Hub : Genes

NMRAL1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1400 0.0300 5.6e-09 0.100 0.097 0.112 0.122 0.097 3.3e-12 6.7e-12 1.8e-13 1.4e-14 6.8e-12
2 GTEx Adipose Subcutaneous 0.3120 0.0480 0.0e+00 0.326 NA 0.335 NA 0.351 2.6e-27 NA 3.6e-28 NA 9.0e-30
3 GTEx Adipose Visceral Omentum 0.3560 0.0740 1.8e-10 0.271 NA 0.267 NA 0.246 2.1e-14 NA 3.7e-14 NA 4.9e-13
4 GTEx Artery Aorta 0.4290 0.0550 0.0e+00 0.421 NA 0.405 NA 0.421 5.4e-25 NA 7.3e-24 NA 4.7e-25
5 GTEx Artery Coronary 0.3980 0.0810 3.7e-08 0.338 NA 0.338 NA 0.339 3.8e-12 NA 3.8e-12 NA 3.4e-12
6 GTEx Artery Tibial 0.3792 0.0571 0.0e+00 0.303 NA 0.363 NA 0.346 4.1e-24 NA 1.2e-29 NA 4.9e-28
7 GTEx Brain Caudate basal ganglia 0.3270 0.0940 1.4e-03 0.047 NA -0.001 NA 0.046 1.8e-02 NA 3.5e-01 NA 1.9e-02
8 GTEx Brain Cerebellar Hemisphere 0.6230 0.0730 2.0e-14 0.658 NA 0.642 NA 0.683 5.8e-22 NA 4.4e-21 NA 2.2e-23
9 GTEx Brain Cerebellum 0.8070 0.0680 0.0e+00 0.552 NA 0.566 NA 0.622 2.4e-19 NA 4.8e-20 NA 4.6e-23
10 GTEx Brain Cortex 0.3230 0.0980 8.7e-04 0.080 NA 0.150 NA 0.184 3.1e-03 NA 6.2e-05 NA 8.4e-06
11 GTEx Brain Hippocampus 0.5859 0.1187 3.5e-04 0.152 NA 0.137 NA 0.234 2.1e-04 NA 4.2e-04 NA 3.2e-06
12 GTEx Brain Nucleus accumbens basal ganglia 0.2600 0.0880 3.7e-03 0.020 NA 0.078 NA 0.010 9.5e-02 NA 4.0e-03 NA 1.7e-01
13 GTEx Breast Mammary Tissue 0.1690 0.0500 9.4e-05 0.179 NA 0.119 NA 0.148 1.6e-09 NA 1.2e-06 NA 5.2e-08
14 GTEx Breast Mammary Tissue (Male) 0.1962 0.0961 4.1e-02 0.107 NA 0.071 NA 0.102 1.9e-03 NA 1.0e-02 NA 2.4e-03
15 GTEx Breast Mammary Tissue (Female) 0.2884 0.1019 2.5e-03 0.011 NA -0.003 NA 0.002 1.5e-01 NA 4.0e-01 NA 2.7e-01
16 GTEx Cells Transformed fibroblasts 0.1450 0.0380 1.9e-06 0.116 NA 0.110 NA 0.124 4.9e-09 NA 1.3e-08 NA 1.6e-09
17 GTEx Colon Sigmoid 0.4310 0.0810 1.4e-08 0.354 NA 0.186 NA 0.308 2.4e-13 NA 3.8e-07 NA 1.7e-11
18 GTEx Colon Transverse 0.3820 0.0760 2.0e-09 0.187 NA 0.189 NA 0.189 2.8e-09 NA 2.3e-09 NA 2.4e-09
19 GTEx Esophagus Gastroesophageal Junction 0.4660 0.0850 1.1e-09 0.280 NA 0.248 NA 0.265 1.1e-10 NA 1.8e-09 NA 4.3e-10
20 GTEx Esophagus Mucosa 0.2260 0.0590 4.8e-07 0.130 NA 0.087 NA 0.118 5.5e-09 NA 1.9e-06 NA 2.7e-08
21 GTEx Esophagus Muscularis 0.3040 0.0520 8.3e-16 0.354 NA 0.333 NA 0.325 2.1e-22 NA 7.2e-21 NA 2.5e-20
22 GTEx Heart Atrial Appendage 0.2740 0.0800 1.1e-05 0.253 NA 0.220 NA 0.230 1.0e-11 NA 3.2e-10 NA 1.1e-10
23 GTEx Heart Left Ventricle 0.3640 0.0644 1.4e-12 0.261 NA 0.277 NA 0.272 3.4e-14 NA 4.4e-15 NA 8.5e-15
24 GTEx Lung 0.1609 0.0520 5.0e-05 0.106 NA 0.131 NA 0.122 1.7e-08 NA 3.4e-10 NA 1.4e-09
25 GTEx Muscle Skeletal 0.2724 0.0447 0.0e+00 0.217 NA 0.306 NA 0.292 5.4e-21 NA 2.0e-30 NA 6.4e-29
26 GTEx Nerve Tibial 0.3200 0.0514 2.2e-16 0.368 NA 0.348 NA 0.365 3.1e-27 NA 1.8e-25 NA 5.2e-27
27 GTEx Ovary 0.3260 0.1250 2.6e-03 0.156 NA 0.058 NA 0.121 1.2e-04 NA 1.6e-02 NA 7.0e-04
28 GTEx Pancreas 0.3110 0.0820 1.5e-06 0.118 NA 0.127 NA 0.126 1.2e-05 NA 5.4e-06 NA 5.9e-06
29 GTEx Pituitary 0.3130 0.0860 7.1e-05 0.175 NA 0.229 NA 0.155 3.7e-05 NA 1.9e-06 NA 1.1e-04
30 GTEx Skin Not Sun Exposed Suprapubic 0.1850 0.0580 1.1e-04 0.125 NA 0.084 NA 0.110 2.5e-07 NA 2.2e-05 NA 1.3e-06
31 GTEx Skin Sun Exposed Lower leg 0.1160 0.0380 1.2e-04 0.050 NA 0.043 NA 0.039 5.3e-05 NA 1.6e-04 NA 3.4e-04
32 GTEx Spleen 0.3470 0.1160 2.3e-03 0.199 NA 0.119 NA 0.227 7.8e-06 NA 5.9e-04 NA 1.6e-06
33 GTEx Stomach 0.1640 0.0570 1.3e-03 0.184 NA 0.109 NA 0.156 3.7e-09 NA 6.6e-06 NA 6.5e-08
34 GTEx Testis 0.2720 0.0660 9.7e-08 0.195 NA 0.225 NA 0.218 4.8e-09 NA 2.4e-10 NA 4.8e-10
35 GTEx Thyroid 0.1760 0.0490 1.2e-07 0.138 NA 0.128 NA 0.147 1.0e-10 NA 5.3e-10 NA 2.4e-11
36 GTEx Whole Blood 0.1890 0.0380 1.4e-10 0.135 NA 0.179 NA 0.200 2.0e-12 NA 2.6e-16 NA 3.6e-18
37 METSIM Adipose 0.1791 0.0325 0.0e+00 0.221 0.194 0.223 0.223 0.222 2.0e-32 2.6e-28 1.0e-32 8.8e-33 1.1e-32
38 ROSMAP Brain Pre-frontal Cortex 0.3142 0.0429 0.0e+00 0.254 0.271 0.295 0.253 0.305 2.1e-32 6.8e-35 2.7e-38 3.1e-32 8.0e-40
39 YFS Blood 0.2533 0.0297 0.0e+00 0.225 0.274 0.314 0.248 0.317 3.3e-72 6.7e-90 1.6e-105 2.3e-80 6.7e-107
40 TCGA Breast Invasive Carcinoma 0.0533 0.0340 2.4e-05 0.024 0.023 0.010 NA 0.022 6.9e-06 1.5e-05 2.7e-03 NA 2.2e-05
41 TCGA Kidney Renal Clear Cell Carcinoma 0.1211 0.0476 7.0e-10 0.054 0.086 0.092 NA 0.079 9.9e-07 6.7e-10 1.7e-10 NA 3.4e-09
42 TCGA Kidney Renal Papillary Cell Carcinoma 0.1080 0.0710 1.9e-03 0.055 0.019 0.012 NA 0.037 4.4e-04 2.8e-02 6.2e-02 NA 3.5e-03
43 TCGA Brain Lower Grade Glioma 0.1721 0.0545 0.0e+00 0.198 0.202 0.208 NA 0.205 4.8e-22 1.6e-22 3.3e-23 NA 7.9e-23
44 TCGA Lung Adenocarcinoma 0.0627 0.0331 2.3e-05 0.007 0.003 0.000 NA 0.001 4.1e-02 1.2e-01 3.3e-01 NA 2.3e-01
45 TCGA Lung Squamous Cell Carcinoma 0.0508 0.0262 1.9e-05 0.029 0.040 0.037 NA 0.037 2.6e-04 2.1e-05 4.3e-05 NA 4.1e-05
46 TCGA Pancreatic Adenocarcinoma 0.1730 0.0760 1.8e-05 0.040 0.118 0.115 NA 0.102 8.6e-03 1.2e-05 1.5e-05 NA 4.6e-05
47 TCGA Pheochromocytoma and Paraganglioma 0.6920 0.1170 1.0e-04 0.044 0.058 0.042 NA 0.090 7.6e-03 2.5e-03 8.7e-03 NA 2.0e-04
48 TCGA Prostate Adenocarcinoma 0.0669 0.0355 1.8e-05 0.056 0.054 0.047 NA 0.045 1.7e-06 2.5e-06 1.0e-05 NA 1.5e-05
49 TCGA Stomach Adenocarcinoma 0.0670 0.0340 4.5e-04 0.051 0.050 0.049 NA 0.054 1.4e-04 1.6e-04 1.9e-04 NA 9.0e-05
50 TCGA Testicular Germ Cell Tumors 0.1820 0.0870 2.5e-04 0.014 0.108 0.095 NA 0.078 1.0e-01 1.2e-04 3.1e-04 NA 1.1e-03
51 TCGA Thyroid Carcinoma 0.2220 0.0690 2.6e-15 0.130 0.151 0.171 NA 0.160 1.4e-12 1.5e-14 2.2e-16 NA 2.5e-15

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51
Bipolar Disorder (2018) 0.4 0.7 4.6 1.3 0.5 -0.4 0.5 0.5 0.6 0.6 0.1 -0.3 2.1 1.1 0.5 0.3 0.7 0.8 0.6 0.3 0.3 0.5 0.5 0.3 0.2 -0.2 0.2 -0.7 0.3 1.0 -0.1 0.0 0.1 0.9 0.4 0.2 0.2 -0.7 1.1 0.2 0.5 1.1 1.4 0.9 0.0 0.9 1.4 1.0 1.3 1.1 1.5 1.4 1.4 0.0
Bipolar Disorder or Schizophrenia 2.5 6.0 10.2 0.3 3.1 2.4 3.2 3.0 2.7 1.0 3.0 2.6 2.4 1.7 0.5 3.1 3.2 2.4 3.1 3.1 2.4 2.9 2.9 2.7 3.1 3.1 2.9 2.6 3.1 2.0 2.1 2.6 2.7 2.6 2.1 2.7 2.7 3.2 2.7 3.0 2.5 2.6 -0.1 3.0 0.0 3.0 1.1 1.7 2.2 2.4 -0.8 0.4 1.1 0.0
Depressed Affect (Nagel 2018) 0.5 1.1 3.6 -1.9 1.1 0.5 0.8 1.2 0.7 -1.5 0.9 0.8 -1.0 -0.1 -0.2 0.7 0.9 -0.2 0.6 0.8 1.0 1.2 1.3 0.0 0.7 1.2 1.0 1.2 0.8 -1.0 -0.2 1.0 1.1 0.1 0.4 1.1 0.9 1.2 0.1 1.2 0.3 -0.2 -1.7 -0.9 -1.9 1.0 -1.4 -1.0 -1.1 -0.7 -1.8 -1.9 -1.4 -1.4
Depression (Nagel 2018) 0.2 0.3 1.0 -0.6 0.7 0.5 0.4 0.8 0.4 -0.7 0.4 0.8 -0.3 0.9 0.8 0.2 0.7 -0.3 0.4 0.4 0.1 0.6 1.0 0.0 0.3 0.7 0.6 0.6 0.4 -0.8 0.6 0.5 0.8 0.3 0.4 0.8 0.6 0.5 0.4 0.7 0.5 0.2 -0.8 -0.4 -0.4 0.4 -0.2 -0.2 -0.2 -0.4 -0.7 -0.5 -0.4 -0.1
Intelligence (Savage-Jansen 2018) 0.8 2.6 8.2 1.0 -1.9 -1.9 -1.8 -1.9 -1.6 -0.1 -2.0 -2.5 0.0 -0.5 -1.6 -1.9 -1.7 -0.8 -1.6 -2.0 -1.9 -1.5 -1.9 -1.6 -1.9 -2.4 -2.0 -2.7 -2.0 0.3 -1.1 -2.9 -2.2 -1.2 -1.2 -2.2 -2.0 -2.2 -1.2 -1.9 -1.4 -1.1 0.9 -0.8 1.1 -1.9 0.3 -0.3 -0.2 -0.8 1.6 1.0 0.4 -0.1
Neuroticism (Nagel 2018) 0.3 0.8 3.3 -1.8 0.4 -0.1 0.2 0.6 0.3 -1.7 0.2 0.3 -1.5 -0.4 0.3 0.0 0.3 -0.7 -0.0 0.2 0.8 0.4 0.6 -0.6 0.1 0.6 0.3 0.6 0.2 -1.2 -0.7 0.5 0.4 -0.2 -0.2 0.4 0.3 0.5 -0.4 0.6 -0.3 -0.7 -1.6 -1.2 -1.8 0.6 -1.5 -1.4 -1.2 -0.8 -1.6 -1.8 -1.6 -1.3
Schizophrenia (2018) 4.0 8.3 22.0 -0.7 3.6 3.5 3.7 3.4 3.1 0.8 3.7 3.7 1.4 1.4 0.4 3.8 3.5 2.4 3.5 3.7 2.8 3.3 3.3 3.2 3.8 4.1 3.6 3.8 3.8 1.7 2.7 3.4 3.3 2.6 2.3 3.3 3.3 4.7 2.6 3.7 2.8 2.5 -1.2 3.2 0.0 3.1 0.3 1.4 1.9 2.2 -2.2 -0.7 0.3 0.0
Schizophrenia vs Biploar Disorder 1.1 1.5 5.5 -1.0 1.3 1.4 1.3 1.3 1.2 -0.4 1.5 1.7 -0.2 -0.7 -1.4 1.4 1.2 0.4 1.2 1.4 0.8 1.2 1.3 1.3 1.4 1.9 1.4 1.8 1.4 0.8 1.7 1.3 1.5 1.1 0.7 1.5 1.3 2.3 0.6 1.7 1.0 0.6 -1.5 0.8 0.0 1.1 -0.8 -0.2 0.2 0.3 -1.9 -1.1 -0.8 0.0
Worry (Nagel 2018) 0.2 0.3 3.6 -0.4 0.6 -0.1 0.4 0.7 0.6 -0.2 0.3 0.6 0.7 1.1 1.9 0.2 0.6 -0.0 0.5 0.3 1.2 0.7 0.8 0.3 0.2 0.5 0.5 0.1 0.3 0.6 -0.1 0.5 0.6 0.6 0.5 0.6 0.5 0.4 0.4 0.9 0.4 0.2 -0.2 -0.5 -0.7 0.9 -0.4 -0.1 -0.1 -0.0 -0.5 -0.4 -0.2 -0.1
Alzheimer’s Disease (in mother) 0.2 0.2 0.7 -0.5 0.3 0.3 0.4 0.4 0.6 -0.2 0.5 0.8 -0.6 -0.7 0.4 0.5 0.2 0.1 0.3 0.4 0.4 0.3 0.1 0.3 0.5 0.5 0.4 0.7 0.4 0.5 0.1 0.6 0.2 0.7 0.1 0.1 0.5 0.5 -0.1 0.6 0.2 -0.1 -0.1 -0.2 -0.8 0.4 -0.4 -0.3 -0.2 0.5 -0.5 -0.6 -0.3 -0.1
Alzheimer’s Disease (in father) 1.5 1.6 5.8 -0.7 -1.4 -1.5 -1.3 -1.6 -1.5 -0.3 -1.2 -1.1 0.1 -0.9 -0.8 -1.0 -1.5 -0.9 -1.3 -1.1 -1.9 -1.5 -1.8 -1.6 -1.1 -1.3 -1.4 -1.0 -1.2 -0.1 -0.8 -1.4 -1.5 -0.8 -2.4 -1.5 -1.4 -1.1 -1.6 -1.9 -1.7 -1.6 -0.7 -1.1 -0.7 -1.4 -1.0 -1.6 -1.1 -1.4 -0.3 -0.5 -1.2 -0.7
Alzheimer’s Disease (including proxy) 0.4 0.6 2.2 -0.9 -0.7 -0.8 -0.6 -0.7 -0.5 -0.5 -0.4 -0.1 -0.8 -1.5 -0.4 -0.3 -0.8 -0.6 -0.7 -0.5 -0.9 -0.6 -1.0 -0.9 -0.4 -0.4 -0.6 0.0 -0.5 0.0 -0.7 -0.3 -0.8 -0.2 -1.4 -0.8 -0.6 -0.3 -1.1 -0.8 -1.0 -0.9 -0.6 -0.8 -0.8 -0.6 -0.9 -1.2 -1.0 -0.5 -0.7 -0.9 -1.0 -0.7
Crohns Disease (2017) 1.1 2.4 7.0 0.9 1.4 1.4 1.6 1.7 1.8 1.4 1.6 1.3 2.4 1.9 1.2 1.7 1.4 1.9 1.7 1.6 0.7 1.6 1.2 1.6 1.6 1.1 1.5 0.3 1.6 1.7 1.4 0.8 1.3 1.5 1.3 1.3 1.5 0.7 1.8 1.4 1.6 1.8 1.9 2.0 0.8 2.0 1.6 1.6 1.8 2.6 1.0 1.1 1.8 1.9
Irritable Bowel Disease (IBD) 0.6 1.4 3.3 0.8 1.1 1.1 1.3 1.2 1.2 1.0 1.2 0.8 1.3 1.1 0.8 1.3 1.0 1.8 1.3 1.2 0.8 1.2 0.8 1.4 1.2 0.9 1.1 0.4 1.2 1.7 1.5 0.6 1.1 1.6 1.4 1.1 1.0 0.5 1.4 1.0 1.1 1.4 1.1 1.6 0.8 1.4 1.1 1.2 1.2 1.4 0.7 0.9 1.2 1.1
Ulcerative Colitis (UC) 0.1 0.1 0.9 0.2 0.2 0.1 0.3 0.1 0.1 -0.0 0.2 -0.0 -0.9 -0.4 0.1 0.4 0.2 0.9 0.3 0.3 0.4 0.2 0.0 0.3 0.3 0.2 0.1 0.4 0.3 0.9 0.8 0.1 0.3 0.9 0.6 0.3 0.1 -0.0 0.3 0.1 -0.0 0.2 -0.1 0.4 0.4 0.1 -0.1 0.1 0.1 -0.5 -0.0 0.3 -0.0 -0.2
Major Depression (MDD) 0.9 1.0 2.9 -0.2 1.3 1.7 1.1 1.4 1.4 -0.5 1.1 1.1 -0.2 -0.3 -0.1 1.0 1.2 0.1 1.1 1.2 1.5 1.6 1.4 1.0 1.1 1.2 1.2 1.2 1.2 -0.4 1.4 0.8 1.7 0.6 1.4 1.7 1.1 0.8 1.2 1.2 1.2 1.0 -0.7 0.4 0.0 1.1 0.1 0.1 0.4 0.2 -0.9 -0.2 -0.2 0.0
Reaction Time 3.2 6.1 9.6 1.5 2.8 2.3 2.9 2.4 2.3 1.9 2.9 2.5 2.7 2.7 1.4 3.0 2.9 2.3 2.9 3.0 2.2 2.8 2.7 3.1 3.0 2.2 2.9 1.8 2.9 1.8 2.2 2.8 2.7 2.9 2.7 2.6 2.3 1.4 3.0 2.7 3.1 3.0 1.6 2.6 1.6 2.3 2.0 2.7 2.4 1.8 0.8 1.6 2.2 1.7
Verbal and Numeric Reasoning (VNR) 0.8 1.8 6.9 0.5 -1.7 -1.6 -1.5 -1.6 -1.3 -0.4 -1.6 -2.1 -0.0 -0.7 -1.1 -1.4 -1.6 -0.6 -1.5 -1.5 -1.8 -1.2 -1.8 -1.3 -1.5 -2.0 -1.7 -1.9 -1.6 0.6 -0.6 -2.6 -1.8 -0.8 -1.1 -1.8 -1.9 -1.9 -1.3 -1.6 -1.4 -1.2 0.8 -0.6 0.6 -1.7 0.1 -0.5 -0.3 -0.5 1.4 0.7 0.1 -0.3
Breast Cancer 0.2 0.6 2.6 -1.6 0.0 -0.8 -0.1 0.0 -0.6 -0.7 -0.1 0.2 0.2 -0.8 -0.6 -0.2 0.0 -0.1 -0.1 -0.1 -1.1 -0.2 0.3 -0.1 -0.2 0.2 0.0 0.1 -0.1 -0.0 0.3 -0.3 0.0 0.0 -1.4 0.0 0.2 0.3 -0.6 -0.2 -0.4 -0.8 -1.3 -1.2 -1.6 -0.4 -1.2 -1.1 -1.3 -1.0 -1.5 -1.3 -1.3 -1.0
Ovarian Cancer 0.1 0.2 0.5 -0.5 -0.4 -0.7 -0.4 -0.5 -0.6 -0.5 -0.2 0.0 -0.7 -0.6 0.2 -0.3 -0.6 -0.2 -0.3 -0.3 -0.2 -0.2 -0.5 -0.5 -0.3 -0.1 -0.3 -0.1 -0.3 0.1 0.2 0.2 -0.2 0.1 -0.5 -0.2 -0.5 -0.1 -0.5 -0.1 -0.3 -0.4 -0.7 -0.2 -0.2 -0.2 -0.6 -0.6 -0.5 -0.6 -0.6 -0.5 -0.7 -0.5
Prostate Cancer 2.1 2.9 12.6 -3.3 0.5 1.2 0.4 0.6 0.2 -1.6 0.6 1.3 -3.2 -2.2 -3.4 0.5 0.4 0.7 0.3 0.5 1.0 0.3 0.6 0.1 0.5 1.6 0.5 2.6 0.5 -0.5 0.4 1.7 0.3 0.0 -1.0 0.3 0.9 2.6 -1.1 0.3 -0.8 -1.1 -2.8 -1.5 -3.5 0.6 -3.1 -2.2 -2.1 -0.6 -3.6 -3.4 -2.6 -2.2
Age at First Birth 0.4 0.5 2.8 1.0 -0.5 -0.3 -0.5 -0.4 -0.6 0.9 -0.6 -1.0 1.6 0.4 1.0 -0.6 -0.4 -0.2 -0.4 -0.6 -0.3 -0.5 -0.3 -0.4 -0.6 -0.8 -0.5 -0.9 -0.6 -0.3 -1.7 -0.1 -0.5 -0.6 -0.1 -0.4 -0.4 -0.9 0.1 -0.6 0.0 0.3 1.1 0.5 1.5 -0.5 1.0 0.9 0.5 0.4 1.4 1.1 1.0 0.4
Bipolar Disorder (2011) 0.4 0.4 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 -2.3 0.6 0.0 1.7 -1.1 -0.6 -0.1 -0.2 -2.5 -1.7 -1.4 0.0
Body Mass Index (BMI) (2010) 0.9 1.3 4.3 0.6 1.3 1.4 1.3 1.0 1.1 0.5 1.3 1.5 0.4 0.5 0.6 1.4 1.4 1.4 1.4 1.4 0.4 1.2 1.3 1.5 1.4 1.3 1.3 1.1 1.4 1.2 2.1 0.4 1.3 1.1 1.1 1.3 1.0 0.9 1.3 0.8 1.3 1.4 0.3 1.4 0.0 1.4 0.8 0.8 1.3 0.9 -0.0 0.5 0.6 0.0
Coronary Artery Disease (CAD) 0.1 0.1 1.1 -0.5 0.1 0.3 0.0 -0.2 -0.1 -0.7 0.2 0.3 -1.1 -0.8 -0.9 0.1 -0.1 -0.3 0.0 0.2 -0.1 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.2 -0.3 0.0 0.0 0.3 0.0 -0.2 0.3 -0.2 0.0 -0.2 0.1 0.0 -0.1 -0.5 -0.4 0.0 -0.1 -0.5 -0.4 -0.5 -0.6 -0.6 -0.5 -0.6 0.0
Crohns Disease (2012) 1.0 1.6 6.9 0.8 1.3 1.3 1.4 1.3 1.1 1.5 1.4 1.3 2.6 1.8 0.6 1.3 1.3 1.4 1.4 1.4 0.7 1.5 1.2 1.4 1.4 1.1 1.4 0.4 1.4 0.6 1.3 1.5 1.5 1.1 1.4 1.5 1.2 0.3 1.6 1.2 1.5 1.8 0.8 1.3 0.0 1.2 1.4 1.3 1.2 0.7 0.5 1.0 1.2 0.0
Mean Putamen Volume 1.5 1.7 4.6 0.5 -1.6 -1.6 -1.5 -1.4 -1.5 0.1 -1.6 -1.7 0.5 0.6 -1.1 -1.5 -1.3 -0.7 -1.4 -1.6 -1.1 -1.7 -1.5 -1.4 -1.6 -1.8 -1.6 -2.1 -1.7 -0.5 -1.6 -1.8 -1.9 -0.6 -1.2 -1.9 -1.5 -1.5 -1.1 -1.6 -1.3 -1.1 0.8 -0.6 0.3 -1.5 0.1 -0.2 -0.4 -0.3 1.2 0.6 0.4 -0.4
Fasting Glucose 4.5 5.4 9.4 1.2 2.4 2.6 2.6 2.8 2.8 1.9 2.5 2.5 1.6 2.3 1.1 2.5 2.2 2.9 2.5 2.5 2.3 2.5 2.1 2.4 2.5 2.3 2.4 1.8 2.5 1.8 2.6 2.4 2.5 2.3 2.3 2.5 2.8 2.4 2.6 2.5 2.7 2.5 1.3 2.5 1.0 2.7 2.1 2.3 2.6 3.1 0.5 1.1 2.1 2.6
HbA1C 1.0 1.2 4.5 1.6 0.6 0.5 0.9 0.5 0.8 2.1 0.8 0.6 1.1 1.2 0.9 0.9 0.3 0.7 0.7 0.9 1.4 1.0 0.1 0.5 0.8 0.5 0.6 0.1 0.9 0.8 0.8 0.7 1.0 0.3 1.5 1.0 0.6 0.4 1.3 0.8 1.2 1.6 1.4 1.0 1.2 1.0 1.8 1.7 1.6 1.3 1.2 1.4 1.8 1.6
HDL Cholesterol 1.3 2.2 5.0 -0.2 -1.8 -1.9 -1.7 -1.9 -1.7 -1.1 -1.6 -1.8 -1.6 -1.5 -1.8 -1.6 -1.8 -2.0 -1.8 -1.6 -1.2 -1.9 -2.0 -1.6 -1.6 -1.8 -1.8 -1.7 -1.6 -1.2 -2.2 -1.0 -1.8 -1.4 -1.2 -1.8 -1.9 -1.7 -1.7 -1.2 -1.7 -1.6 0.2 -1.3 0.0 -1.3 -0.7 -1.2 -1.0 -0.7 0.6 -0.2 -0.7 0.0
LDL Cholesterol 0.7 1.1 4.6 0.2 -1.3 -0.9 -1.2 -1.5 -1.6 -0.3 -1.2 -1.6 -0.0 -0.6 -1.3 -1.1 -1.2 -0.5 -1.2 -1.2 -1.1 -1.3 -1.3 -1.1 -1.2 -1.4 -1.2 -1.5 -1.2 -0.9 -0.5 -2.2 -1.3 -1.3 -1.1 -1.3 -1.5 -1.2 -0.9 -1.4 -1.1 -0.9 0.7 -0.5 0.0 -0.9 -0.3 -0.5 -0.3 0.0 0.7 0.4 -0.1 0.0
Lupus 0.9 1.3 4.4 1.5 -1.0 -1.3 -0.8 -0.8 -0.7 1.5 -1.1 -1.0 0.9 1.2 -1.0 -1.0 -0.7 -0.9 -0.8 -1.0 -1.5 -1.1 -1.0 -1.0 -1.0 -1.4 -1.1 -1.7 -1.0 -1.5 -0.8 -0.8 -1.2 -0.8 -0.8 -1.1 -0.5 -1.3 -0.0 -1.4 -0.5 0.1 1.7 1.1 2.1 -0.5 1.2 0.9 1.1 0.9 2.0 1.6 1.5 0.8
Neuroticism (2016) 0.3 0.5 5.7 -1.2 0.0 0.4 -0.1 0.1 -0.2 -1.9 0.0 0.2 -2.4 -1.1 -0.7 -0.1 -0.1 0.1 -0.2 -0.0 0.4 0.2 0.1 -0.1 -0.1 0.5 0.0 0.1 -0.0 -1.0 -0.8 0.4 0.1 -0.1 0.3 0.1 -0.1 0.5 -0.6 0.4 -0.3 -0.5 -1.0 -0.4 -0.7 0.4 -1.1 -1.1 -0.7 -0.3 -1.3 -1.0 -1.1 -0.6
Primary Biliary Cirrhosis 1.9 2.7 5.9 1.6 1.7 1.4 1.8 1.6 2.0 2.0 1.7 1.5 1.8 1.6 0.1 1.8 1.8 1.1 1.8 1.8 1.4 1.2 1.6 1.6 1.8 1.3 1.7 1.1 1.7 0.8 1.5 1.7 1.6 1.3 1.7 1.6 1.7 1.0 2.1 1.9 2.0 2.1 1.4 2.4 0.0 2.0 2.0 2.0 2.4 2.1 1.1 1.5 1.9 0.0
Rheumatoid Arthritis 0.8 1.1 2.7 -0.9 -1.2 -1.2 -1.3 -1.2 -1.2 -1.5 -1.1 -1.2 -0.9 -1.0 -1.1 -1.3 -1.4 -0.9 -1.2 -1.2 -0.7 -1.0 -1.1 -0.9 -1.2 -1.0 -1.1 -0.8 -1.1 -0.5 -0.8 -0.9 -0.7 -0.6 -0.8 -0.7 -1.4 -1.2 -1.4 -1.1 -1.2 -1.2 -0.7 -1.6 0.0 -1.0 -0.9 -1.3 -1.3 -1.2 -0.3 -0.8 -1.1 0.0
Schizophrenia (2014) 3.7 8.2 21.4 -1.4 3.6 3.6 3.7 3.5 2.8 0.1 3.7 3.6 1.0 0.8 -0.1 3.8 3.4 2.7 3.4 3.7 2.8 3.3 3.2 3.3 3.7 4.2 3.5 4.1 3.7 2.1 2.9 3.3 3.3 2.9 2.1 3.3 3.2 4.6 2.3 3.8 2.6 2.1 -2.0 2.6 0.0 3.1 -0.3 0.7 1.3 1.5 -2.8 -1.4 -0.4 0.0
Triglycerides 0.4 0.6 1.4 1.0 0.8 1.0 0.8 0.7 0.7 0.7 0.7 0.6 1.2 0.9 1.1 0.7 0.8 0.7 0.8 0.8 -0.1 0.8 0.8 0.7 0.7 0.5 0.8 0.4 0.8 -0.3 1.1 -0.1 0.8 0.2 0.8 0.8 0.6 0.3 1.2 0.5 1.0 1.2 0.7 1.0 0.0 0.7 1.1 1.2 1.1 0.8 0.6 1.0 1.1 0.0
Type 2 Diabetes (T2D) (2012) 1.3 1.5 3.2 0.6 1.4 1.8 1.3 1.4 1.7 1.6 1.3 1.1 1.5 1.1 1.4 1.1 1.4 0.6 1.4 1.3 1.3 1.6 1.6 1.3 1.2 1.3 1.4 1.4 1.3 0.1 0.5 1.4 1.7 0.8 1.7 1.7 1.5 1.0 1.6 1.4 1.4 1.5 -0.2 0.9 0.0 0.9 0.9 1.1 0.7 0.3 -0.4 0.4 0.6 0.0
Ulcerative Colitis 0.6 0.9 3.2 1.5 0.8 0.8 0.9 0.6 0.7 1.1 0.7 0.2 0.6 1.3 1.1 0.9 1.0 0.8 0.9 0.8 1.0 0.5 0.7 1.0 0.8 0.3 0.7 0.4 0.8 0.4 0.6 0.7 0.6 1.3 1.8 0.6 0.6 -0.1 1.3 0.8 0.8 1.2 1.2 1.4 0.0 1.0 1.3 1.1 1.4 1.0 1.2 1.4 1.2 0.0
Blood Eosinophil Count 2.4 18.6 33.6 -0.8 5.4 5.0 5.2 5.6 5.3 2.1 5.3 5.5 2.0 3.0 0.4 5.2 5.4 4.4 5.2 5.3 5.0 4.9 5.5 5.0 5.2 5.7 5.3 5.4 5.2 3.2 4.3 5.6 5.1 4.1 3.7 5.1 5.8 5.6 4.1 4.8 4.3 3.7 -0.2 3.5 -0.8 5.2 0.5 2.5 2.4 3.3 -2.0 -1.0 1.3 1.1
Blood Platelet Count 2.8 32.5 59.9 1.4 6.5 7.0 6.5 6.7 6.3 4.9 6.3 6.8 3.9 4.8 5.0 6.3 6.5 5.8 6.6 6.4 7.7 7.2 6.4 6.8 6.3 6.2 6.4 5.6 6.3 5.3 4.8 7.3 6.2 6.5 6.7 6.2 6.6 6.4 6.0 6.7 6.2 5.7 2.0 5.1 1.3 5.8 2.5 5.2 4.4 5.0 -0.4 1.2 3.8 3.0
Blood Red Count 0.1 0.7 10.4 0.9 -0.2 -0.4 -0.2 -0.2 -0.5 0.5 -0.4 -0.7 3.2 1.2 2.5 -0.4 -0.1 0.9 -0.1 -0.5 -1.0 -0.9 -0.1 -0.1 -0.4 -0.7 -0.3 -1.2 -0.4 1.5 -0.4 -0.9 -0.4 0.3 -0.5 -0.3 -0.3 -1.0 0.4 -0.8 0.1 0.2 0.0 0.5 1.5 -0.5 0.8 0.1 0.6 -0.6 0.7 1.1 0.2 0.9
Blood White Count 2.6 19.4 32.1 1.0 5.2 5.7 5.2 5.3 5.0 4.0 5.2 5.2 3.3 4.2 1.0 5.2 5.2 5.1 5.2 5.2 4.8 5.1 5.2 5.0 5.2 5.0 5.2 4.4 5.1 3.0 3.9 5.3 4.8 4.1 4.5 4.8 5.6 5.0 4.8 4.8 4.9 4.7 1.4 4.1 1.1 4.9 2.2 3.7 3.6 3.8 -0.4 0.9 2.8 2.8
Heel T-Score 2.0 15.6 58.8 0.4 4.6 4.5 4.4 4.5 4.4 3.1 4.4 5.4 3.1 2.4 7.7 4.2 4.5 2.4 4.4 4.5 4.9 4.7 4.7 4.1 4.3 4.7 4.5 5.5 4.5 2.7 4.2 4.1 4.7 4.2 4.0 4.7 4.8 4.4 4.0 5.2 4.2 3.8 0.5 2.2 -0.3 4.0 0.9 2.8 2.2 2.4 -1.3 0.1 1.5 1.4
BMI 0.3 1.5 9.6 -0.5 -1.3 -0.5 -1.3 -1.1 -1.3 -1.4 -1.4 -0.8 -0.1 -0.3 -0.1 -1.4 -1.3 -0.2 -1.2 -1.4 -2.5 -1.1 -1.1 -0.7 -1.4 -1.3 -1.3 -1.0 -1.4 0.9 1.2 -3.1 -1.2 -0.1 -1.5 -1.2 -1.1 -1.3 -1.1 -1.9 -1.3 -1.3 -0.9 -1.1 -0.2 -1.3 -0.4 -1.3 -1.1 -1.8 -0.0 -0.3 -1.1 -0.7
Height 0.1 2.7 12.6 2.6 -1.2 0.5 -1.0 -1.0 -0.8 1.0 -1.4 -1.7 2.0 2.5 -3.0 -1.4 -1.0 -0.2 -1.0 -1.4 -1.3 -1.6 -1.1 0.1 -1.4 -2.0 -1.3 -2.0 -1.4 1.1 0.4 -3.2 -1.4 0.9 0.2 -1.4 -1.3 -3.2 0.3 -1.5 -0.3 0.2 2.9 0.1 1.8 -0.0 2.1 1.1 1.3 0.3 3.5 2.6 2.1 1.1
Waist Hip Ratio (WHR) 9.7 43.5 95.8 -2.8 8.1 8.3 7.6 8.2 8.1 1.6 7.8 8.8 0.9 2.0 4.4 7.4 7.7 5.9 7.7 7.8 7.9 8.1 8.5 7.5 7.6 8.9 8.1 9.8 7.8 4.6 7.4 7.7 8.3 7.1 6.3 8.2 8.9 8.9 5.5 8.5 6.3 5.1 -2.3 3.6 -2.8 7.5 -0.7 2.3 2.0 4.0 -5.3 -3.2 -0.1 0.8
Systolic Blood Pressure 1.7 8.7 23.8 0.8 3.2 2.8 3.2 3.2 3.4 3.3 3.4 3.6 1.5 2.8 -0.8 3.3 3.0 3.2 3.4 3.4 1.9 4.0 3.0 2.5 3.3 3.3 3.3 3.1 3.4 2.3 2.2 4.9 3.4 1.6 2.0 3.4 3.5 3.8 3.1 3.1 3.4 3.2 0.6 4.2 2.1 2.4 2.2 3.4 2.8 3.1 -0.2 0.9 2.3 2.1
Smoking Status 0.2 0.6 2.9 -1.0 -0.3 0.1 -0.3 -0.6 -1.0 -0.3 -0.2 0.5 -1.0 -0.8 -0.6 -0.3 -0.5 -0.4 -0.4 -0.2 -0.5 0.1 -0.4 -0.3 -0.2 0.1 -0.3 0.7 -0.2 -1.5 0.7 -0.2 -0.1 -1.1 -0.7 -0.1 -0.2 0.3 -0.6 -0.6 -0.6 -0.6 -0.7 -1.7 -1.4 -0.5 -1.3 -0.9 -1.3 -1.6 -1.1 -1.0 -1.0 -1.3
Allergy or Eczema 0.4 1.1 3.3 -1.0 -1.0 -0.7 -0.9 -0.9 -0.9 -0.7 -0.9 -0.4 -0.9 -1.4 0.9 -0.8 -0.9 -1.0 -1.2 -1.0 -1.6 -1.5 -1.2 -1.1 -0.8 -0.8 -1.1 -0.5 -1.0 -1.8 -1.4 -0.9 -1.4 -1.1 -1.6 -1.4 -0.8 -0.4 -1.3 -1.1 -1.4 -1.5 -0.8 -0.6 -0.7 -0.7 -1.3 -1.5 -0.9 -0.8 -0.5 -0.8 -1.1 -1.1
Cardiovascular Disease 0.9 2.8 8.8 -1.3 1.9 1.8 1.8 1.9 1.4 0.7 2.0 2.4 1.3 1.1 -1.4 1.9 1.6 1.9 1.8 2.0 1.5 2.7 1.8 1.3 1.9 2.5 2.0 2.7 2.0 1.2 1.3 3.0 2.2 1.2 0.2 2.2 1.9 3.0 1.3 1.8 1.5 1.3 -1.4 1.1 -0.5 1.3 -0.1 1.1 0.1 0.1 -1.7 -1.0 0.0 -0.6
Hypothyroidism (self reported) 0.2 0.4 1.7 -0.4 0.8 0.2 0.9 0.6 0.8 -0.0 1.0 0.8 0.5 0.1 -0.5 1.1 0.9 0.5 0.9 1.0 0.1 0.5 0.7 0.9 1.0 0.7 0.9 0.2 0.9 0.2 0.0 0.7 0.6 1.3 0.0 0.6 0.7 0.4 0.5 0.4 0.6 0.4 -0.2 0.3 -0.3 0.6 0.0 0.3 0.1 -0.2 -0.2 -0.3 0.1 -0.4
Respiratory disease 1.1 2.4 4.5 -0.9 1.9 1.5 1.9 2.0 2.0 0.2 1.9 2.1 1.3 1.2 -0.2 2.0 1.9 2.0 1.9 1.9 1.2 1.6 1.8 1.8 1.9 2.0 1.8 2.1 1.9 1.1 2.1 1.7 1.6 1.7 0.8 1.6 2.1 1.9 1.0 1.4 1.3 0.9 -0.5 1.3 -0.7 2.1 0.1 0.3 0.8 1.7 -0.9 -0.9 0.1 0.8
Type 2 Diabetes (T2D) (2018) 0.8 1.5 4.7 0.7 1.4 2.2 1.4 1.5 1.4 1.4 1.3 1.4 0.8 1.0 -0.7 1.4 1.4 0.5 1.2 1.4 0.8 1.0 1.2 1.1 1.4 1.3 1.3 1.5 1.4 -0.7 0.3 0.8 1.2 1.0 1.5 1.2 1.8 1.2 1.5 1.2 1.2 1.4 0.3 1.7 0.6 1.7 1.0 1.0 1.4 1.5 0.2 0.5 0.9 1.4
Lung FEV1/FVC ratio 2.8 14.4 24.6 -0.1 -4.7 -5.0 -4.7 -4.3 -4.1 -1.9 -4.8 -4.2 -0.3 -2.1 4.6 -4.7 -4.6 -4.2 -4.5 -4.9 -3.8 -4.7 -4.6 -4.6 -4.8 -4.7 -4.8 -4.9 -4.8 -1.8 -3.8 -4.6 -4.8 -3.7 -3.8 -4.8 -4.6 -4.2 -3.7 -4.5 -4.0 -3.7 0.1 -3.0 0.0 -4.1 -1.1 -2.7 -2.2 -1.9 1.3 0.2 -1.3 -1.0
Lung FVC 3.4 17.2 31.0 1.1 4.8 3.8 4.8 4.6 4.8 3.0 4.8 4.4 3.2 3.0 1.6 4.7 4.6 3.9 4.9 4.9 4.6 5.6 4.6 4.8 4.8 4.8 4.8 4.1 4.9 4.2 5.5 4.5 5.0 4.7 4.4 5.0 4.5 4.7 4.5 4.9 4.8 4.7 1.7 3.9 1.2 4.3 1.8 4.2 3.2 3.9 -0.5 0.9 2.9 1.9
Neuroticism 0.7 1.6 4.4 -0.6 1.7 1.3 1.5 2.1 1.5 -0.5 1.4 1.5 -0.3 0.7 -0.3 1.2 1.6 0.8 1.3 1.4 1.9 1.8 2.0 1.0 1.3 1.6 1.6 1.2 1.4 0.0 0.3 1.8 1.9 1.2 1.6 1.9 1.6 1.3 1.3 2.0 1.3 0.9 -0.3 0.3 -0.7 1.8 -0.1 0.3 0.4 0.8 -0.8 -0.6 -0.0 0.1
Chronotype (morning person) 0.8 1.8 7.5 2.4 -1.1 -1.9 -0.9 -1.1 -1.0 1.6 -1.0 -1.1 1.0 0.8 1.7 -0.8 -0.9 -1.2 -0.9 -0.9 -0.8 -1.2 -1.3 -1.1 -0.9 -1.6 -1.0 -1.9 -1.0 -0.7 -0.9 -0.5 -1.2 -1.2 -0.3 -1.2 -1.2 -2.0 0.1 -1.2 -0.1 0.3 2.5 0.5 2.0 -0.7 1.8 1.4 1.2 0.8 2.7 2.3 2.0 1.3
Hair Pigment 0.9 24.5 40.2 -0.8 -6.0 -6.0 -6.0 -5.8 -5.5 -2.1 -6.0 -5.5 -3.3 -3.3 -0.9 -6.1 -5.9 -6.1 -5.9 -6.0 -5.2 -6.1 -5.8 -6.3 -6.0 -5.5 -6.0 -4.7 -6.0 -5.4 -5.8 -4.9 -5.8 -5.8 -5.6 -5.8 -5.7 -4.7 -5.1 -5.7 -5.6 -4.9 -1.0 -4.6 -1.0 -5.5 -2.4 -4.0 -3.8 -4.1 0.4 -0.7 -2.7 -2.4
Tanning 1.2 14.2 21.4 1.4 4.3 3.8 4.3 4.5 4.2 3.5 4.2 4.4 3.0 3.1 3.1 4.1 4.2 3.4 4.2 4.2 3.4 4.4 4.2 4.1 4.2 4.1 4.3 3.6 4.2 2.0 4.4 4.0 4.3 3.6 3.8 4.3 4.6 3.9 4.2 4.0 4.5 4.2 1.9 4.0 1.6 3.9 2.7 4.0 3.5 4.2 0.3 1.3 3.1 2.9
Hand grip strength (left) 1.3 3.4 7.2 0.7 2.2 2.2 2.1 2.1 2.1 0.8 2.1 2.3 1.1 1.7 -0.3 1.9 2.3 1.7 2.1 2.0 1.9 1.7 2.4 2.3 2.0 1.9 2.2 1.5 2.0 2.3 2.7 1.7 2.1 2.2 2.0 2.0 2.1 1.3 2.1 2.2 2.3 2.0 0.4 1.5 0.6 2.0 1.3 1.2 1.6 1.5 -0.2 0.7 0.9 2.0
Number of treatments/medications taken 0.1 0.2 1.6 0.0 -0.3 -0.4 -0.3 -0.2 -0.4 0.3 -0.3 -0.1 -0.7 -0.7 -1.3 -0.3 -0.5 -0.1 -0.3 -0.3 -0.1 0.3 -0.5 -0.5 -0.3 -0.2 -0.4 0.0 -0.2 -1.2 -0.6 0.5 -0.0 -0.4 -0.3 -0.0 -0.2 0.0 -0.0 -0.4 -0.2 0.1 -0.1 0.5 0.6 -0.1 0.1 -0.1 0.3 0.4 -0.0 0.2 -0.0 0.5
Average weekly spirits intake 3.0 3.7 6.2 1.0 2.2 1.3 2.2 2.1 2.2 1.8 2.2 2.5 1.6 1.9 2.4 2.1 2.1 0.5 2.1 2.2 2.3 2.1 2.1 1.9 2.2 1.9 2.2 2.0 2.2 0.2 1.8 2.3 2.3 1.5 2.5 2.3 2.4 1.5 2.2 2.4 2.3 2.3 1.1 1.7 0.7 2.2 1.3 1.8 1.8 1.8 0.3 0.8 1.5 1.6
Sensitivity / hurt feelings 2.5 4.3 11.7 -2.3 2.5 2.4 2.3 2.9 2.5 -0.9 2.3 2.5 -1.2 0.0 -1.4 2.2 2.4 1.5 2.1 2.4 2.1 1.8 2.6 1.9 2.3 3.0 2.4 3.4 2.4 0.1 1.8 2.5 2.4 2.0 0.7 2.4 2.8 3.1 1.0 2.2 1.2 0.7 -2.0 0.8 -2.1 2.8 -1.6 -0.9 -0.2 1.2 -2.9 -2.5 -1.5 -0.5
Frequency of depressed mood in last 2 weeks 0.2 0.3 1.2 0.5 0.7 1.1 0.5 0.9 0.3 0.4 0.4 0.5 -0.2 0.9 0.5 0.2 0.8 0.6 0.5 0.4 0.1 0.7 1.1 0.4 0.3 0.3 0.6 0.5 0.4 -0.3 0.2 0.8 0.7 0.4 0.8 0.7 0.9 0.1 0.9 0.7 0.8 0.7 0.2 0.4 0.7 0.3 0.7 0.6 0.5 0.2 0.2 0.5 0.4 0.5
Hearing difficulty/problems: Yes 0.3 0.5 2.7 -1.6 0.2 0.2 0.1 0.1 -0.0 -1.2 0.2 0.3 0.3 -0.6 -1.1 0.2 0.2 -0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.5 0.2 0.5 0.2 -0.3 -0.3 0.3 0.1 0.0 -0.6 0.1 -0.1 0.8 -0.6 0.2 -0.5 -0.7 -1.5 -0.5 -1.2 -0.1 -1.5 -1.2 -1.1 -0.8 -1.6 -1.5 -1.4 -1.1
Relative age of first facial hair 0.9 1.9 6.9 1.7 1.1 1.0 1.1 1.1 1.1 2.4 1.0 1.1 1.1 1.6 2.6 1.0 1.4 1.4 1.4 1.1 1.3 0.8 1.3 1.5 1.0 0.7 1.1 0.4 1.0 1.5 0.6 1.4 0.9 1.4 1.9 0.9 1.4 0.6 1.6 1.4 1.6 1.7 1.4 1.4 1.7 0.6 1.6 1.9 1.7 1.3 1.1 1.5 1.7 1.7
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 1.3 0.3 -0.7 -0.3 -0.6 -0.5 -0.6 0.3 -0.7 -0.9 0.5 0.4 -1.1 -0.5 -0.4 0.9 -0.6 -0.7 -0.8 -1.2 -0.7 -0.6 -0.6 -0.9 -0.7 -1.2 -0.7 0.0 -0.8 -1.1 -1.1 -0.1 -0.5 -1.1 -0.4 -0.8 -0.5 -1.0 -0.8 -0.7 0.2 0.3 0.4 -0.5 0.2 -0.6 0.2 0.0 0.6 0.4 -0.0 0.6
Ever used hormone-replacement therapy (HRT) 4.3 5.5 10.5 -1.0 -2.8 -2.9 -2.7 -2.9 -3.2 -1.4 -2.6 -2.6 -0.9 -2.2 -0.7 -2.5 -2.8 -1.6 -2.7 -2.6 -2.5 -2.4 -2.9 -2.6 -2.6 -2.5 -2.7 -2.2 -2.6 -1.5 -2.2 -2.2 -2.7 -2.4 -2.8 -2.7 -2.8 -2.1 -2.7 -3.0 -2.8 -2.6 -0.8 -2.3 -0.9 -2.8 -1.6 -2.0 -2.2 -2.5 -0.1 -0.9 -1.5 -2.2
Ever had hysterectomy (womb removed) 3.1 3.5 9.8 2.5 1.4 1.3 1.7 1.3 1.2 3.1 1.5 1.0 2.6 2.3 1.2 1.7 1.5 1.9 1.6 1.6 1.2 1.0 1.1 1.7 1.6 0.9 1.4 0.2 1.6 1.6 1.7 1.1 1.2 1.5 1.9 1.2 1.4 0.8 2.3 1.4 1.9 2.5 2.3 2.6 2.4 1.6 2.6 2.5 2.9 2.0 1.9 2.5 2.6 2.9
Systolic blood pressure, automated reading 1.1 3.2 7.9 0.7 1.7 2.0 1.8 1.9 1.9 2.1 1.9 2.1 0.8 1.5 0.3 1.9 1.5 1.9 1.9 1.9 0.7 2.7 1.5 1.4 1.8 1.9 1.8 2.2 1.9 1.6 1.8 2.7 2.2 1.0 1.3 2.2 1.9 2.4 1.9 1.8 2.0 2.0 0.4 2.8 1.6 1.3 1.2 1.8 1.9 2.3 -0.3 0.7 1.1 1.8
Eye problems/disorders: Diabetes related eye disease 2.4 2.7 6.5 0.1 2.0 2.5 2.0 2.0 2.3 0.9 2.0 1.8 0.9 1.4 1.0 2.0 2.0 1.4 2.0 2.0 1.8 1.6 2.0 1.7 2.0 2.0 2.0 2.6 2.0 0.8 1.7 1.6 1.8 1.9 1.3 1.8 2.2 1.7 1.6 1.8 1.7 1.5 0.4 1.2 -0.3 2.1 0.3 0.9 1.1 1.3 -0.5 -0.1 0.6 0.7
Angina 0.4 0.6 3.5 0.4 0.6 1.0 0.8 0.5 0.4 0.9 0.8 0.6 0.3 0.4 1.1 1.0 0.7 1.9 0.9 0.8 0.5 0.8 0.5 0.8 0.9 0.7 0.7 1.1 0.8 0.7 0.4 0.5 0.4 0.9 0.8 0.4 0.8 1.0 0.6 0.8 0.6 0.8 0.6 1.1 0.3 0.7 0.3 0.9 0.7 0.8 0.2 0.4 0.7 0.2
Medication for hormone replacement therapy 1.6 1.8 5.5 1.2 -1.5 -1.7 -1.6 -1.4 -1.2 0.3 -1.7 -1.7 -0.4 -0.2 1.6 -1.8 -1.4 -1.5 -1.6 -1.7 -1.2 -1.2 -1.3 -1.5 -1.8 -1.9 -1.6 -1.9 -1.7 -1.1 -2.3 -1.0 -1.4 -1.9 -0.6 -1.4 -1.5 -2.1 -0.6 -1.2 -0.9 -0.6 0.8 -0.5 1.2 -1.5 0.9 0.2 -0.1 -0.6 1.6 1.2 0.5 0.2
Vitamin and mineral supplements 0.5 0.7 3.3 1.3 0.3 0.7 0.4 0.4 0.4 0.8 0.2 0.3 0.5 0.6 -0.6 0.2 0.4 0.9 0.5 0.2 -0.5 0.0 0.4 0.3 0.2 -0.0 0.3 -0.5 0.2 1.0 -0.4 0.1 0.2 0.6 0.2 0.2 0.3 -0.1 1.1 0.4 0.8 1.1 1.5 0.9 1.0 0.8 1.4 1.1 1.4 1.6 1.3 1.5 1.4 1.8
Supplements: Zinc 0.2 0.2 1.9 0.5 -0.0 0.1 0.0 0.4 0.5 0.6 -0.0 0.3 -0.1 0.8 -0.2 -0.1 -0.0 -0.4 -0.2 -0.0 -0.5 0.3 -0.1 -0.1 -0.0 -0.0 -0.0 -0.1 -0.0 -0.9 -0.5 0.1 0.0 -0.3 0.1 0.0 0.4 0.4 0.1 0.1 0.2 0.1 0.8 0.8 0.7 -0.0 0.6 0.5 0.6 1.4 0.6 0.5 0.7 0.6
Medication: Co-codamol 0.6 0.7 3.0 1.3 -0.7 -0.6 -0.6 -0.9 -0.4 0.4 -0.7 -0.7 1.3 0.7 1.4 -0.7 -0.6 -0.4 -0.5 -0.7 -0.8 -0.6 -0.6 -0.6 -0.7 -1.2 -0.7 -1.2 -0.7 -0.1 -0.3 -1.3 -0.7 -0.4 -0.3 -0.7 -0.8 -1.7 0.0 -0.8 -0.1 0.1 1.1 -0.3 1.1 -0.8 1.1 0.6 0.4 -0.4 1.6 1.4 1.0 0.4
Medication: Metformin 1.7 2.4 5.0 0.6 1.8 2.1 1.9 1.9 2.2 1.0 1.8 1.7 1.3 1.3 -0.0 1.7 1.8 1.0 1.8 1.8 1.3 1.7 1.7 1.6 1.8 1.8 1.8 1.8 1.8 0.1 1.5 0.9 1.7 1.7 1.8 1.7 2.0 1.8 1.9 1.8 1.8 1.9 0.5 1.6 0.4 2.1 0.8 1.1 1.5 1.8 -0.3 0.4 0.9 1.5
Diabetes (father) 0.6 0.7 2.5 1.5 -0.7 -0.3 -0.7 -0.8 -0.9 0.4 -0.8 -0.5 1.3 0.0 0.1 -0.8 -0.5 -0.3 -0.5 -0.7 -1.4 -1.0 -0.5 -0.5 -0.7 -1.1 -0.7 -1.0 -0.7 -0.3 -0.9 -0.9 -0.7 -0.4 -0.2 -0.7 -0.9 -1.1 0.1 -0.9 -0.0 0.2 1.0 0.1 1.4 -1.0 1.5 0.8 0.7 0.3 1.4 1.6 1.1 1.4
Diabetes (mother) 0.7 0.9 1.6 0.8 1.1 1.0 1.0 1.0 0.7 1.3 1.0 0.9 0.8 0.9 -0.2 1.0 1.1 1.0 1.0 1.0 1.0 1.0 1.1 1.0 1.0 0.9 1.1 0.6 1.1 0.5 0.3 1.3 1.1 0.8 1.2 1.1 1.2 0.7 1.2 1.0 1.1 1.1 0.3 0.8 0.7 0.7 1.0 0.9 0.9 0.4 0.2 0.8 0.7 1.2
Severe depression (siblings) 0.3 0.3 1.7 -1.3 0.3 0.0 0.2 0.4 0.2 -0.6 0.2 0.3 -0.6 -0.3 0.7 0.2 0.2 0.6 0.2 0.2 -0.0 0.3 0.3 0.3 0.2 0.5 0.3 0.5 0.2 1.1 0.4 -0.0 0.2 0.4 -0.2 0.2 0.5 0.7 -0.3 0.4 -0.1 -0.4 -1.0 -0.3 -1.1 0.2 -1.1 -0.7 -0.8 -0.2 -1.2 -1.2 -0.9 -1.0
Pack years adult smoking proportion 2.5 3.8 6.8 0.7 2.3 2.2 2.3 2.2 2.5 1.2 2.4 2.4 1.0 1.2 0.5 2.3 2.2 1.5 2.3 2.4 1.5 2.3 2.2 1.8 2.4 2.1 2.4 2.1 2.4 0.5 2.4 2.2 2.4 1.7 2.1 2.4 2.5 1.5 2.3 2.6 2.4 2.3 1.0 1.8 0.7 2.4 1.5 1.9 1.8 1.8 0.4 0.7 1.5 1.3
Impedance of leg (right) 0.5 2.5 7.7 -0.5 1.8 1.8 1.9 1.9 2.3 0.5 1.9 1.4 1.9 1.5 -1.6 2.1 1.9 2.3 1.8 1.9 2.8 1.3 1.6 1.4 2.0 1.8 1.9 1.4 1.9 1.8 0.3 2.2 1.4 1.4 1.2 1.3 2.0 1.8 1.0 1.6 1.3 1.0 0.3 1.8 -0.5 2.2 -0.0 0.5 1.1 2.2 -0.5 -0.5 0.4 0.7
Leg fat-free mass (left) 1.0 5.2 18.1 0.4 -2.7 -1.7 -2.8 -2.6 -3.0 -1.5 -2.9 -2.5 -1.1 -1.0 -1.4 -3.0 -2.7 -1.8 -2.6 -3.0 -3.7 -2.6 -2.5 -1.9 -3.0 -2.9 -2.8 -2.6 -2.9 -0.7 -0.4 -4.3 -2.5 -1.2 -2.1 -2.5 -3.0 -3.3 -1.8 -2.9 -2.2 -1.9 -0.1 -2.6 0.1 -2.6 0.0 -1.4 -1.5 -2.6 1.2 0.5 -0.7 -0.7
Trunk fat percentage 0.2 0.6 7.2 -0.4 0.7 1.6 0.6 0.9 0.6 -0.5 0.5 0.5 0.8 0.4 -1.5 0.5 0.6 1.6 0.6 0.5 -0.2 0.9 0.7 0.9 0.4 0.6 0.6 0.9 0.5 2.7 1.9 -1.0 0.6 1.3 -0.0 0.6 0.5 0.6 0.5 -0.1 0.4 0.1 -0.2 -0.2 -0.5 0.4 -0.2 0.2 -0.1 -0.5 -0.3 -0.3 -0.1 -0.6
Hand grip strength (right) 1.0 2.6 5.3 1.6 1.6 1.9 1.5 1.7 1.6 1.6 1.5 1.9 1.1 1.9 1.4 1.3 1.8 1.2 1.6 1.4 1.1 1.3 1.9 1.9 1.4 1.2 1.7 0.9 1.4 1.5 2.0 1.1 1.6 1.8 1.8 1.5 1.7 0.8 2.0 1.7 2.1 2.0 1.4 1.6 1.4 1.6 1.9 1.8 2.0 1.8 0.9 1.6 1.7 2.3
Townsend deprivation index at recruitment 2.2 3.0 6.9 -0.2 2.1 2.4 2.0 2.1 1.8 0.2 2.0 2.1 -0.4 0.4 -0.2 1.9 2.1 2.2 2.1 2.0 1.8 2.4 2.2 2.2 1.9 2.1 2.0 2.2 2.0 2.6 2.2 1.8 2.2 2.2 1.6 2.2 2.0 1.7 1.9 2.1 1.8 1.7 -0.1 1.4 0.1 2.2 0.5 1.0 1.0 0.9 -0.6 -0.0 0.4 0.6
Current tobacco smoking 1.3 2.2 6.9 0.7 1.6 2.4 1.6 1.3 1.1 1.4 1.8 2.3 0.6 0.7 0.5 1.6 1.4 0.8 1.4 1.7 1.2 2.0 1.5 1.4 1.7 1.8 1.7 2.2 1.8 -1.2 2.6 1.1 2.0 0.0 1.6 1.9 1.6 1.7 1.7 1.3 1.8 1.9 1.1 0.7 0.2 1.8 0.5 1.5 1.1 0.9 -0.1 0.6 1.1 0.6
Average weekly fortified wine intake 1.6 1.9 4.4 0.0 1.5 1.3 1.6 1.4 1.6 0.4 1.6 1.5 -0.0 -0.0 0.3 1.8 1.4 2.1 1.7 1.7 2.0 1.6 1.3 1.7 1.7 1.4 1.5 1.6 1.7 2.1 2.1 1.7 1.5 2.1 1.3 1.5 1.5 1.0 1.2 1.5 1.3 1.2 0.3 1.3 -0.1 1.8 0.5 0.6 1.1 1.5 -0.2 0.1 0.5 1.1
Maternal smoking around birth 0.2 0.3 3.4 -0.6 0.2 0.1 0.2 0.0 -0.1 -0.2 0.3 0.3 -1.6 -1.0 -1.9 0.4 0.2 -0.2 0.1 0.3 -0.7 -0.6 0.0 -0.0 0.3 0.1 0.2 0.3 0.2 -1.1 -0.5 0.5 -0.1 0.2 -0.4 -0.1 0.3 -0.1 -0.2 -0.3 -0.2 -0.2 -0.2 -0.4 -0.8 0.3 -0.6 -0.5 -0.3 -0.3 -0.3 -0.5 -0.5 -0.6
Fed-up feelings 0.4 0.8 2.3 -0.5 1.2 1.5 1.0 1.2 1.1 -0.2 1.0 1.0 0.5 0.8 1.1 1.0 1.2 0.6 0.8 1.1 1.1 1.2 1.4 0.7 1.0 1.0 1.1 1.1 1.1 -0.3 -0.1 1.3 1.2 0.5 1.4 1.3 1.1 0.7 0.7 1.5 0.8 0.5 -0.3 0.1 -0.5 1.0 -0.1 0.0 0.1 0.1 -0.5 -0.4 -0.2 -0.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.5 1.7 -0.6 1.0 1.2 0.7 1.0 0.8 -0.9 0.7 0.8 -0.8 0.0 0.1 0.5 1.1 0.5 0.7 0.6 0.6 0.7 1.3 0.5 0.6 0.9 0.9 1.0 0.7 0.2 0.4 0.9 0.8 0.5 0.6 0.8 0.7 0.8 0.5 1.0 0.5 0.3 -0.7 -0.1 -0.5 0.6 -0.5 -0.1 -0.2 -0.3 -0.9 -0.6 -0.5 -0.5
Relative age voice broke 0.3 0.5 6.4 1.1 -0.4 -0.7 -0.5 -0.2 -0.4 1.1 -0.7 -0.2 0.1 0.5 2.5 -0.6 -0.1 0.0 -0.3 -0.6 -0.2 -0.7 -0.1 -0.3 -0.6 -0.8 -0.5 -1.1 -0.6 1.1 -0.6 -0.0 -0.6 -0.2 0.3 -0.6 -0.1 -0.6 0.2 -0.1 -0.0 0.1 0.9 0.2 1.0 -0.5 0.7 0.7 0.6 0.4 1.1 1.0 0.8 0.7
Taking other prescription medications 0.5 0.8 2.9 0.6 0.8 0.5 0.9 1.1 0.8 1.4 0.8 0.8 0.7 0.9 -0.1 0.9 0.8 0.7 0.8 0.9 0.5 0.6 0.7 0.4 0.9 0.7 0.8 0.6 0.9 -0.8 0.6 1.0 0.7 0.6 0.5 0.8 1.0 0.5 1.0 0.5 0.9 1.0 1.0 1.6 0.8 1.2 0.9 0.9 1.3 1.7 0.6 0.7 1.1 1.3
Age when periods started (menarche) 0.1 0.3 0.8 0.2 -0.7 -0.9 -0.6 -0.7 -0.7 0.3 -0.6 -0.8 -0.4 -0.7 -0.5 -0.5 -0.7 -0.1 -0.6 -0.6 -0.8 -0.6 -0.9 -0.8 -0.5 -0.6 -0.7 -0.9 -0.6 -0.4 -0.4 -0.5 -0.8 -0.7 -0.6 -0.8 -0.6 -0.3 -0.5 -0.7 -0.5 -0.4 0.5 -0.1 0.2 -0.5 -0.1 0.1 -0.1 -0.1 0.4 0.3 0.3 -0.3
Bilateral oophorectomy (both ovaries removed) 1.5 1.7 4.9 1.4 1.2 0.9 1.3 1.1 1.1 1.6 1.2 0.8 1.9 1.6 -0.8 1.3 1.4 1.7 1.3 1.2 0.1 0.5 1.2 1.5 1.3 0.8 1.2 0.3 1.2 1.7 1.7 0.8 0.9 1.2 1.0 0.9 1.1 0.6 1.6 0.9 1.5 1.7 1.0 1.6 1.5 1.3 1.8 1.5 2.0 1.3 1.0 1.5 1.5 2.2
Heel bone mineral density (BMD) T-score, automated (left) 1.0 2.2 4.6 0.8 1.6 2.0 1.5 1.5 1.2 1.6 1.5 2.0 0.1 0.2 1.3 1.3 1.5 1.6 1.6 1.6 1.6 2.0 1.8 1.5 1.4 1.7 1.6 2.1 1.6 1.2 2.0 1.6 2.0 1.4 2.0 2.0 1.8 1.5 1.7 2.1 1.8 1.7 0.8 0.6 0.2 1.3 0.6 1.5 1.0 0.8 -0.1 0.7 1.0 0.7
Tinnitus: Yes, but not now, but have in the past 0.9 1.0 2.8 -1.3 -0.9 -0.8 -0.9 -1.0 -1.1 -1.7 -0.8 -0.5 -0.4 -1.5 -1.1 -0.8 -1.0 -0.7 -1.0 -0.8 -0.7 -0.7 -1.1 -1.0 -0.8 -0.6 -0.9 -0.6 -0.8 -0.6 -0.4 -0.8 -0.9 -1.1 -1.6 -0.9 -1.1 -0.4 -1.4 -1.0 -1.1 -1.3 -0.7 -1.4 -1.4 -0.7 -1.3 -1.2 -1.3 -0.8 -0.6 -1.1 -1.0 -1.3
Qualifications: CSEs or equivalent 1.1 1.4 5.5 -2.1 1.0 0.9 0.9 1.1 1.1 -1.3 1.0 1.3 -1.7 -1.0 -0.8 1.0 0.9 0.1 0.7 0.9 0.2 0.2 0.9 0.6 1.0 1.5 0.9 2.1 0.9 -0.4 0.4 1.1 0.7 0.5 -0.4 0.6 1.1 2.1 -0.3 1.2 -0.1 -0.6 -2.0 -0.2 -1.9 0.9 -1.8 -1.4 -0.9 -0.2 -2.4 -2.2 -1.8 -1.1
Serious illness, injury or assault to yourself 0.3 0.4 1.3 0.6 -0.6 -0.2 -0.4 -0.7 -0.6 -0.1 -0.5 -0.7 -0.1 -0.0 -0.2 -0.3 -0.4 0.4 -0.4 -0.5 -0.9 -0.9 -0.7 -0.4 -0.4 -0.9 -0.6 -0.7 -0.6 0.6 -1.2 -0.9 -1.1 -0.0 -1.0 -1.1 -0.4 -1.1 -0.4 -0.9 -0.6 -0.4 0.3 0.3 0.7 -0.6 0.4 -0.2 0.2 -0.4 0.8 0.6 0.2 0.3
High blood pressure 0.1 0.3 3.2 -0.7 0.2 0.6 0.1 0.3 -0.3 0.2 0.3 0.4 0.3 -0.1 -1.8 0.2 -0.1 1.8 0.3 0.3 -0.0 1.4 0.1 -0.2 0.2 0.6 0.2 0.9 0.3 0.5 -0.1 1.1 0.6 0.2 -0.7 0.7 0.2 1.0 0.2 0.1 0.2 0.3 -0.6 0.2 -0.1 -0.0 -0.4 0.1 -0.3 0.0 -0.9 -0.4 -0.3 -0.2
Hayfever, allergic rhinitis or eczema 0.3 0.6 2.1 -0.5 -0.7 -0.7 -0.6 -0.6 -0.5 -0.1 -0.7 -0.5 -0.6 -1.1 0.4 -0.5 -0.5 -0.9 -0.8 -0.7 -1.4 -1.4 -0.8 -0.8 -0.6 -0.7 -0.8 -0.5 -0.7 -1.4 -1.3 -0.8 -1.3 -0.7 -1.4 -1.3 -0.5 -0.4 -0.9 -0.9 -1.0 -1.1 -0.4 0.1 -0.1 -0.5 -0.7 -0.9 -0.4 -0.3 -0.1 -0.4 -0.6 -0.6
Multivitamins +/- minerals 0.3 0.4 1.6 -0.7 -0.2 -0.5 -0.2 -0.3 -0.3 -0.4 -0.2 -0.3 -0.6 -0.5 0.9 -0.3 -0.3 -1.0 -0.4 -0.2 0.6 0.0 -0.2 -0.0 -0.2 0.1 -0.2 0.4 -0.2 -0.9 0.4 0.1 -0.0 -0.1 0.3 -0.0 -0.1 0.1 -0.6 -0.1 -0.5 -0.7 -1.0 -0.8 -0.8 -0.7 -1.1 -0.6 -1.1 -1.2 -1.0 -0.9 -1.0 -1.3
Stomach or abdominal pain in last month 1.9 2.4 6.0 -0.1 -1.6 -1.7 -1.6 -1.5 -1.7 -0.9 -1.8 -1.8 -0.9 -0.4 -0.4 -1.7 -1.4 -1.9 -1.7 -1.8 -2.0 -2.2 -1.5 -1.8 -1.7 -1.9 -1.7 -2.1 -1.8 -1.7 -2.5 -2.2 -2.0 -2.1 -1.7 -2.0 -1.6 -2.0 -1.5 -1.8 -1.5 -1.6 -0.2 -0.9 0.3 -1.5 -0.3 -1.1 -0.6 -0.9 0.7 0.1 -0.5 -0.4
Supplements: Glucosamine 2.1 2.7 8.2 -1.3 -1.5 -1.8 -1.4 -1.8 -2.1 -1.1 -1.4 -1.6 -1.6 -1.1 -2.9 -1.2 -1.6 -0.4 -1.5 -1.4 -1.5 -2.0 -1.7 -1.6 -1.3 -1.2 -1.5 -0.6 -1.4 -1.5 -0.9 -1.8 -1.7 -1.4 -2.2 -1.7 -1.6 -0.8 -1.9 -2.2 -2.0 -1.8 -1.8 -1.6 -1.0 -1.6 -1.7 -2.0 -1.8 -2.5 -1.0 -1.4 -1.9 -2.0
Diverticular disease/diverticulitis (self-reported) 2.0 2.4 4.6 -0.7 -1.7 -1.8 -1.7 -1.6 -1.7 -1.7 -1.8 -2.1 0.2 -0.4 -0.9 -1.7 -1.7 -0.2 -1.6 -1.8 -1.8 -1.9 -1.7 -1.2 -1.7 -1.8 -1.7 -2.1 -1.8 0.6 -1.6 -2.1 -1.9 -0.6 -1.8 -1.9 -1.8 -2.1 -1.6 -1.7 -1.8 -1.9 -0.5 -1.5 -0.6 -1.8 -0.9 -1.4 -1.5 -1.9 0.2 -0.4 -1.0 -1.4
Medication: Atenolol 0.4 0.5 3.7 -0.3 0.6 0.7 0.7 0.7 0.8 -0.2 0.7 0.9 -0.7 -0.2 -0.4 0.8 0.6 0.9 0.8 0.8 0.2 1.0 0.5 0.7 0.7 0.8 0.6 1.1 0.7 1.9 0.4 0.7 0.6 1.0 0.0 0.6 0.7 1.0 0.5 0.7 0.3 0.5 -0.2 0.9 -0.1 0.7 -0.1 0.0 0.3 0.8 -0.5 -0.2 -0.1 0.4
Medication: Levothyroxine sodium 0.4 0.7 2.6 -1.6 -0.2 -0.4 -0.1 -0.4 -0.4 -1.3 0.0 0.1 -1.1 -1.5 -0.9 0.1 -0.2 0.0 -0.2 0.0 -0.5 -0.1 -0.3 -0.2 0.1 0.2 -0.1 -0.2 -0.0 -0.1 -0.6 -0.4 -0.2 0.6 -1.1 -0.2 -0.3 0.4 -0.9 -0.6 -0.8 -0.9 -1.3 -0.8 -1.5 -0.1 -1.6 -1.2 -1.2 -1.2 -1.3 -1.5 -1.4 -1.6
Sitting height 2.1 15.0 51.0 1.0 -4.5 -3.6 -4.4 -4.4 -4.3 -2.0 -4.6 -5.5 -1.1 -1.4 -7.1 -4.5 -4.3 -2.6 -4.3 -4.6 -5.4 -4.8 -4.5 -3.8 -4.5 -5.1 -4.6 -5.5 -4.6 -1.6 -3.3 -5.9 -4.7 -2.8 -3.8 -4.7 -4.8 -5.7 -3.2 -5.2 -3.7 -3.2 0.9 -2.6 1.0 -3.4 0.4 -2.1 -1.3 -2.8 3.0 1.3 -0.3 -0.7
Chronic bronchitis/emphysema (father) 1.7 2.0 5.0 -0.3 1.8 1.9 1.7 1.7 1.5 0.5 1.7 1.7 -0.5 1.3 0.4 1.7 1.9 1.9 1.8 1.6 1.3 1.6 1.9 1.7 1.6 1.8 1.7 1.9 1.6 1.7 2.1 0.9 1.5 1.5 1.4 1.5 1.8 2.2 1.4 1.4 1.3 1.2 -0.5 0.8 -0.4 1.4 -0.2 0.5 0.5 0.5 -1.2 -0.3 0.0 0.4
High blood pressure (mother) 0.3 0.4 1.8 -1.1 0.2 -0.3 0.0 0.1 -0.2 -0.5 0.2 0.4 -1.1 -0.6 -0.7 0.0 0.0 0.6 0.1 0.2 0.0 0.6 0.3 0.1 0.1 0.5 0.2 0.4 0.2 0.1 0.3 1.0 0.5 0.4 -0.5 0.5 0.1 0.6 -0.2 0.4 -0.1 -0.2 -1.1 -1.3 -1.3 -0.1 -0.8 -0.6 -1.0 -1.1 -1.2 -1.0 -1.0 -0.8
Body mass index (BMI) 0.2 1.0 5.4 -0.5 -1.0 -0.3 -1.0 -0.9 -1.2 -1.2 -1.1 -0.6 -0.8 -0.8 -0.1 -1.1 -1.0 0.1 -0.9 -1.1 -2.1 -0.6 -0.8 -0.6 -1.2 -0.8 -1.0 -0.5 -1.1 1.1 1.2 -2.3 -0.8 0.0 -1.4 -0.8 -1.1 -0.6 -0.8 -1.5 -0.9 -1.0 -1.0 -1.3 -0.4 -1.4 -0.4 -0.9 -1.1 -1.7 -0.4 -0.3 -0.9 -0.5
Impedance of leg (left) 0.4 2.2 5.9 0.1 1.6 1.4 1.7 1.8 2.1 1.1 1.7 1.1 2.4 1.7 -1.1 1.8 1.7 1.9 1.7 1.6 2.3 1.3 1.5 1.2 1.8 1.5 1.6 1.0 1.6 1.8 0.2 2.2 1.2 1.3 1.2 1.2 1.7 1.6 1.2 1.4 1.3 1.2 0.9 2.0 0.2 1.9 0.3 1.1 1.3 2.1 0.1 0.1 1.0 0.6
Leg predicted mass (left) 1.0 5.5 18.6 0.4 -2.8 -1.8 -2.8 -2.7 -3.1 -1.5 -3.0 -2.6 -1.1 -1.0 -1.3 -3.1 -2.8 -1.9 -2.7 -3.1 -3.7 -2.7 -2.5 -1.9 -3.1 -3.0 -2.9 -2.7 -3.0 -0.7 -0.6 -4.3 -2.6 -1.3 -2.1 -2.6 -3.0 -3.4 -1.8 -2.9 -2.2 -2.0 -0.1 -2.7 0.1 -2.7 0.1 -1.4 -1.5 -2.7 1.3 0.6 -0.6 -0.7
Trunk fat mass 0.2 0.7 5.8 -0.1 -0.6 0.5 -0.6 -0.3 -0.6 -1.0 -0.8 -0.7 0.3 0.1 -1.7 -0.8 -0.6 0.7 -0.5 -0.8 -1.5 -0.3 -0.4 -0.1 -0.9 -0.7 -0.7 -0.4 -0.8 2.2 1.3 -2.4 -0.6 0.7 -0.9 -0.6 -0.8 -0.8 -0.3 -1.2 -0.6 -0.6 -0.1 -1.0 -0.3 -0.7 -0.1 -0.4 -0.6 -1.2 0.3 0.0 -0.3 -0.6
Waist circumference 0.3 1.0 7.9 -0.3 0.9 1.7 0.8 1.2 1.1 -0.5 0.7 0.9 0.2 0.4 0.4 0.6 0.9 1.7 1.1 0.7 0.1 1.2 1.2 1.3 0.5 0.9 0.8 1.4 0.7 2.6 2.8 -0.9 1.0 2.4 0.5 1.0 0.9 0.8 0.9 0.5 0.8 0.6 -0.4 0.0 -0.4 0.7 0.1 0.1 0.1 0.1 -0.6 -0.2 -0.1 0.4
Number of incorrect matches in round 0.8 1.4 5.0 1.1 1.1 1.4 1.2 0.8 0.9 1.5 1.2 1.1 0.8 1.6 2.2 1.4 1.1 1.7 1.2 1.3 1.0 1.2 0.8 1.0 1.3 0.9 1.1 1.0 1.3 0.4 1.1 1.1 1.0 1.1 1.1 1.0 1.0 0.7 1.3 1.0 1.3 1.5 1.3 1.1 0.8 1.0 1.0 1.5 1.2 0.9 0.7 1.0 1.4 0.9
Past tobacco smoking 0.6 1.0 2.7 0.2 1.2 1.0 1.1 1.2 1.6 -0.0 1.2 1.1 0.2 0.5 0.8 1.1 1.3 0.8 1.2 1.2 1.6 1.1 1.4 1.0 1.2 1.2 1.3 1.1 1.2 0.8 1.0 0.9 1.1 1.1 1.2 1.1 1.2 1.1 0.9 1.4 1.1 1.0 0.1 1.2 0.2 1.3 0.3 0.8 0.8 1.2 -0.2 0.1 0.5 0.4
Alcohol usually taken with meals 0.7 1.2 4.7 0.7 -1.4 -2.2 -1.3 -1.2 -0.9 0.1 -1.4 -1.9 -0.5 -0.4 0.8 -1.3 -1.4 -0.2 -1.1 -1.3 -0.4 -0.9 -1.4 -1.1 -1.4 -1.6 -1.4 -1.7 -1.4 0.5 -1.2 -2.1 -1.3 -0.4 -0.8 -1.3 -1.1 -1.5 -0.9 -1.1 -0.9 -0.8 0.8 -0.6 0.4 -1.1 0.2 0.0 -0.2 -0.0 1.2 0.6 0.4 -0.3
Nervous feelings 0.3 0.5 1.8 -0.2 0.8 0.9 0.8 1.0 0.9 0.4 0.7 0.8 -0.1 0.7 0.2 0.7 0.7 1.0 0.7 0.7 1.3 0.4 0.7 0.8 0.7 0.7 0.7 0.7 0.7 0.9 -0.2 1.3 0.6 1.3 1.1 0.6 1.1 0.5 0.5 1.2 0.5 0.4 -0.1 0.2 -0.5 1.2 0.0 -0.2 0.4 0.7 -0.3 -0.3 -0.1 0.6
Frequency of tenseness / restlessness in last 2 weeks 0.6 1.0 3.0 -1.4 0.9 1.4 0.7 1.0 0.7 -1.5 0.8 1.2 -1.7 -1.1 -1.6 0.6 0.8 0.7 0.7 0.8 0.6 0.9 1.1 0.7 0.7 1.1 0.9 1.5 0.8 0.7 0.5 1.1 1.1 0.9 0.5 1.1 0.8 0.9 0.3 1.0 0.3 0.0 -1.5 -0.5 -1.3 0.9 -1.1 -0.8 -0.8 -0.8 -1.6 -1.4 -1.3 -0.9
Hearing difficulty/problems with background noise 0.2 0.3 1.6 0.5 0.3 0.0 0.5 0.1 0.1 1.1 0.5 0.5 1.3 1.1 0.6 0.6 0.4 0.2 0.4 0.5 0.4 0.2 0.0 0.2 0.6 0.3 0.3 -0.2 0.4 -0.2 -0.5 0.9 -0.0 0.2 0.2 -0.0 0.2 0.3 0.4 0.3 0.2 0.6 0.6 1.0 1.0 0.4 0.3 0.6 0.7 0.1 0.5 0.6 0.6 0.1
Hair/balding pattern: Pattern 2 1.0 1.3 6.4 2.3 -0.1 -0.5 0.1 0.3 0.7 1.9 -0.1 -0.5 0.4 1.0 0.9 0.0 0.0 -0.5 -0.0 -0.0 -0.3 -0.4 -0.3 -0.2 -0.0 -0.6 -0.1 -0.6 -0.1 -0.6 -0.4 -0.4 -0.3 -0.4 0.5 -0.3 0.1 -0.9 1.0 0.0 0.5 1.0 2.5 1.8 2.3 0.6 2.1 1.6 1.9 1.7 2.5 2.3 2.1 1.8
Had menopause 0.2 0.2 1.7 -0.0 -0.6 -0.6 -0.5 -0.8 -0.7 -0.6 -0.5 -0.6 -1.3 -0.6 0.7 -0.4 -0.7 0.6 -0.3 -0.4 0.4 0.2 -0.7 -0.5 -0.4 -0.3 -0.6 -0.4 -0.4 0.5 -0.5 -0.2 -0.3 0.1 -0.0 -0.3 -1.0 -0.3 -0.4 -0.7 -0.5 -0.1 0.4 -0.1 -0.0 0.1 -0.5 -0.0 -0.0 0.1 0.1 -0.1 0.1 -0.5
Had other major operations 1.2 1.4 3.1 1.4 -1.5 -1.1 -1.2 -1.4 -1.7 1.0 -1.3 -1.4 0.2 0.1 0.2 -1.2 -1.5 -0.2 -1.1 -1.3 -1.7 -1.5 -1.6 -0.8 -1.2 -1.6 -1.4 -1.7 -1.3 -0.7 -1.5 -1.2 -1.3 -1.1 -0.5 -1.3 -1.1 -1.8 -0.3 -1.3 -0.7 0.0 1.6 -0.1 1.3 -0.8 1.2 0.3 0.5 0.4 1.7 1.4 1.1 1.2
Forced vital capacity (FVC) 0.3 1.3 4.6 1.2 0.9 0.8 0.9 1.0 0.8 1.0 0.8 0.5 2.1 1.3 -1.3 0.7 1.0 1.2 1.0 0.8 0.5 1.1 1.0 1.4 0.8 0.7 0.9 0.1 0.8 2.1 1.7 0.2 0.9 1.7 1.1 0.9 0.5 0.4 1.4 0.8 1.3 1.4 1.6 1.2 1.2 1.0 1.1 1.8 1.3 1.1 1.1 1.2 1.6 0.6
Heel bone mineral density (BMD) T-score, automated (right) 1.0 2.4 5.1 1.4 1.5 1.6 1.4 1.3 1.2 2.2 1.5 2.0 0.4 0.4 2.0 1.4 1.4 1.5 1.6 1.6 1.4 2.0 1.5 1.5 1.4 1.3 1.6 1.7 1.6 0.8 1.5 1.9 2.0 1.6 2.3 2.0 1.5 0.8 1.9 2.1 1.9 2.0 1.4 0.9 0.9 1.1 1.3 2.0 1.4 0.9 0.6 1.3 1.6 1.1
Ever unenthusiastic/disinterested for a whole week 0.3 0.3 1.8 0.4 0.5 1.2 0.6 0.5 0.3 0.6 0.6 1.1 0.7 0.9 1.3 0.6 0.6 0.9 0.6 0.5 0.7 0.2 0.4 0.4 0.6 0.5 0.5 0.5 0.5 -0.0 -0.1 0.6 0.1 0.7 0.6 0.1 0.7 0.6 0.6 0.7 0.4 0.5 0.2 0.7 0.4 0.4 0.4 0.4 0.4 -0.0 0.1 0.2 0.4 0.1
Qualifications: None of the above 0.6 1.2 5.5 2.2 0.1 -0.4 0.1 -0.2 -0.1 1.9 0.1 0.1 0.0 1.3 2.3 0.1 0.2 0.1 0.3 0.2 0.1 0.4 0.0 -0.0 0.1 -0.3 0.1 -0.7 0.2 -0.8 -0.2 0.9 0.2 -0.2 1.1 0.2 -0.0 -0.5 1.1 -0.3 0.8 1.4 2.1 1.4 2.4 0.1 1.8 2.1 1.7 1.0 2.0 2.2 2.2 1.4
Financial difficulties in last 2 years 4.4 6.0 13.6 -1.7 3.2 3.4 3.0 2.9 2.3 -0.3 3.1 3.5 0.3 0.9 0.1 3.0 3.0 3.0 2.9 3.0 2.0 2.7 3.3 2.8 3.0 3.4 3.2 3.7 3.1 1.8 2.9 3.0 3.1 2.3 1.4 3.0 3.3 3.0 1.8 2.7 2.2 1.5 -1.7 1.0 -1.4 2.5 -1.0 0.2 0.1 0.0 -2.6 -1.7 -0.9 -0.6
Mouth/teeth dental problems 0.9 1.4 4.8 0.6 1.1 1.8 1.0 1.3 1.2 0.8 0.9 1.4 1.5 1.0 2.2 0.8 1.2 1.3 1.2 0.9 1.5 1.2 1.4 1.6 0.9 0.9 1.1 0.9 0.9 1.7 0.9 1.0 1.2 1.6 1.1 1.2 1.3 0.6 1.2 1.2 1.3 1.1 0.6 1.3 0.7 1.2 0.9 1.0 1.1 1.6 0.3 0.4 0.9 1.1
Heart attack 0.2 0.2 1.3 0.7 0.2 0.7 0.4 0.2 -0.1 0.8 0.3 0.3 1.0 0.4 -0.0 0.4 0.3 0.9 0.3 0.3 -0.2 -0.1 0.1 -0.1 0.4 0.1 0.3 -0.0 0.3 -0.2 -0.4 0.1 0.0 -0.2 -0.2 -0.0 0.2 0.2 0.5 0.1 0.5 0.6 0.8 0.6 0.4 0.3 1.0 0.6 0.7 0.8 0.6 0.7 0.8 1.1
Allergy 0.1 0.2 1.9 0.4 0.2 0.3 0.1 -0.1 -0.2 -0.0 0.3 -0.1 0.4 0.5 -0.5 0.2 0.0 0.6 0.2 0.3 1.0 0.8 0.2 0.6 0.2 0.3 0.3 0.1 0.3 1.4 0.7 0.1 0.6 0.6 1.1 0.6 0.0 0.1 0.3 0.6 0.4 0.4 0.2 -0.5 -0.1 -0.1 0.2 0.5 -0.2 -0.7 -0.0 0.2 0.2 -0.2
Pain all over the body in last month 0.1 0.2 0.7 -0.6 0.3 0.4 0.3 0.3 0.1 -0.1 0.3 0.5 -0.7 -0.1 -0.9 0.3 0.3 0.3 0.2 0.3 0.3 -0.2 0.3 0.1 0.3 0.5 0.3 0.7 0.3 -0.8 0.2 0.3 0.1 -0.1 -0.2 0.1 0.5 0.7 0.0 -0.0 -0.0 -0.1 -0.3 0.1 -0.6 0.3 -0.6 -0.3 -0.3 -0.0 -0.7 -0.5 -0.4 -0.5
Diabetes (self-reported) 1.2 1.9 4.7 1.3 1.4 2.1 1.4 1.5 1.5 1.5 1.4 1.3 1.2 1.5 -0.3 1.3 1.4 0.7 1.4 1.4 0.9 1.3 1.3 1.2 1.4 1.1 1.4 1.3 1.4 -0.6 0.4 1.0 1.4 1.4 1.7 1.4 1.6 0.8 1.8 1.5 1.7 1.8 0.8 1.8 1.3 1.5 1.6 1.3 1.8 1.8 0.5 1.2 1.3 2.2
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 3.0 1.2 0.3 0.0 0.3 0.5 0.1 1.3 0.2 0.4 1.0 0.7 1.7 0.0 0.1 0.0 0.1 0.2 -0.4 0.6 0.2 0.3 0.1 -0.0 0.2 -0.2 0.2 -1.1 -0.1 0.7 0.6 -0.3 0.9 0.7 0.2 -0.3 0.9 0.2 0.8 0.8 1.2 0.8 1.3 0.2 1.2 1.3 0.9 0.6 1.2 1.3 1.2 0.7
Medication: Ramipril 0.5 0.6 2.6 0.8 0.5 0.2 0.6 0.6 0.8 1.1 0.6 0.7 0.6 1.5 1.6 0.7 0.6 1.0 0.7 0.6 0.4 0.9 0.4 0.5 0.7 0.3 0.6 0.3 0.6 0.5 0.7 0.6 0.5 0.1 0.6 0.5 0.8 0.1 0.8 0.6 0.8 0.9 1.1 1.1 0.8 0.7 1.2 1.0 1.1 1.3 0.9 0.8 1.1 1.1
Medication: Simvastatin 0.2 0.4 1.4 -0.3 0.6 0.4 0.6 0.7 0.6 -0.1 0.6 0.7 0.8 -0.0 -0.8 0.6 0.5 1.2 0.7 0.6 0.5 0.9 0.6 0.7 0.6 0.8 0.6 0.6 0.6 1.0 0.5 0.5 0.6 1.2 0.3 0.6 0.6 1.0 0.5 0.4 0.5 0.4 -0.3 0.7 0.0 0.6 -0.1 0.3 0.2 0.2 -0.5 -0.2 -0.0 -0.2
Fluid intelligence score 2.0 4.2 9.0 0.4 -2.5 -2.0 -2.4 -2.4 -2.4 -1.0 -2.5 -2.7 -0.8 -1.6 -2.4 -2.5 -2.4 -1.3 -2.5 -2.5 -2.6 -2.1 -2.4 -2.4 -2.5 -2.7 -2.5 -3.0 -2.5 -0.9 -1.8 -3.0 -2.4 -2.0 -1.9 -2.4 -2.6 -2.7 -1.8 -2.4 -2.0 -1.9 0.5 -1.7 0.3 -2.4 -0.2 -0.9 -1.0 -1.7 1.4 0.6 -0.3 -1.0
Illnesses of siblings 0.3 0.4 2.1 -1.2 -0.1 0.2 -0.2 0.0 -0.2 -1.0 -0.1 0.1 0.7 0.3 -0.4 -0.3 -0.1 -0.9 -0.3 -0.2 0.1 -0.3 0.1 -0.2 -0.2 0.2 -0.1 0.3 -0.2 -0.6 0.5 -0.0 -0.0 -0.4 -0.2 -0.1 0.1 0.2 -0.7 0.1 -0.5 -0.9 -0.7 -0.9 -1.3 -0.3 -1.2 -0.8 -1.2 -0.8 -1.0 -1.3 -1.0 -1.4
Neuroticism score 0.5 1.0 2.7 -1.0 1.3 1.1 1.1 1.5 1.2 -0.9 1.0 1.0 -0.8 0.1 -0.7 0.9 1.2 0.4 0.9 1.1 1.5 1.0 1.5 0.6 1.0 1.3 1.2 1.2 1.1 -0.3 -0.5 1.4 1.2 0.9 1.0 1.2 1.1 1.1 0.7 1.7 0.7 0.3 -0.7 -0.2 -1.3 1.4 -0.8 -0.4 -0.3 0.2 -1.1 -1.1 -0.7 -0.6
Weight 0.7 3.4 16.8 0.5 -2.2 -1.1 -2.2 -2.0 -2.3 -1.3 -2.4 -2.1 -0.4 -0.5 -1.3 -2.4 -2.2 -0.7 -2.0 -2.4 -3.3 -1.9 -2.0 -1.4 -2.4 -2.4 -2.2 -2.2 -2.4 0.7 0.3 -4.1 -2.0 -0.5 -1.9 -2.0 -2.5 -2.7 -1.3 -2.7 -1.6 -1.4 0.2 -1.8 0.4 -2.1 0.4 -0.9 -0.9 -1.9 1.2 0.8 -0.2 -0.2
Impedance of arm (right) 1.3 5.9 11.4 0.0 3.0 3.3 3.0 3.0 3.2 1.1 3.1 2.5 2.4 1.6 -0.7 3.1 3.1 2.0 2.8 3.1 3.4 2.7 2.9 2.7 3.1 2.8 3.1 2.4 3.1 1.5 1.0 3.2 2.7 1.9 2.8 2.6 3.0 2.4 2.2 3.0 2.5 2.2 0.9 2.2 -0.3 3.3 0.4 1.8 1.8 2.4 -0.2 -0.2 1.2 0.5
Arm fat percentage (right) 0.1 0.5 3.3 -0.8 0.5 1.4 0.4 0.6 0.3 -0.8 0.3 0.6 0.1 0.1 -0.6 0.2 0.4 1.1 0.4 0.3 -0.6 0.8 0.6 0.6 0.2 0.6 0.4 0.8 0.3 1.7 1.8 -0.9 0.6 0.8 -0.3 0.6 0.4 0.7 0.2 -0.1 0.2 -0.1 -0.9 -0.4 -0.8 0.1 -0.5 -0.3 -0.5 -0.8 -0.9 -0.7 -0.6 -0.6
Trunk fat-free mass 1.9 10.6 29.9 1.4 -4.1 -3.1 -4.0 -3.9 -4.1 -1.2 -4.3 -3.9 -0.9 -0.7 -0.8 -4.2 -3.9 -2.4 -3.8 -4.3 -4.7 -4.2 -3.9 -3.1 -4.3 -4.5 -4.2 -4.3 -4.3 -1.4 -1.7 -5.5 -4.0 -2.1 -2.9 -4.0 -4.2 -4.8 -2.4 -4.1 -3.0 -2.5 1.0 -2.8 1.0 -3.6 0.7 -1.4 -1.2 -2.4 2.5 1.6 -0.0 0.2
Hip circumference 1.0 4.3 17.2 1.3 -2.5 -1.5 -2.3 -2.3 -2.4 -0.8 -2.6 -2.7 0.6 -0.0 -1.9 -2.5 -2.3 -0.4 -2.1 -2.6 -3.2 -2.4 -2.3 -1.6 -2.6 -3.0 -2.5 -3.1 -2.6 1.2 -0.4 -4.2 -2.5 -0.3 -2.0 -2.5 -2.8 -3.4 -1.2 -3.0 -1.6 -1.3 1.1 -1.4 1.2 -2.3 1.1 -0.3 -0.4 -1.6 2.3 1.6 0.5 0.3
Time employed in main current job 0.3 0.4 2.6 0.2 0.6 0.5 0.6 0.6 0.4 1.0 0.5 0.3 1.6 0.6 0.1 0.5 0.5 0.6 0.7 0.6 0.8 0.7 0.5 0.5 0.5 0.7 0.5 0.5 0.6 0.9 1.0 0.5 0.7 0.8 0.7 0.8 0.7 0.8 0.7 0.6 0.5 0.8 0.2 0.4 0.2 0.8 0.1 0.5 0.5 0.3 -0.2 0.2 0.4 0.3
Alcohol intake versus 10 years previously 0.5 0.8 2.1 -0.0 -1.0 -0.9 -1.1 -1.0 -0.9 -0.5 -1.2 -0.8 0.3 -0.0 0.7 -1.1 -0.8 -0.7 -0.8 -1.2 -0.9 -1.3 -0.8 -1.0 -1.1 -1.1 -1.1 -1.1 -1.2 0.1 -1.4 -1.2 -1.3 -0.3 -1.0 -1.3 -0.7 -1.1 -0.8 -1.2 -1.0 -1.0 -0.4 -0.4 0.2 -1.1 -0.2 -0.8 -0.5 -0.9 0.2 -0.0 -0.5 -0.2
Father’s age at death 0.9 1.2 4.4 -1.8 -0.5 -0.5 -0.6 -0.4 -0.8 -2.1 -0.5 -0.4 -1.7 -1.5 -0.6 -0.5 -0.6 0.3 -0.5 -0.5 0.6 -0.2 -0.5 -0.4 -0.6 -0.1 -0.5 0.2 -0.5 0.8 -0.5 -0.3 -0.4 0.1 -0.8 -0.4 -0.7 0.3 -1.2 -0.4 -1.2 -1.4 -1.7 -1.3 -1.7 -0.6 -2.0 -1.7 -1.8 -1.4 -1.7 -1.9 -1.9 -2.0
Worrier / anxious feelings 0.2 0.5 1.8 -1.1 -0.3 -0.3 -0.4 -0.1 -0.3 -1.2 -0.4 -0.5 0.6 -0.1 -1.1 -0.4 -0.3 0.4 -0.3 -0.4 -0.0 -0.4 -0.2 -0.6 -0.5 -0.1 -0.4 -0.2 -0.4 0.2 -1.1 -0.3 -0.3 0.0 -0.5 -0.3 -0.5 0.0 -0.7 -0.2 -0.7 -0.9 -0.8 -1.0 -1.3 -0.2 -1.3 -1.0 -1.0 -0.6 -0.9 -1.2 -1.0 -1.1
Frequency of tiredness / lethargy in last 2 weeks 0.0 0.1 0.4 -0.1 0.2 0.4 0.0 0.1 -0.1 -0.4 -0.1 0.3 -0.4 -0.6 -0.4 -0.0 0.2 -0.1 -0.1 0.0 -0.7 0.1 0.2 0.2 -0.1 0.0 0.0 0.3 0.0 0.1 -0.1 -0.1 0.1 0.3 0.0 0.1 0.2 0.0 0.0 -0.0 -0.1 -0.2 -0.2 -0.6 -0.4 -0.1 -0.3 -0.3 -0.3 -0.6 -0.2 -0.0 -0.3 -0.3
Falls in the last year 0.5 0.7 2.4 -0.5 1.0 1.1 1.0 1.2 1.2 -0.2 0.9 1.0 0.8 0.9 -0.2 0.9 1.1 1.0 1.1 0.9 0.4 0.7 1.1 0.4 0.9 1.0 1.0 1.0 0.9 0.5 0.2 0.9 0.8 0.8 0.2 0.8 0.9 0.8 0.8 1.1 0.8 0.7 0.1 0.9 -0.2 1.5 -0.2 0.2 0.7 1.2 -0.3 -0.4 0.2 0.2
Hair/balding pattern: Pattern 3 0.9 1.3 7.4 -2.3 -0.2 -0.7 -0.3 -0.2 -0.5 -2.0 -0.3 -0.1 -0.3 -1.0 -0.6 -0.4 -0.2 -0.6 -0.3 -0.4 0.2 -0.6 0.0 -0.3 -0.4 0.3 -0.2 -0.2 -0.4 -0.4 -0.1 -0.1 -0.3 0.2 -1.3 -0.3 -0.3 0.7 -1.1 -0.1 -0.8 -1.2 -2.2 -2.2 -2.7 -0.2 -2.2 -2.0 -1.9 -1.3 -2.2 -2.3 -2.1 -1.4
Number of live births 7.8 11.1 15.7 1.7 3.8 2.9 3.8 3.9 3.7 3.1 3.6 3.5 2.3 3.4 3.2 3.6 3.9 3.3 3.9 3.7 2.7 3.7 3.9 4.0 3.6 3.3 3.7 2.5 3.7 2.7 3.6 3.5 3.8 3.7 3.6 3.8 4.0 2.7 3.9 3.2 3.9 3.8 1.8 3.5 1.6 3.5 2.6 3.3 3.3 3.6 0.7 1.7 2.7 3.0
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 5.4 1.3 0.2 -0.2 0.2 0.3 0.2 0.9 -0.1 -0.2 2.3 1.2 0.2 -0.1 0.3 0.2 0.3 -0.1 -0.1 0.3 0.4 0.6 -0.1 -0.2 0.1 -0.9 -0.1 1.7 0.8 -0.4 0.1 1.2 0.6 0.1 -0.3 -0.3 1.0 0.1 0.8 0.9 1.7 0.6 1.4 0.1 1.1 1.6 1.0 0.7 1.4 1.5 1.6 0.5
Pulse rate 0.1 0.2 1.3 -0.4 0.2 0.4 0.1 0.3 0.3 -0.1 0.3 0.7 0.2 0.1 0.5 0.2 -0.0 -0.6 0.1 0.4 0.8 0.6 0.2 -0.2 0.3 0.3 0.3 0.6 0.4 -1.1 0.2 0.8 0.8 -0.5 0.4 0.8 0.5 -0.1 0.1 0.7 0.3 0.3 -0.3 0.2 -0.1 0.3 0.5 -0.1 -0.0 0.9 -0.2 -0.4 -0.1 0.7
Happiness 0.4 0.5 2.3 -1.5 0.0 0.7 -0.1 0.0 -0.2 -1.3 0.0 0.0 -1.0 -0.6 -1.3 0.0 -0.0 0.4 -0.1 0.0 0.2 -0.1 -0.0 -0.0 0.0 0.3 -0.0 0.0 -0.0 0.4 -0.3 0.1 -0.1 -0.2 -0.6 -0.1 -0.0 0.2 -0.7 0.3 -0.5 -0.8 -1.4 -0.8 -1.3 0.1 -1.4 -1.3 -0.9 -0.7 -1.3 -1.4 -1.4 -0.9
Noisy workplace 0.3 0.4 5.4 0.4 -0.5 -0.3 -0.4 -0.4 -0.4 0.1 -0.4 -0.0 -0.8 -0.9 0.5 -0.4 -0.4 -0.8 -0.6 -0.5 -0.7 -0.8 -0.5 -0.6 -0.4 -0.5 -0.5 0.1 -0.5 -2.3 -1.1 -0.1 -0.6 -0.9 -0.2 -0.6 -0.7 -0.1 -0.2 -0.4 -0.3 -0.2 0.6 0.4 0.6 -0.5 0.1 0.4 0.1 0.3 0.5 0.3 0.5 -0.3
Qualifications: A levels/AS levels or equivalent 0.4 1.0 3.0 -0.0 -1.2 -1.7 -1.1 -0.8 -0.8 -0.4 -1.2 -1.6 -0.5 -0.8 -1.7 -1.3 -1.2 -0.9 -1.2 -1.2 -0.7 -1.1 -1.1 -0.9 -1.2 -1.3 -1.2 -1.5 -1.2 0.4 0.2 -1.6 -1.0 -0.6 -0.9 -1.0 -0.8 -1.4 -0.9 -0.9 -1.0 -1.0 0.2 -1.0 -0.5 -0.7 -0.1 -0.8 -0.5 -0.0 0.5 -0.1 -0.4 -0.0
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 4.8 -0.6 -0.8 -0.6 -0.8 -0.6 -0.6 -1.0 -0.7 -0.9 -0.6 -0.7 -2.2 -0.7 -0.9 0.2 -0.8 -0.7 -1.0 -1.1 -0.9 -0.8 -0.7 -0.7 -0.8 -0.9 -0.7 0.0 -0.5 -1.1 -0.8 -0.7 -0.8 -0.8 -0.6 -0.7 -1.1 -0.9 -1.0 -1.1 -0.6 -0.2 -0.4 -0.5 -0.4 -1.1 -0.5 -0.1 -0.1 -0.5 -0.7 -0.1
Mouth/teeth dental problems: Dentures 1.2 2.1 6.2 -2.1 -1.0 -1.2 -1.0 -1.4 -1.4 -2.2 -0.7 -1.0 -2.0 -1.8 -1.5 -0.7 -1.2 -0.7 -1.0 -0.7 -1.1 -0.5 -1.2 -1.1 -0.7 -0.3 -0.9 0.1 -0.7 -0.7 -0.0 -1.0 -0.8 -0.9 -1.4 -0.8 -1.3 0.1 -1.8 -1.0 -1.6 -1.6 -2.0 -1.8 -1.9 -1.1 -2.4 -1.9 -2.2 -2.4 -1.9 -2.0 -2.1 -2.5
Asthma 0.6 1.3 3.8 0.0 1.3 1.0 1.3 1.5 1.6 1.0 1.2 1.3 1.4 1.6 0.6 1.2 1.4 1.1 1.4 1.2 0.7 0.9 1.4 1.1 1.2 1.2 1.2 1.3 1.2 0.2 1.4 1.2 1.1 0.8 0.6 1.1 1.4 1.0 1.0 0.9 1.2 1.0 0.4 1.5 0.3 1.6 0.5 0.7 1.1 2.0 -0.1 -0.0 0.7 1.1
Medication: Ibuprofen (e.g. Nurofen) 1.3 1.7 5.8 1.2 -1.4 -1.6 -1.4 -1.6 -1.4 0.1 -1.4 -1.6 0.1 -0.8 0.5 -1.4 -1.4 -1.8 -1.3 -1.4 -1.7 -1.4 -1.4 -1.5 -1.4 -1.8 -1.4 -1.7 -1.4 -1.6 -1.5 -1.1 -1.2 -1.6 -1.0 -1.2 -1.6 -2.4 -0.5 -1.6 -0.7 -0.3 1.0 -0.5 1.4 -1.2 0.9 0.1 0.2 -0.7 1.6 1.3 0.7 0.4
Medication: Cholesterol lowering 0.9 1.4 5.6 -2.0 0.9 1.4 0.8 0.7 0.7 -1.3 1.1 1.1 -0.6 -1.1 -2.4 1.1 0.7 1.6 0.9 1.1 1.1 1.4 0.7 0.9 1.1 1.5 1.0 1.8 1.1 1.2 0.9 0.8 1.0 1.3 -0.3 1.0 0.8 1.7 -0.3 0.9 0.1 -0.2 -1.6 -0.2 -1.9 1.2 -1.6 -1.0 -0.8 -0.1 -2.0 -1.9 -1.4 -1.2
Depression (self-reported) 0.9 1.0 5.9 -1.5 -0.4 0.3 -0.6 -0.3 -0.9 -2.4 -0.6 -0.5 -1.2 -1.4 -1.4 -0.6 -0.3 -0.5 -0.6 -0.6 -0.6 -0.7 -0.1 -0.8 -0.6 -0.2 -0.4 0.1 -0.6 -1.7 -0.5 -1.2 -0.6 -1.1 -0.8 -0.6 -0.5 -0.0 -1.0 -0.6 -1.0 -1.2 -1.4 -0.9 -1.1 -0.4 -1.7 -1.5 -1.4 -0.9 -1.3 -1.5 -1.6 -1.7
Medication: Lansoprazole 0.1 0.1 1.1 -0.4 0.0 0.3 0.1 0.0 -0.5 0.2 0.1 0.4 1.1 0.4 0.9 0.2 0.0 0.6 -0.0 0.1 -0.2 -0.0 -0.1 -0.0 0.2 0.4 0.1 0.5 0.1 0.2 0.6 -0.4 -0.1 0.5 -0.4 -0.1 0.2 1.0 -0.2 -0.1 -0.2 -0.2 -0.6 0.1 -0.3 -0.3 -0.4 -0.1 -0.3 -0.4 -0.6 -0.4 -0.3 -0.4
Prospective memory result 2.1 2.6 6.9 1.8 1.4 1.5 1.5 1.4 1.4 1.9 1.4 1.4 0.3 1.0 2.0 1.5 1.4 1.6 1.5 1.5 1.1 1.4 1.2 1.4 1.4 1.1 1.4 1.6 1.4 1.1 1.3 1.3 1.3 0.9 2.0 1.3 1.5 1.0 1.9 1.4 1.8 2.0 1.7 2.6 2.0 1.5 1.8 2.1 2.3 2.5 1.2 1.6 2.1 2.1
Lung cancer (father) 1.2 1.4 3.5 -1.5 -1.0 -0.9 -1.1 -1.3 -1.2 -1.9 -0.9 -0.6 -1.7 -1.8 0.4 -0.9 -1.0 -0.7 -1.1 -1.0 -0.8 -1.1 -1.0 -0.9 -0.9 -0.6 -1.0 -0.2 -1.0 -0.6 -0.8 -1.1 -1.1 -1.4 -1.1 -1.1 -1.1 -0.3 -1.7 -0.7 -1.5 -1.6 -1.5 -1.2 -1.3 -0.8 -1.6 -1.6 -1.6 -1.6 -1.1 -1.4 -1.6 -1.9
Illnesses of mother 0.7 0.8 3.8 1.6 -0.4 -0.4 -0.1 -0.3 -0.0 1.0 -0.4 -0.4 1.0 1.0 1.9 -0.2 -0.2 -0.8 -0.1 -0.4 -0.9 -0.8 -0.5 -0.4 -0.2 -0.6 -0.4 -0.6 -0.4 -0.0 0.1 -1.1 -0.7 -0.5 -0.1 -0.7 -0.4 -0.5 0.4 -0.7 0.3 0.6 1.5 1.4 1.9 -0.2 1.3 1.1 1.4 1.4 1.5 1.5 1.5 1.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.7 2.3 8.4 2.3 1.0 0.8 1.0 1.2 0.9 1.7 0.7 0.6 2.9 1.9 0.7 0.6 1.1 1.1 1.1 0.7 0.7 1.0 1.2 1.5 0.6 0.4 0.9 -0.4 0.7 2.3 1.7 0.3 1.0 2.0 1.6 1.0 0.5 -0.0 2.1 0.9 1.9 2.0 2.5 1.4 2.1 0.8 2.2 2.6 2.0 1.7 2.0 2.4 2.6 1.8
Pulse wave Arterial Stiffness index 0.3 0.3 1.0 -0.6 -0.5 -0.5 -0.5 -0.6 -0.7 -0.6 -0.4 0.4 -0.6 -1.0 0.9 -0.5 -0.6 -0.1 -0.4 -0.4 -0.5 -0.1 -0.5 -0.8 -0.5 -0.2 -0.4 0.5 -0.4 -0.4 -0.2 0.0 -0.1 -0.6 -0.7 -0.1 -0.6 0.2 -0.6 -0.4 -0.5 -0.5 -1.0 -0.7 -0.4 -0.9 -0.6 -0.8 -0.8 -0.8 -0.9 -0.6 -0.8 -0.4
Impedance of arm (left) 1.6 7.3 14.4 0.3 3.4 3.4 3.4 3.2 3.6 1.4 3.4 2.6 2.4 1.7 -0.8 3.5 3.4 2.2 3.2 3.4 3.8 3.1 3.2 3.1 3.5 3.1 3.4 2.6 3.4 2.0 1.4 3.4 3.0 2.3 3.0 2.9 3.2 2.6 2.6 3.3 2.9 2.6 1.1 2.5 -0.0 3.5 0.7 2.1 2.1 2.7 -0.1 0.1 1.5 0.8
Arm fat mass (right) 0.3 1.1 6.5 -0.6 -1.0 -0.0 -1.0 -0.9 -1.1 -1.4 -1.1 -0.8 -0.4 -0.6 -1.0 -1.2 -1.1 0.1 -0.9 -1.2 -1.9 -0.6 -0.8 -0.6 -1.2 -0.9 -1.1 -0.5 -1.1 1.2 1.2 -2.5 -0.8 0.1 -1.3 -0.8 -1.1 -0.9 -0.8 -1.5 -1.0 -1.1 -0.8 -1.4 -0.6 -1.2 -0.5 -1.0 -1.1 -1.6 -0.3 -0.4 -0.9 -0.7
Trunk predicted mass 1.9 11.0 30.7 1.3 -4.2 -3.2 -4.1 -4.0 -4.2 -1.3 -4.4 -4.0 -0.9 -0.7 -0.9 -4.3 -4.0 -2.5 -3.8 -4.4 -4.8 -4.2 -4.0 -3.2 -4.3 -4.5 -4.2 -4.4 -4.3 -1.4 -1.8 -5.5 -4.1 -2.1 -3.0 -4.0 -4.3 -4.9 -2.5 -4.2 -3.1 -2.5 1.0 -2.8 1.0 -3.7 0.7 -1.5 -1.3 -2.4 2.5 1.6 -0.1 0.1
Standing height 0.6 5.8 20.8 2.3 -2.8 -1.5 -2.7 -2.6 -2.5 -0.2 -2.9 -3.2 1.0 0.5 -2.6 -2.9 -2.6 -1.4 -2.5 -3.0 -2.9 -2.9 -2.6 -1.7 -2.9 -3.6 -2.8 -3.7 -2.9 -0.4 -1.6 -4.1 -2.8 -0.9 -1.1 -2.8 -3.1 -4.6 -1.1 -2.8 -1.6 -1.0 2.7 -1.4 1.6 -1.8 1.7 0.1 0.2 -0.7 3.7 2.4 1.5 0.8
Length of working week for main job 0.8 0.9 3.1 1.0 -1.1 -1.6 -1.0 -1.4 -1.3 0.2 -0.9 -1.1 0.1 -0.6 -0.6 -0.9 -1.2 -1.0 -1.0 -0.9 -1.2 -0.7 -1.2 -1.0 -0.9 -1.3 -1.0 -1.8 -0.9 -0.2 -0.9 -0.6 -0.8 -1.3 -0.2 -0.8 -1.4 -1.5 -0.5 -1.0 -0.5 -0.3 0.7 -0.5 0.9 -1.2 0.8 0.2 0.0 -0.6 1.2 1.0 0.5 0.4
Exposure to tobacco smoke at home 1.1 1.2 3.0 0.1 1.3 1.3 1.3 1.6 1.4 0.8 1.2 1.4 1.7 1.1 -0.5 1.1 1.3 1.1 1.3 1.2 0.3 1.2 1.4 1.2 1.1 1.3 1.2 1.0 1.2 0.3 1.4 1.1 1.3 1.2 0.6 1.3 1.4 1.3 1.3 0.7 1.3 1.2 0.5 0.6 -0.0 1.3 0.4 0.9 0.8 1.0 -0.2 0.1 0.6 0.6
Breastfed as a baby 0.5 0.6 1.4 -0.4 -0.8 -1.0 -0.7 -0.9 -1.0 -0.4 -0.7 -0.6 0.6 -0.4 0.4 -0.7 -0.8 -0.2 -0.7 -0.8 -0.9 -1.1 -0.9 -0.7 -0.7 -0.8 -0.8 -0.7 -0.8 -0.3 -0.0 -1.0 -0.9 -0.6 -1.1 -1.0 -0.9 -0.8 -0.8 -0.7 -0.8 -0.8 -0.3 -1.2 -0.7 -0.9 -0.4 -0.7 -1.0 -1.1 -0.0 -0.5 -0.6 -0.9
Tense / ‘highly strung’ 1.4 2.3 5.3 1.8 1.4 1.5 1.3 1.7 1.5 1.7 1.1 1.2 1.1 2.3 0.3 1.1 1.5 1.4 1.4 1.2 1.4 1.4 1.6 1.3 1.1 0.9 1.3 0.4 1.2 1.0 0.0 1.4 1.3 1.1 2.2 1.3 1.5 0.9 2.1 1.6 1.8 1.9 1.5 2.2 1.9 1.5 1.8 1.9 2.2 2.0 1.1 1.8 1.9 2.1
Seen doctor (GP) for nerves, anxiety, tension or depression 1.9 2.9 6.4 -0.9 -1.8 -1.1 -1.9 -1.8 -2.0 -1.8 -1.8 -1.8 -1.6 -2.2 -0.6 -1.8 -1.8 -1.3 -2.0 -1.8 -1.5 -1.6 -1.8 -2.2 -1.8 -1.6 -1.9 -1.1 -1.8 -2.5 -2.2 -1.9 -1.9 -2.4 -1.5 -1.9 -1.9 -1.1 -2.1 -1.7 -2.1 -2.1 -0.9 -1.5 -0.9 -1.6 -1.5 -1.7 -1.7 -1.5 -0.4 -1.0 -1.4 -1.9
Hair/balding pattern: Pattern 4 0.2 0.4 5.4 0.4 0.3 0.1 0.4 0.2 0.1 0.1 0.3 0.1 0.6 0.4 -0.7 0.3 0.4 1.3 0.6 0.3 0.1 0.7 0.4 0.7 0.3 0.3 0.4 0.1 0.3 2.3 1.6 -0.6 0.4 1.1 0.3 0.4 0.2 0.1 0.6 0.0 0.5 0.6 0.4 0.6 0.6 0.1 0.5 0.7 0.5 0.0 0.3 0.7 0.6 0.3
Birth weight of first child 0.6 1.0 4.7 0.1 -1.0 -1.0 -1.1 -1.3 -1.3 -1.0 -1.1 -0.9 -0.6 -0.7 0.9 -1.1 -1.1 -2.2 -1.2 -1.0 -0.9 -0.9 -1.1 -1.2 -1.1 -1.1 -1.1 -1.3 -1.0 -1.6 -0.5 -1.4 -0.7 -1.7 -0.5 -0.7 -1.4 -1.0 -0.7 -0.6 -0.8 -0.7 -0.2 -1.2 -0.0 -1.3 -0.2 -0.6 -0.6 -1.3 0.1 0.3 -0.4 -0.2
Peak expiratory flow (PEF) 0.4 0.8 3.8 0.5 -1.0 -1.2 -1.1 -0.8 -0.8 -0.0 -1.2 -1.0 1.2 0.4 -0.0 -1.3 -0.9 -1.3 -1.0 -1.3 -1.3 -1.0 -0.7 -0.8 -1.3 -1.1 -1.1 -2.0 -1.3 0.1 -0.8 -1.0 -1.1 -0.1 -0.7 -1.1 -1.4 -1.2 -0.3 -0.9 -0.6 -0.4 0.7 -0.5 0.7 -0.8 0.1 0.3 -0.2 -0.8 1.0 0.7 0.5 -0.5
Pulse wave reflection index 1.3 1.6 4.6 -0.5 -1.4 -1.4 -1.4 -1.5 -1.8 -1.0 -1.4 -0.9 -1.0 -1.4 0.0 -1.5 -1.3 0.1 -1.2 -1.5 -1.5 -1.1 -1.2 -1.4 -1.5 -1.1 -1.4 -0.8 -1.5 -0.4 -0.8 -1.4 -1.3 -0.9 -1.6 -1.4 -1.7 -0.5 -1.3 -1.4 -1.3 -1.4 -1.0 -1.5 -0.4 -1.9 -1.0 -0.9 -1.5 -2.1 -0.6 -0.5 -1.0 -1.4
Ever highly irritable/argumentative for 2 days 0.9 1.0 2.7 -0.3 1.5 1.1 1.4 1.3 1.4 0.1 1.4 1.2 -0.6 0.3 -0.0 1.4 1.6 0.9 1.3 1.3 1.1 0.6 1.6 1.0 1.4 1.3 1.4 1.4 1.3 0.2 0.8 1.1 1.0 1.1 0.6 0.9 1.4 1.3 1.0 1.4 1.0 0.7 -0.7 0.0 -0.5 1.0 -0.0 0.0 0.3 -0.2 -0.9 -0.3 -0.3 0.5
Loud music exposure frequency 1.9 2.1 5.1 0.2 -1.8 -1.4 -1.7 -2.0 -2.3 -0.6 -1.6 -1.7 -0.5 -1.0 -1.7 -1.7 -1.9 -1.6 -1.7 -1.7 -1.6 -1.5 -1.8 -1.7 -1.7 -1.7 -1.6 -1.3 -1.6 -1.8 -2.2 -0.8 -1.3 -2.1 -1.3 -1.3 -2.0 -2.1 -1.2 -1.3 -1.2 -1.0 0.1 -1.4 0.2 -1.7 0.0 -0.6 -1.0 -1.5 0.7 0.3 -0.2 -0.7
Qualifications: O levels/GCSEs or equivalent 0.6 0.9 5.2 -1.8 0.5 0.2 0.5 0.5 0.1 -1.4 0.6 0.4 -0.6 -1.2 -2.3 0.5 0.3 0.1 0.2 0.5 0.3 0.4 0.5 0.6 0.5 0.8 0.5 0.8 0.6 0.4 1.2 -0.2 0.6 0.5 -0.6 0.6 0.5 0.6 -0.4 0.3 -0.2 -0.7 -1.5 -1.1 -2.1 0.3 -1.5 -1.2 -1.3 -0.9 -1.6 -1.8 -1.6 -1.4
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 6.3 0.5 0.6 0.7 0.8 0.7 0.4 0.9 0.7 0.1 1.0 0.5 -2.5 0.7 0.6 1.0 0.6 0.6 0.4 0.1 0.5 0.3 0.7 0.4 0.6 0.0 0.6 0.5 -0.2 0.5 0.3 0.5 0.4 0.2 0.6 0.5 0.8 0.6 0.7 0.6 0.6 0.2 0.1 0.3 0.7 0.7 0.5 0.1 0.4 0.6 0.7 0.7
Blood clot in the leg (DVT) 0.3 0.4 2.1 1.3 0.2 0.4 0.1 -0.1 -0.1 0.6 0.0 -0.0 0.2 -0.0 0.4 0.0 0.4 0.2 0.3 0.0 -0.3 -0.1 0.4 0.1 0.0 -0.5 0.2 -0.3 0.1 0.2 -0.1 0.1 0.1 0.3 0.4 0.1 0.0 -1.0 0.8 -0.1 0.7 0.9 1.4 0.1 1.2 -0.3 1.3 1.3 0.8 0.0 1.4 1.5 1.3 0.7
Medication: Paracetamol 0.1 0.2 3.0 -0.4 -0.3 0.1 -0.3 -0.1 -0.3 -0.7 -0.3 -0.4 -1.7 -1.1 -0.3 -0.4 -0.3 0.1 -0.3 -0.3 -0.3 -0.1 -0.2 -0.4 -0.4 -0.1 -0.3 0.1 -0.3 -0.4 -0.5 -0.1 -0.1 -0.4 0.0 -0.1 -0.3 0.2 -0.3 -0.3 -0.3 -0.4 -0.3 -0.3 -0.4 -0.2 -0.5 -0.4 -0.4 -0.1 -0.5 -0.3 -0.4 -0.3
Headache pain in last month 0.1 0.2 1.4 -0.8 -0.2 -0.6 -0.1 -0.3 -0.3 -1.2 -0.0 -0.3 0.2 -1.1 -0.1 0.0 -0.2 -0.2 -0.2 -0.1 -0.9 -0.5 -0.3 0.0 0.0 -0.2 -0.1 -0.2 -0.1 -0.2 -0.1 -0.9 -0.2 0.4 -0.9 -0.2 -0.5 -0.5 -0.6 -0.3 -0.3 -0.6 -0.6 -0.3 -0.6 -0.1 -0.5 -0.8 -0.6 -0.5 -0.3 -0.7 -0.6 -0.7
Medication for cholesterol, blood pressure or diabetes 0.8 1.2 8.2 2.2 0.0 -0.3 0.1 0.2 0.1 1.9 -0.3 -0.2 1.3 1.4 2.9 -0.3 0.2 -0.9 0.1 -0.2 -0.5 -0.6 0.2 0.1 -0.3 -0.6 -0.1 -1.0 -0.2 -0.6 -0.1 -0.3 -0.2 -0.4 1.1 -0.2 0.1 -0.8 1.1 -0.2 0.8 1.1 2.1 0.7 2.0 -0.2 1.9 1.7 1.5 0.9 2.0 2.1 2.0 1.7
Glaucoma (self-reported) 0.1 0.2 1.0 -0.4 0.3 0.4 0.4 0.0 -0.1 -0.3 0.4 0.4 -0.1 -0.1 -1.0 0.7 0.3 0.9 0.2 0.5 -0.0 -0.0 -0.0 0.2 0.6 0.4 0.3 0.3 0.4 1.0 -0.2 -0.0 -0.0 0.3 -0.1 -0.0 -0.1 0.6 -0.2 -0.0 -0.1 -0.2 -0.6 -0.3 -0.6 0.2 -0.4 -0.7 -0.0 -0.3 -0.6 -0.3 -0.6 0.3
Gout (self-reported) 1.4 1.9 8.6 1.8 0.7 0.6 0.8 1.1 1.2 2.5 0.5 0.9 2.9 2.6 1.5 0.5 0.9 0.5 0.8 0.5 0.1 0.6 0.8 0.9 0.5 0.3 0.6 -0.2 0.5 0.6 1.1 0.3 0.6 0.8 0.6 0.6 1.2 0.1 1.5 0.5 1.4 1.5 2.5 1.7 1.7 0.9 2.0 2.2 1.9 2.3 1.9 1.9 2.4 1.9
Hypothyroidism/myxoedema (self-reported) 0.1 0.3 1.8 -0.8 0.6 -0.0 0.6 0.3 0.5 -0.3 0.7 0.5 -0.2 -0.2 -0.7 0.8 0.6 0.5 0.7 0.7 0.2 0.4 0.5 0.6 0.7 0.6 0.6 0.2 0.7 0.4 0.0 0.4 0.4 1.4 -0.4 0.4 0.3 0.4 0.1 0.1 0.1 0.0 -0.6 -0.2 -0.8 0.4 -0.6 -0.3 -0.4 -0.4 -0.7 -0.8 -0.5 -0.6
Medication: Amlodipine 0.6 0.8 2.7 0.2 0.9 1.1 1.1 1.1 1.0 1.4 1.1 1.0 0.6 0.6 -0.5 1.1 1.0 1.6 1.0 1.0 0.7 1.0 0.8 0.1 1.1 1.0 1.0 1.6 1.0 -0.3 0.0 1.6 0.6 0.6 0.2 0.6 1.3 1.6 0.9 1.0 0.8 0.8 0.4 1.4 0.4 0.9 -0.2 0.9 0.7 0.7 -0.2 0.2 0.5 -0.2
Medication: Ventolin 100micrograms inhaler 1.6 2.0 5.7 1.0 1.3 1.0 1.5 1.3 1.5 2.1 1.4 1.7 2.4 2.4 1.3 1.5 1.3 1.2 1.5 1.3 0.6 1.0 1.1 1.3 1.5 1.0 1.4 0.7 1.4 0.4 1.8 1.2 1.1 1.2 1.0 1.1 1.7 0.5 1.6 1.1 1.6 1.8 1.7 1.5 0.9 1.9 1.3 1.7 1.8 1.4 1.2 1.1 1.8 1.1
Birth weight 2.6 5.6 12.0 2.3 -2.9 -2.7 -2.8 -2.6 -2.4 0.4 -3.0 -2.6 -1.1 -0.7 2.0 -3.0 -2.7 -2.3 -2.7 -3.0 -2.5 -2.9 -2.8 -2.2 -3.0 -3.5 -2.9 -3.2 -3.0 -1.6 -2.2 -2.5 -2.8 -2.2 -1.2 -2.8 -2.8 -3.4 -1.4 -2.6 -1.7 -1.1 2.6 -1.2 1.7 -2.6 1.6 0.3 0.1 0.2 3.2 2.4 1.4 1.2
Chronic bronchitis/emphysema (mother) 0.5 0.6 3.1 1.2 0.0 -0.2 -0.1 0.1 0.5 0.7 -0.1 -0.2 0.1 0.7 -0.5 -0.1 0.4 -0.6 -0.1 -0.1 -0.6 -0.5 0.3 -0.2 -0.1 -0.7 0.0 -0.7 -0.1 -1.3 -1.1 -0.4 -0.3 -0.7 0.3 -0.3 0.2 -1.3 0.3 0.1 0.3 0.3 1.2 1.1 1.4 0.1 1.6 0.7 1.1 1.1 1.8 1.3 1.1 1.2
High blood pressure (siblings) 0.1 0.2 1.1 0.1 0.3 0.2 0.3 0.3 0.5 0.6 0.3 0.1 -1.1 -0.4 -0.6 0.4 0.2 0.7 0.4 0.4 0.6 0.8 0.1 0.2 0.3 0.3 0.2 0.4 0.4 0.6 -0.2 0.5 0.3 0.6 0.2 0.3 0.1 0.7 0.3 0.1 0.3 0.4 -0.1 0.5 0.3 0.3 0.2 0.3 0.5 0.6 -0.1 0.2 0.2 0.5
Forced vital capacity (FVC), Best measure 1.1 4.0 9.0 2.3 1.7 1.8 1.8 1.8 1.6 2.2 1.6 1.4 2.9 2.1 -0.7 1.5 1.8 2.1 1.9 1.6 1.3 1.8 1.9 2.3 1.5 1.2 1.7 0.5 1.6 2.5 2.5 1.1 1.9 2.5 2.5 1.9 1.4 0.6 2.7 1.7 2.5 2.7 2.6 1.9 2.2 1.8 2.4 3.0 2.5 2.0 1.8 2.3 2.8 1.9
Body fat percentage 0.1 0.5 6.8 -0.4 0.4 1.2 0.4 0.7 0.4 -0.6 0.3 0.4 0.6 0.5 -1.1 0.3 0.4 1.5 0.4 0.2 -0.4 0.8 0.5 0.6 0.2 0.5 0.3 0.6 0.3 2.6 1.8 -1.1 0.4 1.1 -0.2 0.4 0.3 0.5 0.3 -0.2 0.2 0.0 -0.3 -0.1 -0.4 0.2 -0.2 0.0 -0.2 -0.5 -0.3 -0.3 -0.2 -0.5
Leg fat percentage (right) 0.1 0.5 5.7 -0.7 -0.3 0.4 -0.3 -0.0 -0.3 -1.0 -0.4 -0.3 -0.2 0.2 -1.2 -0.3 -0.3 1.5 -0.1 -0.5 -0.8 -0.2 -0.2 -0.1 -0.4 -0.2 -0.4 0.0 -0.4 2.4 1.1 -1.7 -0.5 0.8 -1.1 -0.5 -0.3 0.1 -0.4 -1.1 -0.6 -0.7 -0.7 -0.5 -0.6 -0.5 -0.5 -0.8 -0.6 -0.8 -0.6 -0.5 -0.8 -0.3
Arm fat-free mass (right) 1.4 7.3 22.5 0.7 -3.4 -2.6 -3.4 -3.2 -3.5 -1.4 -3.6 -3.1 -1.0 -0.8 -1.0 -3.6 -3.4 -1.7 -3.1 -3.6 -4.0 -3.2 -3.2 -2.5 -3.6 -3.6 -3.5 -3.3 -3.6 -0.5 -0.9 -4.7 -3.2 -1.4 -2.6 -3.2 -3.6 -3.8 -2.1 -3.6 -2.6 -2.2 0.4 -2.6 0.5 -3.0 0.3 -1.5 -1.4 -2.4 1.7 0.9 -0.4 -0.2
Exposure to tobacco smoke outside home 1.0 1.3 2.7 -0.7 1.4 1.4 1.3 1.3 1.0 0.5 1.4 1.6 0.9 0.7 0.8 1.3 1.2 1.0 1.2 1.4 1.2 1.2 1.3 1.5 1.3 1.6 1.4 1.5 1.4 0.6 1.2 1.6 1.6 1.5 1.2 1.6 1.5 1.4 0.8 1.2 1.0 0.6 -0.3 0.0 -0.9 1.0 -0.4 0.3 -0.2 -0.2 -1.0 -0.7 -0.2 -0.5
Comparative body size at age 10 0.5 1.3 5.8 -1.4 -0.7 -0.3 -0.7 -0.6 0.0 -1.6 -0.7 0.5 -2.4 -1.8 1.3 -0.8 -0.8 -1.5 -0.7 -0.8 -0.0 -0.5 -0.5 -0.4 -0.8 0.1 -0.7 1.3 -0.8 0.2 0.6 -0.9 -0.5 -0.5 -1.3 -0.5 -0.7 0.6 -1.1 -0.3 -1.0 -1.1 -1.6 -1.9 -1.9 -0.6 -1.9 -1.5 -1.7 -1.5 -1.8 -1.6 -1.7 -1.6
Number of full brothers 1.7 2.1 4.3 1.2 1.4 1.2 1.5 1.2 1.3 1.4 1.6 1.2 1.5 1.2 0.6 1.7 1.4 1.9 1.6 1.6 1.1 1.3 1.1 1.7 1.6 1.2 1.5 0.6 1.6 1.8 0.9 1.6 1.4 2.1 1.4 1.3 1.4 0.9 1.7 1.4 1.7 1.9 1.2 1.7 1.1 1.4 1.6 1.7 1.7 1.6 0.8 1.3 1.6 1.7
Worry too long after embarrassment 2.5 4.2 9.8 -2.0 -2.0 -1.5 -2.1 -1.8 -1.8 -3.0 -2.0 -1.6 -3.1 -2.7 -2.3 -2.0 -2.1 -1.4 -2.2 -2.0 -0.9 -1.9 -1.9 -2.1 -2.0 -1.5 -2.0 -1.2 -2.0 -1.6 -2.3 -1.4 -1.9 -1.5 -2.1 -1.9 -2.0 -1.3 -2.5 -1.6 -2.3 -2.6 -1.6 -2.7 -2.3 -1.5 -2.2 -2.6 -2.6 -1.8 -1.2 -2.1 -2.3 -2.4
Seen a psychiatrist for nerves, anxiety, tension or depression 1.5 2.0 4.8 -0.8 -1.5 -0.4 -1.5 -1.3 -1.5 -1.6 -1.6 -1.4 -1.2 -0.9 -0.4 -1.5 -1.4 -1.1 -1.6 -1.6 -0.9 -1.7 -1.4 -1.9 -1.6 -1.2 -1.5 -0.8 -1.6 -1.6 -2.2 -1.8 -1.8 -1.8 -1.5 -1.8 -1.5 -0.8 -1.7 -1.6 -1.8 -1.9 -0.7 -1.4 -1.2 -1.0 -1.3 -1.7 -1.3 -1.0 -0.4 -0.9 -1.2 -1.1
Wheeze or whistling in the chest in last year 0.2 0.3 1.4 -1.0 -0.3 0.2 -0.2 -0.3 -0.4 -0.5 -0.0 0.2 -0.2 -0.3 -0.2 -0.1 -0.4 0.0 -0.3 -0.1 -0.7 -0.5 -0.5 -0.4 -0.0 0.0 -0.2 0.4 -0.1 -0.7 0.0 -0.2 -0.2 -0.6 -1.1 -0.2 -0.1 -0.1 -0.7 -0.3 -0.6 -0.7 -0.8 -0.7 -1.2 0.3 -0.6 -1.1 -0.7 -0.6 -0.6 -0.9 -0.9 -0.6
Number of children fathered 1.1 1.3 5.9 2.2 -0.9 -1.1 -0.8 -0.8 -1.0 1.6 -1.0 -1.4 0.7 1.0 -0.1 -0.9 -0.8 -0.3 -0.6 -0.9 -0.4 -0.8 -0.8 -0.7 -0.9 -1.4 -0.9 -1.6 -0.9 -0.6 -0.4 -0.6 -0.8 -0.6 0.5 -0.8 -0.8 -1.3 0.4 -1.0 -0.0 0.5 2.4 -0.3 1.5 -1.0 1.6 1.5 0.8 0.4 2.3 2.1 1.9 1.0
Reason for reducing amount of alcohol drunk: Health precaution 1.6 1.8 6.9 2.1 -1.2 -1.0 -1.1 -1.4 -1.2 0.8 -1.2 -1.3 -0.5 0.9 0.5 -1.1 -1.0 -1.3 -1.2 -1.1 -1.3 -1.2 -1.4 -1.1 -1.1 -1.9 -1.2 -1.8 -1.1 -1.9 -2.0 -0.3 -1.3 -1.7 -0.0 -1.3 -1.4 -2.3 -0.2 -1.2 -0.4 0.1 2.1 0.6 2.3 -1.3 1.6 1.2 0.9 0.1 2.6 2.2 1.6 0.6
Age at first live birth 0.6 1.0 2.4 -0.8 -1.2 -0.5 -1.2 -1.0 -0.8 -1.1 -1.2 -1.2 -0.8 -0.7 -0.8 -1.2 -1.3 -0.7 -1.2 -1.2 -0.0 -1.1 -1.2 -1.0 -1.2 -1.0 -1.2 -0.8 -1.2 0.1 -1.2 -0.8 -1.0 -0.8 -0.7 -1.0 -1.0 -0.9 -1.3 -0.8 -1.2 -1.4 -1.0 -1.3 -0.9 -1.1 -0.6 -1.6 -1.1 -0.5 -0.5 -0.8 -1.2 -0.0
Pulse wave peak to peak time 0.2 0.3 1.6 0.8 -0.0 0.2 0.0 0.1 0.2 0.7 -0.1 -0.9 0.7 1.1 -0.9 -0.0 0.2 -0.2 -0.1 -0.1 -0.1 -0.4 -0.0 0.4 -0.1 -0.4 -0.1 -1.1 -0.1 0.1 -0.2 -0.6 -0.4 0.2 0.4 -0.4 0.1 -0.8 0.3 -0.1 0.1 0.2 1.2 0.4 0.5 0.4 0.7 0.6 0.7 0.6 1.3 0.9 0.9 0.4
Health satisfaction 0.3 0.3 2.4 -0.1 0.6 0.9 0.6 0.6 0.2 0.7 0.5 0.8 0.5 1.1 -0.2 0.5 0.7 1.1 0.7 0.5 -0.1 0.4 0.7 0.6 0.4 0.6 0.5 0.3 0.4 1.6 0.1 0.8 0.4 0.8 -0.1 0.4 0.6 0.7 0.7 0.5 0.5 0.6 -0.1 0.3 0.3 0.3 0.2 0.3 0.2 -0.1 -0.3 0.2 0.2 0.3
Shortness of breath walking on level ground 1.6 2.0 4.0 1.4 1.4 1.3 1.4 1.5 1.0 1.6 1.2 1.3 1.9 1.5 1.9 1.2 1.6 1.6 1.5 1.2 0.7 1.2 1.6 1.3 1.2 1.1 1.3 0.9 1.2 0.9 0.8 1.4 1.3 1.5 1.3 1.3 1.5 1.1 2.0 1.1 1.8 1.8 1.0 1.7 1.6 0.9 1.6 1.9 1.7 1.1 0.7 1.5 1.6 1.7
Qualifications: College or University degree 0.1 0.3 3.2 0.4 -0.3 -0.9 -0.3 -0.2 0.0 -0.2 -0.5 -1.0 0.4 -0.4 0.0 -0.4 -0.1 0.0 -0.2 -0.4 0.2 -0.4 -0.2 0.1 -0.5 -0.8 -0.4 -1.3 -0.5 1.8 -0.0 -1.1 -0.6 0.7 -0.2 -0.6 -0.3 -1.2 -0.1 -0.3 -0.2 -0.2 0.6 -0.1 0.2 -0.3 0.3 0.1 0.1 0.2 0.9 0.5 0.3 -0.1
Eye problems/disorders: None of the above 0.2 0.2 1.3 -0.3 -0.5 -0.3 -0.5 -0.5 -0.6 -0.7 -0.4 -0.1 -0.9 -1.1 0.4 -0.5 -0.6 -0.5 -0.4 -0.5 0.1 0.0 -0.4 -0.1 -0.5 -0.3 -0.4 -0.2 -0.4 0.3 -0.1 -0.2 -0.1 -0.7 0.2 -0.1 -0.3 -0.3 -0.4 -0.0 -0.4 -0.4 -0.4 -0.5 -0.1 -0.6 -0.5 -0.3 -0.7 -0.7 -0.4 -0.4 -0.5 -0.7
Mouth/teeth dental problems: Loose teeth 0.4 0.5 2.8 0.5 -0.6 -0.5 -0.6 -0.5 -0.7 -0.1 -0.8 -0.8 0.6 0.7 0.4 -0.7 -0.5 -0.5 -0.7 -0.7 -1.4 -0.6 -0.6 -0.7 -0.7 -0.9 -0.7 -1.1 -0.7 -0.4 -0.4 -1.7 -0.8 -0.9 -0.8 -0.8 -0.7 -0.7 -0.3 -1.1 -0.5 -0.5 0.7 -0.2 0.6 -1.0 0.3 0.1 -0.0 -0.3 0.8 0.7 0.4 0.1
Emphysema/chronic bronchitis 0.7 0.8 2.3 -1.0 1.0 0.8 1.0 1.2 1.0 -0.4 1.1 1.2 -0.8 -0.4 -1.3 1.1 0.9 0.5 0.8 1.1 0.9 0.6 0.8 0.4 1.2 1.3 1.0 1.5 1.1 -1.2 1.1 0.8 0.9 -0.0 0.1 0.9 1.3 1.5 0.3 0.6 0.4 0.3 -0.9 0.5 -1.0 1.3 -0.4 -0.5 0.2 0.9 -1.1 -1.0 -0.7 0.4
Medication for pain relief, constipation, heartburn 0.1 0.2 0.9 -0.8 0.2 -0.1 0.1 0.2 0.3 -0.5 0.2 0.3 0.6 0.3 -0.3 0.1 0.2 -0.3 -0.1 0.2 0.3 0.1 0.2 0.1 0.1 0.3 0.2 0.0 0.1 0.2 0.3 -0.3 0.1 -0.2 -0.1 0.1 0.2 0.1 -0.4 0.2 -0.2 -0.5 -0.9 -0.4 -0.8 -0.0 -0.6 -0.6 -0.7 -0.4 -0.7 -0.9 -0.8 -0.7
Neck or shoulder pain in last month 1.3 1.8 9.7 -0.6 -1.4 -1.1 -1.4 -1.2 -1.2 -1.2 -1.4 -1.1 -1.9 -1.7 -0.6 -1.5 -1.6 -2.1 -1.7 -1.4 -1.6 -1.3 -1.5 -1.7 -1.4 -1.1 -1.4 -1.1 -1.4 -3.1 -2.1 -1.1 -1.1 -2.1 -0.9 -1.1 -1.3 -0.7 -1.4 -0.9 -1.3 -1.2 -0.5 -1.3 -0.6 -0.9 -0.7 -1.3 -0.9 -0.5 -0.3 -0.6 -0.9 -0.3
Medication: Blood pressure 0.4 0.7 3.6 -1.5 0.4 0.6 0.3 0.2 0.2 -1.0 0.6 0.6 -0.8 -0.9 -1.9 0.6 0.1 1.5 0.4 0.6 0.7 1.2 0.2 0.3 0.6 0.9 0.5 1.2 0.6 0.9 0.0 0.8 0.7 0.6 -0.4 0.7 0.4 1.2 -0.4 0.6 -0.2 -0.3 -1.6 -0.0 -1.2 0.4 -1.1 -0.9 -0.7 -0.3 -1.7 -1.4 -1.3 -0.8
Angina (self-reported) 0.6 0.8 3.8 0.1 0.9 1.2 1.0 0.7 0.6 0.8 1.1 0.9 0.3 0.3 1.0 1.2 0.9 1.9 1.1 1.1 0.9 1.0 0.7 1.0 1.1 1.0 1.0 1.5 1.0 0.7 0.7 0.7 0.6 1.0 0.9 0.6 1.0 1.4 0.7 1.1 0.7 0.8 0.3 1.1 0.1 1.0 0.1 0.7 0.6 0.8 -0.2 0.1 0.5 0.2
Migraine (self-reported) 3.7 4.6 8.7 -2.0 2.7 2.6 2.5 2.4 2.0 -0.4 2.5 2.7 0.4 0.6 -0.5 2.5 2.8 2.6 2.6 2.5 2.3 2.2 2.9 2.7 2.5 2.9 2.7 2.9 2.5 2.0 2.6 2.5 2.4 2.7 1.3 2.4 2.6 2.8 1.2 2.2 1.5 0.9 -2.0 0.3 -1.8 2.1 -1.6 -0.4 -0.2 -0.3 -2.7 -1.9 -1.2 -1.0
Medication: Ibuprofen 0.2 0.2 1.7 0.8 -0.1 -0.2 0.0 -0.3 -0.2 0.4 0.0 -0.1 0.7 0.0 0.5 -0.1 -0.2 -1.1 -0.1 -0.0 -0.4 -0.2 -0.2 -0.2 0.0 -0.3 -0.0 -0.2 0.0 -1.3 -0.5 0.4 0.1 -0.5 -0.0 0.1 -0.2 -0.9 0.5 -0.0 0.3 0.6 0.6 0.3 1.0 0.0 0.8 0.6 0.5 -0.3 0.8 0.8 0.7 0.4
Medication: Allopurinol 0.7 0.9 6.0 1.3 -0.0 -0.0 0.0 0.5 0.6 1.5 -0.2 0.2 2.5 1.6 1.6 -0.1 0.1 -0.1 0.1 -0.2 -0.2 0.0 0.1 0.1 -0.1 -0.3 -0.1 -0.9 -0.1 0.3 0.3 -0.4 -0.1 0.2 0.0 -0.2 0.4 -0.5 0.7 -0.1 0.5 0.7 2.0 1.5 1.4 0.5 1.4 1.4 1.4 2.0 1.7 1.4 1.8 1.3
Medication: Omeprazole 0.1 0.2 2.5 0.1 -0.4 -0.8 -0.4 -0.2 -0.2 0.3 -0.5 -0.4 -0.1 -0.0 1.6 -0.5 -0.3 -0.6 -0.4 -0.4 -0.7 -0.4 -0.3 -0.2 -0.5 -0.5 -0.4 -0.2 -0.5 -0.8 -0.3 -0.3 -0.4 -0.0 -0.4 -0.4 -0.2 -0.4 -0.2 -0.2 -0.3 -0.3 0.2 -0.1 0.2 -0.3 0.1 -0.1 -0.1 0.1 0.4 0.1 0.1 -0.1
Medication: Seretide 50 evohaler 0.1 0.1 1.3 -0.2 -0.2 -0.1 -0.2 -0.3 -0.2 -0.4 -0.2 0.1 -0.9 -0.8 -0.6 -0.1 -0.3 -0.9 -0.2 -0.1 -0.5 -0.1 -0.3 -0.3 -0.1 -0.1 -0.2 -0.0 -0.1 -1.1 -0.4 -0.2 -0.1 -1.0 -0.2 -0.1 -0.1 0.1 -0.2 0.0 -0.2 -0.1 -0.1 0.4 0.3 -0.2 -0.2 -0.0 0.0 0.3 -0.1 -0.2 -0.0 -0.1
Mean time to correctly identify matches 3.3 6.2 13.6 2.7 2.3 1.9 2.5 1.9 1.8 3.2 2.4 2.0 3.0 3.5 2.4 2.5 2.4 2.2 2.6 2.5 1.9 2.6 2.0 2.8 2.5 1.6 2.4 1.2 2.5 1.9 1.8 2.4 2.3 2.5 2.8 2.2 1.8 0.9 3.2 2.2 3.0 3.4 2.8 2.9 2.9 1.8 2.8 3.7 3.0 2.0 2.0 2.7 3.3 2.1
Heart disease (mother) 0.3 0.4 1.6 -1.0 0.5 1.0 0.4 0.3 0.4 -0.6 0.6 0.7 -0.3 -0.2 -0.4 0.6 0.4 1.3 0.4 0.5 0.7 0.5 0.5 0.8 0.6 0.7 0.5 0.8 0.6 1.0 -0.0 0.9 0.6 0.7 0.5 0.5 0.5 0.6 -0.2 0.7 0.0 -0.2 -0.9 -0.1 -1.0 0.6 -0.7 -0.6 -0.5 -0.2 -1.0 -1.0 -0.8 -0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.2 0.8 0.8 0.2 0.5 0.1 -0.1 0.1 0.4 0.1 -0.1 -0.3 0.3 0.1 0.1 0.3 -0.5 0.2 0.1 -0.1 0.1 0.3 0.1 0.1 0.0 0.2 -0.2 0.1 -0.9 -0.2 0.2 0.1 0.1 0.5 0.1 -0.1 0.2 0.4 -0.1 0.5 0.6 0.5 0.3 0.9 -0.3 0.6 0.8 0.5 0.4 0.3 0.7 0.7 0.7
Whole body fat mass 0.2 0.8 6.2 -0.2 -0.8 0.2 -0.8 -0.6 -0.9 -1.0 -1.0 -0.8 0.2 0.0 -1.4 -1.0 -0.8 0.6 -0.7 -1.0 -1.6 -0.4 -0.6 -0.3 -1.1 -0.8 -0.9 -0.6 -1.0 2.0 1.3 -2.5 -0.6 0.4 -1.0 -0.6 -1.0 -0.9 -0.5 -1.4 -0.7 -0.8 -0.3 -1.1 -0.3 -0.9 -0.1 -0.5 -0.8 -1.4 0.2 -0.0 -0.4 -0.6
Leg fat mass (right) 0.4 1.7 9.0 -0.7 -1.3 -0.4 -1.4 -1.1 -1.4 -1.6 -1.5 -1.2 -0.6 -0.4 -1.6 -1.5 -1.4 0.5 -1.2 -1.6 -2.1 -1.0 -1.2 -0.8 -1.6 -1.2 -1.4 -0.9 -1.5 1.7 0.9 -3.0 -1.3 0.1 -1.7 -1.2 -1.4 -1.1 -1.1 -2.0 -1.4 -1.5 -0.9 -1.6 -0.7 -1.5 -0.6 -1.4 -1.3 -1.8 -0.3 -0.5 -1.1 -0.7
Arm predicted mass (right) 1.5 7.8 23.2 0.8 -3.5 -2.8 -3.4 -3.3 -3.6 -1.4 -3.7 -3.2 -1.2 -0.9 -0.9 -3.7 -3.5 -1.8 -3.2 -3.7 -4.1 -3.4 -3.3 -2.6 -3.7 -3.7 -3.6 -3.4 -3.7 -0.7 -1.0 -4.8 -3.3 -1.6 -2.7 -3.3 -3.7 -3.9 -2.2 -3.6 -2.7 -2.3 0.4 -2.6 0.5 -3.2 0.3 -1.5 -1.4 -2.4 1.8 1.0 -0.4 -0.2
Pulse rate, automated reading 0.2 0.6 3.8 -1.4 0.1 0.7 0.0 0.4 0.5 -0.8 0.2 0.8 -1.9 -1.4 0.2 0.1 -0.2 -0.7 0.0 0.3 1.1 0.8 0.1 -0.4 0.1 0.8 0.2 1.4 0.3 -1.1 -0.1 0.8 0.8 -0.4 0.4 0.8 0.3 1.1 -0.4 0.7 -0.1 -0.2 -1.1 -0.1 -1.1 0.2 -0.9 -0.9 -0.6 1.0 -1.6 -1.5 -1.0 0.1
Alcohol intake frequency. 0.5 1.3 5.5 -0.2 1.4 1.2 1.4 1.2 1.3 -0.1 1.3 1.0 2.3 1.3 0.6 1.3 1.4 1.4 1.5 1.3 1.1 1.2 1.4 1.4 1.3 1.3 1.3 0.7 1.3 1.2 1.1 0.2 1.2 1.8 0.6 1.2 0.8 1.0 1.3 1.0 1.3 1.2 -0.1 0.8 0.1 1.3 0.3 0.6 0.7 0.8 -0.5 -0.1 0.4 0.7
Comparative height size at age 10 0.6 3.5 11.8 0.6 -2.3 -1.3 -2.3 -2.5 -2.7 -1.3 -2.4 -2.1 -0.4 -0.9 -1.4 -2.4 -2.3 -1.4 -2.2 -2.4 -2.7 -1.8 -2.2 -1.7 -2.4 -2.4 -2.3 -2.1 -2.3 -0.5 -0.7 -3.4 -2.0 -1.5 -1.5 -2.0 -2.7 -2.7 -1.5 -2.5 -1.8 -1.3 0.7 -1.7 0.6 -2.0 -0.1 -0.6 -1.0 -1.9 1.3 0.7 -0.0 -1.0
Number of full sisters 0.6 0.7 2.7 0.3 -0.8 -1.1 -0.7 -1.1 -1.4 0.2 -0.7 -1.1 0.0 0.1 0.7 -0.7 -0.7 -1.0 -0.9 -0.8 -1.4 -1.1 -0.9 -0.6 -0.7 -0.9 -0.8 -1.1 -0.8 -1.4 -0.9 -0.7 -1.0 -0.6 -0.5 -1.0 -0.8 -0.7 -0.7 -1.2 -0.8 -0.7 -0.1 -0.7 0.1 -1.3 -0.2 -0.2 -0.7 -1.6 0.4 0.2 -0.2 -1.0
Suffer from ‘nerves’ 0.4 0.6 2.1 -0.6 0.9 1.0 0.9 1.0 1.0 -0.3 0.8 0.8 0.1 0.4 0.4 0.8 1.0 0.7 0.9 0.8 1.3 0.6 1.1 0.9 0.8 0.9 0.9 0.8 0.8 1.3 0.4 0.6 0.6 1.5 0.7 0.6 1.0 0.8 0.5 1.2 0.4 0.4 -0.5 -0.2 -1.0 1.3 -0.6 -0.5 0.1 0.1 -0.8 -0.7 -0.5 0.0
Overall health rating 0.6 1.2 3.6 -1.0 1.3 1.8 1.2 1.3 0.9 -0.8 1.3 1.3 -0.9 -0.4 -0.9 1.2 1.2 1.7 1.2 1.2 0.6 1.3 1.2 1.1 1.2 1.7 1.2 1.9 1.2 0.6 0.8 0.8 1.2 1.4 0.5 1.2 1.1 1.9 0.7 1.1 0.6 0.6 -1.2 0.5 -0.8 1.4 -0.8 -0.3 0.1 0.2 -1.6 -1.0 -0.7 0.0
Chest pain or discomfort 0.4 0.5 3.9 -1.3 0.0 0.5 0.1 -0.1 -0.4 -0.8 0.2 -0.0 -0.4 -1.4 -2.0 0.3 -0.1 1.1 0.1 0.1 0.2 -0.0 -0.2 -0.2 0.2 0.3 0.0 0.6 0.1 0.9 -0.2 0.1 -0.1 0.0 -0.7 -0.1 -0.1 0.5 -0.6 0.1 -0.6 -0.7 -1.0 -0.8 -1.3 0.1 -1.2 -1.3 -0.9 -0.7 -1.2 -1.1 -1.2 -0.6
Had major operations 0.3 0.3 2.8 -0.9 0.1 0.2 0.1 0.0 -0.2 -0.7 0.1 -0.2 -0.2 -1.2 -1.2 0.2 -0.0 1.7 0.2 0.1 0.0 0.0 -0.0 0.0 0.1 0.2 0.1 0.2 0.1 1.4 0.3 0.1 -0.0 0.6 -0.5 -0.0 0.1 0.0 -0.2 -0.2 -0.3 -0.3 -1.2 -0.4 -0.7 0.2 -0.7 -1.0 -0.5 -0.7 -1.0 -0.8 -1.0 -0.2
Age at last live birth 0.4 0.6 1.6 -0.2 -1.0 -0.2 -1.2 -0.9 -0.8 -0.2 -1.1 -0.9 -0.8 -0.4 0.1 -1.1 -1.1 -0.6 -1.0 -1.1 -0.0 -0.8 -0.9 -0.8 -1.1 -0.9 -1.0 -0.6 -1.1 -0.0 -0.9 -0.3 -0.8 -1.1 -0.2 -0.7 -0.7 -1.1 -0.8 -0.6 -0.9 -0.8 -0.3 -1.3 -0.6 -0.9 -0.0 -1.0 -0.7 -0.3 -0.1 -0.1 -0.6 0.6
Family relationship satisfaction 0.5 0.6 1.5 -1.2 0.9 1.0 0.8 0.8 0.5 -0.9 0.9 0.8 -0.8 -0.5 -1.0 0.9 0.9 0.9 0.7 0.9 0.3 0.6 0.8 0.6 0.9 0.9 0.8 0.8 0.9 0.6 0.4 0.7 0.6 0.4 -0.2 0.6 0.5 0.8 0.1 0.9 0.3 0.0 -1.2 0.1 -0.7 0.8 -0.9 -0.6 -0.2 -0.2 -1.2 -1.0 -0.9 -0.6
Leg pain on walking 3.3 4.1 6.5 -1.4 -2.2 -1.6 -2.2 -2.3 -2.2 -1.8 -2.1 -1.7 -2.0 -1.9 -1.6 -2.1 -2.3 -1.2 -2.2 -2.1 -2.2 -2.1 -2.3 -2.1 -2.1 -1.8 -2.2 -1.3 -2.1 -1.2 -2.0 -2.0 -2.2 -1.8 -2.4 -2.2 -2.2 -1.4 -2.5 -2.4 -2.5 -2.5 -1.7 -2.4 -1.4 -2.0 -1.8 -2.5 -2.2 -2.5 -0.9 -1.4 -2.1 -1.7
Qualifications: NVQ or HND or HNC or equivalent 3.6 4.4 12.3 -2.6 2.3 3.1 2.2 2.3 2.3 -1.0 2.5 2.7 -0.8 -0.8 -2.1 2.3 2.0 1.4 2.0 2.3 1.3 2.3 2.2 2.1 2.4 3.1 2.4 3.5 2.4 0.7 2.5 2.3 2.4 1.6 0.8 2.4 2.3 3.5 0.6 1.9 1.2 0.5 -2.6 1.0 -1.9 1.9 -1.6 -0.8 -0.5 0.7 -3.3 -2.6 -1.7 -0.7
Commuting to job workplace: Car/motor vehicle 0.1 0.1 1.4 0.4 -0.1 0.1 -0.0 -0.0 -0.3 1.2 -0.1 -0.2 0.9 0.4 -0.0 -0.1 0.0 -0.1 -0.0 -0.1 -0.2 -0.5 -0.0 0.0 -0.1 -0.1 -0.1 0.1 -0.1 0.3 0.1 -0.1 -0.2 -0.3 -0.1 -0.2 0.2 0.2 0.1 -0.2 0.1 0.1 0.3 0.3 0.5 -0.3 0.5 0.3 0.4 0.4 0.2 0.4 0.4 0.7
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 2.4 0.9 -0.5 -1.1 -0.5 -0.5 -0.2 0.7 -0.6 -0.8 1.5 1.1 1.1 -0.6 -0.5 -1.1 -0.4 -0.6 0.3 -0.1 -0.5 -0.5 -0.6 -0.7 -0.5 -1.4 -0.5 -0.2 -0.0 -0.3 -0.4 -0.3 0.2 -0.4 -0.8 -0.9 0.1 -0.5 -0.0 0.3 1.1 -0.1 0.7 -0.0 0.6 0.8 0.4 -0.0 1.2 0.9 1.0 -0.0
Medication: Aspirin 1.5 2.0 4.4 0.8 1.4 1.9 1.5 1.4 1.6 1.5 1.5 1.4 0.8 1.3 -0.3 1.5 1.5 2.1 1.6 1.5 1.5 1.6 1.4 1.4 1.5 1.4 1.5 1.4 1.5 1.8 0.7 2.1 1.3 1.9 1.4 1.3 1.5 1.6 1.6 1.6 1.5 1.6 0.9 1.4 0.4 1.5 1.0 1.2 1.5 1.6 0.1 0.8 1.1 1.7
Supplements: Vitamin C 1.1 1.3 3.2 0.1 -1.4 -1.8 -1.3 -1.1 -1.0 0.4 -1.3 -1.5 1.1 0.2 0.5 -1.3 -1.4 -1.2 -1.3 -1.3 -1.0 -1.4 -1.4 -1.5 -1.3 -1.4 -1.3 -1.5 -1.3 -1.4 -1.2 -1.3 -1.4 -1.1 -1.3 -1.4 -0.9 -1.6 -1.1 -1.6 -1.1 -1.0 0.4 -0.7 0.2 -1.0 0.2 -0.6 -0.5 -0.4 0.9 0.1 -0.1 -0.2
Knee pain experienced in last month 1.6 2.4 4.8 0.0 -1.9 -1.4 -1.9 -1.9 -1.8 -1.1 -1.9 -2.1 -1.2 -0.9 -0.7 -1.9 -1.8 -1.5 -1.9 -1.9 -1.9 -1.7 -1.9 -1.6 -1.9 -2.1 -1.9 -1.6 -1.9 -1.9 -1.8 -1.9 -1.9 -1.7 -1.4 -1.8 -2.1 -2.2 -1.6 -1.8 -1.7 -1.6 -0.1 -0.8 0.3 -1.6 -0.3 -1.1 -0.8 -0.9 0.8 0.1 -0.5 -0.6
Hypertension (Self-reported) 0.2 0.5 3.5 -0.3 0.5 0.7 0.5 0.7 0.1 0.6 0.6 0.8 0.6 0.4 -1.6 0.5 0.3 1.9 0.6 0.6 0.2 1.5 0.4 0.0 0.5 0.8 0.5 1.0 0.6 0.8 0.1 1.4 0.9 0.5 -0.5 0.9 0.6 1.3 0.6 0.3 0.6 0.7 -0.2 0.7 0.2 0.4 0.0 0.5 0.2 0.5 -0.6 -0.0 0.1 0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.3 1.1 0.1 -0.7 -0.7 -0.6 -0.8 -1.1 0.4 -0.5 -0.7 0.5 -0.2 0.8 -0.5 -0.8 -0.2 -0.6 -0.6 -0.4 -0.5 -0.9 -0.7 -0.5 -0.6 -0.6 -0.3 -0.6 -0.4 0.1 -0.5 -0.6 -0.7 -0.6 -0.6 -0.8 -0.5 -0.4 -0.4 -0.6 -0.4 -0.2 -0.8 -0.2 -1.0 0.0 -0.2 -0.5 -1.0 0.1 0.1 -0.2 -0.2
Illnesses of father: Heart disease 0.5 0.8 3.0 1.6 0.4 0.2 0.4 0.4 0.1 1.7 0.3 0.0 1.2 0.8 -0.2 0.3 0.5 1.3 0.5 0.4 -0.4 0.4 0.5 0.5 0.3 -0.1 0.4 -0.4 0.4 0.2 0.4 0.4 0.4 0.6 0.6 0.4 0.4 -0.0 1.0 -0.1 1.0 1.0 1.3 0.8 1.6 -0.1 1.6 1.4 1.4 1.0 1.2 1.7 1.5 1.7
Illnesses of siblings: Diabetes 0.4 0.5 3.6 1.0 0.4 0.8 0.5 0.4 0.4 0.8 0.4 0.3 0.8 0.2 0.7 0.5 0.5 1.9 0.7 0.4 0.3 0.4 0.4 0.8 0.4 0.1 0.4 0.1 0.4 1.6 0.1 0.0 0.4 0.9 0.5 0.4 0.5 -0.0 0.8 0.1 0.6 0.8 0.7 1.1 1.2 0.6 1.1 0.8 1.2 0.8 0.9 1.0 0.9 1.1
Smoking status: Previous 3.0 4.4 8.4 -0.7 -2.4 -2.3 -2.4 -2.4 -2.9 -1.1 -2.5 -2.4 -0.6 -1.2 -1.2 -2.4 -2.4 -1.5 -2.4 -2.5 -2.5 -2.6 -2.5 -2.1 -2.4 -2.5 -2.5 -2.4 -2.5 -0.7 -2.4 -2.2 -2.5 -1.8 -2.3 -2.5 -2.5 -2.1 -2.2 -2.5 -2.5 -2.4 -0.9 -2.2 -0.5 -2.7 -1.1 -1.9 -1.9 -2.5 0.1 -0.6 -1.4 -1.4
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.5 2.1 1.2 -0.5 -0.6 -0.4 -0.4 -0.1 0.1 -0.6 -0.6 1.3 0.4 -1.4 -0.6 -0.4 -0.8 -0.4 -0.6 -1.0 -0.9 -0.4 0.0 -0.6 -0.9 -0.5 -1.1 -0.6 0.3 0.2 -1.1 -0.5 0.1 0.2 -0.5 -0.7 -1.4 0.2 -0.6 0.0 0.1 1.1 -0.1 0.8 -0.4 1.2 0.4 0.5 0.3 1.4 1.2 0.9 1.1
Whole body fat-free mass 1.5 8.4 25.3 1.1 -3.6 -2.6 -3.6 -3.5 -3.8 -1.1 -3.8 -3.4 -0.8 -0.7 -1.0 -3.9 -3.5 -2.2 -3.4 -3.9 -4.4 -3.6 -3.4 -2.6 -3.9 -4.0 -3.7 -3.7 -3.8 -1.1 -1.2 -5.0 -3.4 -1.7 -2.5 -3.4 -3.8 -4.3 -2.1 -3.7 -2.7 -2.2 0.7 -2.7 0.8 -3.3 0.6 -1.3 -1.3 -2.5 2.2 1.4 -0.1 -0.1
Leg fat-free mass (right) 1.0 5.2 17.1 0.9 -2.8 -1.8 -2.8 -2.6 -3.0 -1.0 -3.0 -2.6 -0.7 -0.8 -0.9 -3.1 -2.7 -2.1 -2.7 -3.0 -3.8 -2.5 -2.5 -1.8 -3.1 -3.1 -2.9 -2.8 -3.0 -0.8 -0.5 -4.1 -2.5 -1.3 -1.9 -2.5 -3.0 -3.4 -1.6 -2.9 -2.0 -1.7 0.4 -2.4 0.6 -2.7 0.4 -0.9 -1.2 -2.5 1.7 1.0 -0.2 -0.6
Arm fat percentage (left) 0.2 0.6 4.5 -0.7 0.7 1.4 0.7 0.8 0.6 -0.7 0.6 0.7 0.0 0.2 -0.6 0.5 0.6 1.2 0.7 0.6 -0.3 1.0 0.8 0.9 0.5 0.8 0.6 1.1 0.6 2.1 2.1 -0.7 0.7 1.1 -0.1 0.8 0.6 0.9 0.4 0.1 0.4 0.1 -0.8 -0.2 -0.7 0.3 -0.4 -0.1 -0.4 -0.6 -0.9 -0.6 -0.5 -0.4
Average weekly red wine intake 0.7 1.0 4.2 1.6 -1.0 -1.6 -0.9 -1.1 -0.8 1.2 -1.0 -1.1 0.1 0.4 0.9 -1.1 -0.9 -0.8 -0.8 -1.0 -1.4 -0.8 -0.8 -0.6 -1.0 -1.3 -0.9 -1.5 -1.0 -0.4 -0.5 -1.2 -0.8 -0.8 -0.3 -0.8 -0.9 -1.3 -0.0 -0.9 -0.2 0.3 1.0 0.2 2.0 -1.3 1.2 0.8 0.6 -0.4 1.4 1.6 0.9 0.9
Handedness (chirality/laterality): Left-handed 1.6 2.0 5.4 1.3 -1.7 -2.0 -1.6 -1.9 -1.7 -0.0 -1.6 -1.9 0.1 -0.5 0.3 -1.7 -1.6 -1.4 -1.5 -1.6 -1.2 -1.3 -1.6 -1.7 -1.6 -2.0 -1.6 -2.2 -1.6 -0.8 -2.0 -1.5 -1.3 -1.6 -0.8 -1.3 -2.0 -2.3 -0.6 -1.3 -0.8 -0.4 0.9 -0.8 1.3 -1.7 1.1 0.3 -0.0 -0.8 1.6 1.5 0.7 0.7
Mood swings 0.2 0.4 1.7 -1.1 0.2 0.1 -0.0 0.3 0.0 -1.2 -0.0 -0.3 -1.3 -0.8 -1.3 -0.2 0.0 -0.3 -0.1 0.0 0.1 0.5 0.3 -0.5 -0.1 0.3 0.1 0.1 0.0 -0.7 -1.1 0.1 0.4 -0.5 0.3 0.5 -0.0 0.3 -0.1 0.6 -0.2 -0.4 -0.8 -0.8 -1.2 0.3 -1.0 -0.8 -0.9 -0.6 -1.1 -1.0 -0.9 -0.9
Loneliness, isolation 0.2 0.3 1.8 -0.9 -0.1 0.3 -0.2 -0.0 -0.3 -0.8 -0.3 -0.2 -0.8 0.0 0.1 -0.3 -0.1 -0.2 -0.3 -0.2 0.1 -0.5 -0.1 -0.7 -0.3 -0.1 -0.2 0.2 -0.3 -0.3 -1.0 -0.3 -0.3 -0.1 -0.5 -0.3 -0.2 -0.2 -0.6 -0.1 -0.6 -0.7 -0.6 -0.7 -0.7 -0.1 -1.0 -0.7 -0.8 -0.8 -0.5 -0.9 -0.7 -1.4
Long-standing illness, disability or infirmity 0.4 0.6 2.6 0.4 0.7 1.2 0.7 0.8 0.6 0.7 0.6 0.5 1.1 1.6 -0.7 0.7 0.8 1.4 0.8 0.6 0.2 0.5 0.7 0.6 0.6 0.6 0.6 0.4 0.6 0.0 -0.0 0.5 0.5 1.1 0.3 0.5 0.7 0.4 0.8 0.2 0.6 0.7 0.6 1.1 0.4 1.0 0.6 0.5 1.0 1.3 0.3 0.5 0.7 1.2
Ever had bowel cancer screening 0.4 0.5 1.2 -0.5 -0.9 -0.2 -0.8 -0.7 -0.8 -0.7 -0.9 -0.7 -0.2 -0.2 -0.5 -0.8 -1.0 -0.2 -0.8 -0.8 -0.3 -0.7 -1.0 -0.9 -0.8 -0.8 -1.0 -0.3 -0.8 -0.4 -1.1 -0.7 -0.9 -0.8 -1.0 -0.8 -0.9 -0.9 -0.8 -0.8 -1.1 -0.7 -0.1 -0.0 -0.2 0.1 -0.6 -0.8 -0.4 -0.1 0.2 -0.4 -0.4 -0.7
Diabetes diagnosed by doctor 1.9 3.2 7.3 1.8 1.7 2.4 1.8 1.8 1.9 2.4 1.7 1.7 2.0 2.2 0.6 1.7 1.7 1.1 1.8 1.7 0.9 1.5 1.6 1.4 1.7 1.4 1.7 1.5 1.7 -0.3 0.7 1.0 1.7 1.5 1.9 1.7 2.1 1.0 2.3 1.7 2.1 2.4 1.5 2.3 1.6 2.0 2.0 1.9 2.4 2.4 0.9 1.6 1.9 2.7
Ever had stillbirth, spontaneous miscarriage or termination 1.5 1.6 4.5 -1.1 -1.1 -0.9 -1.3 -0.9 -1.5 -1.3 -1.3 -0.8 -1.0 -1.6 0.3 -1.5 -1.0 -1.7 -1.4 -1.4 -1.5 -1.4 -0.7 -1.2 -1.4 -1.1 -1.1 -0.8 -1.3 -2.1 -1.2 -1.4 -1.1 -1.5 -1.1 -1.1 -1.0 -0.8 -1.4 -0.9 -1.3 -1.6 -1.2 -1.9 -1.4 -1.4 -0.9 -1.7 -1.6 -1.1 -0.7 -1.1 -1.5 -0.7
Friendships satisfaction 0.7 0.9 3.8 -1.9 0.6 1.1 0.5 0.7 0.8 -1.3 0.6 0.4 -0.5 -0.6 -2.0 0.6 0.5 1.0 0.5 0.6 0.6 0.5 0.6 0.4 0.6 0.9 0.5 1.0 0.6 1.5 0.3 0.5 0.4 0.8 -0.5 0.4 0.5 0.9 -0.5 0.8 -0.2 -0.6 -1.7 -0.5 -1.6 0.7 -1.5 -1.5 -0.8 -0.1 -1.8 -1.8 -1.6 -0.7
Qualifications: nursing, teaching 0.3 0.5 1.9 -1.0 -0.4 -0.5 -0.5 -0.3 -0.9 -0.8 -0.4 -0.4 0.1 -0.5 -0.6 -0.5 -0.5 0.9 -0.3 -0.4 -0.3 -0.2 -0.3 0.2 -0.5 -0.2 -0.4 -0.3 -0.4 1.4 0.6 -0.3 -0.2 0.8 -0.4 -0.2 -0.1 -0.3 -0.8 -0.2 -0.7 -0.9 -0.8 -1.3 -1.3 -0.4 -1.0 -1.0 -1.1 -1.0 -0.7 -1.0 -1.0 -1.2
Commuting to job workplace: Walk 2.0 2.1 7.6 1.7 -1.6 -1.6 -1.4 -1.0 -0.5 0.3 -1.7 -1.8 -0.2 0.0 0.3 -1.5 -1.2 -1.0 -1.4 -1.7 -1.8 -1.9 -1.5 -1.2 -1.6 -2.2 -1.6 -2.8 -1.7 -0.2 -1.5 -2.1 -2.0 -1.1 -0.9 -2.0 -1.1 -2.2 -0.6 -1.7 -1.0 -0.6 2.1 0.3 1.4 -0.8 1.3 0.5 0.7 0.7 2.7 1.7 1.4 0.6
Eye problems/disorders: Cataract 0.2 0.3 1.2 0.2 -0.5 -0.4 -0.5 -0.5 -0.4 0.1 -0.5 -0.7 0.5 -0.5 -0.2 -0.5 -0.4 -0.3 -0.5 -0.5 -0.9 -1.0 -0.4 -0.7 -0.5 -0.6 -0.5 -0.6 -0.6 -1.1 -0.8 -0.4 -0.7 -0.7 -1.1 -0.7 -0.3 -0.7 -0.4 -0.6 -0.4 -0.5 0.1 -0.1 -0.1 -0.3 0.3 -0.2 -0.0 0.2 0.5 0.3 0.0 0.4
Mouth/teeth dental problems: Mouth ulcers 0.6 1.0 3.6 0.7 -1.1 -1.9 -1.0 -0.9 -0.6 0.3 -1.1 -1.5 -1.2 -0.4 -0.1 -1.0 -1.0 -0.6 -1.0 -1.1 -1.0 -1.5 -1.2 -1.3 -1.0 -1.2 -1.1 -1.4 -1.1 -1.5 -1.4 -1.3 -1.2 -1.5 -0.5 -1.2 -0.9 -0.9 -0.6 -1.5 -0.9 -0.6 0.8 -0.1 0.5 -0.8 0.2 -0.1 0.2 0.3 0.9 0.7 0.4 0.4
Medication for cholesterol 0.7 1.0 5.2 -1.9 0.5 0.6 0.6 0.3 0.4 -2.1 0.8 0.6 -1.2 -1.4 -0.8 0.9 0.4 -0.1 0.3 0.7 0.2 -0.3 0.2 0.6 0.9 1.0 0.6 1.0 0.7 0.1 1.1 -0.3 0.3 0.5 -0.1 0.3 0.3 1.0 -0.8 0.6 -0.4 -0.8 -1.4 -0.8 -2.3 1.0 -1.8 -1.6 -1.0 -0.2 -1.8 -2.0 -1.6 -1.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 0.9 3.8 -1.4 0.9 1.0 0.7 1.0 0.5 -0.2 0.8 1.3 -1.4 -0.5 -0.3 0.6 0.7 -0.2 0.6 0.8 0.7 1.0 1.0 0.7 0.7 1.4 0.8 2.0 0.8 0.2 0.8 1.2 1.1 0.4 0.3 1.1 1.2 1.6 0.1 1.0 0.3 0.0 -1.1 -0.8 -1.7 0.7 -1.2 -0.7 -0.9 -0.3 -1.8 -1.6 -1.1 -0.8
Back pain experienced in last month 0.9 1.3 3.0 1.1 -1.3 -1.1 -1.1 -1.3 -1.3 0.0 -1.3 -1.2 0.1 -0.7 -0.5 -1.2 -1.2 -1.0 -1.2 -1.3 -1.3 -1.5 -1.4 -1.5 -1.2 -1.5 -1.3 -1.3 -1.2 -1.2 -1.2 -1.7 -1.4 -1.6 -0.8 -1.4 -1.6 -1.3 -0.6 -1.6 -1.0 -0.5 0.8 -0.5 0.8 -1.3 0.7 -0.2 0.0 -0.5 1.2 1.1 0.4 0.8
Mineral and other dietary supplements 1.3 1.7 6.0 1.5 1.2 0.9 1.2 1.3 1.4 0.6 1.0 0.6 1.8 1.6 1.8 1.1 1.4 1.2 1.3 1.1 1.1 1.0 1.4 1.4 1.0 0.6 1.1 -0.3 1.0 2.5 1.1 0.1 0.9 1.9 1.6 0.9 0.7 0.1 1.7 1.3 1.4 1.6 1.6 1.3 1.1 1.4 1.6 1.7 1.6 1.3 1.4 1.6 1.7 1.5
Breast cancer (self-reported) 0.4 0.5 3.0 -1.3 -0.3 0.3 -0.4 -0.3 -0.4 -1.2 -0.3 -0.2 -1.7 -0.4 -0.8 -0.3 -0.3 0.7 -0.3 -0.3 0.1 -0.2 -0.3 -0.5 -0.3 -0.0 -0.4 0.2 -0.3 0.2 -0.6 -0.3 -0.3 0.1 -0.6 -0.3 -0.3 0.1 -0.8 -0.3 -0.9 -1.0 -1.3 -0.6 -1.2 -0.1 -1.2 -1.5 -1.0 -0.9 -1.1 -1.2 -1.4 -0.8
Asthma (self-reported) 0.7 1.3 3.3 -0.4 1.4 1.0 1.3 1.6 1.7 0.8 1.2 1.4 1.3 1.5 0.4 1.3 1.4 1.1 1.4 1.3 0.9 1.0 1.4 1.1 1.3 1.4 1.3 1.5 1.3 0.2 1.4 1.4 1.1 1.0 0.5 1.1 1.5 1.4 0.9 1.0 1.0 0.8 -0.1 1.3 -0.2 1.7 0.1 0.3 0.9 1.8 -0.6 -0.5 0.2 0.9
Osteoporosis (self-reported) 1.4 1.7 3.5 -0.7 -1.6 -0.9 -1.4 -1.6 -1.5 -0.7 -1.4 -1.4 -0.6 -0.7 -1.1 -1.3 -1.7 -1.3 -1.6 -1.4 -1.7 -1.8 -1.9 -1.6 -1.3 -1.2 -1.6 -1.0 -1.4 -1.6 -1.0 -1.3 -1.7 -1.8 -1.6 -1.7 -1.4 -0.7 -1.6 -1.5 -1.8 -1.5 -0.7 -0.6 -0.3 -1.3 -0.9 -1.3 -1.1 -1.0 -0.2 -0.7 -1.0 -0.9
Osteoarthritis (self-reported) 0.7 0.9 2.9 0.1 -1.2 -1.1 -1.0 -1.3 -1.3 -0.2 -1.0 -0.9 -1.0 -0.0 0.1 -0.9 -1.1 -0.8 -1.1 -1.1 -1.3 -1.4 -1.3 -1.4 -0.9 -1.1 -1.1 -0.8 -1.1 -1.7 -1.2 -1.1 -1.4 -1.2 -1.0 -1.4 -1.2 -0.7 -1.0 -1.3 -1.1 -0.9 -0.2 -0.3 0.3 -1.0 -0.3 -0.6 -0.3 -0.6 0.3 0.2 -0.3 -0.2
Medication: Aspirin 1.0 1.3 3.1 0.6 1.1 1.4 1.2 1.1 1.3 1.2 1.2 1.1 0.3 1.0 -0.8 1.2 1.3 1.8 1.3 1.2 1.1 1.3 1.1 1.1 1.2 1.1 1.2 1.0 1.2 1.6 0.5 1.6 1.0 1.5 1.0 1.0 1.2 1.4 1.2 1.1 1.2 1.2 0.7 1.0 0.2 1.2 0.7 0.9 1.2 1.2 0.0 0.7 0.8 1.3
Medication: Gliclazide 0.7 0.8 3.3 1.6 0.3 0.2 0.5 0.5 0.8 1.5 0.3 -0.0 1.8 1.0 0.7 0.4 0.4 0.4 0.5 0.3 -0.3 -0.0 0.1 0.1 0.4 -0.1 0.3 -0.3 0.3 -0.4 -0.1 -0.4 -0.1 0.5 0.7 -0.2 0.6 0.0 1.0 0.2 0.7 1.0 1.7 1.3 1.3 0.8 1.5 1.3 1.6 1.5 1.6 1.5 1.6 1.5
Illnesses of father: None of the above (group 1) 0.4 0.5 2.2 -0.9 -0.6 -0.2 -0.5 -0.5 -0.5 -0.8 -0.4 -0.1 -1.5 -1.0 0.1 -0.5 -0.6 -0.5 -0.5 -0.5 0.5 -0.5 -0.6 -0.4 -0.5 -0.1 -0.5 0.1 -0.5 -0.2 -0.3 -0.1 -0.6 -0.5 -0.2 -0.6 -0.4 -0.1 -0.7 0.0 -0.8 -0.7 -0.5 -0.9 -1.2 -0.0 -1.3 -0.9 -1.0 -0.9 -0.8 -1.0 -0.9 -1.4
Smoking status: Current 1.8 2.9 8.0 1.0 1.8 2.5 1.9 1.6 1.4 1.9 2.0 2.6 0.8 1.0 0.8 1.8 1.6 0.9 1.7 1.9 1.4 2.4 1.7 1.6 1.9 2.0 1.9 2.4 2.0 -1.1 2.8 1.5 2.2 0.2 1.8 2.2 1.9 1.8 2.0 1.5 2.1 2.2 1.3 1.0 0.4 2.0 0.9 1.8 1.4 1.3 0.0 0.9 1.4 1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.2 4.6 10.3 2.0 2.0 1.7 2.0 2.2 2.1 2.4 1.8 1.7 2.5 1.8 1.8 1.9 2.2 2.8 2.3 1.8 1.8 1.8 2.1 2.1 1.8 1.5 1.9 1.0 1.8 2.7 1.9 1.6 1.6 2.5 2.0 1.6 1.9 1.6 2.6 1.9 2.4 2.7 2.5 2.8 2.2 2.3 1.9 2.8 3.0 3.2 1.4 2.1 2.7 2.3
Whole body water mass 1.6 9.2 27.1 1.1 -3.8 -2.8 -3.7 -3.6 -3.9 -1.3 -4.0 -3.5 -0.9 -0.8 -1.0 -4.0 -3.7 -2.3 -3.5 -4.0 -4.6 -3.7 -3.6 -2.8 -4.0 -4.1 -3.9 -3.8 -4.0 -1.2 -1.4 -5.2 -3.6 -1.9 -2.7 -3.6 -4.0 -4.4 -2.3 -3.9 -2.9 -2.4 0.6 -2.9 0.7 -3.5 0.5 -1.4 -1.4 -2.6 2.1 1.3 -0.3 -0.2
Leg predicted mass (right) 1.0 5.3 17.6 1.0 -2.8 -1.9 -2.8 -2.7 -3.0 -0.9 -3.0 -2.6 -0.7 -0.7 -0.8 -3.1 -2.7 -2.1 -2.7 -3.0 -3.8 -2.6 -2.5 -1.9 -3.1 -3.1 -2.9 -2.9 -3.0 -0.8 -0.6 -4.2 -2.5 -1.3 -1.9 -2.5 -3.0 -3.5 -1.6 -2.9 -2.0 -1.7 0.5 -2.4 0.6 -2.7 0.5 -0.8 -1.1 -2.5 1.8 1.1 -0.1 -0.5
Arm fat mass (left) 0.3 1.3 7.9 -0.5 -1.1 -0.2 -1.1 -1.0 -1.2 -1.4 -1.3 -1.0 -0.4 -0.6 -0.9 -1.3 -1.1 0.1 -1.0 -1.3 -2.0 -0.8 -1.0 -0.6 -1.3 -1.0 -1.2 -0.7 -1.3 1.4 1.0 -2.8 -1.0 0.1 -1.5 -1.0 -1.3 -1.0 -0.9 -1.7 -1.1 -1.2 -0.7 -1.5 -0.6 -1.3 -0.5 -1.1 -1.2 -1.7 -0.2 -0.4 -0.9 -0.8
Number of self-reported non-cancer illnesses 0.1 0.1 0.9 -0.5 -0.0 -0.6 -0.0 0.1 -0.2 -0.1 -0.1 0.0 0.2 -0.1 -1.0 -0.0 0.0 0.5 -0.0 -0.1 -0.4 0.1 -0.1 -0.6 -0.1 -0.0 -0.1 0.0 -0.1 -0.7 0.1 -0.3 -0.3 -0.3 -0.8 -0.2 -0.1 0.4 -0.1 -0.5 -0.3 -0.2 -0.6 0.5 0.2 -0.1 -0.3 -0.3 -0.0 0.1 -0.4 -0.3 -0.4 -0.0
Average weekly champagne plus white wine intake 0.2 0.3 2.2 0.9 -0.1 -0.4 -0.0 0.1 0.1 0.9 -0.1 -0.5 0.4 1.1 1.2 -0.1 -0.0 -0.6 -0.1 -0.1 1.5 -0.1 -0.1 -0.1 -0.1 -0.3 -0.1 -0.4 -0.1 -0.2 -0.8 0.2 -0.2 -0.1 0.7 -0.1 -0.1 -0.1 0.2 0.1 0.1 0.3 0.6 0.4 0.7 -0.1 0.6 0.7 0.6 0.6 0.8 0.6 0.7 0.4
Miserableness 0.9 1.5 5.5 -2.2 1.1 1.1 0.8 1.3 0.8 -1.8 0.9 1.0 -1.4 -0.7 -1.1 0.7 1.0 0.3 0.6 0.9 0.8 1.3 1.4 0.4 0.8 1.3 1.0 1.7 0.9 -1.0 -0.6 1.1 1.2 0.3 0.2 1.2 1.1 1.5 -0.0 1.4 0.2 -0.3 -1.7 -1.2 -2.3 0.8 -1.9 -1.1 -1.4 -0.7 -2.1 -2.3 -1.7 -2.0
Guilty feelings 1.5 2.3 5.3 -0.7 -1.5 -1.7 -1.5 -1.5 -1.8 -2.0 -1.5 -1.8 -1.3 -1.1 -0.9 -1.4 -1.4 -1.3 -1.7 -1.5 -1.2 -1.8 -1.5 -1.8 -1.5 -1.8 -1.5 -1.8 -1.5 -1.1 -2.3 -1.5 -1.8 -1.6 -1.8 -1.8 -1.9 -2.3 -1.6 -1.3 -1.7 -1.9 -0.5 -1.8 -1.1 -1.3 -0.7 -1.6 -1.4 -1.4 0.4 -0.5 -1.1 -1.1
Wears glasses or contact lenses 0.2 0.2 1.9 0.4 0.2 0.0 0.3 0.6 0.7 0.7 0.1 0.2 0.2 1.1 1.4 0.1 0.4 0.0 0.3 0.1 0.5 0.2 0.3 -0.0 0.1 0.2 0.1 0.3 0.1 0.7 0.2 0.1 0.1 0.3 0.0 0.1 0.5 0.3 0.5 0.2 0.2 0.4 0.9 0.3 0.0 0.6 0.1 0.5 0.5 0.9 0.4 0.4 0.6 0.4
Ever taken oral contraceptive pill 0.5 0.6 3.5 -0.4 -0.7 -0.6 -0.6 -0.9 -1.0 0.1 -0.6 -0.3 -0.1 -1.2 0.3 -0.6 -0.7 -1.9 -0.8 -0.6 -0.8 -0.9 -0.7 -0.7 -0.6 -0.6 -0.6 -0.4 -0.6 -1.4 -1.4 -0.0 -0.6 -0.9 -0.7 -0.6 -0.5 -0.7 -0.7 -0.2 -0.7 -0.7 -0.2 -1.2 -0.5 -0.8 -0.6 -0.4 -0.9 -1.4 0.0 -0.4 -0.4 -1.4
Hearing aid user 0.2 0.2 1.1 0.2 -0.5 -1.1 -0.4 -0.6 -0.3 -0.0 -0.4 -0.7 0.4 0.3 -0.0 -0.3 -0.4 -0.2 -0.3 -0.4 -0.5 -0.5 -0.5 -0.5 -0.3 -0.6 -0.4 -0.9 -0.4 0.1 -0.5 -0.1 -0.6 -0.1 -0.3 -0.6 -0.6 -0.6 -0.4 -0.5 -0.2 -0.2 0.7 -0.1 0.1 -0.3 0.1 0.1 0.1 0.4 0.6 0.3 0.4 0.1
Mother’s age at death 0.4 0.5 1.9 -1.1 0.6 0.6 0.6 0.5 0.4 -0.6 0.6 0.7 -0.7 -0.5 0.1 0.6 0.6 0.6 0.5 0.6 0.9 0.4 0.5 0.4 0.6 0.9 0.6 1.1 0.6 0.6 1.1 0.0 0.4 0.2 0.1 0.4 0.7 1.3 -0.1 0.6 -0.1 -0.2 -1.0 -0.5 -1.4 0.4 -1.1 -0.6 -0.7 -0.5 -1.4 -1.1 -0.9 -0.8
Financial situation satisfaction 3.0 3.7 9.7 -1.5 2.3 2.9 2.1 2.3 1.8 -0.1 2.2 2.7 -0.7 0.5 0.1 2.1 2.2 1.9 2.1 2.1 2.3 1.8 2.5 2.2 2.1 2.9 2.3 3.0 2.1 1.0 1.8 2.8 2.2 1.9 1.6 2.2 2.2 3.1 1.4 2.2 1.5 1.2 -1.6 0.3 -1.6 2.0 -1.1 -0.3 -0.0 0.6 -2.7 -1.6 -1.0 0.3
Tinnitus: Yes, now most or all of the time 0.3 0.3 1.1 1.0 -0.4 -0.3 -0.4 -0.5 -0.2 0.9 -0.5 -0.6 0.6 0.6 0.9 -0.5 -0.4 -0.8 -0.4 -0.4 -0.0 -0.4 -0.3 -0.5 -0.5 -0.6 -0.4 -0.8 -0.4 -0.9 -1.0 0.2 -0.3 -1.1 0.4 -0.3 -0.5 -0.8 0.2 -0.1 0.1 0.3 0.8 -0.3 0.7 -0.5 0.9 0.5 0.4 0.0 0.9 0.8 0.8 0.8
Commuting to job workplace: Public transport 0.1 0.1 0.9 0.0 -0.1 -0.6 -0.0 0.0 0.2 -0.8 -0.2 -0.2 -1.0 -0.5 0.2 -0.1 -0.1 -0.5 -0.2 -0.1 -0.1 0.2 -0.2 -0.2 -0.1 -0.1 -0.2 -0.1 -0.1 -0.4 0.1 -0.4 -0.2 -0.2 -0.3 -0.2 -0.4 0.1 -0.0 -0.1 -0.3 -0.2 0.3 -0.3 -0.2 0.0 -0.3 -0.1 -0.1 -0.2 0.1 0.1 0.0 -0.4
Eye problems/disorders: Glaucoma 0.2 0.3 2.5 -0.6 0.4 0.7 0.5 0.3 0.1 -0.2 0.5 0.5 0.6 0.6 -0.4 0.7 0.5 1.6 0.5 0.5 0.3 0.3 0.3 0.4 0.6 0.7 0.4 0.3 0.5 1.2 0.2 0.0 0.2 0.9 -0.1 0.2 0.1 0.8 -0.1 0.1 0.0 -0.1 -0.5 -0.3 -0.8 0.4 -0.6 -0.6 -0.0 -0.2 -0.9 -0.4 -0.5 0.3
Medication: Blood pressure 1.0 1.9 5.3 1.5 1.2 1.2 1.2 1.4 1.2 2.2 1.0 1.1 1.6 2.3 0.5 0.9 1.3 1.8 1.4 1.1 1.2 1.9 1.4 1.0 1.0 0.9 1.2 0.9 1.0 0.6 0.6 1.8 1.3 1.0 1.3 1.3 1.4 0.9 2.0 0.9 1.7 1.9 1.4 1.7 1.6 0.8 1.6 2.2 1.6 1.2 0.9 1.6 1.8 1.3
Pain type(s) experienced in last month: Hip pain 1.5 1.9 7.0 2.5 -0.8 -0.4 -0.6 -0.7 -0.5 1.9 -0.8 -0.7 0.2 1.1 0.7 -0.8 -0.7 -1.3 -0.6 -0.8 -1.6 -0.7 -0.9 -1.0 -0.8 -1.3 -0.8 -1.5 -0.7 -2.1 -0.4 -1.0 -0.7 -1.6 0.4 -0.7 -0.8 -1.6 0.7 -0.9 0.2 0.9 2.6 1.3 2.5 -0.3 2.2 1.6 1.8 1.4 2.6 2.7 2.3 2.3
Supplements: Fish oil (including cod liver oil) 0.4 0.5 1.4 -0.9 -0.8 -0.4 -0.8 -1.0 -0.9 -0.2 -0.5 -0.2 -0.7 -1.1 -0.8 -0.6 -1.1 -0.3 -0.7 -0.6 -0.6 -0.4 -1.0 -0.6 -0.5 -0.3 -0.7 0.2 -0.5 -0.8 -0.6 0.2 -0.4 -0.8 -0.9 -0.4 -0.6 0.1 -1.1 -0.8 -0.8 -0.9 -1.2 -0.7 -0.6 -0.8 -0.8 -1.1 -0.9 -0.6 -1.1 -1.0 -1.1 -0.4
High cholesterol (Self-reported) 0.3 0.6 2.1 -1.0 0.7 0.5 0.6 0.6 0.4 -0.6 0.7 0.5 0.5 -0.3 -0.5 0.7 0.6 1.3 0.7 0.7 1.0 1.4 0.7 0.7 0.7 1.0 0.7 0.9 0.7 1.4 0.7 0.5 0.8 1.2 0.1 0.8 0.3 1.2 0.2 0.5 0.2 -0.0 -1.0 -0.2 -0.9 0.3 -0.9 -0.2 -0.6 -0.7 -1.2 -0.8 -0.7 -1.0
Medication: Bendroflumethiazide 0.1 0.2 0.9 0.6 -0.1 -0.1 -0.1 -0.2 -0.3 0.7 -0.1 -0.0 0.7 0.5 -0.5 -0.1 -0.2 0.2 -0.0 -0.1 -0.4 1.0 -0.1 -0.2 -0.1 -0.2 -0.1 -0.3 -0.1 0.0 -0.4 0.0 0.2 0.0 -0.1 0.2 -0.3 -0.1 0.4 -0.2 0.3 0.4 0.2 0.1 0.8 -0.7 0.7 0.9 0.0 -0.6 0.5 0.8 0.5 -0.0
Medication: Paracetamol 0.4 0.7 2.6 -0.5 0.9 1.2 0.8 1.0 0.9 -0.5 0.8 0.8 -1.6 -0.7 -0.6 0.7 0.7 0.8 0.8 0.8 0.7 1.1 0.9 0.8 0.7 1.1 0.8 1.3 0.9 0.1 0.6 1.1 1.2 0.7 1.1 1.3 0.7 1.1 0.7 0.9 0.7 0.6 -0.4 0.4 -0.5 1.1 -0.2 0.0 0.2 0.7 -0.9 -0.4 -0.2 0.5
Medication: Lisinopril 0.2 0.2 3.4 0.6 0.0 -0.1 -0.1 0.0 0.0 1.0 0.0 0.2 0.7 0.4 -1.8 -0.1 0.0 0.5 0.1 0.0 -0.2 0.4 0.2 0.0 -0.0 -0.1 0.1 -0.1 0.0 0.2 0.0 0.6 0.3 0.4 0.1 0.3 0.5 -0.4 0.4 0.1 0.4 0.4 0.3 0.3 0.6 0.0 0.8 0.3 0.5 0.2 0.4 0.7 0.4 1.0
Medication: Atorvastatin 1.6 2.0 4.8 0.6 1.5 2.2 1.6 1.6 1.4 1.3 1.6 1.3 0.1 1.1 -1.1 1.5 1.4 1.6 1.6 1.6 1.3 1.8 1.4 1.5 1.6 1.3 1.5 1.6 1.6 0.2 1.5 1.5 1.7 1.2 1.5 1.7 1.8 1.1 1.6 1.8 1.6 1.7 0.8 1.4 0.3 1.6 0.9 1.4 1.3 1.7 0.2 0.6 1.1 1.2
Illnesses of father: High blood pressure 0.4 0.5 3.4 -1.1 -0.2 -0.4 -0.3 -0.2 -0.3 -1.9 -0.2 -0.5 -0.8 -1.4 -1.6 -0.3 -0.3 -0.3 -0.4 -0.2 -0.9 -0.3 -0.1 -0.4 -0.2 -0.2 -0.2 -0.5 -0.2 -0.3 -0.8 -0.1 -0.0 -0.6 -0.9 -0.0 -0.5 -0.5 -0.7 -0.4 -0.4 -0.8 -1.2 -0.9 -1.0 -0.4 -0.5 -1.1 -0.9 -0.6 -0.7 -0.8 -1.1 -0.3
Alcohol drinker status: Never 1.7 2.1 6.0 0.1 1.7 1.7 1.8 1.8 1.8 1.7 1.6 1.4 1.5 2.4 0.9 1.7 1.7 1.1 1.7 1.7 1.6 1.4 1.6 1.4 1.7 1.8 1.6 1.3 1.7 0.6 1.1 1.3 1.5 1.4 1.0 1.5 1.8 1.9 1.5 1.5 1.4 1.6 0.3 1.4 0.3 1.9 0.4 0.9 1.3 1.4 -0.4 0.1 0.7 1.1
Ever smoked 0.1 0.1 0.9 0.1 -0.5 -0.0 -0.3 -0.4 -0.8 0.4 -0.3 -0.2 0.6 0.0 -0.4 -0.3 -0.6 -0.0 -0.4 -0.3 -1.0 -0.1 -0.7 -0.2 -0.3 -0.4 -0.4 -0.3 -0.3 -0.5 -0.1 -0.2 -0.2 -0.5 -0.5 -0.2 -0.2 -0.4 -0.2 -0.6 -0.3 -0.1 0.3 -0.5 0.0 -0.3 0.2 -0.2 -0.2 -0.3 0.3 0.2 0.1 0.1
Basal metabolic rate 1.3 7.4 25.1 1.0 -3.4 -2.3 -3.3 -3.2 -3.5 -1.2 -3.6 -3.2 -0.7 -0.7 -1.1 -3.6 -3.3 -1.9 -3.1 -3.6 -4.3 -3.3 -3.1 -2.4 -3.6 -3.7 -3.5 -3.4 -3.6 -0.7 -0.8 -5.0 -3.2 -1.5 -2.5 -3.2 -3.6 -4.0 -2.0 -3.6 -2.5 -2.1 0.6 -2.6 0.7 -3.1 0.5 -1.2 -1.2 -2.5 2.0 1.2 -0.2 -0.1
Leg fat percentage (left) 0.1 0.5 5.3 -0.4 -0.4 0.1 -0.4 -0.1 -0.3 -0.7 -0.6 -0.5 0.0 0.2 -0.8 -0.5 -0.4 1.2 -0.3 -0.6 -1.1 -0.2 -0.3 -0.2 -0.6 -0.3 -0.5 -0.2 -0.6 2.3 1.1 -1.8 -0.5 0.7 -1.1 -0.5 -0.4 0.0 -0.3 -1.1 -0.6 -0.6 -0.4 -0.4 -0.3 -0.7 -0.4 -0.5 -0.6 -0.9 -0.3 -0.2 -0.5 -0.4
Arm fat-free mass (left) 1.8 9.4 28.3 0.8 -3.9 -2.8 -3.8 -3.6 -3.9 -1.5 -4.0 -3.5 -0.8 -1.0 -0.9 -4.0 -3.8 -2.0 -3.6 -4.1 -4.6 -3.8 -3.7 -2.9 -4.1 -4.0 -3.9 -3.8 -4.0 -0.9 -1.3 -5.3 -3.7 -1.9 -2.9 -3.6 -4.0 -4.2 -2.5 -4.1 -3.0 -2.6 0.5 -2.7 0.6 -3.5 0.3 -1.6 -1.5 -2.5 1.9 1.1 -0.4 -0.3
Number of operations (self-reported) 0.8 1.2 2.5 0.5 -1.4 -1.5 -1.2 -1.2 -1.5 0.1 -1.4 -1.3 0.4 -0.9 0.1 -1.3 -1.4 0.5 -1.1 -1.4 -1.5 -1.4 -1.4 -1.3 -1.4 -1.5 -1.4 -1.3 -1.4 -0.2 -1.2 -1.3 -1.5 -0.6 -1.2 -1.5 -1.1 -1.6 -0.6 -1.6 -1.0 -0.5 0.2 -0.3 0.7 -0.8 0.5 -0.6 -0.1 -0.4 0.8 0.5 -0.0 0.6
Average weekly beer plus cider intake 0.2 0.3 1.3 1.0 0.4 0.3 0.4 0.6 0.3 1.2 0.3 0.2 0.3 0.5 -0.0 0.3 0.4 0.1 0.4 0.3 -0.2 0.3 0.3 0.1 0.3 0.2 0.3 0.4 0.4 -0.3 -0.0 0.6 0.4 -0.3 0.5 0.4 0.4 0.2 1.0 0.4 0.5 0.8 1.0 0.7 0.6 0.3 0.9 0.9 0.7 0.6 0.6 1.0 0.9 0.9
Irritability 1.4 2.3 7.8 -0.6 -1.4 -1.9 -1.6 -1.1 -1.3 -1.2 -1.7 -1.8 -1.4 -1.3 -1.7 -1.7 -1.3 -2.6 -1.7 -1.6 -1.1 -1.7 -1.1 -2.3 -1.7 -1.4 -1.5 -1.6 -1.6 -2.8 -2.7 -1.1 -1.5 -2.1 -1.3 -1.4 -1.4 -1.1 -1.3 -1.4 -1.6 -1.6 -0.9 -1.5 -0.7 -1.5 -0.8 -1.5 -1.4 -1.4 -0.3 -0.5 -1.2 -0.7
Risk taking 1.3 1.9 7.1 1.3 1.4 0.8 1.4 1.7 1.5 1.6 1.2 1.3 1.3 2.1 2.7 1.1 1.5 0.4 1.3 1.2 0.8 0.7 1.5 1.0 1.2 0.9 1.3 0.5 1.2 -0.6 0.5 1.4 1.1 0.8 1.2 1.1 1.6 0.5 1.9 1.0 1.5 1.7 1.0 1.9 1.5 1.7 1.7 1.4 2.0 1.6 1.0 1.2 1.4 1.9
Ever had prostate specific antigen (PSA) test 0.4 0.5 1.8 -0.6 -0.5 -0.6 -0.7 -0.4 -0.4 -0.6 -0.7 -0.9 0.4 0.1 -1.3 -0.8 -0.5 0.2 -0.5 -0.7 0.4 -0.2 -0.3 -0.4 -0.8 -0.5 -0.6 -0.8 -0.7 1.1 -0.4 -0.8 -0.5 0.5 -0.4 -0.5 -0.5 -0.5 -0.7 -0.6 -0.8 -0.9 -0.5 -1.0 -0.9 -0.3 -0.8 -0.9 -0.8 -1.0 -0.3 -0.6 -0.7 -0.9
Fractured/broken bones in last 5 years 0.6 0.7 3.1 1.5 -0.5 -0.6 -0.3 -0.8 -0.9 1.3 -0.4 -0.9 0.8 0.4 -1.3 -0.2 -0.2 -0.2 -0.3 -0.4 -1.2 -0.9 -0.5 -0.6 -0.3 -1.0 -0.4 -1.2 -0.4 -0.7 -0.7 -0.5 -0.8 -0.7 -0.3 -0.8 -0.5 -1.0 0.1 -0.6 0.0 0.4 1.2 0.6 1.8 -0.7 1.3 0.9 1.0 0.2 1.7 1.6 1.3 1.0
Age started oral contraceptive pill 1.2 1.6 4.5 -1.2 1.2 1.4 1.3 1.2 1.2 -0.2 1.4 1.6 0.1 -0.1 1.0 1.5 1.1 2.1 1.4 1.4 1.9 1.9 1.0 1.3 1.4 1.7 1.3 2.1 1.4 1.5 1.0 1.4 1.2 1.7 0.7 1.2 1.2 2.0 0.5 1.2 0.7 0.4 -0.6 0.8 -1.1 1.3 -1.1 -0.0 0.1 0.9 -1.6 -1.2 -0.4 -0.6
Diastolic blood pressure, automated reading 0.3 1.1 4.5 -0.8 -1.3 -0.6 -1.3 -1.0 -1.5 -0.7 -1.2 -0.4 -0.6 -0.8 0.3 -1.2 -1.6 -0.3 -1.2 -1.2 -2.1 -0.4 -1.5 -1.5 -1.2 -0.9 -1.3 -0.7 -1.2 -0.2 -0.7 -0.4 -0.8 -1.5 -1.7 -0.8 -1.5 -0.1 -1.1 -1.2 -1.1 -1.1 -1.0 -0.1 0.2 -1.6 -0.6 -0.8 -0.8 -0.3 -0.6 -0.5 -0.9 -0.5
Ever depressed for a whole week 1.1 1.4 3.8 0.2 1.3 1.8 1.4 1.4 1.3 1.1 1.3 1.5 1.7 2.0 1.0 1.4 1.3 1.8 1.3 1.3 1.5 1.0 1.2 0.9 1.3 1.3 1.3 1.3 1.3 0.4 0.7 0.8 1.0 1.1 1.2 1.0 1.4 1.5 1.1 1.4 1.1 1.1 0.4 1.1 0.1 1.5 0.4 0.8 0.9 1.1 -0.1 0.1 0.6 0.5
Unable to work because of sickness or disability 0.2 0.2 2.8 0.5 0.3 0.4 0.3 0.6 0.5 0.7 0.1 0.1 0.5 1.7 1.5 0.1 0.5 -0.2 0.3 0.1 0.2 0.0 0.6 0.1 0.1 0.2 0.3 0.2 0.1 -0.6 -0.2 -0.2 0.1 -0.1 0.4 0.0 0.5 -0.2 0.6 0.3 0.4 0.4 0.5 0.6 0.5 0.5 0.4 0.6 0.4 0.2 0.5 0.4 0.6 0.1
Commuting to job workplace: Cycle 0.3 0.3 2.0 -0.7 -0.0 0.2 -0.1 -0.2 -0.4 -0.6 -0.1 0.2 -1.1 -0.4 0.2 -0.2 -0.0 -0.9 -0.2 -0.1 -0.2 0.1 0.1 -0.5 -0.1 0.2 -0.0 0.3 -0.1 -1.4 -0.1 -0.2 -0.1 -0.9 -0.6 -0.1 -0.2 0.5 -0.2 0.2 -0.3 -0.4 -0.5 -1.1 -1.2 -0.3 -1.1 -0.3 -1.0 -1.1 -0.9 -0.6 -0.6 -1.2
Myopia 0.7 1.0 4.1 -1.4 -0.4 0.6 -0.5 -0.3 -0.2 -1.8 -0.5 -0.2 -2.0 -2.0 -1.7 -0.6 -0.5 -1.2 -0.6 -0.5 0.6 -0.6 -0.3 -0.6 -0.5 0.2 -0.5 0.6 -0.5 -0.7 -0.7 -0.5 -0.3 -0.8 -0.3 -0.3 -0.5 0.6 -1.0 0.1 -0.9 -1.0 -1.8 -0.9 -1.5 -0.2 -1.6 -1.7 -1.3 -0.5 -1.9 -1.7 -1.8 -0.7
Vascular/heart problems diagnosed by doctor 0.1 0.3 3.0 0.2 -0.1 -0.5 -0.1 -0.1 0.4 -0.6 -0.2 -0.4 -0.4 -0.1 1.3 -0.1 0.2 -1.7 -0.3 -0.2 -0.0 -1.4 0.1 0.2 -0.1 -0.4 -0.1 -0.8 -0.2 -0.5 0.2 -1.1 -0.5 -0.2 0.4 -0.6 -0.2 -0.9 -0.3 -0.1 -0.3 -0.5 0.1 -0.4 -0.3 0.1 -0.1 -0.5 -0.1 -0.3 0.4 -0.1 -0.1 -0.2
Cholesterol lowering medication 0.6 0.8 4.2 1.9 -0.3 -0.5 -0.3 -0.2 -0.2 1.4 -0.5 -0.6 1.1 0.9 -0.1 -0.5 -0.2 0.3 -0.1 -0.4 -0.3 0.2 -0.1 -0.1 -0.5 -0.8 -0.4 -1.1 -0.4 -0.1 -0.3 -0.4 -0.1 0.0 0.8 -0.1 -0.3 -1.0 0.8 -0.5 0.5 0.8 1.3 0.6 2.0 -0.7 1.9 1.3 1.1 0.4 1.6 2.0 1.5 1.8
Medication: Omeprazole (e.g. Zanprol) 0.2 0.3 2.5 0.4 -0.5 -0.8 -0.5 -0.3 -0.2 0.4 -0.7 -0.5 0.1 0.2 1.6 -0.6 -0.4 -0.2 -0.5 -0.6 -0.9 -0.7 -0.4 -0.2 -0.7 -0.7 -0.6 -0.6 -0.7 -0.3 -0.3 -0.8 -0.6 0.3 -0.5 -0.6 -0.3 -0.6 -0.2 -0.5 -0.3 -0.3 0.4 -0.1 0.4 -0.3 0.4 -0.1 0.1 0.2 0.7 0.5 0.3 0.3
Pain experienced in last month 2.5 4.1 12.6 -1.4 2.3 2.1 2.1 2.3 2.1 0.3 2.2 2.4 0.7 1.0 1.4 2.1 2.2 2.7 2.3 2.2 2.7 2.5 2.5 2.3 2.1 2.7 2.3 2.7 2.1 3.6 3.1 2.3 2.3 2.7 1.2 2.3 2.6 2.9 1.4 2.3 1.6 1.2 -1.0 0.7 -1.2 2.0 -1.1 0.4 -0.0 0.5 -2.2 -1.4 -0.5 -0.8
Supplements: Calcium 0.7 0.8 2.3 1.1 -1.0 -0.8 -0.9 -0.8 -0.8 0.8 -1.0 -0.7 -0.5 0.5 -0.3 -1.0 -1.1 -0.6 -0.9 -0.9 -0.7 -0.6 -1.1 -0.6 -0.9 -1.1 -1.0 -0.9 -0.9 -1.2 -0.3 -0.2 -0.6 -1.1 0.2 -0.5 -0.8 -1.1 -0.2 -0.9 -0.3 0.1 1.3 0.6 1.5 -0.8 1.3 0.7 0.7 1.2 1.5 1.1 1.1 1.1
Basal cell carcinoma (self-reported) 1.3 1.5 6.9 2.4 0.2 0.0 0.4 0.3 0.3 2.5 0.3 0.4 2.1 1.6 0.9 0.3 0.3 -0.3 0.3 0.3 0.1 0.1 0.2 0.5 0.3 -0.1 0.3 -0.5 0.3 -0.7 -0.0 0.8 0.3 0.5 0.9 0.3 0.5 -0.3 1.5 0.4 1.0 1.6 2.1 1.8 2.6 0.5 2.1 2.2 1.9 0.7 2.1 2.4 2.2 1.3
Heart attack/myocardial infarction (self-reported) 0.4 0.5 1.8 0.9 0.4 0.9 0.6 0.4 0.1 1.1 0.6 0.5 1.3 0.7 0.3 0.7 0.5 1.1 0.6 0.6 -0.0 0.2 0.3 0.1 0.7 0.3 0.5 0.2 0.6 -0.2 -0.3 0.3 0.3 -0.1 0.2 0.2 0.3 0.4 0.8 0.4 0.8 0.9 1.0 0.8 0.7 0.4 1.2 1.0 1.0 1.0 0.7 0.9 1.1 1.3
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 2.3 1.3 0.0 0.3 -0.0 -0.3 -0.2 0.5 -0.1 -0.1 0.2 -0.2 0.3 -0.1 0.2 -0.0 0.1 -0.1 -0.6 -0.2 0.2 -0.1 -0.1 -0.6 0.0 -0.4 -0.1 -0.1 -0.1 -0.1 0.0 -0.0 0.3 0.0 -0.2 -1.1 0.6 -0.2 0.6 0.8 1.4 0.0 1.2 -0.4 1.3 1.2 0.7 0.1 1.5 1.5 1.3 0.6
Heart disease (siblings) 0.8 1.0 2.7 1.3 -1.0 -0.9 -0.9 -1.3 -1.4 0.2 -1.0 -1.2 -0.4 -0.9 0.1 -0.9 -0.8 0.1 -0.7 -1.0 -1.2 -1.0 -1.0 -0.9 -1.0 -1.4 -1.0 -1.7 -1.0 0.0 -1.3 -1.4 -1.1 -0.9 -0.5 -1.1 -1.2 -1.6 -0.1 -1.1 -0.4 0.1 1.1 0.2 1.5 -0.9 1.0 0.5 0.6 -0.1 1.4 1.6 0.9 0.9
Alcohol drinker status: Previous 0.4 0.5 2.0 1.4 -0.4 -0.6 -0.4 -0.7 -0.5 0.0 -0.5 -0.8 -0.3 -0.6 -0.3 -0.5 -0.4 -0.6 -0.4 -0.4 -0.5 -0.2 -0.4 0.1 -0.4 -0.9 -0.4 -1.1 -0.4 -0.4 -0.5 -1.0 -0.3 -0.2 0.8 -0.3 -0.9 -1.2 0.2 -0.4 0.2 0.3 1.0 -0.0 1.3 -0.7 1.2 0.8 0.6 -0.1 1.4 1.4 1.0 0.8
Pack years of smoking 2.8 4.1 7.1 0.9 2.3 2.3 2.4 2.2 2.5 1.3 2.5 2.3 1.1 1.4 0.9 2.4 2.3 1.6 2.3 2.4 1.5 2.4 2.2 1.8 2.4 2.0 2.4 2.1 2.4 0.5 2.3 2.1 2.4 1.8 2.3 2.4 2.5 1.5 2.3 2.7 2.4 2.4 1.2 2.0 0.8 2.4 1.6 2.0 2.0 2.0 0.6 0.9 1.6 1.5
Impedance of whole body 1.3 6.4 13.9 -0.1 3.1 3.1 3.1 3.1 3.4 1.1 3.2 2.5 2.5 1.7 -1.2 3.2 3.1 2.6 3.0 3.2 3.7 2.8 2.9 2.7 3.2 3.0 3.1 2.5 3.1 2.3 1.1 3.4 2.7 2.3 2.6 2.7 3.0 2.7 2.2 3.0 2.5 2.2 0.9 2.4 -0.3 3.4 0.3 1.7 1.8 2.7 -0.4 -0.3 1.1 0.6
Leg fat mass (left) 0.4 1.6 8.6 -0.4 -1.3 -0.4 -1.4 -1.1 -1.4 -1.3 -1.5 -1.2 -0.5 -0.3 -1.3 -1.6 -1.4 0.3 -1.2 -1.6 -2.2 -1.0 -1.2 -0.8 -1.6 -1.3 -1.4 -1.0 -1.5 1.6 0.9 -2.9 -1.2 0.1 -1.6 -1.2 -1.4 -1.2 -1.0 -2.0 -1.3 -1.3 -0.6 -1.4 -0.4 -1.5 -0.4 -1.1 -1.2 -1.7 -0.0 -0.2 -0.8 -0.7
Arm predicted mass (left) 1.9 9.6 28.6 0.9 -3.9 -2.8 -3.8 -3.7 -4.0 -1.3 -4.1 -3.6 -0.6 -0.9 -0.7 -4.1 -3.8 -2.0 -3.6 -4.1 -4.7 -3.8 -3.7 -3.0 -4.1 -4.1 -4.0 -3.9 -4.0 -1.1 -1.4 -5.3 -3.7 -1.9 -3.0 -3.7 -4.1 -4.3 -2.5 -4.1 -3.0 -2.5 0.6 -2.6 0.8 -3.5 0.4 -1.5 -1.4 -2.5 2.1 1.2 -0.3 -0.2