Hub : Genes

NUDT6

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0440	0.0200	6.3e-03	0.042	0.004	0.021	0.014	0.023	7.1e-06	1.0e-01	1.1e-03	0.00670	6.5e-04
2	GTEx	Artery Tibial	0.0799	0.0384	8.2e-03	0.075	NA	0.051	NA	0.053	1.7e-06	NA	6.9e-05	NA	5.6e-05
3	GTEx	Brain Cerebellar Hemisphere	0.3200	0.0930	3.0e-04	0.072	NA	0.165	NA	0.112	6.5e-03	NA	5.0e-05	NA	8.6e-04
4	GTEx	Breast Mammary Tissue	0.2500	0.0830	2.2e-04	0.105	NA	0.052	NA	0.084	5.0e-06	NA	1.2e-03	NA	4.2e-05
5	GTEx	Breast Mammary Tissue (Male)	0.2898	0.1284	9.7e-03	-0.004	NA	-0.012	NA	-0.001	4.1e-01	NA	7.8e-01	NA	3.5e-01
6	GTEx	Breast Mammary Tissue (Female)	0.3009	0.1082	7.5e-03	-0.010	NA	0.003	NA	-0.009	9.0e-01	NA	2.5e-01	NA	7.8e-01
7	GTEx	Muscle Skeletal	0.1468	0.0391	4.2e-08	0.118	NA	0.099	NA	0.107	1.4e-11	NA	6.2e-10	NA	1.1e-10
8	GTEx	Nerve Tibial	0.1128	0.0417	9.9e-04	0.075	NA	0.037	NA	0.049	5.3e-06	NA	1.2e-03	NA	2.1e-04
9	GTEx	Skin Not Sun Exposed Suprapubic	0.0720	0.0330	5.6e-03	0.024	NA	0.017	NA	0.026	1.7e-02	NA	3.8e-02	NA	1.5e-02
10	GTEx	Skin Sun Exposed Lower leg	0.1110	0.0380	1.3e-04	0.078	NA	0.063	NA	0.077	5.3e-07	NA	6.0e-06	NA	6.2e-07
11	GTEx	Thyroid	0.0650	0.0290	8.9e-04	0.032	NA	0.052	NA	0.053	1.7e-03	NA	7.5e-05	NA	6.9e-05
12	ROSMAP	Brain Pre-frontal Cortex	0.0412	0.0185	6.6e-03	0.035	0.023	0.027	0.024	0.026	2.1e-05	5.7e-04	2.0e-04	0.00044	2.6e-04
13	TCGA	Breast Invasive Carcinoma	0.0217	0.0112	2.3e-03	0.018	0.006	0.003	NA	0.009	1.2e-04	2.1e-02	7.5e-02	NA	5.4e-03
14	TCGA	Brain Lower Grade Glioma	0.0506	0.0207	2.0e-05	0.058	0.044	0.041	NA	0.050	3.3e-07	8.2e-06	1.7e-05	NA	2.0e-06
15	TCGA	Lung Adenocarcinoma	0.0414	0.0212	4.3e-03	0.006	0.007	0.007	NA	0.002	6.0e-02	4.5e-02	4.5e-02	NA	1.9e-01
16	TCGA	Pheochromocytoma and Paraganglioma	0.1300	0.0730	4.2e-03	0.006	0.034	-0.005	NA	0.007	1.8e-01	1.6e-02	5.7e-01	NA	1.7e-01
17	TCGA	Prostate Adenocarcinoma	0.1008	0.0351	1.3e-07	0.071	0.061	0.066	NA	0.069	6.9e-08	5.5e-07	1.7e-07	NA	1.0e-07

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	1.0	1.6	3.0	1.4	1.4	-1.1	1.2	0.3	1.1	1.4	1.5	1.3	0.6	0.9	1.7	1.5	1.3	0.8	1.5	1.5
Bipolar Disorder or Schizophrenia	0.4	0.9	4.2	0.8	0.8	-1.3	1.4	0.3	2.0	0.8	1.0	1.4	0.6	0.1	0.8	0.8	0.6	0.1	0.8	0.6
Depressed Affect (Nagel 2018)	0.6	1.2	2.3	1.3	1.5	-0.8	0.3	0.5	-0.4	1.3	1.4	1.0	1.3	1.2	1.5	1.2	0.8	0.7	1.1	0.9
Depression (Nagel 2018)	0.1	0.1	0.7	0.0	0.1	0.7	0.3	-0.9	-0.5	0.0	0.2	0.5	-0.2	0.2	0.6	0.1	-0.1	0.1	-0.2	-0.1
Intelligence (Savage-Jansen 2018)	0.1	0.3	2.4	-0.3	-0.1	-0.5	-0.4	-0.7	-1.5	-0.3	-0.6	-0.2	-0.4	0.6	-0.1	-0.2	-0.6	-0.6	-0.2	-0.0
Neuroticism (Nagel 2018)	0.1	0.2	0.5	0.4	0.6	0.3	0.4	-0.3	0.2	0.5	0.4	0.7	0.2	0.2	0.6	0.4	0.1	-0.6	0.5	0.1
Schizophrenia (2018)	0.2	0.4	3.0	-0.1	-0.2	-0.8	0.9	0.2	1.7	-0.1	0.1	0.8	0.3	-0.6	-0.4	-0.2	-0.3	-0.5	-0.4	-0.5
Schizophrenia vs Biploar Disorder	0.1	0.1	0.5	0.1	0.2	-0.7	-0.1	-0.2	0.4	0.1	0.2	0.1	0.5	0.3	0.1	0.1	-0.2	-0.3	-0.3	0.2
Worry (Nagel 2018)	0.2	0.3	1.3	-0.2	-0.1	0.4	1.1	-0.7	0.9	-0.2	-0.2	0.6	-0.4	-0.6	-0.1	-0.2	-0.5	-1.1	-0.4	-0.4
Alzheimer’s Disease (in mother)	0.8	1.0	3.7	0.3	0.7	-1.4	1.9	1.3	1.5	0.5	1.1	1.0	1.2	-0.7	0.5	0.6	0.2	-0.5	-0.6	0.9
Alzheimer’s Disease (in father)	1.5	1.6	4.5	1.1	1.2	-0.9	1.9	2.1	1.2	1.1	1.7	1.6	1.4	-0.2	1.0	1.2	1.1	0.7	0.3	1.3
Alzheimer’s Disease (including proxy)	1.7	2.5	7.5	1.1	1.4	-1.6	2.7	2.2	1.7	1.2	2.1	1.9	1.8	-1.0	1.2	1.3	0.9	-0.1	-0.1	1.7
Crohns Disease (2017)	1.3	2.8	4.6	1.8	1.8	0.1	2.1	1.7	-0.0	1.8	2.0	2.1	1.6	-0.3	2.0	1.9	1.9	1.2	1.2	2.1
Irritable Bowel Disease (IBD)	0.3	0.6	2.6	0.2	0.2	0.3	1.1	1.6	0.5	0.3	1.0	0.4	1.3	-1.2	0.7	0.4	0.8	0.3	-0.3	0.8
Ulcerative Colitis (UC)	0.5	0.9	2.0	-1.3	-1.2	-0.0	-0.2	0.6	0.8	-1.2	-0.4	-1.3	0.2	-1.4	-0.7	-1.2	-0.7	-0.9	-1.4	-0.7
Major Depression (MDD)	0.6	0.8	1.6	1.0	0.9	-0.0	0.5	0.7	-0.1	1.0	1.1	0.6	1.2	0.6	1.2	1.0	1.0	0.9	0.6	1.2
Reaction Time	0.4	0.8	3.2	0.9	0.5	1.3	0.3	0.1	-1.4	0.8	0.5	0.9	0.4	-1.0	0.3	0.6	1.1	1.8	0.3	0.7
Verbal and Numeric Reasoning (VNR)	0.2	0.4	3.0	0.6	0.6	-1.7	0.2	-0.5	0.2	0.6	0.5	0.3	0.3	0.8	0.6	0.4	-0.1	-0.0	-0.2	0.6
Breast Cancer	0.5	1.2	3.2	-0.9	-0.9	-0.8	-1.4	-1.4	-1.8	-1.3	-0.9	-1.5	-1.1	0.2	-0.7	-1.1	-1.4	-0.5	-0.8	-0.8
Ovarian Cancer	0.3	0.4	3.1	0.2	0.1	0.1	0.5	1.8	-0.9	0.2	0.7	0.5	1.2	0.3	0.0	0.1	0.1	-0.0	-0.3	0.1
Prostate Cancer	0.2	0.3	1.4	-0.0	-0.2	-0.3	-0.8	-1.1	-1.2	-0.2	-0.3	-0.7	-0.2	-0.5	-0.1	-0.2	-0.1	0.6	-0.3	-0.0
Age at First Birth	1.7	2.5	6.1	1.6	1.9	-0.7	1.8	1.0	0.4	1.6	1.5	2.5	1.4	1.6	2.0	1.8	1.2	1.2	2.2	1.4
Bipolar Disorder (2011)	0.7	0.7	3.6	0.4	0.3	-1.5	-0.2	0.0	-1.2	0.3	0.4	0.3	0.2	1.9	0.5	0.5	0.3	1.3	1.3	0.6
Body Mass Index (BMI) (2010)	0.3	0.4	2.5	-0.1	0.2	0.1	0.5	0.5	0.7	-0.0	0.3	-0.5	0.6	-1.3	0.2	0.0	-0.4	-1.6	-0.7	-0.1
Coronary Artery Disease (CAD)	0.3	0.4	1.0	-0.3	-0.2	-0.8	-1.0	-0.6	0.7	-0.4	-0.5	-0.9	-0.7	0.1	-0.4	-0.3	-0.7	-0.6	-0.5	-0.5
Crohns Disease (2012)	3.0	4.8	7.3	2.6	2.5	-0.0	2.4	2.1	1.1	2.5	2.6	2.5	2.1	0.1	2.4	2.5	2.6	2.0	2.1	2.7
Mean Putamen Volume	3.6	4.1	6.8	-2.4	-2.4	1.8	-1.3	-2.0	-1.3	-2.4	-2.6	-2.0	-2.5	-1.2	-1.9	-2.2	-1.9	-1.2	-2.4	-2.1
Fasting Glucose	0.3	0.4	1.4	-0.7	-0.5	-0.3	-1.1	0.7	-0.9	-0.6	0.3	-0.7	1.2	-0.2	0.2	-0.2	0.1	-0.5	0.1	-0.1
HbA1C	0.4	0.5	3.6	-0.3	-0.3	1.9	-1.0	-0.5	-0.6	-0.3	-0.4	-0.7	-0.5	0.2	-0.5	-0.1	0.3	0.2	0.9	-0.2
HDL Cholesterol	1.0	1.7	4.5	1.4	1.4	-1.2	0.5	1.3	1.0	1.3	1.4	0.7	0.9	0.3	1.4	1.6	2.1	2.1	0.6	1.5
LDL Cholesterol	0.7	1.1	3.1	1.2	1.2	0.7	0.7	-0.1	0.8	1.2	1.5	0.9	1.0	-0.3	1.7	1.3	0.9	0.6	1.5	1.0
Lupus	4.8	7.2	13.3	-3.1	-3.0	0.7	-1.1	-2.1	-0.3	-3.2	-3.0	-2.4	-2.4	-2.0	-3.3	-3.2	-3.1	-3.1	-3.7	-3.1
Neuroticism (2016)	0.1	0.1	0.6	0.4	0.4	0.1	-0.2	0.0	-0.4	0.3	-0.0	-0.2	-0.0	0.8	0.7	0.3	0.3	0.3	0.1	0.2
Primary Biliary Cirrhosis	2.4	3.4	6.3	-2.3	-2.3	0.8	-1.2	-1.1	-0.1	-2.2	-2.3	-1.8	-2.1	-1.2	-2.5	-2.2	-1.8	-1.1	-2.2	-2.3
Rheumatoid Arthritis	0.5	0.6	3.0	-0.3	-0.4	1.6	-1.7	-0.2	-1.4	-0.1	-0.3	-1.5	-0.0	-0.6	-0.2	-0.4	0.2	0.4	-0.0	-0.2
Schizophrenia (2014)	0.4	0.9	4.4	0.1	0.0	0.4	1.9	0.2	1.9	0.2	0.3	1.4	0.3	-2.1	-0.1	0.1	0.1	-0.8	-0.5	-0.1
Triglycerides	1.8	3.0	4.5	-2.1	-1.9	1.3	-2.1	-1.7	-1.7	-2.1	-1.9	-2.1	-1.7	0.6	-1.8	-2.0	-1.9	-1.1	-0.8	-1.9
Type 2 Diabetes (T2D) (2012)	0.9	1.0	4.5	-1.3	-1.0	2.1	-1.8	-0.3	-1.0	-1.1	-0.5	-0.4	-0.2	0.7	-0.2	-0.7	0.0	0.9	1.1	-0.8
Ulcerative Colitis	0.3	0.4	1.3	-0.9	-0.8	0.1	0.1	0.9	0.6	-0.8	0.1	-0.6	0.5	-1.1	-0.4	-0.7	-0.1	-0.0	-1.1	-0.3
Blood Eosinophil Count	0.8	6.0	22.4	2.1	1.4	4.7	1.9	0.9	0.4	2.0	1.6	1.9	1.5	-4.4	2.2	1.8	3.3	3.4	0.8	2.3
Blood Platelet Count	0.2	1.9	4.0	-1.3	-1.6	2.0	0.7	-1.1	-1.5	-1.3	-1.3	1.3	-1.5	1.1	-1.3	-1.4	-1.4	-1.2	0.5	-1.9
Blood Red Count	0.2	2.2	3.9	1.6	1.7	-0.7	1.3	1.2	-0.3	1.7	2.0	1.6	1.6	1.1	1.4	1.7	1.6	0.9	2.0	1.8
Blood White Count	0.0	0.3	1.7	0.1	-0.5	1.1	-0.6	-0.2	-1.3	0.1	-0.5	-0.1	0.1	0.1	-0.2	-0.4	0.0	0.5	0.5	-0.3
Heel T-Score	0.5	3.7	8.8	-1.5	-1.7	1.1	-2.6	-2.8	-2.9	-1.9	-1.9	-1.0	-2.3	3.0	-1.2	-1.7	-1.5	0.8	0.9	-1.8
BMI	0.4	2.5	5.4	1.9	1.8	-1.1	1.4	1.5	1.8	2.2	1.8	0.8	1.7	0.2	2.3	1.9	1.2	-0.9	1.0	1.6
Height	2.6	49.2	78.9	8.2	8.3	-7.8	8.9	8.5	6.9	8.0	7.5	8.3	7.9	1.3	6.2	7.7	5.4	1.4	1.7	7.5
Waist Hip Ratio (WHR)	3.8	16.9	61.3	-4.1	-4.5	1.2	-3.3	-4.2	-7.8	-4.4	-4.5	-1.6	-4.6	4.9	-3.8	-4.3	-4.4	-1.0	-0.4	-4.2
Systolic Blood Pressure	0.3	1.3	5.4	-1.3	-1.6	2.3	-0.8	-0.4	-0.6	-1.4	-1.3	-0.3	-1.2	0.2	-1.3	-1.2	-0.6	0.0	0.9	-1.2
Smoking Status	0.2	0.4	1.6	0.2	-0.2	1.3	0.6	-0.4	-0.3	0.1	-0.7	0.3	-0.5	-1.2	-0.3	-0.1	-0.1	-0.8	-1.0	-0.2
Allergy or Eczema	1.9	4.9	18.9	-2.4	-2.5	4.3	-0.3	-2.6	-0.4	-2.6	-2.0	-0.6	-2.2	-3.2	-2.0	-2.3	-1.7	-1.2	-1.3	-1.7
Cardiovascular Disease	0.1	0.5	1.1	-0.8	-0.5	0.1	-0.6	-1.0	-0.6	-0.8	-0.7	-0.7	-1.1	0.8	-0.6	-0.7	-0.9	-0.7	0.5	-0.5
Hypothyroidism (self reported)	0.1	0.3	1.4	-0.8	-0.3	-0.7	-0.0	0.4	-1.2	-0.6	-0.4	-0.4	-0.3	-0.4	-0.4	-0.4	-0.5	-0.6	-0.6	-0.2
Respiratory disease	0.7	1.5	11.3	-0.3	-0.6	2.0	1.4	-1.1	0.7	-0.3	-0.3	0.3	-0.4	-3.4	-0.4	-0.5	-0.4	-1.0	-1.8	-0.2
Type 2 Diabetes (T2D) (2018)	2.7	5.1	10.8	-2.1	-2.0	-0.4	-3.3	-2.8	-2.7	-2.2	-2.6	-2.5	-2.8	2.4	-2.1	-2.1	-2.3	-0.9	-0.5	-2.1
Lung FEV1/FVC ratio	0.4	2.1	10.3	0.9	0.5	0.7	-2.0	0.5	-1.6	0.7	0.4	-0.1	0.4	3.2	0.7	0.6	1.2	2.5	2.8	0.5
Lung FVC	3.1	15.8	26.1	-4.8	-4.8	2.5	-5.1	-4.9	-3.2	-4.8	-4.5	-4.2	-5.0	1.5	-4.0	-4.4	-3.1	-0.1	-1.8	-4.6
Neuroticism	0.2	0.4	1.3	0.8	0.9	-0.3	0.8	-0.3	0.0	0.8	0.7	1.1	0.2	0.8	0.6	0.7	0.3	0.0	0.6	0.3
Chronotype (morning person)	1.2	2.9	7.7	-1.7	-1.8	0.0	-2.8	-1.5	-1.4	-1.8	-1.8	-2.8	-1.9	0.7	-1.6	-1.8	-1.6	-0.2	-0.8	-1.8
Hair Pigment	0.0	1.2	4.3	0.5	0.3	1.8	2.0	1.3	1.3	0.5	0.6	2.1	0.3	-0.1	-0.1	0.4	1.5	1.7	0.2	0.3
Tanning	0.3	3.5	6.1	1.9	1.9	-1.7	1.9	2.5	1.7	2.0	1.9	2.1	2.0	-0.1	1.8	2.1	1.9	1.8	1.4	1.8
Hand grip strength (left)	0.2	0.5	1.3	-0.7	-0.7	-0.7	-0.5	-1.1	-0.6	-0.8	-0.5	-1.0	-0.5	0.7	-0.7	-0.8	-1.0	-0.7	-0.6	-0.3
Number of treatments/medications taken	0.3	0.5	1.4	-0.9	-0.6	-1.2	-0.4	-0.6	-0.3	-0.9	-0.5	-0.4	-0.6	0.8	-0.5	-0.7	-1.2	-0.7	-0.3	-0.5
Average weekly spirits intake	0.9	1.1	2.1	1.0	1.1	0.3	0.2	0.9	-1.1	1.1	1.1	0.5	1.4	0.3	1.5	1.1	1.1	1.5	1.2	1.1
Sensitivity / hurt feelings	0.4	0.6	1.7	-0.6	-0.6	-1.2	-0.3	-0.6	0.2	-0.6	-0.8	0.0	-0.9	1.3	-1.0	-0.7	-0.9	-0.8	-0.6	-1.0
Frequency of depressed mood in last 2 weeks	0.8	1.1	3.0	-1.0	-1.0	1.0	-1.0	-1.7	-1.2	-1.0	-1.1	-0.6	-1.4	0.6	-0.9	-1.1	-1.1	-0.6	-0.6	-1.4
Hearing difficulty/problems: Yes	0.4	0.5	2.0	-0.0	0.3	0.9	-1.2	-0.7	-1.0	0.0	0.0	-0.7	0.1	-0.5	0.6	0.4	0.6	1.4	1.1	0.6
Relative age of first facial hair	0.1	0.3	1.9	-0.3	-0.1	-1.0	0.8	-1.4	0.2	-0.3	0.0	0.4	-0.5	-0.2	0.1	-0.3	-0.7	0.1	-0.6	-0.1
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	2.4	-1.2	-1.3	1.1	-0.9	-1.0	-0.4	-1.2	-0.9	-1.5	-1.1	-1.5	-0.5	-1.0	-0.4	0.1	-0.9	-0.9
Ever used hormone-replacement therapy (HRT)	1.2	1.5	3.2	1.3	1.5	-0.7	0.9	0.6	0.5	1.2	1.6	0.6	0.9	-0.5	1.6	1.5	1.6	1.6	0.9	1.8
Ever had hysterectomy (womb removed)	0.2	0.3	1.1	0.5	0.7	-0.1	0.6	0.1	0.2	0.5	0.4	1.1	0.4	0.8	0.4	0.4	-0.2	-0.1	0.8	0.4
Systolic blood pressure, automated reading	0.1	0.3	2.4	0.2	-0.1	1.6	-0.2	-0.3	-0.1	0.1	-0.1	0.1	-0.4	-0.4	0.3	0.2	0.7	0.6	1.1	0.3
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	3.1	-1.1	-0.8	0.0	-1.5	-1.8	-1.6	-1.0	-1.1	-1.1	-1.0	0.6	-0.5	-0.7	-0.9	-0.4	0.2	-0.7
Angina	0.6	0.8	2.6	-0.8	-0.6	-1.3	-1.6	-0.8	-0.1	-0.8	-1.0	-1.4	-0.9	1.2	-0.5	-0.7	-0.9	-0.3	-0.3	-0.6
Medication for hormone replacement therapy	0.3	0.3	1.3	0.5	0.6	-0.1	1.1	0.1	0.7	0.4	0.4	0.7	-0.2	-1.0	0.5	0.5	0.3	0.1	-0.7	0.4
Vitamin and mineral supplements	0.4	0.6	2.1	-0.6	-1.0	0.3	-0.7	-0.2	-0.5	-0.6	-0.8	-1.5	-1.0	-0.9	-0.9	-0.8	-0.2	0.3	-1.0	-0.6
Supplements: Zinc	1.2	1.3	2.7	-1.2	-1.2	0.7	-1.2	-1.6	0.2	-1.2	-1.3	-0.9	-1.4	0.1	-1.0	-1.2	-1.5	-1.5	-0.0	-1.4
Medication: Co-codamol	0.4	0.5	1.5	-0.5	-0.6	-1.1	-1.2	-0.3	-0.8	-0.6	-0.4	-0.9	-0.6	1.2	-0.3	-0.6	-0.8	-0.1	-0.5	-0.4
Medication: Metformin	2.9	4.1	6.1	-2.1	-2.0	-0.5	-2.4	-2.4	-1.7	-2.2	-2.4	-1.7	-2.4	2.3	-2.1	-2.1	-2.5	-1.4	-0.2	-2.2
Diabetes (father)	0.5	0.6	3.2	-0.2	-0.3	-0.8	-1.8	-1.0	-0.1	-0.2	-0.8	-1.4	-0.9	1.4	-0.2	-0.3	-0.2	0.1	0.0	-0.4
Diabetes (mother)	1.6	2.1	6.6	-1.5	-1.3	0.3	-2.6	-1.3	-2.1	-1.6	-1.9	-1.5	-1.4	1.5	-1.2	-1.3	-1.1	0.3	0.1	-1.3
Severe depression (siblings)	0.7	0.8	3.6	-1.0	-1.0	1.9	-0.6	-0.8	0.5	-0.9	-1.1	-0.6	-1.1	-0.8	-0.6	-0.8	-0.3	-0.5	-0.2	-0.9
Pack years adult smoking proportion	0.5	0.8	2.5	0.9	1.0	-0.9	1.6	1.0	1.3	0.9	0.7	1.2	0.3	-0.3	0.9	1.0	0.8	0.0	0.1	0.8
Impedance of leg (right)	4.6	22.3	32.6	-5.7	-5.4	-1.1	-4.9	-4.6	-4.4	-5.7	-5.1	-4.9	-5.2	2.2	-5.6	-5.6	-5.4	-2.6	-3.1	-5.5
Leg fat-free mass (left)	4.3	22.6	32.8	5.7	5.5	-2.1	5.5	5.5	5.2	5.7	5.2	5.1	5.5	-0.5	5.2	5.5	4.6	1.0	2.4	5.3
Trunk fat percentage	0.2	0.8	5.4	0.6	0.6	-2.3	-0.0	0.3	0.5	0.7	0.5	-0.1	0.3	1.6	1.3	0.7	0.1	-0.4	0.6	0.6
Hand grip strength (right)	0.1	0.2	0.6	-0.3	-0.3	-0.6	-0.1	-0.8	0.2	-0.4	-0.3	-0.6	-0.7	0.4	-0.6	-0.4	-0.5	-0.5	-0.5	-0.1
Townsend deprivation index at recruitment	3.4	4.8	10.4	2.4	2.2	0.8	2.1	2.4	-0.5	2.5	2.0	3.2	2.6	0.1	2.5	2.4	2.4	2.2	2.4	2.1
Current tobacco smoking	0.2	0.3	2.6	0.2	-0.1	0.4	0.4	0.2	-0.6	0.2	-0.6	0.0	-0.2	-1.6	-0.3	-0.0	0.2	-0.1	-1.3	0.1
Average weekly fortified wine intake	0.2	0.2	0.8	0.3	0.5	0.0	-0.2	-0.8	-0.5	0.2	0.5	0.4	0.2	0.6	0.3	0.4	0.4	0.4	0.9	0.6
Maternal smoking around birth	0.6	0.8	4.4	0.3	0.2	2.1	-1.5	0.3	-0.3	0.3	0.2	-0.5	0.5	0.4	0.7	0.5	1.1	1.0	1.8	0.3
Fed-up feelings	0.4	0.7	2.1	0.8	1.1	-0.9	0.4	0.9	-0.7	0.9	1.0	0.8	1.0	1.4	0.9	0.9	0.4	-0.3	1.0	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.6	-0.2	-0.2	0.6	0.4	-0.1	-0.4	-0.1	-0.0	0.8	0.1	0.5	-0.1	-0.1	-0.2	0.0	-0.4	-0.5
Relative age voice broke	0.4	0.7	5.9	0.5	0.5	-2.4	1.0	-0.1	0.2	0.5	0.7	1.1	0.3	1.0	0.7	0.4	-0.1	0.5	0.7	0.4
Taking other prescription medications	0.4	0.6	4.1	-0.6	-0.6	1.6	-0.4	-0.1	-0.3	-0.6	-0.6	-0.6	-0.2	-2.0	-0.1	-0.5	-0.2	-0.8	-0.5	-0.3
Age when periods started (menarche)	0.7	1.7	9.4	-0.7	-1.0	3.1	1.1	0.8	1.3	-0.7	-0.4	0.1	-0.4	-3.0	-0.8	-0.6	0.5	0.6	-1.6	-0.6
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.9	0.2	0.1	0.1	1.4	0.1	1.1	0.1	0.2	0.6	-0.2	-0.5	0.2	-0.0	-0.4	-1.0	-0.4	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.5	-0.6	-0.7	0.8	-1.2	-0.1	0.8	-0.7	-0.9	-0.5	-0.8	1.0	-0.6	-0.7	-0.3	0.5	0.3	-0.9
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.8	-0.0	-0.3	0.3	0.2	0.5	-0.2	-0.1	-0.4	-0.4	0.0	-1.4	-0.4	-0.3	-0.3	-1.0	-1.1	-0.2
Qualifications: CSEs or equivalent	0.9	1.2	3.8	0.8	1.0	0.1	1.7	1.9	1.1	1.0	1.4	1.3	1.5	-0.2	0.5	1.0	1.0	0.2	0.8	1.0
Serious illness, injury or assault to yourself	2.5	3.0	5.7	-2.1	-1.7	-0.5	-0.7	-1.6	-0.9	-2.1	-1.8	-1.6	-1.8	-1.0	-1.8	-1.9	-2.3	-2.4	-2.0	-1.9
High blood pressure	0.3	0.8	4.5	0.3	0.6	-1.1	-1.2	-0.7	-1.1	0.2	0.1	-0.4	-0.5	2.1	0.5	0.4	-0.0	0.4	1.6	0.6
Hayfever, allergic rhinitis or eczema	1.0	2.1	11.4	-1.4	-1.4	3.4	0.0	-1.8	-0.2	-1.7	-1.2	0.1	-1.3	-2.4	-1.1	-1.3	-0.9	-0.7	-0.6	-0.8
Multivitamins +/- minerals	2.0	2.6	5.3	1.7	1.9	-0.8	1.5	1.2	0.3	1.7	1.8	2.3	1.8	1.5	1.9	1.8	1.2	0.9	2.2	1.6
Stomach or abdominal pain in last month	0.2	0.3	1.6	-0.3	0.0	-1.3	-0.6	-0.3	0.0	-0.3	-0.1	-0.7	-0.5	0.8	-0.4	-0.2	-0.6	-0.0	-0.4	0.0
Supplements: Glucosamine	0.5	0.7	4.4	0.4	0.8	-1.8	0.4	0.1	1.2	0.3	0.3	0.7	0.2	2.1	0.8	0.6	-0.2	-0.2	-0.3	0.3
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	2.2	0.2	0.2	-0.5	0.4	-0.3	1.5	0.1	0.3	-0.3	-0.4	-0.7	0.9	0.3	0.0	-0.2	-0.7	0.3
Medication: Atenolol	0.3	0.4	4.4	-0.5	-0.0	-0.1	-0.5	-0.1	0.8	-0.4	-0.1	0.3	-0.2	2.1	-0.2	-0.1	-0.3	-0.0	0.7	-0.4
Medication: Levothyroxine sodium	0.2	0.3	1.6	-0.3	0.1	-1.1	-0.5	0.4	-1.3	-0.3	-0.5	-0.7	0.0	-0.4	0.2	0.0	-0.3	-0.1	-0.6	0.3
Sitting height	1.8	12.8	21.2	4.1	4.1	-3.6	4.6	4.5	4.1	3.9	3.9	4.0	3.9	0.6	3.0	3.8	3.1	1.1	1.2	3.9
Chronic bronchitis/emphysema (father)	0.5	0.6	1.8	0.9	0.6	1.1	0.9	0.4	1.0	0.9	0.5	0.9	0.5	-1.3	0.5	0.7	0.7	0.1	0.3	0.3
High blood pressure (mother)	0.6	0.9	3.1	0.1	-0.0	1.7	-1.5	-0.5	-1.3	0.0	-0.4	-0.3	-0.2	1.1	0.1	0.1	0.6	1.8	1.6	0.1
Body mass index (BMI)	0.7	3.0	7.3	2.2	2.2	-0.4	1.1	1.4	1.7	2.3	1.7	1.1	1.4	0.4	2.7	2.3	1.8	-0.1	1.8	2.0
Impedance of leg (left)	4.3	20.7	31.3	-5.5	-5.3	-0.8	-4.7	-4.3	-4.4	-5.6	-4.8	-4.7	-4.9	2.3	-5.5	-5.4	-5.1	-2.3	-2.7	-5.3
Leg predicted mass (left)	4.2	22.4	32.5	5.6	5.5	-2.1	5.5	5.5	5.2	5.7	5.2	5.1	5.5	-0.5	5.2	5.5	4.6	1.0	2.4	5.2
Trunk fat mass	0.8	3.5	8.9	2.1	2.1	-3.0	1.6	1.8	1.9	2.2	1.9	1.3	1.7	1.4	2.5	2.1	1.2	-0.3	1.1	1.9
Waist circumference	0.2	0.9	4.8	0.8	0.7	-1.8	0.4	0.3	0.1	0.8	0.3	0.5	-0.1	2.2	1.1	0.8	-0.0	-1.1	0.9	0.5
Number of incorrect matches in round	0.7	1.2	1.9	-1.4	-1.3	-0.8	-1.1	-1.1	0.2	-1.3	-1.3	-1.4	-1.0	0.3	-0.9	-1.3	-1.3	-0.3	-1.3	-1.1
Past tobacco smoking	0.3	0.6	2.3	0.4	0.7	-0.8	-0.6	0.9	-0.4	0.5	0.8	-0.1	0.8	0.7	0.8	0.7	1.0	1.5	0.8	0.7
Alcohol usually taken with meals	0.4	0.6	7.4	0.4	0.4	-2.7	-0.0	-0.3	-0.3	0.3	0.2	-0.2	-0.1	0.8	0.5	0.3	-0.1	0.5	-0.6	0.5
Nervous feelings	0.6	1.2	2.6	-1.4	-1.3	0.8	-0.1	-1.1	0.1	-1.3	-1.0	0.2	-0.7	0.5	-1.3	-1.4	-1.6	-1.2	-0.5	-1.6
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	4.2	-0.1	-0.0	0.5	-1.1	-0.8	-1.2	-0.1	0.2	0.0	-0.2	2.1	0.3	-0.1	-0.1	0.3	1.5	-0.3
Hearing difficulty/problems with background noise	0.9	1.4	3.0	-1.2	-1.0	0.7	-1.3	-1.7	-1.0	-1.1	-1.3	-1.4	-1.3	-1.2	-1.4	-1.1	-1.0	-0.9	-1.0	-1.0
Hair/balding pattern: Pattern 2	0.4	0.5	3.0	0.3	0.3	1.7	0.5	0.3	0.2	0.4	0.6	0.6	0.1	-0.8	0.8	0.4	0.6	1.0	0.6	0.5
Had menopause	0.3	0.4	1.1	0.6	0.6	-1.0	-0.4	-1.0	-1.0	0.4	0.5	-0.4	0.0	0.9	0.6	0.5	0.2	0.7	0.4	0.7
Had other major operations	0.4	0.4	4.7	-0.2	-0.2	1.0	-0.3	-0.8	-2.2	-0.2	0.2	-0.2	-0.3	-0.2	0.0	-0.1	0.3	0.5	0.6	0.3
Forced vital capacity (FVC)	0.1	0.4	1.1	-0.8	-0.7	0.8	-0.2	-0.0	1.1	-0.8	-0.6	-0.0	-0.1	-0.1	-0.9	-0.7	-0.1	0.4	-0.9	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	2.0	0.2	-0.0	1.4	-0.4	0.5	1.4	0.1	-0.1	0.3	-0.2	0.5	0.2	0.1	0.5	0.8	1.0	-0.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.7	0.5	0.5	-1.5	1.0	-0.0	1.3	0.6	0.4	0.4	0.3	-0.6	0.3	0.4	-0.2	-1.7	-0.4	0.3
Qualifications: None of the above	0.1	0.2	1.1	-0.2	-0.3	-0.1	0.6	0.3	1.0	-0.1	-0.1	0.0	-0.3	-0.2	-0.1	-0.2	-0.2	0.2	-0.4	-0.8
Financial difficulties in last 2 years	0.3	0.3	1.5	0.1	-0.4	0.7	-0.7	0.0	-1.2	0.1	-0.2	0.1	-0.1	1.1	-0.0	-0.2	0.1	0.3	1.2	-0.4
Mouth/teeth dental problems	0.2	0.3	1.1	-0.1	0.2	0.0	0.9	0.5	0.6	-0.1	0.5	0.6	0.2	0.9	-0.6	0.0	-0.2	-1.1	0.6	-0.1
Heart attack	1.3	1.7	4.0	-1.2	-1.3	-0.1	-1.8	-1.5	-0.2	-1.3	-1.9	-1.4	-2.0	0.6	-0.9	-1.2	-1.4	-1.4	-0.3	-1.4
Allergy	0.4	1.0	7.5	0.3	0.2	-2.7	-0.8	1.1	-0.8	0.3	0.0	-0.9	0.2	2.2	-0.0	0.1	-0.0	0.4	-0.1	-0.3
Pain all over the body in last month	0.1	0.1	0.6	-0.0	-0.0	0.5	0.3	-0.1	-0.7	0.0	-0.0	-0.1	-0.2	-0.6	-0.0	-0.0	-0.2	-0.4	-0.0	-0.3
Diabetes (self-reported)	2.5	3.9	10.7	-1.3	-1.1	-1.1	-3.3	-2.9	-2.5	-1.4	-2.0	-2.0	-2.6	3.2	-1.3	-1.2	-1.8	-1.0	1.0	-1.3
Hayfever/allergic rhinitis (self-reported)	3.2	4.2	8.8	2.1	2.1	1.4	2.5	1.9	0.9	2.0	2.0	3.0	1.9	-1.1	2.0	2.2	2.3	2.2	1.4	2.5
Medication: Ramipril	0.3	0.4	1.0	0.8	0.7	-0.2	0.3	0.1	-0.1	0.8	0.3	0.8	0.1	0.6	0.7	0.7	0.5	1.0	0.8	0.5
Medication: Simvastatin	0.5	0.7	5.7	0.5	0.5	-1.6	-0.4	0.8	-0.3	0.5	0.5	0.3	0.7	2.4	0.4	0.4	0.1	0.4	1.0	0.5
Fluid intelligence score	0.3	0.6	2.2	-0.3	-0.3	-0.6	-1.2	-1.5	-1.5	-0.4	-0.5	-0.6	-0.4	1.3	-0.1	-0.4	-0.8	-0.3	0.1	-0.3
Illnesses of siblings	0.7	1.0	2.9	1.1	0.8	0.2	0.5	1.6	0.3	1.1	1.1	1.1	1.1	0.7	0.9	1.0	1.4	1.7	0.2	1.0
Neuroticism score	0.1	0.1	0.5	0.1	0.3	-0.4	0.3	-0.5	-0.1	0.2	0.1	0.5	-0.1	0.5	-0.1	0.1	-0.3	-0.7	-0.1	-0.2
Weight	2.6	13.0	19.2	4.3	4.3	-2.6	3.8	4.0	4.1	4.4	4.0	3.5	3.9	0.6	4.2	4.2	3.3	0.2	2.0	4.0
Impedance of arm (right)	2.3	10.5	17.6	-4.2	-4.1	-0.5	-3.0	-2.9	-2.8	-4.2	-3.5	-3.3	-3.4	0.5	-4.0	-4.1	-3.4	-0.5	-3.0	-3.7
Arm fat percentage (right)	0.1	0.5	2.0	0.6	0.6	-1.4	-0.1	0.5	0.7	0.7	0.3	-0.2	0.1	1.2	1.2	0.7	0.3	-0.4	0.6	0.5
Trunk fat-free mass	4.5	25.8	40.3	6.0	6.0	-3.0	6.3	6.1	5.9	6.0	5.5	5.8	5.7	-0.2	5.1	5.8	4.5	0.3	2.2	5.5
Hip circumference	1.7	7.4	18.3	3.2	3.3	-2.6	2.6	2.9	4.3	3.3	2.9	1.8	2.6	-0.2	3.1	3.2	2.3	-0.3	0.9	2.8
Time employed in main current job	1.3	1.4	3.9	1.3	1.2	-0.3	0.8	1.6	-0.3	1.2	1.3	1.0	1.3	-0.0	1.3	1.3	1.5	2.0	0.3	1.5
Alcohol intake versus 10 years previously	1.1	1.7	3.1	1.5	1.6	-0.7	1.7	1.8	1.2	1.5	1.4	1.4	1.5	-0.5	1.2	1.4	0.9	-0.2	0.7	1.4
Father’s age at death	0.3	0.5	1.2	-0.5	-0.7	0.2	0.7	-0.6	0.7	-0.5	-0.8	0.6	-0.8	1.1	-0.8	-0.6	-0.7	-0.7	-0.4	-0.7
Worrier / anxious feelings	0.1	0.2	1.2	-0.2	0.2	-0.4	0.4	-0.9	-0.0	-0.0	0.1	0.3	-0.2	0.1	0.2	0.1	-0.4	-1.1	0.2	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	1.8	-0.4	-0.1	-0.9	-0.2	-0.9	-1.3	-0.3	-0.1	-0.0	-0.4	0.9	-0.2	-0.3	-1.0	-0.7	-0.1	-0.4
Falls in the last year	0.7	1.0	3.3	-1.2	-1.0	1.1	-1.8	-1.2	-0.5	-1.1	-1.0	-1.6	-1.0	-0.4	-0.2	-0.9	-0.6	-0.3	0.6	-1.0
Hair/balding pattern: Pattern 3	0.9	1.3	3.0	-1.4	-1.4	-0.7	-0.9	-1.1	0.1	-1.3	-1.3	-0.6	-1.6	0.8	-1.7	-1.4	-0.9	-0.7	-0.6	-1.6
Number of live births	0.7	1.0	3.8	-0.3	-0.3	-1.2	-1.6	-1.3	-1.6	-0.3	-0.4	-1.2	-0.8	2.0	-0.2	-0.2	-0.3	1.2	0.7	-0.0
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	1.4	-0.4	-0.4	0.7	-0.8	0.1	0.8	-0.4	-0.4	-0.1	-0.0	1.0	-0.6	-0.4	0.3	1.2	0.2	-0.5
Pulse rate	1.9	3.2	7.1	-2.0	-2.2	0.2	-2.0	-1.7	-2.7	-2.0	-2.0	-1.8	-1.8	0.4	-1.8	-2.0	-1.6	-1.5	-0.7	-2.1
Happiness	1.4	1.7	3.8	1.5	1.4	-0.2	0.1	0.0	-1.4	1.5	1.5	0.9	1.3	0.8	2.0	1.5	1.6	1.6	1.4	1.4
Noisy workplace	0.5	0.6	1.5	-0.6	-0.9	0.2	-0.6	-0.6	-0.2	-0.7	-0.9	-0.5	-1.1	-0.6	-1.2	-0.9	-0.7	-0.8	-0.9	-1.0
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.6	0.1	0.0	-0.1	0.8	-0.7	0.5	0.1	0.2	0.6	0.1	-0.1	0.2	-0.1	-0.6	-0.8	0.3	0.0
Serious illness, injury or assault of a close relative in last 2 years	2.4	2.7	6.5	1.6	1.6	1.6	2.1	1.4	0.7	1.7	1.8	2.5	1.4	0.0	1.2	1.7	1.9	1.8	1.8	1.7
Mouth/teeth dental problems: Dentures	1.6	2.7	5.6	-1.6	-1.9	0.9	-1.5	-2.4	-1.0	-1.7	-2.0	-1.8	-2.2	-1.2	-1.3	-1.8	-1.4	0.2	-2.2	-1.6
Asthma	0.7	1.4	6.8	-0.9	-0.9	1.2	-0.8	-2.6	-0.6	-0.9	-1.0	-1.1	-1.2	-1.7	-0.5	-0.9	-1.1	-1.1	-1.2	-0.5
Medication: Ibuprofen (e.g. Nurofen)	2.9	3.7	8.9	2.1	2.2	-0.8	3.0	2.5	2.0	2.0	2.1	2.8	2.0	-0.1	1.4	2.0	1.6	0.1	1.5	1.8
Medication: Cholesterol lowering	0.9	1.3	3.2	-1.1	-1.1	-1.0	-1.8	-1.1	0.2	-1.2	-1.4	-1.6	-1.3	1.2	-0.7	-1.2	-1.3	-0.3	-0.8	-1.3
Depression (self-reported)	0.7	0.8	1.7	-1.1	-0.8	-1.3	-0.4	-1.0	0.2	-1.0	-0.8	-0.6	-0.8	0.2	-0.9	-1.0	-1.3	-0.9	-1.0	-0.9
Medication: Lansoprazole	0.3	0.4	2.8	-0.2	-0.1	1.7	-0.4	0.3	-0.4	-0.2	0.2	0.3	0.2	0.1	0.4	0.2	0.8	0.9	1.1	0.2
Prospective memory result	0.9	1.1	3.3	-1.4	-1.0	-0.7	-0.3	-1.1	-0.2	-1.2	-1.0	-0.8	-0.8	-0.1	-0.9	-1.2	-1.7	-1.8	-1.1	-1.2
Lung cancer (father)	0.3	0.3	2.0	-0.4	-0.5	-0.1	-0.2	0.1	0.0	-0.5	-0.5	-0.1	-0.0	-0.5	-0.8	-0.6	-0.5	-1.4	-0.5	-0.6
Illnesses of mother	0.5	0.6	4.2	0.2	0.5	-2.1	0.8	-0.4	0.9	0.3	0.4	-0.1	0.0	-1.1	0.2	0.3	-0.2	-0.7	-1.4	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	3.2	0.1	-0.1	1.0	0.0	1.0	0.6	-0.0	0.2	0.8	0.3	1.2	-0.3	0.1	1.0	1.8	0.7	-0.0
Pulse wave Arterial Stiffness index	0.1	0.2	0.9	0.1	0.3	-0.1	0.3	0.1	-1.0	0.1	0.2	0.4	0.6	0.7	0.3	0.3	0.2	0.1	0.1	0.5
Impedance of arm (left)	1.7	7.9	12.4	-3.5	-3.5	-0.7	-2.9	-2.6	-2.5	-3.5	-2.9	-3.0	-2.9	0.3	-3.4	-3.5	-2.8	0.1	-2.8	-3.1
Arm fat mass (right)	1.1	4.7	8.3	2.6	2.6	-2.0	1.9	2.3	2.4	2.7	2.3	1.7	2.1	1.0	2.9	2.6	1.9	-0.1	1.6	2.4
Trunk predicted mass	4.5	25.5	39.8	6.0	6.0	-3.1	6.3	6.1	5.9	5.9	5.4	5.7	5.7	-0.1	5.0	5.7	4.5	0.2	2.1	5.4
Standing height	2.1	21.0	39.4	4.9	5.0	-5.2	6.3	5.9	5.5	4.8	5.1	5.4	5.5	0.6	3.6	4.6	3.4	0.6	0.7	4.6
Length of working week for main job	0.1	0.2	0.6	0.3	0.0	-0.5	0.1	0.8	0.7	0.2	0.2	0.1	-0.0	0.7	-0.0	0.1	0.4	0.5	-0.3	-0.2
Exposure to tobacco smoke at home	0.4	0.5	1.3	0.9	0.9	-0.4	1.1	0.5	-0.8	0.9	0.3	0.9	-0.0	0.1	0.4	0.8	0.4	0.7	-0.1	0.9
Breastfed as a baby	0.3	0.4	1.2	0.4	0.6	-1.1	0.8	0.9	0.2	0.4	0.4	0.7	0.8	-0.3	0.6	0.5	-0.1	-0.6	-0.4	0.3
Tense / ‘highly strung’	0.2	0.3	1.4	-0.3	-0.2	1.1	-0.8	-1.2	-0.1	-0.3	-0.4	-0.4	-0.5	-1.0	-0.1	-0.2	-0.0	-0.1	0.1	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.0	4.2	-1.4	-1.4	1.3	-0.6	-1.2	-0.8	-1.4	-1.6	-1.2	-1.3	-1.6	-1.6	-1.6	-1.6	-2.0	-1.3	-1.5
Hair/balding pattern: Pattern 4	0.1	0.3	1.8	-0.2	-0.3	0.4	-0.9	-0.5	-1.3	-0.3	-0.4	-0.5	-0.1	0.8	-0.1	-0.3	-0.5	-0.4	0.3	-0.3
Birth weight of first child	0.4	0.8	3.5	0.7	0.7	-0.1	0.6	0.7	0.3	0.8	0.4	1.2	1.0	1.9	1.1	0.8	0.3	-0.2	1.5	0.6
Peak expiratory flow (PEF)	0.3	0.6	3.6	-0.3	-0.4	0.1	-1.9	-0.4	-0.5	-0.3	-0.4	-1.0	-0.2	1.4	-0.2	-0.3	0.1	1.3	1.1	-0.1
Pulse wave reflection index	0.2	0.3	1.8	0.1	0.3	-0.9	-0.4	-0.1	-0.7	0.1	0.3	-0.2	0.7	1.3	0.1	0.1	-0.3	-0.4	0.1	0.3
Ever highly irritable/argumentative for 2 days	2.2	2.6	7.4	-1.6	-1.5	-1.9	0.2	-1.4	-0.6	-1.7	-1.5	-0.8	-1.4	-0.1	-2.0	-1.7	-2.3	-2.7	-1.7	-1.8
Loud music exposure frequency	0.7	0.8	1.9	1.0	1.2	-0.7	0.7	0.5	-0.3	1.0	0.7	0.9	0.9	-0.9	1.2	1.0	0.7	0.7	0.3	1.4
Qualifications: O levels/GCSEs or equivalent	0.3	0.6	2.7	0.6	0.6	1.0	-0.4	0.5	-1.6	0.7	0.6	0.4	0.6	0.8	0.3	0.5	0.4	0.1	1.2	0.7
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.7	0.3	0.3	-0.8	0.4	0.1	-0.6	0.4	0.3	0.6	0.7	0.2	0.7	0.3	0.0	-0.1	0.4	0.5
Blood clot in the leg (DVT)	4.8	6.2	10.1	3.0	3.1	0.2	2.2	1.7	1.6	3.1	3.0	2.7	2.5	0.2	3.2	3.1	2.6	1.2	2.6	3.0
Medication: Paracetamol	0.3	0.5	2.6	-0.1	0.4	-1.0	0.0	-0.3	-0.1	-0.1	0.1	0.9	0.1	1.6	0.2	0.2	-0.8	-1.1	1.2	0.0
Headache pain in last month	0.2	0.3	1.3	0.3	0.6	0.4	0.8	0.6	0.3	0.3	0.2	1.1	0.2	0.6	0.2	0.6	0.2	-0.9	1.0	0.4
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	2.5	1.2	1.2	0.7	1.3	0.8	-0.2	1.2	1.6	1.6	1.5	-0.5	1.1	1.3	1.5	1.2	1.1	1.4
Glaucoma (self-reported)	2.9	3.4	8.4	1.9	2.0	-0.6	2.9	2.6	0.8	2.0	2.1	2.8	2.1	-0.2	1.7	2.1	1.6	0.3	0.9	1.8
Gout (self-reported)	0.2	0.2	0.9	0.3	0.0	0.4	-0.6	-0.7	-0.9	0.2	0.2	-0.1	0.4	-0.7	0.3	-0.1	-0.1	0.9	0.1	0.2
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.1	-1.2	-0.6	-0.5	-0.5	0.2	-1.4	-1.0	-0.9	-1.0	-0.4	-1.1	-0.6	-0.8	-0.9	-0.6	-1.4	-0.6
Medication: Amlodipine	0.2	0.3	0.7	-0.5	-0.5	-0.8	0.0	0.6	0.7	-0.5	-0.2	-0.3	-0.2	0.8	-0.6	-0.5	-0.5	-0.4	-0.4	-0.5
Medication: Ventolin 100micrograms inhaler	0.6	0.8	4.8	-0.5	-0.5	2.2	0.2	-1.6	-0.1	-0.4	-0.7	0.3	-1.2	-1.1	-0.8	-0.5	-0.5	-0.6	-0.5	-0.3
Birth weight	0.2	0.5	1.8	-0.2	-0.3	-1.3	1.1	-0.1	0.7	-0.1	-0.5	0.6	-0.4	0.9	-0.5	-0.5	-1.1	-1.3	-0.5	-0.7
Chronic bronchitis/emphysema (mother)	1.1	1.3	2.9	1.3	1.0	0.6	1.7	1.2	-0.2	1.3	1.3	1.6	1.4	-0.7	1.5	1.1	1.0	0.3	0.7	1.1
High blood pressure (siblings)	0.8	1.1	2.7	-1.3	-1.0	0.2	-0.9	-1.6	0.3	-1.3	-1.3	-1.2	-1.6	-0.2	-0.8	-1.0	-1.2	-1.1	-0.0	-1.0
Forced vital capacity (FVC), Best measure	0.1	0.3	1.2	-0.3	-0.4	0.9	0.2	0.6	0.7	-0.4	-0.2	0.5	-0.1	0.3	-0.6	-0.2	0.6	1.1	-0.4	-0.4
Body fat percentage	0.1	0.5	3.9	0.2	0.2	-2.0	-0.4	-0.0	0.2	0.3	0.1	-0.5	-0.2	1.6	0.9	0.3	-0.2	-0.8	0.5	0.1
Leg fat percentage (right)	0.2	0.7	2.6	-0.2	-0.1	-1.6	-1.0	-0.8	-0.3	-0.1	-0.4	-1.1	-0.8	1.5	0.5	-0.1	-0.8	-1.5	0.4	-0.4
Arm fat-free mass (right)	4.9	25.4	37.2	6.1	6.0	-2.5	5.9	5.8	5.2	6.1	5.7	5.5	5.8	-0.0	5.4	5.8	4.7	0.6	2.8	5.5
Exposure to tobacco smoke outside home	0.6	0.8	6.9	-0.0	-0.3	2.6	-1.2	-1.2	-1.2	-0.1	-0.4	-0.6	-0.8	0.0	-0.0	-0.2	0.2	0.2	0.6	-0.1
Comparative body size at age 10	0.2	0.5	2.6	-0.2	-0.1	-1.1	-0.5	-0.9	0.3	-0.3	-0.4	-1.2	-0.6	0.1	-0.0	-0.3	-0.5	-0.5	-1.6	-0.2
Number of full brothers	0.4	0.5	4.5	-0.5	-0.2	1.7	0.3	0.3	-0.1	-0.4	-0.2	-0.4	-0.1	-2.1	0.2	-0.1	0.3	0.1	-0.5	-0.2
Worry too long after embarrassment	0.2	0.4	1.7	-0.1	0.1	-0.8	0.7	-0.2	1.2	-0.1	-0.4	0.3	-0.7	-0.4	-0.7	-0.1	-0.5	-1.3	-0.7	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.4	0.4	0.3	0.2	1.2	0.2	0.3	0.5	0.5	0.9	0.8	-0.7	0.4	0.3	0.4	-0.1	0.4	0.2
Wheeze or whistling in the chest in last year	0.8	1.4	5.4	0.9	0.7	2.0	1.4	0.4	1.4	0.9	0.9	1.2	0.8	-2.3	1.1	1.0	1.3	0.5	0.3	1.1
Number of children fathered	1.2	1.3	3.0	-0.9	-1.1	-1.7	-0.9	-1.2	-0.4	-1.0	-0.8	-1.7	-1.2	0.9	-1.1	-1.1	-1.2	-1.5	-1.2	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.1	-0.9	-1.0	-0.2	-1.1	-0.7	0.3	-0.8	-0.8	-1.0	-0.7	0.8	-0.8	-0.9	-0.4	0.8	-0.3	-0.7
Age at first live birth	0.2	0.4	2.6	-0.5	-0.2	-1.5	-0.3	-0.4	-0.3	-0.6	-0.0	-0.3	0.3	1.6	-0.2	-0.4	-0.6	-0.2	-0.4	0.1
Pulse wave peak to peak time	0.2	0.2	2.1	0.3	0.1	-0.1	0.3	0.5	1.5	0.4	0.2	0.3	-0.1	-0.7	0.0	0.1	0.2	0.2	0.1	-0.1
Health satisfaction	0.3	0.3	0.8	0.6	0.6	0.5	-0.3	-0.1	-0.4	0.7	0.5	-0.1	0.6	-0.8	0.9	0.7	0.8	0.5	0.3	0.8
Shortness of breath walking on level ground	1.7	2.1	3.9	1.6	1.3	1.1	1.3	0.9	0.3	1.6	1.5	1.6	1.5	-0.7	1.9	1.6	1.8	2.0	1.0	1.6
Qualifications: College or University degree	0.5	1.4	5.9	-1.4	-1.1	0.9	-1.8	-2.4	-0.9	-1.4	-0.9	-1.4	-1.5	-0.1	-0.7	-1.1	-0.7	-0.1	-0.6	-0.7
Eye problems/disorders: None of the above	0.1	0.2	1.2	-0.3	-0.5	1.1	0.1	-0.2	-0.4	-0.2	-0.2	0.3	0.3	0.1	-0.2	-0.5	-0.3	0.1	0.2	-0.4
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.8	-0.2	-0.2	-1.3	0.1	0.1	0.5	-0.1	-0.2	-0.2	0.1	-0.2	0.1	-0.2	-0.7	-0.5	-0.7	-0.2
Emphysema/chronic bronchitis	1.4	1.5	5.8	0.7	0.9	-1.1	2.4	1.2	1.8	0.9	1.3	1.9	1.7	-0.8	0.8	0.8	0.1	-1.1	-0.4	0.8
Medication for pain relief, constipation, heartburn	0.3	0.5	3.2	0.6	0.1	0.0	-0.5	-0.1	-1.8	0.5	0.4	-0.5	0.2	-0.2	0.5	0.3	0.8	1.5	-0.5	0.4
Neck or shoulder pain in last month	0.3	0.4	2.4	0.1	0.4	-0.6	-0.5	0.5	-1.0	0.2	0.1	0.1	0.3	1.5	0.1	0.3	0.1	0.2	1.1	0.3
Medication: Blood pressure	1.0	1.8	4.0	-1.4	-1.2	-0.9	-1.8	-1.0	0.1	-1.4	-1.7	-2.0	-1.5	0.7	-1.2	-1.3	-1.6	-1.4	-0.9	-1.4
Angina (self-reported)	0.4	0.5	2.3	-0.6	-0.5	-0.7	-1.5	-0.7	-0.2	-0.6	-0.9	-1.2	-0.7	1.1	-0.3	-0.5	-0.7	-0.1	-0.0	-0.5
Migraine (self-reported)	0.5	0.7	2.4	-0.9	-0.6	1.4	0.6	0.1	1.5	-1.0	-0.4	0.4	-0.3	-0.6	-0.6	-0.5	-0.3	-1.5	-0.4	-0.9
Medication: Ibuprofen	3.2	3.9	9.1	1.9	2.2	-1.3	3.0	2.7	1.9	1.9	2.2	2.8	2.3	0.1	1.4	2.0	1.6	0.2	1.3	1.9
Medication: Allopurinol	0.6	0.7	1.5	-0.8	-1.1	-0.1	-0.9	-0.8	-0.5	-0.9	-0.9	-0.8	-0.4	-0.6	-0.6	-1.2	-1.2	-0.6	-1.0	-1.2
Medication: Omeprazole	1.3	1.6	5.0	-1.7	-1.2	0.5	0.6	-0.1	1.0	-1.6	-1.2	-0.4	-1.0	-1.4	-1.1	-1.2	-1.6	-2.2	-1.4	-1.2
Medication: Seretide 50 evohaler	0.4	0.4	1.5	0.6	0.6	-0.2	1.2	-0.1	0.9	0.7	0.4	0.7	0.5	-0.6	0.7	0.5	0.2	0.3	-0.9	0.9
Mean time to correctly identify matches	0.2	0.3	2.4	0.6	0.2	-0.3	0.1	-0.3	-1.2	0.4	0.2	0.5	0.0	-0.1	-0.0	0.3	0.5	1.6	-0.2	0.3
Heart disease (mother)	0.2	0.2	1.3	0.1	-0.1	1.1	-0.3	-0.4	0.5	-0.0	-0.4	-0.2	-0.6	0.1	0.4	-0.0	-0.1	0.3	0.6	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	4.3	-0.7	-0.7	0.0	-0.9	-1.8	-2.1	-0.7	-0.9	-1.2	-1.1	-0.1	-0.6	-0.8	-0.8	0.2	-0.4	-0.6
Whole body fat mass	0.7	3.0	7.4	1.9	2.0	-2.7	1.3	1.6	1.7	2.0	1.7	1.1	1.5	1.5	2.4	1.9	1.1	-0.6	1.1	1.7
Leg fat mass (right)	0.4	1.5	4.8	1.3	1.3	-2.2	0.5	0.9	1.3	1.4	0.9	0.3	0.7	1.6	1.8	1.3	0.5	-1.1	0.9	1.0
Arm predicted mass (right)	4.9	25.3	37.0	6.1	6.0	-2.3	5.8	5.8	5.2	6.0	5.7	5.5	5.8	0.1	5.4	5.9	4.8	0.5	3.0	5.5
Pulse rate, automated reading	0.6	1.9	4.9	-1.2	-1.4	-0.8	-0.8	-0.8	-2.2	-1.3	-1.7	-1.0	-1.6	0.5	-1.6	-1.5	-1.5	-1.1	-1.5	-1.5
Alcohol intake frequency.	0.1	0.1	1.2	0.3	0.4	-1.1	0.2	0.4	0.3	0.3	-0.1	-0.1	0.0	0.4	0.2	0.3	-0.1	-0.3	-0.0	0.1
Comparative height size at age 10	1.0	5.5	9.5	2.8	2.6	-2.9	2.9	2.6	3.1	2.6	2.6	2.4	2.8	0.4	2.2	2.4	1.6	-0.1	0.3	2.3
Number of full sisters	0.2	0.2	1.1	0.6	0.4	0.2	0.2	1.1	0.3	0.5	0.3	0.4	0.3	-0.0	-0.1	0.4	0.5	0.5	0.2	0.4
Suffer from ‘nerves’	0.4	0.6	2.0	-0.8	-0.7	0.5	-0.4	-1.4	-1.3	-0.8	-0.5	-0.2	-0.7	0.2	-0.5	-0.8	-1.1	-0.3	-0.3	-0.7
Overall health rating	0.3	0.6	1.5	-0.8	-0.9	0.8	-0.5	-0.5	-0.5	-0.7	-0.8	-0.8	-0.4	-1.2	-0.7	-0.8	-0.6	-0.4	-1.2	-0.7
Chest pain or discomfort	0.3	0.5	2.2	0.4	0.5	0.1	0.3	0.6	-0.4	0.5	0.9	0.5	1.1	-0.4	0.8	0.6	0.5	1.5	0.8	0.8
Had major operations	0.9	1.1	4.3	-0.9	-0.6	0.4	0.2	-0.6	1.6	-0.9	-1.1	-0.6	-1.2	-2.1	-0.6	-0.7	-0.8	-1.2	-1.5	-0.7
Age at last live birth	0.4	0.5	1.3	-1.0	-0.8	-0.4	-0.7	-0.8	-0.7	-1.0	-0.7	-0.7	-0.6	1.1	-0.6	-0.8	-0.8	0.1	-0.7	-0.4
Family relationship satisfaction	2.5	3.1	6.2	1.7	1.8	1.1	0.7	1.5	-0.2	1.9	2.0	1.3	2.5	-0.8	2.5	2.0	2.2	2.2	1.9	1.9
Leg pain on walking	0.2	0.3	2.8	-0.0	0.0	1.1	0.1	-0.1	-0.3	-0.0	0.1	-0.4	0.4	-1.7	0.1	0.1	-0.0	-0.8	-0.1	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.4	0.7	0.7	-0.1	0.4	0.8	-1.2	0.7	0.3	0.9	0.5	0.2	0.5	0.6	0.6	1.1	0.3	0.8
Commuting to job workplace: Car/motor vehicle	1.9	2.2	8.0	-0.9	-1.2	-1.6	-2.8	-1.9	-0.6	-1.0	-1.6	-2.6	-1.8	0.6	-1.2	-1.2	-1.2	-0.8	-0.5	-1.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.9	0.8	0.6	-0.7	-0.3	0.9	0.3	0.7	0.5	-0.4	0.1	-0.9	0.3	0.7	1.3	1.4	-0.2	0.7
Medication: Aspirin	0.4	0.5	2.6	-0.4	-0.1	-0.5	-1.6	-0.7	0.2	-0.2	-0.4	-1.0	-0.1	1.4	0.0	-0.2	-0.2	0.2	1.2	-0.1
Supplements: Vitamin C	0.2	0.2	0.7	-0.6	-0.3	0.0	-0.8	-0.8	0.1	-0.7	-0.1	-0.6	-0.4	0.3	0.1	-0.3	-0.3	-0.2	0.3	-0.3
Knee pain experienced in last month	0.5	0.8	6.0	0.2	-0.0	2.4	0.4	0.8	1.6	0.2	0.6	0.6	0.6	-1.4	-0.1	0.1	0.7	0.4	-0.2	0.0
Hypertension (Self-reported)	0.3	0.8	4.2	-0.2	0.1	-1.2	-1.4	-0.9	-1.1	-0.2	-0.3	-0.8	-0.7	2.1	0.1	-0.0	-0.5	-0.3	1.2	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	1.7	0.6	0.9	0.2	0.5	0.1	1.3	0.7	0.7	0.6	0.4	-0.6	1.1	0.9	0.8	0.1	1.1	0.7
Illnesses of father: Heart disease	0.7	1.0	3.7	-1.1	-0.8	0.1	-1.0	-0.7	0.6	-1.1	-1.3	-1.3	-1.9	0.2	-1.0	-0.9	-1.0	-0.5	-1.0	-0.8
Illnesses of siblings: Diabetes	0.1	0.2	0.8	-0.0	-0.1	0.0	0.3	-0.2	-0.8	-0.1	-0.3	0.6	-0.2	0.9	-0.1	-0.1	-0.3	-0.4	0.9	-0.1
Smoking status: Previous	0.7	1.0	2.7	-1.0	-1.1	1.2	-0.2	-1.4	0.4	-1.0	-1.1	-0.6	-1.1	-0.6	-0.9	-1.1	-1.3	-1.6	-0.6	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	5.6	1.2	1.4	-0.7	1.4	1.3	2.4	1.3	1.3	1.4	1.1	-0.1	0.9	1.4	1.5	0.9	0.3	1.3
Whole body fat-free mass	4.8	27.3	39.1	6.2	6.2	-2.6	6.2	6.1	5.7	6.2	5.8	5.8	6.0	-0.2	5.5	6.0	4.9	0.6	2.6	5.7
Leg fat-free mass (right)	4.6	24.6	35.0	5.9	5.7	-1.7	5.8	5.7	5.4	5.9	5.5	5.4	5.8	-0.6	5.4	5.7	4.9	1.3	2.7	5.5
Arm fat percentage (left)	0.2	0.8	2.4	1.0	1.0	-1.4	0.2	0.8	1.0	1.1	0.7	0.1	0.5	1.0	1.6	1.1	0.7	-0.1	0.6	0.9
Average weekly red wine intake	1.5	2.3	3.5	1.6	1.6	-1.5	1.0	0.3	-0.6	1.6	1.7	1.9	1.2	1.8	1.6	1.6	1.3	1.9	1.8	1.6
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.7	-0.1	-0.2	0.2	1.2	-0.1	1.3	-0.2	-0.2	0.5	-0.8	-1.2	-0.2	-0.1	0.0	-0.4	-0.8	-0.0
Mood swings	0.1	0.3	1.3	0.0	0.4	-0.8	0.1	-0.4	-0.7	0.1	0.5	0.5	0.4	1.1	0.0	0.1	-0.4	-0.9	-0.0	-0.2
Loneliness, isolation	0.4	0.5	1.8	0.7	0.7	-0.6	-0.6	0.1	-0.7	0.6	0.6	0.3	0.9	1.1	0.9	0.5	0.3	1.3	0.5	0.1
Long-standing illness, disability or infirmity	0.1	0.2	0.7	0.4	0.5	-0.5	0.1	0.3	-0.4	0.4	0.3	0.0	0.2	-0.4	0.6	0.5	0.3	0.8	-0.2	0.7
Ever had bowel cancer screening	1.7	2.0	4.0	1.4	1.8	-1.7	0.2	0.9	-0.2	1.4	1.4	0.8	1.7	0.6	1.8	1.8	1.3	1.1	1.9	2.0
Diabetes diagnosed by doctor	2.5	4.1	10.7	-1.6	-1.4	-0.8	-3.3	-3.0	-2.7	-1.6	-2.3	-2.1	-2.6	2.6	-1.4	-1.5	-2.0	-1.0	0.5	-1.6
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	1.5	0.9	0.7	-0.8	0.7	1.2	0.5	0.9	0.7	0.6	0.5	0.8	0.3	0.7	0.7	0.9	0.6	0.8
Friendships satisfaction	0.7	0.9	2.4	0.8	1.2	-0.8	-0.0	0.5	-0.3	0.9	1.1	0.6	1.2	1.0	1.6	1.1	0.7	0.7	1.3	0.8
Qualifications: nursing, teaching	0.3	0.4	3.2	-0.1	0.0	-0.7	-1.1	-0.3	-0.7	-0.1	-0.3	-0.8	-0.5	1.8	0.1	0.0	-0.2	-0.4	0.7	0.1
Commuting to job workplace: Walk	0.6	0.6	2.9	0.4	0.7	0.5	1.7	0.3	0.7	0.5	0.5	1.1	0.3	-1.0	0.9	0.7	0.4	0.6	-0.6	1.1
Eye problems/disorders: Cataract	0.4	0.4	1.8	0.1	0.5	-1.4	-1.2	-0.9	-0.5	0.1	0.2	-0.7	0.0	0.8	0.8	0.4	-0.1	-0.4	0.8	0.6
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.8	0.0	0.2	-0.4	-1.1	-0.8	-1.4	0.1	-0.1	-0.7	-0.1	-0.1	0.6	0.1	-0.3	0.2	0.3	0.4
Medication for cholesterol	1.2	1.8	7.8	-1.0	-1.2	1.3	-0.8	-0.7	0.7	-1.0	-1.3	-1.5	-0.4	-2.8	-1.4	-1.3	-0.9	-1.3	-1.9	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.6	2.6	-1.6	-1.5	0.6	-1.1	-0.8	-1.1	-1.6	-1.5	-1.4	-1.2	-0.4	-1.6	-1.4	-1.5	-1.2	-1.2	-1.4
Back pain experienced in last month	1.6	2.3	4.4	1.9	2.1	0.5	1.4	1.9	0.8	1.9	1.5	1.6	1.8	-0.8	1.4	2.0	1.6	0.2	0.8	2.0
Mineral and other dietary supplements	0.2	0.3	2.2	0.1	-0.3	1.4	0.3	-0.1	-0.2	0.1	-0.2	-0.2	-0.5	-1.5	-0.4	-0.1	0.3	-0.1	0.1	0.1
Breast cancer (self-reported)	0.6	0.7	1.8	0.7	0.8	-1.4	0.6	0.6	1.2	0.8	1.1	0.4	0.8	0.1	1.1	0.9	0.8	1.0	0.8	0.9
Asthma (self-reported)	0.6	1.2	6.2	-0.8	-0.8	1.3	-0.6	-2.5	-0.5	-0.8	-1.0	-0.9	-1.2	-1.8	-0.5	-0.8	-1.0	-0.9	-1.2	-0.4
Osteoporosis (self-reported)	0.7	0.9	1.6	-1.2	-1.1	0.4	-0.6	-0.8	-0.2	-1.1	-1.0	-0.8	-0.7	-1.1	-1.3	-1.1	-0.9	-1.1	-0.8	-0.9
Osteoarthritis (self-reported)	1.6	2.0	5.9	1.2	1.4	-0.5	0.2	1.3	1.0	1.4	1.7	1.0	1.2	1.8	1.4	1.6	1.9	1.4	2.4	1.2
Medication: Aspirin	0.6	0.8	3.0	-1.0	-0.8	-0.2	-1.7	-1.0	0.2	-0.9	-1.0	-1.4	-0.7	1.1	-0.7	-0.8	-0.8	-0.3	0.4	-0.6
Medication: Gliclazide	1.4	1.6	8.9	-0.6	-0.9	0.4	-1.8	-2.3	-3.0	-0.7	-1.4	-1.0	-1.3	0.9	-0.8	-0.9	-0.8	-0.2	0.5	-0.8
Illnesses of father: None of the above (group 1)	0.4	0.5	2.2	0.4	0.1	0.8	1.4	0.3	-1.0	0.3	0.9	1.5	1.2	-0.3	0.7	0.2	0.3	0.3	0.4	0.1
Smoking status: Current	0.2	0.4	2.1	0.5	0.2	0.5	1.0	0.6	-0.5	0.5	-0.2	0.6	0.2	-1.4	0.0	0.3	0.4	0.1	-0.9	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	4.4	-1.1	-1.2	1.6	-2.1	-0.4	-2.1	-1.2	-1.2	-1.0	-0.6	1.1	-0.9	-1.0	0.0	1.6	0.1	-0.9
Whole body water mass	4.8	27.7	39.7	6.2	6.2	-2.5	6.3	6.2	5.8	6.2	5.8	5.9	6.1	-0.2	5.6	6.0	4.9	0.7	2.7	5.7
Leg predicted mass (right)	4.6	24.6	35.2	5.9	5.7	-1.7	5.7	5.8	5.3	5.9	5.5	5.4	5.8	-0.5	5.4	5.7	4.9	1.3	2.7	5.5
Arm fat mass (left)	1.1	4.4	7.8	2.5	2.5	-2.0	2.0	2.3	2.4	2.6	2.2	1.7	2.0	0.8	2.8	2.5	1.8	-0.1	1.3	2.3
Number of self-reported non-cancer illnesses	0.9	1.5	5.2	-1.4	-1.1	0.5	-1.7	-2.3	-1.4	-1.5	-1.2	-0.9	-1.2	0.8	-0.6	-1.2	-1.4	-0.7	0.5	-0.9
Average weekly champagne plus white wine intake	0.4	0.5	1.6	-0.5	-0.5	-1.3	-1.0	-0.8	0.2	-0.5	-0.7	-1.1	-0.7	-0.1	-0.4	-0.5	-0.7	-1.2	-0.2	-0.6
Miserableness	0.7	1.2	2.3	1.3	1.5	-0.1	0.7	0.1	-0.6	1.3	1.1	1.5	1.0	1.3	1.3	1.3	0.8	0.4	1.4	1.2
Guilty feelings	0.2	0.3	2.0	-0.4	-0.4	0.3	-0.1	-0.1	0.6	-0.4	-0.4	-0.1	-0.5	0.5	-0.7	-0.4	-0.6	-1.4	0.1	-0.6
Wears glasses or contact lenses	1.6	1.8	5.7	1.6	1.7	-2.4	0.1	0.1	0.9	1.5	1.5	-0.0	0.9	0.4	1.4	1.6	1.3	2.0	0.2	1.9
Ever taken oral contraceptive pill	0.6	0.6	3.8	-0.1	-0.1	-0.4	0.8	1.9	1.3	-0.1	-0.1	0.5	0.3	-0.5	-1.3	-0.3	0.1	-0.1	-1.5	-0.3
Hearing aid user	1.1	1.2	6.8	-0.8	-0.9	1.8	-0.1	-0.3	0.3	-0.9	-1.1	-0.9	-0.9	-2.6	-1.1	-0.8	-0.5	-0.7	-1.5	-0.7
Mother’s age at death	0.3	0.4	2.2	-0.5	-0.6	-0.1	-1.5	0.1	0.2	-0.5	-0.5	-1.1	-0.3	1.1	-0.3	-0.5	-0.3	-0.4	0.4	-0.6
Financial situation satisfaction	0.4	0.5	2.6	-0.6	-0.5	-0.5	-1.3	-1.1	0.2	-0.5	-0.3	-1.6	-0.3	-0.8	0.2	-0.6	-0.8	-0.5	-0.2	-0.2
Tinnitus: Yes, now most or all of the time	0.3	0.4	3.0	0.3	0.6	-0.7	-0.3	-0.5	-1.7	0.2	-0.1	-0.3	-0.3	-0.0	0.2	0.6	0.4	0.5	0.2	0.8
Commuting to job workplace: Public transport	2.6	3.1	6.1	1.6	1.7	1.3	2.5	1.7	1.2	1.5	1.7	2.4	1.9	-2.0	1.8	1.9	2.2	1.1	0.6	1.8
Eye problems/disorders: Glaucoma	1.6	1.9	5.7	1.5	1.5	-0.3	2.2	2.4	0.7	1.5	1.5	1.7	1.5	-0.4	0.8	1.5	1.4	0.3	0.2	1.3
Medication: Blood pressure	0.6	1.2	5.9	0.6	0.9	-1.4	0.6	0.7	-0.5	0.6	1.2	1.0	0.6	2.4	1.0	0.9	0.5	0.9	1.9	0.9
Pain type(s) experienced in last month: Hip pain	0.1	0.2	1.5	-0.3	-0.3	1.2	0.2	-0.7	-0.0	-0.3	-0.1	0.3	-0.2	0.3	0.1	-0.1	-0.3	-0.5	0.4	0.1
Supplements: Fish oil (including cod liver oil)	0.4	0.5	3.5	-0.3	-0.3	-0.3	-1.2	-0.6	-1.0	-0.4	-0.3	-0.1	-0.3	1.9	-0.1	-0.3	-0.4	0.5	0.7	-0.6
High cholesterol (Self-reported)	0.4	0.7	5.9	-0.1	-0.1	-2.2	-0.4	0.3	0.1	-0.1	0.2	-0.0	0.2	2.4	0.1	-0.0	-0.1	0.6	0.8	0.0
Medication: Bendroflumethiazide	1.1	1.6	3.4	1.1	1.3	0.2	0.5	1.5	-0.1	1.1	1.9	1.0	1.5	1.2	1.4	1.3	1.4	1.4	1.8	1.4
Medication: Paracetamol	0.4	0.6	3.6	-0.6	-0.1	-0.6	-0.1	-0.8	-0.3	-0.6	-0.6	0.6	-0.4	1.2	-0.6	-0.4	-1.2	-1.9	0.6	-0.7
Medication: Lisinopril	0.2	0.2	1.1	-0.1	0.1	0.5	-0.9	-0.6	0.4	-0.1	-0.4	-1.1	-0.3	-0.7	0.6	0.1	0.1	-0.1	0.1	0.2
Medication: Atorvastatin	2.1	2.6	6.7	-1.9	-1.6	-0.6	-1.9	-2.1	-0.0	-1.9	-1.8	-2.6	-2.4	-0.1	-1.1	-1.6	-1.2	-0.3	-1.5	-1.6
Illnesses of father: High blood pressure	0.3	0.4	1.3	-0.2	0.3	-0.8	-0.6	-1.1	-0.7	-0.1	-0.2	-0.6	-0.5	1.1	0.1	0.0	-0.6	0.1	1.0	0.5
Alcohol drinker status: Never	2.2	2.6	4.9	-2.2	-1.8	-0.2	-1.6	-1.0	-0.7	-2.1	-1.7	-2.0	-1.4	0.7	-1.9	-1.9	-1.8	-1.3	-1.1	-2.2
Ever smoked	0.6	1.1	2.3	-0.8	-1.2	0.7	0.1	-1.0	-0.2	-0.8	-1.4	-0.4	-1.4	-0.5	-1.4	-1.2	-1.3	-1.5	-1.4	-1.1
Basal metabolic rate	4.3	24.0	34.2	5.8	5.8	-2.5	5.8	5.7	5.4	5.8	5.4	5.3	5.6	-0.1	5.3	5.7	4.6	0.6	2.5	5.3
Leg fat percentage (left)	0.2	0.6	2.6	-0.1	-0.0	-1.4	-0.8	-0.6	-0.1	0.0	-0.1	-0.9	-0.5	1.6	0.7	0.1	-0.5	-1.3	0.6	-0.2
Arm fat-free mass (left)	4.6	23.2	32.7	5.7	5.7	-2.3	5.7	5.5	5.0	5.7	5.4	5.3	5.5	0.2	5.2	5.6	4.3	0.1	3.0	5.2
Number of operations (self-reported)	0.2	0.3	0.9	-0.6	-0.5	-0.4	0.1	-0.5	0.1	-0.7	-0.2	-0.8	-0.8	-0.9	-0.2	-0.5	-0.5	-0.8	-0.9	-0.2
Average weekly beer plus cider intake	1.9	2.8	6.8	1.9	1.9	0.4	1.1	1.2	-0.5	1.9	1.4	2.4	1.6	1.6	1.6	2.0	1.8	1.5	2.6	1.6
Irritability	0.2	0.3	1.3	-0.2	-0.2	-0.1	-0.8	-0.9	-1.0	-0.2	-0.4	-0.4	-0.3	0.0	-0.1	-0.4	-0.7	-1.1	-0.3	-0.5
Risk taking	0.3	0.4	1.6	-0.1	-0.1	0.5	-1.3	-1.3	0.3	-0.1	-0.8	-0.8	-0.8	-0.4	-0.0	-0.1	-0.3	-0.6	0.8	-0.3
Ever had prostate specific antigen (PSA) test	1.8	2.1	4.9	-1.5	-1.5	0.2	-0.8	-1.0	-0.0	-1.5	-1.7	-1.3	-1.6	-0.1	-1.7	-1.6	-1.8	-2.2	-1.9	-1.7
Fractured/broken bones in last 5 years	0.2	0.3	0.7	0.4	0.6	-0.9	-0.4	-0.7	-0.5	0.4	0.5	0.1	0.6	0.8	0.6	0.5	0.2	0.3	0.7	0.7
Age started oral contraceptive pill	0.9	1.1	3.4	1.0	1.0	-0.7	-0.4	0.3	0.1	0.8	1.0	0.6	0.5	1.8	1.1	1.1	1.3	1.4	1.8	1.0
Diastolic blood pressure, automated reading	0.3	0.8	1.8	0.8	0.5	0.7	1.3	1.2	1.2	0.8	0.8	0.9	0.9	-1.4	0.8	0.7	1.1	-0.0	0.3	0.7
Ever depressed for a whole week	0.5	0.7	2.5	-0.8	-0.7	-1.1	-0.6	-0.2	0.8	-0.7	-0.8	-0.7	-0.4	-0.1	-0.8	-0.8	-1.2	-1.6	-0.5	-0.9
Unable to work because of sickness or disability	0.5	0.7	2.7	-0.7	-1.0	0.4	-0.4	-0.2	0.4	-0.7	-1.0	-1.0	-0.9	-1.6	-0.7	-0.8	-0.5	-0.8	-1.0	-1.0
Commuting to job workplace: Cycle	0.8	1.0	5.2	0.2	0.2	0.5	2.3	0.8	1.5	0.2	0.6	0.9	0.6	-1.8	-0.0	0.1	-0.1	-1.2	-1.1	0.1
Myopia	0.3	0.5	1.7	-0.9	-0.6	-0.5	-1.3	-1.2	-0.6	-0.8	-0.7	-1.1	-0.5	0.3	-0.2	-0.5	-0.7	-0.1	0.2	-0.3
Vascular/heart problems diagnosed by doctor	0.4	1.0	5.0	0.3	-0.0	1.0	1.7	1.3	1.2	0.4	0.5	1.0	1.1	-2.2	-0.0	0.1	0.6	0.2	-1.4	-0.1
Cholesterol lowering medication	0.7	1.1	6.5	0.6	0.7	-1.1	0.4	0.4	-0.8	0.6	0.8	0.9	0.3	2.5	0.7	0.8	0.7	0.9	2.0	0.9
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	2.7	-1.4	-1.0	1.0	0.2	-0.2	0.8	-1.3	-0.8	-0.4	-0.7	-1.4	-0.6	-0.9	-1.2	-1.6	-1.1	-0.8
Pain experienced in last month	0.2	0.4	1.7	-0.3	-0.5	-1.2	0.0	-0.0	-1.3	-0.3	0.2	-0.0	0.2	1.2	-0.0	-0.4	-0.1	1.0	-0.1	-0.2
Supplements: Calcium	1.4	1.6	4.4	-1.5	-1.3	-0.1	0.1	-1.4	0.1	-1.4	-1.3	-0.4	-1.1	-0.7	-1.4	-1.4	-1.9	-2.1	-1.4	-1.3
Basal cell carcinoma (self-reported)	0.1	0.1	0.5	-0.2	-0.1	-0.7	0.7	0.5	0.2	-0.1	0.0	0.4	0.1	0.2	0.1	-0.1	-0.4	-0.2	-0.1	-0.1
Heart attack/myocardial infarction (self-reported)	1.1	1.5	3.6	-1.1	-1.2	-0.2	-1.7	-1.4	-0.1	-1.2	-1.8	-1.4	-1.9	0.5	-0.8	-1.1	-1.3	-1.3	-0.4	-1.3
Deep venous thrombosis (DVT) (self-reported)	3.7	4.8	7.8	2.5	2.6	0.5	2.0	1.5	1.9	2.7	2.7	2.4	2.1	0.0	2.8	2.7	2.3	1.1	2.3	2.6
Heart disease (siblings)	2.6	3.2	7.1	-1.8	-1.4	-1.0	-2.5	-2.7	-2.4	-1.8	-1.6	-2.6	-1.7	0.6	-1.3	-1.7	-2.2	-1.4	-0.5	-1.4
Alcohol drinker status: Previous	0.3	0.3	0.9	-0.4	-0.2	-0.9	0.5	-0.3	0.9	-0.4	-0.5	-0.0	-0.5	-0.7	-0.3	-0.3	-0.7	-1.0	-0.5	-0.3
Pack years of smoking	0.6	0.9	3.0	0.9	1.0	-0.9	1.7	1.0	1.5	0.9	0.8	1.2	0.4	-0.4	1.0	1.0	0.8	-0.0	0.1	0.8
Impedance of whole body	2.6	13.1	20.9	-4.6	-4.4	-0.8	-3.6	-3.3	-3.5	-4.6	-3.7	-3.8	-3.8	1.1	-4.5	-4.5	-3.9	-1.0	-2.8	-4.2
Leg fat mass (left)	0.5	1.8	4.6	1.5	1.5	-2.1	0.8	1.2	1.5	1.6	1.2	0.5	1.0	1.5	1.9	1.5	0.8	-1.0	1.1	1.2
Arm predicted mass (left)	4.6	23.4	32.8	5.7	5.7	-2.4	5.7	5.6	4.9	5.7	5.5	5.4	5.6	0.4	5.2	5.6	4.4	0.2	3.0	5.2