[Hub]/) : Traits : Smoking Status : ← →

chr5:59,353,199-61,145,102

Best TWAS P=1.47e-09 · Best GWAS P=9.33e-10 conditioned to 0.0469

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts ERCC8 0.08 0.04 lasso 6 0.05 1.7e-04 4.3 5.5 4.6e-08 0.84 0.02 0.97 FALSE
2 GTEx Esophagus Mucosa ELOVL7 0.08 0.04 enet 12 0.05 3.5e-04 5.1 -5.6 2.4e-08 -0.75 0.05 0.78 FALSE
3 GTEx Stomach ELOVL7 0.15 0.14 enet 14 0.16 4.7e-08 4.6 -5.4 7.9e-08 -0.73 0.05 0.93 FALSE
4 ROSMAP Brain Pre-frontal Cortex NDUFAF2 0.08 0.06 enet 15 0.07 1.9e-09 5.1 5.3 9.2e-08 0.76 0.22 0.78 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma ELOVL7 0.02 0.01 lasso 3 0.01 2.2e-03 5.1 -5.6 2.3e-08 -0.82 0.01 0.97 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma ERCC8 0.09 0.09 lasso 1 0.08 2.1e-05 5.7 5.7 1.3e-08 0.93 0.00 0.98 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NDUFAF2 0.10 0.09 lasso 6 0.09 1.1e-10 5.4 5.3 1.2e-07 0.73 0.25 0.75 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma NDUFAF2 0.06 0.04 lasso 3 0.03 1.2e-04 5.3 5.5 4.3e-08 0.82 0.12 0.84 FALSE
9 The Cancer Genome Atlas Liver Hepatocellular Carcinoma ELOVL7 0.19 0.10 enet 17 0.17 1.7e-08 5.1 -6.0 1.5e-09 -0.83 0.01 0.99 TRUE
10 The Cancer Genome Atlas Lung Adenocarcinoma ERCC8 0.04 0.01 blup 39 0.01 8.1e-03 5.7 5.4 5.6e-08 0.76 0.01 0.81 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ERCC8 0.06 0.03 blup 39 0.03 2.8e-04 5.7 5.5 4.4e-08 0.84 0.00 0.98 FALSE
12 The Cancer Genome Atlas Pancreatic Adenocarcinoma ERCC8 0.11 0.07 enet 6 0.09 2.0e-04 5.5 5.9 4.2e-09 0.87 0.01 0.96 FALSE
13 The Cancer Genome Atlas Soft Tissue Sarcoma ELOVL7 0.12 0.05 lasso 1 0.06 1.4e-04 5.3 -5.3 1.1e-07 -0.69 0.01 0.98 FALSE