[Hub]/) : Traits : Neuroticism : ←

chr22:40,472,399-42,614,362

Best TWAS P=6.81e-10 · Best GWAS P=1.11e-10 conditioned to 0.0538

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Esophagus Mucosa	RANGAP1	0.07	0.02	lasso	4	0.02	8.6e-03	6.2	-6.2	6.8e-10	-0.93	0.02	0.93	TRUE
5	The Cancer Genome Atlas	Thyroid Carcinoma	L3MBTL2	0.05	0.03	enet	9	0.04	1.8e-04	6.2	6.1	8.0e-10	0.89	0.01	0.98	FALSE
1	GTEx	Cells Transformed fibroblasts	SLC25A17	0.09	0.03	enet	10	0.06	4.2e-05	6.1	6.0	1.9e-09	0.84	0.02	0.98	FALSE
3	GTEx	Nerve Tibial	ACO2	0.06	0.05	lasso	5	0.04	8.5e-04	4.6	5.7	1.5e-08	0.80	0.58	0.34	FALSE
4	GTEx	Pituitary	L3MBTL2	0.19	0.15	enet	17	0.19	1.6e-05	-5.6	5.5	3.2e-08	0.68	0.18	0.57	FALSE