Best TWAS P=3.84e-12 · Best GWAS P=2.85e-53 conditioned to 1.02e-32
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | RRP1 | 0.19 | 0.01 | enet | 31 | -0.01 | 9.1e-01 | 1.1 | -6.9 | 3.8e-12 | -0.36 | 0.07 | 0.24 | TRUE |
| 2 | GTEx | Esophagus Mucosa | RRP1 | 0.19 | 0.01 | lasso | 6 | 0.02 | 3.0e-02 | -5.2 | 5.5 | 3.1e-08 | 0.09 | 0.11 | 0.04 | TRUE |
| 3 | GTEx | Thyroid | PTTG1IP | 0.31 | 0.17 | lasso | 9 | 0.21 | 7.2e-16 | -4.5 | 5.2 | 1.5e-07 | 0.04 | 0.79 | 0.20 | TRUE |
| 4 | METSIM | Adipose | WDR4 | 0.06 | 0.02 | blup | 640 | 0.02 | 1.7e-03 | 1.5 | -6.8 | 1.3e-11 | -0.19 | 0.35 | 0.17 | TRUE |