Best TWAS P=3.24e-14 · Best GWAS P=2.82e-23 conditioned to 1.02e-21
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | FAM210B | 0.31 | 0.10 | enet | 11 | 0.11 | 1.6e-09 | 6.90 | -7.4 | 1.2e-13 | -0.02 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Artery Tibial | FAM210B | 0.19 | 0.10 | enet | 11 | 0.11 | 1.1e-08 | 6.72 | -7.6 | 3.2e-14 | -0.05 | 1.00 | 0.00 | TRUE |
| 3 | GTEx | Cells Transformed fibroblasts | FAM210B | 0.09 | 0.05 | lasso | 3 | 0.04 | 4.1e-04 | 6.75 | -6.9 | 4.1e-12 | 0.01 | 0.57 | 0.03 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | FAM210B | 0.11 | 0.06 | lasso | 2 | 0.03 | 1.2e-03 | 6.72 | -6.8 | 1.4e-11 | 0.02 | 0.65 | 0.10 | FALSE |
| 5 | METSIM | Adipose | FAM210B | 0.14 | 0.06 | enet | 15 | 0.14 | 8.2e-20 | 5.07 | -6.7 | 2.4e-11 | -0.14 | 1.00 | 0.00 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | AURKA | 0.04 | 0.03 | enet | 14 | 0.03 | 5.0e-04 | 6.19 | -6.0 | 2.2e-09 | 0.02 | 0.09 | 0.20 | FALSE |
| 7 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C20orf108 | 0.07 | 0.00 | blup | 54 | 0.01 | 4.1e-02 | -0.87 | -6.2 | 4.9e-10 | -0.17 | 0.01 | 0.05 | FALSE |
| 8 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | C20orf108 | 0.18 | 0.06 | blup | 56 | 0.09 | 1.5e-04 | 6.19 | -6.1 | 1.3e-09 | 0.05 | 0.04 | 0.16 | FALSE |