[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr15:39,955,786-42,957,373

Best TWAS P=1.89e-14 · Best GWAS P=1.83e-11 conditioned to 0.00262

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	JMJD7	0.10	0.06	bslmm	419	0.07	2.4e-09	6.5	6.5	7.7e-11	0.84	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MAPKBP1	0.10	0.06	enet	15	0.10	9.6e-13	6.7	-5.7	1.4e-08	-0.82	0.02	0.98	FALSE
3	GTEx	Adipose Subcutaneous	PLA2G4B	0.06	0.00	enet	11	0.00	6.9e-01	-4.2	5.9	2.8e-09	0.77	0.03	0.81	FALSE
4	GTEx	Artery Aorta	MAPKBP1	0.12	0.00	lasso	5	0.00	6.2e-01	4.8	-6.4	1.4e-10	-0.82	0.02	0.85	FALSE
5	GTEx	Artery Aorta	PLA2G4B	0.10	0.02	lasso	3	0.02	3.9e-02	6.6	6.6	4.2e-11	0.95	0.02	0.84	FALSE
6	GTEx	Artery Aorta	RP11-23P13.4	0.10	0.02	lasso	4	0.02	2.7e-02	4.8	-5.7	9.5e-09	-0.65	0.12	0.40	FALSE
7	GTEx	Artery Tibial	EHD4	0.14	0.03	enet	21	0.06	1.0e-05	4.4	-6.7	2.4e-11	-0.63	0.16	0.80	FALSE
8	GTEx	Artery Tibial	MAPKBP1	0.07	0.01	lasso	6	0.00	4.3e-01	-5.0	-5.5	3.1e-08	-0.74	0.05	0.90	FALSE
9	GTEx	Brain Cerebellum	MAPKBP1	0.23	0.09	lasso	8	0.12	2.2e-04	6.5	-7.3	2.8e-13	-0.91	0.01	0.97	FALSE
10	GTEx	Brain Cerebellum	RP11-23P13.4	0.19	0.05	enet	13	0.10	7.6e-04	6.5	-7.3	2.8e-13	-0.90	0.02	0.90	FALSE
11	GTEx	Brain Cortex	MAPKBP1	0.29	0.00	enet	21	0.04	2.7e-02	-5.3	-5.8	6.3e-09	-0.82	0.04	0.79	FALSE
12	GTEx	Esophagus Muscularis	RP11-64K12.8	0.10	0.00	enet	13	0.00	4.6e-01	-1.6	5.2	1.9e-07	0.14	0.04	0.21	TRUE
13	GTEx	Nerve Tibial	EHD4	0.20	0.04	lasso	7	0.08	2.4e-06	5.7	-6.7	1.7e-11	-0.50	0.78	0.19	FALSE
14	GTEx	Nerve Tibial	MAPKBP1	0.09	0.05	lasso	3	0.08	3.5e-06	6.6	-6.3	3.1e-10	-0.89	0.01	0.99	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	PLA2G4B	0.17	0.18	lasso	5	0.18	2.9e-10	6.5	6.7	2.6e-11	0.98	0.01	0.99	FALSE
16	GTEx	Skin Not Sun Exposed Suprapubic	RP11-23P13.7	0.11	0.07	lasso	7	0.06	2.3e-04	-4.3	5.6	1.8e-08	0.62	0.04	0.92	FALSE
17	GTEx	Skin Sun Exposed Lower leg	PLA2G4B	0.16	0.18	lasso	3	0.17	2.5e-14	6.5	6.6	5.4e-11	0.97	0.01	0.99	FALSE
18	GTEx	Thyroid	PLA2G4B	0.14	0.09	enet	11	0.08	1.6e-06	6.7	7.7	1.9e-14	0.90	0.01	0.99	TRUE
19	GTEx	Vagina	SPTBN5	0.22	0.03	lasso	6	0.04	4.2e-02	-4.2	6.1	1.3e-09	0.65	0.06	0.41	FALSE
20	METSIM	Adipose	DISP2	0.38	0.22	bslmm	397	0.29	2.9e-43	6.2	5.6	2.3e-08	0.06	0.00	1.00	TRUE
21	METSIM	Adipose	JMJD7	0.16	0.20	lasso	11	0.22	5.6e-32	-5.3	5.4	5.8e-08	0.76	0.98	0.02	FALSE
22	METSIM	Adipose	MAPKBP1	0.08	0.03	lasso	10	0.02	1.1e-04	-4.7	-5.2	2.2e-07	-0.61	0.55	0.44	FALSE
23	YFS	Blood	PLA2G4B	0.07	0.11	bslmm	409	0.12	1.6e-35	6.7	5.8	6.8e-09	0.94	0.00	1.00	FALSE
24	YFS	Blood	RPAP1	0.08	0.10	lasso	5	0.09	3.6e-29	5.6	-5.6	2.0e-08	-0.54	0.80	0.20	FALSE
25	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	JMJD7-PLA2G4B	0.04	0.00	enet	8	0.01	2.8e-02	6.6	6.4	2.0e-10	0.88	0.00	0.91	FALSE
26	The Cancer Genome Atlas	Breast Invasive Carcinoma	DISP2	0.31	0.22	lasso	8	0.31	3.7e-64	6.2	5.4	5.5e-08	0.07	0.00	1.00	FALSE
27	The Cancer Genome Atlas	Glioblastoma Multiforme	SPTBN5	0.21	0.07	blup	78	0.12	2.3e-04	-3.9	5.2	2.2e-07	0.64	0.28	0.24	FALSE
28	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	JMJD7-PLA2G4B	0.04	0.02	lasso	3	0.02	1.9e-03	6.5	6.5	8.0e-11	0.97	0.00	0.95	FALSE
29	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DISP2	0.39	0.24	enet	11	0.34	5.0e-20	6.2	5.1	3.0e-07	0.09	0.00	1.00	FALSE
30	The Cancer Genome Atlas	Brain Lower Grade Glioma	DISP2	0.17	0.10	enet	16	0.15	9.9e-17	6.2	5.2	1.8e-07	0.06	0.00	1.00	FALSE
31	The Cancer Genome Atlas	Brain Lower Grade Glioma	JMJD7-PLA2G4B	0.07	0.02	enet	7	0.03	3.2e-04	6.5	5.9	3.5e-09	0.82	0.00	0.96	FALSE
32	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	DISP2	0.37	0.18	enet	9	0.21	2.4e-10	6.2	5.5	3.8e-08	0.07	0.00	1.00	FALSE
33	The Cancer Genome Atlas	Lung Adenocarcinoma	DISP2	0.30	0.15	lasso	5	0.28	2.7e-32	6.2	5.3	1.2e-07	0.06	0.00	1.00	FALSE
34	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	DISP2	0.31	0.23	enet	5	0.28	2.8e-19	6.2	5.8	6.6e-09	0.11	0.00	1.00	FALSE
35	The Cancer Genome Atlas	Prostate Adenocarcinoma	DISP2	0.45	0.40	lasso	8	0.45	3.1e-52	6.2	5.8	5.7e-09	0.09	0.00	1.00	TRUE
36	The Cancer Genome Atlas	Testicular Germ Cell Tumors	DISP2	0.37	0.26	lasso	4	0.28	2.4e-10	6.2	5.8	7.9e-09	0.11	0.00	1.00	FALSE
37	The Cancer Genome Atlas	Thyroid Carcinoma	DISP2	0.35	0.25	enet	17	0.32	3.0e-31	6.2	5.4	8.3e-08	0.06	0.00	1.00	FALSE