[Hub]/) : Traits : BMI :

chr1:31,402,148-34,592,020

Best TWAS P=8.02e-14 · Best GWAS P=6.68e-12 conditioned to 0.681

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex S100PBP 0.05 0.04 enet 10 0.02 1.2e-03 -6.9 5.8 5.4e-09 -0.97 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex TMEM54 0.05 0.00 blup 281 0.02 4.5e-03 1.6 -7.4 9.9e-14 0.41 0.10 0.32 FALSE
3 CommonMind Brain Pre-frontal Cortex ZNF362 0.05 0.06 lasso 1 0.06 2.2e-07 -5.8 -5.8 5.5e-09 0.09 0.78 0.21 FALSE
4 GTEx Cells EBV-transformed lymphocytes PHC2 0.58 0.34 lasso 7 0.28 7.3e-10 -5.9 6.0 1.9e-09 -0.06 0.36 0.64 TRUE
5 GTEx Muscle Skeletal FNDC5 0.15 0.16 enet 5 0.16 1.9e-15 -6.2 -6.3 3.2e-10 0.96 0.10 0.90 FALSE
6 METSIM Adipose PEF1 0.03 0.02 enet 17 0.02 7.9e-04 -5.0 5.3 1.5e-07 0.09 0.35 0.20 TRUE
7 ROSMAP Brain Pre-frontal Cortex PHC2 0.11 0.07 lasso 3 0.05 2.2e-07 -5.9 -5.6 1.8e-08 0.05 0.37 0.63 FALSE
8 ROSMAP Brain Pre-frontal Cortex PEF1 0.04 0.04 lasso 3 0.02 4.2e-04 -4.9 5.2 2.0e-07 0.11 0.54 0.34 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma FNDC5 0.02 0.01 blup 33 0.01 9.2e-03 -5.4 -5.7 1.2e-08 0.79 0.02 0.44 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma S100PBP 0.03 0.02 blup 46 0.02 6.6e-06 -6.8 5.9 3.6e-09 -0.91 0.01 0.99 FALSE
11 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma S100PBP 0.06 0.03 blup 48 0.06 6.8e-04 -6.4 7.5 8.0e-14 -0.91 0.01 0.82 TRUE
12 The Cancer Genome Atlas Glioblastoma Multiforme S100PBP 0.21 0.15 lasso 5 0.15 2.9e-05 -6.2 6.2 4.4e-10 -0.96 0.01 0.91 FALSE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma S100PBP 0.04 0.04 lasso 4 0.04 2.3e-05 -6.8 6.8 1.1e-11 -1.00 0.00 0.99 FALSE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FNDC5 0.03 0.04 enet 6 0.03 2.9e-04 -6.4 -5.6 1.9e-08 0.80 0.02 0.95 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma HPCA 0.05 0.09 lasso 7 0.08 3.6e-09 -5.3 5.8 6.2e-09 -0.78 0.12 0.88 FALSE
16 The Cancer Genome Atlas Brain Lower Grade Glioma S100PBP 0.06 0.06 blup 47 0.05 5.2e-06 -6.8 7.0 1.9e-12 -0.92 0.00 1.00 FALSE