[Hub]/) : Traits : Waist Hip Ratio (WHR) :

chr2:164,657,815-166,503,040

Best TWAS P=6.72e-40 · Best GWAS P=1.6e-55 conditioned to 0.019

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex COBLL1 0.05 0.01 lasso 6 0.03 3.3e-04 13.5 -9.4 7.6e-21 0.41 0.40 0.06 TRUE
2 GTEx Breast Mammary Tissue SLC38A11 0.20 0.19 lasso 4 0.17 4.7e-09 -3.2 -5.6 2.5e-08 0.50 0.96 0.02 TRUE
3 GTEx Esophagus Muscularis GRB14 0.14 0.09 lasso 7 0.06 1.6e-04 -11.3 11.1 1.1e-28 -0.46 0.31 0.39 TRUE
4 GTEx Stomach SLC38A11 0.25 0.18 enet 13 0.26 1.0e-12 -5.3 -7.3 3.9e-13 0.18 1.00 0.00 TRUE
5 GTEx Thyroid COBLL1 0.07 0.05 lasso 3 0.05 1.5e-04 13.0 -13.2 6.7e-40 0.57 0.59 0.22 TRUE
6 METSIM Adipose GRB14 0.04 0.00 bslmm 376 0.01 1.6e-02 2.5 8.9 7.9e-19 -0.28 0.11 0.20 TRUE
7 The Cancer Genome Atlas Colon Adenocarcinoma GRB14 0.09 0.01 blup 82 0.03 4.6e-03 -14.3 9.6 6.9e-22 -0.58 0.02 0.64 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SLC38A11 0.06 0.02 blup 60 0.02 1.4e-03 -3.2 -5.5 4.6e-08 0.49 0.21 0.23 FALSE