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chr5:59,353,199-61,145,102

Best TWAS P=1.47e-09 · Best GWAS P=9.33e-10 conditioned to 0.0469

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ELOVL7	0.19	0.10	enet	17	0.17	1.7e-08	5.1	-6.0	1.5e-09	-0.83	0.01	0.99	TRUE
12	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ERCC8	0.11	0.07	enet	6	0.09	2.0e-04	5.5	5.9	4.2e-09	0.87	0.01	0.96	FALSE
6	The Cancer Genome Atlas	Colon Adenocarcinoma	ERCC8	0.09	0.09	lasso	1	0.08	2.1e-05	5.7	5.7	1.3e-08	0.93	0.00	0.98	FALSE
5	The Cancer Genome Atlas	Breast Invasive Carcinoma	ELOVL7	0.02	0.01	lasso	3	0.01	2.2e-03	5.1	-5.6	2.3e-08	-0.82	0.01	0.97	FALSE
2	GTEx	Esophagus Mucosa	ELOVL7	0.08	0.04	enet	12	0.05	3.5e-04	5.1	-5.6	2.4e-08	-0.75	0.05	0.78	FALSE
8	The Cancer Genome Atlas	Brain Lower Grade Glioma	NDUFAF2	0.06	0.04	lasso	3	0.03	1.2e-04	5.3	5.5	4.3e-08	0.82	0.12	0.84	FALSE
11	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ERCC8	0.06	0.03	blup	39	0.03	2.8e-04	5.7	5.5	4.4e-08	0.84	0.00	0.98	FALSE
1	GTEx	Cells Transformed fibroblasts	ERCC8	0.08	0.04	lasso	6	0.05	1.7e-04	4.3	5.5	4.6e-08	0.84	0.02	0.97	FALSE
10	The Cancer Genome Atlas	Lung Adenocarcinoma	ERCC8	0.04	0.01	blup	39	0.01	8.1e-03	5.7	5.4	5.6e-08	0.76	0.01	0.81	FALSE
3	GTEx	Stomach	ELOVL7	0.15	0.14	enet	14	0.16	4.7e-08	4.6	-5.4	7.9e-08	-0.73	0.05	0.93	FALSE
4	ROSMAP	Brain Pre-frontal Cortex	NDUFAF2	0.08	0.06	enet	15	0.07	1.9e-09	5.1	5.3	9.2e-08	0.76	0.22	0.78	FALSE
13	The Cancer Genome Atlas	Soft Tissue Sarcoma	ELOVL7	0.12	0.05	lasso	1	0.06	1.4e-04	5.3	-5.3	1.1e-07	-0.69	0.01	0.98	FALSE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NDUFAF2	0.10	0.09	lasso	6	0.09	1.1e-10	5.4	5.3	1.2e-07	0.73	0.25	0.75	FALSE