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chr17:7,044,746-8,484,683
Best TWAS P=3.74e-09 · Best GWAS P=3.67e-09 conditioned to 1
7M
7.2M
7.4M
7.6M
7.8M
8M
8.2M
8.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Colon Adenocarcinoma
CYB5D1
0.14
0.12
lasso
1
0.10
1.7e-06
5.9
-5.9
3.7e-09
-1.00
0.00
1.00
TRUE
4
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
TNFSF12
0.04
0.01
enet
9
0.01
4.3e-02
4.3
-5.1
3.1e-07
-0.08
0.01
0.49
TRUE
1
GTEx
Colon Transverse
LSMD1
0.28
0.12
lasso
5
0.19
3.3e-09
5.9
5.8
5.2e-09
0.89
0.00
0.99
FALSE
2
ROSMAP
Brain Pre-frontal Cortex
KDM6B
0.07
0.05
lasso
4
0.04
2.7e-06
5.9
-5.2
1.6e-07
-0.95
0.00
1.00
FALSE