Best TWAS P=5.11e-14 · Best GWAS P=1.71e-27 conditioned to 8.41e-26
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | SLMO2 | 0.16 | 0.13 | lasso | 1 | 0.11 | 8.3e-09 | -6.6 | 6.6 | 3.1e-11 | 0.06 | 1.00 | 0.00 | TRUE |
| 2 | NTR | Blood | CTSZ | 0.02 | 0.00 | blup | 562 | 0.01 | 2.2e-03 | 7.7 | -7.5 | 7.8e-14 | -0.23 | 0.11 | 0.03 | FALSE |
| 3 | NTR | Blood | TH1L | 0.07 | 0.03 | bslmm | 553 | 0.05 | 4.8e-16 | 5.1 | -5.4 | 6.8e-08 | 0.04 | 1.00 | 0.00 | FALSE |
| 4 | YFS | Blood | CTSZ | 0.09 | 0.07 | bslmm | 517 | 0.09 | 4.5e-28 | 6.8 | 6.8 | 1.4e-11 | -0.06 | 1.00 | 0.00 | FALSE |
| 5 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | SLMO2 | 0.06 | 0.04 | blup | 51 | 0.03 | 8.8e-03 | -4.9 | 5.3 | 1.0e-07 | 0.04 | 0.04 | 0.22 | FALSE |
| 6 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLMO2 | 0.04 | 0.02 | blup | 51 | 0.02 | 1.6e-02 | 6.3 | 5.7 | 1.6e-08 | 0.06 | 0.02 | 0.33 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Adenocarcinoma | SLMO2 | 0.03 | 0.00 | blup | 52 | 0.01 | 3.0e-02 | -6.7 | 5.2 | 2.5e-07 | 0.02 | 0.08 | 0.06 | FALSE |
| 8 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | ZNF831 | 0.22 | 0.03 | enet | 6 | 0.15 | 9.0e-05 | 9.7 | -7.5 | 5.1e-14 | 0.00 | 0.02 | 0.62 | TRUE |