Hub : Genes

TPCN2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1710 0.0410 1.8e-09 0.102 0.092 0.091 0.090 0.096 2.0e-12 2.6e-11 3.2e-11 4.3e-11 9.2e-12
2 GTEx Adipose Subcutaneous 0.1770 0.0510 1.1e-05 0.015 NA 0.122 NA 0.076 2.1e-02 NA 3.5e-10 NA 8.1e-07
3 GTEx Artery Aorta 0.2100 0.0720 5.4e-04 0.169 NA 0.132 NA 0.157 1.3e-09 NA 1.0e-07 NA 5.5e-09
4 GTEx Artery Tibial 0.3675 0.0603 5.4e-12 0.122 NA 0.223 NA 0.195 8.7e-10 NA 2.3e-17 NA 3.3e-15
5 GTEx Breast Mammary Tissue 0.2110 0.0800 6.4e-03 0.010 NA 0.115 NA 0.014 9.3e-02 NA 1.7e-06 NA 5.9e-02
6 GTEx Breast Mammary Tissue (Male) 0.0144 0.0699 4.4e-01 0.018 NA 0.004 NA -0.012 1.2e-01 NA 2.5e-01 NA 7.8e-01
7 GTEx Breast Mammary Tissue (Female) 0.1130 0.0818 1.1e-01 -0.007 NA 0.027 NA -0.005 6.0e-01 NA 5.2e-02 NA 5.0e-01
8 GTEx Cells Transformed fibroblasts 0.2220 0.0620 3.0e-04 0.059 NA 0.101 NA 0.084 3.3e-05 NA 5.2e-08 NA 7.0e-07
9 GTEx Esophagus Mucosa 0.2020 0.0590 3.1e-05 0.074 NA 0.061 NA 0.062 1.2e-05 NA 6.7e-05 NA 5.6e-05
10 GTEx Esophagus Muscularis 0.2270 0.0940 1.2e-03 0.005 NA -0.005 NA 0.012 1.5e-01 NA 9.8e-01 NA 6.0e-02
11 GTEx Muscle Skeletal 0.1939 0.0492 2.0e-07 0.109 NA 0.132 NA 0.090 7.7e-11 NA 6.8e-13 NA 3.6e-09
12 GTEx Nerve Tibial 0.2795 0.0621 2.9e-08 0.131 NA 0.169 NA 0.040 1.6e-09 NA 4.9e-12 NA 8.2e-04
13 GTEx Skin Not Sun Exposed Suprapubic 0.1910 0.0580 2.2e-04 0.099 NA 0.083 NA 0.103 4.6e-06 NA 2.6e-05 NA 3.0e-06
14 GTEx Skin Sun Exposed Lower leg 0.0890 0.0410 6.6e-03 0.000 NA 0.033 NA 0.034 3.0e-01 NA 8.4e-04 NA 8.0e-04
15 GTEx Testis 0.2640 0.0960 1.9e-03 0.046 NA 0.023 NA 0.068 4.1e-03 NA 3.4e-02 NA 5.9e-04
16 GTEx Thyroid 0.1460 0.0520 5.4e-04 0.081 NA 0.061 NA 0.004 8.9e-07 NA 1.9e-05 NA 1.5e-01
17 METSIM Adipose 0.4159 0.0448 0.0e+00 0.286 0.308 0.335 0.328 0.320 3.5e-43 6.4e-47 1.1e-51 1.6e-50 3.7e-49
18 NTR Blood 0.0805 0.0178 2.1e-15 0.056 0.050 0.053 0.048 0.031 1.9e-17 8.3e-16 9.1e-17 2.5e-15 3.1e-10
19 TCGA Brain Lower Grade Glioma 0.0605 0.0260 4.8e-04 0.043 0.044 0.033 NA 0.041 1.0e-05 8.4e-06 1.1e-04 NA 1.8e-05
20 TCGA Pheochromocytoma and Paraganglioma 0.1760 0.0910 6.1e-03 0.050 0.003 -0.006 NA 0.000 4.8e-03 2.4e-01 6.5e-01 NA 3.3e-01
21 TCGA Thyroid Carcinoma 0.1110 0.0420 1.4e-05 0.054 0.028 0.047 NA 0.049 5.6e-06 8.1e-04 2.1e-05 NA 1.5e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bipolar Disorder (2018) 0.4 0.6 2.5 -0.3 -0.4 1.3 0.3 0.1 0.0 0.8 0.3 0.8 -0.7 0.9 1.6 1.2 0.9 1.0 0.1 -0.7 -0.4 -0.2 -0.6 0.8
Bipolar Disorder or Schizophrenia 0.5 1.3 4.2 -1.2 -0.2 1.4 0.9 0.0 0.0 -0.1 1.2 1.2 0.1 1.3 2.1 1.0 0.2 0.0 1.1 -2.0 -1.6 -1.8 -1.3 -0.0
Depressed Affect (Nagel 2018) 0.2 0.3 1.4 1.0 0.9 0.1 -0.1 0.5 0.0 0.6 -0.5 0.1 0.0 -0.3 0.6 -0.1 0.8 0.6 -0.9 1.2 0.2 0.6 -0.0 -0.3
Depression (Nagel 2018) 0.8 1.1 3.3 -0.5 1.8 1.3 1.5 1.4 0.0 0.7 0.4 1.1 0.3 0.9 1.8 1.3 1.0 1.7 0.3 0.4 -1.0 -0.7 -1.0 0.8
Intelligence (Savage-Jansen 2018) 0.6 1.9 4.8 1.6 -0.4 -2.0 -1.1 0.3 0.0 -0.4 -0.7 -2.2 1.6 -1.7 -0.8 -2.0 -1.3 -2.2 -1.5 0.2 1.3 1.6 1.6 -1.1
Neuroticism (Nagel 2018) 0.2 0.4 1.6 1.0 0.5 0.1 -0.4 0.4 0.0 0.7 -0.2 0.2 0.3 -0.7 0.5 -0.1 1.2 0.7 -1.1 0.5 0.7 0.5 0.4 -0.6
Schizophrenia (2018) 0.6 1.3 4.3 -1.4 0.1 0.7 1.2 -0.1 0.0 -0.8 1.3 1.0 0.7 0.9 1.4 0.2 -0.6 -0.8 1.9 -1.9 -1.7 -2.1 -1.2 -0.7
Schizophrenia vs Biploar Disorder 0.4 0.5 2.5 -0.2 -0.0 -0.0 0.9 -0.5 0.0 -1.6 -0.4 0.0 0.3 -0.3 -0.1 -0.4 -0.2 -0.6 0.6 -1.2 -0.8 -1.6 -0.4 -1.2
Worry (Nagel 2018) 0.1 0.3 1.8 0.1 0.3 0.3 -0.0 -0.0 0.0 0.4 0.3 0.3 -0.6 -0.1 0.6 0.1 1.1 1.3 -0.6 0.2 0.3 -0.5 0.4 -0.0
Alzheimer’s Disease (in mother) 0.4 0.5 3.4 -0.3 -0.1 -0.1 0.1 1.4 0.0 1.1 1.9 0.1 -1.1 -0.1 -0.2 -0.3 -0.1 -0.7 -0.8 0.5 0.4 0.7 0.2 -0.2
Alzheimer’s Disease (in father) 1.0 1.0 5.2 -0.2 -0.7 -0.3 -1.7 0.1 0.0 1.3 -1.5 -0.2 2.3 0.5 0.6 0.1 -0.7 -1.3 -1.1 0.6 -0.3 1.5 0.3 1.5
Alzheimer’s Disease (including proxy) 0.6 0.9 5.2 -0.0 -1.2 -0.9 -1.5 0.7 0.0 1.1 0.4 -0.6 0.3 -0.1 -0.2 -0.8 -1.0 -2.3 -1.5 0.2 0.6 1.6 -0.5 0.6
Crohns Disease (2017) 0.3 0.6 2.1 0.6 0.7 -0.6 -0.1 -0.8 0.0 -0.9 -0.5 -0.7 0.2 -0.9 -1.5 -0.9 0.5 -0.3 -1.2 -0.7 -0.3 -1.0 0.5 -1.1
Irritable Bowel Disease (IBD) 0.8 2.0 4.8 1.8 0.8 -1.7 -1.2 -1.3 0.0 -1.4 -1.2 -2.2 -0.3 -2.2 -1.9 -1.8 0.1 -0.5 -1.4 -0.7 0.7 -0.2 1.8 -2.2
Ulcerative Colitis (UC) 1.6 3.0 8.3 2.4 0.6 -2.3 -1.9 -1.2 0.0 -1.5 -1.3 -2.9 -0.5 -2.7 -2.0 -2.4 -0.7 -0.5 -1.0 -0.5 1.7 0.5 2.5 -2.4
Major Depression (MDD) 0.2 0.2 0.7 0.0 0.6 0.0 0.5 0.6 0.0 0.2 0.0 0.1 0.8 0.0 0.6 0.2 0.8 0.8 -0.1 0.8 0.0 -0.3 -0.1 0.0
Reaction Time 1.6 3.0 11.2 -1.8 1.0 2.1 2.4 2.1 0.0 1.5 1.3 1.8 -1.2 1.8 1.8 1.8 0.5 2.1 1.7 0.2 -1.6 -1.8 -3.4 1.1
Verbal and Numeric Reasoning (VNR) 1.1 2.7 6.8 2.0 -1.4 -1.9 -1.9 -0.4 0.0 -0.6 -1.9 -2.6 2.0 -1.8 -1.0 -1.6 -1.5 -2.0 -1.5 -0.2 1.7 2.4 1.9 -0.6
Breast Cancer 1.1 2.6 8.6 -1.5 0.8 2.7 1.9 -0.8 0.0 -0.0 1.0 1.0 -0.8 0.5 1.9 2.1 2.7 2.1 -0.0 -1.0 -0.7 -2.9 -2.6 -0.1
Ovarian Cancer 3.0 4.0 11.4 -2.1 2.1 2.1 2.4 2.8 0.0 1.9 1.9 2.4 -0.1 2.2 3.4 2.2 2.5 1.7 2.1 0.5 -2.4 -1.3 -0.8 1.6
Prostate Cancer 2.7 3.8 24.5 -0.3 -0.4 0.5 -2.2 -2.7 0.0 1.1 0.0 0.4 3.1 1.4 0.3 1.7 0.6 1.7 -0.6 1.5 0.4 3.2 4.9 3.4
Age at First Birth 0.4 0.6 3.8 -0.6 -0.1 -0.2 0.2 -2.0 0.0 -0.6 -0.7 0.3 -0.2 0.3 -0.1 -0.6 -0.7 -1.1 -0.3 -0.9 -0.8 -1.2 -1.0 -0.7
Bipolar Disorder (2011) 0.9 0.8 2.7 1.0 0.3 -0.9 -1.6 0.4 0.0 0.8 -0.7 -1.0 0.0 -0.6 -0.6 -0.7 -1.0 0.1 -1.6 1.1 1.6 1.1 1.1 0.1
Body Mass Index (BMI) (2010) 0.2 0.3 1.0 0.7 -0.2 -0.1 -0.3 0.3 0.0 -0.7 -0.5 -0.5 0.4 -0.8 0.1 -0.1 -0.8 -1.0 0.7 -0.4 0.1 0.3 0.1 -1.0
Coronary Artery Disease (CAD) 0.2 0.3 1.1 0.7 0.3 0.3 -0.1 -0.4 0.0 0.4 -0.3 0.1 0.3 -0.1 0.7 0.7 -0.2 0.8 -0.6 0.5 0.4 0.8 1.0 0.4
Crohns Disease (2012) 0.2 0.4 2.2 -0.0 -0.3 -0.3 -0.2 -1.5 0.0 -0.7 -0.7 -0.5 -0.3 -0.1 -1.3 -0.4 0.2 -0.0 -0.5 -1.0 0.1 -1.0 0.3 -0.5
Mean Putamen Volume 0.1 0.2 0.7 -0.8 0.1 0.5 0.5 0.4 0.0 0.6 0.2 0.2 0.0 0.7 0.7 0.3 0.3 0.1 0.1 0.1 -0.5 -0.3 -0.3 0.4
Fasting Glucose 0.7 0.9 3.5 -1.0 -0.5 1.0 1.0 -0.8 0.0 -1.5 0.3 1.1 0.0 0.7 -0.2 0.6 0.4 0.4 0.8 -1.9 -0.5 -1.8 -1.6 -0.3
HbA1C 0.5 0.6 2.9 -0.4 0.3 0.0 0.7 -0.2 0.0 0.8 -0.3 0.8 1.7 0.6 0.5 0.9 1.5 1.0 0.9 0.5 0.3 0.1 -0.4 1.2
HDL Cholesterol 0.2 0.3 2.2 -1.0 -0.6 0.3 0.2 -0.1 0.0 0.6 1.1 0.2 -0.2 0.7 0.2 -0.0 -0.3 -0.0 0.5 -0.4 -0.2 -1.0 -1.5 0.0
LDL Cholesterol 0.4 0.6 3.5 -0.2 -1.9 1.0 -0.1 -0.5 0.0 -0.3 0.8 0.6 -0.6 0.0 0.7 1.0 0.6 1.3 -0.4 -1.1 0.4 -0.5 0.3 0.0
Lupus 2.9 4.5 9.7 2.1 -0.7 -3.1 -2.3 -0.4 0.0 -0.8 -1.8 -2.7 1.8 -2.0 -2.2 -2.9 -3.1 -2.7 -2.1 0.1 2.0 2.7 2.9 -1.1
Neuroticism (2016) 0.5 0.7 3.5 0.7 -0.5 -0.5 0.0 1.4 0.0 0.4 1.9 -0.2 -0.2 -0.9 -0.7 -0.5 0.2 0.2 -0.5 -0.3 1.6 1.1 1.5 -0.6
Primary Biliary Cirrhosis 1.2 1.6 6.5 1.2 -1.0 -1.6 -1.0 -1.2 0.0 -1.8 -0.7 -1.3 -0.6 -1.2 -1.8 -1.8 -2.5 -0.8 -0.4 -1.3 1.0 -0.0 1.4 -1.2
Rheumatoid Arthritis 0.8 1.2 3.5 0.8 1.9 -1.8 -0.9 0.3 0.0 0.7 -1.0 -1.5 0.7 -0.6 -0.3 -1.5 -0.6 -0.9 -1.3 1.7 1.0 1.2 0.9 0.4
Schizophrenia (2014) 0.7 1.5 7.4 -0.8 -0.9 0.9 1.1 -0.8 0.0 -1.8 1.3 0.9 -0.3 0.3 1.1 0.2 -0.1 -0.2 1.4 -2.7 -1.0 -2.3 -1.4 -1.4
Triglycerides 2.1 3.5 8.6 -2.0 0.9 2.7 2.0 1.1 0.0 1.1 -0.1 2.5 -0.3 2.1 2.7 2.9 2.6 2.4 1.3 -0.1 -2.9 -1.6 -1.1 1.7
Type 2 Diabetes (T2D) (2012) 1.1 1.3 5.0 -1.0 -1.4 1.0 0.0 -0.1 0.0 -0.2 0.4 1.1 -0.3 1.3 1.7 1.1 1.2 1.0 1.5 -1.4 -1.6 -1.0 -2.2 0.9
Ulcerative Colitis 2.0 2.9 8.1 2.4 -0.1 -2.2 -2.0 -1.4 0.0 -1.4 -2.0 -2.9 -1.4 -2.7 -2.0 -2.4 -0.8 -0.5 -0.8 -0.6 2.0 0.1 1.4 -2.0
Blood Eosinophil Count 0.4 3.4 11.0 1.8 0.1 -2.4 -1.6 -1.4 0.0 -2.1 -1.9 -1.9 3.3 -1.9 -2.5 -2.1 -1.1 -1.5 -1.8 -0.2 1.5 0.8 3.2 -1.0
Blood Platelet Count 0.3 3.1 10.5 0.1 0.9 0.9 -0.7 0.7 0.0 3.2 -1.4 0.7 1.8 1.1 1.0 1.9 1.2 2.4 -0.7 3.2 -0.5 3.1 1.8 3.1
Blood Red Count 0.1 0.8 4.0 -0.2 -0.3 -0.8 -0.9 -0.5 0.0 0.7 1.1 0.0 1.9 -0.2 -1.3 -0.4 0.3 0.6 -1.3 0.6 0.8 1.0 2.0 0.4
Blood White Count 1.8 13.0 30.5 -3.2 3.2 4.4 3.0 5.0 0.0 4.0 1.6 4.5 2.5 4.4 4.7 5.5 3.7 3.9 2.8 2.8 -3.6 0.6 -0.8 5.0
Heel T-Score 19.7 156.8 302.8 -15.7 8.1 17.3 16.7 9.4 0.0 6.9 8.7 17.4 10.8 14.3 13.2 17.3 13.3 14.2 13.9 0.3 -13.8 -10.8 -10.9 9.8
BMI 0.4 2.2 11.4 0.9 2.9 -0.2 1.1 2.6 0.0 0.9 -0.3 -0.0 3.4 -1.1 -0.1 0.3 0.9 1.8 -0.2 2.9 0.8 1.3 0.8 0.3
Height 4.0 77.0 187.7 9.8 -5.8 -12.2 -7.7 -7.4 0.0 -9.5 -5.2 -12.1 2.6 -12.0 -13.7 -12.7 -8.1 -8.6 -5.2 -4.0 9.7 5.0 8.3 -9.7
Waist Hip Ratio (WHR) 2.7 12.2 32.9 -3.2 4.0 3.8 3.5 3.4 0.0 2.3 3.8 5.7 -4.5 3.3 4.8 2.9 2.1 2.6 4.6 1.6 -2.7 -3.3 -4.6 1.1
Systolic Blood Pressure 0.2 0.9 7.3 0.2 -2.7 1.1 -0.9 -0.4 0.0 -0.1 -0.3 1.3 -0.8 0.2 0.3 0.8 0.8 1.1 -0.1 -0.7 1.0 0.0 -1.4 0.0
Smoking Status 0.4 0.9 2.6 -1.2 0.9 0.1 0.3 1.1 0.0 1.2 -1.6 0.5 0.4 1.6 1.2 0.1 -0.4 -0.3 0.7 0.7 -1.6 -0.9 -1.4 0.7
Allergy or Eczema 0.4 1.0 3.3 0.6 0.7 -1.0 -1.2 0.3 0.0 1.5 0.2 -0.4 1.6 -0.4 -1.1 -0.4 -0.1 0.4 0.2 1.7 1.1 1.5 1.8 1.4
Cardiovascular Disease 0.1 0.5 2.7 0.7 -0.5 0.0 0.3 1.6 0.0 -0.7 0.8 0.5 -0.9 -0.7 -0.3 -0.0 0.4 0.7 -0.2 0.4 1.4 0.2 -0.9 -0.7
Hypothyroidism (self reported) 2.1 4.9 10.4 2.5 -2.4 -2.9 -1.9 -1.5 0.0 -2.6 0.5 -2.7 -1.7 -2.5 -2.6 -3.2 -2.2 -3.0 -1.2 -1.8 2.6 0.8 1.6 -2.9
Respiratory disease 2.1 4.8 12.4 2.5 -0.0 -3.5 -2.8 1.1 0.0 0.1 -1.0 -3.3 1.1 -2.0 -2.8 -2.8 -3.0 -2.0 -1.6 1.8 2.5 2.8 2.5 -0.0
Type 2 Diabetes (T2D) (2018) 1.2 2.2 6.1 -1.5 -0.8 1.9 1.5 1.3 0.0 0.3 1.5 2.4 -0.7 1.5 2.1 1.7 1.4 1.2 2.2 -0.7 -1.0 -0.4 -2.5 1.1
Lung FEV1/FVC ratio 0.2 1.2 6.6 1.5 0.7 -0.7 0.2 -0.4 0.0 -1.5 -0.2 -0.5 0.4 -2.4 -0.6 -1.1 -0.2 -0.0 -0.8 -0.3 1.7 -0.6 0.5 -2.6
Lung FVC 0.3 1.6 4.6 1.2 1.1 -1.5 0.3 0.1 0.0 -1.0 -1.3 -1.3 2.1 -1.7 -1.9 -1.6 -1.2 -1.8 -1.1 0.7 1.5 0.7 0.2 -1.4
Neuroticism 0.3 0.8 2.7 1.6 0.1 -0.7 -0.4 1.0 0.0 -0.1 1.1 -0.1 -0.7 -1.3 -0.1 -0.9 -0.1 0.3 -1.4 0.5 1.5 0.9 0.7 -1.4
Chronotype (morning person) 0.4 0.9 4.5 -0.4 0.9 0.6 2.1 -0.2 0.0 -1.2 1.5 0.6 -1.7 0.2 0.5 0.1 0.6 0.4 1.2 -0.7 -0.4 -1.3 -1.0 -0.8
Hair Pigment 19.1 543.3 1459.2 -9.6 21.3 23.8 7.8 28.6 0.0 35.0 -4.4 19.1 32.8 19.5 20.0 36.6 19.6 32.1 9.4 33.2 -13.5 18.2 5.9 38.2
Tanning 3.6 44.0 123.2 0.2 -4.9 -5.8 -0.6 -8.0 0.0 -10.1 3.5 -3.5 -10.3 -3.9 -3.6 -10.1 -5.8 -9.5 -1.5 -10.5 2.1 -7.7 -4.2 -11.1
Hand grip strength (left) 0.5 1.4 5.2 1.0 0.3 -0.9 -0.0 -1.5 0.0 -2.0 -1.0 -0.4 1.4 -1.8 -1.6 -1.0 0.5 -0.8 -0.5 -0.9 0.9 -0.2 1.8 -2.3
Number of treatments/medications taken 0.6 1.0 4.4 -0.1 0.6 -0.0 -0.8 1.6 0.0 2.1 0.4 -0.0 0.2 0.6 0.1 0.5 -1.2 0.7 0.2 2.1 0.7 1.8 0.5 1.7
Average weekly spirits intake 0.9 1.1 5.0 -0.5 1.6 0.1 -0.2 1.8 0.0 2.2 -0.1 0.2 1.2 0.5 1.0 0.4 1.1 0.2 0.8 1.9 -0.2 0.6 -1.1 1.4
Sensitivity / hurt feelings 0.7 1.1 4.7 -0.5 1.9 0.9 1.4 2.2 0.0 0.9 1.8 1.4 0.5 0.5 0.9 0.6 1.4 0.4 0.8 0.1 -0.9 -0.9 -0.4 -0.5
Frequency of depressed mood in last 2 weeks 0.4 0.6 2.0 -0.2 -0.3 1.0 1.0 0.2 0.0 -0.5 1.4 0.9 -0.3 0.2 1.3 0.7 0.7 0.8 -0.1 -1.2 -0.2 -0.7 -1.2 -0.3
Hearing difficulty/problems: Yes 0.8 1.3 3.7 -1.4 -1.1 1.6 0.7 0.3 0.0 0.2 0.7 1.2 0.9 1.6 1.0 1.6 0.1 1.2 1.4 -1.9 -1.3 -0.8 0.6 1.3
Relative age of first facial hair 1.0 2.2 6.4 -0.4 0.6 1.6 -0.2 1.1 0.0 2.5 -0.5 1.1 1.8 1.1 1.8 2.4 1.2 2.2 0.2 1.4 -0.9 1.7 1.5 2.4
Other serious medical condition/disability diagnosed by doctor 0.7 0.8 2.7 1.4 0.5 -0.8 -0.8 1.0 0.0 0.4 0.3 -1.1 -0.5 -1.2 -0.0 -0.7 -1.0 -0.6 -1.2 0.7 1.7 1.4 1.1 -0.6
Ever used hormone-replacement therapy (HRT) 0.9 1.1 4.5 1.1 0.2 -0.7 -1.4 -0.5 0.0 0.2 -2.0 -0.9 1.5 -0.6 -0.9 0.0 -0.7 -0.1 -0.7 1.2 0.8 1.8 2.1 0.8
Ever had hysterectomy (womb removed) 0.3 0.3 2.5 -0.1 0.2 0.1 0.5 1.6 0.0 0.1 0.2 0.4 0.3 0.5 0.5 0.5 0.1 0.7 1.0 0.4 -0.0 0.6 -0.2 0.6
Systolic blood pressure, automated reading 0.2 0.6 3.8 0.7 -2.0 0.2 -0.9 0.2 0.0 0.6 -0.2 0.2 -0.5 -0.3 -0.6 0.1 -0.0 1.2 -0.1 0.2 1.7 0.6 -0.9 0.2
Eye problems/disorders: Diabetes related eye disease 1.8 2.0 4.9 -1.0 1.8 1.2 1.5 2.2 0.0 2.0 0.8 1.4 -1.6 1.1 2.1 1.1 0.7 1.8 1.1 1.9 -1.0 -0.5 -1.5 0.9
Angina 2.2 2.9 6.6 -2.2 -0.1 2.3 0.9 0.0 0.0 1.6 -0.4 1.8 -0.5 2.6 2.1 2.4 1.9 2.4 1.7 -0.1 -2.1 -1.4 -1.5 2.3
Medication for hormone replacement therapy 0.6 0.7 2.2 1.0 -0.4 1.4 0.1 -0.5 0.0 -0.7 -0.3 0.4 -0.5 -1.0 0.5 1.4 1.1 1.5 -0.3 -0.3 1.2 -0.1 0.5 -1.2
Vitamin and mineral supplements 0.2 0.2 0.9 0.2 0.7 0.3 0.6 0.7 0.0 0.1 0.2 0.5 -0.3 -0.2 0.9 0.0 0.8 0.5 0.3 0.5 -0.0 -0.1 -0.8 -0.7
Supplements: Zinc 0.2 0.3 1.3 -0.1 0.6 0.2 0.2 -0.5 0.0 -0.1 0.3 -0.3 1.2 0.3 0.1 0.5 -0.2 1.1 -0.2 0.0 0.1 -0.3 1.1 0.5
Medication: Co-codamol 0.3 0.4 2.9 -0.1 -0.2 0.6 0.5 1.0 0.0 0.7 1.7 0.6 -1.0 -0.2 0.6 0.5 -0.5 -0.2 0.6 -0.0 -0.0 0.1 -0.1 -0.4
Medication: Metformin 1.9 2.7 7.2 -1.8 0.7 2.0 1.9 2.0 0.0 0.5 0.8 2.2 -0.1 2.1 2.2 1.9 1.1 1.4 2.7 -0.5 -1.7 -0.8 -2.4 1.5
Diabetes (father) 1.4 1.7 4.5 -0.9 2.1 1.4 1.9 2.0 0.0 -0.0 1.6 1.3 -1.2 0.4 1.2 1.3 1.6 1.1 1.7 -0.1 -1.1 -1.6 -1.4 -0.3
Diabetes (mother) 0.3 0.4 2.0 -0.3 -1.0 0.6 0.1 0.2 0.0 0.1 1.1 0.4 -1.4 0.2 0.0 0.2 1.2 0.5 0.5 -0.5 0.1 -0.3 -1.1 -0.1
Severe depression (siblings) 0.5 0.5 2.3 -0.2 1.3 0.0 -0.3 1.5 0.0 1.5 -0.1 0.2 1.1 0.6 0.8 0.2 -0.0 -0.5 0.5 0.6 -0.9 0.5 -0.2 0.9
Pack years adult smoking proportion 0.1 0.1 0.4 0.3 -0.5 -0.0 -0.2 -0.1 0.0 -0.1 -0.6 -0.1 -0.0 0.0 0.5 0.2 -0.5 0.0 -0.0 0.2 -0.3 -0.1 -0.3 0.7
Impedance of leg (right) 1.3 6.3 23.4 2.2 -3.9 -2.5 -4.5 -2.2 0.0 -0.2 -0.5 -2.5 -4.8 -1.4 -1.8 -2.5 -3.0 -3.7 -2.8 -0.3 1.9 2.0 0.2 -0.7
Leg fat-free mass (left) 1.1 5.9 21.7 2.3 1.0 -3.1 0.1 -0.6 0.0 -3.4 -1.7 -2.9 4.7 -3.6 -3.9 -3.0 -1.3 -1.2 -0.6 -0.6 2.2 0.8 2.9 -2.7
Trunk fat percentage 1.0 4.2 9.9 2.7 0.6 -3.1 -2.0 0.2 0.0 -0.9 -0.5 -3.1 0.3 -2.8 -2.6 -2.9 -2.5 -1.5 -2.1 2.5 3.0 1.9 1.0 -1.0
Hand grip strength (right) 0.4 1.0 4.3 0.5 -0.2 -0.8 0.3 -1.1 0.0 -2.1 -0.4 -0.2 0.9 -1.3 -1.3 -0.9 1.2 -1.2 0.4 -1.5 0.3 -0.6 0.9 -1.8
Townsend deprivation index at recruitment 0.2 0.3 1.3 -0.1 -1.1 0.5 -0.3 0.6 0.0 0.3 -0.2 0.3 0.1 0.6 0.4 0.6 -0.5 -0.8 0.4 0.2 0.0 1.0 0.0 0.8
Current tobacco smoking 1.7 2.9 7.8 -2.3 1.4 1.7 2.1 1.3 0.0 1.3 0.0 2.0 -0.3 2.6 2.4 1.5 0.6 0.4 1.8 1.0 -2.8 -1.8 -2.4 1.3
Average weekly fortified wine intake 0.2 0.2 1.1 -0.3 -0.3 0.3 0.5 -1.1 0.0 -0.6 0.4 0.4 -0.5 0.0 0.2 0.1 -0.0 -0.3 0.3 -0.7 0.3 -0.5 -0.3 -0.4
Maternal smoking around birth 0.2 0.3 2.5 -0.2 -0.6 -0.3 0.2 -0.2 0.0 -0.4 -0.3 -0.1 1.6 0.2 -0.5 -0.2 -0.7 -0.7 1.2 0.1 0.4 -0.1 -0.5 0.4
Fed-up feelings 0.2 0.3 1.0 0.5 0.3 0.6 -0.0 0.6 0.0 0.7 0.6 0.5 0.4 0.1 0.4 0.8 0.4 1.0 -0.2 0.7 0.5 0.8 0.3 0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 1.5 2.0 4.8 -1.0 2.2 1.7 1.8 1.1 0.0 0.6 0.6 1.7 -0.3 1.5 1.8 1.7 1.5 1.6 1.5 0.9 -1.5 -1.4 -2.1 1.1
Relative age voice broke 0.6 0.9 2.5 1.2 -1.4 -1.1 -0.9 -0.8 0.0 -0.7 -0.9 -1.1 0.9 -1.1 -1.6 -1.0 0.2 -0.3 -0.2 -0.8 0.7 1.0 1.6 -0.4
Taking other prescription medications 0.9 1.3 6.0 0.6 0.7 -0.4 -1.6 1.1 0.0 2.3 -0.8 -0.4 0.7 0.3 0.7 0.2 -1.3 0.1 -0.3 2.4 0.5 2.0 1.0 1.8
Age when periods started (menarche) 0.1 0.3 2.1 -0.0 0.1 0.1 0.0 -0.8 0.0 0.2 -0.6 0.0 -1.4 -0.2 0.3 0.2 1.0 1.1 -0.1 0.4 -0.4 -0.9 0.3 -0.1
Bilateral oophorectomy (both ovaries removed) 1.9 2.1 5.8 -1.1 2.4 1.5 1.3 1.5 0.0 1.3 -0.3 1.7 0.8 1.5 1.9 2.0 0.7 2.0 1.6 2.0 -1.2 -0.7 -0.3 1.8
Heel bone mineral density (BMD) T-score, automated (left) 9.4 21.3 42.4 -5.4 3.3 6.2 6.3 4.3 0.0 2.3 3.4 6.2 5.3 4.9 4.5 6.5 5.1 5.5 4.8 0.2 -4.8 -3.1 -3.2 4.1
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 1.8 -0.2 -0.8 0.6 0.4 1.2 0.0 -0.1 1.3 0.7 -0.0 -0.0 0.0 0.6 1.3 0.7 0.2 -0.6 0.0 0.6 -0.3 -0.2
Qualifications: CSEs or equivalent 1.0 1.3 4.7 -1.3 -1.2 1.7 0.4 0.8 0.0 0.9 0.6 1.8 -0.2 1.1 1.3 1.7 2.2 1.2 0.9 -0.7 -1.4 0.1 -0.3 0.9
Serious illness, injury or assault to yourself 1.5 1.8 7.0 1.5 1.1 -0.8 -1.7 1.4 0.0 1.4 -1.1 -1.0 1.8 -1.0 0.7 -0.4 -1.9 -0.1 -0.9 2.0 1.6 2.6 1.5 0.4
High blood pressure 0.2 0.5 1.2 -0.4 -0.8 0.6 0.5 1.0 0.0 0.2 0.3 0.9 -0.0 0.5 0.4 0.9 1.1 1.0 1.1 0.5 0.2 0.3 -0.9 1.1
Hayfever, allergic rhinitis or eczema 1.1 2.5 7.0 1.9 -0.5 -2.3 -1.8 -0.4 0.0 -0.6 -0.4 -1.7 1.7 -2.1 -2.6 -1.8 -0.9 -0.7 -1.3 0.5 2.2 1.9 2.6 -0.3
Multivitamins +/- minerals 1.1 1.3 4.6 -1.5 1.5 1.3 1.1 0.3 0.0 1.5 -0.6 1.1 1.0 1.7 0.5 1.6 0.1 1.2 1.0 0.7 -1.4 -0.9 -0.0 2.1
Stomach or abdominal pain in last month 2.4 2.9 5.8 -2.0 0.6 2.1 2.3 0.9 0.0 1.0 2.0 2.2 -0.9 1.7 2.4 1.7 2.3 2.0 1.3 -0.8 -2.4 -1.9 -1.6 0.9
Supplements: Glucosamine 0.3 0.4 1.9 -0.3 0.3 0.7 0.3 1.0 0.0 1.0 -0.3 0.5 0.6 0.6 0.4 0.8 -0.8 0.5 1.4 0.4 -0.6 -0.3 0.0 0.6
Diverticular disease/diverticulitis (self-reported) 2.2 2.6 6.8 -1.7 0.6 1.8 0.8 0.9 0.0 1.5 -1.0 1.7 1.9 2.6 2.5 2.2 0.3 1.2 1.7 0.4 -2.4 -0.5 -1.4 2.6
Medication: Atenolol 2.0 2.5 5.2 -2.3 0.9 2.2 1.6 1.1 0.0 0.7 1.0 2.3 -0.1 2.1 1.6 2.2 1.5 2.1 1.8 0.8 -1.4 -1.6 -1.7 1.5
Medication: Levothyroxine sodium 0.3 0.5 2.6 0.1 -1.0 -0.8 -0.3 0.3 0.0 -0.7 1.1 -0.6 -1.1 0.1 -0.2 -1.0 -1.6 -1.0 0.6 -0.9 0.5 -0.1 0.4 -0.1
Sitting height 1.1 7.7 24.0 2.5 -0.3 -4.0 -1.3 -1.9 0.0 -3.3 -2.4 -4.0 2.6 -3.8 -4.9 -4.2 -1.9 -2.2 -0.8 -1.6 2.3 0.6 3.1 -3.3
Chronic bronchitis/emphysema (father) 0.3 0.4 2.6 0.6 -0.5 -0.5 -0.7 0.2 0.0 0.5 -1.0 -0.6 0.0 0.0 0.5 0.1 -0.1 0.4 -0.3 0.5 0.1 1.6 1.3 0.5
High blood pressure (mother) 0.2 0.2 2.0 -0.1 -0.2 0.4 -0.5 0.2 0.0 -0.1 -0.7 0.3 0.8 0.3 0.2 0.5 -0.3 0.1 -0.3 0.1 -0.4 0.2 -1.4 0.8
Body mass index (BMI) 0.3 1.3 5.5 1.1 2.2 -0.9 0.7 1.9 0.0 -0.2 0.4 -0.7 2.4 -1.4 -0.6 -0.7 0.0 0.8 -0.9 1.9 1.2 1.0 0.8 -0.3
Impedance of leg (left) 1.0 4.8 25.7 1.7 -3.8 -1.8 -3.9 -2.0 0.0 0.4 -0.2 -2.0 -5.1 -0.8 -1.0 -1.9 -2.3 -3.2 -2.2 -0.1 1.6 1.7 -0.5 -0.4
Leg predicted mass (left) 1.1 5.7 22.2 2.2 1.0 -3.1 0.1 -0.6 0.0 -3.3 -1.7 -2.9 4.7 -3.5 -3.9 -3.0 -1.3 -1.1 -0.6 -0.5 2.2 0.8 2.8 -2.5
Trunk fat mass 1.3 5.7 13.5 3.1 0.9 -3.7 -1.7 0.2 0.0 -1.6 -0.8 -3.6 1.4 -3.6 -3.3 -3.4 -2.4 -1.5 -2.2 2.1 3.3 2.1 1.8 -1.7
Waist circumference 0.5 1.7 5.7 1.7 1.3 -1.8 -0.1 1.6 0.0 -0.9 1.2 -1.3 0.3 -2.1 -1.2 -1.8 -0.8 -0.1 -0.6 1.8 2.4 1.1 0.4 -1.0
Number of incorrect matches in round 0.8 1.3 4.8 -0.9 2.2 0.5 1.0 1.7 0.0 2.1 -0.2 0.6 0.5 1.4 0.7 0.7 0.5 1.0 1.4 1.5 -0.6 -0.3 -0.6 1.7
Past tobacco smoking 0.1 0.2 1.9 0.3 -0.1 0.1 0.3 -0.4 0.0 -0.5 1.4 0.2 -1.0 -0.6 0.2 0.2 -0.5 -0.0 -0.1 -0.3 0.7 0.0 0.3 0.1
Alcohol usually taken with meals 4.4 7.1 19.3 3.4 -0.9 -3.7 -2.8 -2.2 0.0 -1.5 -3.8 -4.4 1.7 -3.2 -2.9 -3.4 -3.1 -2.2 -2.5 -0.5 2.4 1.8 3.1 -1.5
Nervous feelings 0.5 0.9 3.5 1.3 0.3 -1.0 -0.5 -0.1 0.0 -0.2 0.8 -0.8 -1.1 -1.4 -0.6 -1.1 -0.6 0.3 -1.5 0.7 1.9 0.5 1.1 -0.8
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.3 1.2 0.8 -0.6 -0.2 -0.6 -0.5 0.0 -0.1 0.5 -0.2 -0.7 -0.6 0.3 -0.2 -0.1 0.4 -1.1 -0.1 0.7 0.7 0.5 -0.3
Hearing difficulty/problems with background noise 0.1 0.2 2.8 0.2 -0.2 -0.3 -0.1 0.5 0.0 0.5 0.4 -0.2 0.8 -0.0 -0.3 -0.4 0.0 0.6 -0.2 -0.3 -0.0 0.3 1.7 0.0
Hair/balding pattern: Pattern 2 2.4 3.0 7.0 -2.0 2.5 1.8 2.5 2.3 0.0 1.2 1.3 2.1 1.6 1.9 1.0 2.1 1.3 1.6 2.0 0.6 -2.6 -0.8 -0.2 2.0
Had menopause 0.4 0.5 1.6 0.6 -0.0 -0.4 -1.2 0.4 0.0 1.0 0.4 -0.4 0.5 -0.4 -0.5 -0.2 0.5 0.6 0.4 1.3 1.2 1.0 0.7 0.1
Had other major operations 0.4 0.4 2.1 -0.3 1.4 -0.1 0.3 1.0 0.0 0.7 1.1 0.2 0.4 0.6 -0.1 0.2 0.3 0.6 -0.1 1.2 -0.1 0.7 0.6 1.0
Forced vital capacity (FVC) 2.5 9.5 28.0 3.2 -1.8 -3.9 -1.9 -2.2 0.0 -4.0 -2.9 -3.8 1.8 -4.2 -5.3 -4.2 -2.6 -4.1 -1.4 -1.9 2.9 1.0 1.5 -4.0
Heel bone mineral density (BMD) T-score, automated (right) 11.9 27.2 55.4 -6.8 3.0 7.0 6.8 3.6 0.0 2.5 3.4 7.4 5.3 6.3 5.4 7.3 5.0 5.4 6.0 -0.4 -6.0 -4.0 -4.3 5.0
Ever unenthusiastic/disinterested for a whole week 0.6 0.8 2.4 1.5 0.5 0.5 -0.3 1.5 0.0 0.2 0.2 -0.0 0.4 -1.2 -0.2 0.8 -0.0 1.6 -0.9 1.4 1.2 0.4 1.2 -0.5
Qualifications: None of the above 1.1 2.3 7.5 -1.6 1.5 1.2 0.6 0.8 0.0 2.7 -0.5 1.4 -0.4 2.3 1.3 1.4 0.3 2.1 1.6 2.4 -1.2 -0.3 -1.2 2.4
Financial difficulties in last 2 years 0.6 0.8 3.0 -0.1 0.7 0.7 1.0 1.3 0.0 -0.0 1.7 0.8 -1.3 0.2 1.2 0.4 1.6 0.6 0.4 -0.4 -0.4 -1.3 -1.4 -0.4
Mouth/teeth dental problems 1.2 1.9 6.2 1.0 -2.0 -1.5 -1.0 -1.8 0.0 -2.5 -0.9 -1.0 -0.4 -1.4 -1.4 -1.7 -1.1 -1.9 0.3 -2.0 0.9 -0.6 -0.7 -1.7
Heart attack 0.2 0.2 1.2 -0.4 -1.1 0.1 -0.3 -0.9 0.0 0.2 0.3 -0.1 -0.7 0.2 -0.4 0.2 0.1 0.5 -0.3 -0.6 0.3 -0.3 -0.1 0.4
Allergy 1.6 3.6 9.8 -2.4 0.7 2.8 2.1 -0.8 0.0 0.6 0.3 2.4 -2.0 2.2 2.6 2.1 1.3 1.2 2.0 -0.7 -2.3 -2.8 -3.1 0.2
Pain all over the body in last month 0.8 0.8 3.4 1.6 0.1 -0.7 -0.8 0.6 0.0 1.1 -0.9 -0.9 0.6 -1.3 0.0 -0.4 -0.4 -0.1 -1.1 0.9 1.2 1.8 1.2 -0.2
Diabetes (self-reported) 1.4 2.1 6.5 -1.6 -0.4 1.9 1.3 1.4 0.0 0.7 0.8 2.0 -0.7 1.9 2.6 1.8 0.6 0.4 2.3 -0.8 -1.7 -0.3 -2.0 1.5
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 2.8 0.7 -1.1 -0.4 -1.1 -0.1 0.0 -0.3 -0.4 -0.4 -0.3 -0.9 -0.6 -0.3 0.8 0.8 -0.1 0.2 1.7 0.6 0.3 -0.3
Medication: Ramipril 0.9 1.2 3.0 -1.3 0.5 1.3 0.7 1.3 0.0 1.7 0.5 1.2 -0.1 1.4 1.2 1.7 0.8 0.9 1.3 0.6 -0.7 0.3 -1.3 1.6
Medication: Simvastatin 0.5 0.7 2.7 0.4 -0.2 0.3 0.8 1.0 0.0 -0.9 1.7 0.1 -1.5 -0.4 1.1 0.1 0.8 1.2 1.2 -1.2 0.3 -0.5 -0.1 -0.8
Fluid intelligence score 1.3 2.6 6.8 1.9 -0.7 -2.1 -2.3 -0.4 0.0 0.1 -1.9 -2.1 2.4 -1.5 -0.7 -1.7 -1.4 -2.0 -1.8 0.6 1.4 2.6 1.9 -0.2
Illnesses of siblings 0.7 0.9 4.2 0.8 0.9 -0.9 -0.2 -0.6 0.0 -1.0 -1.4 -0.8 -0.6 -1.2 -1.2 -0.9 0.4 -0.8 -2.0 -0.5 0.2 -0.3 1.3 -1.5
Neuroticism score 0.2 0.5 1.6 0.6 0.1 0.5 -0.1 1.0 0.0 1.0 1.2 0.6 -0.4 -0.4 0.7 0.4 1.0 1.3 -0.6 0.8 0.5 0.6 0.3 -0.4
Weight 1.4 7.1 17.6 3.2 0.6 -3.9 -1.0 -0.3 0.0 -2.8 -1.2 -3.7 3.2 -4.2 -4.1 -3.8 -2.0 -1.5 -1.9 0.5 3.2 1.8 2.7 -2.7
Impedance of arm (right) 1.0 4.5 11.7 1.8 -2.5 -2.6 -3.2 -2.2 0.0 -0.7 -1.2 -2.8 -3.4 -1.5 -2.1 -2.7 -3.0 -3.2 -1.4 -0.1 1.9 0.5 0.3 -0.9
Arm fat percentage (right) 0.5 2.0 5.2 1.9 1.2 -2.0 -0.8 0.9 0.0 -0.5 -0.1 -2.1 0.7 -2.1 -1.5 -1.8 -1.4 -0.3 -1.6 2.1 2.3 1.4 0.8 -0.5
Trunk fat-free mass 1.3 7.5 20.7 2.7 0.1 -3.7 -0.5 -0.6 0.0 -3.2 -1.6 -3.4 4.5 -4.2 -4.4 -3.7 -1.6 -1.6 -1.1 -1.2 2.6 1.8 3.4 -3.2
Hip circumference 2.5 10.6 25.4 4.2 -1.2 -4.9 -2.5 -0.6 0.0 -3.1 -0.7 -5.0 1.9 -4.8 -4.7 -4.6 -2.6 -2.4 -3.3 0.4 4.5 2.7 3.4 -2.7
Time employed in main current job 0.2 0.2 0.8 0.2 -0.0 -0.3 -0.7 -0.5 0.0 0.4 -0.2 -0.6 0.1 -0.0 -0.4 -0.1 -0.9 0.0 0.3 0.3 0.2 0.7 0.6 0.7
Alcohol intake versus 10 years previously 0.7 1.0 4.1 -1.1 0.4 1.0 0.4 0.3 0.0 1.2 -0.3 0.9 -0.6 1.7 2.0 1.0 0.7 0.9 0.8 0.9 -1.2 -0.7 -1.3 1.6
Father’s age at death 0.5 0.7 2.6 0.6 1.1 -0.6 0.6 1.6 0.0 0.5 1.5 -0.4 -0.0 -0.8 -0.4 -0.6 0.1 1.2 -0.1 1.0 0.9 0.7 1.6 0.0
Worrier / anxious feelings 0.2 0.4 1.7 0.9 -0.4 0.2 -0.8 0.0 0.0 0.3 0.1 -0.0 -0.4 -0.5 0.6 0.2 0.1 1.3 -1.3 -0.4 0.3 0.2 1.2 -0.2
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.4 1.7 -0.2 -1.3 0.8 -0.2 -0.6 0.0 0.4 -0.2 0.6 0.0 0.4 1.2 0.8 0.8 0.6 -0.3 -0.9 -0.2 0.6 0.4 0.3
Falls in the last year 0.3 0.3 1.8 0.2 1.2 0.2 0.4 1.4 0.0 0.7 0.2 -0.0 -0.1 0.2 1.1 0.3 0.2 0.4 -0.3 1.1 -0.4 0.0 -0.3 0.3
Hair/balding pattern: Pattern 3 0.3 0.5 2.2 -0.4 -0.1 0.6 0.4 -0.1 0.0 -0.1 1.1 0.6 -1.4 -0.0 1.1 0.2 1.5 0.3 0.3 -0.4 0.8 -0.8 -0.8 -0.8
Number of live births 1.1 1.6 6.2 -1.0 0.3 2.0 0.6 1.9 0.0 1.6 0.2 1.4 1.3 1.6 1.2 2.5 0.7 0.8 0.4 0.8 -1.1 0.9 -0.9 1.8
Forced expiratory volume in 1-second (FEV1) 2.9 9.8 24.5 3.4 -1.6 -3.7 -1.8 -2.2 0.0 -4.7 -2.2 -3.5 1.8 -4.7 -5.0 -4.2 -2.1 -4.1 -1.7 -2.3 3.2 0.7 1.4 -4.7
Pulse rate 0.7 1.2 7.3 -0.4 -0.7 0.5 1.4 -0.8 0.0 -2.7 1.1 1.0 -0.3 -0.0 -0.2 0.1 1.1 0.4 0.1 -2.2 -0.7 -2.0 -0.5 -1.3
Happiness 0.9 1.1 5.8 1.6 -0.1 -0.1 0.6 1.5 0.0 -1.3 1.5 0.1 -0.4 -1.8 -0.3 -0.4 1.4 -0.4 -1.2 -0.2 0.8 -0.2 0.3 -2.4
Noisy workplace 0.8 0.9 4.4 1.5 -0.4 -0.5 -0.4 1.1 0.0 -0.5 0.2 -0.5 -2.1 -1.4 -0.5 -0.6 -0.6 0.5 -1.5 0.7 1.5 1.1 0.1 -1.1
Qualifications: A levels/AS levels or equivalent 0.4 0.9 5.6 1.4 0.5 -1.0 -1.0 -0.2 0.0 -0.4 -2.4 -1.1 1.5 -1.2 -0.4 -0.8 -0.4 -0.9 -0.4 0.2 0.2 1.1 0.9 -0.7
Serious illness, injury or assault of a close relative in last 2 years 1.2 1.4 3.2 -1.5 -0.3 1.4 1.6 -0.1 0.0 0.5 0.1 1.1 0.5 1.5 1.3 1.3 1.5 1.3 1.4 -0.9 -1.8 -1.4 -0.7 1.3
Mouth/teeth dental problems: Dentures 0.9 1.6 5.2 -1.1 1.7 0.8 0.8 1.3 0.0 2.1 -0.5 0.3 0.5 1.9 0.8 1.2 0.2 1.6 -0.1 2.1 -1.5 -0.0 -0.7 2.3
Asthma 2.7 5.3 11.9 3.1 -0.9 -3.3 -3.1 1.0 0.0 -0.5 -1.3 -3.3 1.2 -2.3 -2.6 -2.5 -2.4 -1.9 -2.7 1.5 2.5 3.5 3.2 -0.2
Medication: Ibuprofen (e.g. Nurofen) 2.4 3.1 7.3 -2.1 1.3 2.1 2.2 1.5 0.0 0.8 2.3 2.4 -1.0 2.2 2.7 2.0 1.0 0.8 2.3 -0.3 -2.4 -1.5 -1.3 1.0
Medication: Cholesterol lowering 0.3 0.5 1.9 -0.2 0.3 0.8 0.5 1.2 0.0 0.8 1.0 0.7 -1.1 0.4 1.2 0.8 1.1 1.4 0.0 -0.1 -0.1 0.2 0.0 0.2
Depression (self-reported) 0.8 0.9 2.3 -0.3 0.6 0.6 0.6 1.5 0.0 1.5 0.3 0.5 1.5 0.5 1.5 1.0 1.3 1.0 0.2 1.3 -0.8 0.8 0.8 1.3
Medication: Lansoprazole 0.6 0.7 3.2 -0.4 1.2 0.1 0.1 1.4 0.0 1.8 -0.8 -0.2 0.9 1.0 0.3 0.3 -0.2 0.5 0.5 1.2 -0.8 0.6 0.0 1.5
Prospective memory result 0.3 0.4 1.6 -0.7 0.1 0.6 -0.4 -0.5 0.0 0.4 0.1 0.9 -1.0 0.7 1.0 0.6 -1.3 -0.1 0.0 0.4 -0.4 -0.1 -1.0 0.4
Lung cancer (father) 0.5 0.6 2.9 -0.8 0.4 0.9 1.7 -0.1 0.0 0.6 0.9 1.0 0.3 0.7 0.8 0.9 0.3 1.4 0.8 -0.4 -0.6 -0.9 -0.5 0.4
Illnesses of mother 0.4 0.4 2.3 0.1 1.0 -0.7 0.7 -0.7 0.0 -0.4 -0.1 -0.5 -0.0 -0.4 -0.5 -0.9 -0.6 -0.5 0.2 -0.2 -0.3 -1.0 1.5 -1.0
Forced expiratory volume in 1-second (FEV1), Best measure 1.6 5.0 13.1 2.0 -0.6 -2.7 -1.2 -1.8 0.0 -3.2 -1.8 -2.4 2.2 -3.2 -3.3 -2.9 -1.9 -3.6 -1.0 -1.5 2.1 0.3 1.0 -3.3
Pulse wave Arterial Stiffness index 1.3 1.5 3.3 1.7 -1.0 -1.7 -1.4 -0.3 0.0 -0.5 -1.2 -1.5 -0.3 -1.3 -1.7 -1.8 -1.8 -1.6 -1.5 0.7 0.6 1.0 0.1 -1.0
Impedance of arm (left) 0.4 2.0 10.3 0.5 -2.2 -1.2 -2.2 -2.0 0.0 -0.4 -0.5 -1.5 -3.2 -0.2 -0.9 -1.3 -2.2 -2.2 -0.6 -0.1 0.5 -0.5 -0.7 0.1
Arm fat mass (right) 0.8 3.4 8.3 2.3 1.4 -2.7 -0.7 0.7 0.0 -1.4 -0.4 -2.6 2.0 -2.9 -2.6 -2.5 -1.5 -0.6 -1.6 1.5 2.6 1.5 1.6 -1.4
Trunk predicted mass 1.3 7.4 20.4 2.7 0.2 -3.6 -0.5 -0.6 0.0 -3.1 -1.6 -3.4 4.5 -4.2 -4.3 -3.7 -1.6 -1.6 -1.1 -1.2 2.7 1.8 3.4 -3.2
Standing height 2.5 24.6 64.5 4.9 -3.3 -6.9 -3.6 -4.7 0.0 -6.0 -3.5 -6.9 2.1 -6.6 -8.0 -7.2 -4.5 -5.3 -2.2 -3.3 4.5 1.9 4.5 -5.6
Length of working week for main job 0.3 0.3 1.6 -0.2 0.7 0.4 0.1 -1.2 0.0 -0.0 -1.3 0.1 -0.2 0.1 -0.2 0.5 0.6 0.3 -0.1 0.7 -0.8 -0.5 -0.2 0.1
Exposure to tobacco smoke at home 0.5 0.5 2.0 -0.1 0.2 0.4 0.2 1.2 0.0 1.0 0.9 0.8 -0.7 0.2 0.5 0.8 -0.1 1.4 0.0 1.3 0.4 0.9 -0.6 0.7
Breastfed as a baby 1.3 1.6 4.4 2.1 -0.2 -1.4 -1.8 -1.0 0.0 -0.8 -1.0 -1.4 1.2 -1.6 -1.0 -1.1 -1.3 -1.1 -1.5 -0.1 1.2 1.0 2.0 -0.7
Tense / ‘highly strung’ 0.8 1.4 5.1 -0.9 1.0 1.2 0.4 1.9 0.0 2.3 0.9 1.2 -0.1 1.2 1.1 1.3 1.8 1.9 0.1 0.9 -0.9 -0.0 0.2 1.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 3.6 0.6 0.9 0.7 1.6 1.9 0.0 -0.5 1.1 0.4 0.5 -0.5 0.4 0.7 0.8 1.9 0.0 -0.4 -0.2 -0.5 0.3 -0.8
Hair/balding pattern: Pattern 4 0.3 0.7 3.1 0.5 0.8 -0.7 1.2 0.4 0.0 -1.6 -0.3 0.5 -0.9 -0.8 -0.4 -1.1 -0.1 -0.4 0.7 -0.7 0.6 -0.4 -1.1 -1.8
Birth weight of first child 0.6 1.1 3.4 0.1 -0.8 -1.1 -1.2 -1.4 0.0 -0.5 0.5 -1.2 1.5 -0.8 -1.6 -1.3 -1.8 -1.6 -0.3 -0.9 0.7 0.7 1.0 -0.7
Peak expiratory flow (PEF) 4.1 9.5 23.5 3.8 -2.5 -3.5 -1.7 -1.2 0.0 -4.3 -0.6 -3.1 1.1 -4.8 -4.2 -4.0 -1.9 -4.0 -2.7 -2.5 3.6 1.5 2.0 -4.8
Pulse wave reflection index 0.9 1.1 4.7 1.2 0.6 -1.0 -1.1 0.9 0.0 1.5 -1.3 -1.0 0.3 -0.9 -0.7 -0.8 -0.5 -0.5 -1.3 2.2 0.6 1.8 1.1 0.1
Ever highly irritable/argumentative for 2 days 1.1 1.3 5.7 -0.3 1.4 1.3 1.3 2.4 0.0 1.0 1.4 1.7 1.1 0.3 1.7 1.4 0.5 1.4 0.6 0.8 -0.5 -0.5 -0.2 0.1
Loud music exposure frequency 0.4 0.4 1.6 -0.5 0.4 0.6 0.5 0.7 0.0 -0.1 -0.4 1.2 0.5 0.7 1.1 0.8 -0.2 0.4 -0.0 0.1 -1.3 -0.7 -0.8 0.8
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 1.7 -1.0 0.0 0.8 0.3 0.3 0.0 -0.3 0.6 0.8 -0.7 0.7 1.3 0.5 1.2 -0.6 0.5 -0.6 -1.3 -0.9 -1.1 -0.4
Mouth/teeth dental problems: Bleeding gums 0.6 0.7 2.2 0.9 -1.3 -0.2 -1.5 -1.2 0.0 -0.9 -0.9 -0.7 -0.0 -0.8 -0.7 -0.2 -0.9 -0.1 -1.2 -0.7 1.1 0.5 1.2 -0.5
Blood clot in the leg (DVT) 0.1 0.2 0.7 0.4 -0.6 0.1 0.2 -0.1 0.0 -0.6 0.6 -0.2 -0.3 -0.5 -0.8 0.1 -0.3 0.0 -0.2 -0.6 0.6 -0.1 0.5 -0.6
Medication: Paracetamol 0.1 0.2 1.5 -0.1 0.1 0.3 0.1 0.2 0.0 0.3 0.2 0.4 -0.9 0.3 0.4 0.2 -1.1 0.1 -0.6 0.6 0.0 -0.1 -1.2 -0.0
Headache pain in last month 0.2 0.3 1.5 0.6 -0.8 0.0 0.7 0.5 0.0 -0.4 0.3 -0.2 -1.2 -0.2 0.3 -0.2 0.7 -0.4 -0.9 -0.9 0.1 -0.0 -0.3 -0.4
Medication for cholesterol, blood pressure or diabetes 0.2 0.4 3.4 -0.1 -0.6 -0.2 -0.1 -1.8 0.0 -0.7 -0.8 -0.3 0.5 0.0 -0.4 -0.2 -0.6 -0.8 0.1 -0.9 -0.8 -0.7 0.3 -0.1
Glaucoma (self-reported) 0.6 0.7 3.7 0.8 0.7 -0.7 0.1 1.4 0.0 0.2 -0.7 -0.9 1.9 -0.4 -0.2 -0.2 -1.1 0.2 -0.8 1.1 0.3 0.7 1.2 0.5
Gout (self-reported) 0.4 0.6 2.5 0.1 0.4 -0.3 -1.0 -0.3 0.0 1.0 -0.5 -0.5 0.9 -0.1 -0.5 0.4 -0.2 0.9 -0.2 1.4 0.4 1.6 1.1 1.2
Hypothyroidism/myxoedema (self-reported) 1.4 2.7 5.9 1.4 -2.3 -2.3 -1.7 -1.5 0.0 -1.6 -0.1 -2.1 -1.2 -1.2 -2.1 -2.4 -1.9 -2.4 -0.5 -1.5 1.8 0.8 1.2 -1.3
Medication: Amlodipine 1.0 1.4 6.6 1.8 -0.8 -0.8 -0.9 0.3 0.0 -0.4 0.6 -0.9 -0.6 -2.2 -1.8 -0.7 0.2 0.2 -1.0 0.7 2.6 1.4 1.2 -1.5
Medication: Ventolin 100micrograms inhaler 2.1 2.7 6.4 2.1 -1.4 -2.5 -2.1 -1.0 0.0 -1.6 -0.4 -2.5 0.4 -2.2 -2.1 -2.3 -0.9 -1.0 -1.8 -0.7 1.7 1.3 1.8 -1.3
Birth weight 0.5 1.1 2.9 0.9 0.4 -1.6 -0.7 -0.2 0.0 0.1 -0.9 -1.3 1.7 -1.3 -1.6 -1.6 -0.9 -0.7 -0.8 0.2 1.0 0.9 1.5 -0.8
Chronic bronchitis/emphysema (mother) 0.2 0.3 1.8 0.2 -1.0 -0.1 -0.4 -0.1 0.0 -0.3 -0.4 -0.1 1.0 0.0 0.1 0.3 0.1 0.0 0.3 0.1 0.9 1.3 0.7 0.3
High blood pressure (siblings) 0.4 0.6 3.3 -0.5 -0.8 0.6 -0.2 0.8 0.0 0.7 1.8 0.9 -0.1 0.5 1.0 0.4 -0.6 0.5 1.3 0.1 0.4 0.3 -0.9 0.6
Forced vital capacity (FVC), Best measure 1.5 5.6 14.4 1.9 -1.1 -2.9 -1.4 -2.2 0.0 -3.3 -2.3 -2.8 1.8 -3.1 -3.7 -3.1 -2.1 -3.8 -0.9 -1.6 1.8 0.2 1.1 -3.1
Body fat percentage 0.9 3.5 8.0 2.6 0.7 -2.7 -1.9 0.8 0.0 -0.3 -0.2 -2.8 0.3 -2.5 -1.9 -2.3 -2.0 -1.0 -2.3 2.8 2.8 2.4 1.0 -0.4
Leg fat percentage (right) 0.9 3.2 8.5 2.5 -0.1 -2.2 -2.2 0.7 0.0 0.3 -0.4 -2.3 0.0 -2.1 -1.4 -1.7 -1.6 -0.3 -2.9 2.9 2.5 2.9 1.4 0.2
Arm fat-free mass (right) 1.0 4.9 18.3 2.2 0.8 -2.9 -0.3 -0.1 0.0 -2.4 -1.0 -2.7 4.3 -3.4 -3.5 -2.8 -1.0 -1.1 -1.0 -0.3 2.2 1.8 2.8 -2.4
Exposure to tobacco smoke outside home 1.1 1.5 4.8 -1.8 -0.2 1.4 0.8 -0.1 0.0 -0.5 0.5 1.9 -0.8 1.7 1.5 1.1 0.1 0.1 1.5 -0.4 -1.8 -1.9 -2.2 0.4
Comparative body size at age 10 0.5 1.4 11.1 0.3 2.6 0.3 1.4 0.9 0.0 -1.0 -0.9 0.4 3.3 -0.8 0.4 0.1 0.7 1.2 1.0 0.2 0.5 -1.1 -0.5 -1.3
Number of full brothers 1.4 1.7 5.0 1.7 -0.5 -1.7 -1.6 0.5 0.0 1.1 -0.8 -2.2 0.2 -1.0 -1.1 -1.3 -1.3 -0.9 -1.7 1.2 1.0 2.2 1.9 0.1
Worry too long after embarrassment 0.8 1.4 5.8 1.3 -2.4 -0.5 -1.4 -1.5 0.0 -1.4 0.4 -0.2 -0.6 -1.6 -0.6 -1.0 -0.3 -0.5 -1.3 -1.5 1.4 0.1 0.4 -2.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 2.1 1.5 0.3 -0.9 -0.7 0.6 0.0 -0.6 -0.3 -0.5 0.3 -1.3 -0.5 -0.9 -0.5 -0.4 -0.8 0.4 1.0 0.7 0.3 -1.1
Wheeze or whistling in the chest in last year 1.2 2.1 7.5 2.4 -0.6 -0.9 -2.3 -0.1 0.0 0.3 -1.1 -1.6 -0.2 -1.7 -1.5 -0.2 -0.7 0.4 -1.7 1.5 2.1 2.7 2.1 0.0
Number of children fathered 0.6 0.6 1.9 -0.0 -1.2 -0.9 -0.7 -0.9 0.0 -0.7 0.6 -0.5 0.2 -0.7 -1.4 -1.2 -1.2 -0.9 0.3 -1.1 0.4 -0.2 0.7 -0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 2.3 -0.6 1.3 1.4 1.5 0.4 0.0 -0.3 0.6 1.5 0.6 0.4 -0.1 1.3 0.0 1.5 1.3 -0.5 -0.3 -0.7 -0.9 -0.5
Age at first live birth 0.3 0.6 3.2 0.4 0.3 -0.4 0.2 -0.3 0.0 -0.7 1.4 0.2 -0.2 -1.0 -1.2 -0.6 0.7 -0.8 -0.0 -0.4 0.7 -0.4 1.1 -1.8
Pulse wave peak to peak time 0.7 0.9 2.3 -1.4 0.8 1.2 1.0 -0.1 0.0 0.1 0.9 1.0 0.4 0.9 1.1 1.2 1.5 1.3 1.3 -0.9 -0.3 -0.9 0.3 0.6
Health satisfaction 1.3 1.6 5.2 1.8 -1.8 -0.8 -0.2 -0.9 0.0 -2.3 1.6 -0.8 -0.9 -2.0 -1.0 -0.9 0.2 -0.5 -1.8 -1.3 1.3 0.0 1.0 -1.9
Shortness of breath walking on level ground 0.7 0.8 3.1 0.8 -0.1 -0.9 -1.7 -0.4 0.0 0.4 -1.8 -1.0 1.0 -0.1 -0.5 -0.5 -1.1 -0.9 -1.0 1.0 0.4 1.2 0.7 0.7
Qualifications: College or University degree 2.1 6.7 13.2 3.2 -2.2 -2.9 -2.2 -2.0 0.0 -3.5 -1.6 -3.1 0.7 -3.6 -3.1 -3.2 -2.4 -3.6 -2.2 -2.4 2.8 1.0 1.5 -3.3
Eye problems/disorders: None of the above 0.6 0.7 2.5 0.9 -1.0 -1.1 -1.5 -0.3 0.0 0.0 -0.3 -0.9 0.2 -0.8 -0.5 -1.2 -1.0 -1.6 -0.3 0.0 1.3 0.9 -0.3 -0.4
Mouth/teeth dental problems: Loose teeth 0.2 0.3 1.3 0.5 -0.5 -0.6 -0.6 -0.0 0.0 -0.1 -0.1 -0.5 0.4 -0.4 0.4 -0.3 -0.5 -1.2 -0.4 -0.5 0.5 1.1 0.8 0.1
Emphysema/chronic bronchitis 0.4 0.5 1.6 1.0 0.5 -1.0 -0.4 0.2 0.0 -0.4 0.8 -0.8 -0.5 -1.3 -0.5 -1.0 0.3 -0.1 -0.3 0.4 1.1 0.6 0.2 -0.9
Medication for pain relief, constipation, heartburn 0.9 1.5 4.0 1.6 -1.2 -1.4 -1.7 -1.0 0.0 -0.8 -1.7 -1.8 0.8 -1.6 -1.4 -1.3 -0.1 -1.1 -1.2 -0.4 0.7 1.0 2.0 -0.8
Neck or shoulder pain in last month 1.0 1.5 12.0 -1.4 -0.4 1.1 1.7 1.2 0.0 0.3 3.5 1.9 -1.3 1.1 1.0 0.8 0.5 0.8 0.8 -0.5 -0.2 -0.8 -0.4 0.3
Medication: Blood pressure 0.2 0.4 2.4 0.4 -0.4 -0.6 -0.7 0.8 0.0 -0.3 0.4 -0.3 -0.3 -0.6 -0.6 -0.5 0.3 -0.1 -0.5 0.4 1.5 1.1 0.0 -0.3
Angina (self-reported) 2.4 3.1 7.2 -2.3 0.0 2.5 1.0 0.1 0.0 1.8 -0.4 1.8 -0.7 2.7 2.2 2.5 2.0 2.5 1.7 -0.0 -2.3 -1.4 -1.5 2.3
Migraine (self-reported) 0.3 0.3 1.3 -0.0 0.9 0.3 1.0 0.5 0.0 1.1 0.7 -0.0 -0.7 0.2 0.0 0.3 0.8 0.0 -0.3 1.1 -0.5 0.1 -0.1 0.1
Medication: Ibuprofen 1.0 1.2 3.4 -1.0 0.8 1.1 1.6 1.3 0.0 0.3 1.8 1.4 -1.0 1.1 1.7 1.0 0.4 -0.1 1.5 -0.7 -1.4 -1.0 -0.4 0.1
Medication: Allopurinol 0.5 0.7 3.1 0.8 -0.1 -0.6 -1.3 0.3 0.0 0.8 -0.7 -0.8 -0.0 -0.5 -0.6 -0.1 -1.6 -0.2 -0.6 1.3 0.7 1.8 1.0 0.6
Medication: Omeprazole 0.5 0.6 4.0 0.8 1.2 -0.4 -0.2 0.7 0.0 1.6 0.5 -0.2 -0.6 -0.6 -0.2 -0.3 -0.7 0.6 -0.3 2.0 1.2 0.7 0.7 0.2
Medication: Seretide 50 evohaler 2.5 2.9 7.3 2.0 -1.2 -2.5 -2.7 -0.5 0.0 -0.6 -1.1 -2.5 0.7 -1.8 -1.9 -2.0 -0.8 -1.2 -2.4 1.0 1.8 2.6 1.9 -0.2
Mean time to correctly identify matches 1.2 2.3 6.4 -1.5 0.8 1.7 2.0 1.9 0.0 1.4 1.0 1.4 -1.0 1.7 1.6 1.5 0.6 2.5 1.7 0.7 -1.2 -1.7 -2.4 1.3
Heart disease (mother) 0.5 0.6 2.7 0.5 -1.0 -0.2 -1.7 0.6 0.0 0.7 -0.9 -0.6 1.2 0.0 0.5 0.2 0.2 -0.6 -0.2 0.1 0.1 1.4 0.7 1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.4 1.7 7.1 1.5 -0.2 -1.3 -1.7 0.5 0.0 0.5 -1.5 -1.4 2.4 -0.7 -1.1 -0.6 -0.6 -0.2 -1.8 1.0 1.0 2.7 1.6 0.8
Whole body fat mass 1.0 4.1 9.3 2.7 1.0 -3.0 -1.4 0.7 0.0 -1.1 -0.6 -3.0 1.6 -3.0 -2.6 -2.7 -1.9 -1.0 -2.1 2.2 2.8 2.2 1.6 -1.2
Leg fat mass (right) 1.0 4.0 9.6 2.8 0.5 -2.8 -1.6 0.6 0.0 -1.1 -0.4 -2.8 1.4 -3.1 -2.5 -2.5 -1.6 -0.6 -2.4 1.9 3.0 2.5 1.9 -1.2
Arm predicted mass (right) 1.0 4.9 19.1 2.3 0.8 -2.9 -0.4 -0.2 0.0 -2.4 -1.1 -2.7 4.4 -3.4 -3.4 -2.8 -1.0 -1.2 -1.0 -0.3 2.2 1.8 2.7 -2.4
Pulse rate, automated reading 0.4 1.3 5.8 -0.3 1.0 0.9 2.4 1.0 0.0 -1.1 0.2 1.5 1.9 0.5 0.3 1.0 1.7 1.7 0.7 0.1 -1.6 -1.4 0.1 0.4
Alcohol intake frequency. 0.9 2.1 5.6 -1.2 1.8 1.4 1.2 0.6 0.0 1.5 -0.3 1.3 -2.4 1.3 2.1 1.3 0.6 2.0 1.2 1.7 -0.8 -1.1 -2.1 1.6
Comparative height size at age 10 0.9 5.2 17.6 1.9 -0.6 -3.2 -2.0 -1.2 0.0 -1.4 -3.0 -3.6 2.4 -2.7 -4.2 -3.1 -2.2 -2.2 -0.5 0.3 2.5 1.4 2.4 -1.5
Number of full sisters 0.6 0.7 1.9 -0.7 0.3 1.0 1.2 0.3 0.0 0.4 1.4 1.1 -1.1 0.8 0.8 0.9 1.0 1.0 -0.1 -0.2 -0.9 -1.1 -0.8 0.4
Suffer from ‘nerves’ 1.7 2.6 10.9 -1.2 1.4 2.1 1.7 1.1 0.0 1.3 0.2 2.1 0.1 1.1 2.1 2.0 2.9 3.3 1.4 0.9 -0.9 -1.1 -1.5 0.8
Overall health rating 0.3 0.7 3.8 0.3 0.0 1.1 0.1 0.1 0.0 0.4 0.4 0.7 -0.4 0.1 1.5 1.1 1.4 2.0 -1.0 1.0 0.2 0.3 -0.4 0.3
Chest pain or discomfort 1.7 2.4 6.1 2.3 -1.5 -1.5 -2.5 -1.6 0.0 -1.1 -1.9 -1.9 -0.1 -1.8 -0.8 -1.3 -1.1 -1.4 -2.4 -0.5 0.6 1.8 2.0 -1.1
Had major operations 0.3 0.3 1.7 0.2 -1.2 -0.0 -0.9 0.2 0.0 0.1 -0.6 -0.3 0.3 0.2 1.1 0.3 0.1 0.0 -0.3 -0.2 0.3 1.3 0.9 0.5
Age at last live birth 1.0 1.4 6.6 1.9 -1.2 -0.4 -0.8 0.3 0.0 -1.5 0.8 -0.4 -0.1 -1.9 -1.4 -0.5 0.5 -0.8 -0.5 -1.0 1.9 1.2 0.7 -2.6
Family relationship satisfaction 2.1 2.6 10.3 -0.6 -0.7 2.2 1.5 -0.1 0.0 -1.4 1.8 2.1 -1.9 0.4 1.9 1.7 3.2 2.3 0.7 -1.9 -1.4 -1.9 -0.9 -0.7
Leg pain on walking 0.1 0.1 0.3 0.3 -0.4 0.3 0.3 -0.1 0.0 0.1 0.4 -0.2 -0.5 -0.0 -0.2 0.5 -0.3 0.5 0.2 0.5 -0.1 0.5 -0.3 0.2
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 1.7 0.3 0.5 0.2 -0.1 -0.1 0.0 -0.1 0.2 -0.4 -1.3 -0.1 0.2 0.2 -0.3 -0.4 -0.8 0.3 -0.0 0.1 1.1 -0.2
Commuting to job workplace: Car/motor vehicle 1.3 1.5 3.9 -2.0 0.6 0.9 0.7 0.3 0.0 1.5 1.2 1.2 -1.0 2.0 1.0 0.8 1.2 0.3 1.4 0.1 -1.8 -1.1 -1.9 1.4
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 2.0 -0.1 -0.4 -0.2 0.5 -1.0 0.0 -1.4 0.6 0.3 -1.4 -0.5 -0.6 -0.6 -0.5 -0.5 0.6 -0.6 0.4 -0.9 -0.5 -1.3
Medication: Aspirin 2.3 3.0 6.1 -2.3 1.1 2.1 2.4 1.8 0.0 1.3 2.2 2.3 -0.1 2.0 1.3 1.9 1.3 2.1 2.5 -0.2 -1.1 -1.6 -2.1 1.2
Supplements: Vitamin C 0.3 0.3 2.5 -0.5 -0.8 0.0 -0.3 0.0 0.0 0.1 0.6 0.0 1.6 0.6 -0.6 0.3 -0.4 0.1 -0.3 -0.7 0.3 -0.0 1.0 0.9
Knee pain experienced in last month 0.5 0.7 2.3 0.8 -1.5 -0.7 -0.1 -0.0 0.0 -1.5 0.6 -1.0 -0.3 -0.9 -0.5 -0.9 -1.4 -0.8 -0.5 -0.6 1.2 0.4 -0.7 -1.2
Hypertension (Self-reported) 0.1 0.4 1.2 -0.2 -1.1 0.5 0.4 0.8 0.0 0.1 0.1 0.7 -0.2 0.2 0.3 0.8 0.9 1.1 1.0 0.4 0.5 0.4 -0.8 0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 2.2 -0.4 0.9 -0.0 0.2 0.9 0.0 1.0 0.2 0.1 1.0 0.8 0.2 0.2 0.8 0.4 0.3 1.5 -0.7 0.3 0.6 1.1
Illnesses of father: Heart disease 3.7 5.1 10.4 3.2 -1.6 -3.0 -2.5 -0.0 0.0 -1.8 -1.0 -2.9 0.3 -3.1 -2.8 -3.0 -2.5 -1.5 -3.0 0.2 3.1 2.1 2.0 -1.9
Illnesses of siblings: Diabetes 2.3 2.8 9.8 -2.3 -1.8 2.1 1.5 0.0 0.0 -0.1 2.3 2.2 -0.3 2.0 1.7 1.6 0.7 0.7 3.1 -2.0 -1.1 -1.3 -2.2 1.1
Smoking status: Previous 0.1 0.2 0.7 0.3 0.1 -0.7 -0.5 0.5 0.0 0.3 -0.6 -0.7 0.6 -0.1 -0.8 -0.8 0.2 0.2 -0.4 0.2 0.3 0.3 0.5 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 1.6 3.3 7.2 1.3 -1.7 -2.3 -1.9 -2.7 0.0 -2.4 -1.1 -2.4 1.5 -1.8 -2.3 -2.4 -1.0 -2.6 -1.4 -1.9 0.7 0.7 1.5 -1.5
Whole body fat-free mass 1.2 7.0 22.2 2.6 0.6 -3.5 -0.2 -0.6 0.0 -3.3 -1.6 -3.3 4.7 -4.0 -4.2 -3.4 -1.4 -1.4 -0.9 -0.9 2.6 1.4 3.2 -3.1
Leg fat-free mass (right) 0.9 5.0 21.7 2.0 0.9 -2.7 0.6 -0.6 0.0 -3.4 -1.7 -2.6 4.7 -3.3 -3.5 -2.7 -1.0 -0.9 -0.3 -0.7 2.0 0.5 2.5 -2.6
Arm fat percentage (left) 0.3 1.2 5.6 1.3 1.5 -1.3 -0.3 1.2 0.0 -0.1 0.3 -1.3 0.8 -1.4 -0.9 -1.0 -0.8 0.3 -1.2 2.4 1.7 1.0 0.3 -0.0
Average weekly red wine intake 3.4 5.0 10.6 2.2 -1.0 -3.1 -2.8 -1.4 0.0 -1.0 -2.5 -3.3 2.3 -2.2 -2.1 -2.9 -2.8 -2.8 -2.4 -0.7 1.5 2.0 3.1 -1.5
Handedness (chirality/laterality): Left-handed 2.4 2.9 9.8 2.0 -1.2 -1.8 -0.7 -0.9 0.0 -2.7 0.3 -1.6 -0.5 -2.2 -2.2 -1.8 -0.9 -1.2 -1.6 -2.0 1.8 1.3 3.1 -2.2
Mood swings 0.7 1.2 4.2 -0.1 1.5 1.5 1.2 1.2 0.0 1.3 1.0 1.3 -0.5 0.5 1.9 1.4 1.2 2.1 0.3 1.3 -0.5 -0.3 -0.5 0.2
Loneliness, isolation 0.4 0.6 2.5 -0.6 -0.3 1.2 0.3 0.6 0.0 0.4 0.9 1.2 0.4 0.6 1.3 1.0 1.6 0.6 0.5 -0.0 -0.6 -0.3 -1.1 0.3
Long-standing illness, disability or infirmity 0.5 0.7 3.8 -0.1 0.4 0.8 0.2 1.2 0.0 2.0 0.6 0.4 -0.0 0.5 1.8 0.8 0.2 0.6 0.4 1.3 -0.0 0.5 0.3 1.2
Ever had bowel cancer screening 0.3 0.3 0.9 -0.4 -0.9 0.4 0.3 -0.4 0.0 0.4 0.6 0.6 -0.7 0.7 0.8 0.4 -0.5 0.9 0.2 0.3 -0.0 -0.5 -0.3 0.8
Diabetes diagnosed by doctor 1.0 1.6 5.1 -1.1 -0.5 1.7 1.1 1.4 0.0 0.5 0.8 1.8 -0.8 1.3 2.3 1.6 0.8 0.8 2.1 -0.7 -1.0 0.0 -2.0 1.2
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.7 3.6 0.3 -0.6 0.7 1.9 1.6 0.0 -0.7 0.8 0.4 -0.4 -0.5 0.4 0.7 1.1 0.6 0.5 -1.5 -0.4 -0.5 -0.4 -0.7
Friendships satisfaction 0.6 0.7 4.0 1.2 -0.4 -0.2 -0.1 0.5 0.0 -1.3 1.2 0.1 -0.5 -1.5 -0.1 -0.5 0.5 -0.1 -0.9 -0.5 0.7 -0.1 1.2 -2.0
Qualifications: nursing, teaching 1.0 1.6 4.9 1.6 -1.6 -1.4 -1.1 -1.0 0.0 -1.0 -2.2 -1.4 1.0 -1.5 -0.9 -1.4 -0.4 -1.8 -1.1 -1.1 0.6 1.0 0.8 -1.3
Commuting to job workplace: Walk 0.2 0.2 1.1 -0.6 0.2 -0.4 0.6 -0.3 0.0 -0.1 0.2 -0.3 1.1 0.4 -0.4 -0.2 -0.0 -0.6 -0.4 0.3 -0.6 -0.2 -0.2 0.6
Eye problems/disorders: Cataract 0.6 0.7 2.6 -1.1 -0.1 0.8 1.1 -1.6 0.0 -0.8 0.1 0.6 -0.6 0.6 -0.1 0.8 0.9 0.6 0.3 -1.6 -1.2 -1.3 0.4 -0.1
Mouth/teeth dental problems: Mouth ulcers 2.5 3.9 9.9 -1.8 3.1 2.1 2.2 2.3 0.0 3.2 0.9 2.2 0.9 1.9 2.0 2.4 1.9 3.0 1.0 2.2 -1.6 -0.6 0.1 1.8
Medication for cholesterol 0.2 0.2 0.7 -0.4 0.2 -0.6 -0.5 -0.6 0.0 0.2 0.3 -0.4 0.8 0.1 -0.5 -0.6 0.5 -0.9 -0.7 -0.5 -0.5 0.3 0.6 0.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 2.8 -1.1 0.5 1.1 1.3 1.1 0.0 0.2 1.7 0.9 -0.1 0.9 1.0 1.1 -0.2 0.7 0.6 0.1 -0.5 -0.6 -0.5 0.4
Back pain experienced in last month 0.1 0.2 0.9 0.1 0.3 0.5 -0.3 0.5 0.0 0.9 0.3 0.3 0.1 -0.1 0.3 0.6 0.3 0.2 -0.5 1.0 0.0 0.7 0.1 0.7
Mineral and other dietary supplements 0.5 0.6 2.3 -0.8 0.8 0.6 0.9 -0.0 0.0 -0.4 1.0 1.1 -0.8 0.5 1.5 0.2 0.2 -0.5 0.8 -0.5 -1.2 -1.1 -1.2 -0.5
Breast cancer (self-reported) 1.1 1.3 7.2 -0.3 1.3 -0.8 -0.7 1.5 0.0 2.2 0.1 -0.1 2.7 0.7 -0.1 -0.4 -0.8 -0.8 1.0 1.6 0.2 1.7 0.7 1.3
Asthma (self-reported) 3.6 7.2 15.5 3.6 -1.0 -3.9 -3.6 0.9 0.0 -0.7 -1.5 -3.9 1.2 -2.9 -3.2 -3.0 -2.8 -2.4 -3.0 1.6 3.1 3.7 3.5 -0.6
Osteoporosis (self-reported) 2.4 2.9 9.9 1.3 0.1 -2.4 -2.9 -1.0 0.0 1.0 -0.5 -2.4 -2.3 -0.7 -0.8 -2.0 -3.1 -2.8 -1.2 1.3 1.5 1.9 0.3 0.2
Osteoarthritis (self-reported) 0.4 0.6 3.2 0.8 0.5 -0.1 0.7 0.5 0.0 -0.4 1.8 -0.3 -0.7 -0.9 -0.9 -0.1 -0.6 1.1 0.2 0.5 1.5 0.1 0.5 -0.6
Medication: Aspirin 2.5 3.3 6.3 -2.5 0.9 2.2 2.4 1.8 0.0 1.2 2.4 2.3 -0.2 2.1 1.5 1.9 1.5 2.0 2.5 -0.3 -1.2 -1.6 -2.5 1.4
Medication: Gliclazide 1.7 1.9 4.0 -1.6 1.0 1.7 2.0 1.7 0.0 0.8 1.6 1.5 -0.1 1.8 1.9 1.6 0.5 0.3 2.0 -0.3 -1.5 -0.8 -1.7 1.3
Illnesses of father: None of the above (group 1) 1.2 1.5 4.4 -2.1 0.2 1.5 1.6 -0.8 0.0 0.6 0.4 1.8 -0.9 1.7 1.1 1.1 1.1 -0.1 1.6 -0.7 -1.9 -1.7 -1.4 0.5
Smoking status: Current 1.2 1.8 6.1 -1.9 0.8 1.4 1.6 1.1 0.0 0.9 -0.3 1.6 -0.4 2.1 1.9 1.2 0.4 0.0 1.4 0.7 -2.5 -1.5 -2.0 0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 3.3 1.3 0.7 -0.5 -0.3 0.1 0.0 -1.6 -0.1 -0.7 1.8 -1.8 -1.0 -0.5 -0.4 -0.9 -0.1 -0.6 1.4 0.7 0.2 -1.6
Whole body water mass 1.2 6.9 22.8 2.5 0.6 -3.4 -0.1 -0.5 0.0 -3.3 -1.6 -3.2 4.8 -4.0 -4.2 -3.4 -1.4 -1.3 -0.9 -0.9 2.5 1.4 3.2 -3.0
Leg predicted mass (right) 0.9 5.0 22.0 2.0 1.0 -2.7 0.6 -0.6 0.0 -3.3 -1.6 -2.6 4.7 -3.3 -3.5 -2.6 -0.9 -0.9 -0.2 -0.7 1.9 0.5 2.5 -2.6
Arm fat mass (left) 0.7 2.8 7.2 2.1 1.5 -2.4 -0.5 0.9 0.0 -1.2 -0.1 -2.2 1.8 -2.7 -2.3 -2.2 -1.1 -0.2 -1.5 1.8 2.4 1.4 1.5 -1.3
Number of self-reported non-cancer illnesses 0.8 1.3 4.4 1.2 0.1 -1.3 -1.0 1.4 0.0 0.6 0.3 -1.3 0.5 -0.7 -0.8 -0.9 -1.7 -0.3 -1.0 2.1 1.6 2.0 1.6 0.6
Average weekly champagne plus white wine intake 0.7 0.9 2.8 1.2 -0.1 -0.9 -0.9 -0.9 0.0 -0.7 -0.6 -1.1 1.4 -1.4 -1.7 -0.9 -0.4 -0.5 -1.1 0.4 1.1 0.3 1.4 -0.8
Miserableness 0.3 0.5 2.0 1.2 -0.1 -0.2 -0.2 -0.4 0.0 0.5 -0.4 -0.7 -0.1 -0.9 -0.1 -0.1 0.7 0.4 -1.4 1.1 0.7 0.9 1.0 -0.4
Guilty feelings 0.4 0.6 2.7 0.4 0.4 0.6 -0.0 1.3 0.0 0.5 1.5 0.8 -0.4 -0.5 0.8 0.2 1.6 0.9 -0.3 -0.2 0.3 0.6 0.7 -1.2
Wears glasses or contact lenses 1.2 1.4 7.2 0.9 -0.6 -0.9 -1.3 0.7 0.0 1.5 -0.8 -0.8 1.1 -0.3 0.0 -0.3 0.4 0.9 -1.1 1.4 0.9 2.5 2.7 1.0
Ever taken oral contraceptive pill 0.5 0.5 2.2 1.2 -1.5 -0.3 -1.1 -0.4 0.0 -0.9 -0.4 -0.7 -0.4 -0.7 -0.3 -0.2 0.4 -0.5 -1.3 -0.5 0.4 0.6 0.5 -0.7
Hearing aid user 1.4 1.5 3.7 -1.6 -0.1 1.9 1.2 -0.6 0.0 0.0 0.5 1.7 -0.7 1.5 1.6 1.7 0.9 1.4 0.6 -1.5 -1.9 -1.9 -0.5 0.6
Mother’s age at death 0.6 0.8 2.7 1.1 0.1 -1.1 -0.4 -0.6 0.0 -0.2 -1.3 -0.9 -0.2 -1.5 -1.6 -1.2 0.5 -0.3 -1.0 0.1 0.8 0.3 1.0 -1.3
Financial situation satisfaction 0.9 1.2 3.6 -0.2 0.1 1.4 1.3 0.9 0.0 -0.8 1.5 1.6 -1.6 0.4 0.5 1.1 1.9 1.0 -0.0 -0.2 -0.6 -1.1 -1.9 -0.6
Tinnitus: Yes, now most or all of the time 2.0 2.4 14.1 0.6 -3.8 -1.1 -1.6 -2.8 0.0 -2.0 -0.7 -1.1 0.5 -0.5 -1.8 -1.0 -1.5 -1.8 -0.8 -2.4 1.0 0.6 0.5 -0.5
Commuting to job workplace: Public transport 0.4 0.5 1.5 -0.3 -1.1 0.5 0.3 -0.4 0.0 -1.0 0.1 0.6 1.2 0.5 0.5 0.5 0.3 -0.2 0.5 -1.1 -0.5 -1.2 -1.2 -0.0
Eye problems/disorders: Glaucoma 0.5 0.6 1.6 1.1 0.5 -0.6 -0.0 1.2 0.0 -0.1 -0.5 -0.9 1.2 -0.8 -0.5 -0.4 -0.7 0.4 -1.2 0.9 0.8 0.8 1.3 -0.0
Medication: Blood pressure 1.4 2.6 7.6 -1.9 0.4 1.7 1.8 1.4 0.0 1.0 0.6 2.0 -0.1 2.3 1.7 1.8 0.5 1.4 2.8 0.7 -1.9 -1.3 -2.3 2.2
Pain type(s) experienced in last month: Hip pain 0.3 0.4 2.0 0.1 0.0 0.1 -0.9 0.1 0.0 1.2 -1.2 -0.3 0.2 0.1 0.3 0.2 -0.9 -0.1 -0.4 1.4 -0.1 1.0 0.5 0.6
Supplements: Fish oil (including cod liver oil) 0.5 0.7 3.8 0.8 -2.0 -0.5 -0.7 -0.5 0.0 -0.7 -0.3 -1.0 0.2 -0.9 -1.9 -0.4 -0.0 0.4 -0.5 -0.7 1.2 0.8 0.3 0.0
High cholesterol (Self-reported) 0.3 0.6 3.5 0.3 0.5 0.3 0.7 1.9 0.0 0.7 1.0 0.2 -1.0 -0.4 1.1 0.2 0.6 1.6 0.2 0.4 0.5 0.3 -0.2 -0.6
Medication: Bendroflumethiazide 0.3 0.4 1.8 0.7 -0.2 -0.8 -0.4 0.1 0.0 -0.6 -0.6 -0.5 -0.2 -1.0 -0.8 -0.7 -0.9 -0.3 1.1 0.6 1.3 0.2 -0.4 -0.5
Medication: Paracetamol 0.2 0.3 1.5 0.4 0.3 -0.0 -0.3 0.3 0.0 0.5 -0.1 -0.1 -0.4 -0.2 0.2 0.1 -1.2 0.2 -1.1 1.0 0.5 0.6 -0.3 0.1
Medication: Lisinopril 0.7 0.9 3.4 -1.0 0.3 0.5 0.1 -0.1 0.0 0.6 -1.2 0.3 1.2 1.6 1.0 0.8 -0.7 0.1 1.5 0.2 -1.9 -0.7 -0.8 1.8
Medication: Atorvastatin 0.6 0.7 2.8 -0.8 0.2 0.7 -0.1 1.1 0.0 1.7 -0.9 1.0 0.4 1.4 1.1 0.9 0.2 0.2 0.5 0.9 -0.6 0.5 -0.8 1.5
Illnesses of father: High blood pressure 0.3 0.3 1.2 0.2 -0.8 0.3 -0.1 -0.7 0.0 -1.1 -0.6 0.6 -0.6 -0.1 -0.2 0.0 -0.3 0.4 -0.1 -0.5 -0.1 -1.0 -1.1 -0.6
Alcohol drinker status: Never 0.5 0.7 2.2 -0.6 1.2 0.4 0.5 1.3 0.0 1.5 -0.6 0.2 -0.4 0.6 1.3 0.5 -0.4 1.0 0.1 1.3 0.4 0.3 -0.8 0.9
Ever smoked 0.3 0.6 1.9 -0.8 0.8 0.6 0.4 0.7 0.0 0.7 -0.9 0.8 1.4 1.1 0.6 0.5 0.4 -0.2 0.7 0.8 -1.3 -0.3 -0.9 -0.0
Basal metabolic rate 1.3 7.4 19.9 2.8 0.5 -3.7 -0.4 -0.6 0.0 -3.4 -1.6 -3.5 4.5 -4.1 -4.3 -3.7 -1.7 -1.6 -1.1 -0.7 2.8 1.5 3.2 -3.1
Leg fat percentage (left) 0.6 2.2 9.8 2.0 0.3 -1.6 -1.6 1.1 0.0 0.8 -0.3 -1.8 0.0 -1.6 -0.8 -1.1 -1.0 0.2 -2.3 3.1 2.1 2.5 0.8 0.5
Arm fat-free mass (left) 1.4 7.2 17.6 2.9 0.5 -3.7 -0.8 -0.4 0.0 -2.8 -1.5 -3.5 4.2 -4.1 -4.2 -3.6 -1.9 -1.7 -1.5 -0.4 3.0 2.0 3.2 -2.9
Number of operations (self-reported) 0.2 0.3 1.2 -0.5 -0.8 0.2 -0.1 -0.1 0.0 -0.4 0.5 -0.0 0.6 0.5 -0.0 0.5 -0.6 0.6 -0.1 -0.6 0.2 0.6 1.1 0.9
Average weekly beer plus cider intake 0.5 0.8 3.0 -1.3 0.5 0.8 0.7 0.3 0.0 0.4 -0.2 0.9 0.9 1.4 0.9 1.1 0.6 -0.1 1.2 0.1 -1.7 -0.5 0.1 1.2
Irritability 0.5 0.9 4.0 1.7 -0.9 -0.5 -1.3 1.0 0.0 0.9 -0.0 -0.9 0.3 -1.1 -0.5 -0.2 -0.2 -0.5 -1.2 1.0 1.3 2.0 0.5 0.0
Risk taking 1.3 1.9 4.2 1.6 1.1 -1.3 -1.1 -0.1 0.0 0.3 -2.0 -2.0 2.0 -1.2 -1.3 -1.0 -1.1 -1.3 -2.0 1.8 0.8 1.9 1.4 0.0
Ever had prostate specific antigen (PSA) test 0.4 0.4 1.6 0.4 -0.1 -0.8 -0.4 0.3 0.0 0.9 -0.7 -0.4 0.4 0.0 -0.4 -0.6 -1.3 0.4 -0.4 1.2 -0.1 1.0 1.1 0.7
Fractured/broken bones in last 5 years 8.4 10.9 19.7 4.2 -2.6 -4.0 -2.6 -2.5 0.0 -2.7 -0.2 -4.3 -3.7 -4.4 -4.1 -4.3 -3.7 -3.1 -3.4 -1.3 4.4 2.0 2.3 -4.0
Age started oral contraceptive pill 0.7 0.8 2.3 1.5 0.4 -1.1 -1.0 0.4 0.0 0.4 -0.9 -1.3 0.7 -1.2 -1.1 -0.9 -1.2 -0.4 -0.3 0.6 1.3 1.1 1.0 -0.4
Diastolic blood pressure, automated reading 1.1 3.4 9.0 2.8 -0.9 -2.1 -1.7 0.0 0.0 -0.8 -2.7 -2.1 0.6 -2.3 -2.5 -2.1 -0.8 -1.0 -3.0 1.3 2.3 2.3 1.2 -1.4
Ever depressed for a whole week 0.9 1.1 4.5 1.9 0.2 -0.3 -0.9 0.8 0.0 -0.7 0.3 -0.5 0.3 -1.9 -0.0 -0.3 -0.9 0.3 -0.9 0.8 1.6 1.1 2.1 -1.3
Unable to work because of sickness or disability 0.3 0.3 1.6 1.1 0.4 -0.2 -0.7 0.4 0.0 -0.1 -0.2 -0.4 -0.1 -0.8 0.2 -0.0 0.0 0.3 -0.7 0.7 0.2 1.2 1.3 -0.3
Commuting to job workplace: Cycle 1.0 1.2 3.6 1.1 0.2 -1.1 -1.1 0.2 0.0 0.1 -0.9 -0.9 1.6 -0.9 -1.8 -0.8 -0.9 -0.6 -1.1 1.9 1.6 1.7 1.1 -0.1
Myopia 2.1 3.0 9.3 2.1 -0.7 -2.3 -1.6 -0.3 0.0 -1.4 -0.6 -2.0 1.9 -1.8 -2.1 -2.2 -2.0 -3.1 -1.8 -0.4 1.0 1.9 2.2 -1.2
Vascular/heart problems diagnosed by doctor 0.3 0.8 2.1 0.7 0.4 -1.0 -0.5 -1.1 0.0 -0.8 -0.4 -1.1 0.0 -1.0 -0.9 -1.4 -1.1 -1.5 -1.2 -0.7 0.1 -0.1 0.9 -1.4
Cholesterol lowering medication 0.2 0.3 1.1 1.0 -0.4 -0.6 -0.7 0.6 0.0 -0.3 -0.5 -0.7 -0.0 -0.7 0.4 -0.5 -1.0 -0.2 0.1 0.5 0.9 0.9 -0.2 -0.1
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 2.9 0.8 0.9 -0.5 -0.5 0.0 0.0 1.6 -0.3 -0.5 -0.4 -0.6 -0.2 -0.5 -0.6 0.1 -0.6 1.7 1.1 1.1 0.6 0.2
Pain experienced in last month 0.2 0.3 1.9 -0.3 0.5 -0.5 0.1 -0.7 0.0 -0.0 -1.4 -0.1 0.1 0.1 -1.1 -0.4 -0.3 -0.2 0.6 0.3 -0.6 -0.5 0.2 0.2
Supplements: Calcium 1.1 1.2 4.9 1.1 0.5 -1.3 -1.4 -0.3 0.0 1.2 -0.7 -1.2 -0.1 -1.0 -1.0 -0.8 -0.7 -0.3 -0.8 1.4 1.6 2.2 1.7 0.6
Basal cell carcinoma (self-reported) 0.4 0.4 2.0 0.5 0.2 -0.2 0.1 0.1 0.0 -0.9 0.7 0.1 1.4 -1.1 -0.9 -0.3 0.5 0.6 -0.4 0.1 1.2 0.2 0.5 -1.0
Heart attack/myocardial infarction (self-reported) 0.1 0.2 0.7 -0.5 -0.8 0.3 -0.3 -0.8 0.0 0.6 0.0 -0.0 -0.5 0.4 -0.1 0.5 0.3 0.7 -0.4 -0.2 0.1 -0.1 0.1 0.7
Deep venous thrombosis (DVT) (self-reported) 0.2 0.3 0.9 0.6 -0.7 0.1 0.3 -0.3 0.0 -1.0 0.5 -0.2 -0.5 -0.7 -0.9 0.1 -0.5 0.0 -0.2 -0.6 0.8 0.0 0.7 -0.8
Heart disease (siblings) 0.8 1.0 3.6 -0.4 1.1 0.9 0.4 0.4 0.0 1.4 -0.8 0.5 1.6 0.7 1.0 1.3 0.7 1.9 0.7 1.2 -0.7 0.2 0.1 1.5
Alcohol drinker status: Previous 1.5 1.7 6.2 -1.2 2.5 1.0 2.2 1.4 0.0 1.0 1.4 1.1 -0.2 1.2 1.4 0.9 1.2 1.5 1.8 1.1 -0.7 -1.6 0.1 0.7
Pack years of smoking 0.1 0.1 0.8 0.2 -0.3 -0.2 -0.3 0.2 0.0 0.4 -0.7 -0.2 0.2 0.1 0.4 0.1 -0.6 0.0 0.0 0.4 -0.3 0.2 -0.0 0.9
Impedance of whole body 1.0 4.9 19.1 1.7 -3.4 -2.2 -3.8 -2.6 0.0 -0.5 -0.7 -2.4 -4.4 -1.1 -1.6 -2.3 -2.9 -3.4 -1.9 -0.1 1.6 0.9 -0.3 -0.5
Leg fat mass (left) 0.8 3.3 7.9 2.5 0.7 -2.5 -1.2 0.8 0.0 -0.9 -0.3 -2.5 1.4 -2.8 -2.2 -2.2 -1.3 -0.4 -2.0 2.0 2.8 2.3 1.6 -1.1
Arm predicted mass (left) 1.7 8.8 21.3 3.3 0.2 -4.1 -1.1 -0.7 0.0 -3.1 -1.7 -3.8 4.2 -4.5 -4.6 -4.1 -2.1 -2.0 -1.9 -0.5 3.3 2.3 3.5 -3.3