[Hub]/) : Traits : Height :

chr4:119,408,351-121,242,474

Best TWAS P=7.4e-14 · Best GWAS P=2.08e-18 conditioned to 2.52e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex USP53 0.16 0.13 lasso 11 0.20 3.5e-23 5.2 6.0 1.7e-09 -0.18 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous RP11-33B1.1 0.23 0.10 lasso 12 0.18 4.7e-15 5.0 6.0 1.5e-09 -0.24 0.99 0.01 FALSE
3 GTEx Adrenal Gland RP11-33B1.1 0.13 0.07 enet 25 0.09 5.5e-04 -3.9 5.2 2.1e-07 -0.23 0.71 0.02 FALSE
4 GTEx Artery Coronary RP11-33B1.4 0.10 0.02 lasso 2 0.01 1.5e-01 -5.6 -5.7 9.9e-09 0.40 0.22 0.10 FALSE
5 GTEx Cells EBV-transformed lymphocytes USP53 0.13 0.01 lasso 5 0.02 8.8e-02 -5.6 5.8 5.4e-09 -0.37 0.12 0.09 FALSE
6 GTEx Liver RP11-33B1.4 0.18 0.14 lasso 6 0.12 3.2e-04 -5.9 5.3 1.3e-07 -0.31 0.72 0.04 FALSE
7 GTEx Nerve Tibial RP11-33B1.4 0.21 0.10 lasso 7 0.12 6.2e-09 -5.8 7.1 1.2e-12 -0.05 0.76 0.01 TRUE
8 GTEx Ovary RP11-33B1.1 0.26 0.07 enet 33 0.16 1.2e-04 5.2 7.5 7.4e-14 -0.41 0.21 0.29 TRUE
9 GTEx Pancreas RP11-33B1.1 0.13 0.18 lasso 5 0.18 4.7e-08 -3.9 5.2 2.4e-07 -0.28 0.99 0.00 FALSE
10 GTEx Pancreas RP11-33B1.4 0.20 0.05 lasso 16 0.05 3.8e-03 -5.5 6.2 5.0e-10 -0.45 0.68 0.04 FALSE
11 GTEx Skin Sun Exposed Lower leg RP11-33B1.4 0.12 0.01 lasso 6 0.01 4.7e-02 -5.8 7.0 2.3e-12 -0.05 0.20 0.03 FALSE
12 GTEx Small Intestine Terminal Ileum RP11-33B1.1 0.15 0.10 lasso 19 0.09 5.4e-03 -3.9 5.2 2.6e-07 -0.26 0.22 0.06 FALSE
13 GTEx Spleen RP11-33B1.1 0.22 0.03 enet 17 0.02 7.7e-02 5.2 5.2 1.5e-07 -0.20 0.17 0.05 FALSE
14 GTEx Testis RP11-33B1.4 0.23 0.31 enet 16 0.37 1.5e-17 -3.9 5.8 5.6e-09 -0.35 1.00 0.00 FALSE
15 GTEx Thyroid PDE5A 0.09 0.04 lasso 3 0.04 6.9e-04 6.2 5.9 4.1e-09 0.00 0.27 0.04 FALSE
16 GTEx Thyroid RP11-33B1.4 0.07 0.07 lasso 3 0.05 1.8e-04 -5.9 6.2 4.4e-10 -0.28 0.72 0.10 FALSE
17 The Cancer Genome Atlas Colon Adenocarcinoma FABP2 0.24 0.20 lasso 9 0.25 1.8e-14 5.3 -6.0 1.4e-09 0.22 0.06 0.94 FALSE
18 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SEC24D 0.06 0.00 blup 86 0.02 3.1e-03 -3.9 -5.4 6.2e-08 0.05 0.01 0.67 TRUE
19 The Cancer Genome Atlas Brain Lower Grade Glioma USP53 0.25 0.05 lasso 5 0.08 6.5e-09 -4.6 6.1 1.1e-09 0.01 0.63 0.30 FALSE
20 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SEC24D 0.06 0.02 enet 9 0.03 8.9e-05 -4.3 -5.1 3.0e-07 0.05 0.02 0.84 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma USP53 0.11 0.03 blup 88 0.07 5.8e-07 5.1 6.2 4.4e-10 -0.13 0.51 0.42 FALSE