[Hub]/) : Traits : Height :

chr1:66,585,659-69,212,053

Best TWAS P=1.07e-25 · Best GWAS P=3.33e-25 conditioned to 0.799

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex WDR78 0.13 0.14 lasso 3 0.14 1.7e-16 -7.95 8.0 1.9e-15 -0.73 0.83 0.17 FALSE
2 GTEx Artery Aorta MIER1 0.18 0.07 lasso 7 0.10 3.7e-06 -2.40 -7.2 4.4e-13 0.76 0.04 0.95 FALSE
3 GTEx Artery Tibial WDR78 0.14 0.09 lasso 8 0.09 2.1e-07 -10.13 10.5 1.1e-25 -0.91 0.02 0.98 TRUE
4 GTEx Artery Tibial MIER1 0.12 0.08 lasso 4 0.07 6.3e-06 -10.17 -10.2 2.7e-24 0.85 0.03 0.97 FALSE
5 GTEx Breast Mammary Tissue MIER1 0.12 0.07 lasso 2 0.05 8.5e-04 -10.37 -10.4 2.2e-25 1.00 0.01 0.97 FALSE
6 GTEx Breast Mammary Tissue (Female) MIER1 0.21 -0.01 lasso 6 0.00 4.3e-01 -7.95 -8.7 2.8e-18 0.80 0.04 0.56 FALSE
7 GTEx Cells Transformed fibroblasts MIER1 0.19 0.09 lasso 7 0.10 3.1e-08 -7.95 -9.0 2.2e-19 0.87 0.04 0.96 FALSE
8 GTEx Esophagus Muscularis MIER1 0.14 0.05 enet 9 0.04 2.5e-03 -10.13 -10.3 5.0e-25 0.80 0.03 0.92 FALSE
9 GTEx Nerve Tibial WDR78 0.13 0.07 lasso 5 0.06 7.5e-05 -10.12 9.3 1.2e-20 -0.82 0.03 0.97 FALSE
10 GTEx Nerve Tibial DIRAS3 0.18 0.01 lasso 6 0.05 1.3e-04 -3.92 5.2 2.0e-07 -0.01 0.05 0.90 TRUE
11 GTEx Testis WDR78 0.45 0.42 lasso 6 0.40 5.0e-19 -10.13 -10.2 1.8e-24 0.85 0.03 0.97 FALSE
12 GTEx Thyroid WDR78 0.12 0.11 lasso 3 0.09 2.4e-07 -9.93 10.4 4.0e-25 -0.91 0.02 0.98 FALSE
13 METSIM Adipose MIER1 0.05 0.05 enet 19 0.04 2.8e-07 -7.95 -9.7 3.5e-22 0.83 0.03 0.97 FALSE
14 NTR Blood MIER1 0.03 0.01 bslmm 573 0.01 2.7e-05 -10.09 -6.8 1.3e-11 0.57 0.04 0.96 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma WDR78 0.02 0.01 blup 86 0.02 2.4e-04 -10.11 8.1 8.5e-16 -0.70 0.01 0.94 FALSE
16 The Cancer Genome Atlas Brain Lower Grade Glioma C1orf141 0.12 0.06 blup 70 0.08 2.9e-09 1.19 5.4 5.9e-08 -0.12 1.00 0.00 TRUE
17 The Cancer Genome Atlas Testicular Germ Cell Tumors IL23R 0.25 0.07 lasso 8 0.05 1.0e-02 -5.12 -5.2 2.6e-07 0.48 0.02 0.67 FALSE
18 The Cancer Genome Atlas Thyroid Carcinoma MIER1 0.19 0.05 blup 58 0.06 1.7e-06 -10.37 -7.5 5.7e-14 0.78 0.00 1.00 FALSE
19 The Cancer Genome Atlas Thyroid Carcinoma SLC35D1 0.13 0.10 enet 16 0.20 9.2e-19 -6.98 -6.2 5.9e-10 0.64 1.00 0.00 FALSE
20 The Cancer Genome Atlas Thyroid Carcinoma WDR78 0.10 0.00 blup 86 0.07 1.6e-07 -0.67 6.0 1.4e-09 -0.54 0.04 0.91 FALSE