[Hub]/) : Traits : Height : ← →

chr6:79,646,575-85,117,025

Best TWAS P=1.02e-91 · Best GWAS P=2.22e-77 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	BCKDHB	0.11	0.09	bslmm	563	0.09	1.1e-10	11.1	8.1	3.9e-16	-0.32	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SH3BGRL2	0.11	0.18	lasso	1	0.18	1.7e-21	5.1	5.1	3.0e-07	-0.14	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	SNAP91	0.09	0.05	lasso	3	0.08	1.6e-09	7.7	7.4	1.8e-13	-0.01	0.96	0.04	TRUE
4	CommonMind	Brain Pre-frontal Cortex	TTK	0.07	0.00	bslmm	472	0.02	3.8e-03	-2.6	-7.4	1.2e-13	0.21	0.13	0.05	FALSE
5	GTEx	Adipose Subcutaneous	DOPEY1	0.29	0.27	lasso	6	0.28	4.2e-23	8.6	-9.1	8.7e-20	0.02	0.45	0.55	FALSE
6	GTEx	Adipose Subcutaneous	RP11-250B2.6	0.07	0.04	lasso	4	0.05	4.4e-05	11.5	-5.7	1.6e-08	0.26	0.67	0.01	FALSE
7	GTEx	Adipose Visceral Omentum	DOPEY1	0.20	0.18	enet	11	0.20	1.1e-10	8.6	-9.1	1.2e-19	0.03	0.22	0.77	FALSE
8	GTEx	Adipose Visceral Omentum	RP11-250B2.3	0.13	0.00	enet	13	0.01	8.2e-02	-6.7	-9.3	2.1e-20	0.23	0.06	0.05	FALSE
9	GTEx	Adipose Visceral Omentum	RP11-250B2.6	0.16	0.05	lasso	6	0.06	7.8e-04	16.3	-17.0	5.9e-65	0.55	0.36	0.09	FALSE
10	GTEx	Artery Aorta	DOPEY1	0.36	0.20	enet	34	0.25	5.4e-14	8.6	-7.8	7.0e-15	-0.02	0.35	0.65	FALSE
11	GTEx	Artery Aorta	BCKDHB	0.14	0.14	lasso	1	0.13	9.8e-08	11.0	11.0	3.9e-28	-0.28	1.00	0.00	FALSE
12	GTEx	Artery Aorta	ELOVL4	0.11	0.13	lasso	2	0.11	1.7e-06	8.3	8.1	4.3e-16	-0.39	0.95	0.00	FALSE
13	GTEx	Artery Coronary	BCKDHB	0.29	0.05	lasso	27	0.11	1.7e-04	11.1	9.4	3.4e-21	-0.23	0.41	0.03	FALSE
14	GTEx	Artery Tibial	DOPEY1	0.33	0.28	lasso	7	0.30	2.0e-23	8.6	-9.2	4.8e-20	0.02	0.48	0.52	FALSE
15	GTEx	Artery Tibial	BCKDHB	0.16	0.16	lasso	11	0.15	4.9e-12	11.1	10.3	5.0e-25	-0.28	1.00	0.00	FALSE
16	GTEx	Artery Tibial	ELOVL4	0.13	0.12	lasso	8	0.10	2.0e-08	7.6	7.2	6.7e-13	-0.40	1.00	0.00	FALSE
17	GTEx	Brain Caudate basal ganglia	BCKDHB	0.21	-0.01	enet	53	0.00	4.5e-01	-15.6	5.2	1.9e-07	-0.42	0.10	0.06	FALSE
18	GTEx	Brain Caudate basal ganglia	UBE3D	0.29	0.28	lasso	2	0.26	5.9e-08	9.1	9.1	8.2e-20	0.01	0.01	0.99	FALSE
19	GTEx	Brain Cerebellar Hemisphere	RP11-250B2.3	0.30	0.05	enet	32	0.12	5.2e-04	-15.6	-6.4	1.3e-10	0.47	0.14	0.08	TRUE
20	GTEx	Brain Cerebellum	RP11-250B2.5	0.43	0.11	lasso	5	0.14	4.7e-05	-16.7	-16.4	1.8e-60	0.53	0.43	0.04	FALSE
21	GTEx	Brain Putamen basal ganglia	UBE3D	0.40	0.21	lasso	5	0.21	9.5e-06	9.1	9.0	2.1e-19	0.01	0.01	0.97	FALSE
22	GTEx	Breast Mammary Tissue	DOPEY1	0.32	0.18	enet	29	0.16	1.2e-08	8.6	-8.4	5.4e-17	0.00	0.15	0.85	FALSE
23	GTEx	Breast Mammary Tissue	RP11-250B2.3	0.13	0.06	lasso	4	0.04	2.6e-03	-6.7	-7.5	6.1e-14	0.34	0.16	0.04	FALSE
24	GTEx	Breast Mammary Tissue (Male)	RP11-250B2.6	0.12	0.00	enet	10	0.00	3.9e-01	13.3	8.8	1.0e-18	0.16	0.06	0.06	FALSE
25	GTEx	Breast Mammary Tissue (Female)	DOPEY1	0.31	0.14	lasso	5	0.07	4.5e-03	8.6	-8.4	5.0e-17	0.02	0.04	0.66	FALSE
26	GTEx	Breast Mammary Tissue (Female)	RP11-250B2.3	0.16	0.06	enet	11	0.04	2.4e-02	15.4	-10.0	1.3e-23	0.49	0.12	0.06	TRUE
27	GTEx	Breast Mammary Tissue (Female)	RP11-250B2.5	0.08	-0.01	lasso	4	-0.01	7.0e-01	-15.0	-7.8	4.9e-15	0.31	0.06	0.05	TRUE
28	GTEx	Cells EBV-transformed lymphocytes	RP11-250B2.6	0.21	0.03	enet	37	0.13	4.7e-05	11.1	-13.1	4.9e-39	0.14	0.14	0.05	FALSE
29	GTEx	Cells Transformed fibroblasts	DOPEY1	0.17	0.14	enet	16	0.17	1.8e-12	8.6	-9.8	9.7e-23	0.00	0.05	0.95	FALSE
30	GTEx	Cells Transformed fibroblasts	BCKDHB	0.16	0.02	enet	42	0.04	3.7e-04	11.4	17.2	1.2e-66	-0.55	0.50	0.28	FALSE
31	GTEx	Cells Transformed fibroblasts	ELOVL4	0.09	0.05	lasso	7	0.06	2.8e-05	6.4	6.4	1.8e-10	-0.25	0.33	0.02	FALSE
32	GTEx	Cells Transformed fibroblasts	RP11-250B2.5	0.16	0.07	lasso	10	0.05	5.8e-05	15.8	7.8	6.3e-15	-0.01	0.59	0.02	TRUE
33	GTEx	Cells Transformed fibroblasts	RP11-250B2.6	0.11	0.01	lasso	7	0.00	1.4e-01	-15.5	-10.5	6.2e-26	0.57	0.38	0.02	TRUE
34	GTEx	Colon Sigmoid	DOPEY1	0.19	0.21	lasso	6	0.21	5.6e-08	8.8	-9.2	5.2e-20	0.01	0.02	0.98	FALSE
35	GTEx	Colon Transverse	DOPEY1	0.14	0.13	enet	7	0.12	2.3e-06	8.6	-9.3	1.3e-20	0.02	0.12	0.81	FALSE
36	GTEx	Colon Transverse	RP11-250B2.5	0.13	0.02	enet	3	0.01	6.3e-02	-6.7	-12.9	3.5e-38	0.50	0.11	0.08	TRUE
37	GTEx	Colon Transverse	RP11-250B2.6	0.15	0.16	lasso	2	0.13	9.8e-07	11.4	-10.4	2.1e-25	0.27	0.95	0.00	FALSE
38	GTEx	Esophagus Gastroesophageal Junction	DOPEY1	0.19	0.11	lasso	5	0.08	6.0e-04	8.6	-9.0	3.1e-19	0.02	0.06	0.80	FALSE
39	GTEx	Esophagus Mucosa	BCKDHB	0.17	0.16	lasso	6	0.15	3.9e-10	7.9	-7.4	1.6e-13	0.37	0.99	0.01	FALSE
40	GTEx	Esophagus Mucosa	RP11-250B2.6	0.20	0.16	lasso	7	0.23	3.3e-15	-15.5	-16.9	9.0e-64	0.65	1.00	0.00	FALSE
41	GTEx	Esophagus Muscularis	DOPEY1	0.25	0.15	enet	10	0.14	1.4e-08	8.6	-8.2	3.1e-16	0.02	0.46	0.54	FALSE
42	GTEx	Esophagus Muscularis	BCKDHB	0.18	0.07	enet	25	0.06	2.4e-04	11.0	9.5	1.9e-21	-0.28	0.94	0.00	FALSE
43	GTEx	Esophagus Muscularis	ELOVL4	0.16	0.05	enet	18	0.11	3.4e-07	9.0	6.7	2.2e-11	-0.30	0.92	0.00	FALSE
44	GTEx	Heart Atrial Appendage	RP11-250B2.6	0.20	0.00	enet	17	0.03	2.6e-02	-10.3	-20.3	1.0e-91	0.32	0.08	0.22	TRUE
45	GTEx	Heart Left Ventricle	RP11-250B2.6	0.09	0.00	enet	6	0.02	2.0e-02	15.8	-15.3	6.5e-53	0.59	0.16	0.09	FALSE
46	GTEx	Lung	DOPEY1	0.11	0.13	lasso	3	0.12	2.9e-09	8.6	-8.6	7.1e-18	0.02	0.48	0.52	FALSE
47	GTEx	Lung	BCKDHB	0.09	0.06	enet	10	0.05	1.8e-04	11.0	11.0	2.7e-28	-0.28	0.91	0.01	FALSE
48	GTEx	Lung	UBE3D	0.07	0.01	enet	16	0.02	9.8e-03	6.9	5.4	6.7e-08	0.01	0.06	0.55	FALSE
49	GTEx	Lung	RP11-250B2.6	0.09	0.05	enet	16	0.07	5.3e-06	11.5	-17.4	1.8e-67	0.38	0.70	0.18	FALSE
50	GTEx	Muscle Skeletal	DOPEY1	0.13	0.11	lasso	5	0.10	4.2e-10	8.6	-8.8	1.7e-18	0.02	0.48	0.52	FALSE
51	GTEx	Muscle Skeletal	RP11-250B2.6	0.07	0.04	lasso	5	0.04	4.2e-05	16.6	-17.4	7.1e-68	0.67	0.90	0.05	FALSE
52	GTEx	Nerve Tibial	DOPEY1	0.23	0.28	lasso	3	0.28	3.7e-20	8.6	-8.8	9.0e-19	0.02	0.48	0.52	FALSE
53	GTEx	Nerve Tibial	BCKDHB	0.18	0.11	lasso	9	0.10	2.4e-07	11.1	11.4	5.1e-30	-0.28	1.00	0.00	FALSE
54	GTEx	Nerve Tibial	SH3BGRL2	0.18	0.02	lasso	5	0.04	1.4e-03	9.0	5.2	1.6e-07	-0.29	0.27	0.13	FALSE
55	GTEx	Ovary	DOPEY1	0.33	0.19	enet	18	0.23	2.9e-06	8.6	-9.9	4.7e-23	0.04	0.07	0.90	TRUE
56	GTEx	Skin Not Sun Exposed Suprapubic	RP11-250B2.3	0.12	0.11	lasso	4	0.15	1.1e-08	15.4	-5.5	3.0e-08	0.31	0.86	0.01	FALSE
57	GTEx	Skin Not Sun Exposed Suprapubic	RP11-250B2.5	0.13	0.16	lasso	4	0.17	1.1e-09	15.4	-9.6	6.9e-22	0.48	0.98	0.00	FALSE
58	GTEx	Skin Not Sun Exposed Suprapubic	RP11-250B2.6	0.08	0.05	lasso	4	0.01	8.1e-02	11.5	-10.1	5.5e-24	0.25	0.22	0.03	FALSE
59	GTEx	Skin Sun Exposed Lower leg	DOPEY1	0.16	0.17	lasso	5	0.16	4.0e-13	8.8	-9.2	5.6e-20	0.01	0.15	0.85	FALSE
60	GTEx	Skin Sun Exposed Lower leg	RP11-250B2.3	0.12	0.06	enet	29	0.07	2.5e-06	15.4	-7.1	1.2e-12	0.54	0.80	0.17	TRUE
61	GTEx	Skin Sun Exposed Lower leg	RP11-250B2.5	0.09	0.03	enet	34	0.06	4.6e-06	16.7	-7.8	5.4e-15	0.49	0.79	0.10	FALSE
62	GTEx	Spleen	DOPEY1	0.21	0.12	lasso	4	0.12	7.1e-04	7.7	-8.0	1.0e-15	-0.01	0.18	0.24	FALSE
63	GTEx	Stomach	RP11-250B2.6	0.13	0.15	lasso	6	0.12	2.5e-06	11.4	-10.2	2.1e-24	0.25	0.94	0.00	FALSE
64	GTEx	Testis	DOPEY1	0.19	0.00	lasso	9	0.03	2.4e-02	7.1	-7.4	1.5e-13	0.00	0.08	0.57	FALSE
65	GTEx	Testis	ELOVL4	0.31	0.19	lasso	7	0.18	1.9e-08	-8.1	-7.4	9.9e-14	0.13	0.96	0.00	TRUE
66	GTEx	Testis	RP11-250B2.5	0.13	0.17	lasso	3	0.14	7.0e-07	-15.4	-14.9	2.8e-50	0.72	0.81	0.02	FALSE
67	GTEx	Testis	RP11-250B2.6	0.09	0.05	lasso	6	0.04	6.9e-03	11.5	-10.8	2.0e-27	0.29	0.42	0.03	FALSE
68	GTEx	Thyroid	BCKDHB	0.17	0.06	lasso	8	0.10	3.4e-08	11.5	14.2	6.4e-46	-0.50	1.00	0.00	TRUE
69	GTEx	Thyroid	RP11-250B2.6	0.11	0.10	lasso	2	0.07	3.2e-06	11.4	-11.4	2.6e-30	0.27	1.00	0.00	FALSE
70	METSIM	Adipose	BCKDHB	0.05	0.03	blup	558	0.05	1.1e-07	-15.4	9.6	9.2e-22	-0.54	1.00	0.00	FALSE
71	METSIM	Adipose	DOPEY1	0.08	0.08	lasso	10	0.07	2.4e-10	8.6	-9.3	1.4e-20	0.01	0.16	0.84	FALSE
72	METSIM	Adipose	ELOVL4	0.06	0.03	bslmm	500	0.04	3.2e-06	7.6	8.4	6.0e-17	-0.42	1.00	0.00	FALSE
73	METSIM	Adipose	RP11-250B2.5	0.03	0.03	lasso	4	0.01	3.5e-03	5.6	5.6	2.0e-08	0.09	0.37	0.03	TRUE
74	METSIM	Adipose	RP11-250B2.6	0.04	0.04	lasso	12	0.02	1.7e-04	16.7	-14.7	8.8e-49	0.61	0.73	0.02	FALSE
75	ROSMAP	Brain Pre-frontal Cortex	DOPEY1	0.11	0.08	enet	45	0.09	2.9e-11	6.8	-6.9	6.4e-12	0.00	1.00	0.00	FALSE
76	ROSMAP	Brain Pre-frontal Cortex	BCKDHB	0.18	0.13	lasso	6	0.14	2.9e-17	11.1	8.8	1.8e-18	-0.31	1.00	0.00	FALSE
77	ROSMAP	Brain Pre-frontal Cortex	FAM46A	0.08	0.01	blup	495	0.03	2.7e-04	7.1	9.5	1.7e-21	-0.01	0.65	0.01	TRUE
78	ROSMAP	Brain Pre-frontal Cortex	SH3BGRL2	0.10	0.10	lasso	3	0.10	2.0e-12	5.1	5.2	1.8e-07	-0.14	1.00	0.00	TRUE
79	ROSMAP	Brain Pre-frontal Cortex	RP11-250B2.3	0.08	0.02	blup	402	0.04	5.8e-06	10.9	-7.7	1.5e-14	0.22	0.79	0.02	TRUE
80	YFS	Blood	BCKDHB	0.01	0.01	blup	557	0.00	1.3e-02	9.3	6.9	3.9e-12	-0.44	0.28	0.13	FALSE
81	YFS	Blood	DOPEY1	0.18	0.21	lasso	9	0.21	1.4e-67	8.6	-9.0	2.0e-19	0.03	0.49	0.51	FALSE
82	YFS	Blood	RWDD2A	0.02	0.01	bslmm	347	0.00	8.2e-03	7.1	-5.2	2.0e-07	0.03	0.88	0.01	FALSE
83	The Cancer Genome Atlas	Breast Invasive Carcinoma	DOPEY1	0.05	0.06	lasso	2	0.06	2.6e-12	8.6	-9.0	3.0e-19	0.02	0.02	0.98	FALSE
84	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BCKDHB	0.12	0.06	lasso	4	0.06	4.2e-07	14.7	-12.2	1.8e-34	0.45	0.98	0.00	FALSE
85	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DOPEY1	0.09	0.02	enet	3	0.04	2.4e-05	8.6	-7.4	1.1e-13	0.02	0.01	0.99	FALSE
86	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DOPEY1	0.08	0.08	blup	47	0.09	2.3e-10	8.6	-9.0	2.2e-19	0.04	0.01	0.99	FALSE
87	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ELOVL4	0.09	0.04	enet	4	0.02	1.9e-03	9.1	8.9	5.2e-19	-0.47	0.00	1.00	FALSE
88	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RWDD2A	0.14	0.01	blup	31	0.01	9.1e-03	7.1	-5.2	1.6e-07	-0.04	0.00	0.22	FALSE
89	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	DOPEY1	0.06	0.08	lasso	2	0.04	3.9e-03	8.9	-9.0	1.8e-19	0.01	0.00	0.93	FALSE
90	The Cancer Genome Atlas	Lung Adenocarcinoma	DOPEY1	0.03	0.02	lasso	2	0.02	2.1e-03	8.6	-8.9	5.2e-19	0.02	0.01	0.89	FALSE
91	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DOPEY1	0.07	0.05	lasso	3	0.04	8.7e-06	8.6	-8.6	7.1e-18	0.02	0.02	0.97	FALSE
92	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	DOPEY1	0.08	0.05	blup	47	0.04	1.4e-03	8.7	-8.2	3.1e-16	0.03	0.01	0.92	FALSE
93	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DOPEY1	0.17	0.16	lasso	3	0.14	1.6e-06	8.6	-8.6	7.1e-18	0.02	0.01	0.98	FALSE
94	The Cancer Genome Atlas	Prostate Adenocarcinoma	DOPEY1	0.07	0.11	blup	47	0.11	1.7e-11	7.1	-7.9	3.3e-15	0.01	0.93	0.07	FALSE
95	The Cancer Genome Atlas	Soft Tissue Sarcoma	DOPEY1	0.04	0.02	blup	47	0.02	1.4e-02	7.2	-8.5	2.0e-17	0.01	0.01	0.85	FALSE
96	The Cancer Genome Atlas	Soft Tissue Sarcoma	UBE2CBP	0.09	0.00	blup	85	0.03	6.4e-03	-5.4	6.7	1.6e-11	-0.01	0.06	0.15	FALSE
97	The Cancer Genome Atlas	Stomach Adenocarcinoma	DOPEY1	0.11	0.06	lasso	3	0.06	4.1e-05	8.6	-8.8	1.3e-18	0.01	0.01	0.99	FALSE
98	The Cancer Genome Atlas	Testicular Germ Cell Tumors	BCKDHB	0.19	0.02	blup	137	0.06	2.6e-03	11.1	8.9	6.0e-19	-0.13	0.03	0.05	FALSE