TWAS
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Traits
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Traits
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Neuroticism
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chr16:86,667,409-89,448,663
Best TWAS P=2.43e-08 · Best GWAS P=9.43e-10 conditioned to 0.000127
87M
87.5M
88M
88.5M
89M
89.5M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
NTR
Blood
MAP1LC3B
0.05
0.02
lasso
8
0.03
1.6e-10
3.7
-5.6
2.4e-08
-0.59
0.09
0.91
TRUE
2
GTEx
Uterus
SNAI3-AS1
0.47
0.00
enet
13
0.04
5.3e-02
3.3
-5.6
2.5e-08
-0.01
0.03
0.11
TRUE
5
YFS
Blood
MVD
0.02
0.00
bslmm
333
0.01
2.2e-03
4.6
-5.4
7.3e-08
0.07
0.02
0.29
TRUE
1
GTEx
Skin Sun Exposed Lower leg
FBXO31
0.08
0.09
lasso
5
0.08
4.0e-07
5.3
5.5
4.6e-08
0.52
0.18
0.81
FALSE
3
METSIM
Adipose
MAP1LC3B
0.09
0.07
enet
11
0.06
2.1e-09
5.6
-5.2
1.6e-07
-0.58
0.04
0.96
FALSE