Best TWAS P=3.88e-09 · Best GWAS P=1.32e-08 conditioned to 0.0211
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | MADD | 0.09 | 0.03 | enet | 22 | 0.04 | 1.9e-03 | -5.1 | 5.2 | 2.2e-07 | 0.45 | 0.06 | 0.53 | FALSE |
2 | GTEx | Breast Mammary Tissue (Female) | PSMC3 | 0.02 | 0.01 | lasso | 1 | 0.04 | 2.5e-02 | 5.1 | -5.1 | 2.8e-07 | -0.72 | 0.02 | 0.22 | FALSE |
3 | NTR | Blood | PTPRJ | 0.04 | 0.01 | blup | 285 | 0.02 | 8.5e-08 | 5.1 | 5.9 | 3.9e-09 | 0.68 | 0.04 | 0.96 | TRUE |