[Hub]/) : Traits : Blood Platelet Count : ← →

chr17:55,730,637-58,739,670

Best TWAS P=4.41e-22 · Best GWAS P=3.9e-20 conditioned to 1.15e-12

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
14	YFS	Blood	DHX40	0.01	0.01	lasso	8	0.01	1.6e-03	-7.9	9.7	4.4e-22	-0.22	0.28	0.40	TRUE
1	GTEx	Adipose Visceral Omentum	SUPT4H1	0.10	0.04	lasso	6	0.04	3.7e-03	7.5	-7.6	2.7e-14	0.00	0.10	0.50	TRUE
19	The Cancer Genome Atlas	Prostate Adenocarcinoma	MPO	0.05	0.00	blup	46	0.01	2.0e-02	3.2	6.0	1.9e-09	-0.02	0.01	0.29	TRUE
8	GTEx	Nerve Tibial	RPS6KB1	0.05	0.01	lasso	4	0.00	1.6e-01	-7.5	8.9	3.6e-19	-0.13	0.07	0.04	FALSE
5	GTEx	Esophagus Mucosa	DHX40	0.14	0.10	lasso	7	0.07	3.1e-05	-8.6	-8.8	1.1e-18	0.18	0.19	0.80	FALSE
10	GTEx	Testis	DHX40	0.24	0.13	lasso	10	0.18	2.6e-08	-8.6	-8.6	7.1e-18	0.14	0.19	0.81	FALSE
11	GTEx	Thyroid	DHX40	0.07	0.04	lasso	7	0.03	1.7e-03	-8.6	-8.6	9.9e-18	0.14	0.19	0.43	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	DHX40	0.16	0.05	lasso	4	0.08	4.9e-05	-8.6	-7.7	2.0e-14	0.33	0.18	0.50	FALSE
2	GTEx	Cells Transformed fibroblasts	RPS6KB1	0.11	0.07	lasso	5	0.06	2.0e-05	-7.9	7.3	1.9e-13	0.06	0.53	0.12	FALSE
6	GTEx	Lung	DHX40	0.11	0.04	lasso	8	0.09	4.1e-07	-8.0	-7.2	7.3e-13	0.52	0.23	0.66	FALSE
13	NTR	Blood	MIR21	0.01	0.02	lasso	2	0.02	9.0e-06	-6.7	-6.6	3.7e-11	0.22	0.98	0.01	FALSE
7	GTEx	Muscle Skeletal	RP11-567L7.5	0.16	0.06	enet	12	0.06	1.8e-06	-4.0	-6.1	1.2e-09	0.30	0.95	0.02	FALSE
3	GTEx	Colon Sigmoid	RP11-567L7.5	0.14	0.06	lasso	4	0.10	1.6e-04	-6.5	-6.0	2.6e-09	0.25	0.15	0.04	FALSE
17	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	MPO	0.07	0.06	lasso	3	0.07	8.6e-04	6.7	6.0	2.6e-09	0.02	0.02	0.39	FALSE
12	GTEx	Thyroid	SUPT4H1	0.07	0.05	lasso	2	0.08	1.5e-06	5.3	-5.7	1.5e-08	-0.02	0.44	0.16	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	BZRAP1	0.05	0.00	blup	60	0.01	1.2e-02	4.1	5.6	1.7e-08	0.05	0.09	0.49	FALSE
15	YFS	Blood	RPS6KB1	0.01	0.01	blup	272	0.01	1.1e-03	-7.2	5.6	2.6e-08	0.19	0.25	0.06	FALSE
20	The Cancer Genome Atlas	Soft Tissue Sarcoma	CLTC	0.07	0.03	lasso	3	0.02	1.5e-02	-4.6	-5.3	8.9e-08	0.28	0.04	0.19	FALSE
4	GTEx	Colon Sigmoid	AC005702.4	0.21	0.22	enet	18	0.20	1.6e-07	-2.6	-5.3	1.4e-07	0.04	0.75	0.01	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MPO	0.06	0.01	blup	45	0.02	4.1e-03	6.7	5.2	2.6e-07	0.13	0.04	0.09	FALSE