[Hub]/) : Traits : Hair Pigment : ← →

chr2:69,422,629-71,228,388

Best TWAS P=8.3e-17 · Best GWAS P=1.74e-14 conditioned to 0.0989

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	PCYOX1	0.12	0.04	lasso	3	0.02	1.6e-02	6.5	6.5	9.9e-11	0.87	0.03	0.91	FALSE
2	GTEx	Artery Tibial	PCYOX1	0.22	0.18	lasso	4	0.17	1.3e-13	6.4	6.4	1.2e-10	0.86	0.94	0.06	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	FAM136A	0.31	0.12	lasso	7	0.16	5.6e-06	-6.0	-8.3	8.3e-17	-0.56	0.10	0.88	TRUE
4	GTEx	Cells EBV-transformed lymphocytes	SNRNP27	0.24	0.02	enet	16	0.02	6.2e-02	-5.1	-5.6	1.7e-08	-0.43	0.06	0.06	FALSE
5	GTEx	Cells Transformed fibroblasts	FAM136A	0.22	0.17	lasso	5	0.14	6.2e-11	6.5	-6.6	5.4e-11	-0.76	0.86	0.14	FALSE
6	GTEx	Colon Sigmoid	PCYOX1	0.19	0.00	enet	27	0.00	3.0e-01	-2.6	5.6	2.2e-08	0.63	0.02	0.74	FALSE
7	GTEx	Colon Transverse	PCYOX1	0.13	0.01	lasso	3	0.00	2.7e-01	5.6	6.5	9.1e-11	0.75	0.08	0.67	FALSE
8	GTEx	Esophagus Muscularis	PCYOX1	0.18	0.16	enet	14	0.15	1.9e-09	7.7	7.5	6.6e-14	0.94	0.00	1.00	FALSE
9	GTEx	Heart Left Ventricle	FAM136A	0.17	0.09	enet	22	0.09	2.0e-05	6.6	-5.9	4.0e-09	-0.71	0.62	0.26	FALSE
10	GTEx	Lung	FAM136A	0.10	0.00	lasso	3	0.00	4.3e-01	6.4	-7.6	3.6e-14	-0.83	0.06	0.16	FALSE
11	GTEx	Skin Not Sun Exposed Suprapubic	PCYOX1	0.14	0.03	lasso	6	0.02	2.2e-02	6.2	5.5	4.8e-08	0.72	0.10	0.41	FALSE
12	GTEx	Thyroid	SNRNP27	0.12	0.05	enet	11	0.06	1.6e-05	-5.3	-6.3	2.9e-10	-0.18	0.80	0.01	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	FAM136A	0.09	0.08	lasso	3	0.06	9.9e-09	6.3	-6.0	1.9e-09	-0.51	0.95	0.05	FALSE
14	YFS	Blood	PCYOX1	0.02	0.01	blup	461	0.01	1.1e-05	6.8	-5.4	6.0e-08	-0.61	0.02	0.98	FALSE
15	YFS	Blood	SNRNP27	0.05	0.05	bslmm	332	0.05	9.5e-17	4.7	-6.6	5.3e-11	-0.51	1.00	0.00	FALSE
16	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FAM136A	0.05	0.05	blup	42	0.04	1.3e-04	6.4	-6.8	1.3e-11	-0.74	0.02	0.95	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	FAM136A	0.03	0.04	lasso	2	0.03	1.3e-07	6.5	-6.5	8.0e-11	-0.74	0.51	0.49	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	SNRNP27	0.02	0.00	enet	5	0.01	2.5e-03	-4.9	-5.8	6.8e-09	-0.26	0.00	0.58	FALSE
19	The Cancer Genome Atlas	Colon Adenocarcinoma	FAM136A	0.10	0.12	lasso	2	0.12	3.0e-07	6.4	-6.5	1.1e-10	-0.74	0.74	0.20	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SNRNP27	0.04	0.02	blup	31	0.02	1.6e-03	-5.1	-5.2	2.1e-07	-0.08	0.01	0.96	FALSE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FAM136A	0.04	0.03	blup	42	0.04	6.0e-05	6.4	-7.2	4.5e-13	-0.88	0.04	0.93	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SNRNP27	0.09	0.02	blup	31	0.05	4.4e-06	-4.6	-6.3	2.3e-10	-0.28	0.01	0.98	TRUE
23	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FAM136A	0.07	0.03	lasso	3	0.04	1.6e-03	7.7	-7.5	7.1e-14	-0.91	0.00	0.94	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	C2orf42	0.04	0.01	blup	46	0.02	1.1e-03	6.9	-6.4	1.6e-10	-0.53	0.01	0.80	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	FAM136A	0.04	0.03	blup	42	0.03	1.2e-04	6.5	-6.0	1.5e-09	-0.80	0.17	0.81	FALSE
26	The Cancer Genome Atlas	Lung Adenocarcinoma	SNRNP27	0.06	0.06	enet	3	0.04	9.5e-06	-5.0	-5.9	4.2e-09	-0.18	0.01	0.99	FALSE
27	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SNRNP27	0.05	0.01	enet	3	0.03	1.7e-04	4.5	-5.9	3.8e-09	-0.28	0.02	0.66	FALSE
28	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	FAM136A	0.19	0.02	blup	42	0.07	7.5e-04	7.6	-5.4	5.4e-08	-0.66	0.01	0.87	FALSE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	SNRNP27	0.09	0.01	blup	31	0.03	5.1e-04	-5.3	-6.2	7.5e-10	-0.32	0.00	0.74	FALSE
30	The Cancer Genome Atlas	Soft Tissue Sarcoma	C2orf42	0.12	0.03	enet	17	0.05	1.0e-03	6.4	-5.9	4.7e-09	-0.54	0.04	0.21	FALSE
31	The Cancer Genome Atlas	Stomach Adenocarcinoma	FAM136A	0.04	0.04	lasso	4	0.04	8.5e-04	6.4	-6.6	3.3e-11	-0.85	0.03	0.71	FALSE
32	The Cancer Genome Atlas	Thyroid Carcinoma	FAM136A	0.05	0.04	lasso	3	0.04	4.5e-05	6.4	-6.8	9.9e-12	-0.83	0.02	0.98	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	SNRNP27	0.06	0.05	lasso	2	0.05	8.6e-06	-5.0	-5.3	1.1e-07	-0.09	0.01	0.97	FALSE