[Hub]/) : Traits : Height :

chr1:91,271,668-94,716,440

Best TWAS P=1.5e-42 · Best GWAS P=7.43e-39 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex BTBD8 0.06 0.00 bslmm 441 0.02 1.3e-03 6.6 -8.0 1.4e-15 0.02 0.05 0.03 TRUE
2 CommonMind Brain Pre-frontal Cortex DR1 0.21 0.20 blup 305 0.23 1.8e-27 6.1 5.2 2.2e-07 -0.19 1.00 0.00 FALSE
3 CommonMind Brain Pre-frontal Cortex EVI5 0.03 0.01 blup 335 0.02 1.3e-03 -13.0 -13.6 3.0e-42 0.92 0.02 0.96 FALSE
4 CommonMind Brain Pre-frontal Cortex FAM69A 0.10 0.13 lasso 4 0.14 1.2e-16 -11.8 -13.2 5.0e-40 0.76 0.96 0.04 FALSE
5 CommonMind Brain Pre-frontal Cortex RPAP2 0.20 0.06 enet 29 0.16 8.6e-19 -11.5 -11.9 7.1e-33 0.69 0.15 0.85 FALSE
6 GTEx Adipose Subcutaneous EVI5 0.09 0.07 lasso 3 0.09 1.2e-07 -11.9 -12.3 1.3e-34 0.66 0.49 0.51 FALSE
7 GTEx Adipose Subcutaneous CCDC18 0.06 0.00 lasso 6 0.01 2.1e-02 2.4 -8.8 9.9e-19 0.48 0.03 0.87 TRUE
8 GTEx Adipose Subcutaneous RPAP2 0.12 0.02 lasso 8 0.04 3.1e-04 4.1 -8.9 4.9e-19 0.46 0.56 0.06 TRUE
9 GTEx Adipose Subcutaneous FAM69A 0.08 0.06 lasso 7 0.04 3.8e-04 -8.1 9.7 4.6e-22 -0.80 0.02 0.97 FALSE
10 GTEx Adipose Visceral Omentum EVI5 0.13 0.08 lasso 2 0.07 2.3e-04 -10.9 -10.8 2.4e-27 0.64 0.44 0.18 FALSE
11 GTEx Adipose Visceral Omentum DR1 0.10 0.05 lasso 5 0.06 5.0e-04 5.0 5.2 1.9e-07 -0.19 0.83 0.01 FALSE
12 GTEx Adrenal Gland SNORD21 0.20 0.09 enet 28 0.11 7.1e-05 -13.0 -8.4 5.3e-17 0.60 0.02 0.82 FALSE
13 GTEx Artery Aorta DR1 0.15 0.10 lasso 5 0.14 3.1e-08 2.5 5.1 2.9e-07 -0.19 1.00 0.00 FALSE
14 GTEx Artery Aorta FNBP1L 0.13 0.03 lasso 1 0.00 1.9e-01 8.4 8.4 5.0e-17 -0.10 0.16 0.08 TRUE
15 GTEx Artery Aorta FAM69A 0.34 0.22 lasso 7 0.27 3.9e-15 -8.2 7.7 1.7e-14 -0.69 0.97 0.03 FALSE
16 GTEx Artery Coronary EVI5 0.09 0.10 lasso 2 0.07 3.1e-03 -11.9 -11.9 1.3e-32 0.64 0.09 0.60 FALSE
17 GTEx Artery Coronary FAM69A 0.25 0.25 lasso 2 0.26 3.4e-09 -8.1 8.7 4.7e-18 -0.68 0.32 0.61 FALSE
18 GTEx Artery Tibial EVI5 0.08 0.08 lasso 10 0.12 9.5e-10 -12.5 -12.8 1.5e-37 0.88 0.12 0.88 FALSE
19 GTEx Artery Tibial FAM69A 0.35 0.34 enet 36 0.36 3.6e-29 -8.1 5.7 1.3e-08 -0.51 1.00 0.00 FALSE
20 GTEx Brain Caudate basal ganglia EVI5 0.10 0.00 enet 19 0.01 1.7e-01 -13.0 -11.6 3.3e-31 0.82 0.04 0.69 FALSE
21 GTEx Brain Cerebellar Hemisphere CDC7 0.28 0.18 lasso 3 0.14 2.6e-04 -5.5 5.3 1.4e-07 -0.13 0.35 0.07 FALSE
22 GTEx Brain Cerebellar Hemisphere TMED5 0.37 0.06 enet 21 0.11 1.1e-03 8.3 -7.5 7.0e-14 0.27 0.23 0.35 FALSE
23 GTEx Brain Cortex EVI5 0.25 0.33 lasso 13 0.30 4.1e-09 -13.0 -13.2 9.9e-40 0.99 0.01 0.98 FALSE
24 GTEx Brain Frontal Cortex BA9 CCDC18 0.12 0.02 enet 26 0.04 3.7e-02 3.5 -5.6 2.5e-08 0.37 0.04 0.42 FALSE
25 GTEx Brain Hypothalamus EVI5 0.16 0.12 lasso 13 0.05 2.1e-02 -12.9 -13.1 4.0e-39 1.00 0.02 0.87 FALSE
26 GTEx Breast Mammary Tissue EVI5 0.07 0.06 lasso 4 0.07 2.3e-04 -13.0 -13.0 7.7e-39 0.99 0.02 0.98 FALSE
27 GTEx Breast Mammary Tissue (Male) EVI5 0.17 0.03 lasso 10 0.08 5.9e-03 -12.5 -10.9 9.7e-28 0.82 0.04 0.57 FALSE
28 GTEx Cells Transformed fibroblasts EVI5 0.18 0.11 enet 28 0.20 5.9e-15 -11.4 -13.3 1.5e-40 0.83 0.10 0.90 FALSE
29 GTEx Cells Transformed fibroblasts CDC7 0.21 0.14 enet 26 0.10 2.7e-08 -5.2 5.2 1.8e-07 -0.14 1.00 0.00 FALSE
30 GTEx Cells Transformed fibroblasts FAM69A 0.24 0.19 lasso 7 0.17 4.9e-13 -8.1 8.0 1.1e-15 -0.62 1.00 0.00 FALSE
31 GTEx Colon Sigmoid EVI5 0.13 0.16 lasso 3 0.12 7.0e-05 -13.0 -13.0 8.8e-39 1.00 0.01 0.98 FALSE
32 GTEx Colon Transverse EVI5 0.21 0.08 lasso 9 0.14 4.2e-07 -8.1 -12.3 1.1e-34 0.77 0.03 0.97 TRUE
33 GTEx Esophagus Gastroesophageal Junction EVI5 0.22 0.10 lasso 7 0.06 2.3e-03 -10.9 -12.9 2.9e-38 0.84 0.04 0.96 FALSE
34 GTEx Esophagus Mucosa EVI5 0.12 0.19 lasso 4 0.19 6.0e-13 -10.9 -12.8 3.0e-37 0.83 0.04 0.96 FALSE
35 GTEx Esophagus Mucosa CDC7 0.31 0.36 lasso 3 0.36 5.4e-25 -5.5 5.5 4.2e-08 -0.14 1.00 0.00 FALSE
36 GTEx Esophagus Muscularis EVI5 0.16 0.23 lasso 5 0.23 4.9e-14 -10.9 -11.7 7.1e-32 0.70 0.49 0.51 TRUE
37 GTEx Heart Atrial Appendage EVI5 0.09 0.06 lasso 7 0.05 4.2e-03 -13.0 -13.0 9.3e-39 1.00 0.02 0.95 FALSE
38 GTEx Heart Left Ventricle EVI5 0.07 0.11 lasso 5 0.08 7.7e-05 -13.0 -13.5 2.3e-41 0.99 0.01 0.98 FALSE
39 GTEx Lung EVI5 0.11 0.08 lasso 11 0.13 7.0e-10 -11.4 -13.1 4.8e-39 0.86 0.02 0.98 FALSE
40 GTEx Lung RPAP2 0.08 0.04 enet 27 0.06 1.0e-05 7.1 -8.9 8.1e-19 0.61 0.36 0.47 FALSE
41 GTEx Nerve Tibial EVI5 0.17 0.13 enet 25 0.18 4.5e-13 -10.7 -12.3 1.5e-34 0.84 0.09 0.91 TRUE
42 GTEx Nerve Tibial CCDC18 0.06 0.04 lasso 11 0.04 7.2e-04 3.7 -6.2 6.9e-10 0.30 0.45 0.03 FALSE
43 GTEx Nerve Tibial FAM69A 0.17 0.03 enet 19 0.05 1.4e-04 -8.2 9.8 1.6e-22 -0.64 0.50 0.43 FALSE
44 GTEx Pancreas FAM69A 0.10 0.08 enet 12 0.04 1.1e-02 -11.9 -7.7 1.2e-14 0.51 0.21 0.18 FALSE
45 GTEx Skin Not Sun Exposed Suprapubic EVI5 0.07 0.05 lasso 6 0.08 2.2e-05 -10.7 -11.3 2.1e-29 0.72 0.06 0.93 FALSE
46 GTEx Skin Not Sun Exposed Suprapubic CDC7 0.14 0.16 lasso 3 0.16 7.9e-09 -5.5 5.4 8.1e-08 -0.14 0.99 0.00 FALSE
47 GTEx Spleen EVI5 0.21 0.15 enet 22 0.25 3.3e-07 -12.7 -11.4 2.6e-30 0.79 0.04 0.94 FALSE
48 GTEx Spleen CCDC18 0.29 0.07 lasso 10 0.15 9.2e-05 6.1 -6.1 1.1e-09 0.24 0.34 0.10 FALSE
49 GTEx Stomach EVI5 0.12 0.13 lasso 6 0.14 4.7e-07 -10.9 -9.3 2.1e-20 0.52 0.61 0.38 FALSE
50 GTEx Testis TMED5 0.27 0.31 lasso 5 0.30 6.9e-14 6.1 -5.9 3.3e-09 0.22 1.00 0.00 FALSE
51 GTEx Thyroid DR1 0.09 0.01 enet 14 0.04 5.3e-04 8.3 5.3 1.3e-07 -0.08 0.13 0.18 FALSE
52 GTEx Thyroid RPAP2 0.04 0.03 enet 15 0.03 4.2e-03 7.5 -10.4 2.0e-25 0.47 0.22 0.20 FALSE
53 GTEx Thyroid FAM69A 0.43 0.18 enet 41 0.20 5.5e-15 8.4 11.6 4.5e-31 -0.44 1.00 0.00 FALSE
54 GTEx Uterus EVI5 0.23 0.12 enet 27 0.16 4.3e-04 -13.0 -12.9 6.8e-38 0.90 0.04 0.88 FALSE
55 GTEx Whole Blood EVI5 0.03 0.01 lasso 2 0.01 6.8e-02 -13.0 -13.7 1.5e-42 0.96 0.02 0.97 TRUE
56 METSIM Adipose EVI5 0.14 0.10 enet 35 0.11 1.0e-15 -10.7 -9.1 6.1e-20 0.61 1.00 0.00 FALSE
57 METSIM Adipose FAM69A 0.03 0.03 bslmm 293 0.02 1.8e-03 -12.2 9.6 5.6e-22 -0.61 0.60 0.10 FALSE
58 NTR Blood FNBP1L 0.03 0.03 lasso 4 0.03 1.1e-10 4.5 6.2 5.3e-10 -0.09 1.00 0.00 FALSE
59 NTR Blood RPAP2 0.01 0.01 enet 16 0.00 9.5e-03 9.2 -6.2 5.4e-10 0.18 0.46 0.01 FALSE
60 NTR Blood TMED5 0.01 0.01 blup 277 0.01 5.2e-04 3.7 -7.0 3.6e-12 0.31 0.60 0.01 FALSE
61 ROSMAP Brain Pre-frontal Cortex DR1 0.09 0.12 enet 20 0.16 1.2e-20 2.4 5.3 1.3e-07 -0.21 1.00 0.00 FALSE
62 ROSMAP Brain Pre-frontal Cortex FAM69A 0.10 0.13 lasso 4 0.15 2.4e-19 -8.9 -12.0 2.3e-33 0.70 1.00 0.00 FALSE
63 YFS Blood DR1 0.11 0.17 lasso 17 0.19 2.0e-58 8.3 6.3 2.4e-10 -0.24 1.00 0.00 FALSE
64 YFS Blood FAM69A 0.28 0.09 enet 29 0.13 4.9e-40 8.4 10.6 2.8e-26 -0.42 1.00 0.00 FALSE
65 The Cancer Genome Atlas Breast Invasive Carcinoma CDC7 0.07 0.12 enet 13 0.14 1.2e-27 -5.2 5.6 2.0e-08 -0.11 0.01 0.99 TRUE
66 The Cancer Genome Atlas Breast Invasive Carcinoma DR1 0.04 0.04 lasso 3 0.04 1.5e-08 8.3 7.3 2.2e-13 -0.24 0.01 0.99 FALSE
67 The Cancer Genome Atlas Breast Invasive Carcinoma EVI5 0.03 0.03 lasso 4 0.04 3.6e-09 -10.9 -13.2 7.2e-40 0.89 0.04 0.96 FALSE
68 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma CDC7 0.15 0.14 lasso 3 0.11 6.0e-06 -5.5 5.6 2.3e-08 -0.13 0.00 1.00 FALSE
69 The Cancer Genome Atlas Colon Adenocarcinoma CDC7 0.17 0.18 enet 14 0.17 7.8e-10 -5.5 5.4 8.4e-08 -0.07 0.00 1.00 FALSE
70 The Cancer Genome Atlas Colon Adenocarcinoma DR1 0.36 0.06 enet 9 0.06 2.2e-04 3.7 5.1 2.8e-07 -0.18 0.05 0.68 FALSE
71 The Cancer Genome Atlas Colon Adenocarcinoma EVI5 0.07 0.04 blup 93 0.03 4.7e-03 -12.2 -13.1 4.4e-39 0.79 0.10 0.51 FALSE
72 The Cancer Genome Atlas Colon Adenocarcinoma FAM69A 0.05 0.01 enet 7 0.02 3.6e-02 -7.8 -9.3 2.0e-20 0.47 0.03 0.57 FALSE
73 The Cancer Genome Atlas Glioblastoma Multiforme EVI5 0.14 0.04 blup 93 0.06 8.9e-03 -9.2 -12.5 5.6e-36 0.88 0.03 0.75 TRUE
74 The Cancer Genome Atlas Glioblastoma Multiforme TMED5 0.08 0.05 blup 39 0.03 4.7e-02 6.1 -6.0 1.7e-09 0.23 0.01 0.69 FALSE
75 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CDC7 0.34 0.32 enet 12 0.32 3.8e-36 -5.5 5.5 4.2e-08 -0.15 0.00 1.00 FALSE
76 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma EVI5 0.08 0.04 blup 96 0.06 8.6e-08 -10.7 -13.4 6.0e-41 0.88 0.03 0.97 FALSE
77 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FAM69A 0.05 0.03 blup 62 0.05 4.4e-06 -11.8 -12.1 1.7e-33 0.53 0.02 0.98 FALSE
78 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DR1 0.05 0.05 blup 29 0.06 4.1e-07 6.1 5.8 5.4e-09 -0.22 0.08 0.92 FALSE
79 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma EVI5 0.07 0.05 blup 96 0.06 2.5e-07 -10.9 -12.6 3.9e-36 0.80 0.15 0.85 FALSE
80 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EVI5 0.04 0.02 blup 96 0.04 1.4e-03 -9.1 -12.5 4.9e-36 0.85 0.03 0.68 FALSE
81 The Cancer Genome Atlas Brain Lower Grade Glioma DR1 0.03 0.03 blup 29 0.03 1.1e-04 8.4 7.2 5.2e-13 -0.23 0.01 0.97 FALSE
82 The Cancer Genome Atlas Brain Lower Grade Glioma EVI5 0.18 0.16 lasso 7 0.15 2.0e-16 -13.0 -13.5 1.6e-41 0.98 0.01 0.99 FALSE
83 The Cancer Genome Atlas Brain Lower Grade Glioma TMED5 0.08 0.06 enet 12 0.07 3.5e-08 6.1 -5.9 4.1e-09 0.23 0.74 0.26 FALSE
84 The Cancer Genome Atlas Liver Hepatocellular Carcinoma CDC7 0.07 0.07 enet 3 0.06 1.0e-03 5.1 5.1 2.8e-07 -0.08 0.01 0.93 FALSE
85 The Cancer Genome Atlas Lung Adenocarcinoma CDC7 0.05 0.05 lasso 5 0.04 2.7e-05 -5.2 5.3 1.2e-07 -0.07 0.01 0.99 FALSE
86 The Cancer Genome Atlas Lung Adenocarcinoma EVI5 0.05 0.07 lasso 5 0.07 5.6e-09 -10.9 -12.5 1.1e-35 0.80 0.13 0.87 FALSE
87 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CDC7 0.07 0.13 enet 8 0.11 3.7e-12 -5.5 5.5 3.2e-08 -0.12 0.00 1.00 FALSE
88 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DR1 0.03 0.02 blup 29 0.02 3.2e-03 6.1 7.1 1.2e-12 -0.24 0.02 0.84 FALSE
89 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EVI5 0.04 0.04 blup 93 0.03 4.8e-04 -10.9 -13.1 3.1e-39 0.85 0.10 0.87 FALSE
90 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CDC7 0.08 0.04 blup 76 0.06 7.2e-05 3.5 5.2 2.1e-07 -0.11 0.01 0.99 FALSE
91 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma EVI5 0.05 0.02 blup 96 0.03 2.3e-03 -12.2 -13.2 8.5e-40 0.83 0.09 0.71 FALSE
92 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TMED5 0.05 0.05 enet 11 0.04 9.7e-04 5.1 -5.5 3.4e-08 0.17 0.04 0.71 FALSE
93 The Cancer Genome Atlas Pancreatic Adenocarcinoma DR1 0.09 0.09 lasso 2 0.07 4.7e-04 8.3 8.2 1.5e-16 -0.24 0.01 0.77 FALSE
94 The Cancer Genome Atlas Pancreatic Adenocarcinoma EVI5 0.10 0.06 blup 94 0.08 2.9e-04 -13.0 -13.6 3.0e-42 0.92 0.01 0.96 FALSE
95 The Cancer Genome Atlas Prostate Adenocarcinoma DR1 0.10 0.09 blup 29 0.08 3.9e-09 8.4 7.6 2.6e-14 -0.24 0.01 0.99 FALSE
96 The Cancer Genome Atlas Prostate Adenocarcinoma EVI5 0.06 0.10 blup 94 0.10 1.7e-10 -13.0 -13.7 1.7e-42 0.92 0.01 0.99 FALSE
97 The Cancer Genome Atlas Prostate Adenocarcinoma TMED5 0.07 0.02 enet 18 0.05 7.2e-06 2.6 -5.5 4.0e-08 0.15 0.03 0.82 FALSE
98 The Cancer Genome Atlas Soft Tissue Sarcoma CDC7 0.11 0.18 lasso 3 0.15 2.4e-09 -5.5 5.4 6.5e-08 -0.14 0.00 1.00 FALSE
99 The Cancer Genome Atlas Stomach Adenocarcinoma DR1 0.07 0.05 enet 9 0.07 6.2e-06 6.1 5.6 1.9e-08 -0.21 0.04 0.95 FALSE
100 The Cancer Genome Atlas Stomach Adenocarcinoma EVI5 0.14 0.07 lasso 3 0.08 3.4e-06 -10.9 -10.0 1.1e-23 0.61 0.71 0.24 FALSE
101 The Cancer Genome Atlas Stomach Adenocarcinoma TMED5 0.05 0.06 lasso 2 0.05 1.4e-04 5.6 -5.7 1.4e-08 0.24 0.05 0.85 FALSE
102 The Cancer Genome Atlas Testicular Germ Cell Tumors CDC7 0.17 0.14 lasso 8 0.14 9.9e-06 4.9 5.3 1.4e-07 -0.07 0.01 0.98 FALSE
103 The Cancer Genome Atlas Thyroid Carcinoma DR1 0.16 0.18 blup 29 0.19 4.1e-18 6.1 6.3 2.4e-10 -0.24 0.03 0.97 FALSE
104 The Cancer Genome Atlas Thyroid Carcinoma EVI5 0.05 0.01 blup 94 0.03 5.7e-04 -11.3 9.8 9.8e-23 -0.44 0.31 0.06 FALSE
105 The Cancer Genome Atlas Thyroid Carcinoma FAM69A 0.25 0.06 lasso 4 0.05 1.2e-05 8.4 8.1 7.3e-16 -0.26 0.80 0.01 FALSE