Best TWAS P=6.81e-10 · Best GWAS P=1.11e-10 conditioned to 0.0538
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | SLC25A17 | 0.09 | 0.03 | enet | 10 | 0.06 | 4.2e-05 | 6.1 | 6.0 | 1.9e-09 | 0.84 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Esophagus Mucosa | RANGAP1 | 0.07 | 0.02 | lasso | 4 | 0.02 | 8.6e-03 | 6.2 | -6.2 | 6.8e-10 | -0.93 | 0.02 | 0.93 | TRUE |
| 3 | GTEx | Nerve Tibial | ACO2 | 0.06 | 0.05 | lasso | 5 | 0.04 | 8.5e-04 | 4.6 | 5.7 | 1.5e-08 | 0.80 | 0.58 | 0.34 | FALSE |
| 4 | GTEx | Pituitary | L3MBTL2 | 0.19 | 0.15 | enet | 17 | 0.19 | 1.6e-05 | -5.6 | 5.5 | 3.2e-08 | 0.68 | 0.18 | 0.57 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | L3MBTL2 | 0.05 | 0.03 | enet | 9 | 0.04 | 1.8e-04 | 6.2 | 6.1 | 8.0e-10 | 0.89 | 0.01 | 0.98 | FALSE |