TWAS hub - YIF1A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Esophagus Muscularis	0.1090	0.0370	2.1e-05	0.049	NA	0.038	NA	0.010	5.9e-04	NA	2.4e-03	NA	7.7e-02
2	GTEx	Heart Atrial Appendage	0.0830	0.0400	6.6e-03	0.022	NA	0.013	NA	0.041	3.5e-02	NA	7.9e-02	NA	6.0e-03
3	GTEx	Muscle Skeletal	0.0987	0.0453	1.6e-03	-0.002	NA	0.008	NA	0.009	5.5e-01	NA	4.4e-02	NA	4.4e-02
4	GTEx	Pancreas	0.1540	0.0550	9.8e-05	0.179	NA	0.127	NA	0.170	5.0e-08	NA	5.1e-06	NA	1.2e-07
5	GTEx	Skin Sun Exposed Lower leg	0.0660	0.0280	2.1e-03	0.009	NA	0.000	NA	-0.002	5.3e-02	NA	2.9e-01	NA	4.9e-01
6	ROSMAP	Brain Pre-frontal Cortex	0.0315	0.0160	6.6e-03	0.006	0.012	0.001	0.012	0.005	4.5e-02	1.0e-02	2.2e-01	1.1e-02	7.0e-02
7	YFS	Blood	0.0240	0.0083	1.2e-07	0.038	0.029	0.034	0.033	0.034	1.7e-12	7.2e-10	2.1e-11	3.5e-11	1.8e-11
8	TCGA	Skin Cutaneous Melanoma	0.1880	0.0840	3.2e-03	-0.010	0.065	0.043	NA	0.019	7.7e-01	8.2e-03	2.7e-02	NA	1.0e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2011)	11.6	11.2	18.9	3.3	3.1	4.0	3.5	3.3	4.3	3.3	0.0
Bipolar Disorder (2018)	9.0	14.2	17.7	3.9	3.4	4.2	3.7	3.8	4.2	4.1	2.7
Chronotype (morning person)	8.0	18.6	27.7	-4.6	-4.3	-4.0	-4.7	-3.9	-5.3	-4.2	-3.2
Maternal smoking around birth	7.8	11.2	16.3	-4.0	-3.6	-1.7	-3.0	-2.7	-3.6	-3.7	-3.9
Handedness (chirality/laterality): Left-handed	5.8	7.0	10.9	3.1	3.0	1.9	3.0	1.9	2.1	3.3	2.5
Fed-up feelings	5.7	10.3	15.9	-3.8	-3.0	-1.3	-3.6	-1.7	-3.4	-4.0	-3.7
Bipolar Disorder or Schizophrenia	5.6	13.6	22.5	3.9	3.2	4.7	3.2	4.1	4.4	3.2	2.0
Schizophrenia vs Biploar Disorder	5.2	6.9	10.4	-2.8	-3.1	-2.0	-3.0	-2.0	-2.4	-3.2	-2.2
Triglycerides	5.2	8.5	14.9	-3.5	-3.2	-0.2	-3.7	-2.4	-3.3	-3.9	0.0
Long-standing illness, disability or infirmity	4.3	6.5	12.7	-3.6	-3.3	0.4	-2.7	-0.3	-1.1	-3.2	-3.1
Qualifications: A levels/AS levels or equivalent	4.2	9.2	18.3	4.3	3.9	0.5	3.2	1.4	2.7	3.8	2.5
Lung cancer (father)	3.8	4.4	7.1	-2.4	-2.7	-2.4	-2.2	-1.1	-1.6	-2.4	-1.7
Breast cancer (self-reported)	3.7	4.4	7.0	-2.1	-2.4	-2.4	-2.4	-0.7	-2.0	-1.6	-2.7
Supplements: Glucosamine	3.6	4.7	7.2	1.6	2.7	2.7	2.6	0.7	2.1	2.3	2.0
Overall health rating	3.4	7.2	16.5	-4.1	-3.3	1.6	-3.1	0.6	-0.1	-3.6	-2.2
Alcohol usually taken with meals	3.3	5.3	10.9	3.3	2.6	0.2	2.3	1.2	2.7	2.1	2.5
Medication: Allopurinol	3.1	4.2	10.7	-2.0	-1.6	-0.1	-1.9	-2.5	-3.3	-2.1	-1.3
Stomach or abdominal pain in last month	3.0	3.8	8.1	-2.8	-2.3	-0.7	-1.8	-1.3	-0.8	-2.2	-2.4
Diabetes diagnosed by doctor	3.0	5.0	8.7	-2.8	-2.1	1.5	-2.0	-1.0	-1.8	-2.9	-2.9
Number of operations (self-reported)	3.0	4.5	8.0	-2.8	-2.8	0.1	-1.7	-0.5	-2.3	-2.1	-2.8
Depressed Affect (Nagel 2018)	2.9	6.0	11.6	-2.9	-2.3	-0.0	-2.3	-2.1	-2.3	-3.4	-2.8
Breast Cancer	2.9	7.1	12.7	3.4	3.6	1.5	3.4	-0.8	1.9	2.9	2.4
Medication: Seretide 50 evohaler	2.9	3.3	7.5	-1.5	-1.6	-0.0	-2.0	0.4	-2.7	-1.8	-2.6
Mood swings	2.9	5.3	10.7	-3.0	-2.8	-0.1	-2.7	-1.3	-1.3	-3.3	-2.1
Supplements: Fish oil (including cod liver oil)	2.9	3.8	8.6	1.9	2.9	1.0	2.5	-0.5	1.9	2.1	1.8
Type 2 Diabetes (T2D) (2018)	2.8	5.2	9.5	-2.6	-2.1	1.7	-2.9	-0.8	-1.1	-3.1	-2.8
Had other major operations	2.8	3.4	8.4	-1.7	-2.0	-0.2	-1.8	-1.5	-1.9	-1.7	-2.9
Diabetes (self-reported)	2.8	4.4	7.8	-2.8	-2.1	1.0	-1.8	-1.0	-1.9	-2.6	-2.6
Number of self-reported non-cancer illnesses	2.8	4.9	13.0	-2.3	-1.8	2.5	-1.4	0.5	-1.8	-2.4	-3.6
Frequency of tiredness / lethargy in last 2 weeks	2.7	4.5	8.4	-2.6	-2.4	0.2	-2.2	-0.3	-1.6	-2.7	-2.9
Blood Eosinophil Count	2.6	19.9	59.9	-2.7	-1.7	3.1	-1.6	-5.3	-7.7	-3.3	-6.2
Qualifications: College or University degree	2.6	8.1	15.0	3.9	3.3	0.6	3.6	0.6	2.4	3.4	2.9
Pain experienced in last month	2.6	4.3	8.8	3.0	2.7	0.5	1.9	1.1	1.4	2.9	1.5
Medication: Levothyroxine sodium	2.4	4.0	5.3	-2.3	-2.2	-1.2	-1.8	-2.2	-2.3	-2.1	-1.7
Asthma	2.4	4.7	9.5	-2.2	-2.3	2.4	-2.1	-0.4	-1.3	-2.4	-3.1
Depression (self-reported)	2.4	2.9	7.2	1.3	1.9	2.7	1.9	1.9	1.0	1.3	0.8
Health satisfaction	2.4	3.1	5.8	-2.4	-2.2	0.6	-1.5	0.5	-1.1	-2.1	-2.4
Asthma (self-reported)	2.4	4.8	10.8	-2.2	-2.4	2.1	-2.1	-0.5	-1.4	-2.4	-3.3
Medication: Amlodipine	2.3	3.2	6.9	-1.6	-1.4	0.5	-1.8	-1.7	-1.0	-2.5	-2.6
Leg fat mass (right)	2.3	9.0	29.2	-5.4	-4.2	-0.3	-2.6	-1.0	-0.3	-4.1	-0.5
Illness, injury, bereavement, stress in last 2 years	2.3	2.8	4.8	1.9	2.2	0.2	2.0	0.5	1.9	2.1	1.1
Cholesterol lowering medication	2.3	3.3	5.9	-2.4	-2.0	0.0	-2.2	-0.6	-1.4	-2.4	-1.9
Hypothyroidism (self reported)	2.2	5.1	9.1	-2.9	-1.8	-0.4	-1.9	-2.3	-3.0	-2.6	-2.0
Heel bone mineral density (BMD) T-score, automated (right)	2.2	5.1	13.8	-1.3	-0.6	1.3	-1.8	-2.1	-3.4	-2.1	-3.7
Qualifications: None of the above	2.2	4.6	7.5	-2.4	-2.3	-0.1	-2.7	-0.3	-2.1	-2.7	-2.5
Mouth/teeth dental problems	2.2	3.3	10.0	-0.9	-1.4	-3.2	-1.5	-1.6	-2.4	-1.2	-1.2
Noisy workplace	2.2	2.7	6.3	-2.5	-2.0	-0.8	-1.6	0.1	-1.6	-1.5	-1.9
Whole body fat mass	2.2	9.4	30.5	-5.5	-4.2	-0.2	-2.6	-1.1	-0.8	-4.1	-1.1
Back pain experienced in last month	2.2	3.2	6.6	-2.4	-2.4	-0.3	-1.8	-1.3	-1.1	-2.6	-1.2
Mother’s age at death	2.2	2.7	3.5	1.9	1.6	0.1	1.9	1.7	1.8	1.6	1.9
Major Depression (MDD)	2.1	2.6	8.5	1.8	1.5	2.9	1.4	1.9	0.2	0.9	-0.5
Trunk fat mass	2.1	9.1	29.8	-5.5	-4.1	-0.5	-2.5	-1.2	-1.1	-3.9	-1.3
Waist circumference	2.1	7.7	19.7	-4.4	-3.5	1.3	-2.7	-1.1	-0.2	-4.2	-1.4
Arm fat mass (right)	2.1	8.6	28.2	-5.3	-4.1	0.5	-2.4	-0.6	-0.3	-3.8	-1.5
Hypothyroidism/myxoedema (self-reported)	2.0	3.9	6.1	-2.5	-1.6	-0.3	-1.8	-2.2	-2.4	-2.3	-1.8
Average weekly red wine intake	2.0	2.9	9.6	3.1	2.2	0.0	1.5	-0.1	2.0	1.7	-0.3
Mineral and other dietary supplements	2.0	2.7	5.8	-1.4	-2.4	-1.5	-2.1	0.1	-1.4	-1.8	-1.3
Arm fat mass (left)	2.0	8.2	27.5	-5.2	-4.0	0.2	-2.3	-0.7	-0.2	-3.7	-1.4
Leg fat mass (left)	2.0	7.9	26.5	-5.2	-3.9	-0.1	-2.4	-0.7	-0.0	-3.9	-0.3
Frequency of depressed mood in last 2 weeks	1.9	2.7	6.2	-1.9	-1.7	-0.8	-1.5	-0.7	-1.7	-1.6	-2.5
Weight	1.9	9.3	28.4	-5.3	-4.2	-0.7	-2.6	-1.9	-0.8	-4.0	-1.0
Father’s age at death	1.9	2.5	6.4	1.4	1.2	-0.6	2.5	0.5	1.1	1.8	2.3
Leg fat percentage (right)	1.9	6.8	21.9	-4.7	-3.4	0.4	-2.4	-0.6	-0.2	-3.9	-0.2
Waist Hip Ratio (WHR)	1.8	8.1	18.2	-2.2	-2.1	3.0	-3.0	-2.3	-1.7	-4.3	-3.2
Trunk fat percentage	1.8	7.1	25.1	-5.0	-3.6	-0.0	-2.1	-0.7	-1.0	-3.4	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.3	8.5	-1.4	-1.1	0.7	-1.3	-0.3	-1.5	-1.6	-2.9
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.0	11.3	-1.4	-0.7	1.2	-1.7	-1.8	-2.7	-1.8	-3.4
Hair/balding pattern: Pattern 3	1.8	2.8	5.0	1.4	1.6	0.7	1.7	1.9	2.2	1.5	1.7
Headache pain in last month	1.8	3.0	7.5	-1.7	-1.7	-1.3	-1.4	-1.5	-1.5	-1.7	-2.7
Gout (self-reported)	1.8	2.5	6.8	-1.4	-0.9	0.8	-1.5	-1.8	-2.6	-1.8	-1.1
Body fat percentage	1.8	7.3	25.7	-5.1	-3.7	0.3	-2.2	-0.5	-0.6	-3.6	-0.9
Medication: Bendroflumethiazide	1.8	2.7	6.2	0.8	1.1	1.9	1.1	1.6	2.3	0.6	2.5
BMI	1.7	9.8	32.3	-5.7	-4.5	-0.5	-2.4	-1.0	0.9	-4.2	-0.8
Body mass index (BMI)	1.7	7.3	24.3	-4.9	-3.7	0.6	-2.2	-0.3	1.0	-3.6	-0.9
Qualifications: O levels/GCSEs or equivalent	1.7	2.7	5.6	1.8	2.0	-0.1	2.1	0.8	1.1	2.4	1.6
Commuting to job workplace: Cycle	1.7	2.0	4.1	2.0	1.2	-1.8	0.8	-0.1	1.9	1.7	-0.0
Serious illness, injury or assault to yourself	1.6	2.0	3.5	-1.8	-1.9	0.8	-1.8	0.8	-0.6	-1.5	-1.4
Arm fat percentage (right)	1.6	6.5	22.0	-4.7	-3.7	1.0	-1.9	0.3	0.2	-3.1	-1.5
Shortness of breath walking on level ground	1.6	2.0	3.8	-1.6	-1.7	-1.7	-1.1	-0.1	-0.2	-1.6	-1.9
Arm fat percentage (left)	1.6	6.3	22.2	-4.7	-3.5	0.9	-1.9	0.0	0.2	-3.2	-1.3
Medication: Blood pressure	1.6	3.0	6.6	-1.5	-1.2	2.6	-1.9	-0.8	-1.1	-2.5	-1.5
Leg fat percentage (left)	1.6	6.0	20.2	-4.5	-3.1	0.5	-2.1	-0.3	0.1	-3.6	0.0
Schizophrenia (2018)	1.5	3.1	7.3	1.8	1.4	2.7	1.1	2.2	2.4	0.8	0.4
Heel T-Score	1.5	11.7	26.1	-1.6	-0.2	5.1	-2.1	-3.0	-5.1	-2.8	-4.2
Respiratory disease	1.5	3.3	11.6	-0.9	-1.0	3.4	-1.6	0.3	-0.9	-1.5	-2.6
Eye problems/disorders: Diabetes related eye disease	1.5	1.6	3.3	-1.7	-1.4	0.5	-1.4	-1.3	-0.1	-1.8	-0.9
Medication: Metformin	1.5	2.1	4.6	-2.0	-1.3	0.8	-1.1	-0.8	-0.9	-2.1	-1.7
Taking other prescription medications	1.5	2.3	6.9	-1.9	-1.3	1.1	-0.3	0.6	-1.0	-1.8	-2.6
Qualifications: CSEs or equivalent	1.5	2.0	3.5	-1.8	-1.3	-0.5	-1.7	-1.1	-1.9	-1.4	-1.0
Alcohol intake frequency.	1.5	3.4	9.4	-3.1	-3.0	0.5	-1.7	-0.5	-0.8	-2.3	-0.1
Had major operations	1.5	1.8	3.8	-1.9	-1.9	-0.5	-1.2	-1.3	-0.9	-1.5	-0.5
Friendships satisfaction	1.5	1.8	7.5	-0.7	-0.7	0.2	-0.6	-1.4	-1.6	-1.1	-2.7
Alzheimer’s Disease (in father)	1.4	1.5	3.6	-1.4	-0.8	-0.8	-1.1	-1.3	-1.9	-1.4	-0.9
Schizophrenia (2014)	1.4	3.2	9.7	1.2	1.1	3.1	1.1	2.2	2.3	0.8	1.0
Allergy or Eczema	1.4	3.6	21.5	1.5	1.6	4.6	0.3	0.1	-0.5	-0.0	-1.5
Blood clot in the leg (DVT)	1.4	1.8	4.4	-1.5	-1.5	0.2	-1.3	-0.2	-1.3	-1.6	-2.1
Age at last live birth	1.4	2.0	4.4	2.0	1.6	0.3	2.1	0.1	0.6	1.8	1.2
Commuting to job workplace: Public transport	1.4	1.7	3.0	1.5	0.8	1.7	1.6	0.8	1.2	1.4	1.2
Arm fat-free mass (left)	1.4	7.0	16.8	-4.1	-3.6	-1.6	-2.4	-2.1	-1.0	-3.4	-0.9
Ever depressed for a whole week	1.4	1.7	5.2	1.3	1.3	0.4	1.1	2.3	1.3	1.1	0.9
Arm predicted mass (left)	1.4	7.2	16.6	-4.1	-3.7	-1.5	-2.6	-2.0	-1.1	-3.5	-1.0
Allergy	1.3	3.0	14.4	0.5	0.8	-3.8	1.2	-0.1	0.8	1.3	2.2
Hip circumference	1.3	5.7	18.7	-4.3	-3.4	-1.3	-1.9	-1.6	-0.4	-2.7	-0.5
Chronic bronchitis/emphysema (mother)	1.3	1.5	2.7	-1.2	-1.4	-1.4	-1.3	0.2	-1.2	-0.7	-1.6
Arm fat-free mass (right)	1.3	6.8	15.8	-4.0	-3.5	-1.7	-2.4	-2.2	-0.9	-3.4	-0.6
Pulse rate, automated reading	1.3	4.0	8.1	-2.8	-2.2	-1.3	-1.5	-1.2	-2.3	-1.9	-2.2
Basal metabolic rate	1.3	7.0	17.2	-4.2	-3.7	-1.6	-2.4	-2.2	-0.7	-3.3	-0.9
Average weekly beer plus cider intake	1.3	1.8	3.9	-1.5	-1.6	0.4	-1.8	-0.1	-0.8	-1.4	-2.0
Height	1.2	22.5	51.3	-3.8	-3.0	-6.1	-2.8	-7.2	-6.9	-3.4	-1.1
Cardiovascular Disease	1.2	3.9	17.9	-1.9	-0.9	4.2	-0.9	0.2	0.2	-1.8	-2.2
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	2.8	-1.6	-1.7	0.8	-1.3	-0.4	-0.1	-1.6	-1.3
Systolic blood pressure, automated reading	1.2	3.5	10.4	1.7	2.1	3.2	0.6	2.0	2.1	0.7	1.1
Severe depression (siblings)	1.2	1.4	3.9	1.2	1.6	1.0	2.0	0.4	0.7	1.0	0.7
Leg fat-free mass (left)	1.2	6.2	16.0	-4.0	-3.7	-1.5	-2.3	-1.7	-0.2	-2.9	-1.0
Leg predicted mass (left)	1.2	6.2	15.9	-4.0	-3.7	-1.6	-2.3	-1.7	-0.3	-2.9	-1.0
Medication: Simvastatin	1.2	1.8	10.0	-0.6	-0.1	3.2	0.3	1.0	-0.7	-0.4	-1.5
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	2.9	1.1	1.2	0.4	1.7	0.5	1.7	1.7	0.7
Glaucoma (self-reported)	1.2	1.5	4.9	0.1	0.2	0.0	-0.3	-1.2	-2.2	-0.9	-2.1
Arm predicted mass (right)	1.2	6.1	14.1	-3.8	-3.3	-1.9	-2.2	-2.2	-0.7	-3.2	-0.4
Medication for cholesterol	1.2	1.8	3.8	1.0	1.0	-1.4	1.8	0.1	1.1	1.9	1.6
Guilty feelings	1.2	1.8	6.0	-1.3	-0.2	0.4	0.6	-1.0	-2.3	-0.4	-2.4
Depression (Nagel 2018)	1.1	1.6	6.6	-1.1	-1.0	0.1	-1.0	-0.9	-0.9	-1.2	-2.6
Primary Biliary Cirrhosis	1.1	1.6	3.5	-0.9	-1.4	0.4	-1.9	-0.1	-1.4	-1.7	-1.3
Number of treatments/medications taken	1.1	2.0	10.5	-0.6	-0.3	3.2	0.4	1.5	0.9	-0.6	-1.3
Hearing difficulty/problems: Yes	1.1	1.7	4.2	1.1	1.2	1.2	2.0	0.7	1.7	1.4	0.5
Average weekly fortified wine intake	1.1	1.3	2.8	0.9	0.8	-0.3	1.4	1.7	1.2	1.5	0.1
Relative age voice broke	1.1	1.7	3.7	1.6	0.6	-0.1	0.9	1.4	1.9	1.6	1.3
Hearing difficulty/problems with background noise	1.1	1.7	4.5	0.8	1.4	2.1	1.4	1.1	0.6	0.9	-1.6
High blood pressure (siblings)	1.1	1.6	5.3	-0.1	1.0	1.7	0.4	0.8	2.3	0.4	1.7
Whole body fat-free mass	1.1	6.2	13.5	-3.7	-3.4	-1.9	-2.2	-2.3	-0.7	-3.0	-0.8
Whole body water mass	1.1	6.1	13.5	-3.7	-3.4	-1.9	-2.2	-2.2	-0.7	-3.0	-0.9
Miserableness	1.1	1.9	4.2	-1.7	-1.2	-0.4	-1.3	-1.0	-1.1	-2.0	-1.6
Blood Platelet Count	1.0	12.2	37.3	-1.9	-2.3	-6.1	-0.6	-4.5	-3.8	-0.7	-4.0
Hand grip strength (left)	1.0	2.7	7.1	-0.9	-1.0	-2.4	-1.6	-2.7	-1.8	-1.0	0.1
Pack years adult smoking proportion	1.0	1.5	3.2	-1.4	-1.8	-0.8	-1.6	0.5	-0.5	-1.8	-0.3
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	3.8	0.9	0.6	0.7	0.2	1.4	1.9	0.7	0.9
Hayfever, allergic rhinitis or eczema	1.0	2.1	11.0	0.2	-0.0	3.3	-0.8	-0.4	-1.4	-0.9	-1.4
Trunk predicted mass	1.0	5.5	9.9	-3.1	-3.0	-2.0	-2.0	-2.6	-1.1	-2.9	-0.8
Tense / ‘highly strung’	1.0	1.7	5.3	1.1	1.1	2.3	1.1	0.5	1.6	1.1	0.6
Pulse wave reflection index	1.0	1.2	2.5	1.2	1.3	0.8	1.3	0.2	0.7	1.1	1.6
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	2.8	0.8	0.6	0.1	1.2	0.2	1.7	1.5	1.4
Leg fat-free mass (right)	1.0	5.1	13.8	-3.7	-3.4	-1.5	-2.0	-1.6	0.1	-2.5	-0.8
High cholesterol (Self-reported)	1.0	1.7	5.5	-1.5	-1.3	0.8	-1.0	0.5	-0.7	-1.2	-2.3
Supplements: Calcium	1.0	1.1	3.8	1.1	1.2	0.6	1.9	-0.4	0.6	1.1	0.4
Relative age of first facial hair	0.9	1.8	4.1	1.0	-0.2	-2.0	0.6	1.5	2.0	1.5	0.2
Hand grip strength (right)	0.9	2.5	4.8	-1.7	-1.5	-1.5	-1.8	-2.2	-1.7	-1.3	0.2
Sitting height	0.9	6.6	10.6	-2.8	-2.4	-2.4	-2.6	-3.2	-2.7	-2.6	-1.4
Medication: Ramipril	0.9	1.2	2.9	-1.4	-1.1	0.2	-1.3	-0.3	-0.2	-1.7	-1.2
Trunk fat-free mass	0.9	5.4	9.7	-3.1	-2.9	-2.0	-2.0	-2.5	-1.1	-2.9	-0.8
Wheeze or whistling in the chest in last year	0.9	1.5	3.2	-1.3	-1.6	1.8	-1.3	-0.1	-0.0	-1.4	-1.2
Mean time to correctly identify matches	0.9	1.6	8.4	0.7	0.6	0.2	0.3	2.9	-1.1	0.3	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	1.5	1.2	1.2	1.2	1.1	0.3	1.1	1.1	1.0
Suffer from ‘nerves’	0.9	1.4	3.4	1.9	1.3	1.0	1.1	0.3	0.8	1.7	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	2.3	0.4	0.6	1.2	-0.3	1.5	1.5	0.8	1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	5.4	-0.8	-1.0	-0.9	-1.4	-0.3	-2.3	-1.0	-1.9
Commuting to job workplace: Walk	0.9	1.0	2.0	1.3	1.0	0.7	1.0	0.8	0.8	1.4	0.5
Osteoporosis (self-reported)	0.9	1.1	2.7	-0.9	-1.1	-0.8	-1.1	-0.3	-0.9	-1.2	-1.7
Leg predicted mass (right)	0.9	5.0	13.8	-3.7	-3.4	-1.5	-1.9	-1.6	0.1	-2.5	-0.8
Eye problems/disorders: Glaucoma	0.9	1.1	3.4	0.4	0.3	0.8	0.0	-0.8	-1.8	-0.8	-1.7
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	3.8	-1.0	-1.0	0.2	-0.9	0.1	-1.1	-1.2	-1.9
Reaction Time	0.8	1.6	6.7	1.1	0.9	1.3	0.2	2.6	-0.6	0.3	-1.5
Age at First Birth	0.8	1.1	3.3	1.5	1.2	-0.0	0.6	1.8	-0.5	1.1	0.0
HbA1C	0.8	0.9	2.4	-1.5	-1.1	-0.5	-0.7	-0.7	-1.1	-0.6	-1.1
HDL Cholesterol	0.8	1.4	4.2	1.1	0.8	-2.1	1.5	0.5	-0.4	1.5	0.0
Ulcerative Colitis	0.8	1.2	3.6	0.1	-0.6	1.9	1.0	1.5	1.1	1.0	-0.6
Average weekly spirits intake	0.8	1.0	3.3	-1.8	-1.2	-1.2	-0.7	-0.4	-0.1	-0.9	-0.5
Ever had hysterectomy (womb removed)	0.8	0.9	2.8	-0.8	-1.5	-1.7	-1.1	0.0	-0.1	-0.6	-0.6
Diabetes (father)	0.8	1.0	2.0	-1.4	-0.7	1.0	-0.9	-0.4	-0.8	-1.3	-1.3
Medication: Cholesterol lowering	0.8	1.3	7.5	0.1	0.2	2.7	0.4	1.3	-0.0	0.1	-1.1
Hair/balding pattern: Pattern 4	0.8	1.8	3.3	1.4	1.6	-0.5	1.8	0.6	0.6	1.6	1.8
Ever highly irritable/argumentative for 2 days	0.8	1.0	1.6	0.9	1.1	1.2	1.0	0.5	0.9	1.0	1.3
Worry too long after embarrassment	0.8	1.3	4.7	-0.9	-0.6	-1.1	-1.0	0.1	-1.1	-1.1	-2.2
Age at first live birth	0.8	1.4	3.4	1.4	1.3	-0.7	1.8	-0.3	0.1	1.3	1.4
Migraine (self-reported)	0.8	0.9	4.5	-0.6	-0.9	-0.4	-0.5	-0.9	-0.5	-0.7	-2.1
Number of full sisters	0.8	1.0	5.3	0.4	0.3	2.3	0.5	0.8	1.1	0.2	0.1
Illnesses of siblings: Diabetes	0.8	0.9	2.7	-1.1	-0.9	0.7	-1.1	-0.7	-0.8	-1.6	0.0
Qualifications: nursing, teaching	0.8	1.2	2.3	1.5	1.4	-1.2	1.5	-1.2	-0.6	0.2	0.3
Ever smoked	0.8	1.4	4.0	1.1	1.3	2.0	0.4	0.2	1.7	0.8	0.3
Neuroticism (Nagel 2018)	0.7	1.7	4.1	-1.5	-1.0	1.1	-0.5	-1.2	-1.0	-1.6	-2.0
Ulcerative Colitis (UC)	0.7	1.4	5.5	0.3	-0.4	2.3	0.9	1.3	1.2	1.1	-0.1
Verbal and Numeric Reasoning (VNR)	0.7	1.6	6.5	-0.9	-1.2	-2.6	-0.8	-1.3	-0.6	-0.7	-0.8
Prostate Cancer	0.7	1.0	1.8	1.0	1.1	-0.7	1.0	0.9	1.3	1.3	-0.0
Sensitivity / hurt feelings	0.7	1.3	3.1	-1.8	-1.2	-0.5	-0.6	-1.2	-0.9	-1.4	-0.9
Angina	0.7	1.0	2.1	-0.7	-1.0	-0.3	-1.5	-1.1	-0.5	-0.8	-1.4
High blood pressure	0.7	2.0	12.2	-1.0	0.0	3.5	0.2	0.8	0.4	-1.0	-0.9
Alcohol intake versus 10 years previously	0.7	1.0	3.9	-1.2	-0.9	2.0	-0.6	-0.2	0.0	-1.0	0.9
Mouth/teeth dental problems: Dentures	0.7	1.2	3.6	-0.1	0.7	1.6	0.6	0.1	1.7	-0.3	1.9
Prospective memory result	0.7	0.9	2.2	-1.5	-1.3	-0.2	-0.9	-1.1	-0.5	-1.0	0.3
Standing height	0.7	6.9	18.7	-1.8	-1.7	-3.2	-1.5	-3.8	-4.3	-1.8	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	4.0	-0.2	-0.1	1.1	0.4	1.7	2.0	0.2	0.0
Birth weight of first child	0.7	1.2	5.3	-0.4	-1.1	-2.3	-0.6	-1.5	-0.5	-0.2	-0.2
Peak expiratory flow (PEF)	0.7	1.6	5.0	1.5	1.2	0.5	1.1	-0.8	0.8	1.0	2.2
Loud music exposure frequency	0.7	0.7	2.1	-1.5	-0.9	0.3	-0.7	-0.4	-1.2	-0.7	-0.5
Number of children fathered	0.7	0.8	1.7	-0.9	-0.7	0.3	-1.0	-0.8	0.5	-1.1	1.3
Angina (self-reported)	0.7	1.0	2.4	-0.8	-1.1	-0.4	-1.5	-1.0	-0.3	-0.8	-1.3
Chest pain or discomfort	0.7	0.9	2.1	-0.8	-0.1	1.4	-1.0	-0.6	-0.1	-1.4	-1.2
Hypertension (Self-reported)	0.7	2.1	11.0	-1.4	-0.3	3.3	-0.2	0.5	0.1	-1.2	-1.3
Smoking status: Previous	0.7	1.0	6.1	0.3	0.8	2.5	0.1	-0.3	1.1	0.2	-0.6
Medication: Gliclazide	0.7	0.8	2.4	0.4	0.5	1.5	1.1	0.8	0.5	0.8	-1.0
Medication: Atorvastatin	0.7	0.8	2.2	-0.5	-0.8	0.3	-1.2	-0.2	-1.0	-0.9	-1.5
Irritability	0.7	1.1	3.5	-0.2	0.5	1.3	0.7	-1.0	1.4	0.0	1.9
Vascular/heart problems diagnosed by doctor	0.7	2.0	12.7	0.6	-0.1	-3.6	-0.1	-0.9	-0.9	0.7	0.8
Neuroticism (2016)	0.6	0.9	2.2	-1.2	-0.6	0.7	-0.1	-0.7	-1.1	-0.9	-1.5
Systolic Blood Pressure	0.6	3.0	17.6	0.9	1.2	4.2	-1.0	1.3	1.1	-0.8	0.1
Smoking Status	0.6	1.4	2.7	-1.4	-0.8	1.5	-1.6	-0.5	0.9	-1.3	-0.8
Lung FVC	0.6	3.1	7.5	2.7	1.9	1.9	1.2	-1.3	2.0	0.6	1.7
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	2.5	0.3	0.4	1.3	0.5	1.6	0.8	0.5	0.2
Happiness	0.6	0.8	1.6	-1.3	-0.7	0.5	-0.8	-0.9	-0.4	-1.2	-0.9
Medication: Ibuprofen	0.6	0.7	1.8	0.5	0.7	0.1	1.2	0.5	1.3	1.2	0.3
Average weekly champagne plus white wine intake	0.6	0.8	2.6	0.7	1.1	-1.0	0.9	-0.7	0.1	0.1	1.6
Diastolic blood pressure, automated reading	0.6	1.9	10.7	0.7	0.8	3.3	-0.9	0.8	1.1	-0.4	0.6
Unable to work because of sickness or disability	0.6	0.8	3.1	0.1	-0.8	-0.4	-0.6	1.8	-0.8	0.1	-1.3
Basal cell carcinoma (self-reported)	0.6	0.7	2.6	-0.3	-0.7	-1.6	-0.5	1.2	-0.4	0.1	-0.8
Pack years of smoking	0.6	0.9	1.9	-0.9	-1.4	-0.6	-1.1	0.9	-0.1	-1.4	0.2
Alzheimer’s Disease (including proxy)	0.5	0.7	1.6	-0.3	-0.4	-0.6	-0.7	-1.0	-1.3	-0.9	-0.8
Coronary Artery Disease (CAD)	0.5	0.6	1.8	-0.3	-0.7	1.3	-0.5	-0.3	-0.8	-1.1	0.0
Mean Putamen Volume	0.5	0.6	1.7	-1.3	-0.7	-0.4	-1.0	-0.4	-0.6	-0.7	-0.6
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.2	-1.1	-0.6	1.0	-0.9	0.6	0.5	-0.9	0.0
Vitamin and mineral supplements	0.5	0.7	2.5	0.0	-0.5	-1.6	-0.8	0.2	-1.1	-0.4	-0.8
Medication: Co-codamol	0.5	0.6	1.8	-0.1	-0.5	1.4	0.8	1.2	0.5	0.3	-0.2
Impedance of leg (right)	0.5	2.6	15.1	1.1	1.4	-0.1	-0.2	-1.6	-3.9	-0.1	0.1
High blood pressure (mother)	0.5	0.7	4.1	-0.6	0.4	2.0	0.0	-0.5	0.7	-0.2	0.4
Impedance of leg (left)	0.5	2.2	9.3	1.5	1.9	0.2	0.5	-1.0	-3.1	0.5	0.9
Past tobacco smoking	0.5	0.9	4.6	-0.1	-0.6	-2.1	-0.1	0.6	-1.1	0.0	0.7
Neuroticism score	0.5	1.1	1.8	-1.3	-1.0	-0.0	-0.6	-1.0	-1.0	-1.3	-1.3
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	5.0	1.7	1.1	-0.4	0.6	-1.6	0.4	0.9	2.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	3.8	1.8	1.2	-0.2	1.0	-1.3	0.3	1.1	1.9
Length of working week for main job	0.5	0.5	1.3	-1.2	-0.9	-0.4	-1.0	-0.2	-0.1	-0.2	-1.0
Breastfed as a baby	0.5	0.6	1.7	1.2	0.2	0.1	0.6	-0.3	-0.9	0.5	-1.3
Medication: Paracetamol	0.5	0.9	3.8	-1.0	-0.7	-0.2	0.1	-1.9	-0.7	-0.2	-1.1
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	4.0	0.5	-0.1	-2.0	-0.4	-0.9	-0.3	0.4	1.0
Exposure to tobacco smoke outside home	0.5	0.7	1.7	-1.0	-0.5	1.3	-0.9	-0.2	-0.9	-0.9	-0.3
Medication: Blood pressure	0.5	0.9	5.0	-0.1	0.7	2.2	1.0	0.3	0.5	0.2	-0.6
Heart disease (mother)	0.5	0.7	1.6	-0.7	0.4	0.3	-0.7	-1.3	-0.8	-1.0	-0.8
Comparative height size at age 10	0.5	3.0	7.8	-1.3	-1.0	-2.3	-0.3	-2.5	-2.8	-0.8	-1.0
Leg pain on walking	0.5	0.6	1.9	-0.7	-0.2	1.4	-0.2	-0.4	-0.5	-1.4	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.8	0.8	0.9	1.4	1.0	0.1	-0.2	1.3	0.7
Osteoarthritis (self-reported)	0.5	0.6	2.9	0.5	0.6	1.7	0.1	1.0	-0.0	0.2	0.3
Smoking status: Current	0.5	0.9	2.3	-0.8	-1.1	-0.0	-1.5	1.1	0.2	-1.0	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	2.5	1.6	0.9	-0.4	1.1	0.2	1.3	0.9	1.2
Financial situation satisfaction	0.5	0.6	2.0	-0.4	-0.3	0.2	-0.7	0.6	-1.2	-0.5	-1.4
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.2	-0.5	0.2	0.5	1.1	0.5	0.6	0.0	1.5
Medication: Lisinopril	0.5	0.7	2.7	0.4	1.1	1.6	0.7	0.4	0.5	0.5	0.1
Medication: Omeprazole (e.g. Zanprol)	0.5	0.7	2.9	0.1	-0.1	0.7	0.6	0.8	1.7	0.0	1.0
Intelligence (Savage-Jansen 2018)	0.4	1.2	6.0	0.6	0.2	-2.4	0.4	-1.2	-1.1	0.4	-0.8
Worry (Nagel 2018)	0.4	0.8	1.5	0.8	0.7	1.2	1.2	-0.2	0.9	1.1	0.6
Irritable Bowel Disease (IBD)	0.4	0.8	2.3	-0.1	-0.6	1.5	0.6	1.2	1.2	0.7	-0.6
LDL Cholesterol	0.4	0.7	1.5	-1.2	-1.2	-0.5	-0.8	1.0	0.5	-0.5	0.0
Blood Red Count	0.4	4.2	17.4	-0.0	0.4	3.2	0.2	1.4	4.2	-0.8	1.8
Townsend deprivation index at recruitment	0.4	0.5	1.9	-1.0	-0.5	0.8	-0.6	-0.3	-0.2	-1.4	-0.0
Current tobacco smoking	0.4	0.7	2.5	-0.4	-0.7	0.5	-1.2	1.6	0.6	-0.6	-0.1
Financial difficulties in last 2 years	0.4	0.5	1.4	-0.7	-0.7	0.3	-1.2	0.2	0.0	-1.1	-0.4
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	3.1	0.7	0.1	1.8	-0.6	0.1	-0.3	-0.2	0.3
Impedance of arm (right)	0.4	1.6	7.5	1.3	1.0	0.1	0.5	-0.4	-2.7	1.1	-1.1
Worrier / anxious feelings	0.4	0.7	1.2	-0.9	-1.1	-1.0	-0.3	-0.4	-0.8	-0.8	-1.0
Impedance of arm (left)	0.4	1.8	8.5	1.1	1.1	-0.4	0.4	-0.8	-2.9	1.0	-1.0
Medication: Ventolin 100micrograms inhaler	0.4	0.5	2.7	0.6	0.1	1.6	0.1	0.8	0.1	0.1	-0.1
Eye problems/disorders: None of the above	0.4	0.5	1.9	0.4	0.1	-0.1	0.3	1.4	0.3	1.2	0.2
Mouth/teeth dental problems: Loose teeth	0.4	0.4	1.9	-0.1	0.0	0.3	-0.3	-1.4	0.1	-1.1	-0.0
Medication: Omeprazole	0.4	0.5	1.5	-0.3	-0.7	0.8	0.2	0.8	1.2	-0.3	0.6
Family relationship satisfaction	0.4	0.5	1.6	0.9	0.9	0.4	-0.0	0.8	-0.2	0.5	-1.3
Supplements: Vitamin C	0.4	0.4	1.3	0.7	0.7	0.1	0.7	0.4	0.4	0.6	1.1
Wears glasses or contact lenses	0.4	0.4	1.0	-0.7	-0.6	-0.7	0.1	0.5	0.8	-0.2	1.0
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.7	0.3	-0.2	-1.3	0.1	1.1	0.6	0.5	0.3
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.2	-0.6	-1.1	-0.9	-0.4	0.7	-0.2	-0.2	-0.9
Age started oral contraceptive pill	0.4	0.5	2.5	0.1	-0.3	-1.6	-0.3	0.7	0.5	0.1	0.4
Heart disease (siblings)	0.4	0.4	2.1	0.1	-0.1	0.6	-0.1	1.5	-0.2	0.4	-0.9
Alcohol drinker status: Previous	0.4	0.4	1.4	-1.0	-1.2	0.7	0.1	-0.5	0.1	-0.4	-0.3
Impedance of whole body	0.4	2.0	11.7	1.1	1.3	-0.2	0.3	-0.9	-3.4	0.7	-0.5
Alzheimer’s Disease (in mother)	0.3	0.3	0.8	0.9	0.8	-0.0	0.8	-0.4	0.1	0.5	0.3
Body Mass Index (BMI) (2010)	0.3	0.4	1.4	-0.7	-0.4	1.2	-0.6	0.0	0.5	-0.6	0.0
Rheumatoid Arthritis	0.3	0.4	0.7	-0.5	-0.6	0.7	-0.6	-0.7	-0.9	-0.5	-0.3
Lung FEV1/FVC ratio	0.3	1.4	5.2	-0.5	-0.0	-2.1	-0.3	0.8	0.5	-0.0	2.3
Hair Pigment	0.3	8.6	50.1	1.1	0.2	-7.1	1.7	-0.7	2.1	2.9	1.0
Diabetes (mother)	0.3	0.4	1.5	-0.7	0.0	0.8	-0.0	-0.1	0.1	-1.2	-0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.7	-0.4	-0.8	0.5	-0.6	0.8	-0.0	-0.7	0.0
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.9	0.3	0.8	-0.9	0.5	-0.3	0.4	0.0	-0.4
Number of incorrect matches in round	0.3	0.5	2.0	-0.3	-0.7	-1.4	0.1	-0.9	0.0	0.5	0.8
Hair/balding pattern: Pattern 2	0.3	0.4	1.6	0.1	-0.7	-1.3	-0.4	-0.2	-0.7	-0.2	-0.6
Forced vital capacity (FVC)	0.3	1.3	7.3	0.8	0.3	-0.5	-0.1	-2.7	-0.8	-0.1	1.2
Pain all over the body in last month	0.3	0.4	0.9	-0.4	-0.6	0.4	-0.3	0.9	-0.6	-0.8	-0.5
Illnesses of siblings	0.3	0.4	1.2	0.8	0.1	-1.1	0.4	-0.8	-0.8	0.4	-0.3
Pulse wave Arterial Stiffness index	0.3	0.4	0.8	-0.9	-0.5	0.7	0.4	-0.6	0.1	-0.9	0.7
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.4	-0.3	-0.0	0.8	-0.1	1.0	1.2	-0.0	-0.4
Birth weight	0.3	0.7	2.2	-0.3	-0.9	-0.1	0.1	1.2	1.5	1.0	-0.4
Forced vital capacity (FVC), Best measure	0.3	1.1	4.8	1.1	0.6	0.1	0.4	-2.2	-1.1	0.1	0.8
Comparative body size at age 10	0.3	0.9	4.2	-0.4	-0.5	-0.9	0.3	2.0	1.2	0.7	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.6	0.1	0.2	0.8	0.4	0.3	1.3	0.5	0.0
Pulse wave peak to peak time	0.3	0.3	0.9	0.6	0.3	-1.0	-0.5	0.1	-0.4	0.6	-0.7
Knee pain experienced in last month	0.3	0.5	1.2	-1.0	-1.0	0.6	-0.7	0.1	-0.0	-1.1	0.4
Loneliness, isolation	0.3	0.4	1.1	-0.5	-0.2	0.7	-0.0	-0.6	-0.8	-1.0	-0.6
Eye problems/disorders: Cataract	0.3	0.4	0.9	0.7	0.7	-0.4	0.1	-0.1	0.9	-0.0	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.8	-0.4	-0.8	0.3	-0.5	-0.9	-0.2	-0.5	-0.7
Illnesses of father: None of the above (group 1)	0.3	0.3	1.4	-0.3	-0.4	-1.2	-0.4	0.2	-0.8	-0.1	0.0
Risk taking	0.3	0.4	1.7	0.1	-0.4	-0.1	-1.3	-0.5	0.2	-0.7	-0.9
Myopia	0.3	0.5	2.7	0.4	0.1	-1.6	-0.2	-0.8	0.2	-0.1	-0.3
Crohns Disease (2012)	0.2	0.3	1.1	-0.3	-0.3	0.3	0.4	0.2	0.6	-0.2	-1.0
Blood White Count	0.2	1.8	5.0	-0.9	-0.6	1.6	-0.4	-2.2	-1.1	-1.3	-1.6
Neuroticism	0.2	0.6	1.2	-1.0	-0.7	0.8	-0.3	-0.5	-0.5	-0.9	-1.1
Tanning	0.2	2.8	4.9	-1.8	-2.2	-0.2	-1.8	-0.7	-2.1	-1.7	-1.8
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.5	0.2	-0.5	0.4	0.0	1.2	-0.1	-0.1	-0.1
Medication for hormone replacement therapy	0.2	0.3	1.3	0.2	-0.5	-1.1	-0.6	0.4	0.2	-0.1	-0.2
Supplements: Zinc	0.2	0.2	0.5	0.3	0.3	0.3	0.4	0.6	0.7	0.6	0.2
Age when periods started (menarche)	0.2	0.4	0.8	-0.0	0.4	-0.9	0.8	-0.5	-0.5	0.8	0.8
Medication: Atenolol	0.2	0.2	0.5	-0.1	0.1	0.4	0.5	-0.7	-0.5	-0.0	-0.7
Fluid intelligence score	0.2	0.5	2.1	0.3	0.2	-1.5	0.3	-1.0	0.3	0.4	0.6
Number of live births	0.2	0.2	0.8	0.4	0.0	0.4	0.5	0.9	-0.3	-0.0	-0.5
Pulse rate	0.2	0.3	0.7	0.1	-0.2	0.8	0.5	0.7	0.4	0.8	-0.6
Medication: Lansoprazole	0.2	0.2	0.7	0.4	0.6	0.2	0.2	0.8	0.5	0.1	-0.3
Illnesses of mother	0.2	0.3	0.5	0.7	-0.2	-0.7	0.4	-0.5	-0.1	0.6	0.6
Number of full brothers	0.2	0.2	0.9	0.3	0.6	0.4	0.4	-0.9	0.0	-0.3	-0.1
Medication for pain relief, constipation, heartburn	0.2	0.4	1.5	0.4	0.0	-1.2	-0.7	0.1	-0.7	0.2	0.6
Neck or shoulder pain in last month	0.2	0.3	1.1	-0.8	-0.4	1.0	-0.4	0.3	0.4	-0.3	0.5
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.6	-0.0	0.2	-0.5	0.4	-0.0	0.6	-0.0	0.8
Medication: Aspirin	0.2	0.3	0.6	-0.5	0.3	0.8	-0.1	-0.7	-0.2	-0.6	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	1.2	-0.1	-0.1	-1.1	0.4	0.3	0.6	0.1	-0.0
Medication: Aspirin	0.2	0.3	1.0	-0.3	0.6	1.0	0.2	-0.6	-0.3	-0.3	-0.5
Hearing aid user	0.2	0.2	1.0	-0.1	0.4	-0.2	1.0	-0.1	-0.3	0.6	-0.2
Medication: Paracetamol	0.2	0.3	0.9	-0.8	-0.5	-0.0	0.4	-0.8	-0.3	0.1	-0.9
Alcohol drinker status: Never	0.2	0.3	1.6	-0.0	-0.1	-1.3	0.3	0.4	-0.0	0.5	-0.3
Heart attack/myocardial infarction (self-reported)	0.2	0.3	1.2	-0.3	-0.5	0.3	-0.5	-0.6	-0.3	-0.1	-1.1
Crohns Disease (2017)	0.1	0.3	1.1	-0.6	-0.7	0.1	-0.1	0.3	0.5	-0.2	-1.1
Ovarian Cancer	0.1	0.1	0.6	-0.1	-0.1	-0.0	0.0	0.2	-0.2	0.1	-0.8
Fasting Glucose	0.1	0.1	0.5	-0.1	0.3	0.5	0.1	-0.7	-0.0	-0.5	-0.3
Lupus	0.1	0.1	0.7	0.0	0.4	0.8	0.1	-0.1	-0.2	-0.3	0.0
Multivitamins +/- minerals	0.1	0.2	0.7	-0.3	0.4	0.8	0.2	-0.4	0.4	0.2	0.2
Chronic bronchitis/emphysema (father)	0.1	0.1	0.5	0.1	0.1	-0.7	0.4	-0.4	-0.0	0.0	-0.4
Nervous feelings	0.1	0.2	1.0	-0.1	-0.2	-0.2	0.2	-0.7	-1.0	0.0	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.6	-0.5	-0.0	0.1	0.1	0.8	0.4	0.1	-0.6
Had menopause	0.1	0.1	0.4	0.1	-0.0	-0.4	0.6	0.3	-0.6	0.3	-0.3
Heart attack	0.1	0.1	0.5	0.0	-0.1	0.6	-0.2	-0.3	-0.2	0.2	-0.7
Time employed in main current job	0.1	0.1	0.2	-0.1	0.2	-0.4	0.3	0.4	-0.1	0.4	-0.4
Falls in the last year	0.1	0.1	0.4	-0.0	-0.0	0.4	-0.1	0.4	0.2	-0.6	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.4	0.6	0.3	0.0	0.1	-0.3	-0.0	0.2	0.4
Exposure to tobacco smoke at home	0.1	0.1	0.6	0.2	-0.0	0.5	-0.3	0.8	0.0	-0.1	0.1
Emphysema/chronic bronchitis	0.1	0.2	0.5	0.4	0.4	0.0	-0.1	0.6	0.7	0.0	-0.0
Illnesses of father: Heart disease	0.1	0.2	1.1	0.1	0.2	1.0	0.1	0.1	0.4	-0.2	-0.4
Ever had bowel cancer screening	0.1	0.2	0.9	-0.2	-0.3	-0.9	0.4	0.2	0.2	0.1	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.5	-0.6	-0.7	0.1	0.2	-0.2	0.2	-0.1	0.2
Ever taken oral contraceptive pill	0.1	0.1	0.6	0.8	0.3	-0.0	-0.1	-0.2	-0.2	0.1	-0.4
Illnesses of father: High blood pressure	0.1	0.2	0.6	-0.5	-0.8	0.2	-0.1	-0.5	-0.1	-0.3	-0.2
Fractured/broken bones in last 5 years	0.1	0.1	0.5	-0.1	-0.1	-0.4	0.5	0.0	0.7	0.5	0.2

Hub : Genes

YIF1A

Models

Trait associations