Best TWAS P=1.28e-07 · Best GWAS P=1.04e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | CBY1 | 0.14 | 0.03 | lasso | 2 | 0.05 | 8.4e-03 | 5.0 | 5.2 | 1.8e-07 | 0.03 | 0.02 | 0.85 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | MGAT3 | 0.14 | 0.14 | lasso | 2 | 0.12 | 3.5e-06 | 5.3 | -5.3 | 1.5e-07 | -0.99 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Nerve Tibial | SYNGR1 | 0.26 | 0.18 | enet | 27 | 0.21 | 3.6e-15 | 3.9 | 5.2 | 1.5e-07 | 0.91 | 0.08 | 0.90 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | MGAT3 | 0.13 | 0.05 | lasso | 3 | 0.02 | 4.7e-03 | 5.3 | -5.3 | 1.3e-07 | -0.99 | 0.01 | 0.98 | TRUE |