TWAS hub - JMJD7-PLA2G4B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.0410	0.0250	0.00600	0.004	0.012	0.013	NA	0.006	0.1300	0.0330	0.02800	NA	0.0890
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0440	0.0265	0.00270	0.016	0.013	0.007	NA	0.021	0.0060	0.0130	0.04400	NA	0.0019
3	TCGA	Brain Lower Grade Glioma	0.0672	0.0348	0.00047	0.021	0.021	0.028	NA	0.013	0.0018	0.0017	0.00032	NA	0.0100

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Lung FEV1/FVC ratio	17.5	88.6	112.4	8.9	8.6	10.6
Diastolic blood pressure, automated reading	15.7	48.6	53.0	6.8	6.8	7.3
Qualifications: NVQ or HND or HNC or equivalent	14.0	16.9	19.5	3.6	4.3	4.4
Medication: Gliclazide	10.0	11.3	14.4	3.8	3.6	2.6
Waist Hip Ratio (WHR)	8.7	39.2	42.3	6.4	6.5	5.9
Triglycerides	8.6	14.1	15.1	3.9	3.7	3.7
Number of full brothers	8.4	10.5	13.6	3.7	2.9	3.1
Diabetes diagnosed by doctor	8.1	13.3	17.3	4.2	4.0	2.7
Systolic Blood Pressure	7.4	37.2	43.0	6.0	6.6	5.7
Medication: Metformin	7.3	10.3	12.5	3.5	3.5	2.5
HDL Cholesterol	7.2	12.0	12.7	-3.4	-3.6	-3.5
Type 2 Diabetes (T2D) (2018)	7.1	13.3	17.7	3.9	4.2	2.7
Alcohol drinker status: Never	7.0	8.4	9.8	3.1	3.1	2.4
Father’s age at death	6.5	8.8	11.2	-2.9	-2.6	-3.4
Reaction Time	6.3	11.9	13.8	3.6	3.7	3.0
Diabetes (self-reported)	6.3	9.8	13.0	3.6	3.6	1.9
Diabetes (mother)	5.7	7.3	10.8	2.4	2.3	3.3
Number of treatments/medications taken	5.5	9.8	15.3	3.9	3.1	2.2
Supplements: Zinc	5.5	6.0	9.2	2.0	2.2	3.0
High blood pressure (mother)	5.5	7.7	10.2	2.6	3.2	2.5
Wears glasses or contact lenses	5.4	6.2	9.0	-1.9	-2.4	-3.0
Diabetes (father)	5.2	6.4	11.1	2.3	1.7	3.3
Medication: Paracetamol	5.0	8.3	9.7	2.9	3.1	2.6
Medication: Paracetamol	4.9	7.6	8.4	2.9	2.9	2.5
Alcohol usually taken with meals	4.8	7.8	8.8	-2.8	-3.0	-2.6
Cardiovascular Disease	4.7	15.4	18.7	4.3	4.0	3.3
Medication: Bendroflumethiazide	4.7	7.1	11.4	1.9	2.5	3.4
Bilateral oophorectomy (both ovaries removed)	4.6	5.3	7.1	1.9	2.7	2.3
Mother’s age at death	4.5	5.6	7.2	-2.5	-2.7	-1.7
Impedance of leg (right)	4.3	21.0	25.9	5.0	5.1	3.5
High blood pressure	4.3	11.9	14.5	3.8	3.5	3.0
Breast cancer (self-reported)	4.3	5.1	7.0	-1.9	-2.1	-2.6
Medication for pain relief, constipation, heartburn	4.2	7.2	10.9	-3.3	-2.7	-1.9
Mouth/teeth dental problems: Bleeding gums	4.1	5.3	5.8	-2.1	-2.4	-2.4
Systolic blood pressure, automated reading	3.9	11.3	11.4	3.4	3.3	3.4
Tinnitus: Yes, but not now, but have in the past	3.9	4.2	5.7	2.0	2.4	1.6
Major Depression (MDD)	3.8	4.6	5.8	2.3	2.4	1.7
Average weekly champagne plus white wine intake	3.7	5.1	5.9	-2.3	-2.1	-2.4
Hypertension (Self-reported)	3.6	10.1	12.3	3.5	3.3	2.6
Neuroticism (2016)	3.5	5.1	7.6	2.7	2.3	1.6
Age when periods started (menarche)	3.5	8.3	11.1	2.3	2.9	3.3
Headache pain in last month	3.4	5.8	10.5	1.7	2.0	3.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.4	4.0	6.3	2.5	2.1	1.1
Bipolar Disorder (2011)	3.3	3.2	5.3	1.0	1.8	2.3
Crohns Disease (2012)	3.3	5.3	6.6	-2.6	-2.6	-1.6
Hearing difficulty/problems: Yes	3.3	5.0	6.2	-2.5	-2.3	-1.9
Medication: Ramipril	3.3	4.2	6.0	1.6	2.4	2.0
Medication: Amlodipine	3.3	4.6	5.7	2.4	2.3	1.6
Angina (self-reported)	3.3	4.4	7.3	-1.1	-2.2	-2.7
Hypothyroidism/myxoedema (self-reported)	3.2	6.3	8.2	2.9	2.1	2.5
Age at last live birth	3.2	4.7	6.3	-2.5	-2.3	-1.6
Impedance of leg (left)	3.1	14.9	19.5	4.1	4.4	2.9
Medication: Levothyroxine sodium	2.9	4.9	7.0	2.6	2.1	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	2.9	9.3	19.8	1.4	2.5	4.5
Mean time to correctly identify matches	2.9	5.6	7.5	2.7	2.7	1.4
Ever had hysterectomy (womb removed)	2.8	3.1	5.5	1.9	2.4	0.5
Had other major operations	2.8	3.5	4.5	-2.1	-2.0	-1.4
Financial difficulties in last 2 years	2.8	3.7	4.1	1.9	1.9	2.0
Mineral and other dietary supplements	2.8	3.7	3.8	-1.9	-1.9	-2.0
Vascular/heart problems diagnosed by doctor	2.8	7.7	9.9	-3.1	-2.8	-2.4
Hypothyroidism (self reported)	2.7	6.1	9.5	3.1	1.9	2.3
Eye problems/disorders: Diabetes related eye disease	2.7	3.0	3.5	1.8	1.9	1.4
Angina	2.7	3.6	6.0	-0.8	-2.0	-2.5
Hair/balding pattern: Pattern 4	2.7	6.6	7.4	-2.4	-2.6	-2.7
Number of full sisters	2.7	3.2	3.8	1.9	2.0	1.6
Illnesses of siblings: Diabetes	2.7	3.3	6.1	1.4	1.4	2.5
Number of self-reported non-cancer illnesses	2.7	4.7	6.5	2.4	2.5	1.4
Hearing difficulty/problems with background noise	2.6	4.2	5.7	-2.4	-2.0	-1.7
Leg pain on walking	2.6	3.2	5.1	2.2	1.6	1.4
Average weekly red wine intake	2.5	3.7	4.4	-2.1	-2.0	-1.6
Vitamin and mineral supplements	2.4	3.2	6.8	-1.2	-1.1	-2.6
Heel bone mineral density (BMD) T-score, automated (right)	2.4	5.5	5.7	-2.3	-2.3	-2.4
Medication for cholesterol, blood pressure or diabetes	2.4	4.1	5.2	-2.3	-1.9	-1.9
Glaucoma (self-reported)	2.4	2.8	3.9	-1.2	-2.0	-1.8
Impedance of whole body	2.4	12.4	16.4	3.7	4.0	2.7
Forced expiratory volume in 1-second (FEV1)	2.3	7.7	18.3	0.8	2.0	4.3
Alcohol intake frequency.	2.3	5.4	6.5	2.5	2.3	2.1
Medication: Ibuprofen (e.g. Nurofen)	2.2	2.8	3.6	1.9	1.8	1.2
Age at First Birth	2.1	3.0	4.0	-1.7	-2.0	-1.5
Severe depression (siblings)	2.1	2.4	3.7	-1.9	-1.4	-1.2
Blood Red Count	2.0	19.0	25.2	4.2	3.8	5.0
Serious illness, injury or assault to yourself	2.0	2.5	4.1	2.0	1.8	0.5
Reason for reducing amount of alcohol drunk: Health precaution	2.0	2.4	3.2	-1.8	-1.5	-1.3
Fractured/broken bones in last 5 years	2.0	2.6	4.2	2.0	1.2	1.4
Overall health rating	1.9	4.1	5.3	2.2	2.3	1.5
Commuting to job workplace: Cycle	1.9	2.4	4.4	-1.3	-1.0	-2.1
Heel T-Score	1.8	14.5	18.2	-3.0	-4.1	-4.3
Qualifications: CSEs or equivalent	1.8	2.4	3.3	0.9	1.7	1.8
Impedance of arm (right)	1.8	8.2	9.7	3.0	3.1	2.5
Peak expiratory flow (PEF)	1.8	4.1	11.6	0.3	0.7	3.4
Medication: Blood pressure	1.8	3.3	4.0	1.5	1.9	2.0
Osteoporosis (self-reported)	1.8	2.2	3.3	-1.3	-1.3	-1.8
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	3.2	1.5	1.8	1.1
Multivitamins +/- minerals	1.7	2.2	4.6	1.2	0.6	2.1
Long-standing illness, disability or infirmity	1.7	2.7	4.9	1.3	2.2	1.2
Supplements: Fish oil (including cod liver oil)	1.7	2.2	2.7	1.6	1.5	1.3
Ever had prostate specific antigen (PSA) test	1.7	1.9	3.5	1.9	1.0	1.1
Sensitivity / hurt feelings	1.6	2.8	3.6	1.2	1.8	1.9
Qualifications: A levels/AS levels or equivalent	1.6	3.4	4.3	-1.6	-2.1	-1.9
Leg fat-free mass (right)	1.6	8.8	13.9	-3.5	-3.7	-0.6
Commuting to job workplace: Walk	1.6	1.8	2.2	-1.4	-1.1	-1.5
Leg predicted mass (right)	1.6	8.7	13.8	-3.5	-3.7	-0.5
Breastfed as a baby	1.5	1.8	2.4	-1.6	-1.4	-1.1
Medication: Ibuprofen	1.5	1.8	3.1	1.8	1.4	0.6
Medication: Omeprazole	1.5	1.8	2.3	1.4	1.5	1.1
Intelligence (Savage-Jansen 2018)	1.4	4.2	5.9	-1.8	-2.4	-1.9
Ovarian Cancer	1.4	1.8	2.7	1.6	1.5	0.7
Time employed in main current job	1.4	1.6	2.1	1.1	1.4	1.2
Impedance of arm (left)	1.4	6.4	8.9	2.6	3.0	1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.1	2.6	1.6	1.5	1.3
Migraine (self-reported)	1.4	1.8	3.2	1.0	1.8	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.7	2.7	1.0	1.2	1.6
Illness, injury, bereavement, stress in last 2 years	1.4	1.7	2.2	-1.4	-1.5	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	1.8	1.0	1.3	1.3
Medication: Blood pressure	1.4	2.7	3.3	1.8	1.7	1.4
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	2.2	1.4	1.5	0.9
Lung FVC	1.3	6.5	13.4	-3.7	-2.3	-1.0
Ever used hormone-replacement therapy (HRT)	1.3	1.6	2.7	1.4	1.6	0.6
Current tobacco smoking	1.3	2.1	2.8	1.7	1.2	1.4
Medication: Simvastatin	1.3	1.9	4.0	2.0	1.3	-0.2
Mouth/teeth dental problems: Dentures	1.3	2.2	2.9	1.7	1.7	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.7	4.4	0.6	1.8	2.1
Guilty feelings	1.3	2.0	2.4	1.6	1.2	1.5
Irritability	1.3	2.1	3.8	-1.5	-1.9	-0.7
Leg fat-free mass (left)	1.2	6.5	10.5	-3.0	-3.2	-0.0
Taking other prescription medications	1.2	1.9	3.5	1.9	1.4	0.5
Leg predicted mass (left)	1.2	6.6	10.7	-3.0	-3.3	-0.1
Alcohol intake versus 10 years previously	1.2	1.8	1.9	1.2	1.4	1.4
Pulse rate	1.2	2.0	3.5	1.1	1.9	1.1
Medication: Cholesterol lowering	1.2	1.9	4.2	2.1	1.0	0.8
Birth weight of first child	1.2	2.1	3.1	1.1	1.4	1.8
Arm fat-free mass (right)	1.2	6.3	10.6	-2.8	-3.3	-0.5
Age at first live birth	1.2	2.1	3.5	-1.9	-1.6	-0.5
Arm predicted mass (right)	1.2	6.3	10.5	-2.9	-3.2	-0.2
Whole body fat-free mass	1.2	6.9	11.5	-3.0	-3.4	-0.3
Smoking status: Current	1.2	2.0	2.9	1.7	1.1	1.3
Whole body water mass	1.2	7.0	11.4	-3.1	-3.4	-0.3
High cholesterol (Self-reported)	1.2	2.2	5.2	2.3	1.0	0.5
Ulcerative Colitis	1.1	1.5	2.7	-1.6	-1.4	-0.2
Frequency of depressed mood in last 2 weeks	1.1	1.5	1.9	1.4	1.1	1.2
Number of live births	1.1	1.6	3.0	1.7	1.2	0.5
Birth weight	1.1	2.4	4.4	0.9	1.4	2.1
Handedness (chirality/laterality): Left-handed	1.1	1.3	2.5	-0.7	-1.0	-1.6
Basal metabolic rate	1.1	6.3	10.4	-2.9	-3.2	0.1
Arm fat-free mass (left)	1.1	5.7	9.8	-2.7	-3.1	-0.1
Pain experienced in last month	1.1	1.8	2.6	-1.0	-1.4	-1.6
Breast Cancer	1.0	2.4	2.9	-1.7	-1.5	-1.5
Pack years adult smoking proportion	1.0	1.5	1.8	1.3	1.1	1.3
Stomach or abdominal pain in last month	1.0	1.2	2.4	0.7	1.6	0.8
Trunk fat-free mass	1.0	5.5	9.4	-2.7	-3.1	-0.2
Falls in the last year	1.0	1.3	2.2	1.5	1.0	0.8
Trunk predicted mass	1.0	5.5	9.2	-2.7	-3.0	-0.2
Chronic bronchitis/emphysema (mother)	1.0	1.1	1.4	1.2	1.2	0.8
High blood pressure (siblings)	1.0	1.4	2.6	1.1	0.7	1.6
Illnesses of father: Heart disease	1.0	1.4	2.5	-0.1	-1.3	-1.6
Medication for cholesterol	1.0	1.6	2.2	-1.1	-1.1	-1.5
Arm predicted mass (left)	1.0	5.0	8.6	-2.5	-2.9	0.2
Mean Putamen Volume	0.9	1.0	1.9	-0.8	-1.4	-0.7
Fasting Glucose	0.9	1.1	1.3	0.9	1.1	1.1
Hayfever, allergic rhinitis or eczema	0.9	2.0	3.6	-0.2	-1.9	-1.6
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.5	2.0	1.4	1.3	0.9
Pain all over the body in last month	0.9	0.9	1.2	1.1	1.0	-0.7
Hip circumference	0.9	4.0	6.3	-2.3	-2.5	0.5
Exposure to tobacco smoke outside home	0.9	1.2	1.8	-1.3	-1.4	0.1
Verbal and Numeric Reasoning (VNR)	0.8	2.0	3.9	-1.2	-2.0	-0.9
Blood White Count	0.8	5.9	8.1	2.6	2.8	1.7
Average weekly spirits intake	0.8	1.0	2.8	-0.1	0.5	1.7
Medication for hormone replacement therapy	0.8	0.9	1.4	-1.2	-1.1	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	1.5	1.2	0.9	0.9
Sitting height	0.8	5.5	9.0	-2.6	-3.0	-0.9
Mouth/teeth dental problems	0.8	1.3	1.9	0.8	1.1	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	1.1	1.0	0.9	1.0
Ever smoked	0.8	1.4	1.6	-1.3	-1.1	-1.2
Age started oral contraceptive pill	0.8	1.0	2.0	-0.8	-1.4	-0.5
Ever depressed for a whole week	0.8	1.0	1.5	0.6	1.2	1.0
Pack years of smoking	0.8	1.1	1.6	1.3	0.9	1.0
Depressed Affect (Nagel 2018)	0.7	1.4	1.8	-1.1	-1.1	-1.3
BMI	0.7	4.0	7.6	-2.1	-2.8	0.3
Allergy or Eczema	0.7	1.9	3.0	-0.5	-1.7	-1.5
Chronotype (morning person)	0.7	1.7	2.7	-1.7	-0.7	-1.3
Waist circumference	0.7	2.7	7.3	0.8	0.4	2.7
Weight	0.7	3.7	6.1	-1.9	-2.5	1.1
Gout (self-reported)	0.7	1.0	1.2	-1.1	-1.1	-0.8
Worry too long after embarrassment	0.7	1.2	1.9	0.7	1.0	1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	1.9	0.7	0.5	1.4
Health satisfaction	0.7	0.9	1.5	1.2	1.1	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	4.0	0.2	0.2	2.0
Medication: Aspirin	0.7	0.9	1.8	1.3	0.3	-0.9
Financial situation satisfaction	0.7	0.9	1.7	1.3	0.8	0.6
Medication: Lisinopril	0.7	0.9	1.1	1.0	1.1	0.9
Crohns Disease (2017)	0.6	1.4	2.0	-1.4	-1.3	-0.8
Lupus	0.6	0.9	1.3	0.8	1.1	0.8
Smoking Status	0.6	1.6	2.7	1.6	1.0	1.0
Trunk fat percentage	0.6	2.3	6.8	0.2	-0.1	2.6
Townsend deprivation index at recruitment	0.6	0.8	1.6	0.4	1.2	0.8
Worrier / anxious feelings	0.6	1.1	1.8	0.4	1.1	1.4
Pulse wave Arterial Stiffness index	0.6	0.7	1.0	-0.4	-1.0	-1.0
Exposure to tobacco smoke at home	0.6	0.6	1.3	0.7	0.2	1.2
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	2.2	-0.2	-0.7	-1.5
Leg fat percentage (right)	0.6	2.3	5.9	0.7	0.6	2.4
Medication: Aspirin	0.6	0.8	1.8	1.3	0.5	-0.6
Knee pain experienced in last month	0.6	1.0	1.4	1.2	1.0	0.7
Alzheimer’s Disease (in father)	0.5	0.6	1.7	-1.3	-0.2	0.1
Irritable Bowel Disease (IBD)	0.5	1.2	2.0	-1.4	-1.2	-0.2
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.4	0.5	0.3	1.2
Medication: Co-codamol	0.5	0.6	1.2	0.6	1.1	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	1.2	-1.1	-1.1	-1.0
Trunk fat mass	0.5	2.1	5.1	-0.6	-0.9	2.2
Forced vital capacity (FVC)	0.5	1.9	3.6	-1.9	-0.7	1.3
Allergy	0.5	1.2	2.0	-0.2	1.4	1.2
Depression (self-reported)	0.5	0.7	0.9	-0.4	-1.0	-0.9
Ever highly irritable/argumentative for 2 days	0.5	0.6	0.9	1.0	0.7	0.7
Body fat percentage	0.5	1.9	5.8	0.1	-0.0	2.4
Wheeze or whistling in the chest in last year	0.5	0.9	1.8	1.3	0.9	0.4
Shortness of breath walking on level ground	0.5	0.7	1.5	1.2	0.6	-0.1
Qualifications: College or University degree	0.5	1.5	1.9	-1.2	-1.4	-1.1
Supplements: Vitamin C	0.5	0.5	1.5	0.2	0.3	1.2
Eye problems/disorders: Cataract	0.5	0.6	1.3	-1.1	-0.7	-0.2
Back pain experienced in last month	0.5	0.7	1.4	-1.2	-0.2	0.8
Medication: Atorvastatin	0.5	0.6	1.3	1.1	0.4	0.7
Hand grip strength (right)	0.4	1.0	2.9	0.0	-0.1	1.7
Relative age voice broke	0.4	0.6	1.4	0.4	-0.5	1.2
Chronic bronchitis/emphysema (father)	0.4	0.5	1.3	-0.1	0.3	-1.1
Body mass index (BMI)	0.4	1.8	3.1	-1.3	-1.8	0.8
Illnesses of siblings	0.4	0.5	1.0	-0.6	-0.5	-1.0
Arm fat percentage (right)	0.4	1.6	4.9	-0.1	-0.2	2.2
Lung cancer (father)	0.4	0.5	1.1	1.0	0.7	0.1
Arm fat mass (right)	0.4	1.7	3.5	-0.7	-1.1	1.9
Pulse wave reflection index	0.4	0.5	1.3	1.1	0.1	0.4
Blood clot in the leg (DVT)	0.4	0.5	0.9	0.9	0.8	0.0
Forced vital capacity (FVC), Best measure	0.4	1.5	2.9	-1.3	-0.0	1.7
Pulse wave peak to peak time	0.4	0.4	0.9	-0.0	0.6	0.9
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.1	-0.6	-1.1	-0.2
Whole body fat mass	0.4	1.8	4.2	-0.6	-0.9	2.0
Leg fat mass (right)	0.4	1.4	3.6	-0.3	-0.7	1.9
Comparative height size at age 10	0.4	2.1	3.4	1.1	1.3	1.8
Ever had bowel cancer screening	0.4	0.5	1.3	0.0	-0.5	-1.1
Arm fat mass (left)	0.4	1.6	2.7	-0.9	-1.1	1.6
Miserableness	0.4	0.6	0.8	-0.7	-0.8	-0.9
Commuting to job workplace: Public transport	0.4	0.5	1.2	0.6	1.1	0.2
Eye problems/disorders: Glaucoma	0.4	0.5	1.1	-0.1	-0.6	-1.1
Pain type(s) experienced in last month: Hip pain	0.4	0.6	0.9	0.5	0.9	0.7
Illnesses of father: High blood pressure	0.4	0.4	1.2	0.2	-0.2	1.1
Leg fat percentage (left)	0.4	1.4	4.2	0.1	0.1	2.0
Myopia	0.4	0.6	1.4	0.4	0.6	-1.2
Leg fat mass (left)	0.4	1.4	2.9	-0.7	-0.9	1.7
Bipolar Disorder (2018)	0.3	0.4	0.6	-0.8	-0.4	0.7
Prostate Cancer	0.3	0.4	0.9	1.0	0.7	0.1
Body Mass Index (BMI) (2010)	0.3	0.5	0.9	-0.9	-0.7	0.1
Neuroticism	0.3	0.8	1.3	-1.1	-0.9	-0.7
Maternal smoking around birth	0.3	0.4	0.8	0.3	0.5	0.9
Supplements: Glucosamine	0.3	0.4	0.5	-0.3	0.7	0.7
Number of incorrect matches in round	0.3	0.5	1.0	0.6	1.0	0.1
Qualifications: None of the above	0.3	0.6	1.0	-1.0	-0.8	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.6	0.6	-0.8	-0.6	-0.8
Noisy workplace	0.3	0.3	0.6	0.4	0.8	0.6
Medication: Lansoprazole	0.3	0.3	0.5	0.7	0.4	-0.5
Prospective memory result	0.3	0.4	0.7	0.9	0.3	0.5
Medication: Allopurinol	0.3	0.5	0.9	-0.3	-0.6	-1.0
Medication: Seretide 50 evohaler	0.3	0.3	0.5	-0.2	-0.6	-0.7
Pulse rate, automated reading	0.3	1.1	2.0	1.1	1.4	0.3
Arm fat percentage (left)	0.3	1.4	4.1	-0.2	-0.2	2.0
Illnesses of father: None of the above (group 1)	0.3	0.4	1.0	0.4	1.0	0.4
Unable to work because of sickness or disability	0.3	0.4	0.8	0.9	0.6	0.3
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	0.6	0.8	0.6	0.0
Bipolar Disorder or Schizophrenia	0.2	0.4	0.6	-0.8	-0.5	0.5
Schizophrenia vs Biploar Disorder	0.2	0.3	0.7	-0.1	-0.3	-0.8
Alzheimer’s Disease (including proxy)	0.2	0.3	0.6	-0.8	-0.5	0.3
HbA1C	0.2	0.3	0.3	0.6	0.4	0.5
Schizophrenia (2014)	0.2	0.4	0.5	-0.7	-0.5	0.7
Blood Eosinophil Count	0.2	1.2	3.2	1.8	-0.3	0.5
Height	0.2	3.5	8.2	-0.4	-2.9	1.5
Respiratory disease	0.2	0.4	0.7	0.9	0.2	0.6
Hand grip strength (left)	0.2	0.5	1.2	-0.6	0.0	1.1
Relative age of first facial hair	0.2	0.3	0.8	-0.0	-0.9	0.4
Average weekly fortified wine intake	0.2	0.2	0.7	-0.0	-0.0	-0.9
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.5	0.3	0.7	0.4
Fluid intelligence score	0.2	0.4	1.0	-0.4	-1.0	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.7	0.1	0.1	-0.9
Standing height	0.2	1.6	2.2	-1.2	-1.5	1.1
Emphysema/chronic bronchitis	0.2	0.2	0.5	0.7	-0.2	-0.3
Heart disease (mother)	0.2	0.2	0.4	-0.5	-0.6	-0.2
Chest pain or discomfort	0.2	0.2	0.5	0.7	0.4	-0.2
Loneliness, isolation	0.2	0.2	0.6	-0.0	0.2	0.8
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	0.6	-0.8	-0.7	-0.2
Ever taken oral contraceptive pill	0.2	0.2	0.5	-0.2	0.2	0.7
Hearing aid user	0.2	0.3	0.4	0.7	0.5	0.3
Number of operations (self-reported)	0.2	0.4	0.6	0.5	0.8	0.5
Average weekly beer plus cider intake	0.2	0.2	0.5	0.7	0.2	0.4
Cholesterol lowering medication	0.2	0.3	0.5	0.7	0.1	-0.7
Alzheimer’s Disease (in mother)	0.1	0.1	0.2	-0.1	-0.4	-0.1
Ulcerative Colitis (UC)	0.1	0.2	0.4	-0.6	-0.3	0.3
Coronary Artery Disease (CAD)	0.1	0.1	0.2	0.4	-0.2	-0.3
LDL Cholesterol	0.1	0.1	0.2	0.1	0.0	0.5
Primary Biliary Cirrhosis	0.1	0.1	0.4	0.0	0.1	0.6
Rheumatoid Arthritis	0.1	0.2	0.3	-0.6	0.2	0.5
Blood Platelet Count	0.1	0.6	1.4	0.5	0.5	-1.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.2	0.1	0.2	0.4
Medication: Atenolol	0.1	0.2	0.4	-0.2	-0.4	-0.6
Hair/balding pattern: Pattern 2	0.1	0.1	0.1	-0.4	-0.3	0.3
Had menopause	0.1	0.2	0.5	0.2	-0.0	-0.7
Heart attack	0.1	0.1	0.3	0.2	0.1	-0.5
Neuroticism score	0.1	0.2	0.4	-0.7	-0.4	-0.1
Hair/balding pattern: Pattern 3	0.1	0.1	0.2	0.5	0.2	0.3
Illnesses of mother	0.1	0.1	0.3	0.0	0.1	-0.5
Loud music exposure frequency	0.1	0.1	0.2	0.1	0.1	0.4
Number of children fathered	0.1	0.1	0.3	-0.5	0.0	-0.1
Had major operations	0.1	0.1	0.2	0.4	-0.3	0.1
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.2	-0.1	-0.4	0.2
Smoking status: Previous	0.1	0.1	0.1	0.3	0.3	0.3
Friendships satisfaction	0.1	0.1	0.2	0.4	0.4	-0.2
Qualifications: nursing, teaching	0.1	0.1	0.2	-0.1	-0.4	-0.4
Osteoarthritis (self-reported)	0.1	0.1	0.3	0.0	-0.2	0.5
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.4	0.1	0.6	-0.1
Risk taking	0.1	0.2	0.5	0.2	0.1	0.7
Supplements: Calcium	0.1	0.1	0.1	0.2	-0.4	0.1
Basal cell carcinoma (self-reported)	0.1	0.1	0.3	-0.0	-0.3	0.5
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.2	0.1	0.1	-0.4
Heart disease (siblings)	0.1	0.1	0.2	-0.5	0.1	-0.1
Alcohol drinker status: Previous	0.1	0.1	0.2	-0.2	-0.3	-0.4
Depression (Nagel 2018)	0.0	0.0	0.1	0.4	0.1	-0.1
Neuroticism (Nagel 2018)	0.0	0.1	0.1	-0.0	0.3	0.3
Schizophrenia (2018)	0.0	0.1	0.1	-0.3	-0.3	0.1
Worry (Nagel 2018)	0.0	0.1	0.2	-0.4	0.3	-0.1
Hair Pigment	0.0	0.1	0.3	-0.3	0.6	0.2
Tanning	0.0	0.1	0.4	-0.1	0.6	0.2
Fed-up feelings	0.0	0.0	0.1	0.1	-0.1	-0.3
Past tobacco smoking	0.0	0.0	0.1	0.0	0.1	0.3
Nervous feelings	0.0	0.1	0.2	-0.2	-0.2	-0.4
Hayfever/allergic rhinitis (self-reported)	0.0	0.0	0.1	0.2	0.3	0.1
Happiness	0.0	0.0	0.0	0.1	0.0	0.1
Asthma	0.0	0.1	0.1	0.4	0.1	0.4
Length of working week for main job	0.0	0.0	0.0	0.1	0.2	-0.2
Tense / ‘highly strung’	0.0	0.1	0.1	-0.3	0.0	0.3
Medication: Ventolin 100micrograms inhaler	0.0	0.1	0.1	0.3	0.3	-0.0
Comparative body size at age 10	0.0	0.0	0.1	0.1	-0.0	0.3
Eye problems/disorders: None of the above	0.0	0.0	0.0	0.0	0.1	0.2
Neck or shoulder pain in last month	0.0	0.1	0.1	0.2	-0.2	0.3
Suffer from ‘nerves’	0.0	0.1	0.2	-0.1	0.4	0.1
Family relationship satisfaction	0.0	0.0	0.1	0.3	0.1	-0.1
Mood swings	0.0	0.0	0.1	-0.3	0.1	0.2
Asthma (self-reported)	0.0	0.0	0.1	0.3	-0.1	0.1

Hub : Genes

JMJD7-PLA2G4B

Models

Trait associations