Hub : Genes

RAVER2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0710	0.0230	1.4e-04	0.063	0.034	0.058	0.041	0.060	3.8e-08	5.1e-05	1.3e-07	8.5e-06	8.6e-08
2	GTEx	Brain Caudate basal ganglia	0.3460	0.0920	6.7e-04	-0.009	NA	-0.010	NA	-0.007	7.0e-01	NA	8.5e-01	NA	5.5e-01
3	GTEx	Thyroid	0.1960	0.0520	3.7e-05	0.053	NA	0.027	NA	0.028	6.4e-05	NA	3.5e-03	NA	2.9e-03
4	METSIM	Adipose	0.0329	0.0195	3.7e-02	-0.001	0.003	0.001	0.004	-0.001	6.3e-01	9.4e-02	2.1e-01	6.5e-02	5.8e-01
5	ROSMAP	Brain Pre-frontal Cortex	0.3344	0.0403	0.0e+00	0.325	0.369	0.369	0.380	0.368	8.5e-43	8.6e-50	6.8e-50	1.0e-51	1.2e-49
6	TCGA	Esophageal Carcinoma	0.1520	0.0750	3.4e-03	0.062	0.062	0.046	NA	0.069	5.0e-03	5.1e-03	1.4e-02	NA	3.3e-03
7	TCGA	Brain Lower Grade Glioma	0.0441	0.0196	8.3e-06	0.025	0.053	0.045	NA	0.042	6.1e-04	1.0e-06	7.7e-06	NA	1.4e-05
8	TCGA	Prostate Adenocarcinoma	0.0363	0.0201	1.8e-03	0.047	0.026	0.021	NA	0.038	9.7e-06	9.5e-04	2.3e-03	NA	6.4e-05
9	TCGA	Thyroid Carcinoma	0.1150	0.0380	3.2e-12	0.079	0.133	0.140	NA	0.139	3.8e-08	6.2e-13	1.7e-13	NA	2.1e-13

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.6	1.0	3.3	0.4	0.6	-0.9	0.7	0.4	1.3	1.8	1.2	-0.5
Bipolar Disorder or Schizophrenia	0.5	1.3	3.2	-1.6	1.8	-1.0	-1.6	-1.2	0.5	0.4	-0.5	-0.7
Depressed Affect (Nagel 2018)	0.3	0.7	2.0	0.2	1.4	-0.6	0.9	1.3	0.5	0.5	0.2	-0.6
Depression (Nagel 2018)	0.3	0.4	1.5	0.2	0.3	-1.2	0.1	0.4	1.1	0.5	0.0	-0.7
Intelligence (Savage-Jansen 2018)	2.6	8.0	16.7	3.5	-1.1	1.6	3.5	3.3	-0.4	3.2	4.1	2.2
Neuroticism (Nagel 2018)	0.6	1.4	3.4	1.0	0.5	-1.7	0.9	0.6	1.9	1.3	0.4	-1.2
Schizophrenia (2018)	1.2	2.5	6.6	-2.3	1.8	-0.5	-2.6	-1.8	-0.4	-0.9	-1.6	-0.5
Schizophrenia vs Biploar Disorder	1.6	2.1	4.9	-2.2	-1.0	0.1	-1.2	-2.0	-0.4	-2.0	-1.6	-1.1
Worry (Nagel 2018)	0.3	0.6	1.8	0.7	-0.1	-1.3	0.5	-0.4	1.2	0.5	-0.2	-0.9
Alzheimer’s Disease (in mother)	2.1	2.5	7.8	0.2	-0.2	-2.7	-0.1	-1.4	2.8	-0.2	-0.8	-2.1
Alzheimer’s Disease (in father)	0.6	0.7	1.7	0.7	-1.0	1.3	0.6	0.9	-0.5	0.3	1.1	0.3
Alzheimer’s Disease (including proxy)	0.8	1.2	4.2	0.8	-0.9	-1.4	0.2	-0.4	2.0	0.0	-0.0	-1.7
Crohns Disease (2017)	0.8	1.7	5.0	0.8	-0.1	2.2	0.8	0.2	-1.8	1.1	0.6	2.2
Irritable Bowel Disease (IBD)	1.4	3.3	10.2	-1.1	-0.5	3.2	-0.2	-1.7	-2.8	-0.2	-1.1	2.4
Ulcerative Colitis (UC)	1.9	3.5	7.4	-2.3	-0.1	2.7	-0.7	-2.2	-2.6	-1.0	-1.8	1.5
Major Depression (MDD)	1.3	1.6	4.1	1.3	0.9	-2.0	-0.1	0.5	2.0	1.4	0.7	-0.9
Reaction Time	0.4	0.7	4.2	-0.0	2.1	-0.5	-0.1	0.3	0.8	-0.5	-0.4	-0.7
Verbal and Numeric Reasoning (VNR)	1.8	4.2	9.2	2.4	-0.9	2.0	2.4	2.0	-0.7	2.0	3.0	1.8
Breast Cancer	1.4	3.5	8.1	1.6	-1.8	2.3	2.9	1.5	-0.8	1.2	1.9	2.0
Ovarian Cancer	0.2	0.3	1.1	0.3	-1.1	-0.6	0.5	0.0	0.8	0.3	-0.0	-0.5
Prostate Cancer	0.1	0.2	0.5	0.2	-0.4	0.1	0.0	0.4	-0.7	-0.2	-0.5	0.5
Age at First Birth	0.6	0.8	2.2	-1.5	0.6	0.2	-0.5	-0.6	-0.6	-1.5	-1.3	-0.1
Bipolar Disorder (2011)	0.3	0.3	1.0	0.8	0.3	-0.4	-0.4	0.2	0.5	1.0	0.8	0.1
Body Mass Index (BMI) (2010)	0.2	0.3	0.8	-0.6	0.9	-0.2	0.2	0.2	0.2	-0.7	-0.3	-0.8
Coronary Artery Disease (CAD)	0.7	0.8	2.9	-0.5	1.7	-1.1	-0.5	0.2	0.8	1.1	-0.3	-0.8
Crohns Disease (2012)	1.2	1.9	6.1	0.2	-1.3	2.5	-0.4	-0.4	-2.1	-0.2	0.5	2.1
Mean Putamen Volume	1.2	1.4	3.9	-1.0	0.6	-2.0	-1.0	-0.4	1.4	0.0	-0.5	-2.0
Fasting Glucose	0.3	0.3	0.9	-0.2	0.1	-0.1	0.5	0.8	0.7	-1.0	0.1	-0.6
HbA1C	1.0	1.2	3.8	-0.4	1.1	1.9	-0.3	0.1	-1.8	-0.3	-0.1	1.3
HDL Cholesterol	0.4	0.6	2.2	0.0	-0.1	-1.4	-0.4	0.1	1.5	0.7	-0.1	-0.9
LDL Cholesterol	0.6	1.0	3.5	-1.0	-1.6	0.3	0.6	-1.9	-0.0	-0.9	-0.8	-0.2
Lupus	0.5	0.8	2.1	-1.4	0.3	0.0	-0.3	-1.1	-0.3	-1.2	-1.4	-0.2
Neuroticism (2016)	2.0	2.8	5.4	2.3	0.9	-1.9	0.3	1.9	2.0	2.2	1.7	-0.6
Primary Biliary Cirrhosis	0.4	0.6	2.0	-0.2	-0.9	-0.5	0.2	-0.7	0.9	-1.0	-0.3	-1.4
Rheumatoid Arthritis	1.0	1.4	7.1	1.4	-2.7	0.8	0.2	0.4	-0.4	0.9	1.0	0.7
Schizophrenia (2014)	1.7	3.7	9.0	-2.7	2.2	-1.0	-3.0	-1.9	0.2	-1.1	-2.0	-1.4
Triglycerides	0.2	0.3	0.8	-0.1	-0.8	0.7	0.5	-0.4	-0.9	-0.5	-0.4	0.4
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.7	0.4	0.3	-0.2	0.9	-0.0	0.5	0.5	0.9	0.1
Ulcerative Colitis	3.2	4.7	10.9	-2.1	-0.5	2.8	-1.6	-3.3	-2.6	-1.8	-2.0	1.7
Blood Eosinophil Count	1.6	12.5	41.9	-1.0	-6.5	-1.1	-1.7	-5.8	3.6	-2.0	-1.6	-3.5
Blood Platelet Count	1.2	14.3	41.9	4.2	1.6	-1.3	2.3	5.5	1.7	6.5	5.0	0.6
Blood Red Count	0.2	1.8	4.2	2.0	-0.6	-1.7	1.2	0.1	1.6	1.9	0.8	-0.1
Blood White Count	0.7	5.2	11.8	-3.1	3.4	-0.7	-3.2	-2.7	-0.4	0.0	-2.5	-0.7
Heel T-Score	0.9	7.4	21.2	1.0	-2.2	4.6	2.6	1.9	-3.4	0.6	2.1	3.7
BMI	0.6	3.4	6.1	2.1	2.2	0.6	2.4	2.5	-0.5	2.4	1.4	0.9
Height	0.1	1.6	4.4	0.4	-1.3	2.1	0.4	1.1	-2.0	-1.2	0.5	1.0
Waist Hip Ratio (WHR)	0.3	1.3	2.9	1.2	-0.4	0.8	0.8	1.7	-1.2	1.0	1.0	1.6
Systolic Blood Pressure	0.2	0.8	2.9	-0.5	0.8	-0.7	-1.7	-1.1	0.2	-0.4	-1.0	-0.9
Smoking Status	0.5	1.2	3.4	-1.5	0.6	-0.5	-1.8	-0.7	0.1	-0.9	-1.7	-0.9
Allergy or Eczema	1.2	3.2	9.4	0.0	-1.9	-3.0	-0.9	0.3	3.1	-0.1	-0.4	-2.4
Cardiovascular Disease	0.3	1.1	4.0	0.8	2.0	0.9	0.7	1.3	-0.9	0.4	0.7	0.8
Hypothyroidism (self reported)	2.7	6.2	23.7	2.6	-4.9	-1.8	1.4	-1.0	3.2	1.9	1.9	-1.2
Respiratory disease	1.3	2.9	9.8	0.4	-3.1	-2.0	-0.2	-1.1	2.5	-0.3	-0.6	-2.1
Type 2 Diabetes (T2D) (2018)	0.5	0.9	6.9	0.2	2.6	-0.0	-0.3	0.4	0.2	0.7	0.3	-0.3
Lung FEV1/FVC ratio	0.1	0.6	2.5	0.6	0.9	-0.7	-0.5	1.6	0.1	0.9	0.2	-0.0
Lung FVC	0.2	0.8	5.6	-0.0	0.1	-0.5	-2.4	-0.0	0.5	-0.4	-0.5	-0.6
Neuroticism	1.0	2.5	7.6	0.8	0.5	-2.8	0.4	-0.2	2.7	0.7	-0.3	-2.4
Chronotype (morning person)	1.3	3.0	7.2	0.7	-0.1	2.4	2.6	1.0	-2.0	0.8	1.2	2.7
Hair Pigment	0.1	2.5	6.9	0.2	1.8	1.7	2.3	2.6	-1.6	0.4	0.9	1.0
Tanning	0.1	1.1	3.5	0.6	0.1	-1.9	-1.0	-0.2	1.6	1.2	0.2	-0.8
Hand grip strength (left)	0.1	0.4	1.1	-0.1	-0.9	0.8	-1.1	0.4	-0.7	0.1	0.5	0.1
Number of treatments/medications taken	0.5	0.9	3.8	0.7	-0.2	0.0	2.0	1.0	0.7	0.9	1.1	0.4
Average weekly spirits intake	0.2	0.3	0.9	0.3	-0.4	-0.0	1.0	0.6	0.2	0.8	0.5	0.0
Sensitivity / hurt feelings	0.1	0.1	0.6	0.0	0.8	0.2	0.1	0.1	0.3	0.1	0.2	-0.5
Frequency of depressed mood in last 2 weeks	0.7	1.0	3.0	0.9	-0.6	-1.7	0.3	0.0	1.6	0.7	0.0	-1.1
Hearing difficulty/problems: Yes	0.6	0.9	3.7	-0.5	0.3	-0.6	-1.9	-1.1	0.3	0.1	-1.3	-0.4
Relative age of first facial hair	0.1	0.2	0.7	0.5	-0.9	0.2	-0.1	0.0	0.3	-0.1	0.5	0.2
Other serious medical condition/disability diagnosed by doctor	0.7	1.0	2.8	0.7	-0.6	0.3	1.7	1.6	0.6	-0.3	1.4	-0.0
Ever used hormone-replacement therapy (HRT)	0.8	1.1	2.4	1.3	-0.8	0.5	0.5	0.5	-0.3	1.5	1.3	1.5
Ever had hysterectomy (womb removed)	0.5	0.6	1.8	0.6	-1.3	-0.8	-1.3	-0.5	0.4	0.6	-0.3	-0.2
Systolic blood pressure, automated reading	0.2	0.6	1.4	0.3	0.7	-1.1	-1.2	-0.1	1.0	0.7	-0.2	-0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	2.4	0.1	1.6	0.3	0.1	0.0	-0.2	0.6	0.2	0.3
Angina	0.3	0.4	1.7	0.1	1.2	0.6	0.5	0.0	-0.2	-1.3	-0.3	0.0
Medication for hormone replacement therapy	1.5	1.7	4.5	1.8	-1.2	-0.9	0.7	0.9	1.4	2.1	1.4	-0.1
Vitamin and mineral supplements	0.3	0.4	1.6	0.9	-0.1	0.2	1.2	0.6	0.4	0.0	0.7	0.0
Supplements: Zinc	1.4	1.5	2.6	0.5	-0.5	1.3	1.2	1.3	-1.0	1.3	1.6	1.6
Medication: Co-codamol	0.7	0.8	2.7	0.6	-1.6	0.5	0.9	1.0	0.1	1.1	1.0	0.2
Medication: Metformin	0.4	0.6	4.2	0.1	2.1	0.6	0.6	0.4	-0.4	0.3	0.2	0.3
Diabetes (father)	0.3	0.4	0.9	0.7	0.9	-0.7	-0.6	0.4	0.3	0.9	-0.2	-0.2
Diabetes (mother)	0.3	0.3	1.0	0.1	-0.1	-0.6	-0.1	-0.6	1.0	0.4	0.1	-1.0
Severe depression (siblings)	0.6	0.6	1.3	-1.1	0.4	-0.1	-1.0	-1.1	-0.3	-0.9	-1.1	0.3
Pack years adult smoking proportion	1.4	2.1	4.4	1.6	-1.3	0.3	2.0	2.1	-0.4	1.3	1.9	0.9
Impedance of leg (right)	0.9	4.6	9.7	-1.6	-0.6	-2.7	-3.1	-3.1	2.0	-0.6	-1.4	-2.3
Leg fat-free mass (left)	1.1	5.6	12.7	2.3	0.5	2.6	3.1	3.6	-2.2	1.4	2.1	2.1
Trunk fat percentage	0.2	0.9	3.7	0.8	1.9	-0.7	-0.2	-0.1	0.3	1.6	0.1	0.3
Hand grip strength (right)	0.1	0.3	1.5	-0.0	-1.2	0.5	-0.3	0.4	-0.1	-0.3	0.7	-0.1
Townsend deprivation index at recruitment	0.4	0.6	2.3	1.1	-1.5	-0.7	-0.6	0.1	0.6	0.7	0.2	-0.4
Current tobacco smoking	0.3	0.4	1.0	-0.9	0.4	1.0	-0.3	0.4	-0.9	-0.9	-0.4	0.3
Average weekly fortified wine intake	0.4	0.5	1.4	0.3	0.8	0.0	0.4	0.8	0.7	0.8	1.2	0.0
Maternal smoking around birth	0.7	1.0	2.4	0.9	1.5	-0.9	0.8	0.9	0.8	1.6	0.7	-0.1
Fed-up feelings	0.6	1.1	2.7	-1.0	-0.0	-1.4	-0.1	-0.7	1.3	-0.6	-1.4	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.0	0.3	-0.3	-1.0	-0.9	-0.2	0.6	0.9	-0.3	-0.5
Relative age voice broke	0.2	0.3	0.7	-0.8	0.3	-0.3	-0.1	-0.3	0.5	-0.5	-0.5	-0.8
Taking other prescription medications	0.8	1.2	2.1	1.5	-0.8	-0.5	1.4	0.9	1.4	1.1	1.3	-0.3
Age when periods started (menarche)	0.6	1.6	7.6	-0.2	-2.8	1.0	0.2	-1.9	-0.5	-1.2	-0.3	0.1
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	3.7	0.2	-1.9	-0.4	0.5	-0.1	0.9	-0.3	-0.3	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	2.0	4.5	6.3	2.4	-1.3	2.2	2.3	2.1	-1.6	1.6	2.5	2.5
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	2.3	-0.1	0.7	-1.5	-1.1	-1.0	1.0	1.3	0.1	-0.5
Qualifications: CSEs or equivalent	0.6	0.8	1.7	-0.9	-0.3	0.9	-0.2	-1.3	-0.9	-1.1	-1.1	0.4
Serious illness, injury or assault to yourself	1.0	1.3	3.9	1.1	-0.1	-1.8	-0.2	0.0	2.0	0.5	0.3	-1.7
High blood pressure	0.5	1.3	3.7	0.8	1.9	0.9	1.2	0.6	-1.1	1.1	0.9	1.4
Hayfever, allergic rhinitis or eczema	1.0	2.2	6.4	-0.3	-1.3	-2.5	-1.1	0.2	2.4	-0.3	-0.7	-2.1
Multivitamins +/- minerals	0.5	0.7	1.4	-0.7	0.0	1.0	-1.2	-1.1	-1.1	-0.2	-0.7	0.7
Stomach or abdominal pain in last month	0.3	0.4	2.3	0.5	-1.5	-0.1	0.1	0.7	-0.2	0.4	0.6	0.1
Supplements: Glucosamine	0.6	0.7	2.3	0.3	0.2	0.8	0.8	-0.4	-1.0	1.0	0.7	1.5
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.4	0.5	0.9	-1.6	-0.2	0.1	1.2	0.4	0.6	-0.8
Medication: Atenolol	1.9	2.4	6.2	2.1	-0.5	-0.2	2.0	1.2	1.1	2.0	2.5	-0.1
Medication: Levothyroxine sodium	1.6	2.7	8.8	1.1	-2.2	-2.1	0.2	-1.2	3.0	0.3	0.3	-1.8
Sitting height	0.4	2.5	7.1	0.2	0.7	2.7	1.1	1.6	-2.5	-0.6	0.9	1.9
Chronic bronchitis/emphysema (father)	1.0	1.2	3.4	0.9	-1.8	-0.9	1.3	-0.2	1.5	0.7	0.7	-1.0
High blood pressure (mother)	0.3	0.4	2.2	-0.2	0.9	0.1	1.5	0.4	0.4	0.2	0.5	-0.5
Body mass index (BMI)	0.5	1.9	5.0	1.6	1.5	0.2	1.8	1.8	0.1	2.2	1.1	0.6
Impedance of leg (left)	1.0	4.8	12.8	-1.8	0.1	-2.7	-3.6	-3.0	1.8	-0.6	-1.7	-2.1
Leg predicted mass (left)	1.1	5.8	12.8	2.4	0.5	2.6	3.1	3.6	-2.2	1.4	2.2	2.2
Trunk fat mass	0.3	1.3	3.8	1.3	2.0	0.2	0.7	1.0	-0.3	1.8	0.8	0.8
Waist circumference	0.9	3.2	6.6	1.9	1.7	1.0	2.1	2.6	-1.0	2.3	1.6	1.5
Number of incorrect matches in round	0.2	0.3	1.3	-0.5	0.3	0.4	-1.1	-0.2	-0.5	-0.3	-0.3	0.3
Past tobacco smoking	0.3	0.5	1.3	0.5	-0.1	0.3	1.1	1.1	-0.1	0.4	1.1	-0.3
Alcohol usually taken with meals	0.9	1.5	6.6	-2.1	0.1	1.1	0.3	-0.6	-0.5	-2.6	-0.8	-0.3
Nervous feelings	0.4	0.7	2.5	0.3	0.8	-1.6	0.2	0.2	1.3	0.5	-0.4	-1.1
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	2.6	0.9	-0.1	-0.9	0.4	1.6	0.8	0.7	0.5	-0.6
Hearing difficulty/problems with background noise	0.3	0.4	1.0	-0.7	-0.4	0.9	-0.5	-0.5	-0.8	-0.6	-1.0	0.1
Hair/balding pattern: Pattern 2	0.3	0.4	1.3	-0.2	-0.1	0.8	-0.7	0.3	-1.1	-0.2	-0.3	0.7
Had menopause	0.3	0.3	0.9	0.1	0.2	-1.0	-0.6	-0.8	0.9	-0.0	-0.1	-0.3
Had other major operations	0.8	1.0	2.5	1.2	1.0	0.5	0.9	1.6	-0.2	0.8	1.1	1.0
Forced vital capacity (FVC)	0.3	1.3	4.2	0.3	-0.2	1.7	-1.6	0.7	-2.0	-0.0	-0.0	1.2
Heel bone mineral density (BMD) T-score, automated (right)	2.4	5.4	9.9	3.1	-0.7	1.9	2.3	2.7	-1.7	2.0	2.8	2.8
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	4.5	-0.7	-0.8	2.1	0.7	-1.1	-1.6	-0.6	-0.1	1.0
Qualifications: None of the above	2.6	5.5	10.8	-2.5	1.8	-1.9	-3.3	-2.7	0.9	-1.6	-3.1	-2.3
Financial difficulties in last 2 years	1.8	2.4	5.4	2.3	-1.3	1.1	1.0	1.9	-0.9	1.3	1.7	1.7
Mouth/teeth dental problems	0.7	1.1	3.2	-0.6	0.2	1.7	0.4	0.5	-1.8	-1.2	0.2	1.2
Heart attack	5.5	7.0	19.0	1.3	-0.9	4.4	3.2	1.4	-3.6	0.1	1.7	3.7
Allergy	1.4	3.2	9.1	-0.7	3.0	2.6	0.7	0.0	-2.8	-0.2	0.3	2.0
Pain all over the body in last month	3.0	3.2	9.1	-2.4	1.1	-1.4	-2.4	-1.7	0.6	-0.9	-3.0	-1.1
Diabetes (self-reported)	1.0	1.6	7.1	-0.1	2.7	-1.4	-1.1	-0.4	1.4	0.7	-0.2	-1.1
Hayfever/allergic rhinitis (self-reported)	2.0	2.6	8.2	1.2	-0.8	-2.9	-1.3	0.6	2.7	0.5	0.1	-2.0
Medication: Ramipril	1.2	1.6	3.4	0.8	0.9	1.9	0.8	1.2	-1.8	0.6	0.8	1.8
Medication: Simvastatin	0.4	0.6	1.4	0.5	1.2	-0.6	-0.1	0.7	1.0	1.0	0.9	-0.3
Fluid intelligence score	2.3	4.8	9.0	2.6	-1.2	1.7	2.9	1.8	-0.5	2.4	3.0	2.2
Illnesses of siblings	0.9	1.2	4.6	0.6	-2.1	0.8	1.7	1.0	0.3	0.2	1.2	0.1
Neuroticism score	0.6	1.3	3.8	0.7	0.6	-1.9	0.5	0.7	2.0	0.4	-0.1	-1.5
Weight	0.7	3.2	7.1	1.9	1.8	1.0	2.2	2.7	-0.8	2.1	1.7	1.2
Impedance of arm (right)	1.0	4.8	9.9	-1.2	0.5	-2.8	-3.1	-3.1	2.0	-1.1	-1.8	-2.2
Arm fat percentage (right)	0.3	1.1	4.8	0.8	2.2	-1.1	-0.0	0.3	0.8	1.7	-0.1	-0.3
Trunk fat-free mass	1.0	6.0	16.2	2.0	0.3	2.8	3.1	4.0	-2.3	1.3	2.5	1.9
Hip circumference	0.4	1.9	4.0	1.0	2.0	1.0	1.2	1.7	-0.9	1.8	1.2	1.0
Time employed in main current job	2.0	2.3	10.8	-1.9	3.3	-0.7	-1.4	-0.1	0.8	-0.3	-1.1	-1.4
Alcohol intake versus 10 years previously	0.3	0.5	2.2	-0.6	0.2	0.8	0.6	-0.1	-0.8	-1.5	-0.7	0.2
Father’s age at death	0.1	0.2	0.8	0.0	-0.3	0.6	0.9	-0.2	0.2	-0.6	0.4	0.0
Worrier / anxious feelings	0.3	0.6	1.3	-0.1	0.9	-1.1	0.9	0.5	1.0	0.0	-0.2	-1.2
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.9	2.3	1.4	-0.0	-0.7	0.6	1.1	0.4	1.5	1.1	-0.1
Falls in the last year	1.5	2.1	4.8	1.0	1.1	1.4	2.2	1.4	-1.4	1.4	1.3	1.4
Hair/balding pattern: Pattern 3	0.6	0.8	2.0	-0.8	0.4	-1.3	0.2	-0.9	1.0	-0.9	-0.7	-1.4
Number of live births	1.0	1.4	3.2	-0.9	1.5	-1.8	-1.7	-0.1	0.8	0.0	-1.1	-1.1
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	2.7	0.6	-0.1	1.2	-1.4	0.5	-1.6	0.5	-0.0	1.1
Pulse rate	0.3	0.6	1.6	0.6	1.0	-0.6	0.7	0.9	0.5	1.3	0.2	-0.2
Happiness	0.5	0.6	1.3	0.6	0.2	1.1	0.9	0.8	-0.7	0.6	0.8	1.0
Noisy workplace	0.8	1.0	3.4	0.5	0.6	-1.5	-1.9	0.6	0.7	1.1	0.2	-0.5
Qualifications: A levels/AS levels or equivalent	0.6	1.4	2.3	1.2	-1.0	1.4	1.5	1.0	-0.9	0.3	1.4	1.5
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	3.2	-0.8	-0.5	0.3	-1.0	-1.6	0.5	-1.8	-0.9	-0.4
Mouth/teeth dental problems: Dentures	1.1	1.9	5.5	1.8	-0.8	0.6	1.3	1.0	0.2	2.3	1.8	1.0
Asthma	1.6	3.2	9.5	0.5	-3.1	-2.3	0.1	-1.3	2.5	-0.9	-1.1	-1.9
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	3.8	-0.3	-0.3	1.9	1.5	1.0	-1.6	0.3	0.3	1.9
Medication: Cholesterol lowering	0.4	0.6	2.2	-0.2	0.7	1.5	0.8	0.6	-0.7	-0.5	0.8	0.4
Depression (self-reported)	0.4	0.5	2.8	0.8	-1.7	0.5	0.9	0.4	-0.3	-0.1	0.0	0.1
Medication: Lansoprazole	4.8	5.5	14.8	2.9	0.9	-2.7	1.5	2.5	2.2	3.9	2.0	-0.7
Prospective memory result	0.4	0.5	2.0	-0.2	0.6	-1.4	-0.4	0.0	0.8	0.5	-0.1	-1.0
Lung cancer (father)	1.1	1.3	4.6	-0.5	0.5	1.4	-1.3	0.3	-2.1	0.5	-0.2	1.7
Illnesses of mother	0.4	0.4	2.4	-0.4	-0.4	-0.4	-1.5	-0.2	-0.1	-0.6	-0.8	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.8	4.8	0.9	0.4	-0.3	-2.2	0.3	-0.5	0.9	-0.2	-0.0
Pulse wave Arterial Stiffness index	1.1	1.3	2.8	0.0	1.7	1.5	-0.5	1.2	-1.5	0.1	0.2	1.6
Impedance of arm (left)	0.8	3.6	8.6	-1.3	0.3	-2.2	-2.9	-2.9	1.4	-1.3	-1.7	-1.6
Arm fat mass (right)	0.3	1.3	3.5	1.2	1.9	0.4	1.0	1.4	-0.4	1.6	0.6	0.8
Trunk predicted mass	1.0	5.8	16.0	2.0	0.4	2.6	3.1	4.0	-2.2	1.4	2.4	1.8
Standing height	0.3	2.7	6.2	0.8	0.5	2.3	0.9	2.3	-2.5	0.0	1.6	1.8
Length of working week for main job	0.9	1.0	2.9	1.2	0.1	-0.2	0.8	1.2	0.4	1.7	1.5	0.3
Exposure to tobacco smoke at home	0.7	0.7	2.7	0.8	0.3	-1.0	0.2	0.2	1.0	1.6	0.9	-0.6
Breastfed as a baby	0.2	0.3	1.6	0.0	-1.3	-0.2	0.1	0.6	0.5	0.3	0.4	-0.0
Tense / ‘highly strung’	0.1	0.2	0.9	0.2	-0.9	-0.4	0.3	-0.4	0.1	-0.2	-0.5	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.2	0.8	-0.4	-0.0	-0.2	-0.0	-0.8	0.0	-0.9	-0.4	-0.6
Hair/balding pattern: Pattern 4	0.2	0.4	1.5	0.1	-1.2	0.5	-0.3	-0.8	-0.3	-0.5	-0.5	0.6
Birth weight of first child	0.4	0.7	1.6	-0.4	0.9	1.2	0.6	-0.8	-0.9	0.6	0.5	1.3
Peak expiratory flow (PEF)	0.8	1.8	5.8	0.8	-1.0	1.8	-0.1	0.7	-2.2	0.5	0.3	2.4
Pulse wave reflection index	1.1	1.3	3.3	-0.7	0.7	1.8	-1.1	0.0	-1.8	-0.9	-0.5	1.5
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.0	-0.1	0.3	-0.8	-1.0	-0.5	0.6	0.1	-0.4	-0.6
Loud music exposure frequency	3.1	3.4	7.6	-1.7	-1.2	-0.5	-1.8	-2.6	0.5	-2.8	-2.4	-1.6
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	3.0	1.3	-0.3	0.9	1.7	1.6	-0.3	0.8	1.4	0.9
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.1	-0.2	0.4	-1.0	-0.5	-0.9	0.6	-0.1	-0.9	-0.8
Blood clot in the leg (DVT)	0.8	1.0	2.2	1.3	-1.3	0.2	1.1	0.8	0.1	1.0	1.5	0.5
Medication: Paracetamol	0.2	0.3	1.2	-0.7	0.7	-0.3	-1.1	0.1	0.1	-0.2	-0.9	0.2
Headache pain in last month	3.5	6.0	9.5	2.4	-2.1	2.7	3.1	2.5	-2.2	1.5	2.7	2.6
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.0	0.3	-0.9	-1.0	-0.7	-0.2	0.7	0.3	-0.1	-0.5
Glaucoma (self-reported)	1.3	1.6	3.4	1.1	0.2	-1.7	-0.1	1.5	1.8	1.3	1.2	-1.0
Gout (self-reported)	1.2	1.7	3.0	1.5	1.7	0.4	1.7	1.7	-0.2	1.3	1.2	0.9
Hypothyroidism/myxoedema (self-reported)	1.5	3.0	11.2	2.0	-3.4	-1.0	1.2	-0.9	2.2	1.1	1.2	-0.8
Medication: Amlodipine	0.9	1.2	2.7	-1.5	0.8	-0.8	-1.6	-1.0	0.2	-1.0	-1.3	-0.9
Medication: Ventolin 100micrograms inhaler	0.9	1.1	2.1	-0.8	-0.6	-1.1	-0.9	-1.1	1.0	-1.2	-1.1	-1.5
Birth weight	0.1	0.2	1.1	0.1	1.0	0.3	0.1	0.1	-0.3	-0.3	-0.2	0.3
Chronic bronchitis/emphysema (mother)	0.5	0.6	4.6	0.1	-2.1	0.6	-0.3	0.0	-0.4	0.2	0.2	0.3
High blood pressure (siblings)	0.2	0.4	1.2	-0.2	-0.1	0.4	-1.1	-0.5	-0.8	-0.3	-0.4	0.8
Forced vital capacity (FVC), Best measure	0.2	0.8	3.3	1.1	-0.3	0.5	-1.8	0.8	-1.0	0.5	0.2	0.4
Body fat percentage	0.3	1.3	5.1	0.6	2.2	-1.3	-0.3	-0.0	0.9	1.8	-0.1	-0.3
Leg fat percentage (right)	0.5	1.7	5.6	1.0	2.0	-1.6	-0.1	0.2	1.3	2.4	0.3	-0.7
Arm fat-free mass (right)	1.1	5.6	13.2	1.9	0.5	2.7	2.9	3.6	-2.3	1.4	2.3	2.3
Exposure to tobacco smoke outside home	0.2	0.3	1.0	0.1	-0.3	0.8	1.0	0.3	-0.3	-0.2	0.3	0.6
Comparative body size at age 10	0.6	1.5	3.5	1.9	0.2	1.0	0.9	1.9	-0.6	1.4	1.4	1.0
Number of full brothers	0.5	0.6	1.6	-0.2	0.2	0.5	-0.8	-1.3	-1.0	0.5	-0.9	0.8
Worry too long after embarrassment	1.5	2.5	5.9	1.9	-0.6	-1.1	1.9	1.2	1.5	2.4	1.9	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	2.4	0.6	-1.5	0.1	0.4	-0.2	0.0	-0.4	0.2	0.1
Wheeze or whistling in the chest in last year	0.1	0.1	0.4	-0.1	-0.7	-0.2	0.5	0.2	0.1	0.5	-0.2	-0.4
Number of children fathered	0.6	0.7	2.4	-1.0	0.1	1.5	0.4	-0.1	-1.3	-0.8	0.2	0.8
Reason for reducing amount of alcohol drunk: Health precaution	3.6	4.2	7.7	-1.7	0.1	-1.6	-2.4	-2.5	1.7	-2.3	-2.1	-2.8
Age at first live birth	0.6	1.1	4.6	-0.9	-0.8	1.4	0.7	-0.7	-0.7	-2.1	-0.3	0.1
Pulse wave peak to peak time	1.1	1.3	3.6	-0.3	-1.9	-1.2	0.4	-1.4	1.3	-0.6	-0.4	-1.6
Health satisfaction	1.3	1.6	7.0	1.1	-0.1	0.7	1.0	2.6	-0.4	1.1	1.6	1.0
Shortness of breath walking on level ground	0.6	0.8	3.1	0.7	0.6	-0.2	0.7	1.3	0.1	1.8	0.9	0.1
Qualifications: College or University degree	0.3	1.0	2.5	1.3	-1.1	0.2	1.0	1.0	0.3	1.1	1.6	0.4
Eye problems/disorders: None of the above	0.4	0.5	1.4	-0.3	0.3	1.2	-0.4	0.9	-1.1	-0.4	0.1	0.9
Mouth/teeth dental problems: Loose teeth	0.8	0.9	2.6	-1.5	-0.6	0.0	-0.3	-1.3	-0.1	-1.1	-1.6	-0.1
Emphysema/chronic bronchitis	0.9	1.0	3.5	0.8	-1.9	-1.0	0.3	-0.1	1.5	1.1	0.5	-0.5
Medication for pain relief, constipation, heartburn	0.2	0.4	1.2	0.3	0.1	-0.9	-0.6	-0.7	0.5	0.3	0.2	-1.1
Neck or shoulder pain in last month	0.6	0.8	2.8	0.8	0.5	0.9	1.7	0.8	-0.8	0.6	0.7	0.6
Medication: Blood pressure	0.6	1.0	3.8	0.2	0.3	1.5	2.0	0.6	-1.0	-0.0	0.4	1.0
Angina (self-reported)	0.5	0.6	2.2	0.2	1.1	1.0	0.9	0.2	-0.4	-1.5	-0.1	0.2
Migraine (self-reported)	1.2	1.5	4.0	0.6	-0.9	1.7	-0.0	0.6	-1.4	0.9	1.5	2.0
Medication: Ibuprofen	0.7	0.9	2.7	-0.7	-0.3	1.6	0.4	0.5	-1.4	-0.1	-0.2	1.5
Medication: Allopurinol	1.8	2.4	3.9	1.4	1.5	1.2	1.2	1.9	-1.1	1.9	1.5	2.0
Medication: Omeprazole	0.2	0.3	0.8	-0.1	-0.6	0.5	-0.2	0.9	-0.7	-0.1	0.1	0.8
Medication: Seretide 50 evohaler	0.4	0.4	2.7	0.1	-0.3	-0.2	1.6	0.9	0.3	0.0	-0.0	-0.2
Mean time to correctly identify matches	0.7	1.3	6.7	0.3	2.6	-1.2	-0.2	0.5	1.6	-0.2	-0.2	-0.9
Heart disease (mother)	0.7	0.8	3.4	1.0	0.4	-0.0	1.8	0.4	0.4	1.2	1.1	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	0.8	-0.4	-0.6	0.4	-0.1	-0.6	-0.8	-0.2	-0.2	0.9
Whole body fat mass	0.3	1.4	3.5	1.4	1.9	0.0	1.0	1.3	-0.2	1.9	0.8	0.6
Leg fat mass (right)	0.4	1.4	3.8	1.3	1.7	0.1	1.3	1.3	-0.0	2.0	0.8	0.5
Arm predicted mass (right)	1.5	7.6	17.6	2.4	0.4	2.9	3.5	4.2	-2.4	1.9	2.9	2.6
Pulse rate, automated reading	0.2	0.7	2.9	0.7	0.8	-0.9	-0.7	0.2	0.1	1.7	-0.7	0.7
Alcohol intake frequency.	0.2	0.5	2.0	1.1	0.1	0.3	1.4	0.6	-0.3	0.6	0.4	0.5
Comparative height size at age 10	0.1	0.5	1.8	-0.1	1.2	-0.8	-1.4	-0.1	0.3	0.2	-0.3	-0.6
Number of full sisters	0.5	0.6	1.5	1.2	-1.1	-0.6	-0.3	0.6	0.8	0.8	0.8	-0.2
Suffer from ‘nerves’	1.2	2.0	4.7	1.4	0.1	-2.1	0.6	0.9	2.2	1.2	0.4	-1.8
Overall health rating	0.9	2.0	4.9	1.5	1.1	0.6	2.2	2.1	-0.5	1.4	1.1	1.1
Chest pain or discomfort	0.2	0.3	0.7	0.5	0.4	-0.7	0.8	-0.7	0.4	0.5	-0.5	-0.1
Had major operations	0.5	0.6	2.9	0.1	0.4	1.1	1.7	0.0	-0.9	0.1	0.2	0.5
Age at last live birth	0.9	1.2	2.0	-1.1	1.0	-0.9	-1.1	-1.2	0.6	-1.4	-1.2	-1.2
Family relationship satisfaction	0.3	0.4	1.4	-0.8	-1.2	0.9	0.1	0.5	-0.3	-0.8	0.2	0.0
Leg pain on walking	0.3	0.4	1.0	1.0	0.7	-0.0	0.8	1.0	0.1	0.3	0.8	0.3
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.7	3.6	0.9	1.2	0.9	0.9	1.9	-0.7	1.9	1.3	1.6
Commuting to job workplace: Car/motor vehicle	3.9	4.4	10.6	2.8	-0.1	-0.6	1.7	2.6	1.0	3.2	3.2	-0.1
Illness, injury, bereavement, stress in last 2 years	1.6	1.9	5.6	-1.9	0.9	1.8	0.4	-0.2	-2.4	-0.9	-1.1	1.4
Medication: Aspirin	0.5	0.6	2.6	-0.1	0.7	1.6	0.9	0.3	-0.8	-0.4	0.5	0.9
Supplements: Vitamin C	1.0	1.2	3.5	-0.0	0.7	1.0	-0.1	0.8	-1.9	1.2	0.4	1.8
Knee pain experienced in last month	0.7	1.0	3.1	1.4	0.1	0.1	1.8	0.1	0.4	1.6	1.2	0.4
Hypertension (Self-reported)	0.5	1.3	3.6	0.8	1.9	0.8	1.0	0.7	-1.1	1.2	0.9	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.8	-0.3	0.7	-1.4	-0.6	-0.4	0.8	0.8	-0.3	-0.4
Illnesses of father: Heart disease	0.5	0.7	2.8	-0.2	1.7	-0.6	-0.5	-0.9	0.3	-0.9	-0.9	-0.6
Illnesses of siblings: Diabetes	1.0	1.2	7.5	-0.0	2.7	-0.8	-0.6	-0.6	0.5	0.8	-0.3	-1.1
Smoking status: Previous	0.2	0.3	0.8	0.5	-0.3	-0.9	-0.1	-0.3	0.8	0.9	-0.0	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	2.0	1.2	0.6	0.9	-0.3	1.4	-1.1	0.3	1.3	0.6
Whole body fat-free mass	1.1	6.4	16.3	2.2	0.5	2.7	3.3	4.0	-2.3	1.5	2.5	2.1
Leg fat-free mass (right)	1.1	6.1	13.5	2.2	0.8	2.9	3.0	3.7	-2.5	1.4	2.1	2.4
Arm fat percentage (left)	0.2	1.0	4.1	0.9	2.0	-0.7	0.2	0.5	0.5	1.7	0.1	0.1
Average weekly red wine intake	0.5	0.8	2.6	-1.6	0.2	0.9	0.4	-0.5	-0.7	-1.4	-0.7	0.2
Handedness (chirality/laterality): Left-handed	1.6	1.9	6.9	0.4	-2.6	1.4	2.5	0.5	-0.4	-0.5	0.7	0.5
Mood swings	0.5	0.8	2.2	-0.8	1.5	-1.2	0.2	0.3	1.2	-0.1	-0.3	-1.3
Loneliness, isolation	1.0	1.4	2.9	1.7	-1.2	1.3	0.1	1.6	-1.1	-0.0	0.6	1.4
Long-standing illness, disability or infirmity	0.6	0.9	2.3	1.5	0.0	-0.8	0.7	0.3	1.1	1.5	0.8	-0.3
Ever had bowel cancer screening	0.0	0.0	0.1	-0.2	0.3	-0.2	-0.2	-0.1	-0.1	0.1	-0.3	0.2
Diabetes diagnosed by doctor	0.5	0.8	6.3	-0.1	2.5	-0.4	-0.4	-0.0	0.6	0.5	-0.0	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	4.4	0.5	-2.1	-0.4	-0.1	-0.3	0.5	-0.8	-0.0	-0.4
Friendships satisfaction	0.5	0.6	2.3	-0.5	-1.5	0.9	-0.2	-0.6	-0.6	-1.1	-0.5	0.3
Qualifications: nursing, teaching	1.7	2.7	5.9	2.2	-1.4	0.3	2.4	1.6	0.4	1.9	2.1	0.7
Commuting to job workplace: Walk	1.2	1.3	2.8	-1.7	0.9	-0.1	-1.6	-0.9	-0.1	-1.2	-1.6	-0.7
Eye problems/disorders: Cataract	0.4	0.4	1.2	0.9	-0.9	-0.1	0.5	-0.8	0.2	1.1	0.5	0.1
Mouth/teeth dental problems: Mouth ulcers	3.1	5.0	13.3	-1.3	-0.1	-3.0	-3.7	-2.0	2.4	-0.2	-1.9	-2.7
Medication for cholesterol	0.8	1.2	3.5	-1.4	-0.1	1.1	-0.8	-0.4	-1.5	-1.9	-1.0	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.2	0.9	-0.8	-1.1	-0.2	-0.2	0.5	0.6	-0.2	0.4
Back pain experienced in last month	0.6	0.9	2.3	1.3	-0.2	0.5	1.1	0.6	-0.9	1.5	0.9	0.7
Mineral and other dietary supplements	0.6	0.8	1.8	0.9	-0.7	-1.0	-1.1	1.3	0.8	0.5	0.6	-0.7
Breast cancer (self-reported)	1.9	2.3	18.1	-0.8	4.3	-0.8	-0.6	0.5	0.4	-0.3	-0.6	-0.5
Asthma (self-reported)	1.5	3.0	11.8	0.5	-3.4	-2.0	0.2	-1.2	2.2	-0.9	-0.9	-1.7
Osteoporosis (self-reported)	0.6	0.8	2.0	0.8	-1.4	0.9	1.1	0.7	-0.7	-0.8	0.6	0.7
Osteoarthritis (self-reported)	3.1	4.0	7.0	1.7	-1.6	2.0	2.6	2.2	-1.1	1.6	2.4	2.2
Medication: Aspirin	0.4	0.5	1.9	-0.3	0.7	1.4	1.1	0.4	-0.4	-0.4	0.5	0.6
Medication: Gliclazide	0.6	0.7	2.2	0.3	-0.5	1.5	-0.2	0.2	-1.4	-0.1	0.3	1.3
Illnesses of father: None of the above (group 1)	0.5	0.6	2.0	0.7	-0.5	0.2	0.2	1.4	-0.3	1.2	1.0	0.6
Smoking status: Current	0.5	0.8	1.8	-1.2	0.8	1.0	-0.8	0.0	-1.0	-1.3	-0.9	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	2.6	0.3	0.7	-0.5	-1.6	0.1	0.4	0.4	-0.4	-0.7
Whole body water mass	1.1	6.1	15.7	2.2	0.6	2.7	3.1	4.0	-2.3	1.5	2.4	2.1
Leg predicted mass (right)	1.1	6.0	13.5	2.3	0.7	2.8	3.0	3.7	-2.4	1.4	2.1	2.4
Arm fat mass (left)	0.4	1.6	3.6	1.4	1.8	0.4	1.0	1.6	-0.5	1.9	0.8	1.0
Number of self-reported non-cancer illnesses	1.2	2.1	5.1	2.3	-1.3	-1.2	1.0	1.0	1.8	1.6	1.7	-0.3
Average weekly champagne plus white wine intake	0.4	0.6	2.7	-0.8	0.3	1.0	0.3	-0.4	-0.8	-1.7	-0.4	-0.0
Miserableness	1.0	1.8	7.6	-0.3	2.8	-1.4	0.4	0.9	1.3	0.5	0.1	-1.9
Guilty feelings	0.1	0.2	0.9	0.9	-0.4	0.1	0.2	0.5	0.5	-0.2	0.3	0.1
Wears glasses or contact lenses	0.2	0.2	0.8	0.3	-0.8	0.2	-0.3	0.5	-0.2	-0.1	-0.0	0.9
Ever taken oral contraceptive pill	0.3	0.3	0.7	0.5	-0.3	-0.4	0.4	0.4	0.6	0.4	0.7	-0.8
Hearing aid user	0.8	1.0	2.2	0.8	-0.0	-1.2	0.9	0.7	1.5	1.0	1.2	-0.7
Mother’s age at death	0.9	1.2	3.2	-1.8	-1.1	0.4	-0.4	-1.5	-0.3	-1.1	-1.5	0.0
Financial situation satisfaction	1.8	2.2	5.7	0.7	0.4	1.8	2.4	2.3	-1.1	-0.2	1.3	1.3
Tinnitus: Yes, now most or all of the time	1.0	1.1	2.4	1.6	-1.1	-1.3	-1.5	-0.2	1.2	0.3	0.2	-1.1
Commuting to job workplace: Public transport	1.4	1.7	6.9	-0.5	-2.1	0.7	0.7	-0.8	-0.1	-2.6	-1.3	0.3
Eye problems/disorders: Glaucoma	1.5	1.8	3.5	1.4	0.5	-1.7	0.1	1.4	1.8	1.9	1.5	-0.8
Medication: Blood pressure	0.2	0.4	2.1	0.4	1.4	-0.3	0.0	-0.3	0.0	0.8	0.1	0.3
Pain type(s) experienced in last month: Hip pain	1.8	2.3	5.1	1.2	-1.0	1.9	2.2	0.2	-1.3	1.3	1.3	2.1
Supplements: Fish oil (including cod liver oil)	0.2	0.3	2.0	-0.0	-0.4	-0.0	1.4	-0.7	0.5	0.2	-0.0	-0.0
High cholesterol (Self-reported)	0.4	0.8	6.4	0.4	2.5	-0.2	0.0	0.6	0.1	0.4	0.2	0.1
Medication: Bendroflumethiazide	2.3	3.5	6.7	2.6	-0.8	-1.9	1.9	-0.2	2.5	2.3	1.9	-1.2
Medication: Paracetamol	0.4	0.6	2.0	-1.0	0.2	-0.5	-1.2	-0.3	0.3	-0.3	-1.4	-0.1
Medication: Lisinopril	1.7	2.2	4.0	1.4	1.8	-0.7	2.0	1.6	0.5	2.0	1.8	-0.1
Medication: Atorvastatin	1.8	2.2	6.6	1.4	-0.3	1.6	2.6	1.6	-1.2	0.7	1.4	1.4
Illnesses of father: High blood pressure	0.1	0.1	0.2	-0.1	0.2	-0.5	-0.2	-0.0	0.4	-0.2	-0.3	-0.3
Alcohol drinker status: Never	0.3	0.4	2.3	0.9	0.1	-0.4	-0.2	-0.1	0.4	1.5	0.3	-0.2
Ever smoked	0.9	1.5	3.8	-1.3	-0.2	0.1	-1.5	-1.9	-0.4	-1.4	-2.0	0.3
Basal metabolic rate	1.0	5.3	13.4	2.1	0.8	2.4	2.9	3.7	-2.0	1.6	2.2	1.9
Leg fat percentage (left)	0.4	1.5	5.6	0.5	2.4	-1.4	-0.5	-0.0	1.0	2.0	-0.1	-0.6
Arm fat-free mass (left)	1.0	5.2	12.7	2.1	1.0	2.2	2.9	3.6	-1.9	1.8	2.3	1.9
Number of operations (self-reported)	0.7	1.0	2.6	-0.2	0.4	1.4	1.2	-0.3	-1.6	-0.7	-0.6	1.6
Average weekly beer plus cider intake	0.7	1.0	3.5	1.2	-0.9	0.3	-0.3	1.9	-0.3	1.4	1.0	0.4
Irritability	1.0	1.7	5.8	0.3	0.2	-2.1	0.7	-0.5	2.4	0.9	-0.3	-1.9
Risk taking	1.6	2.3	5.3	2.3	-2.2	0.2	1.3	0.8	0.3	1.9	1.8	1.0
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.7	-0.6	-0.2	1.2	0.5	0.1	-1.6	-0.5	-0.2	0.8
Fractured/broken bones in last 5 years	0.8	1.1	3.0	0.7	-1.2	1.1	1.7	0.8	-0.6	0.8	1.1	0.9
Age started oral contraceptive pill	0.4	0.5	2.2	-0.5	-0.2	-0.6	-0.8	-1.5	0.8	-0.5	-0.6	-0.5
Diastolic blood pressure, automated reading	0.2	0.6	2.5	1.2	0.1	-0.8	0.1	0.3	0.5	1.6	0.5	0.3
Ever depressed for a whole week	1.9	2.3	5.1	-1.9	-0.4	1.5	-0.0	-2.1	-1.5	-2.3	-1.5	0.4
Unable to work because of sickness or disability	0.3	0.4	1.3	0.8	-0.6	-0.9	-0.0	0.0	0.8	0.3	-0.2	-1.1
Commuting to job workplace: Cycle	1.0	1.2	6.9	-0.9	-2.6	0.2	-0.2	-0.8	0.3	-1.0	-0.6	-0.7
Myopia	0.6	0.9	3.2	-0.2	-1.1	1.8	1.1	-0.3	-1.0	-0.5	0.2	0.9
Vascular/heart problems diagnosed by doctor	0.4	1.1	2.5	-0.9	-1.6	-0.6	-1.3	-0.6	0.7	-1.0	-1.0	-1.1
Cholesterol lowering medication	0.3	0.4	2.1	0.6	1.5	-0.5	-0.1	0.4	0.5	0.8	0.2	0.3
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.7	-0.3	-0.3	-0.4	-0.8	-0.1	-0.0	-0.2	-0.5	0.0
Pain experienced in last month	0.6	1.0	3.1	-0.7	0.3	-0.7	-1.8	-0.7	1.0	-1.4	-0.8	-0.8
Supplements: Calcium	1.1	1.2	2.6	1.1	-0.5	1.1	0.8	1.4	-0.8	0.9	1.6	1.4
Basal cell carcinoma (self-reported)	1.0	1.2	3.6	-0.5	-0.4	1.9	1.2	-0.3	-1.7	-1.2	0.1	1.1
Heart attack/myocardial infarction (self-reported)	5.3	6.8	18.5	1.4	-1.1	4.3	3.2	1.4	-3.4	-0.1	1.8	3.5
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	3.1	1.5	-1.4	0.4	1.4	0.9	-0.0	1.3	1.8	0.7
Heart disease (siblings)	0.5	0.6	2.4	1.6	0.6	0.0	1.0	0.3	-0.3	0.7	0.4	0.7
Alcohol drinker status: Previous	0.7	0.7	2.3	1.0	-1.5	-0.3	0.6	0.2	0.4	1.5	0.6	0.4
Pack years of smoking	1.1	1.6	3.7	1.2	-1.2	0.4	1.9	1.7	-0.4	1.1	1.6	1.0
Impedance of whole body	1.0	5.0	12.4	-1.4	0.1	-2.8	-3.5	-3.3	1.9	-0.9	-1.7	-2.0
Leg fat mass (left)	0.3	1.3	3.8	1.1	2.0	0.2	1.0	1.2	-0.3	1.8	0.6	0.6
Arm predicted mass (left)	1.1	5.8	14.7	2.3	0.8	2.2	3.1	3.8	-1.8	2.0	2.5	2.0