[Hub]/) : Traits : Height :

chr10:122,989,048-124,889,817

Best TWAS P=3.35e-53 · Best GWAS P=1.8e-43 conditioned to 0.322

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PLEKHA1 0.07 0.02 enet 18 0.06 2.0e-07 -1.9 7.6 2.2e-14 -0.19 0.12 0.85 FALSE
2 GTEx Adipose Subcutaneous PLEKHA1 0.14 0.06 lasso 2 0.03 2.4e-03 13.6 -13.6 2.9e-42 0.50 0.03 0.96 FALSE
3 GTEx Adipose Visceral Omentum RP11-500G22.2 0.29 0.00 enet 32 0.01 7.5e-02 -3.5 5.6 1.8e-08 -0.08 0.10 0.06 FALSE
4 GTEx Artery Tibial PLEKHA1 0.16 0.06 enet 18 0.08 1.3e-06 13.6 -8.9 4.8e-19 0.42 0.03 0.97 FALSE
5 GTEx Brain Nucleus accumbens basal ganglia RP11-500G22.2 0.73 0.36 lasso 20 0.27 5.8e-08 -3.5 5.5 3.4e-08 -0.06 0.90 0.01 FALSE
6 GTEx Brain Putamen basal ganglia RP11-500G22.2 0.40 0.16 enet 27 0.24 2.4e-06 -1.6 6.3 2.2e-10 -0.19 0.11 0.09 TRUE
7 GTEx Breast Mammary Tissue PLEKHA1 0.30 0.05 enet 38 0.01 8.6e-02 13.6 -7.7 1.1e-14 0.27 0.03 0.77 FALSE
8 GTEx Colon Sigmoid RP11-500G22.2 0.54 0.00 lasso 20 0.08 1.0e-03 3.1 6.2 4.2e-10 -0.11 0.18 0.05 FALSE
9 GTEx Esophagus Gastroesophageal Junction RP11-500G22.2 0.22 0.05 lasso 4 0.12 5.1e-05 -4.0 5.4 7.8e-08 -0.05 0.46 0.03 FALSE
10 GTEx Esophagus Mucosa RP11-500G22.2 0.23 0.03 lasso 10 0.02 1.4e-02 -3.5 5.7 1.1e-08 0.01 0.42 0.05 FALSE
11 GTEx Muscle Skeletal PLEKHA1 0.10 0.04 lasso 3 0.04 8.2e-05 -13.6 -12.5 7.7e-36 0.83 0.04 0.95 FALSE
12 GTEx Nerve Tibial PLEKHA1 0.22 0.23 enet 17 0.19 1.1e-13 13.6 -12.4 2.6e-35 0.41 0.03 0.97 FALSE
13 GTEx Pancreas PLEKHA1 0.29 0.05 lasso 11 0.07 4.7e-04 -8.3 -9.2 2.5e-20 0.77 0.06 0.78 FALSE
14 GTEx Pancreas TACC2 0.22 0.02 lasso 4 0.04 7.2e-03 -5.9 -6.6 3.1e-11 0.52 0.10 0.17 FALSE
15 GTEx Skin Sun Exposed Lower leg PLEKHA1 0.16 0.02 lasso 5 0.01 4.0e-02 -13.8 -14.2 8.6e-46 0.96 0.01 0.98 FALSE
16 METSIM Adipose PLEKHA1 0.05 0.03 lasso 4 0.04 3.6e-07 13.6 -15.4 3.3e-53 0.85 0.01 0.99 TRUE
17 ROSMAP Brain Pre-frontal Cortex PLEKHA1 0.06 0.05 lasso 4 0.05 1.3e-06 -13.6 -13.6 2.8e-42 0.65 0.07 0.93 FALSE
18 The Cancer Genome Atlas Brain Lower Grade Glioma PLEKHA1 0.04 0.05 lasso 2 0.04 4.3e-05 13.6 -13.5 9.8e-42 0.49 0.02 0.98 FALSE
19 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ARMS2 0.23 0.20 lasso 2 0.21 7.0e-09 -7.2 -8.0 9.0e-16 0.12 0.93 0.01 FALSE
20 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PLEKHA1 0.08 0.06 blup 103 0.02 4.0e-02 13.6 -12.3 8.7e-35 0.56 0.02 0.78 FALSE
21 The Cancer Genome Atlas Prostate Adenocarcinoma ARMS2 0.06 0.04 blup 71 0.05 4.9e-06 -13.6 -10.8 2.3e-27 0.28 0.02 0.97 FALSE
22 The Cancer Genome Atlas Thyroid Carcinoma PLEKHA1 0.08 0.10 lasso 1 0.09 3.5e-09 13.6 -13.6 7.4e-42 0.50 0.04 0.96 FALSE