TWAS hub - NUDT6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0440	0.0200	6.3e-03	0.042	0.004	0.021	0.014	0.023	7.1e-06	1.0e-01	1.1e-03	0.00670	6.5e-04
2	GTEx	Artery Tibial	0.0799	0.0384	8.2e-03	0.075	NA	0.051	NA	0.053	1.7e-06	NA	6.9e-05	NA	5.6e-05
3	GTEx	Brain Cerebellar Hemisphere	0.3200	0.0930	3.0e-04	0.072	NA	0.165	NA	0.112	6.5e-03	NA	5.0e-05	NA	8.6e-04
4	GTEx	Breast Mammary Tissue	0.2500	0.0830	2.2e-04	0.105	NA	0.052	NA	0.084	5.0e-06	NA	1.2e-03	NA	4.2e-05
5	GTEx	Breast Mammary Tissue (Male)	0.2898	0.1284	9.7e-03	-0.004	NA	-0.012	NA	-0.001	4.1e-01	NA	7.8e-01	NA	3.5e-01
6	GTEx	Breast Mammary Tissue (Female)	0.3009	0.1082	7.5e-03	-0.010	NA	0.003	NA	-0.009	9.0e-01	NA	2.5e-01	NA	7.8e-01
7	GTEx	Muscle Skeletal	0.1468	0.0391	4.2e-08	0.118	NA	0.099	NA	0.107	1.4e-11	NA	6.2e-10	NA	1.1e-10
8	GTEx	Nerve Tibial	0.1128	0.0417	9.9e-04	0.075	NA	0.037	NA	0.049	5.3e-06	NA	1.2e-03	NA	2.1e-04
9	GTEx	Skin Not Sun Exposed Suprapubic	0.0720	0.0330	5.6e-03	0.024	NA	0.017	NA	0.026	1.7e-02	NA	3.8e-02	NA	1.5e-02
10	GTEx	Skin Sun Exposed Lower leg	0.1110	0.0380	1.3e-04	0.078	NA	0.063	NA	0.077	5.3e-07	NA	6.0e-06	NA	6.2e-07
11	GTEx	Thyroid	0.0650	0.0290	8.9e-04	0.032	NA	0.052	NA	0.053	1.7e-03	NA	7.5e-05	NA	6.9e-05
12	ROSMAP	Brain Pre-frontal Cortex	0.0412	0.0185	6.6e-03	0.035	0.023	0.027	0.024	0.026	2.1e-05	5.7e-04	2.0e-04	0.00044	2.6e-04
13	TCGA	Breast Invasive Carcinoma	0.0217	0.0112	2.3e-03	0.018	0.006	0.003	NA	0.009	1.2e-04	2.1e-02	7.5e-02	NA	5.4e-03
14	TCGA	Brain Lower Grade Glioma	0.0506	0.0207	2.0e-05	0.058	0.044	0.041	NA	0.050	3.3e-07	8.2e-06	1.7e-05	NA	2.0e-06
15	TCGA	Lung Adenocarcinoma	0.0414	0.0212	4.3e-03	0.006	0.007	0.007	NA	0.002	6.0e-02	4.5e-02	4.5e-02	NA	1.9e-01
16	TCGA	Pheochromocytoma and Paraganglioma	0.1300	0.0730	4.2e-03	0.006	0.034	-0.005	NA	0.007	1.8e-01	1.6e-02	5.7e-01	NA	1.7e-01
17	TCGA	Prostate Adenocarcinoma	0.1008	0.0351	1.3e-07	0.071	0.061	0.066	NA	0.069	6.9e-08	5.5e-07	1.7e-07	NA	1.0e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Arm fat-free mass (right)	4.9	25.4	37.2	6.1	6.0	-2.5	5.9	5.8	5.2	6.1	5.7	5.5	5.8	-0.0	5.4	5.8	4.7	0.6	2.8	5.5
Arm predicted mass (right)	4.9	25.3	37.0	6.1	6.0	-2.3	5.8	5.8	5.2	6.0	5.7	5.5	5.8	0.1	5.4	5.9	4.8	0.5	3.0	5.5
Lupus	4.8	7.2	13.3	-3.1	-3.0	0.7	-1.1	-2.1	-0.3	-3.2	-3.0	-2.4	-2.4	-2.0	-3.3	-3.2	-3.1	-3.1	-3.7	-3.1
Blood clot in the leg (DVT)	4.8	6.2	10.1	3.0	3.1	0.2	2.2	1.7	1.6	3.1	3.0	2.7	2.5	0.2	3.2	3.1	2.6	1.2	2.6	3.0
Whole body fat-free mass	4.8	27.3	39.1	6.2	6.2	-2.6	6.2	6.1	5.7	6.2	5.8	5.8	6.0	-0.2	5.5	6.0	4.9	0.6	2.6	5.7
Whole body water mass	4.8	27.7	39.7	6.2	6.2	-2.5	6.3	6.2	5.8	6.2	5.8	5.9	6.1	-0.2	5.6	6.0	4.9	0.7	2.7	5.7
Impedance of leg (right)	4.6	22.3	32.6	-5.7	-5.4	-1.1	-4.9	-4.6	-4.4	-5.7	-5.1	-4.9	-5.2	2.2	-5.6	-5.6	-5.4	-2.6	-3.1	-5.5
Leg fat-free mass (right)	4.6	24.6	35.0	5.9	5.7	-1.7	5.8	5.7	5.4	5.9	5.5	5.4	5.8	-0.6	5.4	5.7	4.9	1.3	2.7	5.5
Leg predicted mass (right)	4.6	24.6	35.2	5.9	5.7	-1.7	5.7	5.8	5.3	5.9	5.5	5.4	5.8	-0.5	5.4	5.7	4.9	1.3	2.7	5.5
Arm fat-free mass (left)	4.6	23.2	32.7	5.7	5.7	-2.3	5.7	5.5	5.0	5.7	5.4	5.3	5.5	0.2	5.2	5.6	4.3	0.1	3.0	5.2
Arm predicted mass (left)	4.6	23.4	32.8	5.7	5.7	-2.4	5.7	5.6	4.9	5.7	5.5	5.4	5.6	0.4	5.2	5.6	4.4	0.2	3.0	5.2
Trunk fat-free mass	4.5	25.8	40.3	6.0	6.0	-3.0	6.3	6.1	5.9	6.0	5.5	5.8	5.7	-0.2	5.1	5.8	4.5	0.3	2.2	5.5
Trunk predicted mass	4.5	25.5	39.8	6.0	6.0	-3.1	6.3	6.1	5.9	5.9	5.4	5.7	5.7	-0.1	5.0	5.7	4.5	0.2	2.1	5.4
Leg fat-free mass (left)	4.3	22.6	32.8	5.7	5.5	-2.1	5.5	5.5	5.2	5.7	5.2	5.1	5.5	-0.5	5.2	5.5	4.6	1.0	2.4	5.3
Impedance of leg (left)	4.3	20.7	31.3	-5.5	-5.3	-0.8	-4.7	-4.3	-4.4	-5.6	-4.8	-4.7	-4.9	2.3	-5.5	-5.4	-5.1	-2.3	-2.7	-5.3
Basal metabolic rate	4.3	24.0	34.2	5.8	5.8	-2.5	5.8	5.7	5.4	5.8	5.4	5.3	5.6	-0.1	5.3	5.7	4.6	0.6	2.5	5.3
Leg predicted mass (left)	4.2	22.4	32.5	5.6	5.5	-2.1	5.5	5.5	5.2	5.7	5.2	5.1	5.5	-0.5	5.2	5.5	4.6	1.0	2.4	5.2
Waist Hip Ratio (WHR)	3.8	16.9	61.3	-4.1	-4.5	1.2	-3.3	-4.2	-7.8	-4.4	-4.5	-1.6	-4.6	4.9	-3.8	-4.3	-4.4	-1.0	-0.4	-4.2
Deep venous thrombosis (DVT) (self-reported)	3.7	4.8	7.8	2.5	2.6	0.5	2.0	1.5	1.9	2.7	2.7	2.4	2.1	0.0	2.8	2.7	2.3	1.1	2.3	2.6
Mean Putamen Volume	3.6	4.1	6.8	-2.4	-2.4	1.8	-1.3	-2.0	-1.3	-2.4	-2.6	-2.0	-2.5	-1.2	-1.9	-2.2	-1.9	-1.2	-2.4	-2.1
Townsend deprivation index at recruitment	3.4	4.8	10.4	2.4	2.2	0.8	2.1	2.4	-0.5	2.5	2.0	3.2	2.6	0.1	2.5	2.4	2.4	2.2	2.4	2.1
Hayfever/allergic rhinitis (self-reported)	3.2	4.2	8.8	2.1	2.1	1.4	2.5	1.9	0.9	2.0	2.0	3.0	1.9	-1.1	2.0	2.2	2.3	2.2	1.4	2.5
Medication: Ibuprofen	3.2	3.9	9.1	1.9	2.2	-1.3	3.0	2.7	1.9	1.9	2.2	2.8	2.3	0.1	1.4	2.0	1.6	0.2	1.3	1.9
Lung FVC	3.1	15.8	26.1	-4.8	-4.8	2.5	-5.1	-4.9	-3.2	-4.8	-4.5	-4.2	-5.0	1.5	-4.0	-4.4	-3.1	-0.1	-1.8	-4.6
Crohns Disease (2012)	3.0	4.8	7.3	2.6	2.5	-0.0	2.4	2.1	1.1	2.5	2.6	2.5	2.1	0.1	2.4	2.5	2.6	2.0	2.1	2.7
Medication: Metformin	2.9	4.1	6.1	-2.1	-2.0	-0.5	-2.4	-2.4	-1.7	-2.2	-2.4	-1.7	-2.4	2.3	-2.1	-2.1	-2.5	-1.4	-0.2	-2.2
Medication: Ibuprofen (e.g. Nurofen)	2.9	3.7	8.9	2.1	2.2	-0.8	3.0	2.5	2.0	2.0	2.1	2.8	2.0	-0.1	1.4	2.0	1.6	0.1	1.5	1.8
Glaucoma (self-reported)	2.9	3.4	8.4	1.9	2.0	-0.6	2.9	2.6	0.8	2.0	2.1	2.8	2.1	-0.2	1.7	2.1	1.6	0.3	0.9	1.8
Type 2 Diabetes (T2D) (2018)	2.7	5.1	10.8	-2.1	-2.0	-0.4	-3.3	-2.8	-2.7	-2.2	-2.6	-2.5	-2.8	2.4	-2.1	-2.1	-2.3	-0.9	-0.5	-2.1
Height	2.6	49.2	78.9	8.2	8.3	-7.8	8.9	8.5	6.9	8.0	7.5	8.3	7.9	1.3	6.2	7.7	5.4	1.4	1.7	7.5
Weight	2.6	13.0	19.2	4.3	4.3	-2.6	3.8	4.0	4.1	4.4	4.0	3.5	3.9	0.6	4.2	4.2	3.3	0.2	2.0	4.0
Commuting to job workplace: Public transport	2.6	3.1	6.1	1.6	1.7	1.3	2.5	1.7	1.2	1.5	1.7	2.4	1.9	-2.0	1.8	1.9	2.2	1.1	0.6	1.8
Heart disease (siblings)	2.6	3.2	7.1	-1.8	-1.4	-1.0	-2.5	-2.7	-2.4	-1.8	-1.6	-2.6	-1.7	0.6	-1.3	-1.7	-2.2	-1.4	-0.5	-1.4
Impedance of whole body	2.6	13.1	20.9	-4.6	-4.4	-0.8	-3.6	-3.3	-3.5	-4.6	-3.7	-3.8	-3.8	1.1	-4.5	-4.5	-3.9	-1.0	-2.8	-4.2
Serious illness, injury or assault to yourself	2.5	3.0	5.7	-2.1	-1.7	-0.5	-0.7	-1.6	-0.9	-2.1	-1.8	-1.6	-1.8	-1.0	-1.8	-1.9	-2.3	-2.4	-2.0	-1.9
Diabetes (self-reported)	2.5	3.9	10.7	-1.3	-1.1	-1.1	-3.3	-2.9	-2.5	-1.4	-2.0	-2.0	-2.6	3.2	-1.3	-1.2	-1.8	-1.0	1.0	-1.3
Family relationship satisfaction	2.5	3.1	6.2	1.7	1.8	1.1	0.7	1.5	-0.2	1.9	2.0	1.3	2.5	-0.8	2.5	2.0	2.2	2.2	1.9	1.9
Diabetes diagnosed by doctor	2.5	4.1	10.7	-1.6	-1.4	-0.8	-3.3	-3.0	-2.7	-1.6	-2.3	-2.1	-2.6	2.6	-1.4	-1.5	-2.0	-1.0	0.5	-1.6
Primary Biliary Cirrhosis	2.4	3.4	6.3	-2.3	-2.3	0.8	-1.2	-1.1	-0.1	-2.2	-2.3	-1.8	-2.1	-1.2	-2.5	-2.2	-1.8	-1.1	-2.2	-2.3
Serious illness, injury or assault of a close relative in last 2 years	2.4	2.7	6.5	1.6	1.6	1.6	2.1	1.4	0.7	1.7	1.8	2.5	1.4	0.0	1.2	1.7	1.9	1.8	1.8	1.7
Impedance of arm (right)	2.3	10.5	17.6	-4.2	-4.1	-0.5	-3.0	-2.9	-2.8	-4.2	-3.5	-3.3	-3.4	0.5	-4.0	-4.1	-3.4	-0.5	-3.0	-3.7
Ever highly irritable/argumentative for 2 days	2.2	2.6	7.4	-1.6	-1.5	-1.9	0.2	-1.4	-0.6	-1.7	-1.5	-0.8	-1.4	-0.1	-2.0	-1.7	-2.3	-2.7	-1.7	-1.8
Alcohol drinker status: Never	2.2	2.6	4.9	-2.2	-1.8	-0.2	-1.6	-1.0	-0.7	-2.1	-1.7	-2.0	-1.4	0.7	-1.9	-1.9	-1.8	-1.3	-1.1	-2.2
Standing height	2.1	21.0	39.4	4.9	5.0	-5.2	6.3	5.9	5.5	4.8	5.1	5.4	5.5	0.6	3.6	4.6	3.4	0.6	0.7	4.6
Medication: Atorvastatin	2.1	2.6	6.7	-1.9	-1.6	-0.6	-1.9	-2.1	-0.0	-1.9	-1.8	-2.6	-2.4	-0.1	-1.1	-1.6	-1.2	-0.3	-1.5	-1.6
Multivitamins +/- minerals	2.0	2.6	5.3	1.7	1.9	-0.8	1.5	1.2	0.3	1.7	1.8	2.3	1.8	1.5	1.9	1.8	1.2	0.9	2.2	1.6
Allergy or Eczema	1.9	4.9	18.9	-2.4	-2.5	4.3	-0.3	-2.6	-0.4	-2.6	-2.0	-0.6	-2.2	-3.2	-2.0	-2.3	-1.7	-1.2	-1.3	-1.7
Pulse rate	1.9	3.2	7.1	-2.0	-2.2	0.2	-2.0	-1.7	-2.7	-2.0	-2.0	-1.8	-1.8	0.4	-1.8	-2.0	-1.6	-1.5	-0.7	-2.1
Commuting to job workplace: Car/motor vehicle	1.9	2.2	8.0	-0.9	-1.2	-1.6	-2.8	-1.9	-0.6	-1.0	-1.6	-2.6	-1.8	0.6	-1.2	-1.2	-1.2	-0.8	-0.5	-1.1
Average weekly beer plus cider intake	1.9	2.8	6.8	1.9	1.9	0.4	1.1	1.2	-0.5	1.9	1.4	2.4	1.6	1.6	1.6	2.0	1.8	1.5	2.6	1.6
Triglycerides	1.8	3.0	4.5	-2.1	-1.9	1.3	-2.1	-1.7	-1.7	-2.1	-1.9	-2.1	-1.7	0.6	-1.8	-2.0	-1.9	-1.1	-0.8	-1.9
Sitting height	1.8	12.8	21.2	4.1	4.1	-3.6	4.6	4.5	4.1	3.9	3.9	4.0	3.9	0.6	3.0	3.8	3.1	1.1	1.2	3.9
Ever had prostate specific antigen (PSA) test	1.8	2.1	4.9	-1.5	-1.5	0.2	-0.8	-1.0	-0.0	-1.5	-1.7	-1.3	-1.6	-0.1	-1.7	-1.6	-1.8	-2.2	-1.9	-1.7
Alzheimer’s Disease (including proxy)	1.7	2.5	7.5	1.1	1.4	-1.6	2.7	2.2	1.7	1.2	2.1	1.9	1.8	-1.0	1.2	1.3	0.9	-0.1	-0.1	1.7
Age at First Birth	1.7	2.5	6.1	1.6	1.9	-0.7	1.8	1.0	0.4	1.6	1.5	2.5	1.4	1.6	2.0	1.8	1.2	1.2	2.2	1.4
Hip circumference	1.7	7.4	18.3	3.2	3.3	-2.6	2.6	2.9	4.3	3.3	2.9	1.8	2.6	-0.2	3.1	3.2	2.3	-0.3	0.9	2.8
Impedance of arm (left)	1.7	7.9	12.4	-3.5	-3.5	-0.7	-2.9	-2.6	-2.5	-3.5	-2.9	-3.0	-2.9	0.3	-3.4	-3.5	-2.8	0.1	-2.8	-3.1
Shortness of breath walking on level ground	1.7	2.1	3.9	1.6	1.3	1.1	1.3	0.9	0.3	1.6	1.5	1.6	1.5	-0.7	1.9	1.6	1.8	2.0	1.0	1.6
Ever had bowel cancer screening	1.7	2.0	4.0	1.4	1.8	-1.7	0.2	0.9	-0.2	1.4	1.4	0.8	1.7	0.6	1.8	1.8	1.3	1.1	1.9	2.0
Diabetes (mother)	1.6	2.1	6.6	-1.5	-1.3	0.3	-2.6	-1.3	-2.1	-1.6	-1.9	-1.5	-1.4	1.5	-1.2	-1.3	-1.1	0.3	0.1	-1.3
Mouth/teeth dental problems: Dentures	1.6	2.7	5.6	-1.6	-1.9	0.9	-1.5	-2.4	-1.0	-1.7	-2.0	-1.8	-2.2	-1.2	-1.3	-1.8	-1.4	0.2	-2.2	-1.6
Back pain experienced in last month	1.6	2.3	4.4	1.9	2.1	0.5	1.4	1.9	0.8	1.9	1.5	1.6	1.8	-0.8	1.4	2.0	1.6	0.2	0.8	2.0
Osteoarthritis (self-reported)	1.6	2.0	5.9	1.2	1.4	-0.5	0.2	1.3	1.0	1.4	1.7	1.0	1.2	1.8	1.4	1.6	1.9	1.4	2.4	1.2
Wears glasses or contact lenses	1.6	1.8	5.7	1.6	1.7	-2.4	0.1	0.1	0.9	1.5	1.5	-0.0	0.9	0.4	1.4	1.6	1.3	2.0	0.2	1.9
Eye problems/disorders: Glaucoma	1.6	1.9	5.7	1.5	1.5	-0.3	2.2	2.4	0.7	1.5	1.5	1.7	1.5	-0.4	0.8	1.5	1.4	0.3	0.2	1.3
Alzheimer’s Disease (in father)	1.5	1.6	4.5	1.1	1.2	-0.9	1.9	2.1	1.2	1.1	1.7	1.6	1.4	-0.2	1.0	1.2	1.1	0.7	0.3	1.3
Average weekly red wine intake	1.5	2.3	3.5	1.6	1.6	-1.5	1.0	0.3	-0.6	1.6	1.7	1.9	1.2	1.8	1.6	1.6	1.3	1.9	1.8	1.6
Happiness	1.4	1.7	3.8	1.5	1.4	-0.2	0.1	0.0	-1.4	1.5	1.5	0.9	1.3	0.8	2.0	1.5	1.6	1.6	1.4	1.4
Emphysema/chronic bronchitis	1.4	1.5	5.8	0.7	0.9	-1.1	2.4	1.2	1.8	0.9	1.3	1.9	1.7	-0.8	0.8	0.8	0.1	-1.1	-0.4	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.6	2.6	-1.6	-1.5	0.6	-1.1	-0.8	-1.1	-1.6	-1.5	-1.4	-1.2	-0.4	-1.6	-1.4	-1.5	-1.2	-1.2	-1.4
Medication: Gliclazide	1.4	1.6	8.9	-0.6	-0.9	0.4	-1.8	-2.3	-3.0	-0.7	-1.4	-1.0	-1.3	0.9	-0.8	-0.9	-0.8	-0.2	0.5	-0.8
Supplements: Calcium	1.4	1.6	4.4	-1.5	-1.3	-0.1	0.1	-1.4	0.1	-1.4	-1.3	-0.4	-1.1	-0.7	-1.4	-1.4	-1.9	-2.1	-1.4	-1.3
Crohns Disease (2017)	1.3	2.8	4.6	1.8	1.8	0.1	2.1	1.7	-0.0	1.8	2.0	2.1	1.6	-0.3	2.0	1.9	1.9	1.2	1.2	2.1
Heart attack	1.3	1.7	4.0	-1.2	-1.3	-0.1	-1.8	-1.5	-0.2	-1.3	-1.9	-1.4	-2.0	0.6	-0.9	-1.2	-1.4	-1.4	-0.3	-1.4
Time employed in main current job	1.3	1.4	3.9	1.3	1.2	-0.3	0.8	1.6	-0.3	1.2	1.3	1.0	1.3	-0.0	1.3	1.3	1.5	2.0	0.3	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.0	4.2	-1.4	-1.4	1.3	-0.6	-1.2	-0.8	-1.4	-1.6	-1.2	-1.3	-1.6	-1.6	-1.6	-1.6	-2.0	-1.3	-1.5
Medication: Omeprazole	1.3	1.6	5.0	-1.7	-1.2	0.5	0.6	-0.1	1.0	-1.6	-1.2	-0.4	-1.0	-1.4	-1.1	-1.2	-1.6	-2.2	-1.4	-1.2
Chronotype (morning person)	1.2	2.9	7.7	-1.7	-1.8	0.0	-2.8	-1.5	-1.4	-1.8	-1.8	-2.8	-1.9	0.7	-1.6	-1.8	-1.6	-0.2	-0.8	-1.8
Ever used hormone-replacement therapy (HRT)	1.2	1.5	3.2	1.3	1.5	-0.7	0.9	0.6	0.5	1.2	1.6	0.6	0.9	-0.5	1.6	1.5	1.6	1.6	0.9	1.8
Supplements: Zinc	1.2	1.3	2.7	-1.2	-1.2	0.7	-1.2	-1.6	0.2	-1.2	-1.3	-0.9	-1.4	0.1	-1.0	-1.2	-1.5	-1.5	-0.0	-1.4
Number of children fathered	1.2	1.3	3.0	-0.9	-1.1	-1.7	-0.9	-1.2	-0.4	-1.0	-0.8	-1.7	-1.2	0.9	-1.1	-1.1	-1.2	-1.5	-1.2	-1.0
Medication for cholesterol	1.2	1.8	7.8	-1.0	-1.2	1.3	-0.8	-0.7	0.7	-1.0	-1.3	-1.5	-0.4	-2.8	-1.4	-1.3	-0.9	-1.3	-1.9	-1.3
Alcohol intake versus 10 years previously	1.1	1.7	3.1	1.5	1.6	-0.7	1.7	1.8	1.2	1.5	1.4	1.4	1.5	-0.5	1.2	1.4	0.9	-0.2	0.7	1.4
Arm fat mass (right)	1.1	4.7	8.3	2.6	2.6	-2.0	1.9	2.3	2.4	2.7	2.3	1.7	2.1	1.0	2.9	2.6	1.9	-0.1	1.6	2.4
Chronic bronchitis/emphysema (mother)	1.1	1.3	2.9	1.3	1.0	0.6	1.7	1.2	-0.2	1.3	1.3	1.6	1.4	-0.7	1.5	1.1	1.0	0.3	0.7	1.1
Arm fat mass (left)	1.1	4.4	7.8	2.5	2.5	-2.0	2.0	2.3	2.4	2.6	2.2	1.7	2.0	0.8	2.8	2.5	1.8	-0.1	1.3	2.3
Hearing aid user	1.1	1.2	6.8	-0.8	-0.9	1.8	-0.1	-0.3	0.3	-0.9	-1.1	-0.9	-0.9	-2.6	-1.1	-0.8	-0.5	-0.7	-1.5	-0.7
Medication: Bendroflumethiazide	1.1	1.6	3.4	1.1	1.3	0.2	0.5	1.5	-0.1	1.1	1.9	1.0	1.5	1.2	1.4	1.3	1.4	1.4	1.8	1.4
Heart attack/myocardial infarction (self-reported)	1.1	1.5	3.6	-1.1	-1.2	-0.2	-1.7	-1.4	-0.1	-1.2	-1.8	-1.4	-1.9	0.5	-0.8	-1.1	-1.3	-1.3	-0.4	-1.3
Bipolar Disorder (2018)	1.0	1.6	3.0	1.4	1.4	-1.1	1.2	0.3	1.1	1.4	1.5	1.3	0.6	0.9	1.7	1.5	1.3	0.8	1.5	1.5
HDL Cholesterol	1.0	1.7	4.5	1.4	1.4	-1.2	0.5	1.3	1.0	1.3	1.4	0.7	0.9	0.3	1.4	1.6	2.1	2.1	0.6	1.5
Hayfever, allergic rhinitis or eczema	1.0	2.1	11.4	-1.4	-1.4	3.4	0.0	-1.8	-0.2	-1.7	-1.2	0.1	-1.3	-2.4	-1.1	-1.3	-0.9	-0.7	-0.6	-0.8
Medication: Blood pressure	1.0	1.8	4.0	-1.4	-1.2	-0.9	-1.8	-1.0	0.1	-1.4	-1.7	-2.0	-1.5	0.7	-1.2	-1.3	-1.6	-1.4	-0.9	-1.4
Comparative height size at age 10	1.0	5.5	9.5	2.8	2.6	-2.9	2.9	2.6	3.1	2.6	2.6	2.4	2.8	0.4	2.2	2.4	1.6	-0.1	0.3	2.3
Type 2 Diabetes (T2D) (2012)	0.9	1.0	4.5	-1.3	-1.0	2.1	-1.8	-0.3	-1.0	-1.1	-0.5	-0.4	-0.2	0.7	-0.2	-0.7	0.0	0.9	1.1	-0.8
Average weekly spirits intake	0.9	1.1	2.1	1.0	1.1	0.3	0.2	0.9	-1.1	1.1	1.1	0.5	1.4	0.3	1.5	1.1	1.1	1.5	1.2	1.1
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	3.1	-1.1	-0.8	0.0	-1.5	-1.8	-1.6	-1.0	-1.1	-1.1	-1.0	0.6	-0.5	-0.7	-0.9	-0.4	0.2	-0.7
Qualifications: CSEs or equivalent	0.9	1.2	3.8	0.8	1.0	0.1	1.7	1.9	1.1	1.0	1.4	1.3	1.5	-0.2	0.5	1.0	1.0	0.2	0.8	1.0
Hearing difficulty/problems with background noise	0.9	1.4	3.0	-1.2	-1.0	0.7	-1.3	-1.7	-1.0	-1.1	-1.3	-1.4	-1.3	-1.2	-1.4	-1.1	-1.0	-0.9	-1.0	-1.0
Hair/balding pattern: Pattern 3	0.9	1.3	3.0	-1.4	-1.4	-0.7	-0.9	-1.1	0.1	-1.3	-1.3	-0.6	-1.6	0.8	-1.7	-1.4	-0.9	-0.7	-0.6	-1.6
Medication: Cholesterol lowering	0.9	1.3	3.2	-1.1	-1.1	-1.0	-1.8	-1.1	0.2	-1.2	-1.4	-1.6	-1.3	1.2	-0.7	-1.2	-1.3	-0.3	-0.8	-1.3
Prospective memory result	0.9	1.1	3.3	-1.4	-1.0	-0.7	-0.3	-1.1	-0.2	-1.2	-1.0	-0.8	-0.8	-0.1	-0.9	-1.2	-1.7	-1.8	-1.1	-1.2
Had major operations	0.9	1.1	4.3	-0.9	-0.6	0.4	0.2	-0.6	1.6	-0.9	-1.1	-0.6	-1.2	-2.1	-0.6	-0.7	-0.8	-1.2	-1.5	-0.7
Number of self-reported non-cancer illnesses	0.9	1.5	5.2	-1.4	-1.1	0.5	-1.7	-2.3	-1.4	-1.5	-1.2	-0.9	-1.2	0.8	-0.6	-1.2	-1.4	-0.7	0.5	-0.9
Age started oral contraceptive pill	0.9	1.1	3.4	1.0	1.0	-0.7	-0.4	0.3	0.1	0.8	1.0	0.6	0.5	1.8	1.1	1.1	1.3	1.4	1.8	1.0
Alzheimer’s Disease (in mother)	0.8	1.0	3.7	0.3	0.7	-1.4	1.9	1.3	1.5	0.5	1.1	1.0	1.2	-0.7	0.5	0.6	0.2	-0.5	-0.6	0.9
Blood Eosinophil Count	0.8	6.0	22.4	2.1	1.4	4.7	1.9	0.9	0.4	2.0	1.6	1.9	1.5	-4.4	2.2	1.8	3.3	3.4	0.8	2.3
Frequency of depressed mood in last 2 weeks	0.8	1.1	3.0	-1.0	-1.0	1.0	-1.0	-1.7	-1.2	-1.0	-1.1	-0.6	-1.4	0.6	-0.9	-1.1	-1.1	-0.6	-0.6	-1.4
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	2.4	-1.2	-1.3	1.1	-0.9	-1.0	-0.4	-1.2	-0.9	-1.5	-1.1	-1.5	-0.5	-1.0	-0.4	0.1	-0.9	-0.9
Trunk fat mass	0.8	3.5	8.9	2.1	2.1	-3.0	1.6	1.8	1.9	2.2	1.9	1.3	1.7	1.4	2.5	2.1	1.2	-0.3	1.1	1.9
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	2.5	1.2	1.2	0.7	1.3	0.8	-0.2	1.2	1.6	1.6	1.5	-0.5	1.1	1.3	1.5	1.2	1.1	1.4
High blood pressure (siblings)	0.8	1.1	2.7	-1.3	-1.0	0.2	-0.9	-1.6	0.3	-1.3	-1.3	-1.2	-1.6	-0.2	-0.8	-1.0	-1.2	-1.1	-0.0	-1.0
Wheeze or whistling in the chest in last year	0.8	1.4	5.4	0.9	0.7	2.0	1.4	0.4	1.4	0.9	0.9	1.2	0.8	-2.3	1.1	1.0	1.3	0.5	0.3	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	4.3	-0.7	-0.7	0.0	-0.9	-1.8	-2.1	-0.7	-0.9	-1.2	-1.1	-0.1	-0.6	-0.8	-0.8	0.2	-0.4	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	5.6	1.2	1.4	-0.7	1.4	1.3	2.4	1.3	1.3	1.4	1.1	-0.1	0.9	1.4	1.5	0.9	0.3	1.3
Commuting to job workplace: Cycle	0.8	1.0	5.2	0.2	0.2	0.5	2.3	0.8	1.5	0.2	0.6	0.9	0.6	-1.8	-0.0	0.1	-0.1	-1.2	-1.1	0.1
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	2.7	-1.4	-1.0	1.0	0.2	-0.2	0.8	-1.3	-0.8	-0.4	-0.7	-1.4	-0.6	-0.9	-1.2	-1.6	-1.1	-0.8
Bipolar Disorder (2011)	0.7	0.7	3.6	0.4	0.3	-1.5	-0.2	0.0	-1.2	0.3	0.4	0.3	0.2	1.9	0.5	0.5	0.3	1.3	1.3	0.6
LDL Cholesterol	0.7	1.1	3.1	1.2	1.2	0.7	0.7	-0.1	0.8	1.2	1.5	0.9	1.0	-0.3	1.7	1.3	0.9	0.6	1.5	1.0
Respiratory disease	0.7	1.5	11.3	-0.3	-0.6	2.0	1.4	-1.1	0.7	-0.3	-0.3	0.3	-0.4	-3.4	-0.4	-0.5	-0.4	-1.0	-1.8	-0.2
Severe depression (siblings)	0.7	0.8	3.6	-1.0	-1.0	1.9	-0.6	-0.8	0.5	-0.9	-1.1	-0.6	-1.1	-0.8	-0.6	-0.8	-0.3	-0.5	-0.2	-0.9
Age when periods started (menarche)	0.7	1.7	9.4	-0.7	-1.0	3.1	1.1	0.8	1.3	-0.7	-0.4	0.1	-0.4	-3.0	-0.8	-0.6	0.5	0.6	-1.6	-0.6
Body mass index (BMI)	0.7	3.0	7.3	2.2	2.2	-0.4	1.1	1.4	1.7	2.3	1.7	1.1	1.4	0.4	2.7	2.3	1.8	-0.1	1.8	2.0
Number of incorrect matches in round	0.7	1.2	1.9	-1.4	-1.3	-0.8	-1.1	-1.1	0.2	-1.3	-1.3	-1.4	-1.0	0.3	-0.9	-1.3	-1.3	-0.3	-1.3	-1.1
Illnesses of siblings	0.7	1.0	2.9	1.1	0.8	0.2	0.5	1.6	0.3	1.1	1.1	1.1	1.1	0.7	0.9	1.0	1.4	1.7	0.2	1.0
Falls in the last year	0.7	1.0	3.3	-1.2	-1.0	1.1	-1.8	-1.2	-0.5	-1.1	-1.0	-1.6	-1.0	-0.4	-0.2	-0.9	-0.6	-0.3	0.6	-1.0
Number of live births	0.7	1.0	3.8	-0.3	-0.3	-1.2	-1.6	-1.3	-1.6	-0.3	-0.4	-1.2	-0.8	2.0	-0.2	-0.2	-0.3	1.2	0.7	-0.0
Asthma	0.7	1.4	6.8	-0.9	-0.9	1.2	-0.8	-2.6	-0.6	-0.9	-1.0	-1.1	-1.2	-1.7	-0.5	-0.9	-1.1	-1.1	-1.2	-0.5
Depression (self-reported)	0.7	0.8	1.7	-1.1	-0.8	-1.3	-0.4	-1.0	0.2	-1.0	-0.8	-0.6	-0.8	0.2	-0.9	-1.0	-1.3	-0.9	-1.0	-0.9
Loud music exposure frequency	0.7	0.8	1.9	1.0	1.2	-0.7	0.7	0.5	-0.3	1.0	0.7	0.9	0.9	-0.9	1.2	1.0	0.7	0.7	0.3	1.4
Whole body fat mass	0.7	3.0	7.4	1.9	2.0	-2.7	1.3	1.6	1.7	2.0	1.7	1.1	1.5	1.5	2.4	1.9	1.1	-0.6	1.1	1.7
Illnesses of father: Heart disease	0.7	1.0	3.7	-1.1	-0.8	0.1	-1.0	-0.7	0.6	-1.1	-1.3	-1.3	-1.9	0.2	-1.0	-0.9	-1.0	-0.5	-1.0	-0.8
Smoking status: Previous	0.7	1.0	2.7	-1.0	-1.1	1.2	-0.2	-1.4	0.4	-1.0	-1.1	-0.6	-1.1	-0.6	-0.9	-1.1	-1.3	-1.6	-0.6	-1.1
Friendships satisfaction	0.7	0.9	2.4	0.8	1.2	-0.8	-0.0	0.5	-0.3	0.9	1.1	0.6	1.2	1.0	1.6	1.1	0.7	0.7	1.3	0.8
Osteoporosis (self-reported)	0.7	0.9	1.6	-1.2	-1.1	0.4	-0.6	-0.8	-0.2	-1.1	-1.0	-0.8	-0.7	-1.1	-1.3	-1.1	-0.9	-1.1	-0.8	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	4.4	-1.1	-1.2	1.6	-2.1	-0.4	-2.1	-1.2	-1.2	-1.0	-0.6	1.1	-0.9	-1.0	0.0	1.6	0.1	-0.9
Miserableness	0.7	1.2	2.3	1.3	1.5	-0.1	0.7	0.1	-0.6	1.3	1.1	1.5	1.0	1.3	1.3	1.3	0.8	0.4	1.4	1.2
Cholesterol lowering medication	0.7	1.1	6.5	0.6	0.7	-1.1	0.4	0.4	-0.8	0.6	0.8	0.9	0.3	2.5	0.7	0.8	0.7	0.9	2.0	0.9
Depressed Affect (Nagel 2018)	0.6	1.2	2.3	1.3	1.5	-0.8	0.3	0.5	-0.4	1.3	1.4	1.0	1.3	1.2	1.5	1.2	0.8	0.7	1.1	0.9
Major Depression (MDD)	0.6	0.8	1.6	1.0	0.9	-0.0	0.5	0.7	-0.1	1.0	1.1	0.6	1.2	0.6	1.2	1.0	1.0	0.9	0.6	1.2
Angina	0.6	0.8	2.6	-0.8	-0.6	-1.3	-1.6	-0.8	-0.1	-0.8	-1.0	-1.4	-0.9	1.2	-0.5	-0.7	-0.9	-0.3	-0.3	-0.6
Maternal smoking around birth	0.6	0.8	4.4	0.3	0.2	2.1	-1.5	0.3	-0.3	0.3	0.2	-0.5	0.5	0.4	0.7	0.5	1.1	1.0	1.8	0.3
High blood pressure (mother)	0.6	0.9	3.1	0.1	-0.0	1.7	-1.5	-0.5	-1.3	0.0	-0.4	-0.3	-0.2	1.1	0.1	0.1	0.6	1.8	1.6	0.1
Nervous feelings	0.6	1.2	2.6	-1.4	-1.3	0.8	-0.1	-1.1	0.1	-1.3	-1.0	0.2	-0.7	0.5	-1.3	-1.4	-1.6	-1.2	-0.5	-1.6
Medication: Ventolin 100micrograms inhaler	0.6	0.8	4.8	-0.5	-0.5	2.2	0.2	-1.6	-0.1	-0.4	-0.7	0.3	-1.2	-1.1	-0.8	-0.5	-0.5	-0.6	-0.5	-0.3
Exposure to tobacco smoke outside home	0.6	0.8	6.9	-0.0	-0.3	2.6	-1.2	-1.2	-1.2	-0.1	-0.4	-0.6	-0.8	0.0	-0.0	-0.2	0.2	0.2	0.6	-0.1
Medication: Allopurinol	0.6	0.7	1.5	-0.8	-1.1	-0.1	-0.9	-0.8	-0.5	-0.9	-0.9	-0.8	-0.4	-0.6	-0.6	-1.2	-1.2	-0.6	-1.0	-1.2
Pulse rate, automated reading	0.6	1.9	4.9	-1.2	-1.4	-0.8	-0.8	-0.8	-2.2	-1.3	-1.7	-1.0	-1.6	0.5	-1.6	-1.5	-1.5	-1.1	-1.5	-1.5
Commuting to job workplace: Walk	0.6	0.6	2.9	0.4	0.7	0.5	1.7	0.3	0.7	0.5	0.5	1.1	0.3	-1.0	0.9	0.7	0.4	0.6	-0.6	1.1
Breast cancer (self-reported)	0.6	0.7	1.8	0.7	0.8	-1.4	0.6	0.6	1.2	0.8	1.1	0.4	0.8	0.1	1.1	0.9	0.8	1.0	0.8	0.9
Asthma (self-reported)	0.6	1.2	6.2	-0.8	-0.8	1.3	-0.6	-2.5	-0.5	-0.8	-1.0	-0.9	-1.2	-1.8	-0.5	-0.8	-1.0	-0.9	-1.2	-0.4
Medication: Aspirin	0.6	0.8	3.0	-1.0	-0.8	-0.2	-1.7	-1.0	0.2	-0.9	-1.0	-1.4	-0.7	1.1	-0.7	-0.8	-0.8	-0.3	0.4	-0.6
Ever taken oral contraceptive pill	0.6	0.6	3.8	-0.1	-0.1	-0.4	0.8	1.9	1.3	-0.1	-0.1	0.5	0.3	-0.5	-1.3	-0.3	0.1	-0.1	-1.5	-0.3
Medication: Blood pressure	0.6	1.2	5.9	0.6	0.9	-1.4	0.6	0.7	-0.5	0.6	1.2	1.0	0.6	2.4	1.0	0.9	0.5	0.9	1.9	0.9
Ever smoked	0.6	1.1	2.3	-0.8	-1.2	0.7	0.1	-1.0	-0.2	-0.8	-1.4	-0.4	-1.4	-0.5	-1.4	-1.2	-1.3	-1.5	-1.4	-1.1
Pack years of smoking	0.6	0.9	3.0	0.9	1.0	-0.9	1.7	1.0	1.5	0.9	0.8	1.2	0.4	-0.4	1.0	1.0	0.8	-0.0	0.1	0.8
Ulcerative Colitis (UC)	0.5	0.9	2.0	-1.3	-1.2	-0.0	-0.2	0.6	0.8	-1.2	-0.4	-1.3	0.2	-1.4	-0.7	-1.2	-0.7	-0.9	-1.4	-0.7
Breast Cancer	0.5	1.2	3.2	-0.9	-0.9	-0.8	-1.4	-1.4	-1.8	-1.3	-0.9	-1.5	-1.1	0.2	-0.7	-1.1	-1.4	-0.5	-0.8	-0.8
Rheumatoid Arthritis	0.5	0.6	3.0	-0.3	-0.4	1.6	-1.7	-0.2	-1.4	-0.1	-0.3	-1.5	-0.0	-0.6	-0.2	-0.4	0.2	0.4	-0.0	-0.2
Heel T-Score	0.5	3.7	8.8	-1.5	-1.7	1.1	-2.6	-2.8	-2.9	-1.9	-1.9	-1.0	-2.3	3.0	-1.2	-1.7	-1.5	0.8	0.9	-1.8
Diabetes (father)	0.5	0.6	3.2	-0.2	-0.3	-0.8	-1.8	-1.0	-0.1	-0.2	-0.8	-1.4	-0.9	1.4	-0.2	-0.3	-0.2	0.1	0.0	-0.4
Pack years adult smoking proportion	0.5	0.8	2.5	0.9	1.0	-0.9	1.6	1.0	1.3	0.9	0.7	1.2	0.3	-0.3	0.9	1.0	0.8	0.0	0.1	0.8
Supplements: Glucosamine	0.5	0.7	4.4	0.4	0.8	-1.8	0.4	0.1	1.2	0.3	0.3	0.7	0.2	2.1	0.8	0.6	-0.2	-0.2	-0.3	0.3
Chronic bronchitis/emphysema (father)	0.5	0.6	1.8	0.9	0.6	1.1	0.9	0.4	1.0	0.9	0.5	0.9	0.5	-1.3	0.5	0.7	0.7	0.1	0.3	0.3
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.7	0.5	0.5	-1.5	1.0	-0.0	1.3	0.6	0.4	0.4	0.3	-0.6	0.3	0.4	-0.2	-1.7	-0.4	0.3
Medication: Simvastatin	0.5	0.7	5.7	0.5	0.5	-1.6	-0.4	0.8	-0.3	0.5	0.5	0.3	0.7	2.4	0.4	0.4	0.1	0.4	1.0	0.5
Noisy workplace	0.5	0.6	1.5	-0.6	-0.9	0.2	-0.6	-0.6	-0.2	-0.7	-0.9	-0.5	-1.1	-0.6	-1.2	-0.9	-0.7	-0.8	-0.9	-1.0
Illnesses of mother	0.5	0.6	4.2	0.2	0.5	-2.1	0.8	-0.4	0.9	0.3	0.4	-0.1	0.0	-1.1	0.2	0.3	-0.2	-0.7	-1.4	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.1	-0.9	-1.0	-0.2	-1.1	-0.7	0.3	-0.8	-0.8	-1.0	-0.7	0.8	-0.8	-0.9	-0.4	0.8	-0.3	-0.7
Qualifications: College or University degree	0.5	1.4	5.9	-1.4	-1.1	0.9	-1.8	-2.4	-0.9	-1.4	-0.9	-1.4	-1.5	-0.1	-0.7	-1.1	-0.7	-0.1	-0.6	-0.7
Migraine (self-reported)	0.5	0.7	2.4	-0.9	-0.6	1.4	0.6	0.1	1.5	-1.0	-0.4	0.4	-0.3	-0.6	-0.6	-0.5	-0.3	-1.5	-0.4	-0.9
Knee pain experienced in last month	0.5	0.8	6.0	0.2	-0.0	2.4	0.4	0.8	1.6	0.2	0.6	0.6	0.6	-1.4	-0.1	0.1	0.7	0.4	-0.2	0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	1.7	0.6	0.9	0.2	0.5	0.1	1.3	0.7	0.7	0.6	0.4	-0.6	1.1	0.9	0.8	0.1	1.1	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	1.5	0.9	0.7	-0.8	0.7	1.2	0.5	0.9	0.7	0.6	0.5	0.8	0.3	0.7	0.7	0.9	0.6	0.8
Ever depressed for a whole week	0.5	0.7	2.5	-0.8	-0.7	-1.1	-0.6	-0.2	0.8	-0.7	-0.8	-0.7	-0.4	-0.1	-0.8	-0.8	-1.2	-1.6	-0.5	-0.9
Unable to work because of sickness or disability	0.5	0.7	2.7	-0.7	-1.0	0.4	-0.4	-0.2	0.4	-0.7	-1.0	-1.0	-0.9	-1.6	-0.7	-0.8	-0.5	-0.8	-1.0	-1.0
Leg fat mass (left)	0.5	1.8	4.6	1.5	1.5	-2.1	0.8	1.2	1.5	1.6	1.2	0.5	1.0	1.5	1.9	1.5	0.8	-1.0	1.1	1.2
Bipolar Disorder or Schizophrenia	0.4	0.9	4.2	0.8	0.8	-1.3	1.4	0.3	2.0	0.8	1.0	1.4	0.6	0.1	0.8	0.8	0.6	0.1	0.8	0.6
Reaction Time	0.4	0.8	3.2	0.9	0.5	1.3	0.3	0.1	-1.4	0.8	0.5	0.9	0.4	-1.0	0.3	0.6	1.1	1.8	0.3	0.7
HbA1C	0.4	0.5	3.6	-0.3	-0.3	1.9	-1.0	-0.5	-0.6	-0.3	-0.4	-0.7	-0.5	0.2	-0.5	-0.1	0.3	0.2	0.9	-0.2
Schizophrenia (2014)	0.4	0.9	4.4	0.1	0.0	0.4	1.9	0.2	1.9	0.2	0.3	1.4	0.3	-2.1	-0.1	0.1	0.1	-0.8	-0.5	-0.1
BMI	0.4	2.5	5.4	1.9	1.8	-1.1	1.4	1.5	1.8	2.2	1.8	0.8	1.7	0.2	2.3	1.9	1.2	-0.9	1.0	1.6
Lung FEV1/FVC ratio	0.4	2.1	10.3	0.9	0.5	0.7	-2.0	0.5	-1.6	0.7	0.4	-0.1	0.4	3.2	0.7	0.6	1.2	2.5	2.8	0.5
Sensitivity / hurt feelings	0.4	0.6	1.7	-0.6	-0.6	-1.2	-0.3	-0.6	0.2	-0.6	-0.8	0.0	-0.9	1.3	-1.0	-0.7	-0.9	-0.8	-0.6	-1.0
Hearing difficulty/problems: Yes	0.4	0.5	2.0	-0.0	0.3	0.9	-1.2	-0.7	-1.0	0.0	0.0	-0.7	0.1	-0.5	0.6	0.4	0.6	1.4	1.1	0.6
Vitamin and mineral supplements	0.4	0.6	2.1	-0.6	-1.0	0.3	-0.7	-0.2	-0.5	-0.6	-0.8	-1.5	-1.0	-0.9	-0.9	-0.8	-0.2	0.3	-1.0	-0.6
Medication: Co-codamol	0.4	0.5	1.5	-0.5	-0.6	-1.1	-1.2	-0.3	-0.8	-0.6	-0.4	-0.9	-0.6	1.2	-0.3	-0.6	-0.8	-0.1	-0.5	-0.4
Fed-up feelings	0.4	0.7	2.1	0.8	1.1	-0.9	0.4	0.9	-0.7	0.9	1.0	0.8	1.0	1.4	0.9	0.9	0.4	-0.3	1.0	0.5
Relative age voice broke	0.4	0.7	5.9	0.5	0.5	-2.4	1.0	-0.1	0.2	0.5	0.7	1.1	0.3	1.0	0.7	0.4	-0.1	0.5	0.7	0.4
Taking other prescription medications	0.4	0.6	4.1	-0.6	-0.6	1.6	-0.4	-0.1	-0.3	-0.6	-0.6	-0.6	-0.2	-2.0	-0.1	-0.5	-0.2	-0.8	-0.5	-0.3
Alcohol usually taken with meals	0.4	0.6	7.4	0.4	0.4	-2.7	-0.0	-0.3	-0.3	0.3	0.2	-0.2	-0.1	0.8	0.5	0.3	-0.1	0.5	-0.6	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	4.2	-0.1	-0.0	0.5	-1.1	-0.8	-1.2	-0.1	0.2	0.0	-0.2	2.1	0.3	-0.1	-0.1	0.3	1.5	-0.3
Hair/balding pattern: Pattern 2	0.4	0.5	3.0	0.3	0.3	1.7	0.5	0.3	0.2	0.4	0.6	0.6	0.1	-0.8	0.8	0.4	0.6	1.0	0.6	0.5
Had other major operations	0.4	0.4	4.7	-0.2	-0.2	1.0	-0.3	-0.8	-2.2	-0.2	0.2	-0.2	-0.3	-0.2	0.0	-0.1	0.3	0.5	0.6	0.3
Allergy	0.4	1.0	7.5	0.3	0.2	-2.7	-0.8	1.1	-0.8	0.3	0.0	-0.9	0.2	2.2	-0.0	0.1	-0.0	0.4	-0.1	-0.3
Exposure to tobacco smoke at home	0.4	0.5	1.3	0.9	0.9	-0.4	1.1	0.5	-0.8	0.9	0.3	0.9	-0.0	0.1	0.4	0.8	0.4	0.7	-0.1	0.9
Birth weight of first child	0.4	0.8	3.5	0.7	0.7	-0.1	0.6	0.7	0.3	0.8	0.4	1.2	1.0	1.9	1.1	0.8	0.3	-0.2	1.5	0.6
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.1	-1.2	-0.6	-0.5	-0.5	0.2	-1.4	-1.0	-0.9	-1.0	-0.4	-1.1	-0.6	-0.8	-0.9	-0.6	-1.4	-0.6
Number of full brothers	0.4	0.5	4.5	-0.5	-0.2	1.7	0.3	0.3	-0.1	-0.4	-0.2	-0.4	-0.1	-2.1	0.2	-0.1	0.3	0.1	-0.5	-0.2
Angina (self-reported)	0.4	0.5	2.3	-0.6	-0.5	-0.7	-1.5	-0.7	-0.2	-0.6	-0.9	-1.2	-0.7	1.1	-0.3	-0.5	-0.7	-0.1	-0.0	-0.5
Medication: Seretide 50 evohaler	0.4	0.4	1.5	0.6	0.6	-0.2	1.2	-0.1	0.9	0.7	0.4	0.7	0.5	-0.6	0.7	0.5	0.2	0.3	-0.9	0.9
Leg fat mass (right)	0.4	1.5	4.8	1.3	1.3	-2.2	0.5	0.9	1.3	1.4	0.9	0.3	0.7	1.6	1.8	1.3	0.5	-1.1	0.9	1.0
Suffer from ‘nerves’	0.4	0.6	2.0	-0.8	-0.7	0.5	-0.4	-1.4	-1.3	-0.8	-0.5	-0.2	-0.7	0.2	-0.5	-0.8	-1.1	-0.3	-0.3	-0.7
Age at last live birth	0.4	0.5	1.3	-1.0	-0.8	-0.4	-0.7	-0.8	-0.7	-1.0	-0.7	-0.7	-0.6	1.1	-0.6	-0.8	-0.8	0.1	-0.7	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.4	0.7	0.7	-0.1	0.4	0.8	-1.2	0.7	0.3	0.9	0.5	0.2	0.5	0.6	0.6	1.1	0.3	0.8
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.9	0.8	0.6	-0.7	-0.3	0.9	0.3	0.7	0.5	-0.4	0.1	-0.9	0.3	0.7	1.3	1.4	-0.2	0.7
Medication: Aspirin	0.4	0.5	2.6	-0.4	-0.1	-0.5	-1.6	-0.7	0.2	-0.2	-0.4	-1.0	-0.1	1.4	0.0	-0.2	-0.2	0.2	1.2	-0.1
Loneliness, isolation	0.4	0.5	1.8	0.7	0.7	-0.6	-0.6	0.1	-0.7	0.6	0.6	0.3	0.9	1.1	0.9	0.5	0.3	1.3	0.5	0.1
Eye problems/disorders: Cataract	0.4	0.4	1.8	0.1	0.5	-1.4	-1.2	-0.9	-0.5	0.1	0.2	-0.7	0.0	0.8	0.8	0.4	-0.1	-0.4	0.8	0.6
Illnesses of father: None of the above (group 1)	0.4	0.5	2.2	0.4	0.1	0.8	1.4	0.3	-1.0	0.3	0.9	1.5	1.2	-0.3	0.7	0.2	0.3	0.3	0.4	0.1
Average weekly champagne plus white wine intake	0.4	0.5	1.6	-0.5	-0.5	-1.3	-1.0	-0.8	0.2	-0.5	-0.7	-1.1	-0.7	-0.1	-0.4	-0.5	-0.7	-1.2	-0.2	-0.6
Financial situation satisfaction	0.4	0.5	2.6	-0.6	-0.5	-0.5	-1.3	-1.1	0.2	-0.5	-0.3	-1.6	-0.3	-0.8	0.2	-0.6	-0.8	-0.5	-0.2	-0.2
Supplements: Fish oil (including cod liver oil)	0.4	0.5	3.5	-0.3	-0.3	-0.3	-1.2	-0.6	-1.0	-0.4	-0.3	-0.1	-0.3	1.9	-0.1	-0.3	-0.4	0.5	0.7	-0.6
High cholesterol (Self-reported)	0.4	0.7	5.9	-0.1	-0.1	-2.2	-0.4	0.3	0.1	-0.1	0.2	-0.0	0.2	2.4	0.1	-0.0	-0.1	0.6	0.8	0.0
Medication: Paracetamol	0.4	0.6	3.6	-0.6	-0.1	-0.6	-0.1	-0.8	-0.3	-0.6	-0.6	0.6	-0.4	1.2	-0.6	-0.4	-1.2	-1.9	0.6	-0.7
Vascular/heart problems diagnosed by doctor	0.4	1.0	5.0	0.3	-0.0	1.0	1.7	1.3	1.2	0.4	0.5	1.0	1.1	-2.2	-0.0	0.1	0.6	0.2	-1.4	-0.1
Irritable Bowel Disease (IBD)	0.3	0.6	2.6	0.2	0.2	0.3	1.1	1.6	0.5	0.3	1.0	0.4	1.3	-1.2	0.7	0.4	0.8	0.3	-0.3	0.8
Ovarian Cancer	0.3	0.4	3.1	0.2	0.1	0.1	0.5	1.8	-0.9	0.2	0.7	0.5	1.2	0.3	0.0	0.1	0.1	-0.0	-0.3	0.1
Body Mass Index (BMI) (2010)	0.3	0.4	2.5	-0.1	0.2	0.1	0.5	0.5	0.7	-0.0	0.3	-0.5	0.6	-1.3	0.2	0.0	-0.4	-1.6	-0.7	-0.1
Coronary Artery Disease (CAD)	0.3	0.4	1.0	-0.3	-0.2	-0.8	-1.0	-0.6	0.7	-0.4	-0.5	-0.9	-0.7	0.1	-0.4	-0.3	-0.7	-0.6	-0.5	-0.5
Fasting Glucose	0.3	0.4	1.4	-0.7	-0.5	-0.3	-1.1	0.7	-0.9	-0.6	0.3	-0.7	1.2	-0.2	0.2	-0.2	0.1	-0.5	0.1	-0.1
Ulcerative Colitis	0.3	0.4	1.3	-0.9	-0.8	0.1	0.1	0.9	0.6	-0.8	0.1	-0.6	0.5	-1.1	-0.4	-0.7	-0.1	-0.0	-1.1	-0.3
Systolic Blood Pressure	0.3	1.3	5.4	-1.3	-1.6	2.3	-0.8	-0.4	-0.6	-1.4	-1.3	-0.3	-1.2	0.2	-1.3	-1.2	-0.6	0.0	0.9	-1.2
Tanning	0.3	3.5	6.1	1.9	1.9	-1.7	1.9	2.5	1.7	2.0	1.9	2.1	2.0	-0.1	1.8	2.1	1.9	1.8	1.4	1.8
Number of treatments/medications taken	0.3	0.5	1.4	-0.9	-0.6	-1.2	-0.4	-0.6	-0.3	-0.9	-0.5	-0.4	-0.6	0.8	-0.5	-0.7	-1.2	-0.7	-0.3	-0.5
Medication for hormone replacement therapy	0.3	0.3	1.3	0.5	0.6	-0.1	1.1	0.1	0.7	0.4	0.4	0.7	-0.2	-1.0	0.5	0.5	0.3	0.1	-0.7	0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.9	0.2	0.1	0.1	1.4	0.1	1.1	0.1	0.2	0.6	-0.2	-0.5	0.2	-0.0	-0.4	-1.0	-0.4	-0.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.8	-0.0	-0.3	0.3	0.2	0.5	-0.2	-0.1	-0.4	-0.4	0.0	-1.4	-0.4	-0.3	-0.3	-1.0	-1.1	-0.2
High blood pressure	0.3	0.8	4.5	0.3	0.6	-1.1	-1.2	-0.7	-1.1	0.2	0.1	-0.4	-0.5	2.1	0.5	0.4	-0.0	0.4	1.6	0.6
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	2.2	0.2	0.2	-0.5	0.4	-0.3	1.5	0.1	0.3	-0.3	-0.4	-0.7	0.9	0.3	0.0	-0.2	-0.7	0.3
Medication: Atenolol	0.3	0.4	4.4	-0.5	-0.0	-0.1	-0.5	-0.1	0.8	-0.4	-0.1	0.3	-0.2	2.1	-0.2	-0.1	-0.3	-0.0	0.7	-0.4
Past tobacco smoking	0.3	0.6	2.3	0.4	0.7	-0.8	-0.6	0.9	-0.4	0.5	0.8	-0.1	0.8	0.7	0.8	0.7	1.0	1.5	0.8	0.7
Had menopause	0.3	0.4	1.1	0.6	0.6	-1.0	-0.4	-1.0	-1.0	0.4	0.5	-0.4	0.0	0.9	0.6	0.5	0.2	0.7	0.4	0.7
Financial difficulties in last 2 years	0.3	0.3	1.5	0.1	-0.4	0.7	-0.7	0.0	-1.2	0.1	-0.2	0.1	-0.1	1.1	-0.0	-0.2	0.1	0.3	1.2	-0.4
Medication: Ramipril	0.3	0.4	1.0	0.8	0.7	-0.2	0.3	0.1	-0.1	0.8	0.3	0.8	0.1	0.6	0.7	0.7	0.5	1.0	0.8	0.5
Fluid intelligence score	0.3	0.6	2.2	-0.3	-0.3	-0.6	-1.2	-1.5	-1.5	-0.4	-0.5	-0.6	-0.4	1.3	-0.1	-0.4	-0.8	-0.3	0.1	-0.3
Father’s age at death	0.3	0.5	1.2	-0.5	-0.7	0.2	0.7	-0.6	0.7	-0.5	-0.8	0.6	-0.8	1.1	-0.8	-0.6	-0.7	-0.7	-0.4	-0.7
Medication: Lansoprazole	0.3	0.4	2.8	-0.2	-0.1	1.7	-0.4	0.3	-0.4	-0.2	0.2	0.3	0.2	0.1	0.4	0.2	0.8	0.9	1.1	0.2
Lung cancer (father)	0.3	0.3	2.0	-0.4	-0.5	-0.1	-0.2	0.1	0.0	-0.5	-0.5	-0.1	-0.0	-0.5	-0.8	-0.6	-0.5	-1.4	-0.5	-0.6
Breastfed as a baby	0.3	0.4	1.2	0.4	0.6	-1.1	0.8	0.9	0.2	0.4	0.4	0.7	0.8	-0.3	0.6	0.5	-0.1	-0.6	-0.4	0.3
Peak expiratory flow (PEF)	0.3	0.6	3.6	-0.3	-0.4	0.1	-1.9	-0.4	-0.5	-0.3	-0.4	-1.0	-0.2	1.4	-0.2	-0.3	0.1	1.3	1.1	-0.1
Qualifications: O levels/GCSEs or equivalent	0.3	0.6	2.7	0.6	0.6	1.0	-0.4	0.5	-1.6	0.7	0.6	0.4	0.6	0.8	0.3	0.5	0.4	0.1	1.2	0.7
Medication: Paracetamol	0.3	0.5	2.6	-0.1	0.4	-1.0	0.0	-0.3	-0.1	-0.1	0.1	0.9	0.1	1.6	0.2	0.2	-0.8	-1.1	1.2	0.0
Health satisfaction	0.3	0.3	0.8	0.6	0.6	0.5	-0.3	-0.1	-0.4	0.7	0.5	-0.1	0.6	-0.8	0.9	0.7	0.8	0.5	0.3	0.8
Medication for pain relief, constipation, heartburn	0.3	0.5	3.2	0.6	0.1	0.0	-0.5	-0.1	-1.8	0.5	0.4	-0.5	0.2	-0.2	0.5	0.3	0.8	1.5	-0.5	0.4
Neck or shoulder pain in last month	0.3	0.4	2.4	0.1	0.4	-0.6	-0.5	0.5	-1.0	0.2	0.1	0.1	0.3	1.5	0.1	0.3	0.1	0.2	1.1	0.3
Overall health rating	0.3	0.6	1.5	-0.8	-0.9	0.8	-0.5	-0.5	-0.5	-0.7	-0.8	-0.8	-0.4	-1.2	-0.7	-0.8	-0.6	-0.4	-1.2	-0.7
Chest pain or discomfort	0.3	0.5	2.2	0.4	0.5	0.1	0.3	0.6	-0.4	0.5	0.9	0.5	1.1	-0.4	0.8	0.6	0.5	1.5	0.8	0.8
Hypertension (Self-reported)	0.3	0.8	4.2	-0.2	0.1	-1.2	-1.4	-0.9	-1.1	-0.2	-0.3	-0.8	-0.7	2.1	0.1	-0.0	-0.5	-0.3	1.2	0.1
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.7	-0.1	-0.2	0.2	1.2	-0.1	1.3	-0.2	-0.2	0.5	-0.8	-1.2	-0.2	-0.1	0.0	-0.4	-0.8	-0.0
Qualifications: nursing, teaching	0.3	0.4	3.2	-0.1	0.0	-0.7	-1.1	-0.3	-0.7	-0.1	-0.3	-0.8	-0.5	1.8	0.1	0.0	-0.2	-0.4	0.7	0.1
Mother’s age at death	0.3	0.4	2.2	-0.5	-0.6	-0.1	-1.5	0.1	0.2	-0.5	-0.5	-1.1	-0.3	1.1	-0.3	-0.5	-0.3	-0.4	0.4	-0.6
Tinnitus: Yes, now most or all of the time	0.3	0.4	3.0	0.3	0.6	-0.7	-0.3	-0.5	-1.7	0.2	-0.1	-0.3	-0.3	-0.0	0.2	0.6	0.4	0.5	0.2	0.8
Illnesses of father: High blood pressure	0.3	0.4	1.3	-0.2	0.3	-0.8	-0.6	-1.1	-0.7	-0.1	-0.2	-0.6	-0.5	1.1	0.1	0.0	-0.6	0.1	1.0	0.5
Risk taking	0.3	0.4	1.6	-0.1	-0.1	0.5	-1.3	-1.3	0.3	-0.1	-0.8	-0.8	-0.8	-0.4	-0.0	-0.1	-0.3	-0.6	0.8	-0.3
Diastolic blood pressure, automated reading	0.3	0.8	1.8	0.8	0.5	0.7	1.3	1.2	1.2	0.8	0.8	0.9	0.9	-1.4	0.8	0.7	1.1	-0.0	0.3	0.7
Myopia	0.3	0.5	1.7	-0.9	-0.6	-0.5	-1.3	-1.2	-0.6	-0.8	-0.7	-1.1	-0.5	0.3	-0.2	-0.5	-0.7	-0.1	0.2	-0.3
Alcohol drinker status: Previous	0.3	0.3	0.9	-0.4	-0.2	-0.9	0.5	-0.3	0.9	-0.4	-0.5	-0.0	-0.5	-0.7	-0.3	-0.3	-0.7	-1.0	-0.5	-0.3
Schizophrenia (2018)	0.2	0.4	3.0	-0.1	-0.2	-0.8	0.9	0.2	1.7	-0.1	0.1	0.8	0.3	-0.6	-0.4	-0.2	-0.3	-0.5	-0.4	-0.5
Worry (Nagel 2018)	0.2	0.3	1.3	-0.2	-0.1	0.4	1.1	-0.7	0.9	-0.2	-0.2	0.6	-0.4	-0.6	-0.1	-0.2	-0.5	-1.1	-0.4	-0.4
Verbal and Numeric Reasoning (VNR)	0.2	0.4	3.0	0.6	0.6	-1.7	0.2	-0.5	0.2	0.6	0.5	0.3	0.3	0.8	0.6	0.4	-0.1	-0.0	-0.2	0.6
Prostate Cancer	0.2	0.3	1.4	-0.0	-0.2	-0.3	-0.8	-1.1	-1.2	-0.2	-0.3	-0.7	-0.2	-0.5	-0.1	-0.2	-0.1	0.6	-0.3	-0.0
Blood Platelet Count	0.2	1.9	4.0	-1.3	-1.6	2.0	0.7	-1.1	-1.5	-1.3	-1.3	1.3	-1.5	1.1	-1.3	-1.4	-1.4	-1.2	0.5	-1.9
Blood Red Count	0.2	2.2	3.9	1.6	1.7	-0.7	1.3	1.2	-0.3	1.7	2.0	1.6	1.6	1.1	1.4	1.7	1.6	0.9	2.0	1.8
Smoking Status	0.2	0.4	1.6	0.2	-0.2	1.3	0.6	-0.4	-0.3	0.1	-0.7	0.3	-0.5	-1.2	-0.3	-0.1	-0.1	-0.8	-1.0	-0.2
Neuroticism	0.2	0.4	1.3	0.8	0.9	-0.3	0.8	-0.3	0.0	0.8	0.7	1.1	0.2	0.8	0.6	0.7	0.3	0.0	0.6	0.3
Hand grip strength (left)	0.2	0.5	1.3	-0.7	-0.7	-0.7	-0.5	-1.1	-0.6	-0.8	-0.5	-1.0	-0.5	0.7	-0.7	-0.8	-1.0	-0.7	-0.6	-0.3
Ever had hysterectomy (womb removed)	0.2	0.3	1.1	0.5	0.7	-0.1	0.6	0.1	0.2	0.5	0.4	1.1	0.4	0.8	0.4	0.4	-0.2	-0.1	0.8	0.4
Trunk fat percentage	0.2	0.8	5.4	0.6	0.6	-2.3	-0.0	0.3	0.5	0.7	0.5	-0.1	0.3	1.6	1.3	0.7	0.1	-0.4	0.6	0.6
Current tobacco smoking	0.2	0.3	2.6	0.2	-0.1	0.4	0.4	0.2	-0.6	0.2	-0.6	0.0	-0.2	-1.6	-0.3	-0.0	0.2	-0.1	-1.3	0.1
Average weekly fortified wine intake	0.2	0.2	0.8	0.3	0.5	0.0	-0.2	-0.8	-0.5	0.2	0.5	0.4	0.2	0.6	0.3	0.4	0.4	0.4	0.9	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.5	-0.6	-0.7	0.8	-1.2	-0.1	0.8	-0.7	-0.9	-0.5	-0.8	1.0	-0.6	-0.7	-0.3	0.5	0.3	-0.9
Stomach or abdominal pain in last month	0.2	0.3	1.6	-0.3	0.0	-1.3	-0.6	-0.3	0.0	-0.3	-0.1	-0.7	-0.5	0.8	-0.4	-0.2	-0.6	-0.0	-0.4	0.0
Medication: Levothyroxine sodium	0.2	0.3	1.6	-0.3	0.1	-1.1	-0.5	0.4	-1.3	-0.3	-0.5	-0.7	0.0	-0.4	0.2	0.0	-0.3	-0.1	-0.6	0.3
Waist circumference	0.2	0.9	4.8	0.8	0.7	-1.8	0.4	0.3	0.1	0.8	0.3	0.5	-0.1	2.2	1.1	0.8	-0.0	-1.1	0.9	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	2.0	0.2	-0.0	1.4	-0.4	0.5	1.4	0.1	-0.1	0.3	-0.2	0.5	0.2	0.1	0.5	0.8	1.0	-0.2
Mouth/teeth dental problems	0.2	0.3	1.1	-0.1	0.2	0.0	0.9	0.5	0.6	-0.1	0.5	0.6	0.2	0.9	-0.6	0.0	-0.2	-1.1	0.6	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	1.8	-0.4	-0.1	-0.9	-0.2	-0.9	-1.3	-0.3	-0.1	-0.0	-0.4	0.9	-0.2	-0.3	-1.0	-0.7	-0.1	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	3.2	0.1	-0.1	1.0	0.0	1.0	0.6	-0.0	0.2	0.8	0.3	1.2	-0.3	0.1	1.0	1.8	0.7	-0.0
Tense / ‘highly strung’	0.2	0.3	1.4	-0.3	-0.2	1.1	-0.8	-1.2	-0.1	-0.3	-0.4	-0.4	-0.5	-1.0	-0.1	-0.2	-0.0	-0.1	0.1	-0.3
Pulse wave reflection index	0.2	0.3	1.8	0.1	0.3	-0.9	-0.4	-0.1	-0.7	0.1	0.3	-0.2	0.7	1.3	0.1	0.1	-0.3	-0.4	0.1	0.3
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.7	0.3	0.3	-0.8	0.4	0.1	-0.6	0.4	0.3	0.6	0.7	0.2	0.7	0.3	0.0	-0.1	0.4	0.5
Headache pain in last month	0.2	0.3	1.3	0.3	0.6	0.4	0.8	0.6	0.3	0.3	0.2	1.1	0.2	0.6	0.2	0.6	0.2	-0.9	1.0	0.4
Gout (self-reported)	0.2	0.2	0.9	0.3	0.0	0.4	-0.6	-0.7	-0.9	0.2	0.2	-0.1	0.4	-0.7	0.3	-0.1	-0.1	0.9	0.1	0.2
Medication: Amlodipine	0.2	0.3	0.7	-0.5	-0.5	-0.8	0.0	0.6	0.7	-0.5	-0.2	-0.3	-0.2	0.8	-0.6	-0.5	-0.5	-0.4	-0.4	-0.5
Birth weight	0.2	0.5	1.8	-0.2	-0.3	-1.3	1.1	-0.1	0.7	-0.1	-0.5	0.6	-0.4	0.9	-0.5	-0.5	-1.1	-1.3	-0.5	-0.7
Leg fat percentage (right)	0.2	0.7	2.6	-0.2	-0.1	-1.6	-1.0	-0.8	-0.3	-0.1	-0.4	-1.1	-0.8	1.5	0.5	-0.1	-0.8	-1.5	0.4	-0.4
Comparative body size at age 10	0.2	0.5	2.6	-0.2	-0.1	-1.1	-0.5	-0.9	0.3	-0.3	-0.4	-1.2	-0.6	0.1	-0.0	-0.3	-0.5	-0.5	-1.6	-0.2
Worry too long after embarrassment	0.2	0.4	1.7	-0.1	0.1	-0.8	0.7	-0.2	1.2	-0.1	-0.4	0.3	-0.7	-0.4	-0.7	-0.1	-0.5	-1.3	-0.7	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.4	0.4	0.3	0.2	1.2	0.2	0.3	0.5	0.5	0.9	0.8	-0.7	0.4	0.3	0.4	-0.1	0.4	0.2
Age at first live birth	0.2	0.4	2.6	-0.5	-0.2	-1.5	-0.3	-0.4	-0.3	-0.6	-0.0	-0.3	0.3	1.6	-0.2	-0.4	-0.6	-0.2	-0.4	0.1
Pulse wave peak to peak time	0.2	0.2	2.1	0.3	0.1	-0.1	0.3	0.5	1.5	0.4	0.2	0.3	-0.1	-0.7	0.0	0.1	0.2	0.2	0.1	-0.1
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.8	-0.2	-0.2	-1.3	0.1	0.1	0.5	-0.1	-0.2	-0.2	0.1	-0.2	0.1	-0.2	-0.7	-0.5	-0.7	-0.2
Mean time to correctly identify matches	0.2	0.3	2.4	0.6	0.2	-0.3	0.1	-0.3	-1.2	0.4	0.2	0.5	0.0	-0.1	-0.0	0.3	0.5	1.6	-0.2	0.3
Heart disease (mother)	0.2	0.2	1.3	0.1	-0.1	1.1	-0.3	-0.4	0.5	-0.0	-0.4	-0.2	-0.6	0.1	0.4	-0.0	-0.1	0.3	0.6	-0.1
Number of full sisters	0.2	0.2	1.1	0.6	0.4	0.2	0.2	1.1	0.3	0.5	0.3	0.4	0.3	-0.0	-0.1	0.4	0.5	0.5	0.2	0.4
Leg pain on walking	0.2	0.3	2.8	-0.0	0.0	1.1	0.1	-0.1	-0.3	-0.0	0.1	-0.4	0.4	-1.7	0.1	0.1	-0.0	-0.8	-0.1	0.4
Supplements: Vitamin C	0.2	0.2	0.7	-0.6	-0.3	0.0	-0.8	-0.8	0.1	-0.7	-0.1	-0.6	-0.4	0.3	0.1	-0.3	-0.3	-0.2	0.3	-0.3
Arm fat percentage (left)	0.2	0.8	2.4	1.0	1.0	-1.4	0.2	0.8	1.0	1.1	0.7	0.1	0.5	1.0	1.6	1.1	0.7	-0.1	0.6	0.9
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.8	0.0	0.2	-0.4	-1.1	-0.8	-1.4	0.1	-0.1	-0.7	-0.1	-0.1	0.6	0.1	-0.3	0.2	0.3	0.4
Mineral and other dietary supplements	0.2	0.3	2.2	0.1	-0.3	1.4	0.3	-0.1	-0.2	0.1	-0.2	-0.2	-0.5	-1.5	-0.4	-0.1	0.3	-0.1	0.1	0.1
Smoking status: Current	0.2	0.4	2.1	0.5	0.2	0.5	1.0	0.6	-0.5	0.5	-0.2	0.6	0.2	-1.4	0.0	0.3	0.4	0.1	-0.9	0.4
Guilty feelings	0.2	0.3	2.0	-0.4	-0.4	0.3	-0.1	-0.1	0.6	-0.4	-0.4	-0.1	-0.5	0.5	-0.7	-0.4	-0.6	-1.4	0.1	-0.6
Medication: Lisinopril	0.2	0.2	1.1	-0.1	0.1	0.5	-0.9	-0.6	0.4	-0.1	-0.4	-1.1	-0.3	-0.7	0.6	0.1	0.1	-0.1	0.1	0.2
Leg fat percentage (left)	0.2	0.6	2.6	-0.1	-0.0	-1.4	-0.8	-0.6	-0.1	0.0	-0.1	-0.9	-0.5	1.6	0.7	0.1	-0.5	-1.3	0.6	-0.2
Number of operations (self-reported)	0.2	0.3	0.9	-0.6	-0.5	-0.4	0.1	-0.5	0.1	-0.7	-0.2	-0.8	-0.8	-0.9	-0.2	-0.5	-0.5	-0.8	-0.9	-0.2
Irritability	0.2	0.3	1.3	-0.2	-0.2	-0.1	-0.8	-0.9	-1.0	-0.2	-0.4	-0.4	-0.3	0.0	-0.1	-0.4	-0.7	-1.1	-0.3	-0.5
Fractured/broken bones in last 5 years	0.2	0.3	0.7	0.4	0.6	-0.9	-0.4	-0.7	-0.5	0.4	0.5	0.1	0.6	0.8	0.6	0.5	0.2	0.3	0.7	0.7
Pain experienced in last month	0.2	0.4	1.7	-0.3	-0.5	-1.2	0.0	-0.0	-1.3	-0.3	0.2	-0.0	0.2	1.2	-0.0	-0.4	-0.1	1.0	-0.1	-0.2
Depression (Nagel 2018)	0.1	0.1	0.7	0.0	0.1	0.7	0.3	-0.9	-0.5	0.0	0.2	0.5	-0.2	0.2	0.6	0.1	-0.1	0.1	-0.2	-0.1
Intelligence (Savage-Jansen 2018)	0.1	0.3	2.4	-0.3	-0.1	-0.5	-0.4	-0.7	-1.5	-0.3	-0.6	-0.2	-0.4	0.6	-0.1	-0.2	-0.6	-0.6	-0.2	-0.0
Neuroticism (Nagel 2018)	0.1	0.2	0.5	0.4	0.6	0.3	0.4	-0.3	0.2	0.5	0.4	0.7	0.2	0.2	0.6	0.4	0.1	-0.6	0.5	0.1
Schizophrenia vs Biploar Disorder	0.1	0.1	0.5	0.1	0.2	-0.7	-0.1	-0.2	0.4	0.1	0.2	0.1	0.5	0.3	0.1	0.1	-0.2	-0.3	-0.3	0.2
Neuroticism (2016)	0.1	0.1	0.6	0.4	0.4	0.1	-0.2	0.0	-0.4	0.3	-0.0	-0.2	-0.0	0.8	0.7	0.3	0.3	0.3	0.1	0.2
Cardiovascular Disease	0.1	0.5	1.1	-0.8	-0.5	0.1	-0.6	-1.0	-0.6	-0.8	-0.7	-0.7	-1.1	0.8	-0.6	-0.7	-0.9	-0.7	0.5	-0.5
Hypothyroidism (self reported)	0.1	0.3	1.4	-0.8	-0.3	-0.7	-0.0	0.4	-1.2	-0.6	-0.4	-0.4	-0.3	-0.4	-0.4	-0.4	-0.5	-0.6	-0.6	-0.2
Relative age of first facial hair	0.1	0.3	1.9	-0.3	-0.1	-1.0	0.8	-1.4	0.2	-0.3	0.0	0.4	-0.5	-0.2	0.1	-0.3	-0.7	0.1	-0.6	-0.1
Systolic blood pressure, automated reading	0.1	0.3	2.4	0.2	-0.1	1.6	-0.2	-0.3	-0.1	0.1	-0.1	0.1	-0.4	-0.4	0.3	0.2	0.7	0.6	1.1	0.3
Hand grip strength (right)	0.1	0.2	0.6	-0.3	-0.3	-0.6	-0.1	-0.8	0.2	-0.4	-0.3	-0.6	-0.7	0.4	-0.6	-0.4	-0.5	-0.5	-0.5	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.6	-0.2	-0.2	0.6	0.4	-0.1	-0.4	-0.1	-0.0	0.8	0.1	0.5	-0.1	-0.1	-0.2	0.0	-0.4	-0.5
Forced vital capacity (FVC)	0.1	0.4	1.1	-0.8	-0.7	0.8	-0.2	-0.0	1.1	-0.8	-0.6	-0.0	-0.1	-0.1	-0.9	-0.7	-0.1	0.4	-0.9	-0.9
Qualifications: None of the above	0.1	0.2	1.1	-0.2	-0.3	-0.1	0.6	0.3	1.0	-0.1	-0.1	0.0	-0.3	-0.2	-0.1	-0.2	-0.2	0.2	-0.4	-0.8
Pain all over the body in last month	0.1	0.1	0.6	-0.0	-0.0	0.5	0.3	-0.1	-0.7	0.0	-0.0	-0.1	-0.2	-0.6	-0.0	-0.0	-0.2	-0.4	-0.0	-0.3
Neuroticism score	0.1	0.1	0.5	0.1	0.3	-0.4	0.3	-0.5	-0.1	0.2	0.1	0.5	-0.1	0.5	-0.1	0.1	-0.3	-0.7	-0.1	-0.2
Arm fat percentage (right)	0.1	0.5	2.0	0.6	0.6	-1.4	-0.1	0.5	0.7	0.7	0.3	-0.2	0.1	1.2	1.2	0.7	0.3	-0.4	0.6	0.5
Worrier / anxious feelings	0.1	0.2	1.2	-0.2	0.2	-0.4	0.4	-0.9	-0.0	-0.0	0.1	0.3	-0.2	0.1	0.2	0.1	-0.4	-1.1	0.2	-0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	1.4	-0.4	-0.4	0.7	-0.8	0.1	0.8	-0.4	-0.4	-0.1	-0.0	1.0	-0.6	-0.4	0.3	1.2	0.2	-0.5
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.6	0.1	0.0	-0.1	0.8	-0.7	0.5	0.1	0.2	0.6	0.1	-0.1	0.2	-0.1	-0.6	-0.8	0.3	0.0
Pulse wave Arterial Stiffness index	0.1	0.2	0.9	0.1	0.3	-0.1	0.3	0.1	-1.0	0.1	0.2	0.4	0.6	0.7	0.3	0.3	0.2	0.1	0.1	0.5
Length of working week for main job	0.1	0.2	0.6	0.3	0.0	-0.5	0.1	0.8	0.7	0.2	0.2	0.1	-0.0	0.7	-0.0	0.1	0.4	0.5	-0.3	-0.2
Hair/balding pattern: Pattern 4	0.1	0.3	1.8	-0.2	-0.3	0.4	-0.9	-0.5	-1.3	-0.3	-0.4	-0.5	-0.1	0.8	-0.1	-0.3	-0.5	-0.4	0.3	-0.3
Forced vital capacity (FVC), Best measure	0.1	0.3	1.2	-0.3	-0.4	0.9	0.2	0.6	0.7	-0.4	-0.2	0.5	-0.1	0.3	-0.6	-0.2	0.6	1.1	-0.4	-0.4
Body fat percentage	0.1	0.5	3.9	0.2	0.2	-2.0	-0.4	-0.0	0.2	0.3	0.1	-0.5	-0.2	1.6	0.9	0.3	-0.2	-0.8	0.5	0.1
Eye problems/disorders: None of the above	0.1	0.2	1.2	-0.3	-0.5	1.1	0.1	-0.2	-0.4	-0.2	-0.2	0.3	0.3	0.1	-0.2	-0.5	-0.3	0.1	0.2	-0.4
Alcohol intake frequency.	0.1	0.1	1.2	0.3	0.4	-1.1	0.2	0.4	0.3	0.3	-0.1	-0.1	0.0	0.4	0.2	0.3	-0.1	-0.3	-0.0	0.1
Illnesses of siblings: Diabetes	0.1	0.2	0.8	-0.0	-0.1	0.0	0.3	-0.2	-0.8	-0.1	-0.3	0.6	-0.2	0.9	-0.1	-0.1	-0.3	-0.4	0.9	-0.1
Mood swings	0.1	0.3	1.3	0.0	0.4	-0.8	0.1	-0.4	-0.7	0.1	0.5	0.5	0.4	1.1	0.0	0.1	-0.4	-0.9	-0.0	-0.2
Long-standing illness, disability or infirmity	0.1	0.2	0.7	0.4	0.5	-0.5	0.1	0.3	-0.4	0.4	0.3	0.0	0.2	-0.4	0.6	0.5	0.3	0.8	-0.2	0.7
Pain type(s) experienced in last month: Hip pain	0.1	0.2	1.5	-0.3	-0.3	1.2	0.2	-0.7	-0.0	-0.3	-0.1	0.3	-0.2	0.3	0.1	-0.1	-0.3	-0.5	0.4	0.1
Basal cell carcinoma (self-reported)	0.1	0.1	0.5	-0.2	-0.1	-0.7	0.7	0.5	0.2	-0.1	0.0	0.4	0.1	0.2	0.1	-0.1	-0.4	-0.2	-0.1	-0.1
Blood White Count	0.0	0.3	1.7	0.1	-0.5	1.1	-0.6	-0.2	-1.3	0.1	-0.5	-0.1	0.1	0.1	-0.2	-0.4	0.0	0.5	0.5	-0.3
Hair Pigment	0.0	1.2	4.3	0.5	0.3	1.8	2.0	1.3	1.3	0.5	0.6	2.1	0.3	-0.1	-0.1	0.4	1.5	1.7	0.2	0.3

Hub : Genes

NUDT6

Models

Trait associations