE
20	GTEx	Esophagus Mucosa	BMP8A	0.08	0.02	lasso	2	0.01	1.4e-01	-1.61	5.8	6.7e-09	0.78	0.04	0.94	FALSE
21	GTEx	Esophagus Mucosa	PPIEL	0.11	0.02	lasso	3	0.02	9.4e-03	6.31	5.6	2.4e-08	0.81	0.07	0.78	FALSE
22	GTEx	Heart Left Ventricle	RP11-69E11.4	0.10	0.10	lasso	4	0.08	3.8e-05	6.00	5.3	1.1e-07	0.55	0.45	0.31	FALSE
23	GTEx	Lung	PABPC4	0.05	0.03	lasso	3	0.02	1.3e-02	6.79	-6.2	4.4e-10	-0.70	0.17	0.60	FALSE
24	GTEx	Lung	RP11-69E11.4	0.26	0.09	lasso	9	0.20	3.8e-15	-1.61	5.3	1.2e-07	0.54	0.89	0.11	TRUE
25	GTEx	Nerve Tibial	PABPC4	0.17	0.08	enet	12	0.05	2.7e-04	6.79	-6.3	3.7e-10	-0.76	0.16	0.84	FALSE
26	GTEx	Nerve Tibial	RP11-69E11.4	0.18	0.08	lasso	5	0.18	1.3e-12	6.02	5.6	1.9e-08	0.73	0.37	0.63	FALSE
27	GTEx	Nerve Tibial	RP11-69E11.8	0.05	0.00	lasso	3	0.01	6.9e-02	6.79	-7.1	1.6e-12	-0.80	0.04	0.84	FALSE
28	GTEx	Ovary	RP11-69E11.4	0.25	0.05	enet	11	0.03	6.7e-02	6.87	7.3	4.0e-13	0.67	0.05	0.36	TRUE
29	GTEx	Skin Not Sun Exposed Suprapubic	PABPC4	0.12	0.10	lasso	3	0.05	1.0e-03	6.88	-6.9	4.3e-12	-0.77	0.18	0.62	FALSE
30	GTEx	Skin Sun Exposed Lower leg	PABPC4	0.11	0.09	lasso	7	0.08	2.7e-07	6.88	-6.3	2.4e-10	-0.78	0.12	0.88	FALSE
31	GTEx	Skin Sun Exposed Lower leg	RP11-69E11.4	0.13	0.12	lasso	6	0.15	1.3e-12	6.24	6.6	3.1e-11	0.78	0.95	0.05	FALSE
32	GTEx	Spleen	RP11-69E11.4	0.25	0.12	lasso	4	0.15	9.3e-05	6.00	6.8	1.5e-11	0.75	0.15	0.67	FALSE
33	GTEx	Spleen	BMP8A	0.16	0.08	lasso	3	0.05	1.6e-02	6.24	5.9	3.1e-09	0.80	0.07	0.33	FALSE
34	GTEx	Stomach	RP11-69E11.4	0.31	0.20	lasso	4	0.20	4.0e-10	6.00	6.3	2.4e-10	0.60	0.73	0.27	FALSE
35	GTEx	Thyroid	PABPC4	0.08	0.03	lasso	6	0.05	1.3e-04	7.85	-5.7	1.4e-08	-0.85	0.02	0.97	FALSE
36	GTEx	Thyroid	RP11-69E11.4	0.17	0.04	lasso	9	0.06	4.4e-05	6.00	5.7	1.1e-08	0.63	0.13	0.75	FALSE
37	METSIM	Adipose	PABPC4	0.05	0.02	lasso	6	0.03	6.0e-05	6.88	-6.1	1.1e-09	-0.76	0.10	0.89	FALSE
38	NTR	Blood	KIAA0754	0.03	0.00	bslmm	366	0.01	1.6e-03	-0.43	6.5	6.4e-11	0.67	0.04	0.90	FALSE
39	NTR	Blood	PABPC4	0.01	0.00	blup	383	0.00	2.8e-02	6.79	-6.6	4.4e-11	-0.75	0.03	0.68	FALSE
40	The Cancer Genome Atlas	Breast Invasive Carcinoma	BMP8A	0.05	0.01	lasso	6	0.02	5.5e-05	6.88	6.2	7.3e-10	0.61	0.43	0.26	FALSE
41	The Cancer Genome Atlas	Breast Invasive Carcinoma	PABPC4	0.03	0.03	lasso	2	0.04	1.3e-08	6.79	-7.1	1.4e-12	-0.68	0.00	1.00	FALSE
42	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	PPIEL	0.06	0.08	lasso	1	0.05	1.4e-03	6.02	6.0	1.7e-09	0.47	0.02	0.84	FALSE
43	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BMP8A	0.04	0.03	blup	48	0.04	3.5e-05	6.00	8.1	4.5e-16	0.75	0.02	0.97	FALSE
44	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PABPC4	0.03	0.01	enet	4	0.02	4.3e-03	6.79	-6.3	3.8e-10	-0.75	0.00	0.98	FALSE
45	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PABPC4	0.04	0.05	blup	31	0.04	1.2e-05	6.75	-6.9	5.8e-12	-0.62	0.01	0.99	FALSE
46	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPIEL	0.03	0.03	lasso	4	0.02	5.1e-03	6.75	5.3	9.2e-08	0.54	0.01	0.96	FALSE
47	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PABPC4	0.05	0.05	enet	4	0.05	5.5e-04	6.88	-5.2	2.3e-07	-0.72	0.00	0.96	FALSE
48	The Cancer Genome Atlas	Brain Lower Grade Glioma	BMP8A	0.05	0.01	blup	48	0.04	6.8e-05	7.63	8.2	1.6e-16	0.76	0.00	0.98	FALSE
49	The Cancer Genome Atlas	Lung Adenocarcinoma	PABPC4	0.04	0.03	enet	8	0.04	4.5e-05	6.88	-7.3	2.7e-13	-0.69	0.00	1.00	TRUE
50	The Cancer Genome Atlas	Prostate Adenocarcinoma	PABPC4	0.14	0.03	enet	8	0.08	2.3e-08	6.79	-5.1	3.1e-07	-0.62	0.00	1.00	FALSE
51	The Cancer Genome Atlas	Prostate Adenocarcinoma	PPIEL	0.04	0.02	lasso	4	0.02	1.7e-03	6.00	5.8	6.3e-09	0.61	0.03	0.64	FALSE
52	The Cancer Genome Atlas	Thyroid Carcinoma	PABPC4	0.09	0.07	enet	5	0.08	4.1e-08	6.79	-7.9	2.1e-15	-0.65	0.00	1.00	FALSE