[Hub]/) : Traits : Waist Hip Ratio (WHR) :

chr8:70,788,124-72,974,329

Best TWAS P=1.67e-13 · Best GWAS P=7.33e-32 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LACTB2 0.07 0.09 lasso 5 0.08 3.7e-10 6.0 -5.8 8.5e-09 -0.01 0.19 0.81 FALSE
2 CommonMind Brain Pre-frontal Cortex XKR9 0.26 0.52 lasso 13 0.51 1.6e-72 5.6 5.8 6.8e-09 0.01 0.74 0.26 FALSE
3 GTEx Artery Tibial LACTB2 0.17 0.02 enet 26 0.06 1.0e-05 -5.5 -5.4 6.6e-08 0.04 0.09 0.90 FALSE
4 GTEx Cells Transformed fibroblasts TRAM1 0.06 0.03 enet 17 0.03 3.0e-03 -6.5 -5.7 1.3e-08 0.03 0.03 0.96 TRUE
5 GTEx Cells Transformed fibroblasts LACTB2 0.05 0.00 enet 4 0.02 1.6e-02 5.4 -5.7 1.4e-08 -0.03 0.20 0.48 FALSE
6 GTEx Nerve Tibial LACTB2 0.07 0.06 lasso 2 0.04 1.5e-03 5.3 -5.2 1.7e-07 0.00 0.41 0.54 FALSE
7 GTEx Pancreas LACTB2 0.13 0.11 enet 19 0.05 3.3e-03 5.3 -5.6 2.8e-08 -0.02 0.21 0.72 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic LACTB2 0.07 0.07 lasso 2 0.07 7.5e-05 6.0 -6.1 1.1e-09 -0.01 0.13 0.85 TRUE
9 GTEx Skin Sun Exposed Lower leg LACTB2 0.05 0.03 lasso 3 0.04 4.6e-04 6.0 -5.3 8.8e-08 -0.01 0.18 0.79 FALSE
10 METSIM Adipose XKR9 0.17 0.37 enet 33 0.38 8.6e-60 5.6 -5.4 7.6e-08 -0.02 0.75 0.25 FALSE
11 ROSMAP Brain Pre-frontal Cortex EYA1 0.13 0.05 blup 567 0.08 5.1e-10 11.7 7.4 1.7e-13 0.62 0.00 1.00 TRUE
12 ROSMAP Brain Pre-frontal Cortex XKR9 0.22 0.38 bslmm 366 0.40 1.0e-54 5.6 -6.5 7.1e-11 0.00 0.72 0.28 TRUE
13 YFS Blood TRAM1 0.02 0.01 enet 22 0.02 8.1e-07 6.0 -5.9 4.0e-09 0.06 0.15 0.80 TRUE
14 The Cancer Genome Atlas Breast Invasive Carcinoma XKR9 0.25 0.51 lasso 8 0.51 2.4e-123 5.3 -5.3 1.4e-07 -0.01 0.07 0.93 FALSE
15 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma XKR9 0.35 0.42 enet 12 0.42 3.5e-22 5.6 -5.7 1.1e-08 -0.01 0.05 0.95 FALSE
16 The Cancer Genome Atlas Colon Adenocarcinoma XKR9 0.32 0.44 lasso 12 0.45 7.9e-29 5.3 -5.3 9.3e-08 -0.01 0.06 0.94 FALSE
17 The Cancer Genome Atlas Glioblastoma Multiforme XKR9 0.18 0.15 enet 19 0.20 1.1e-06 5.6 -5.8 5.0e-09 -0.01 0.05 0.94 FALSE
18 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma XKR9 0.21 0.38 lasso 6 0.38 4.6e-45 5.6 -5.2 2.6e-07 -0.01 0.06 0.94 FALSE
19 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma XKR9 0.34 0.51 enet 16 0.51 9.7e-66 5.3 -5.7 1.3e-08 -0.01 0.06 0.94 FALSE
20 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma XKR9 0.45 0.55 lasso 3 0.57 1.2e-38 5.3 -5.4 6.7e-08 -0.01 0.07 0.93 FALSE
21 The Cancer Genome Atlas Brain Lower Grade Glioma XKR9 0.18 0.35 enet 13 0.34 7.7e-40 5.6 -5.2 1.5e-07 -0.01 0.05 0.95 FALSE
22 The Cancer Genome Atlas Liver Hepatocellular Carcinoma XKR9 0.40 0.46 lasso 5 0.46 5.5e-24 5.6 -5.4 5.1e-08 -0.01 0.06 0.94 FALSE
23 The Cancer Genome Atlas Lung Squamous Cell Carcinoma XKR9 0.28 0.46 lasso 9 0.46 1.7e-57 5.6 -5.3 1.5e-07 -0.01 0.06 0.94 FALSE
24 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma XKR9 0.32 0.53 lasso 7 0.52 6.5e-40 5.6 -5.5 3.7e-08 -0.01 0.06 0.94 FALSE
25 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma XKR9 0.47 0.58 enet 13 0.59 1.5e-28 5.3 -5.3 1.1e-07 -0.02 0.06 0.94 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma XKR9 0.51 0.62 lasso 7 0.64 4.7e-86 5.5 -5.2 2.4e-07 -0.01 0.06 0.94 FALSE
27 The Cancer Genome Atlas Stomach Adenocarcinoma XKR9 0.22 0.26 enet 13 0.24 1.8e-17 5.6 -5.5 4.2e-08 0.00 0.05 0.95 FALSE
28 The Cancer Genome Atlas Testicular Germ Cell Tumors XKR9 0.33 0.33 enet 21 0.34 9.6e-13 5.6 -5.6 1.6e-08 -0.01 0.06 0.94 FALSE
29 The Cancer Genome Atlas Thyroid Carcinoma LACTB2 0.03 0.01 enet 5 0.01 6.1e-02 5.6 -6.7 2.9e-11 -0.01 0.02 0.64 FALSE
30 The Cancer Genome Atlas Thyroid Carcinoma XKR9 0.38 0.55 lasso 9 0.56 2.5e-65 5.6 -5.6 2.4e-08 -0.01 0.06 0.94 FALSE
31 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma XKR9 0.24 0.24 lasso 4 0.25 1.3e-07 5.6 -5.9 4.7e-09 -0.01 0.03 0.97 TRUE