Best TWAS P=2.43e-08 · Best GWAS P=9.43e-10 conditioned to 0.000127
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | FBXO31 | 0.08 | 0.09 | lasso | 5 | 0.08 | 4.0e-07 | 5.3 | 5.5 | 4.6e-08 | 0.52 | 0.18 | 0.81 | FALSE |
| 2 | GTEx | Uterus | SNAI3-AS1 | 0.47 | 0.00 | enet | 13 | 0.04 | 5.3e-02 | 3.3 | -5.6 | 2.5e-08 | -0.01 | 0.03 | 0.11 | TRUE |
| 3 | METSIM | Adipose | MAP1LC3B | 0.09 | 0.07 | enet | 11 | 0.06 | 2.1e-09 | 5.6 | -5.2 | 1.6e-07 | -0.58 | 0.04 | 0.96 | FALSE |
| 4 | NTR | Blood | MAP1LC3B | 0.05 | 0.02 | lasso | 8 | 0.03 | 1.6e-10 | 3.7 | -5.6 | 2.4e-08 | -0.59 | 0.09 | 0.91 | TRUE |
| 5 | YFS | Blood | MVD | 0.02 | 0.00 | bslmm | 333 | 0.01 | 2.2e-03 | 4.6 | -5.4 | 7.3e-08 | 0.07 | 0.02 | 0.29 | TRUE |