TWAS hub - CCND1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1291	0.0470	3.4e-03	0.000	NA	0.020	NA	-0.003	2.9e-01	NA	9.3e-03	NA	7.5e-01
2	YFS	Blood	0.0516	0.0129	2.7e-11	0.020	0.042	0.042	0.042	0.042	2.1e-07	1.2e-13	1.2e-13	1.5e-13	8.7e-14
3	TCGA	Thyroid Carcinoma	0.0480	0.0260	8.6e-03	0.031	-0.001	-0.001	NA	0.016	5.1e-04	4.0e-01	4.2e-01	NA	8.8e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Breast Cancer	7.5	18.0	33.2	0.9	5.8	-4.5
Comparative body size at age 10	6.3	17.3	36.6	1.6	-3.6	6.0
Impedance of leg (left)	6.0	28.9	68.3	-2.6	3.4	-8.3
Impedance of leg (right)	5.4	25.9	63.5	-2.4	2.9	-8.0
Birth weight	4.7	10.2	24.8	1.9	-1.4	5.0
Commuting to job workplace: Public transport	4.4	5.2	12.7	3.6	1.7	-0.2
Impedance of whole body	4.1	20.9	40.6	-3.4	3.2	-6.4
Leg fat-free mass (left)	3.6	19.1	51.5	0.8	-2.3	7.2
Leg predicted mass (left)	3.6	19.2	51.5	0.7	-2.4	7.2
BMI	3.4	19.6	38.2	4.0	-2.1	6.2
Leg fat-free mass (right)	3.4	18.4	49.8	0.7	-2.2	7.1
Leg predicted mass (right)	3.4	18.3	49.4	0.7	-2.2	7.0
Waist Hip Ratio (WHR)	3.1	13.8	25.3	-1.5	3.8	-5.0
Commuting to job workplace: Car/motor vehicle	3.1	3.6	3.9	-1.9	-2.0	1.8
Basal cell carcinoma (self-reported)	3.0	3.5	8.6	-1.2	2.9	-0.7
Glaucoma (self-reported)	2.8	3.3	7.3	1.2	2.7	-1.1
Body mass index (BMI)	2.7	11.6	19.4	3.0	-2.5	4.4
Whole body fat-free mass	2.7	15.2	39.1	0.7	-2.5	6.2
Eye problems/disorders: Glaucoma	2.7	3.2	8.0	0.7	2.8	-1.0
Arm fat mass (right)	2.6	10.8	23.4	1.9	-2.3	4.8
Whole body water mass	2.6	15.0	38.7	0.8	-2.4	6.2
Basal metabolic rate	2.6	14.6	36.5	0.8	-2.6	6.0
Medication for cholesterol, blood pressure or diabetes	2.5	4.1	6.9	-0.8	-2.6	2.2
Nervous feelings	2.4	4.6	6.4	2.5	-2.5	1.0
Forced expiratory volume in 1-second (FEV1)	2.4	8.0	22.8	0.9	4.8	0.5
Prostate Cancer	2.3	3.3	5.3	-2.3	2.1	0.0
Diverticular disease/diverticulitis (self-reported)	2.3	2.8	5.6	-1.2	-1.1	2.4
Hip circumference	2.3	10.0	25.4	0.8	-2.0	5.0
Ulcerative Colitis	2.2	3.1	6.6	-1.7	-2.6	0.0
Mouth/teeth dental problems	2.2	3.4	5.5	-2.3	0.9	-2.0
Weight	2.2	11.0	26.2	1.1	-2.3	5.1
Vitamin and mineral supplements	2.1	2.8	4.4	0.7	-2.1	-1.9
Trunk fat-free mass	2.1	12.0	31.1	0.5	-2.2	5.6
Mouth/teeth dental problems: Dentures	2.1	3.6	10.0	3.2	-0.1	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.7	19.4	0.3	4.4	0.7
Trunk predicted mass	2.1	11.7	30.1	0.5	-2.2	5.5
Arm fat mass (left)	2.1	8.8	18.5	1.6	-2.3	4.3
Arm predicted mass (left)	2.1	10.7	25.3	0.9	-2.5	5.0
Eye problems/disorders: None of the above	2.0	2.3	4.2	1.1	-1.2	2.1
Age at last live birth	2.0	2.9	3.0	-1.7	1.6	-1.7
Unable to work because of sickness or disability	2.0	2.6	4.4	-2.1	-1.5	-1.1
Prospective memory result	1.9	2.4	4.2	0.4	1.7	-2.0
Impedance of arm (left)	1.9	8.7	12.0	-3.2	1.9	-3.5
Arm fat-free mass (left)	1.9	9.6	22.6	1.0	-2.2	4.8
Blood White Count	1.8	13.3	31.8	-1.0	2.7	-5.6
Systolic Blood Pressure	1.8	8.9	13.2	-0.9	3.6	-3.5
Lung FVC	1.8	9.0	16.8	3.1	4.1	0.4
Multivitamins +/- minerals	1.8	2.2	4.0	-0.3	1.6	2.0
Forced vital capacity (FVC)	1.8	6.8	19.3	1.1	4.4	0.3
Arm fat percentage (right)	1.8	7.1	14.4	1.9	-1.9	3.8
Breastfed as a baby	1.8	2.2	5.2	-2.3	-1.1	0.4
Arm fat-free mass (right)	1.8	9.1	20.9	0.8	-2.4	4.6
Osteoarthritis (self-reported)	1.8	2.3	5.5	-0.7	-2.4	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.8	3.8	8.8	1.5	3.0	0.4
Alcohol drinker status: Never	1.8	2.1	4.2	0.8	-1.3	2.0
Ever depressed for a whole week	1.8	2.2	5.1	1.2	0.1	2.3
Alzheimer’s Disease (in father)	1.7	1.8	4.4	-0.7	2.1	-0.8
Cardiovascular Disease	1.7	5.5	15.1	0.7	3.9	-1.0
High blood pressure (siblings)	1.7	2.5	4.2	-0.8	2.1	-1.6
Illnesses of father: High blood pressure	1.7	2.1	3.4	-1.8	1.3	1.1
Falls in the last year	1.6	2.1	3.6	0.6	-1.6	1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.4	6.7	2.6	-0.5	0.6
Arm predicted mass (right)	1.6	8.1	18.6	0.7	-2.3	4.3
Family relationship satisfaction	1.6	2.0	2.7	-1.6	1.3	-1.3
Knee pain experienced in last month	1.6	2.6	6.6	0.7	-2.6	0.8
Arm fat percentage (left)	1.6	6.2	11.9	1.7	-1.9	3.5
Average weekly red wine intake	1.6	2.4	4.9	-0.8	1.3	-2.2
Mood swings	1.6	2.8	4.5	1.9	-2.1	0.7
Breast cancer (self-reported)	1.6	1.9	4.3	0.3	-1.1	2.1
Medication: Gliclazide	1.6	1.8	3.1	1.2	-0.9	1.8
Bilateral oophorectomy (both ovaries removed)	1.5	1.7	3.7	0.4	-1.1	1.9
Medication: Blood pressure	1.5	2.7	4.1	0.1	2.0	-2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	4.8	0.0	2.2	-0.7
Mineral and other dietary supplements	1.5	2.0	4.3	0.9	-2.1	-0.9
Illnesses of father: None of the above (group 1)	1.5	1.9	3.7	1.4	-1.9	-0.0
Coronary Artery Disease (CAD)	1.4	1.6	4.9	-0.1	2.2	0.0
Lupus	1.4	2.1	6.0	0.6	-2.5	0.0
Frequency of depressed mood in last 2 weeks	1.4	1.9	4.1	2.0	-1.2	0.2
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	2.6	0.6	1.2	-1.6
Serious illness, injury or assault to yourself	1.4	1.7	2.9	1.3	-1.7	0.7
Hearing difficulty/problems with background noise	1.4	2.2	6.1	-0.2	-2.5	0.8
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.1	8.9	3.0	-0.6	0.1
Impedance of arm (right)	1.4	6.7	8.9	-3.0	1.9	-2.7
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.2	4.1	2.0	-1.6	0.2
Birth weight of first child	1.4	2.5	6.2	0.9	-0.8	2.5
Supplements: Vitamin C	1.4	1.6	3.3	-0.6	1.8	1.1
Smoking status: Previous	1.4	2.1	3.2	1.1	1.8	-1.3
Medication: Atorvastatin	1.4	1.7	4.6	0.7	2.1	0.0
Crohns Disease (2017)	1.3	2.8	7.3	1.0	0.2	-2.7
Medication: Co-codamol	1.3	1.5	2.8	1.7	-1.0	0.8
Hair/balding pattern: Pattern 2	1.3	1.6	4.2	-0.7	-2.1	-0.4
Worrier / anxious feelings	1.3	2.5	6.6	2.6	0.9	-0.1
Hair/balding pattern: Pattern 4	1.3	3.1	8.0	-0.3	-2.8	1.1
Forced vital capacity (FVC), Best measure	1.3	4.8	14.1	-0.0	3.8	0.6
Mouth/teeth dental problems: Loose teeth	1.3	1.5	2.7	0.7	-1.6	1.2
Heart disease (mother)	1.3	1.6	3.8	1.9	0.9	-0.3
Leg fat mass (right)	1.3	5.2	9.4	1.9	-1.6	3.1
Ever had bowel cancer screening	1.3	1.6	4.0	-0.7	-0.4	2.0
Medication: Aspirin	1.3	1.6	4.8	-0.1	0.4	-2.2
Leg fat mass (left)	1.3	5.2	10.6	1.7	-1.5	3.2
Time employed in main current job	1.2	1.4	2.4	-0.5	1.2	-1.5
Medication: Cholesterol lowering	1.2	1.8	2.9	1.0	1.2	-1.7
Ever highly irritable/argumentative for 2 days	1.2	1.5	3.6	-0.7	-0.5	1.9
Headache pain in last month	1.2	2.1	5.8	2.4	0.5	0.5
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	4.7	2.2	0.4	-1.4
Qualifications: College or University degree	1.2	3.9	9.2	-3.0	0.9	-1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	3.9	-0.5	0.1	-2.0
Whole body fat mass	1.2	5.2	11.0	1.2	-1.8	3.3
Ever had prostate specific antigen (PSA) test	1.2	1.4	3.2	-1.8	-0.6	-0.7
Triglycerides	1.1	1.8	5.3	-2.3	0.4	0.0
Hearing difficulty/problems: Yes	1.1	1.7	2.5	-1.3	-1.6	1.0
Diabetes (father)	1.1	1.4	4.0	0.4	0.0	2.0
Age when periods started (menarche)	1.1	2.6	6.4	-0.9	0.8	-2.5
Stomach or abdominal pain in last month	1.1	1.4	3.9	0.5	-2.0	-0.2
Medication: Levothyroxine sodium	1.1	1.8	5.1	2.3	-0.1	-0.6
Peak expiratory flow (PEF)	1.1	2.5	7.3	0.2	2.7	0.5
Gout (self-reported)	1.1	1.4	2.1	0.6	-1.4	1.4
Alcohol intake frequency.	1.1	2.5	6.5	0.8	-0.5	2.5
Medication: Aspirin	1.1	1.5	4.1	0.1	0.6	-2.0
Qualifications: nursing, teaching	1.1	1.7	4.3	-0.9	-2.1	-0.3
Fasting Glucose	1.0	1.2	2.3	-1.5	-1.1	0.0
Lung FEV1/FVC ratio	1.0	4.8	13.2	-0.2	3.6	1.1
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	2.7	1.6	-0.2	0.7
Current tobacco smoking	1.0	1.6	2.7	-0.1	-1.6	1.4
Trunk fat mass	1.0	4.3	9.9	0.7	-1.6	3.1
Neuroticism score	1.0	2.0	5.7	2.4	-0.6	-0.1
Father’s age at death	1.0	1.3	2.9	0.8	1.7	-0.7
Length of working week for main job	1.0	1.1	2.2	1.1	-0.0	1.5
Wheeze or whistling in the chest in last year	1.0	1.8	3.5	1.2	-1.9	-0.5
Number of full sisters	1.0	1.2	2.8	0.9	-1.7	0.3
Suffer from ‘nerves’	1.0	1.6	3.2	1.8	0.6	1.1
Smoking status: Current	1.0	1.6	2.5	0.1	-1.6	1.5
Miserableness	1.0	1.8	2.1	1.4	-1.4	-1.1
Pain type(s) experienced in last month: Hip pain	1.0	1.2	2.7	1.6	-0.7	0.7
Medication: Paracetamol	1.0	1.5	2.6	1.4	-1.6	-0.1
Age at First Birth	0.9	1.3	3.9	0.3	2.0	0.0
Neuroticism (2016)	0.9	1.3	3.6	1.9	-0.5	0.0
Type 2 Diabetes (T2D) (2012)	0.9	1.0	2.7	-0.6	-1.6	0.0
Diabetes (self-reported)	0.9	1.4	2.9	-1.1	-1.7	-0.5
Qualifications: A levels/AS levels or equivalent	0.9	2.1	5.2	-0.9	-2.3	-0.3
Tense / ‘highly strung’	0.9	1.4	2.7	1.2	-0.0	-1.6
Loud music exposure frequency	0.9	1.0	2.7	-1.6	0.4	-0.4
Medication: Ventolin 100micrograms inhaler	0.9	1.1	2.5	0.0	-1.6	0.9
Medication for pain relief, constipation, heartburn	0.9	1.5	4.0	-0.6	-0.6	2.0
Chest pain or discomfort	0.9	1.3	2.1	1.3	0.1	-1.4
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.4	-1.5	0.3	-0.9
Average weekly champagne plus white wine intake	0.9	1.3	2.8	-0.8	-0.7	-1.7
Ever smoked	0.9	1.7	3.3	0.9	0.9	-1.8
Pain experienced in last month	0.9	1.6	4.3	-0.6	2.1	0.1
Irritable Bowel Disease (IBD)	0.8	1.9	4.8	0.1	-0.8	-2.2
Heel T-Score	0.8	6.0	11.8	3.4	0.8	2.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	2.2	0.6	-1.5	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.7	4.8	2.2	-0.3	-0.5
Waist circumference	0.8	3.0	7.2	0.9	-0.9	2.7
Exposure to tobacco smoke at home	0.8	0.9	1.8	1.3	0.8	-0.5
Chronic bronchitis/emphysema (mother)	0.8	1.0	2.5	-1.6	-0.6	-0.0
Medication: Ibuprofen	0.8	0.9	2.7	-0.0	-1.6	-0.1
Guilty feelings	0.8	1.3	2.3	1.5	-0.8	-0.9
High cholesterol (Self-reported)	0.8	1.5	2.5	0.6	1.6	-1.2
Risk taking	0.8	1.2	1.8	1.3	-0.1	-1.3
Supplements: Calcium	0.8	0.8	2.4	0.0	1.6	-0.2
Worry (Nagel 2018)	0.7	1.5	4.3	2.1	-0.1	-0.2
Ovarian Cancer	0.7	0.9	2.2	-0.7	0.4	-1.5
Height	0.7	13.1	36.5	-6.0	0.7	1.5
Hypothyroidism (self reported)	0.7	1.5	3.1	1.8	0.1	-1.2
Chronotype (morning person)	0.7	1.6	2.1	-1.5	-1.4	0.8
Hair Pigment	0.7	20.5	46.8	3.3	6.8	1.9
Supplements: Zinc	0.7	0.7	2.0	0.0	0.4	1.4
Past tobacco smoking	0.7	1.3	2.4	-1.6	-0.9	0.8
Had other major operations	0.7	0.9	2.5	0.3	0.1	1.6
Alcohol intake versus 10 years previously	0.7	1.0	2.8	-0.1	-0.3	1.7
Noisy workplace	0.7	0.9	2.3	-1.5	0.5	-0.2
Lung cancer (father)	0.7	0.8	2.4	-0.2	1.6	-0.2
Standing height	0.7	6.8	16.9	-4.1	0.3	1.9
Angina (self-reported)	0.7	0.9	1.9	-0.7	-0.6	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	1.3	-1.1	-0.6	-1.0
Osteoporosis (self-reported)	0.7	0.8	1.3	-0.6	0.9	-1.1
Wears glasses or contact lenses	0.7	0.8	1.2	-0.1	-1.1	-1.1
Supplements: Fish oil (including cod liver oil)	0.7	1.0	2.6	-0.6	1.6	0.0
Average weekly beer plus cider intake	0.7	0.9	2.0	-0.3	-0.9	-1.4
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	1.1	1.0	1.1	-0.7
Body Mass Index (BMI) (2010)	0.6	0.8	1.7	1.3	-0.8	0.0
Blood Red Count	0.6	5.7	14.7	0.2	3.8	1.6
Angina	0.6	0.8	1.6	-0.8	-0.4	-1.3
Medication for hormone replacement therapy	0.6	0.7	0.8	-0.7	0.9	-0.8
Taking other prescription medications	0.6	1.0	2.0	0.2	1.4	-1.0
Hair/balding pattern: Pattern 3	0.6	1.0	1.6	0.8	-0.7	1.3
Depression (self-reported)	0.6	0.8	1.2	0.5	-0.9	1.1
Medication: Lansoprazole	0.6	0.6	1.6	-0.5	0.1	-1.3
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	2.0	0.7	-1.4	0.5
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	1.7	0.6	0.5	1.3
Leg fat percentage (right)	0.6	2.2	4.5	2.1	-1.1	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.4	1.2	0.8	-0.5
Diabetes diagnosed by doctor	0.6	0.9	2.0	-1.4	-0.8	-0.5
Friendships satisfaction	0.6	0.8	1.3	-1.1	1.0	-0.2
Medication for cholesterol	0.6	0.9	2.3	-0.5	-1.5	0.2
Ever taken oral contraceptive pill	0.6	0.7	1.4	0.3	1.2	0.7
Age started oral contraceptive pill	0.6	0.8	1.6	1.3	-0.2	0.8
Commuting to job workplace: Cycle	0.6	0.7	2.1	-0.1	1.4	0.0
Neuroticism (Nagel 2018)	0.5	1.1	3.0	1.7	-0.3	0.3
Alzheimer’s Disease (including proxy)	0.5	0.7	1.1	-0.7	1.1	-0.7
HbA1C	0.5	0.6	1.7	1.3	0.1	0.0
Primary Biliary Cirrhosis	0.5	0.7	1.7	-0.7	-1.3	0.0
Blood Eosinophil Count	0.5	4.1	6.5	-1.8	2.5	-1.7
Blood Platelet Count	0.5	6.3	18.7	-0.2	0.4	-4.3
Neuroticism	0.5	1.1	2.8	1.7	-0.5	-0.5
Ever had hysterectomy (womb removed)	0.5	0.5	1.0	0.1	0.8	1.0
Pack years adult smoking proportion	0.5	0.7	1.9	-0.3	0.4	1.4
Supplements: Glucosamine	0.5	0.6	1.4	-0.1	0.6	1.2
Qualifications: None of the above	0.5	1.0	2.6	1.6	0.2	0.6
Medication: Ramipril	0.5	0.6	1.1	0.2	-0.9	-1.0
Number of live births	0.5	0.7	1.7	-0.4	-1.3	-0.5
Medication: Amlodipine	0.5	0.8	2.2	1.5	0.2	-0.1
Body fat percentage	0.5	1.9	2.6	1.2	-1.3	1.6
Neck or shoulder pain in last month	0.5	0.8	1.8	0.7	-1.4	-0.1
Medication: Omeprazole	0.5	0.6	1.4	0.4	1.2	-0.3
Comparative height size at age 10	0.5	2.8	4.5	-2.1	0.6	1.9
Hypertension (Self-reported)	0.5	1.3	2.8	0.7	1.7	-0.8
Loneliness, isolation	0.5	0.7	1.2	1.0	-0.3	-1.1
Number of self-reported non-cancer illnesses	0.5	0.9	2.6	0.0	1.6	-0.1
Leg fat percentage (left)	0.5	2.0	4.2	2.0	-0.8	1.0
Diastolic blood pressure, automated reading	0.5	1.4	3.8	0.2	1.9	0.6
Depression (Nagel 2018)	0.4	0.6	0.9	0.1	-1.0	-0.9
Alzheimer’s Disease (in mother)	0.4	0.5	1.3	-0.3	-0.3	-1.1
Major Depression (MDD)	0.4	0.5	1.1	1.1	-0.5	0.0
Reaction Time	0.4	0.7	1.5	0.5	-1.2	0.7
Verbal and Numeric Reasoning (VNR)	0.4	1.0	1.9	0.1	1.4	1.0
Relative age of first facial hair	0.4	0.8	2.1	0.6	-0.1	1.4
Ever used hormone-replacement therapy (HRT)	0.4	0.5	0.6	0.8	-0.7	-0.7
Medication: Metformin	0.4	0.5	1.2	-0.5	-1.1	0.2
Trunk fat percentage	0.4	1.7	3.1	0.6	-1.2	1.8
Average weekly fortified wine intake	0.4	0.5	0.8	-0.9	0.7	0.4
Relative age voice broke	0.4	0.6	0.8	0.5	-0.8	0.9
Alcohol usually taken with meals	0.4	0.6	1.0	-0.4	1.0	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.6	0.1	-0.5	-1.3
Pain all over the body in last month	0.4	0.4	1.2	1.1	-0.0	0.3
Pulse rate	0.4	0.7	1.5	0.7	1.2	0.0
Blood clot in the leg (DVT)	0.4	0.5	0.7	0.8	0.8	-0.4
Number of full brothers	0.4	0.5	0.9	0.6	0.3	1.0
Worry too long after embarrassment	0.4	0.7	1.0	1.0	-0.3	1.0
Migraine (self-reported)	0.4	0.4	0.5	0.7	-0.7	-0.5
Pulse rate, automated reading	0.4	1.2	3.0	0.9	1.7	0.0
Leg pain on walking	0.4	0.4	0.8	0.7	-0.9	-0.2
Illnesses of siblings: Diabetes	0.4	0.5	0.8	0.5	-0.8	0.9
Commuting to job workplace: Walk	0.4	0.4	0.8	0.9	0.5	-0.6
Eye problems/disorders: Cataract	0.4	0.5	1.0	-0.5	1.0	-0.5
Mother’s age at death	0.4	0.5	1.1	1.1	0.4	0.5
Medication: Bendroflumethiazide	0.4	0.7	1.9	0.2	1.4	-0.1
Number of operations (self-reported)	0.4	0.6	1.1	-1.0	-0.1	-0.8
Myopia	0.4	0.6	1.8	0.3	0.2	-1.3
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.1	0.6	1.0	-0.2
Pack years of smoking	0.4	0.6	1.4	-0.3	0.6	1.2
Bipolar Disorder (2018)	0.3	0.5	1.4	1.2	0.5	0.0
Ulcerative Colitis (UC)	0.3	0.5	0.7	-0.7	-0.8	-0.5
Respiratory disease	0.3	0.7	1.6	0.6	1.3	0.1
Hand grip strength (left)	0.3	0.8	2.0	0.1	1.4	0.6
Number of treatments/medications taken	0.3	0.6	1.4	0.2	0.6	-1.2
Sensitivity / hurt feelings	0.3	0.6	0.9	1.0	0.8	0.4
Severe depression (siblings)	0.3	0.3	0.7	0.5	-0.2	0.8
Maternal smoking around birth	0.3	0.4	1.1	-0.1	0.5	-1.1
Fed-up feelings	0.3	0.6	1.0	0.6	-0.6	1.0
High blood pressure	0.3	0.7	1.6	0.5	1.3	-0.6
Hayfever, allergic rhinitis or eczema	0.3	0.7	2.1	-1.4	0.2	-0.2
Medication: Atenolol	0.3	0.4	0.5	0.5	0.7	0.6
Sitting height	0.3	2.1	3.9	-0.3	1.5	2.0
Chronic bronchitis/emphysema (father)	0.3	0.4	0.9	-0.4	-0.3	1.0
Had menopause	0.3	0.4	1.0	-1.0	0.4	0.0
Allergy	0.3	0.8	1.4	0.7	-1.2	0.7
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.6	0.4	-0.6	0.8
Illnesses of siblings	0.3	0.4	1.0	0.1	-1.0	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.6	-0.5	-0.4	-0.8
Health satisfaction	0.3	0.3	0.8	0.3	0.4	-0.9
Emphysema/chronic bronchitis	0.3	0.4	0.9	0.5	0.9	0.2
Medication: Allopurinol	0.3	0.5	1.0	-0.1	-0.6	1.0
Overall health rating	0.3	0.5	1.0	0.7	-1.0	0.4
Long-standing illness, disability or infirmity	0.3	0.5	0.7	0.8	-0.5	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	0.5	0.5	-0.7	0.7
Hearing aid user	0.3	0.4	0.8	0.9	-0.3	-0.6
Financial situation satisfaction	0.3	0.4	0.8	0.9	0.1	-0.6
Medication: Blood pressure	0.3	0.6	1.1	1.0	0.6	-0.6
Alcohol drinker status: Previous	0.3	0.3	0.5	-0.7	-0.7	0.2
Bipolar Disorder or Schizophrenia	0.2	0.6	1.5	1.2	0.4	0.0
Depressed Affect (Nagel 2018)	0.2	0.5	1.2	0.5	-1.1	0.1
Schizophrenia vs Biploar Disorder	0.2	0.2	0.7	0.8	-0.1	0.0
Mean Putamen Volume	0.2	0.2	0.6	-0.0	-0.7	0.0
HDL Cholesterol	0.2	0.4	1.2	0.0	1.1	0.0
Rheumatoid Arthritis	0.2	0.3	0.8	-0.9	-0.4	0.0
Schizophrenia (2014)	0.2	0.4	1.0	1.0	-0.5	0.0
Smoking Status	0.2	0.6	1.2	1.1	-0.2	0.7
Average weekly spirits intake	0.2	0.2	0.5	-0.2	-0.7	-0.3
Number of incorrect matches in round	0.2	0.3	0.8	0.2	0.9	-0.3
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.5	-0.2	0.5	0.7
Heart attack	0.2	0.3	0.7	-0.1	-0.2	-0.8
Fluid intelligence score	0.2	0.5	1.3	-0.4	1.2	0.2
Happiness	0.2	0.3	0.6	-0.5	-0.0	-0.8
Asthma	0.2	0.4	1.3	0.1	0.0	-1.1
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.5	-0.4	0.0	-0.7
Illnesses of mother	0.2	0.3	0.4	0.3	-0.6	0.6
Medication: Paracetamol	0.2	0.3	0.5	0.7	-0.6	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.5	0.5	0.1	0.7
Age at first live birth	0.2	0.4	0.8	-0.2	0.9	-0.7
Mean time to correctly identify matches	0.2	0.4	0.6	-0.5	-0.6	0.8
Had major operations	0.2	0.2	0.4	-0.3	0.6	-0.4
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.3	0.6	-0.3	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.3	-0.6	-0.2	0.4
Back pain experienced in last month	0.2	0.3	0.5	-0.6	-0.1	-0.7
Asthma (self-reported)	0.2	0.4	1.1	0.3	0.2	-1.1
Medication: Lisinopril	0.2	0.3	0.3	0.6	-0.4	-0.5
Irritability	0.2	0.3	0.9	0.9	-0.0	0.1
Fractured/broken bones in last 5 years	0.2	0.2	0.4	0.7	0.3	-0.5
Vascular/heart problems diagnosed by doctor	0.2	0.6	0.8	-0.6	-0.9	0.9
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.7	-0.2	0.0	-0.8
Heart disease (siblings)	0.2	0.2	0.6	0.2	-0.8	0.3
Crohns Disease (2012)	0.1	0.1	0.3	-0.6	0.3	0.0
LDL Cholesterol	0.1	0.2	0.4	0.6	0.5	0.0
Allergy or Eczema	0.1	0.2	0.3	-0.6	0.3	0.5
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.6	-0.7	-0.4	-0.1
Tanning	0.1	1.2	3.0	-0.1	-1.7	-0.8
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.2	0.1	0.4	-0.4
Systolic blood pressure, automated reading	0.1	0.1	0.3	0.1	0.5	-0.4
Hand grip strength (right)	0.1	0.2	0.5	-0.3	0.3	0.7
Townsend deprivation index at recruitment	0.1	0.2	0.5	-0.1	-0.1	0.7
Qualifications: CSEs or equivalent	0.1	0.1	0.2	0.3	0.5	0.3
Pulse wave Arterial Stiffness index	0.1	0.2	0.4	-0.1	0.3	-0.6
Pulse wave reflection index	0.1	0.1	0.2	-0.0	0.2	0.5
Exposure to tobacco smoke outside home	0.1	0.2	0.2	0.4	0.4	0.4
Pulse wave peak to peak time	0.1	0.2	0.4	-0.4	-0.1	0.6
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.4	-0.3	0.1	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.4	-0.6	0.5	0.3
Intelligence (Savage-Jansen 2018)	0.0	0.0	0.1	-0.0	-0.1	0.2
Schizophrenia (2018)	0.0	0.1	0.2	0.4	0.1	0.0
Bipolar Disorder (2011)	0.0	0.0	0.1	0.0	0.3	0.0
Diabetes (mother)	0.0	0.1	0.1	-0.4	0.2	-0.1
High blood pressure (mother)	0.0	0.0	0.1	0.1	0.3	0.0
Financial difficulties in last 2 years	0.0	0.0	0.0	-0.1	0.2	-0.1
Medication: Simvastatin	0.0	0.1	0.1	-0.1	0.2	-0.4
Number of children fathered	0.0	0.1	0.1	0.3	-0.1	-0.2
Shortness of breath walking on level ground	0.0	0.0	0.1	0.3	0.2	-0.0
Medication: Seretide 50 evohaler	0.0	0.0	0.0	0.0	0.1	-0.0
Illnesses of father: Heart disease	0.0	0.1	0.2	0.4	-0.1	0.2
Tinnitus: Yes, now most or all of the time	0.0	0.0	0.1	0.2	-0.1	-0.0
Cholesterol lowering medication	0.0	0.1	0.1	-0.1	0.2	-0.3

Hub : Genes

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