[Hub]/) : Traits : Hair Pigment : ← →

chr2:62,658,256-64,817,256

Best TWAS P=1.64e-12 · Best GWAS P=1.14e-11 conditioned to 0.194

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	MDH1	0.39	0.41	lasso	12	0.39	3.6e-34	5.2	5.2	1.9e-07	-0.52	0.99	0.01	FALSE
2	GTEx	Adipose Subcutaneous	WDPCP	0.23	0.29	lasso	19	0.29	4.6e-24	5.5	5.3	1.0e-07	-0.54	0.97	0.03	FALSE
3	GTEx	Adipose Visceral Omentum	WDPCP	0.09	0.05	lasso	7	0.06	2.8e-04	5.0	5.2	2.5e-07	-0.62	0.15	0.68	FALSE
4	GTEx	Artery Tibial	MDH1	0.06	0.06	lasso	2	0.04	4.2e-04	5.3	5.3	1.1e-07	-0.52	0.77	0.06	FALSE
5	GTEx	Brain Cerebellum	WDPCP	0.14	0.00	enet	12	0.00	3.1e-01	-6.8	6.4	2.0e-10	-0.92	0.02	0.89	FALSE
6	GTEx	Cells Transformed fibroblasts	WDPCP	0.14	0.08	enet	24	0.07	3.6e-06	5.0	6.3	2.9e-10	-0.60	0.37	0.56	FALSE
7	GTEx	Colon Sigmoid	WDPCP	0.15	0.05	lasso	4	0.03	3.0e-02	5.2	6.0	2.6e-09	-0.70	0.19	0.64	FALSE
8	GTEx	Esophagus Mucosa	WDPCP	0.06	0.03	lasso	3	0.04	1.7e-03	4.9	5.2	1.9e-07	-0.55	0.57	0.03	FALSE
9	GTEx	Lung	WDPCP	0.13	0.05	enet	29	0.09	1.2e-07	4.6	5.2	1.9e-07	-0.65	0.45	0.55	FALSE
10	GTEx	Nerve Tibial	UGP2	0.06	0.01	enet	12	0.02	8.7e-03	5.3	5.3	1.2e-07	-0.66	0.27	0.48	FALSE
11	GTEx	Pancreas	WDPCP	0.13	0.06	lasso	6	0.04	1.2e-02	5.1	5.4	8.0e-08	-0.51	0.52	0.08	FALSE
12	GTEx	Stomach	WDPCP	0.07	0.03	enet	17	0.03	1.1e-02	-6.8	7.1	1.6e-12	-0.87	0.02	0.92	TRUE
13	GTEx	Testis	WDPCP	0.17	0.08	enet	15	0.12	4.2e-06	5.1	5.5	2.8e-08	-0.64	0.42	0.52	FALSE
14	GTEx	Thyroid	WDPCP	0.07	0.03	lasso	6	0.06	2.1e-05	4.7	5.4	6.5e-08	-0.62	0.53	0.42	FALSE
15	GTEx	Whole Blood	WDPCP	0.05	0.04	lasso	2	0.03	5.5e-04	5.4	5.5	3.0e-08	-0.37	0.76	0.05	FALSE
16	METSIM	Adipose	MDH1	0.10	0.21	enet	32	0.20	1.5e-29	5.5	5.2	2.0e-07	-0.48	0.97	0.03	FALSE
17	METSIM	Adipose	UGP2	0.03	0.02	lasso	1	0.03	2.2e-05	5.3	5.3	1.3e-07	-0.52	0.97	0.02	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	AC074367.1	0.03	0.01	blup	241	0.01	9.9e-03	5.4	-6.0	2.3e-09	0.55	0.13	0.27	FALSE
19	YFS	Blood	MDH1	0.02	0.03	enet	9	0.02	2.3e-08	5.2	5.3	9.8e-08	-0.52	0.97	0.03	FALSE
20	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C2orf86	0.02	0.02	blup	141	0.02	4.9e-03	5.2	5.4	8.1e-08	-0.41	0.22	0.07	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	C2orf86	0.05	0.02	blup	141	0.04	2.1e-05	5.2	5.5	4.5e-08	-0.52	0.92	0.05	FALSE
22	The Cancer Genome Atlas	Soft Tissue Sarcoma	C2orf86	0.12	0.07	blup	141	0.08	2.7e-05	4.5	6.4	1.8e-10	-0.79	0.07	0.90	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	C2orf86	0.05	0.05	blup	141	0.06	1.1e-06	5.7	6.4	1.6e-10	-0.75	0.39	0.60	FALSE