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chr7:138,028,165-140,572,110

Best TWAS P=1.9e-12 · Best GWAS P=2.55e-10 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	The Cancer Genome Atlas	Breast Invasive Carcinoma	JHDM1D	0.05	0.01	blup	58	0.01	5.9e-04	-5.1	-7.0	1.9e-12	-0.01	0.01	0.04	TRUE
9	The Cancer Genome Atlas	Prostate Adenocarcinoma	PARP12	0.06	0.04	lasso	2	0.04	1.3e-04	-6.2	-6.4	1.3e-10	0.04	0.01	0.98	TRUE
1	GTEx	Nerve Tibial	ZC3HAV1L	0.16	0.12	enet	7	0.08	3.6e-06	-5.9	-5.9	4.1e-09	-0.98	0.01	0.99	TRUE
10	The Cancer Genome Atlas	Thyroid Carcinoma	JHDM1D	0.14	0.01	blup	58	0.04	6.2e-05	3.3	-6.5	7.9e-11	-0.04	0.05	0.03	FALSE
11	The Cancer Genome Atlas	Thyroid Carcinoma	PARP12	0.14	0.11	enet	10	0.12	9.4e-12	-6.2	6.2	5.9e-10	-0.04	0.01	0.99	FALSE
5	The Cancer Genome Atlas	Lung Adenocarcinoma	PARP12	0.02	0.01	blup	68	0.01	2.4e-02	-6.3	6.1	1.3e-09	-0.04	0.01	0.94	FALSE
2	ROSMAP	Brain Pre-frontal Cortex	JHDM1D	0.14	0.07	bslmm	490	0.12	3.6e-15	2.5	-5.4	5.6e-08	-0.06	1.00	0.00	FALSE
4	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ZC3HAV1L	0.03	0.03	enet	4	0.02	4.2e-03	5.1	5.2	1.6e-07	0.96	0.02	0.94	FALSE
7	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ZC3HAV1	0.04	0.01	blup	76	0.02	2.4e-03	6.3	5.2	1.9e-07	0.70	0.01	0.80	FALSE
8	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ZC3HAV1L	0.02	0.01	blup	46	0.00	7.9e-02	4.6	5.2	2.3e-07	0.85	0.02	0.71	FALSE
6	The Cancer Genome Atlas	Lung Adenocarcinoma	ZC3HAV1	0.03	0.00	enet	5	0.01	2.8e-02	-5.9	5.1	2.8e-07	0.94	0.01	0.84	FALSE