[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr1:16,142,960-18,027,554

Best TWAS P=2.94e-11 · Best GWAS P=2.22e-10 conditioned to 0.269

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ATP13A2	0.08	0.06	lasso	5	0.08	6.9e-10	4.0	5.4	6.5e-08	-0.85	0.01	0.99	FALSE
2	GTEx	Adipose Subcutaneous	CROCC	0.18	0.15	enet	24	0.19	2.9e-15	-5.3	-5.5	4.5e-08	0.87	0.29	0.71	FALSE
3	GTEx	Adipose Subcutaneous	MST1L	0.12	0.14	lasso	4	0.11	2.0e-09	-5.8	-5.7	1.6e-08	0.84	0.03	0.97	FALSE
4	GTEx	Adipose Visceral Omentum	CROCC	0.17	0.12	lasso	5	0.17	3.6e-09	-5.3	-5.4	6.8e-08	0.93	0.06	0.94	FALSE
5	GTEx	Adipose Visceral Omentum	MST1L	0.15	0.08	enet	21	0.11	1.7e-06	3.9	-5.5	3.6e-08	0.81	0.10	0.90	FALSE
6	GTEx	Adrenal Gland	CROCC	0.16	0.00	lasso	3	0.00	2.1e-01	-5.8	-5.5	3.1e-08	0.80	0.04	0.53	FALSE
7	GTEx	Artery Aorta	CROCC	0.20	0.18	enet	23	0.20	4.0e-11	-5.8	-5.7	1.1e-08	0.84	0.01	0.99	FALSE
8	GTEx	Artery Aorta	MST1L	0.23	0.16	enet	23	0.19	7.0e-11	-5.3	-5.8	5.1e-09	0.84	0.02	0.98	FALSE
9	GTEx	Artery Tibial	MST1L	0.21	0.08	lasso	6	0.12	5.0e-10	-5.3	-5.4	5.9e-08	0.88	0.13	0.87	FALSE
10	GTEx	Brain Cerebellum	CROCC	0.30	0.25	lasso	3	0.23	2.0e-07	-5.8	-5.9	4.2e-09	0.87	0.02	0.97	FALSE
11	GTEx	Brain Cerebellum	RP11-108M9.5	0.28	0.22	lasso	4	0.20	1.7e-06	-5.8	-5.3	9.8e-08	0.85	0.02	0.89	FALSE
12	GTEx	Breast Mammary Tissue	CROCC	0.36	0.23	lasso	6	0.24	8.7e-13	-5.8	-5.5	3.0e-08	0.89	0.03	0.97	FALSE
13	GTEx	Breast Mammary Tissue	MST1L	0.23	0.14	lasso	4	0.12	8.6e-07	-5.8	-5.5	3.3e-08	0.91	0.03	0.96	FALSE
14	GTEx	Breast Mammary Tissue (Female)	MST1L	0.02	0.04	lasso	1	0.06	9.2e-03	-5.8	-5.8	7.0e-09	0.87	0.02	0.39	FALSE
15	GTEx	Cells Transformed fibroblasts	CROCC	0.27	0.11	lasso	11	0.16	7.3e-12	-5.8	-5.2	1.6e-07	0.84	0.03	0.97	FALSE
16	GTEx	Cells Transformed fibroblasts	MFAP2	0.29	0.39	enet	6	0.42	1.3e-33	-6.3	5.8	5.2e-09	-0.97	0.00	1.00	FALSE
17	GTEx	Cells Transformed fibroblasts	MST1L	0.09	0.02	enet	12	0.03	3.1e-03	-5.8	-5.7	1.6e-08	0.82	0.06	0.85	FALSE
18	GTEx	Colon Transverse	CROCC	0.20	0.14	lasso	2	0.14	2.2e-07	-5.8	-5.6	2.8e-08	0.87	0.03	0.97	FALSE
19	GTEx	Esophagus Gastroesophageal Junction	CROCC	0.21	0.10	enet	12	0.09	5.2e-04	-5.3	-5.2	2.4e-07	0.83	0.01	0.98	FALSE
20	GTEx	Esophagus Mucosa	CROCC	0.14	0.08	enet	18	0.14	9.5e-10	-5.0	-5.2	1.8e-07	0.76	0.17	0.83	FALSE
21	GTEx	Esophagus Mucosa	RP11-108M9.5	0.28	0.26	lasso	7	0.31	2.9e-21	-5.8	-5.5	2.9e-08	0.83	0.03	0.97	FALSE
22	GTEx	Esophagus Muscularis	CROCC	0.20	0.18	lasso	6	0.16	7.1e-10	-5.8	-5.9	4.7e-09	0.88	0.03	0.97	FALSE
23	GTEx	Heart Atrial Appendage	CROCC	0.13	0.10	enet	11	0.13	1.5e-06	-5.8	-6.0	2.3e-09	0.84	0.02	0.98	FALSE
24	GTEx	Heart Left Ventricle	MST1L	0.09	0.07	lasso	4	0.07	1.1e-04	-5.8	-5.8	6.3e-09	0.85	0.05	0.91	FALSE
25	GTEx	Lung	MFAP2	0.09	0.08	enet	19	0.06	1.3e-05	-4.7	5.5	3.8e-08	-0.71	0.15	0.84	FALSE
26	GTEx	Lung	RP4-798A10.7	0.11	0.05	lasso	4	0.02	1.0e-02	-5.3	-5.3	1.3e-07	0.95	0.00	0.99	FALSE
27	GTEx	Muscle Skeletal	MST1L	0.17	0.12	lasso	9	0.15	3.5e-14	-5.8	-5.9	3.3e-09	0.93	0.04	0.96	FALSE
28	GTEx	Nerve Tibial	CROCC	0.19	0.15	enet	8	0.19	2.4e-13	-5.8	-5.8	8.7e-09	0.94	0.03	0.97	FALSE
29	GTEx	Nerve Tibial	MFAP2	0.09	0.06	lasso	3	0.07	9.7e-06	3.9	5.2	1.7e-07	-0.75	0.09	0.90	FALSE
30	GTEx	Nerve Tibial	ATP13A2	0.05	0.03	lasso	5	0.03	4.8e-03	-5.1	5.4	5.7e-08	-0.67	0.23	0.64	FALSE
31	GTEx	Nerve Tibial	MST1L	0.23	0.16	lasso	7	0.22	6.6e-16	-5.8	-6.0	1.8e-09	0.86	0.03	0.97	FALSE
32	GTEx	Ovary	RP11-108M9.5	0.32	0.14	lasso	6	0.09	2.9e-03	-5.8	-6.7	2.9e-11	0.87	0.02	0.86	TRUE
33	GTEx	Skin Not Sun Exposed Suprapubic	CROCC	0.16	0.12	lasso	7	0.15	9.9e-09	-3.8	-5.2	1.6e-07	0.90	0.02	0.98	FALSE
34	GTEx	Skin Not Sun Exposed Suprapubic	MST1L	0.15	0.15	lasso	4	0.13	8.2e-08	-5.8	-5.7	1.4e-08	0.84	0.05	0.95	FALSE
35	GTEx	Skin Sun Exposed Lower leg	CROCC	0.19	0.13	enet	30	0.21	3.4e-17	-5.8	-5.6	2.6e-08	0.79	0.02	0.98	FALSE
36	GTEx	Skin Sun Exposed Lower leg	NBPF1	0.14	0.04	lasso	7	0.05	2.9e-05	-5.3	-5.8	7.1e-09	0.85	0.26	0.74	FALSE
37	GTEx	Small Intestine Terminal Ileum	CROCC	0.32	0.07	lasso	14	0.18	7.9e-05	-5.8	-6.4	1.2e-10	0.85	0.06	0.33	FALSE
38	GTEx	Testis	NBPF1	0.12	-0.01	enet	11	0.00	6.1e-01	-5.5	-5.4	5.7e-08	0.62	0.06	0.22	FALSE
39	GTEx	Thyroid	CROCC	0.28	0.12	lasso	8	0.25	3.5e-19	-4.7	-5.7	1.3e-08	0.72	0.64	0.36	FALSE
40	GTEx	Thyroid	MST1L	0.08	0.03	lasso	11	0.03	1.8e-03	-4.7	-6.1	1.1e-09	0.71	0.08	0.69	FALSE
41	GTEx	Whole Blood	CROCC	0.07	0.09	lasso	2	0.06	2.1e-06	-5.8	-5.8	8.1e-09	0.87	0.02	0.98	FALSE
42	GTEx	Whole Blood	MST1P2	0.05	0.02	enet	14	0.04	1.8e-04	-6.3	5.6	1.9e-08	-0.68	0.01	0.98	FALSE
43	METSIM	Adipose	CROCC	0.16	0.12	lasso	3	0.14	1.7e-20	-3.8	-5.2	2.5e-07	0.90	0.13	0.87	FALSE
44	NTR	Blood	CROCC	0.03	0.03	lasso	5	0.03	8.8e-09	-5.8	-5.8	7.1e-09	0.86	0.02	0.98	FALSE
45	YFS	Blood	CROCC	0.02	0.02	lasso	5	0.01	2.1e-05	-5.8	-5.5	4.5e-08	0.91	0.05	0.95	FALSE
46	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CROCC	0.09	0.04	lasso	4	0.06	1.3e-05	-5.8	-5.5	3.8e-08	0.86	0.01	0.98	FALSE
47	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CROCC	0.02	0.01	enet	12	0.02	5.6e-03	-5.4	-5.1	2.8e-07	0.86	0.01	0.90	FALSE
48	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MFAP2	0.17	0.22	enet	10	0.23	6.8e-26	-4.6	5.3	1.3e-07	-0.76	0.94	0.06	FALSE
49	The Cancer Genome Atlas	Brain Lower Grade Glioma	ATP13A2	0.05	0.05	lasso	3	0.07	2.6e-08	-5.3	5.8	6.6e-09	-0.95	0.03	0.97	FALSE
50	The Cancer Genome Atlas	Brain Lower Grade Glioma	CROCC	0.08	0.03	enet	6	0.06	5.2e-07	-5.8	-5.7	1.0e-08	0.71	0.03	0.95	FALSE
51	The Cancer Genome Atlas	Brain Lower Grade Glioma	MFAP2	0.02	0.02	lasso	1	0.02	2.4e-03	-5.3	5.3	9.4e-08	-0.98	0.00	0.94	FALSE
52	The Cancer Genome Atlas	Rectum Adenocarcinoma	ATP13A2	0.13	0.06	lasso	3	0.08	6.4e-03	-5.4	5.5	3.9e-08	-0.87	0.02	0.40	FALSE
53	The Cancer Genome Atlas	Stomach Adenocarcinoma	CROCC	0.06	0.06	lasso	1	0.05	2.8e-04	-5.4	-5.3	8.8e-08	0.85	0.02	0.73	FALSE