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chr1:22,648,411-25,558,152

Best TWAS P=5.89e-12 · Best GWAS P=8.27e-12 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	STPG1	0.25	0.10	enet	23	0.23	7.6e-19	6.37	6.4	1.4e-10	0.74	0.06	0.94	FALSE
2	GTEx	Artery Aorta	STPG1	0.34	0.12	enet	15	0.24	1.5e-13	5.74	5.8	7.5e-09	0.59	0.22	0.78	FALSE
3	GTEx	Artery Coronary	STPG1	0.29	0.10	lasso	3	0.19	5.8e-07	-3.38	5.6	2.7e-08	0.66	0.06	0.91	FALSE
4	GTEx	Artery Tibial	STPG1	0.21	0.09	enet	12	0.14	7.0e-11	5.74	5.9	3.5e-09	0.65	0.10	0.90	FALSE
5	GTEx	Artery Tibial	RCAN3	0.08	0.02	enet	15	0.04	3.6e-04	6.83	6.7	2.5e-11	0.80	0.00	0.99	FALSE
6	GTEx	Brain Cerebellar Hemisphere	ZNF436	0.19	-0.01	enet	12	0.00	4.1e-01	-4.20	-5.8	8.3e-09	0.03	0.02	0.60	FALSE
7	GTEx	Brain Frontal Cortex BA9	RP1-184J9.2	0.38	0.00	lasso	11	0.00	4.3e-01	-5.83	6.1	9.4e-10	0.02	0.02	0.64	TRUE
8	GTEx	Esophagus Muscularis	STPG1	0.12	0.07	enet	12	0.09	6.0e-06	6.37	5.2	1.7e-07	0.67	0.05	0.94	FALSE
9	GTEx	Liver	NIPAL3	0.47	0.13	lasso	11	0.15	7.3e-05	-5.12	-5.1	2.9e-07	-0.38	0.08	0.61	FALSE
10	GTEx	Muscle Skeletal	STPG1	0.17	0.07	enet	21	0.12	3.6e-12	-3.27	6.4	1.5e-10	0.66	0.03	0.97	FALSE
11	GTEx	Nerve Tibial	STPG1	0.30	0.20	lasso	6	0.22	7.6e-16	-3.39	5.5	3.3e-08	0.56	0.86	0.14	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	STPG1	0.17	0.08	enet	5	0.09	1.3e-05	6.37	6.9	5.9e-12	0.72	0.03	0.97	TRUE
13	GTEx	Skin Sun Exposed Lower leg	STPG1	0.21	0.16	lasso	5	0.15	9.2e-13	6.37	5.9	2.9e-09	0.68	0.05	0.95	FALSE
14	GTEx	Thyroid	NIPAL3	0.14	0.08	lasso	8	0.08	1.0e-06	-5.92	-5.3	1.2e-07	-0.49	0.04	0.96	TRUE
15	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C1orf130	0.09	0.08	enet	11	0.08	1.0e-04	-5.61	-5.1	3.0e-07	-0.54	0.01	0.98	FALSE
16	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	RCAN3	0.08	0.05	blup	59	0.06	7.1e-04	-5.48	-5.6	2.6e-08	-0.63	0.05	0.43	TRUE
17	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	HTR1D	0.24	0.12	lasso	4	0.12	1.2e-05	-5.82	5.4	5.8e-08	0.00	0.00	1.00	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	C1orf201	0.03	0.02	enet	5	0.03	5.0e-04	6.37	5.2	1.6e-07	0.40	0.02	0.80	TRUE
19	The Cancer Genome Atlas	Prostate Adenocarcinoma	GRHL3	0.10	0.02	enet	16	0.09	3.0e-09	-0.89	5.4	5.6e-08	0.58	0.08	0.87	FALSE