Best TWAS P=1.07e-51 · Best GWAS P=3.13e-71 conditioned to 2.14e-20
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | PKDCC | 0.11 | 0.00 | enet | 35 | 0.03 | 2.2e-03 | 3.2 | 7.9 | 2.4e-15 | -0.51 | 0.02 | 0.77 | FALSE |
| 2 | GTEx | Heart Left Ventricle | PKDCC | 0.28 | 0.08 | lasso | 4 | 0.14 | 8.7e-08 | -17.3 | 15.1 | 1.1e-51 | -0.82 | 0.01 | 0.99 | TRUE |
| 3 | GTEx | Muscle Skeletal | EML4 | 0.13 | 0.03 | lasso | 5 | 0.04 | 1.1e-04 | 1.4 | 6.2 | 4.6e-10 | -0.40 | 0.32 | 0.53 | FALSE |
| 4 | GTEx | Nerve Tibial | ZFP36L2 | 0.06 | 0.00 | lasso | 8 | 0.01 | 3.5e-02 | 6.1 | -6.4 | 1.3e-10 | 0.03 | 0.24 | 0.11 | TRUE |