TWAS hub - FNBP1L

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1310	0.052	3.1e-03	0.031	NA	-0.005	NA	0.004	8.2e-03	NA	9.7e-01	NA	1.9e-01
2	GTEx	Cells Transformed fibroblasts	0.1620	0.057	5.6e-05	0.008	NA	0.025	NA	0.014	7.9e-02	NA	5.3e-03	NA	2.8e-02
3	NTR	Blood	0.0343	0.010	5.2e-07	0.028	0.022	0.030	0.03	0.032	1.9e-09	9.1e-08	4.2e-10	4.9e-10	1.1e-10
4	TCGA	Liver Hepatocellular Carcinoma	0.1260	0.086	8.6e-03	0.023	0.004	0.006	NA	0.008	2.9e-02	1.9e-01	1.6e-01	NA	1.3e-01
5	TCGA	Prostate Adenocarcinoma	0.0880	0.034	2.5e-08	0.089	0.073	0.069	NA	0.080	1.4e-09	4.5e-08	1.0e-07	NA	9.9e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
Hearing aid user	3.5	3.9	12.5	-1.4	-1.1	-1.9	-3.5	0.3
Medication: Omeprazole (e.g. Zanprol)	3.5	4.3	5.9	2.4	2.1	1.9	1.9	2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.4	4.0	7.1	2.7	2.2	2.2	1.5	0.9
Mouth/teeth dental problems: Dentures	3.2	5.4	10.9	2.8	2.7	3.3	1.1	0.4
Average weekly red wine intake	3.2	4.8	16.4	0.8	0.5	0.4	-4.1	-2.5
Alcohol intake frequency.	3.1	7.2	21.1	-1.4	-1.5	-1.0	3.1	4.6
Qualifications: NVQ or HND or HNC or equivalent	3.0	3.6	10.3	1.6	3.2	1.4	1.3	1.3
Knee pain experienced in last month	2.9	4.5	6.7	2.6	2.2	2.3	1.8	1.5
Medication: Omeprazole	2.8	3.3	5.0	2.0	2.2	1.8	1.6	1.4
Neck or shoulder pain in last month	2.6	3.6	7.7	2.8	1.8	2.6	0.7	0.2
Lupus	2.5	3.8	6.7	2.1	1.8	2.6	1.2	1.8
Family relationship satisfaction	2.5	3.1	4.5	-1.1	-2.0	-1.7	-1.8	2.1
Hand grip strength (left)	2.4	6.4	8.9	3.0	2.8	2.6	-1.8	-2.2
Forced vital capacity (FVC), Best measure	2.4	8.8	19.1	3.5	1.0	2.8	-1.9	-4.4
Medication: Aspirin	2.4	3.2	6.9	-1.9	-1.3	-1.8	-2.6	-0.9
Medication: Aspirin	2.4	3.1	5.9	-2.0	-1.2	-1.9	-2.4	-0.7
Comparative height size at age 10	2.3	12.7	25.9	5.1	2.1	4.6	3.3	-1.1
Breastfed as a baby	2.2	2.8	6.2	-0.7	-1.7	-1.2	-1.7	-2.5
Bipolar Disorder (2011)	2.1	2.0	3.5	-1.9	-1.7	-1.7	-0.4	0.9
Hand grip strength (right)	2.1	5.6	9.4	3.1	2.4	2.7	-1.0	-2.1
Alcohol usually taken with meals	2.1	3.3	7.0	-1.6	0.2	-1.6	-2.6	-2.1
Mouth/teeth dental problems	2.1	3.2	7.5	-2.7	-1.3	-2.6	-0.4	-0.4
Pulse rate	2.1	3.5	6.8	-1.8	0.4	-1.8	-2.6	-2.0
Migraine (self-reported)	2.1	2.6	9.9	-0.8	-0.3	-1.4	-0.5	3.1
Pain experienced in last month	2.1	3.5	6.2	-2.5	-1.2	-2.1	-1.6	-1.7
Medication: Co-codamol	2.0	2.3	6.8	1.2	0.3	1.3	1.2	2.6
Forced vital capacity (FVC)	2.0	7.6	14.6	3.8	1.4	2.9	-1.0	-3.5
Forced expiratory volume in 1-second (FEV1), Best measure	2.0	6.5	19.5	2.4	0.8	1.8	-1.7	-4.4
HDL Cholesterol	1.9	3.2	4.7	1.8	2.0	1.9	2.2	-0.7
Leg pain on walking	1.9	2.4	4.9	-2.2	-0.4	-2.0	0.6	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.9	4.1	10.4	-0.9	0.1	-0.6	-3.0	-3.2
Alcohol drinker status: Never	1.9	2.3	5.3	-2.3	-0.6	-1.6	-0.1	1.8
Irritable Bowel Disease (IBD)	1.8	4.4	8.7	-0.9	-2.7	-1.2	-3.0	-1.9
Supplements: Zinc	1.8	1.9	3.4	-1.7	-1.0	-1.8	-1.4	0.5
Financial difficulties in last 2 years	1.8	2.4	3.1	-1.5	-1.8	-1.8	-1.8	0.7
Peak expiratory flow (PEF)	1.8	4.2	7.8	2.8	1.2	2.7	0.5	-2.0
Pulse wave peak to peak time	1.8	2.1	3.4	1.5	0.5	1.1	1.8	-1.9
Handedness (chirality/laterality): Left-handed	1.8	2.1	3.3	1.5	1.0	1.4	1.8	1.5
Alcohol drinker status: Previous	1.8	2.0	6.4	-0.1	-1.9	-0.3	2.5	-0.2
Crohns Disease (2017)	1.7	3.8	7.0	-1.2	-1.9	-1.2	-2.3	-2.6
Average weekly spirits intake	1.7	2.1	4.2	1.8	1.5	2.0	0.2	0.7
Heel bone mineral density (BMD) T-score, automated (left)	1.7	3.8	6.7	-2.1	1.2	-1.8	1.8	2.6
Heel bone mineral density (BMD) T-score, automated (right)	1.7	3.8	8.5	-1.8	1.8	-1.1	1.7	2.9
Lung cancer (father)	1.7	2.0	3.6	-1.5	-0.2	-0.7	-1.8	-1.9
Osteoarthritis (self-reported)	1.7	2.2	4.3	1.2	2.1	1.5	0.8	1.6
Forced expiratory volume in 1-second (FEV1)	1.6	5.5	14.7	2.6	0.8	2.0	-1.2	-3.8
Risk taking	1.6	2.3	8.1	-0.4	-2.8	-1.2	1.3	-0.1
Height	1.5	29.7	70.4	8.4	3.3	6.2	3.8	-3.8
Sensitivity / hurt feelings	1.5	2.6	11.0	0.0	-0.4	0.0	1.4	3.3
Qualifications: None of the above	1.5	3.2	6.4	1.2	1.9	2.1	2.5	0.6
Standing height	1.5	14.5	37.9	6.2	1.0	4.4	2.5	-2.8
Birth weight of first child	1.5	2.8	5.6	2.4	1.2	2.1	-1.5	-0.1
Qualifications: College or University degree	1.5	4.8	7.2	-1.6	-2.7	-2.7	-2.6	-0.5
Pulse rate, automated reading	1.5	4.7	11.2	-0.8	-0.9	-1.2	-3.1	-3.3
Number of full sisters	1.5	1.8	3.3	-1.7	-1.0	-1.8	0.7	-1.2
Commuting to job workplace: Car/motor vehicle	1.5	1.7	3.1	-1.8	-1.7	-1.4	-0.6	-0.5
Commuting to job workplace: Public transport	1.5	1.8	5.6	2.4	0.5	1.4	0.1	1.2
High cholesterol (Self-reported)	1.5	2.7	7.7	2.2	0.5	2.8	0.9	-0.0
Reaction Time	1.4	2.7	5.5	-1.1	-1.6	-0.6	2.0	2.4
Breast Cancer	1.4	3.3	5.6	-2.1	-2.4	-1.8	-1.9	0.2
Fasting Glucose	1.4	1.7	3.0	1.2	1.7	1.7	-0.1	1.0
Medication: Ramipril	1.4	1.8	3.4	-1.9	-1.7	-1.2	-0.1	-1.2
Illnesses of siblings	1.4	1.9	7.6	-0.6	0.4	-0.4	2.8	1.2
Alcohol intake versus 10 years previously	1.4	2.1	7.0	-0.7	-2.6	0.2	1.8	0.1
Pulse wave Arterial Stiffness index	1.4	1.6	3.7	-0.9	-0.1	-0.7	-1.7	1.9
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	4.7	2.2	0.8	1.5	1.5	1.2
Guilty feelings	1.4	2.1	4.6	-0.8	-0.8	-1.2	-2.1	1.8
Wears glasses or contact lenses	1.4	1.6	4.5	1.0	2.1	0.9	-0.4	1.2
Mean Putamen Volume	1.3	1.5	2.5	-1.6	0.5	-1.5	-1.4	0.8
LDL Cholesterol	1.3	2.1	7.1	0.3	0.6	0.7	2.7	1.5
Waist Hip Ratio (WHR)	1.3	5.8	24.6	-0.7	-1.8	-0.5	-0.6	-5.0
Happiness	1.3	1.6	4.5	-0.8	0.4	-1.1	-2.1	1.1
Qualifications: A levels/AS levels or equivalent	1.3	2.9	6.2	-1.9	-1.9	-2.5	-1.1	0.0
Medication: Cholesterol lowering	1.3	2.0	5.1	2.1	0.1	2.3	-0.4	-0.7
Prospective memory result	1.3	1.5	3.4	-1.2	-1.8	-0.7	0.6	1.4
Loud music exposure frequency	1.3	1.4	7.0	0.1	0.3	-0.2	-0.2	2.6
Blood clot in the leg (DVT)	1.3	1.7	5.7	0.0	-1.6	0.2	2.4	0.5
Eye problems/disorders: None of the above	1.3	1.5	3.6	-1.9	0.1	-1.9	-0.1	0.5
Fractured/broken bones in last 5 years	1.3	1.7	4.3	2.1	0.7	1.6	-0.3	-1.0
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	6.3	0.3	-1.2	0.5	2.5	0.6
Coronary Artery Disease (CAD)	1.2	1.4	5.2	1.4	-0.2	0.2	2.3	-0.0
Type 2 Diabetes (T2D) (2012)	1.2	1.4	3.4	-1.2	1.0	-1.1	0.2	1.8
Ever had hysterectomy (womb removed)	1.2	1.4	3.1	0.7	1.8	0.9	1.6	0.0
Chronic bronchitis/emphysema (father)	1.2	1.4	5.7	0.2	-2.4	-0.2	-1.1	-0.3
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	3.8	-0.2	1.5	-0.6	1.0	1.9
Illnesses of mother	1.2	1.4	3.9	1.1	2.0	1.3	0.7	-0.2
Mineral and other dietary supplements	1.2	1.6	4.9	-1.1	-2.2	-1.1	0.1	-0.5
Medication: Paracetamol	1.2	1.8	3.0	1.2	1.7	1.3	1.3	1.1
Bipolar Disorder (2018)	1.1	1.8	4.4	-1.4	-0.9	-1.4	-2.1	0.4
Smoking Status	1.1	2.5	7.1	0.6	-0.5	1.0	-2.0	-2.7
Allergy or Eczema	1.1	3.0	8.1	-1.4	-1.6	-1.4	-2.8	-0.6
Hayfever, allergic rhinitis or eczema	1.1	2.4	5.5	-1.2	-2.1	-0.9	-2.4	-0.2
Past tobacco smoking	1.1	2.0	5.7	-0.9	-0.0	-1.1	1.5	2.4
Pain all over the body in last month	1.1	1.2	2.5	-1.6	-0.2	-1.4	0.2	1.2
Medication: Simvastatin	1.1	1.6	3.8	1.7	0.5	1.9	-0.5	-0.8
Tense / ‘highly strung’	1.1	1.9	7.0	-0.8	-2.6	-1.3	0.4	-0.2
Medication: Amlodipine	1.1	1.6	3.8	-0.8	-1.9	-0.3	-0.2	-2.0
High blood pressure (siblings)	1.1	1.5	4.3	0.3	0.1	0.7	-2.1	-1.6
Age at first live birth	1.1	2.0	3.6	-1.3	-1.9	-1.3	-1.4	-1.1
Health satisfaction	1.1	1.4	3.9	-1.1	-1.0	-0.9	-2.0	0.2
Loneliness, isolation	1.1	1.5	3.2	-0.8	-1.7	-0.9	0.5	1.8
Ever taken oral contraceptive pill	1.1	1.2	3.9	0.1	-2.0	-0.2	-0.7	-1.2
Medication: Blood pressure	1.1	2.1	6.2	0.6	-1.0	0.8	-1.5	-2.5
Supplements: Fish oil (including cod liver oil)	1.1	1.4	3.5	1.0	1.9	1.3	0.7	-0.3
Ovarian Cancer	1.0	1.3	3.5	-1.9	0.4	-1.2	-1.2	0.3
Rheumatoid Arthritis	1.0	1.4	3.6	0.1	1.9	0.8	1.4	0.9
Blood Eosinophil Count	1.0	7.4	30.0	0.8	-2.0	0.6	-5.5	-1.4
High blood pressure	1.0	2.9	8.3	-0.2	-1.5	0.7	-2.9	-1.8
Allergy	1.0	2.2	6.4	1.2	2.5	1.0	1.5	0.2
Medication: Blood pressure	1.0	1.7	2.9	-1.6	-1.1	-0.9	-1.7	-1.0
Medication: Ibuprofen	1.0	1.2	3.1	-0.3	1.7	-0.7	0.5	1.5
Mean time to correctly identify matches	1.0	1.9	3.9	-1.2	-0.1	-0.6	2.0	1.9
Hypertension (Self-reported)	1.0	2.7	7.5	-0.2	-1.2	0.6	-2.7	-2.0
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	4.4	2.1	-0.8	1.3	0.3	-1.9
Alzheimer’s Disease (including proxy)	0.9	1.2	4.3	-0.3	-0.7	-0.4	-2.1	1.1
Ulcerative Colitis (UC)	0.9	1.8	4.5	0.1	-2.1	-0.5	-2.0	-0.4
Blood Platelet Count	0.9	10.1	47.9	0.3	1.0	-1.1	-6.9	0.5
Blood White Count	0.9	7.0	25.1	0.4	0.7	0.7	-3.0	5.0
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.2	-1.2	-0.5	-0.9	1.0	1.5
Sitting height	0.9	6.3	17.6	4.2	1.5	2.7	1.2	-1.7
Medication: Paracetamol	0.9	1.4	3.7	0.7	1.0	0.8	1.9	1.1
Birth weight	0.9	1.9	4.5	1.9	-0.3	1.1	-0.2	-2.1
Exposure to tobacco smoke outside home	0.9	1.2	2.8	1.1	-0.0	1.7	1.4	0.2
Medication for pain relief, constipation, heartburn	0.9	1.6	4.0	0.3	-0.8	0.5	-1.7	-2.0
Eye problems/disorders: Glaucoma	0.9	1.0	2.5	1.2	0.9	1.6	0.4	0.6
Supplements: Calcium	0.9	1.0	2.1	-1.2	-0.4	-1.0	-0.6	1.4
Basal cell carcinoma (self-reported)	0.9	1.0	2.7	1.2	-0.1	1.0	-1.6	0.5
Ulcerative Colitis	0.8	1.2	2.6	-0.0	-1.6	-0.2	-1.3	1.2
Blood Red Count	0.8	7.3	9.5	2.7	2.4	2.9	3.1	2.3
Cardiovascular Disease	0.8	2.7	6.4	-0.4	-0.9	0.8	-2.4	-2.5
Lung FVC	0.8	3.9	8.7	1.2	0.7	1.0	-3.0	-2.8
Medication for hormone replacement therapy	0.8	0.9	2.3	0.1	1.2	0.5	-0.6	1.5
Maternal smoking around birth	0.8	1.2	2.6	0.6	1.3	0.4	-1.6	1.2
Relative age voice broke	0.8	1.2	2.2	-1.1	-0.4	-1.2	-1.5	0.9
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	1.8	-1.3	-1.3	-1.3	-0.5	1.0
Hip circumference	0.8	3.3	15.4	0.4	0.8	0.4	-0.1	3.9
Depression (self-reported)	0.8	1.0	3.2	0.1	1.8	0.5	1.2	-0.2
Overall health rating	0.8	1.8	4.6	-0.7	-2.1	-0.4	-1.3	1.4
Ever had bowel cancer screening	0.8	0.9	2.8	-0.9	-0.1	-0.9	0.2	1.7
Friendships satisfaction	0.8	0.9	2.7	0.8	0.6	0.9	-0.6	1.6
Average weekly champagne plus white wine intake	0.8	1.1	3.5	0.2	1.9	0.5	-0.1	-1.4
Vascular/heart problems diagnosed by doctor	0.8	2.3	6.8	0.8	1.3	-0.1	2.6	1.5
Crohns Disease (2012)	0.7	1.1	2.7	-1.0	-0.8	-1.0	-1.6	-0.6
Neuroticism	0.7	1.7	6.6	0.2	-0.4	0.3	1.3	2.6
Hearing difficulty/problems: Yes	0.7	1.0	2.4	-1.5	-0.7	-1.1	-0.4	0.9
Severe depression (siblings)	0.7	0.7	3.5	-0.2	-0.2	-0.2	-1.9	-0.3
Medication: Atenolol	0.7	0.9	3.0	-0.4	0.7	0.1	-0.8	-1.7
Hair/balding pattern: Pattern 2	0.7	0.9	3.2	0.1	1.8	0.2	0.7	0.8
Diabetes (self-reported)	0.7	1.0	4.0	-0.2	-2.0	-0.1	0.4	0.9
Neuroticism score	0.7	1.4	3.9	-0.1	-1.4	-0.3	1.0	2.0
Trunk fat-free mass	0.7	3.9	7.5	2.7	-0.1	2.4	1.2	-2.2
Hair/balding pattern: Pattern 3	0.7	1.1	4.0	0.1	-0.0	-0.3	-2.0	-1.1
Length of working week for main job	0.7	0.8	2.8	-0.5	-0.4	-0.8	-0.5	-1.7
Ever highly irritable/argumentative for 2 days	0.7	0.9	3.0	-0.8	0.4	-0.7	-1.7	0.3
Arm fat-free mass (right)	0.7	3.3	6.8	2.6	0.3	2.3	0.7	-2.0
Number of full brothers	0.7	0.8	2.4	1.5	0.2	1.1	-0.8	-0.1
Worry too long after embarrassment	0.7	1.2	2.6	-1.0	-1.1	-1.6	-0.3	1.0
Arm predicted mass (right)	0.7	3.7	7.8	2.8	0.4	2.4	0.8	-2.1
Smoking status: Previous	0.7	1.1	3.0	0.4	0.0	0.3	-1.4	-1.7
Whole body fat-free mass	0.7	3.7	7.6	2.8	-0.0	2.4	1.2	-1.9
Mood swings	0.7	1.3	3.4	-1.3	0.0	-1.0	0.3	1.8
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	2.9	0.1	-0.9	0.1	-1.7	-0.2
Number of self-reported non-cancer illnesses	0.7	1.2	2.8	-0.0	-1.7	0.6	-1.7	0.4
Medication: Bendroflumethiazide	0.7	1.1	3.1	-0.2	-1.8	0.2	0.0	-1.5
Medication: Atorvastatin	0.7	0.8	3.6	-0.6	-0.2	0.1	1.9	0.3
Illnesses of father: High blood pressure	0.7	0.9	1.9	1.2	1.4	1.0	0.1	-0.2
Ever smoked	0.7	1.2	3.1	1.3	0.6	1.8	-0.2	-0.8
Arm fat-free mass (left)	0.7	3.7	7.8	2.8	0.1	2.4	0.8	-2.0
Ever had prostate specific antigen (PSA) test	0.7	0.8	1.6	-0.1	1.2	0.9	0.5	1.2
Systolic Blood Pressure	0.6	3.0	9.9	0.1	-0.6	0.8	-2.0	-3.1
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.7	0.8	0.7	0.9	-0.5	1.3
Average weekly fortified wine intake	0.6	0.7	2.3	0.4	1.5	0.7	-0.2	-0.8
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	1.8	0.3	-1.3	0.2	0.2	-1.2
Serious illness, injury or assault to yourself	0.6	0.8	3.6	0.0	-0.2	-0.5	-1.9	0.2
High blood pressure (mother)	0.6	0.9	2.4	0.8	-0.1	0.9	-0.6	-1.6
Nervous feelings	0.6	1.2	3.2	-0.7	-0.9	-0.7	1.0	1.8
Hearing difficulty/problems with background noise	0.6	1.0	2.2	-1.1	-0.9	-0.9	0.3	1.5
Medication: Lansoprazole	0.6	0.7	1.6	0.7	0.8	0.7	-1.3	0.0
Trunk predicted mass	0.6	3.7	7.2	2.7	-0.0	2.3	1.2	-2.1
Pulse wave reflection index	0.6	0.8	1.3	-1.1	-0.9	-0.8	-1.1	-0.0
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	1.5	0.6	1.2	0.6	-1.1	-0.6
Headache pain in last month	0.6	1.0	4.9	0.3	0.5	0.1	-0.1	2.2
Gout (self-reported)	0.6	0.8	2.2	-0.7	-1.0	-0.6	-1.5	0.4
Comparative body size at age 10	0.6	1.6	4.5	-1.0	0.6	-0.6	-2.1	-1.4
Chest pain or discomfort	0.6	0.8	1.6	1.2	0.4	1.3	-0.6	-0.6
Leg fat-free mass (right)	0.6	3.1	6.4	2.5	-0.2	2.1	1.2	-1.7
Long-standing illness, disability or infirmity	0.6	1.0	4.2	0.3	-2.1	0.3	-0.6	-0.2
Diabetes diagnosed by doctor	0.6	1.0	3.5	-0.3	-1.9	-0.1	0.8	0.8
Commuting to job workplace: Walk	0.6	0.7	2.8	-0.4	0.5	-0.3	-1.7	0.4
Whole body water mass	0.6	3.5	7.1	2.7	-0.1	2.3	1.2	-1.9
Leg predicted mass (right)	0.6	3.1	6.5	2.5	-0.2	2.1	1.1	-1.8
Miserableness	0.6	1.0	1.9	1.0	-0.2	0.9	1.4	1.1
Average weekly beer plus cider intake	0.6	0.8	2.0	1.0	-0.4	1.0	-0.0	1.4
Myopia	0.6	0.9	2.6	1.6	-1.0	0.8	0.0	-0.1
Arm predicted mass (left)	0.6	3.0	6.9	2.6	0.1	2.1	0.9	-1.6
Bipolar Disorder or Schizophrenia	0.5	1.3	1.9	-1.4	-0.8	-1.1	-1.0	-1.3
Schizophrenia vs Biploar Disorder	0.5	0.7	2.2	0.7	-0.1	0.6	1.5	-0.6
Alzheimer’s Disease (in mother)	0.5	0.6	2.4	-0.1	0.0	-0.1	-1.6	0.6
HbA1C	0.5	0.6	1.5	0.0	1.2	-0.0	-0.2	-1.2
Hypothyroidism (self reported)	0.5	1.0	2.1	-0.6	0.3	-1.2	1.0	1.5
Chronotype (morning person)	0.5	1.1	3.2	-1.8	0.2	-1.0	-0.2	1.1
Number of treatments/medications taken	0.5	0.8	1.8	1.1	-0.8	1.3	-0.4	0.6
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.4	-0.5	-1.6	-0.4	-0.3	0.7
Medication: Metformin	0.5	0.6	3.1	0.2	0.2	0.0	1.8	0.2
Leg fat-free mass (left)	0.5	2.5	5.2	2.3	-0.2	2.0	1.2	-1.3
Trunk fat percentage	0.5	2.2	6.6	0.6	1.6	0.9	0.7	2.6
Townsend deprivation index at recruitment	0.5	0.7	2.5	0.3	-1.6	0.3	-0.8	0.6
Supplements: Glucosamine	0.5	0.6	2.9	0.1	1.7	-0.2	-0.4	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.4	0.7	0.8	0.3	-1.2	-0.5
Impedance of arm (left)	0.5	2.1	4.8	1.0	1.5	0.3	1.6	2.2
Number of children fathered	0.5	0.6	1.4	-0.7	1.2	-0.8	-0.2	-0.4
Emphysema/chronic bronchitis	0.5	0.6	1.7	0.5	-1.3	0.5	-0.3	-0.9
Had major operations	0.5	0.6	1.1	-1.1	-0.9	-0.9	-0.0	0.0
Illnesses of father: Heart disease	0.5	0.6	1.9	0.8	0.4	0.5	-0.5	-1.4
Qualifications: nursing, teaching	0.5	0.7	2.0	-1.4	-0.5	-1.1	-0.3	0.4
Eye problems/disorders: Cataract	0.5	0.6	1.1	1.1	-0.4	0.8	1.0	0.2
Pain type(s) experienced in last month: Hip pain	0.5	0.7	1.4	0.6	1.2	0.3	-0.8	1.0
Basal metabolic rate	0.5	3.0	6.3	2.5	0.1	2.2	1.1	-1.5
Irritability	0.5	0.8	1.8	1.1	-0.5	1.3	0.8	0.1
Diastolic blood pressure, automated reading	0.5	1.5	2.4	1.4	0.8	1.2	-1.1	-1.6
Heart disease (siblings)	0.5	0.6	1.5	1.2	0.3	1.2	-0.1	-0.3
Schizophrenia (2018)	0.4	0.9	3.8	-0.6	-0.2	-0.3	0.4	-2.0
Body Mass Index (BMI) (2010)	0.4	0.6	1.0	-1.0	-0.7	-0.9	-0.8	0.3
BMI	0.4	2.3	6.2	-2.5	0.9	-1.2	-0.4	1.7
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.1	-0.7	-1.1	-0.7	0.8	0.8
Relative age of first facial hair	0.4	0.7	2.9	-0.1	-0.6	-0.6	-1.7	0.3
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.0	0.5	0.3	0.6	1.0	0.4
Qualifications: CSEs or equivalent	0.4	0.6	1.4	-0.2	-1.2	-0.4	-0.3	-1.2
Medication: Levothyroxine sodium	0.4	0.7	2.2	0.4	1.0	-0.0	0.6	1.5
Leg predicted mass (left)	0.4	2.4	4.8	2.2	-0.2	2.0	1.3	-1.2
Heart attack	0.4	0.5	1.0	-0.9	0.6	-0.8	-1.0	-0.0
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	2.2	0.0	-0.6	-0.1	-1.5	0.7
Worrier / anxious feelings	0.4	0.7	2.0	0.4	-1.0	0.3	-0.2	1.4
Number of live births	0.4	0.6	1.8	-0.1	1.3	-0.2	0.8	0.6
Asthma	0.4	0.8	2.2	-0.8	-1.5	-0.6	-0.5	0.5
Glaucoma (self-reported)	0.4	0.4	1.4	0.8	-0.3	1.2	0.2	0.2
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.0	0.4	0.3	0.9	1.0	0.8
Body fat percentage	0.4	1.5	6.2	-0.1	1.0	0.5	0.2	2.5
Leg fat percentage (right)	0.4	1.5	4.4	-1.2	0.4	-0.3	-1.1	2.1
Wheeze or whistling in the chest in last year	0.4	0.7	2.3	0.6	-0.6	0.2	-1.5	0.7
Medication: Allopurinol	0.4	0.5	1.1	-0.1	-1.0	0.2	-0.6	1.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.8	-0.1	-0.2	0.3	1.3	-0.7
Illnesses of siblings: Diabetes	0.4	0.4	1.6	-0.2	0.2	-0.5	-1.3	-0.5
Medication for cholesterol	0.4	0.5	1.8	-0.6	0.1	-1.4	0.4	0.5
Medication: Gliclazide	0.4	0.5	1.4	-0.3	-0.2	0.1	0.9	1.2
Smoking status: Current	0.4	0.6	2.2	-0.3	-0.8	0.1	-0.6	-1.5
Number of operations (self-reported)	0.4	0.6	1.6	-0.5	1.3	-0.5	-0.9	0.5
Depressed Affect (Nagel 2018)	0.3	0.6	2.4	0.0	-0.1	0.3	0.7	1.5
Intelligence (Savage-Jansen 2018)	0.3	1.0	2.4	-1.1	-0.4	-1.6	-1.1	-0.4
Neuroticism (Nagel 2018)	0.3	0.6	1.5	-0.2	-1.2	-0.4	-0.3	1.1
Major Depression (MDD)	0.3	0.4	0.9	-0.1	0.2	0.7	0.7	-0.9
Neuroticism (2016)	0.3	0.5	1.5	0.3	-1.2	0.2	0.8	-0.1
Respiratory disease	0.3	0.6	2.5	-0.0	-1.6	0.1	-0.8	-0.1
Lung FEV1/FVC ratio	0.3	1.5	3.8	-1.9	-0.7	-1.7	0.1	-0.7
Systolic blood pressure, automated reading	0.3	0.9	2.2	0.5	0.4	1.5	-1.2	-0.8
Angina	0.3	0.3	0.5	-0.7	0.7	-0.2	-0.6	0.4
Current tobacco smoking	0.3	0.5	0.7	-0.7	-0.8	-0.3	-0.8	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.8	0.1	-1.3	-0.3	-0.1	-0.1
Stomach or abdominal pain in last month	0.3	0.3	1.1	0.5	0.3	0.5	1.0	0.2
Impedance of leg (left)	0.3	1.3	4.2	1.1	2.0	0.5	-0.6	0.8
Trunk fat mass	0.3	1.5	2.5	1.1	1.3	1.3	0.7	1.6
Impedance of arm (right)	0.3	1.4	4.3	0.8	0.7	0.1	1.3	2.1
Arm fat percentage (right)	0.3	1.2	5.1	-0.9	0.2	-0.1	0.1	2.3
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	0.9	0.9	-0.6	0.8	0.1	-0.7
Falls in the last year	0.3	0.4	0.9	0.5	0.9	0.3	-0.1	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.4	0.3	-0.0	0.6	1.2	0.5
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	0.8	0.8	0.5	0.5	-0.5	-0.9
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.6	0.1	0.4	-0.3	1.3	0.8
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.9	-0.2	0.5	-0.6	0.8	1.4
Mouth/teeth dental problems: Loose teeth	0.3	0.3	0.9	-0.0	-0.9	-0.6	-0.7	-0.1
Angina (self-reported)	0.3	0.3	0.6	-0.7	0.8	-0.2	-0.6	0.3
Heart disease (mother)	0.3	0.3	0.7	-0.6	-0.8	-0.1	0.4	-0.7
Whole body fat mass	0.3	1.3	2.2	1.0	1.0	1.4	0.6	1.5
Supplements: Vitamin C	0.3	0.3	0.9	-0.1	0.7	0.5	-0.9	0.3
Arm fat percentage (left)	0.3	1.0	4.3	-0.8	0.3	-0.0	-0.1	2.1
Back pain experienced in last month	0.3	0.5	0.8	0.9	0.5	0.9	0.6	0.5
Asthma (self-reported)	0.3	0.7	2.3	-0.6	-1.5	-0.4	-0.6	0.4
Mother’s age at death	0.3	0.4	0.8	-0.6	-0.7	-0.5	-0.3	-0.9
Financial situation satisfaction	0.3	0.4	1.0	0.7	-0.4	0.2	-0.7	1.0
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.0	-1.0	0.8	-0.5	-0.4	0.1
Medication: Lisinopril	0.3	0.3	0.7	0.5	0.5	0.2	-0.8	-0.7
Leg fat percentage (left)	0.3	1.2	3.1	-1.0	0.6	-0.2	-1.2	1.8
Age started oral contraceptive pill	0.3	0.4	1.5	-0.2	-0.6	-0.4	1.2	-0.3
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.9	-0.7	0.7	-0.6	-0.9	-0.1
Impedance of whole body	0.3	1.5	3.0	1.3	1.6	0.4	0.6	1.7
Depression (Nagel 2018)	0.2	0.2	0.5	-0.5	-0.1	-0.6	-0.7	0.3
Worry (Nagel 2018)	0.2	0.4	1.4	-0.0	-1.2	-0.5	0.0	0.4
Alzheimer’s Disease (in father)	0.2	0.2	0.4	0.4	-0.6	0.3	-0.7	-0.2
Prostate Cancer	0.2	0.3	0.8	0.1	-0.8	-0.0	-0.9	-0.3
Primary Biliary Cirrhosis	0.2	0.4	0.6	0.2	-0.8	0.7	-0.3	-0.7
Schizophrenia (2014)	0.2	0.5	1.0	-1.0	-0.3	-0.8	-0.5	-0.7
Triglycerides	0.2	0.4	0.6	-0.7	-0.0	-0.6	-0.8	-0.6
Hair Pigment	0.2	5.3	15.3	-0.3	-2.1	-0.1	-2.6	-3.9
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.7	0.5	0.8	0.4	0.0	-0.5
Impedance of leg (right)	0.2	1.1	3.3	0.5	1.8	0.2	-0.2	1.4
Fed-up feelings	0.2	0.3	0.7	0.5	-0.8	0.6	-0.3	0.5
Taking other prescription medications	0.2	0.3	0.5	0.4	-0.6	0.7	-0.3	0.6
Age when periods started (menarche)	0.2	0.4	0.8	-0.3	-0.9	-0.3	-0.9	0.5
Body mass index (BMI)	0.2	0.6	1.7	-1.3	0.0	-0.4	-0.5	1.1
Had menopause	0.2	0.3	0.8	-0.0	0.9	-0.6	-0.5	0.4
Had other major operations	0.2	0.2	0.6	0.5	0.8	0.2	0.1	-0.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.8	0.4	0.9	0.1	-0.0	-0.5
Fluid intelligence score	0.2	0.5	2.2	0.3	1.5	-0.1	-0.3	-0.5
Weight	0.2	1.1	2.6	1.6	0.4	1.6	0.5	-0.3
Time employed in main current job	0.2	0.2	0.5	0.3	-0.7	0.1	0.5	-0.2
Father’s age at death	0.2	0.3	0.8	0.2	-0.9	0.1	0.8	0.1
Noisy workplace	0.2	0.3	0.6	-0.8	-0.8	-0.3	0.3	-0.3
Exposure to tobacco smoke at home	0.2	0.2	0.8	0.3	-0.4	-0.0	-0.9	-0.4
Hair/balding pattern: Pattern 4	0.2	0.6	1.5	-0.7	-1.2	0.0	-0.7	-0.6
Chronic bronchitis/emphysema (mother)	0.2	0.3	0.5	-0.3	-0.5	-0.7	0.4	0.6
Shortness of breath walking on level ground	0.2	0.2	0.7	-0.2	-0.3	-0.5	-0.2	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.6	0.8	0.0	0.4	0.4	-0.1
Suffer from ‘nerves’	0.2	0.3	0.5	0.7	-0.6	0.2	0.7	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.5	-0.7	-0.1	-0.6	-0.3	0.5
Osteoporosis (self-reported)	0.2	0.3	1.2	0.1	-0.2	-0.1	-1.1	-0.4
Illnesses of father: None of the above (group 1)	0.2	0.3	0.8	-0.9	0.1	-0.7	0.3	-0.0
Ever depressed for a whole week	0.2	0.3	0.5	-0.6	-0.5	-0.5	-0.7	0.1
Commuting to job workplace: Cycle	0.2	0.3	0.6	0.3	-0.2	0.0	-0.8	-0.8
Pack years of smoking	0.2	0.3	0.6	0.2	-0.3	0.7	0.7	0.5
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.3	-0.3	0.6	-0.5	0.4	0.5
Age at First Birth	0.1	0.1	0.3	0.4	-0.3	0.6	-0.0	-0.4
Heel T-Score	0.1	1.2	2.5	-1.6	0.3	-0.8	1.4	0.9
Vitamin and mineral supplements	0.1	0.1	0.2	0.2	-0.5	-0.4	0.0	-0.3
Diabetes (father)	0.1	0.2	0.3	-0.1	-0.4	0.2	0.4	0.6
Diabetes (mother)	0.1	0.1	0.3	-0.0	0.6	0.0	-0.6	0.2
Pack years adult smoking proportion	0.1	0.1	0.4	-0.1	-0.6	0.4	0.1	0.2
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.4	-0.2	0.2	0.0	0.2	-0.6
Multivitamins +/- minerals	0.1	0.1	0.3	-0.5	0.5	-0.1	0.3	0.2
Waist circumference	0.1	0.3	0.8	-0.4	-0.3	0.1	-0.8	0.9
Number of incorrect matches in round	0.1	0.2	0.5	-0.2	-0.5	-0.0	-0.4	0.7
Arm fat mass (right)	0.1	0.4	1.3	0.1	0.5	0.6	0.3	1.1
Medication: Seretide 50 evohaler	0.1	0.1	0.3	-0.4	0.1	-0.3	-0.4	0.5
Leg fat mass (right)	0.1	0.4	1.2	0.1	0.6	0.7	-0.4	1.1
Age at last live birth	0.1	0.1	0.6	-0.3	-0.8	-0.0	-0.1	0.1
Breast cancer (self-reported)	0.1	0.1	0.3	0.6	0.2	0.2	0.5	-0.4
Arm fat mass (left)	0.1	0.5	1.4	0.3	0.4	0.8	0.3	1.2
Unable to work because of sickness or disability	0.1	0.1	0.1	-0.0	0.2	0.3	0.4	0.4
Cholesterol lowering medication	0.1	0.2	0.5	-0.2	0.0	0.5	0.7	0.1
Leg fat mass (left)	0.1	0.5	0.8	0.3	0.7	0.9	-0.4	0.9
Tanning	0.0	0.5	1.1	0.7	0.2	0.8	0.3	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.1	0.1	-0.2	0.2	0.1	0.2	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.0	0.1	-0.2	-0.2	-0.0	0.0	-0.3

Hub : Genes

FNBP1L

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Trait associations