[Hub]/) : Traits : Waist Hip Ratio (WHR) :

chr6:79,927,081-81,872,212

Best TWAS P=1.41e-16 · Best GWAS P=2.52e-23 conditioned to 0.000193

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TTK 0.07 0.00 bslmm 472 0.02 3.8e-03 -2.3 -5.4 6.0e-08 0.06 0.13 0.05 FALSE
2 GTEx Brain Cerebellum RP11-250B2.5 0.43 0.11 lasso 5 0.14 4.7e-05 -5.7 -7.8 4.3e-15 0.09 0.38 0.14 TRUE
3 GTEx Breast Mammary Tissue (Male) RP11-250B2.5 0.12 0.09 lasso 4 0.08 7.5e-03 4.7 5.8 5.3e-09 -0.38 0.06 0.23 FALSE
4 GTEx Breast Mammary Tissue (Male) RP11-250B2.6 0.12 0.00 enet 10 0.00 3.9e-01 7.7 5.8 5.8e-09 -0.37 0.06 0.07 FALSE
5 GTEx Cells EBV-transformed lymphocytes RP11-250B2.6 0.21 0.03 enet 37 0.13 4.7e-05 2.9 -8.3 1.4e-16 0.30 0.11 0.28 TRUE
6 GTEx Cells Transformed fibroblasts BCKDHB 0.16 0.02 enet 42 0.04 3.7e-04 3.4 6.1 8.1e-10 0.04 0.68 0.02 FALSE
7 GTEx Colon Transverse RP11-250B2.3 0.17 0.12 enet 15 0.08 1.1e-04 2.7 6.0 2.0e-09 -0.18 0.40 0.15 FALSE
8 GTEx Heart Atrial Appendage RP11-250B2.6 0.20 0.00 enet 17 0.03 2.6e-02 -3.5 -6.4 1.6e-10 0.32 0.10 0.06 FALSE
9 GTEx Nerve Tibial RP11-250B2.3 0.16 0.05 enet 9 0.05 3.5e-04 7.0 5.2 1.7e-07 -0.22 0.51 0.02 FALSE
10 GTEx Testis ELOVL4 0.31 0.19 lasso 7 0.18 1.9e-08 -6.3 -6.3 3.3e-10 0.09 0.96 0.01 TRUE
11 GTEx Testis RP11-250B2.5 0.13 0.17 lasso 3 0.14 7.0e-07 -5.8 -5.3 1.4e-07 -0.25 0.81 0.02 FALSE
12 GTEx Thyroid BCKDHB 0.17 0.06 lasso 8 0.10 3.4e-08 3.4 5.6 2.5e-08 0.17 1.00 0.00 FALSE
13 GTEx Thyroid RP11-250B2.3 0.12 0.00 enet 25 0.01 2.5e-02 7.0 7.0 2.5e-12 -0.36 0.13 0.52 TRUE
14 METSIM Adipose RP11-250B2.5 0.03 0.03 lasso 4 0.01 3.5e-03 7.1 7.1 1.5e-12 -0.30 0.34 0.10 TRUE
15 ROSMAP Brain Pre-frontal Cortex RP11-250B2.5 0.09 0.06 lasso 7 0.08 4.6e-11 5.1 6.4 1.3e-10 -0.34 1.00 0.00 FALSE
16 The Cancer Genome Atlas Testicular Germ Cell Tumors BCKDHB 0.19 0.02 blup 137 0.06 2.6e-03 2.9 5.7 1.1e-08 -0.05 0.03 0.05 FALSE