[Hub]/) : Traits : Blood White Count :

chr9:129,486,982-132,180,229

Best TWAS P=1.63e-18 · Best GWAS P=1.68e-18 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere RP11-395P17.3 0.32 0.03 lasso 4 0.06 1.1e-02 2.4 5.6 2.1e-08 0.02 0.05 0.13 TRUE
2 GTEx Breast Mammary Tissue (Male) RPL12 0.15 0.14 lasso 3 0.17 1.1e-04 5.3 -5.3 8.8e-08 -0.05 0.09 0.16 TRUE
3 GTEx Colon Transverse PKN3 0.37 0.35 lasso 3 0.34 6.2e-17 -8.8 -8.7 2.6e-18 1.00 0.00 1.00 FALSE
4 GTEx Heart Atrial Appendage ZNF79 0.12 0.10 lasso 1 0.08 1.7e-04 5.2 5.2 1.9e-07 0.06 0.23 0.18 FALSE
5 GTEx Liver PKN3 0.63 0.52 lasso 4 0.50 5.1e-16 -8.8 -8.8 1.6e-18 1.00 0.00 1.00 TRUE
6 GTEx Muscle Skeletal LRSAM1 0.09 0.11 lasso 2 0.11 3.8e-11 5.2 -5.2 2.2e-07 -0.07 0.69 0.31 FALSE
7 GTEx Skin Sun Exposed Lower leg ZNF79 0.09 0.04 lasso 5 0.04 2.7e-04 4.9 5.3 1.1e-07 0.07 0.75 0.16 FALSE
8 GTEx Small Intestine Terminal Ileum PKN3 0.28 0.39 lasso 2 0.36 5.6e-09 -8.8 -8.8 1.7e-18 1.00 0.00 1.00 FALSE
9 GTEx Stomach PKN3 0.22 0.26 lasso 2 0.25 4.4e-12 -8.8 -8.8 1.7e-18 1.00 0.00 1.00 FALSE
10 YFS Blood PKN3 0.07 0.05 lasso 3 0.05 1.3e-16 -5.3 -5.5 2.9e-08 0.65 0.00 1.00 FALSE
11 The Cancer Genome Atlas Bladder Urothelial Carcinoma ZNF79 0.08 0.09 enet 15 0.10 1.1e-08 5.1 5.3 1.4e-07 0.07 0.01 0.99 FALSE
12 The Cancer Genome Atlas Colon Adenocarcinoma AK1 0.10 0.03 enet 7 0.03 4.2e-03 4.2 -6.4 1.5e-10 0.03 0.01 0.88 TRUE
13 The Cancer Genome Atlas Colon Adenocarcinoma ZNF79 0.12 0.08 enet 5 0.11 7.9e-07 5.2 5.2 1.9e-07 0.07 0.01 0.99 FALSE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ZNF79 0.07 0.07 blup 50 0.06 1.7e-07 4.4 5.1 3.0e-07 0.09 0.05 0.93 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C9orf16 0.09 0.03 blup 34 0.04 2.5e-03 2.9 5.3 8.9e-08 -0.04 0.00 0.15 TRUE
16 The Cancer Genome Atlas Brain Lower Grade Glioma ZNF79 0.05 0.03 lasso 6 0.04 6.5e-05 5.2 5.2 1.8e-07 0.07 0.01 0.98 FALSE
17 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PKN3 0.07 0.03 enet 5 0.05 3.3e-03 -8.8 -7.6 2.6e-14 0.90 0.00 0.94 FALSE
18 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DPM2 0.03 0.01 blup 29 0.02 5.3e-03 6.3 5.1 2.8e-07 -0.01 0.00 0.84 FALSE
19 The Cancer Genome Atlas Pancreatic Adenocarcinoma AK1 0.17 0.01 enet 7 0.05 3.3e-03 5.6 -6.2 4.2e-10 0.07 0.00 0.82 FALSE
20 The Cancer Genome Atlas Thyroid Carcinoma ZNF79 0.04 0.04 lasso 3 0.04 9.1e-05 5.1 5.1 2.9e-07 0.07 0.01 0.98 FALSE