[Hub]/) : Traits : Verbal and Numeric Reasoning (VNR) : ← →

chr2:99,468,341-101,731,705

Best TWAS P=8.34e-10 · Best GWAS P=3.4e-11 conditioned to 0.0013

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AFF3 0.31 0.24 enet 32 0.25 9.2e-31 4.9 5.7 1.2e-08 0.53 0.98 0.02 FALSE
2 GTEx Adrenal Gland CHST10 0.18 0.04 lasso 4 0.05 5.6e-03 5.3 -6.1 8.3e-10 -0.71 0.27 0.29 TRUE
3 GTEx Artery Tibial AFF3 0.06 0.04 enet 6 0.04 4.3e-04 -4.8 5.4 7.1e-08 0.65 0.15 0.80 FALSE
4 GTEx Cells EBV-transformed lymphocytes CHST10 0.25 0.15 lasso 4 0.12 9.1e-05 -6.1 6.0 2.1e-09 0.69 0.15 0.63 FALSE
5 GTEx Muscle Skeletal LONRF2 0.07 0.08 lasso 4 0.08 2.5e-08 5.4 5.4 7.3e-08 0.58 0.73 0.27 FALSE
6 GTEx Skin Sun Exposed Lower leg LONRF2 0.05 0.03 lasso 2 0.02 9.3e-03 -5.5 5.6 1.8e-08 0.60 0.29 0.20 FALSE
7 GTEx Thyroid CHST10 0.05 0.05 lasso 5 0.03 2.6e-03 5.3 5.7 1.5e-08 0.64 0.20 0.69 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LONRF2 0.06 0.04 blup 69 0.04 3.4e-05 -5.5 5.9 4.3e-09 0.72 0.21 0.78 FALSE
9 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LONRF2 0.05 0.08 lasso 2 0.08 2.9e-05 -5.9 5.8 5.0e-09 0.72 0.07 0.71 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma AFF3 0.06 0.00 blup 244 0.01 1.3e-02 -3.5 5.5 3.2e-08 0.48 0.08 0.15 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma CHST10 0.04 0.04 lasso 3 0.03 2.6e-04 5.3 5.3 9.5e-08 0.56 0.03 0.95 FALSE